[ { "uniprot_canonical_ac": "Q03799-1", "uniprot_id": "RT08_YEAST", "mass": 17471.0, "length": 155, "protein_name": "Small ribosomal subunit protein uS8m", "gene_name": "MRPS8", "organism": "Yeast", "refseq_name": "mitochondrial 37S ribosomal protein uS8m MRPS8", "refseq_ac": "NP_013879", "gene_names_uniprotkb": "MRPS8; YM8520.07", "gene_names_refseq": "MRPS8; uS8m", "protein_names_uniprotkb": "Small ribosomal subunit protein uS8m; 37S ribosomal protein S8, mitochondrial", "protein_names_refseq": "mitochondrial 37S ribosomal protein uS8m MRPS8", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR158W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "12392552;14576278;17322287;24374639;25609543;28154081;9169872", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZX9", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q03799-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q03825-1", "uniprot_id": "MSS11_YEAST", "mass": 85050.0, "length": 758, "protein_name": "Transcription activator MSS11", "gene_name": "MSS11", "organism": "Yeast", "refseq_name": "Mss11p", "refseq_ac": "NP_013887", "gene_names_uniprotkb": "MSS11; YM8520.13C", "gene_names_refseq": "MSS11", "protein_names_uniprotkb": "Transcription activator MSS11; Multicopy suppressor of STA genes protein 11", "protein_names_refseq": "Mss11p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR164C)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "10515942;12492858;14523573;14562095;15466424;15485921;16568252;18001350;18202364;22814378;23749301;24374639;33229814;33481703;33491328;9169872;9342405;9832522;9987114", "class_list": "", "function": "Transcription factor that regulates pseudohyphal differentiation, invasive growth, floculation, adhesion and starch metabolism in response to nutrient availability., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 4, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 4, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 4, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 9, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VZY6", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:2000219 positive regulation of invasive growth in response to glucose limitation;GO:2000222 positive regulation of pseudohyphal growth;GO:1900735 positive regulation of flocculation", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "Q03825-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q03829-1", "uniprot_id": "MME1_YEAST", "mass": 40992.0, "length": 368, "protein_name": "Mitochondrial magnesium exporter 1", "gene_name": "MME1", "organism": "Yeast", "refseq_name": "Mme1p", "refseq_ac": "NP_013889", "gene_names_uniprotkb": "MME1; YM8520.15C", "gene_names_refseq": "MME1", "protein_names_uniprotkb": "Mitochondrial magnesium exporter 1", "protein_names_refseq": "Mme1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR166C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10930523;14562106;17322287;24374639;25585246;9169872", "class_list": "", "function": "Transporter of the mitochondrial inner membrane that exports magnesium and thus, plays a key role in mitochondrial Mg(2+) homeostasis., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZY8", "ec_number_list": "", "go_molecular_function": "GO:0015095 magnesium ion transmembrane transporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0015693 magnesium ion transport;GO:1990616 magnesium ion export from mitochondrion", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q03829-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q03856-1", "uniprot_id": "YD11A_YEAST", "mass": 49056.0, "length": 440, "protein_name": "Transposon Ty1-DR1 Gag polyprotein", "gene_name": "TY1A-DR1", "organism": "Yeast", "refseq_name": "gag protein", "refseq_ac": "NP_058141", "gene_names_uniprotkb": "TY1A-DR1; YD8557.07c; YDRCTy1-1 GAG", "gene_names_refseq": "", "protein_names_uniprotkb": "Transposon Ty1-DR1 Gag polyprotein; Gag-p45; Gag-p49; TY1A; TYA; Transposon Ty1 protein A; p54; p58", "protein_names_refseq": "gag protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR098C-A)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "11884596;15665377;16093660;19779198;24374639;9169867;9582191", "class_list": "", "function": "Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA also has nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VS85", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0075523 viral translational frameshifting", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q03856-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q03860-1", "uniprot_id": "TVP15_YEAST", "mass": 15882.0, "length": 143, "protein_name": "Golgi apparatus membrane protein TVP15", "gene_name": "TVP15", "organism": "Yeast", "refseq_name": "Tvp15p", "refseq_ac": "NP_010385", "gene_names_uniprotkb": "TVP15", "gene_names_refseq": "TVP15", "protein_names_uniprotkb": "Golgi apparatus membrane protein TVP15; TLG2 compartment vesicle protein 15; TLG2-vesicle protein of 15 kDa", "protein_names_refseq": "Tvp15p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR100W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562095;14562106;16107716;16847258;17178117;17322287;21126336;24374639;33491328;9169867", "class_list": "", "function": "Golgi membrane protein involved in vesicular trafficking., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS87", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0016192 vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q03860-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q03880-1", "uniprot_id": "PKR1_YEAST", "mass": 13962.0, "length": 122, "protein_name": "V-type ATPase assembly factor PKR1", "gene_name": "PKR1", "organism": "Yeast", "refseq_name": "Pkr1p", "refseq_ac": "NP_013842", "gene_names_uniprotkb": "PKR1; YM8564.05", "gene_names_refseq": "PKR1", "protein_names_uniprotkb": "V-type ATPase assembly factor PKR1", "protein_names_refseq": "Pkr1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR123W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562095;14562106;16847258;16926153;17322287;24374639;33491328;9169872", "class_list": "", "function": "Functions together with the other V-type ATPase assembly factors in the endoplasmic reticulum to efficiently assemble the V-type ATPase membrane sector V(0)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZU6", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q03880-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q03919-1", "uniprot_id": "RUB1_YEAST", "mass": 8693.0, "length": 77, "protein_name": "NEDD8-like protein RUB1", "gene_name": "RUB1", "organism": "Yeast", "refseq_name": "NEDD8 family protein RUB1", "refseq_ac": "NP_010423", "gene_names_uniprotkb": "RUB1; YD9302.15C", "gene_names_refseq": "RUB1", "protein_names_uniprotkb": "NEDD8-like protein RUB1; Related to ubiquitin protein 1; Ubiquitin-like protein RUB1", "protein_names_refseq": "NEDD8 family protein RUB1", "tax_id": 559292, "disease": "alcohol-associated liver disease (Disease Ontology:DOID:0070658); Parkinson's disease (Disease Ontology:DOID:14330); malignant astrocytoma (Disease Ontology:DOID:3069)", "pathway": " (sce:YDR139C); (R-SCE-5689603); (R-SCE-8856825); (R-SCE-8951664); (R-SCE-917937)", "pathway_count": 5, "publication_count": 7, "publication_id_list": "14519104;14562106;15988528;24374639;9169867;9531531;9545234", "class_list": "", "function": "Ubiquitin-like protein modifier that can be covalently attached to lysine residues of target proteins. Activated by the dimeric UBA3-ULA1 E1 enzyme and conjugated by the E2 UBC12 to substrate proteins. RUB1-conjugated (neddylated) substrate proteins include the cullins CDC53, RTT101 and CUL3, and the modification enhances the ubiquitin-ligase activity of the corresponding cullin-RING-based E3 ubiquitin-protein ligase complexes (CRLs)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSC2", "ec_number_list": "", "go_molecular_function": "GO:0031386 protein tag activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0030162 regulation of proteolysis;GO:0019941 modification-dependent protein catabolic process;GO:0045116 protein neddylation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q03919-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q03935-1", "uniprot_id": "YAP6_YEAST", "mass": 43597.0, "length": 383, "protein_name": "AP-1-like transcription factor YAP6", "gene_name": "YAP6", "organism": "Yeast", "refseq_name": "Yap6p", "refseq_ac": "NP_010545", "gene_names_uniprotkb": "YAP6; HAL7; YD9320A.09C; YD9320A.10C", "gene_names_refseq": "HAL7; YAP6", "protein_names_uniprotkb": "AP-1-like transcription factor YAP6", "protein_names_refseq": "Yap6p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR259C)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "11179441;12399584;14555958;14562106;17322287;19795423;19823750;21177495;23749301;24374639;33229814;33481703;33491328;9169867;9372930;9559673", "class_list": "", "function": "Transcription activator involved in the regulation of genes expressed in response to environmental changes and metabolic requirements. According to genome-wide promoter binding and gene expression studies it regulates, among others, genes involved in ribosome biogenesis, protein synthesis, carbohydrate metabolism, and carbohydrate transport. It may also be involved in pleiotropic drug resistance. When overexpressed, it confers resistance to cisplatin, methylmethanosulfonate, and mitomycin C, and increases cellular tolerance to sodium and lithium., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 4, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 4, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 4, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VSN9;Q03926;Q03931", "ec_number_list": "", "go_molecular_function": "GO:0001010 RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity;GO:0000976 transcription cis-regulatory region binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "Q03935-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q03937-1", "uniprot_id": "HED1_YEAST", "mass": 18258.0, "length": 162, "protein_name": "Meiosis-specific protein HED1", "gene_name": "HED1", "organism": "Yeast", "refseq_name": "Hed1p", "refseq_ac": "NP_001035220", "gene_names_uniprotkb": "HED1; YD9335.01", "gene_names_refseq": "HED1", "protein_names_uniprotkb": "Meiosis-specific protein HED1; RED1 suppressor protein 1", "protein_names_refseq": "Hed1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR014W-A)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "16818607;24374639;27483004;33491328;9169867", "class_list": "", "function": "Involved in regulation of meiotic recombination and repair of DNA damage. Inhibits RAD51-mediated recombination when the meiotic recombination machinery is impaired., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS01", "ec_number_list": "", "go_molecular_function": "GO:0004857 enzyme inhibitor activity", "go_cellular_component": "GO:0000794 condensed nuclear chromosome", "go_biological_process": "GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0007130 synaptonemal complex assembly;GO:0045950 negative regulation of mitotic recombination;GO:1903873 negative regulation of DNA recombinase mediator complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q03937-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q03942-1", "uniprot_id": "RKM2_YEAST", "mass": 55950.0, "length": 479, "protein_name": "Ribosomal lysine N-methyltransferase 2", "gene_name": "RKM2", "organism": "Yeast", "refseq_name": "protein-lysine N-methyltransferase", "refseq_ac": "NP_010484", "gene_names_uniprotkb": "RKM2", "gene_names_refseq": "RKM2", "protein_names_uniprotkb": "Ribosomal lysine N-methyltransferase 2; 2.1.1.-", "protein_names_refseq": "protein-lysine N-methyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR198C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562106;17005568;18957409;24374639;33491328;9169867", "class_list": "", "function": "S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that trimethylates 60S ribosomal protein L12 (RPL12A and RPL12B) at 'Lys-4' and 'Lys-11'., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSI1", "ec_number_list": "", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0042800 histone H3K4 methyltransferase activity;GO:0046975 histone H3K36 methyltransferase activity;GO:0016279 protein-lysine N-methyltransferase activity", "go_cellular_component": "", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0018026 peptidyl-lysine monomethylation;GO:0018023 peptidyl-lysine trimethylation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q03942-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q03956-1", "uniprot_id": "RAV2_YEAST", "mass": 40017.0, "length": 351, "protein_name": "Regulator of V-ATPase in vacuolar membrane protein 2", "gene_name": "RAV2", "organism": "Yeast", "refseq_name": "Rav2p", "refseq_ac": "NP_010488", "gene_names_uniprotkb": "RAV2; YD9346.12C", "gene_names_refseq": "RAV2", "protein_names_uniprotkb": "Regulator of V-ATPase in vacuolar membrane protein 2", "protein_names_refseq": "Rav2p", "tax_id": 559292, "disease": "Kohlschutter-Tonz syndrome (Disease Ontology:DOID:0111668)", "pathway": " (sce:YDR202C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "11283612;11844802;14562106;17322287;24374639;9169867", "class_list": "", "function": "Component of the RAVE complex, which is required for stable assembly of the vacuolar ATPase complex V-ATPase under many conditions. May be required for transport between the early endosome and the late endosome/prevacuolar compartment (PVC)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSI4", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0043291 RAVE complex;GO:0012505 endomembrane system;GO:0031901 early endosome membrane", "go_biological_process": "GO:0015031 protein transport;GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly;GO:0043254 regulation of protein-containing complex assembly;GO:0007035 vacuolar acidification", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q03956-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q03964-1", "uniprot_id": "YD17A_YEAST", "mass": 49445.0, "length": 440, "protein_name": "Transposon Ty1-DR2 Gag polyprotein", "gene_name": "TY1A-DR2", "organism": "Yeast", "refseq_name": "gag protein", "refseq_ac": "NP_010455", "gene_names_uniprotkb": "TY1A-DR2; YD9395.02", "gene_names_refseq": "", "protein_names_uniprotkb": "Transposon Ty1-DR2 Gag polyprotein; Gag-p45; Gag-p49; TY1A; TYA; Transposon Ty1 protein A; p54; p58", "protein_names_refseq": "gag protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR170W-A)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "17287358;19795423;19823750;24374639;9169867", "class_list": "", "function": "Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA also has nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VSF2", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q03964-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q03976-1", "uniprot_id": "RT24_YEAST", "mass": 37393.0, "length": 319, "protein_name": "Small ribosomal subunit protein mS35", "gene_name": "RSM24", "organism": "Yeast", "refseq_name": "mitochondrial 37S ribosomal protein mS35 RSM24", "refseq_ac": "NP_010460", "gene_names_uniprotkb": "RSM24", "gene_names_refseq": "RSM24; mS35", "protein_names_uniprotkb": "Small ribosomal subunit protein mS35; 37S ribosomal protein S24, mitochondrial; Mitochondrial ribosomal small subunit protein 24", "protein_names_refseq": "mitochondrial 37S ribosomal protein mS35 RSM24", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR175C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "11278769;12392552;14562095;14562106;14576278;17322287;19795423;19823750;24374639;25609543;28154081;33491328;9169867", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSF7", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q03976-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04004-1", "uniprot_id": "PLP1_YEAST", "mass": 26623.0, "length": 230, "protein_name": "Phosducin-like protein 1", "gene_name": "PLP1", "organism": "Yeast", "refseq_name": "Plp1p", "refseq_ac": "NP_010469", "gene_names_uniprotkb": "PLP1; YD9395.17", "gene_names_refseq": "PLP1", "protein_names_uniprotkb": "Phosducin-like protein 1", "protein_names_refseq": "Plp1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR183W)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "10749875;14562095;14562106;14573467;17322287;17330950;18407956;19684113;19779198;22814378;23749301;24374639;30516470;32597660;33481703;33491328;9169867", "class_list": "", "function": "Not essential for growth. Inhibits early G protein signaling events following pheromone stimulation. May help create heterodimerizable beta-tubulin by facilitating the efficient transfer of nascent beta-tubulin polypeptides to the folding apparatus., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSG7", "ec_number_list": "", "go_molecular_function": "GO:0031683 G-protein beta/gamma-subunit complex binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006457 protein folding;GO:0009968 negative regulation of signal transduction;GO:0071444 cellular response to pheromone", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q04004-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04005-1", "uniprot_id": "LIC4_YEAST", "mass": 33114.0, "length": 294, "protein_name": "Protein ATC1/LIC4", "gene_name": "ATC1", "organism": "Yeast", "refseq_name": "Atc1p", "refseq_ac": "NP_010470", "gene_names_uniprotkb": "ATC1; LIC4; YD9395.18c", "gene_names_refseq": "ATC1; LIC4", "protein_names_uniprotkb": "Protein ATC1/LIC4; AIP3 complex protein 1; Lithium comvertas protein 4", "protein_names_refseq": "Atc1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR184C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10102375;11065362;14562095;14562106;14975746;17322287;18407956;23749301;24374639;33229814;33481703;33491328;9169867", "class_list": "", "function": "Involved in cation homeostasis and in the regulation of the cation stress signaling cascades. Also involved in bipolar budding., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VSG8;Q6Q540", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0030003 intracellular monoatomic cation homeostasis;GO:0007121 bipolar cellular bud site selection", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q04005-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04007-1", "uniprot_id": "SND1_YEAST", "mass": 98331.0, "length": 877, "protein_name": "SRP-independent targeting protein 1", "gene_name": "SND1", "organism": "Yeast", "refseq_name": "Snd1p", "refseq_ac": "NP_010472", "gene_names_uniprotkb": "SND1", "gene_names_refseq": "SND1", "protein_names_uniprotkb": "SRP-independent targeting protein 1", "protein_names_refseq": "Snd1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR186C)", "pathway_count": 1, "publication_count": 25, "publication_id_list": "14562095;14562106;15665377;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22106047;22218487;22814378;23749301;24374639;27905431;30516470;32597660;33481703;33491328;9169867", "class_list": "", "function": "Functions in the SND pathway, a SRP (signal recognition particle) and GET (guided entry of tail-anchored proteins) independent pathway for targeting a broad range of substrate proteins to the endoplasmic reticulum. SND functions in parallel to GET in targeting proteins with downstream hydrophobic motifs., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 56, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSH0", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0015031 protein transport", "synthesized_glycan_count": 0, "hit_score": 2.6, "record_id": "Q04007-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04031-1", "uniprot_id": "RRP17_YEAST", "mass": 27974.0, "length": 235, "protein_name": "Ribosomal RNA-processing protein 17", "gene_name": "RRP17", "organism": "Yeast", "refseq_name": "rRNA-processing protein RRP17", "refseq_ac": "NP_010700", "gene_names_uniprotkb": "RRP17", "gene_names_refseq": "RRP17", "protein_names_uniprotkb": "Ribosomal RNA-processing protein 17", "protein_names_refseq": "rRNA-processing protein RRP17", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR412W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "10684247;14562095;14562106;17330950;19779198;21126336;24374639;33491328;9169867", "class_list": "", "function": "Essential protein involved in ribosomal RNA processing., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VT44", "ec_number_list": "", "go_molecular_function": "GO:1990275 preribosome binding;GO:0019843 rRNA binding;GO:0004534 5'-3' RNA exonuclease activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0034399 nuclear periphery", "go_biological_process": "GO:0006364 rRNA processing;GO:0000477 generation of mature 5'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q04031-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04052-1", "uniprot_id": "ARO80_YEAST", "mass": 108205.0, "length": 950, "protein_name": "Transcriptional activator ARO80", "gene_name": "ARO80", "organism": "Yeast", "refseq_name": "Aro80p", "refseq_ac": "NP_010709", "gene_names_uniprotkb": "ARO80; D9461.10", "gene_names_refseq": "ARO80", "protein_names_uniprotkb": "Transcriptional activator ARO80", "protein_names_refseq": "Aro80p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR421W)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10207060;14562095;14562106;17330950;17563356;18407956;19795423;19823750;23749301;24374639;33481703;33491328;9169867", "class_list": "", "function": "Transcription activator required for the expression of genes involved in the catabolism of aromatic amino acids such as the aromatic aminotransferase II ARO9 and the phenylpyruvate decarboxylase ARO10., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 16, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VT51", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006569 L-tryptophan catabolic process;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0009083 branched-chain amino acid catabolic process;GO:0006559 L-phenylalanine catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q04052-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04066-1", "uniprot_id": "KFA_YEAST", "mass": 29991.0, "length": 261, "protein_name": "Kynurenine formamidase", "gene_name": "BNA7", "organism": "Yeast", "refseq_name": "arylformamidase", "refseq_ac": "NP_010716", "gene_names_uniprotkb": "BNA7", "gene_names_refseq": "BNA7", "protein_names_uniprotkb": "Kynurenine formamidase; 3.5.1.9; Arylformamidase; Biosynthesis of nicotinic acid protein 7; FKF; KFA; KFase; N-formylkynurenine formamidase", "protein_names_refseq": "arylformamidase", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR428C)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "14645503;15624212;15665377;17330950;18205391;18407956;19779198;20702584;21126336;21177495;22218487;23749301;24374639;30516470;32597660;33481703;33491328;9169867", "class_list": "", "function": "Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites., [UniProtKB, HAMAP, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VT57", "ec_number_list": "3.5.1.9", "go_molecular_function": "GO:0004061 arylformamidase activity", "go_cellular_component": "", "go_biological_process": "GO:0019441 L-tryptophan catabolic process to kynurenine;GO:0030307 positive regulation of cell growth;GO:0009435 NAD+ biosynthetic process;GO:0034354 'de novo' NAD+ biosynthetic process from L-tryptophan", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "Q04066-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04081-1", "uniprot_id": "LCMT1_YEAST", "mass": 37695.0, "length": 328, "protein_name": "Leucine carboxyl methyltransferase 1", "gene_name": "PPM1", "organism": "Yeast", "refseq_name": "leucine carboxy methyltransferase", "refseq_ac": "NP_010723", "gene_names_uniprotkb": "PPM1", "gene_names_refseq": "PPM1", "protein_names_uniprotkb": "Leucine carboxyl methyltransferase 1; 2.1.1.233; Protein phosphatase methyltransferase 1; [Phosphatase 2A protein]-leucine-carboxy methyltransferase 1", "protein_names_refseq": "leucine carboxy methyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR435C); (R-SCE-69273)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "11060018;11697862;14660564;24374639;9169867", "class_list": "", "function": "Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues. Acts on the two major protein phosphatase 2A catalytic subunits, PPH21 and PPH22., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VT62", "ec_number_list": "3.1.3.16;2.1.1.233", "go_molecular_function": "GO:0018423 protein C-terminal leucine carboxyl O-methyltransferase activity", "go_cellular_component": "", "go_biological_process": "GO:0010506 regulation of autophagy;GO:0006481 C-terminal protein methylation;GO:0065003 protein-containing complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q04081-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04083-1", "uniprot_id": "THI74_YEAST", "mass": 41385.0, "length": 370, "protein_name": "Thiamine-repressible mitochondrial transport protein THI74", "gene_name": "THI74", "organism": "Yeast", "refseq_name": "Thi74p", "refseq_ac": "NP_010726", "gene_names_uniprotkb": "THI74", "gene_names_refseq": "THI74", "protein_names_uniprotkb": "Thiamine-repressible mitochondrial transport protein THI74", "protein_names_refseq": "Thi74p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR438W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "12524434;16847258;16850348;24374639;9169867", "class_list": "", "function": "May be involved in thiaminediphosphate transport across the mitochondrial membrane., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VT65", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0031966 mitochondrial membrane;GO:0000324 fungal-type vacuole", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q04083-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04116-1", "uniprot_id": "YHP1_YEAST", "mass": 39598.0, "length": 353, "protein_name": "Homeobox protein YHP1", "gene_name": "YHP1", "organism": "Yeast", "refseq_name": "Yhp1p", "refseq_ac": "NP_010739", "gene_names_uniprotkb": "YHP1; D9461.36", "gene_names_refseq": "YHP1", "protein_names_uniprotkb": "Homeobox protein YHP1", "protein_names_refseq": "Yhp1p", "tax_id": 559292, "disease": "anterior segment dysgenesis (Disease Ontology:DOID:0060648); syndromic X-linked intellectual disability Hedera type (Disease Ontology:DOID:0060806); syndromic microphthalmia 16 (Disease Ontology:DOID:0060842); Leri-Weill dyschondrosteosis (Disease Ontology:DOID:0060847); combined pituitary hormone deficiency 2 (Disease Ontology:DOID:0061020); retinitis pigmentosa 95 (Disease Ontology:DOID:0061112); developmental and epileptic encephalopathy 1 (Disease Ontology:DOID:0080468); anterior segment dysgenesis 1 (Disease Ontology:DOID:0080606); frontonasal dysplasia 1 (Disease Ontology:DOID:0081045); frontonasal dysplasia 3 (Disease Ontology:DOID:0081047); age related macular degeneration 6 (Disease Ontology:DOID:0110018); cataract 11 multiple types (Disease Ontology:DOID:0110249); cataract 9 multiple types (Disease Ontology:DOID:0110266); cone-rod dystrophy 11 (Disease Ontology:DOID:0111018); non-syndromic X-linked intellectual disability ARX-related (Disease Ontology:DOID:0112021); SHOX-related short stature (Disease Ontology:DOID:0112120); corpus callosum agenesis-abnormal genitalia syndrome (Disease Ontology:DOID:0112151); X-linked lissencephaly 2 (Disease Ontology:DOID:0112238); clubfoot (Disease Ontology:DOID:11836); lung cancer (Disease Ontology:DOID:1324); Axenfeld-Rieger syndrome (Disease Ontology:DOID:14686); Partington syndrome (Disease Ontology:DOID:14744); epilepsy (Disease Ontology:DOID:1826); hypogonadism (Disease Ontology:DOID:1924); cataract (Disease Ontology:DOID:83); type 2 diabetes mellitus (Disease Ontology:DOID:9352); hypopituitarism (Disease Ontology:DOID:9406)", "pathway": " (sce:YDR451C)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10705372;11097841;12464632;12464633;17287358;19795423;19823750;21177495;23749301;24374639;32597660;33481703;33491328;9169867", "class_list": "", "function": "Transcriptional repressor required to restrict transcription of ECB-dependent genes to the G1/M phase by repressing their transcription during S late phase. Genes that contain a ECB (early cell box) element in their transcription regulatory region are transcribed only during G1/M phases. Binds the IMEI regulatory region in vitro, its relevance in vivo is however unclear., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 27, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VT76", "ec_number_list": "", "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0000082 G1/S transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q04116-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04172-1", "uniprot_id": "SHE9_YEAST", "mass": 53571.0, "length": 456, "protein_name": "Sensitive to high expression protein 9, mitochondrial", "gene_name": "SHE9", "organism": "Yeast", "refseq_name": "She9p", "refseq_ac": "NP_010681", "gene_names_uniprotkb": "SHE9; D9509.13; MDM33", "gene_names_refseq": "MDM33; SHE9", "protein_names_uniprotkb": "Sensitive to high expression protein 9, mitochondrial; Mitochondrial distribution and morphology protein 33", "protein_names_refseq": "She9p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR393W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "11907266;12591915;14562106;20489023;24374639;7762298;9169867", "class_list": "", "function": "Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology. Causes growth arrest when highly overexpressed., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VT27", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0007005 mitochondrion organization;GO:0007007 inner mitochondrial membrane organization", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q04172-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04174-1", "uniprot_id": "SMP3_YEAST", "mass": 59883.0, "length": 516, "protein_name": "GPI mannosyltransferase 4", "gene_name": "SMP3", "organism": "Yeast", "refseq_name": "glycosylphosphatidylinositol-alpha 1,2 mannosyltransferase", "refseq_ac": "NP_014792", "gene_names_uniprotkb": "SMP3; LAS2; SAP2", "gene_names_refseq": "LAS2; SAP2; SMP3", "protein_names_uniprotkb": "GPI mannosyltransferase 4; 2.4.1.-; GPI mannosyltransferase IV; GPI-MT-IV", "protein_names_refseq": "glycosylphosphatidylinositol-alpha 1,2 mannosyltransferase", "tax_id": 559292, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (sce:YOR149C); (R-SCE-162710)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "11356840;16847258;2005867;24374639;9046089;9169874", "class_list": "", "function": "Alpha-1,2-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers a fourth mannose to trimannosyl-GPIs during GPI precursor assembly. The presence of a fourth mannose in GPI is essential in fungi. Involved in plasmid maintenance with SMP2., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6W2K6;Q99400", "ec_number_list": "2.4.1.-", "go_molecular_function": "GO:0000026 alpha-1,2-mannosyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006506 GPI anchor biosynthetic process;GO:0006276 plasmid maintenance", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q04174-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04183-1", "uniprot_id": "TR120_YEAST", "mass": 147662.0, "length": 1289, "protein_name": "Trafficking protein particle complex II-specific subunit 120", "gene_name": "TRS120", "organism": "Yeast", "refseq_name": "TRAPPII-specific subunit TRS120", "refseq_ac": "NP_010695", "gene_names_uniprotkb": "TRS120; D9509.25; ESBP10", "gene_names_refseq": "TRS120", "protein_names_uniprotkb": "Trafficking protein particle complex II-specific subunit 120; TRAPP II-specific subunit 120; Transport protein particle 120 kDa subunit", "protein_names_refseq": "TRAPPII-specific subunit TRS120", "tax_id": 559292, "disease": "autosomal recessive intellectual developmental disorder 13 (Disease Ontology:DOID:0081098); intellectual disability (Disease Ontology:DOID:1059); attention deficit hyperactivity disorder (Disease Ontology:DOID:1094)", "pathway": " (sce:YDR407C); (R-SCE-204005); (R-SCE-8876198)", "pathway_count": 3, "publication_count": 22, "publication_id_list": "11239471;11875433;14562106;15665377;17330950;17475775;18407956;19779198;19795423;19823750;20972447;21126336;22118465;23749301;24374639;32597660;33229814;33481703;33491328;34965436;9169867;9564032", "class_list": "", "function": "Specific subunit of the TRAPP II complex, a highly conserved vesicle tethering complex that functions in the late Golgi as a guanine nucleotide exchanger (GEF) for the Golgi YPT1 GTPase. TRS120 plays a role in the YPT GEF activity of TRAPP II in concert with the two other TRAPP II-specific subunits TRS65 and TRS130., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 7, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 7, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 7, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 23, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 3, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "D6VT39;Q05731", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005769 early endosome;GO:0005829 cytosol;GO:0005802 trans-Golgi network;GO:1990071 TRAPPII protein complex", "go_biological_process": "GO:0042147 retrograde transport, endosome to Golgi;GO:0006891 intra-Golgi vesicle-mediated transport;GO:0034498 early endosome to Golgi transport", "synthesized_glycan_count": 0, "hit_score": 3.1, "record_id": "Q04183-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04201-1", "uniprot_id": "CUE4_YEAST", "mass": 12893.0, "length": 117, "protein_name": "CUE domain-containing protein CUE4", "gene_name": "CUE4", "organism": "Yeast", "refseq_name": "Cue4p", "refseq_ac": "NP_013607", "gene_names_uniprotkb": "CUE4", "gene_names_refseq": "CUE4", "protein_names_uniprotkb": "CUE domain-containing protein CUE4; Coupling of ubiquitin conjugation to ER degradation protein 4", "protein_names_refseq": "Cue4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YML101C)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "11914276;12628920;14562095;14562106;17563356;18407956;19779198;21177495;22106047;22218487;23749301;24374639;27821475;32597660;33481703;33491328;9169872", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0I3", "ec_number_list": "", "go_molecular_function": "GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q04201-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04210-1", "uniprot_id": "YET2_YEAST", "mass": 19178.0, "length": 160, "protein_name": "Endoplasmic reticulum transmembrane protein 2", "gene_name": "YET2", "organism": "Yeast", "refseq_name": "Yet2p", "refseq_ac": "NP_013754", "gene_names_uniprotkb": "YET2; YM9532.05", "gene_names_refseq": "YET2", "protein_names_uniprotkb": "Endoplasmic reticulum transmembrane protein 2", "protein_names_refseq": "Yet2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR040W)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "16847258;24374639;9169872", "class_list": "", "function": "May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZL5", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0070973 protein localization to endoplasmic reticulum exit site", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q04210-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04212-1", "uniprot_id": "ARA2_YEAST", "mass": 38220.0, "length": 335, "protein_name": "D-arabinose 1-dehydrogenase", "gene_name": "ARA2", "organism": "Yeast", "refseq_name": "D-arabinose 1-dehydrogenase (NAD(P)(+)) ARA2", "refseq_ac": "NP_013755", "gene_names_uniprotkb": "ARA2; YM9532.06C", "gene_names_refseq": "ARA2", "protein_names_uniprotkb": "D-arabinose 1-dehydrogenase; 1.1.1.116; NAD(+)-specific D-arabinose dehydrogenase", "protein_names_refseq": "D-arabinose 1-dehydrogenase (NAD(P)(+)) ARA2", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR041C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "17097644;21177495;24374639;9169872", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZL6;Q1XGQ6", "ec_number_list": "1.1.1.117;1.1.1.116", "go_molecular_function": "GO:0045290 D-arabinose 1-dehydrogenase [NAD(P)+] activity;GO:0047816 D-arabinose 1-dehydrogenase (NAD+) activity", "go_cellular_component": "", "go_biological_process": "GO:0070485 dehydro-D-arabinono-1,4-lactone biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q04212-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04213-1", "uniprot_id": "IOC4_YEAST", "mass": 55427.0, "length": 475, "protein_name": "ISWI one complex protein 4", "gene_name": "IOC4", "organism": "Yeast", "refseq_name": "Ioc4p", "refseq_ac": "NP_013758", "gene_names_uniprotkb": "IOC4; YM9532.09", "gene_names_refseq": "IOC4", "protein_names_uniprotkb": "ISWI one complex protein 4", "protein_names_refseq": "Ioc4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR044W)", "pathway_count": 1, "publication_count": 21, "publication_id_list": "12482963;14562095;14562106;14622597;15665377;17330950;17563356;18407956;19779198;19795423;19823750;20702584;21126336;22218487;23749301;24374639;30516470;32597660;33481703;33491328;9169872", "class_list": "", "function": "Functions as a component of the ISW1B complex, which acts in remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. The ISW1B complex acts within coding regions to control the amount of RNA polymerase II released into productive elongation and to coordinate elongation with termination and pre-mRNA processing., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZL9", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0036437 Isw1b complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0009408 response to heat;GO:0007062 sister chromatid cohesion", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "Q04213-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04215-1", "uniprot_id": "YM13A_YEAST", "mass": 49274.0, "length": 440, "protein_name": "Transposon Ty1-MR1 Gag polyprotein", "gene_name": "TY1A-MR1", "organism": "Yeast", "refseq_name": "gag protein", "refseq_ac": "NP_013760", "gene_names_uniprotkb": "TY1A-MR1; YM9532.11C; YMRCTy1-3 GAG", "gene_names_refseq": "", "protein_names_uniprotkb": "Transposon Ty1-MR1 Gag polyprotein; Gag-p45; Gag-p49; TY1A; TYA; Transposon Ty1 protein A; p54; p58", "protein_names_refseq": "gag protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR046C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "11884596;16093660;17330950;18407956;19779198;24374639;9169872;9582191", "class_list": "", "function": "Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA also has nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VZM1", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0075523 viral translational frameshifting", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q04215-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04216-1", "uniprot_id": "DLT1_YEAST", "mass": 39187.0, "length": 342, "protein_name": "Defect at low temperature protein 1", "gene_name": "DLT1", "organism": "Yeast", "refseq_name": "Dlt1p", "refseq_ac": "NP_013845", "gene_names_uniprotkb": "DLT1; YM9553.02C", "gene_names_refseq": "DLT1", "protein_names_uniprotkb": "Defect at low temperature protein 1", "protein_names_refseq": "Dlt1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR126C)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "14562106;14968429;16847258;17078969;17563356;18245339;18407956;19684113;19795423;19823750;20702584;21126336;23749301;24374639;32597660;33481703;33491328;9169872", "class_list": "", "function": "Required for growth under high-pressure and low-temperature conditions., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VZU9", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "Q04216-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04225-1", "uniprot_id": "RRB1_YEAST", "mass": 57261.0, "length": 511, "protein_name": "Ribosome assembly protein RRB1", "gene_name": "RRB1", "organism": "Yeast", "refseq_name": "ribosome biosynthesis protein RRB1", "refseq_ac": "NP_013850", "gene_names_uniprotkb": "RRB1; YM9553.07C", "gene_names_refseq": "RRB1", "protein_names_uniprotkb": "Ribosome assembly protein RRB1", "protein_names_refseq": "ribosome biosynthesis protein RRB1", "tax_id": 559292, "disease": "congenital diarrhea (Disease Ontology:DOID:0060774)", "pathway": " (sce:YMR131C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "11728313;18407956;19779198;19795423;19823750;20702584;23749301;24374639;33481703;33491328;9169872", "class_list": "", "function": "Involved in regulation of L3 expression and stability and plays a role in early 60S ribosomal subunit assembly. May be required for proper assembly of pre-ribosomal particles during early ribosome biogenesis, presumably by targeting L3 onto the 35S precursor rRNA., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZV4", "ec_number_list": "", "go_molecular_function": "GO:0051082 unfolded protein binding", "go_cellular_component": "GO:0005730 nucleolus", "go_biological_process": "GO:0042254 ribosome biogenesis;GO:0006364 rRNA processing", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q04225-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04233-1", "uniprot_id": "GIS4_YEAST", "mass": 87140.0, "length": 774, "protein_name": "Protein GIS4", "gene_name": "GIS4", "organism": "Yeast", "refseq_name": "Gis4p", "refseq_ac": "NP_013708", "gene_names_uniprotkb": "GIS4; YM9571.13C", "gene_names_refseq": "GIS4", "protein_names_uniprotkb": "Protein GIS4", "protein_names_refseq": "Gis4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YML006C)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "10628841;14562095;14562106;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20489023;20702584;21126336;21177495;22218487;23749301;24374639;30516470;32597660;33481703;33491328;9169872", "class_list": "", "function": "May be involved in the Ras/cAMP signaling pathway., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 33, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZG9", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0006873 intracellular monoatomic ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "Q04233-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04279-1", "uniprot_id": "SEG1_YEAST", "mass": 105874.0, "length": 960, "protein_name": "Eisosome protein SEG1", "gene_name": "SEG1", "organism": "Yeast", "refseq_name": "Seg1p", "refseq_ac": "NP_013803", "gene_names_uniprotkb": "SEG1; YM9582.10", "gene_names_refseq": "SEG1", "protein_names_uniprotkb": "Eisosome protein SEG1; Stability of eisosomes guaranteed protein 1", "protein_names_refseq": "Seg1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR086W)", "pathway_count": 1, "publication_count": 27, "publication_id_list": "11914276;15665377;17287358;17322287;17330950;17563356;18407956;19269952;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22218487;22368779;22869600;23749301;24374639;24909858;30516470;32597660;33229814;33481703;33491328;9169872", "class_list": "", "function": "Important for the biogenesis of eisosomes, large cytoplasmic protein assemblies that localize to specialized domains on the plasma membrane to cluster specific proteins at sites of membrane invaginations. Required for efficient incorporation of the eisosome component PIL1 into eisosomes., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 93, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VZQ9;Q6B304", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:0032126 eisosome", "go_biological_process": "GO:0070941 eisosome assembly", "synthesized_glycan_count": 0, "hit_score": 3.2, "record_id": "Q04279-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04299-1", "uniprot_id": "YMX7_YEAST", "mass": 32067.0, "length": 284, "protein_name": "Probable ADP-ribose 1''-phosphate phosphatase YML087W", "gene_name": "YM9582.12", "organism": "Yeast", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "YM9582.12", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable ADP-ribose 1''-phosphate phosphatase YML087W; 3.1.3.84", "protein_names_refseq": "", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR087W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "15722447;17322287;24374639;9169872", "class_list": "", "function": "Highly specific phosphatase involved in the metabolism of ADP-ribose 1''-phosphate (Appr1p) which is produced as a consequence of tRNA splicing. + phosphate., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZR0", "ec_number_list": "3.2.2.-;3.1.3.84", "go_molecular_function": "GO:0016787 hydrolase activity", "go_cellular_component": "", "go_biological_process": "GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q04299-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04301-1", "uniprot_id": "VBA1_YEAST", "mass": 62640.0, "length": 562, "protein_name": "Vacuolar basic amino acid transporter 1", "gene_name": "VBA1", "organism": "Yeast", "refseq_name": "Vba1p", "refseq_ac": "NP_013806", "gene_names_uniprotkb": "VBA1; YM9582.13C", "gene_names_refseq": "VBA1", "protein_names_uniprotkb": "Vacuolar basic amino acid transporter 1", "protein_names_refseq": "Vba1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR088C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "15572352;16847258;24374639;33481703;9169872", "class_list": "", "function": "Transporter required for vacuolar uptake of at least histidine and lysine., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VZR1", "ec_number_list": "", "go_molecular_function": "GO:0015174 basic amino acid transmembrane transporter activity", "go_cellular_component": "GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0015802 basic amino acid transport;GO:0055085 transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q04301-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04329-1", "uniprot_id": "ICY1_YEAST", "mass": 14337.0, "length": 127, "protein_name": "Interacting with cytoskeleton protein 1", "gene_name": "ICY1", "organism": "Yeast", "refseq_name": "Icy1p", "refseq_ac": "NP_013922", "gene_names_uniprotkb": "ICY1; YM9646.08", "gene_names_refseq": "ICY1", "protein_names_uniprotkb": "Interacting with cytoskeleton protein 1", "protein_names_refseq": "Icy1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR195W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "12673624;14504216;14562095;14562106;15843968;17322287;24374639;9169872", "class_list": "", "function": "Required for viability of cells lacking mtDNA., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W020", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000329 fungal-type vacuole membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q04329-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04341-1", "uniprot_id": "MIX14_YEAST", "mass": 13866.0, "length": 121, "protein_name": "Mitochondrial intermembrane space cysteine motif-containing protein MIX14", "gene_name": "MIX14", "organism": "Yeast", "refseq_name": "Mix14p", "refseq_ac": "NP_010314", "gene_names_uniprotkb": "MIX14; MIC14; YD9673.01", "gene_names_refseq": "MIC14; MIX14", "protein_names_uniprotkb": "Mitochondrial intermembrane space cysteine motif-containing protein MIX14; Mitochondrial intermembrane space CX(n)C motif protein of 14 kDa", "protein_names_refseq": "Mix14p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR031W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "17095012;22984289;24374639;24687277;9169867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS15;Q07789", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005758 mitochondrial intermembrane space", "go_biological_process": "GO:0009060 aerobic respiration;GO:0045333 cellular respiration", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q04341-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04347-1", "uniprot_id": "BUD22_YEAST", "mass": 60054.0, "length": 519, "protein_name": "Bud site selection protein 22", "gene_name": "BUD22", "organism": "Yeast", "refseq_name": "Bud22p", "refseq_ac": "NP_013727", "gene_names_uniprotkb": "BUD22; YM9711.01", "gene_names_refseq": "BUD22", "protein_names_uniprotkb": "Bud site selection protein 22", "protein_names_refseq": "Bud22p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR014W)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "11452010;14562095;14562106;17287358;17322287;17330950;17563356;18407956;19779198;19795423;19823750;20702584;21126336;21177495;21725298;23749301;24374639;30516470;32597660;33481703;33491328;9169872", "class_list": "", "function": "Involved in positioning the proximal bud pole signal., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 19, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZI8;Q6B299", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0030686 90S preribosome", "go_biological_process": "GO:0042274 ribosomal small subunit biogenesis;GO:0030490 maturation of SSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "Q04347-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04383-1", "uniprot_id": "PLM2_YEAST", "mass": 58202.0, "length": 521, "protein_name": "Protein PLM2", "gene_name": "PLM2", "organism": "Yeast", "refseq_name": "Plm2p", "refseq_ac": "NP_010789", "gene_names_uniprotkb": "PLM2", "gene_names_refseq": "PLM2", "protein_names_uniprotkb": "Protein PLM2; Plasmid maintenance protein 2", "protein_names_refseq": "Plm2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR501W)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "11206552;12464632;14574415;15965243;17287358;17563356;18407956;20190278;21177495;23749301;24374639;32597660;33481703;33491328;9169867", "class_list": "", "function": "Binds to the promoters of genes with functions important for the G1/S (start) transition; primarily genes involved in DNA synthesis and repair, chromosome segregation, nuclear division and transcription., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 26, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VTC3", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0006974 DNA damage response", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q04383-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04399-1", "uniprot_id": "GMC1_YEAST", "mass": 69281.0, "length": 608, "protein_name": "Putative multicopper oxidase GMC1", "gene_name": "GMC1", "organism": "Yeast", "refseq_name": "putative oxidoreductase", "refseq_ac": "NP_010794", "gene_names_uniprotkb": "GMC1; D9719.12", "gene_names_refseq": "GMC1", "protein_names_uniprotkb": "Putative multicopper oxidase GMC1; 1.-.-.-; Grand meiotic recombination cluster protein 1", "protein_names_refseq": "putative oxidoreductase", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR506C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "14562106;22194413;24374639;9169867", "class_list": "", "function": "Could be an iron transport multicopper oxidase, which is required for Fe(2+) high affinity uptake. May be required to oxidize Fe(2+) and release it from the transporter. Essential component of copper-dependent iron transport (By similarity). Involved in meiotic prophase and synaptonemal complex (SC) assembly., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTC8", "ec_number_list": "", "go_molecular_function": "GO:0005507 copper ion binding;GO:0004322 ferroxidase activity", "go_cellular_component": "GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0051321 meiotic cell cycle;GO:0010106 cellular response to iron ion starvation;GO:0070193 synaptonemal complex organization;GO:0033215 reductive iron assimilation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q04399-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04411-1", "uniprot_id": "URC2_YEAST", "mass": 88648.0, "length": 772, "protein_name": "Uracil catabolism protein 2", "gene_name": "URC2", "organism": "Yeast", "refseq_name": "Urc2p", "refseq_ac": "NP_010808", "gene_names_uniprotkb": "URC2", "gene_names_refseq": "RRT4; URC2", "protein_names_uniprotkb": "Uracil catabolism protein 2", "protein_names_refseq": "Urc2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR520C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562095;14562106;16464826;17322287;24374639;32597660;33491328;9169867", "class_list": "", "function": "Probable transcriptional activator involved in uracil catabolism., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTE1", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0019858 cytosine metabolic process;GO:0006212 uracil catabolic process;GO:0006351 DNA-templated transcription;GO:0009117 nucleotide metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q04411-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04412-1", "uniprot_id": "AGE1_YEAST", "mass": 54494.0, "length": 482, "protein_name": "ADP-ribosylation factor GTPase-activating protein effector protein 1", "gene_name": "AGE1", "organism": "Yeast", "refseq_name": "GTPase-activating protein AGE1", "refseq_ac": "NP_010812", "gene_names_uniprotkb": "AGE1; D9719.28; SAT1", "gene_names_refseq": "AGE1; SAT1", "protein_names_uniprotkb": "ADP-ribosylation factor GTPase-activating protein effector protein 1; ARF GAP effector protein 1; Suppressor of ARF1 thermosensitive mutant protein 1", "protein_names_refseq": "GTPase-activating protein AGE1", "tax_id": 559292, "disease": "colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (sce:YDR524C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "12627398;14562095;14562106;21126336;21177495;24374639;32597660;33481703;33491328;9169867;9677411", "class_list": "", "function": "GTPase-activating protein (GAP) for the ADP ribosylation factors ARF1 and ARF2. May be involved in the endocytic pathway., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTE4", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005543 phospholipid binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005768 endosome;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0015031 protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006891 intra-Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q04412-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04418-1", "uniprot_id": "RBA50_YEAST", "mass": 50192.0, "length": 439, "protein_name": "RNA polymerase II-associated protein RBA50", "gene_name": "RBA50", "organism": "Yeast", "refseq_name": "Rba50p", "refseq_ac": "NP_010816", "gene_names_uniprotkb": "RBA50", "gene_names_refseq": "RBA50", "protein_names_uniprotkb": "RNA polymerase II-associated protein RBA50; RNA polymerase II-associated protein of 50 kDa", "protein_names_refseq": "Rba50p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR527W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "12161108;14562095;14562106;14690591;15282305;19779198;24374639;33481703;33491328;9169867", "class_list": "", "function": "Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTE8", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006366 transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q04418-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04429-1", "uniprot_id": "HLR1_YEAST", "mass": 47578.0, "length": 423, "protein_name": "Protein HLR1", "gene_name": "HLR1", "organism": "Yeast", "refseq_name": "Hlr1p", "refseq_ac": "NP_010817", "gene_names_uniprotkb": "HLR1; D9719.31", "gene_names_refseq": "HLR1", "protein_names_uniprotkb": "Protein HLR1; LRE1 homolog", "protein_names_refseq": "Hlr1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR528W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "11532139;11580836;14562095;14562106;19684113;19779198;23749301;24374639;32597660;33481703;33491328;9169867", "class_list": "", "function": "Involved in cell wall composition and integrity and response to osmotic stress., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 27, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTE9", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q04429-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04430-1", "uniprot_id": "PANK_YEAST", "mass": 40903.0, "length": 367, "protein_name": "Pantothenate kinase CAB1", "gene_name": "CAB1", "organism": "Yeast", "refseq_name": "pantothenate kinase", "refseq_ac": "NP_010820", "gene_names_uniprotkb": "CAB1", "gene_names_refseq": "CAB1", "protein_names_uniprotkb": "Pantothenate kinase CAB1; 2.7.1.33; Coenzyme A biosynthesis protein 1; Pantothenic acid kinase CAB1", "protein_names_refseq": "pantothenate kinase", "tax_id": 559292, "disease": "pantothenate kinase-associated neurodegeneration (Disease Ontology:DOID:3981); cataract (Disease Ontology:DOID:83)", "pathway": " (sce:YDR531W); (R-SCE-199220)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "14562095;14562106;17330950;19266201;24374639;33491328;34965436;9169867", "class_list": "", "function": "Plays a role in the physiological regulation of the intracellular CoA concentration., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTF2", "ec_number_list": "2.7.1.33", "go_molecular_function": "GO:0005524 ATP binding;GO:0004594 pantothenate kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0015937 coenzyme A biosynthetic process;GO:0008204 ergosterol metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q04430-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04471-1", "uniprot_id": "YM04_YEAST", "mass": 42901.0, "length": 368, "protein_name": "Abasic site processing protein YMR114C", "gene_name": "YM9718.13C", "organism": "Yeast", "refseq_name": "putative peptide hydrolase", "refseq_ac": "NP_013832", "gene_names_uniprotkb": "YM9718.13C", "gene_names_refseq": "", "protein_names_uniprotkb": "Abasic site processing protein YMR114C; 3.4.-.-; 4.-.-.-; Peptidase YMR114C", "protein_names_refseq": "putative peptide hydrolase", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR114C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "17287358;18407956;23749301;24374639;32597660;33481703;33491328;9169872", "class_list": "", "function": "Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA: forms a stable thiazolidine linkage between a ring-opened abasic site and the alpha-amino and sulfhydryl substituents of its N-terminal catalytic cysteine residue. The DNA-protein cross-link is then reversed: able to catalyze the reversal of the thiazolidine cross-link and cycle between a cross-link and a non-cross-linked state depending on DNA context: mediates self-reversal of the thiazolidine cross-link in double stranded DNA. Acts as a protease: mediates autocatalytic processing of its N-terminal methionine in order to expose the catalytic cysteine., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZT7", "ec_number_list": "", "go_molecular_function": "GO:0008233 peptidase activity;GO:0003697 single-stranded DNA binding;GO:0140431 DNA-(abasic site) binding;GO:0160129 protein-DNA covalent cross-linking activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005657 replication fork", "go_biological_process": "GO:0097681 double-strand break repair via alternative nonhomologous end joining;GO:0006508 proteolysis;GO:0036297 interstrand cross-link repair;GO:0106300 protein-DNA covalent cross-linking repair", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q04471-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04487-1", "uniprot_id": "SHH3_YEAST", "mass": 22309.0, "length": 196, "protein_name": "Mitochondrial inner membrane protein SHH3", "gene_name": "SHH3", "organism": "Yeast", "refseq_name": "protein SHH3", "refseq_ac": "NP_013836", "gene_names_uniprotkb": "SHH3; YM9718.17C", "gene_names_refseq": "SHH3", "protein_names_uniprotkb": "Mitochondrial inner membrane protein SHH3; SDH3 homolog", "protein_names_refseq": "protein SHH3", "tax_id": 559292, "disease": "paraganglioma (Disease Ontology:DOID:0050773); pheochromocytoma/paraganglioma syndrome 3 (Disease Ontology:DOID:0061218); Carney-Stratakis syndrome (Disease Ontology:DOID:0080533); Leigh disease (Disease Ontology:DOID:3652); lung non-small cell carcinoma (Disease Ontology:DOID:3908); gastrointestinal stromal tumor (Disease Ontology:DOID:9253)", "pathway": " (sce:YMR118C); (R-SCE-71403)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "17322287;22152483;24374639;9169872", "class_list": "", "function": "Homolog of SDH3, but does not seem to be a stoichiometric subunit of either the succinate dehydrogenase (SDH) complex or the mitochondrial inner membrane translocase TIM22 complex., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZU1", "ec_number_list": "", "go_molecular_function": "GO:0009055 electron transfer activity;GO:0046872 metal ion binding;GO:0048038 quinone binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0045273 respiratory chain complex II (succinate dehydrogenase)", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0006121 mitochondrial electron transport, succinate to ubiquinone", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q04487-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04516-1", "uniprot_id": "AIM33_YEAST", "mass": 35764.0, "length": 312, "protein_name": "Uncharacterized oxidoreductase AIM33", "gene_name": "AIM33", "organism": "Yeast", "refseq_name": "cytochrome-b5 reductase", "refseq_ac": "NP_013623", "gene_names_uniprotkb": "AIM33", "gene_names_refseq": "AIM33", "protein_names_uniprotkb": "Uncharacterized oxidoreductase AIM33; 1.-.-.-; Altered inheritance of mitochondria protein 33", "protein_names_refseq": "cytochrome-b5 reductase", "tax_id": 559292, "disease": "estrogen-receptor negative breast cancer (Disease Ontology:DOID:0060076); methemoglobinemia (Disease Ontology:DOID:10783); breast cancer (Disease Ontology:DOID:1612)", "pathway": " (sce:YML087C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "16847258;19300474;24374639;9169872", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0J6", "ec_number_list": "", "go_molecular_function": "GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006696 ergosterol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q04516-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04533-1", "uniprot_id": "METX_YEAST", "mass": 74313.0, "length": 649, "protein_name": "Putative cystathionine gamma-synthase YML082W", "gene_name": "", "organism": "Yeast", "refseq_name": "putative cystathionine gamma-synthase", "refseq_ac": "NP_013628", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Putative cystathionine gamma-synthase YML082W; 2.5.1.48; O-succinylhomoserine (thiol)-lyase", "protein_names_refseq": "putative cystathionine gamma-synthase", "tax_id": 559292, "disease": "", "pathway": " (sce:YML082W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562106;18407956;24374639;33491328;9169872", "class_list": "", "function": "Catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma-replacement reaction. In the absence of thiol, catalyzes gamma-elimination to form 2-oxobutanoate, succinate and ammonia (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0K0", "ec_number_list": "2.5.1.48", "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0003962 cystathionine gamma-synthase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0009086 methionine biosynthetic process;GO:0019346 transsulfuration", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q04533-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04545-1", "uniprot_id": "TDA9_YEAST", "mass": 141465.0, "length": 1251, "protein_name": "Probable transcription factor TDA9", "gene_name": "TDA9", "organism": "Yeast", "refseq_name": "Tda9p", "refseq_ac": "NP_013630", "gene_names_uniprotkb": "TDA9", "gene_names_refseq": "AAF1; TDA9", "protein_names_uniprotkb": "Probable transcription factor TDA9; Topoisomerase I damage affected protein 9", "protein_names_refseq": "Tda9p", "tax_id": 559292, "disease": "", "pathway": " (sce:YML081W)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "14562095;14562106;15665377;17330950;18407956;19111667;19779198;19795423;19823750;21173034;23749301;24374639;32597660;33229814;33481703;33491328;9169872", "class_list": "", "function": "DNA-binding protein that acts probably as a transcription factor., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6W0K2;Q03621", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0019413 acetate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "Q04545-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04562-1", "uniprot_id": "TMN2_YEAST", "mass": 76347.0, "length": 672, "protein_name": "Transmembrane 9 superfamily member 2", "gene_name": "TMN2", "organism": "Yeast", "refseq_name": "Tmn2p", "refseq_ac": "NP_010392", "gene_names_uniprotkb": "TMN2", "gene_names_refseq": "TMN2", "protein_names_uniprotkb": "Transmembrane 9 superfamily member 2", "protein_names_refseq": "Tmn2p", "tax_id": 559292, "disease": "acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (sce:YDR107C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "16847258;18178563;20681974;24374639;9169867", "class_list": "", "function": "With EMP70 and TMN3, plays a critical role in the late stages of a nutrient-controlled pathway notably regulating FLO11 gene expression. Acts downstream of RAS2 and TOR. Essential for cell adhesion and filamentous growth. May play a role as effector of cellular copper homeostasis., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS93", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005768 endosome;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0007034 vacuolar transport;GO:0006811 monoatomic ion transport;GO:0006878 intracellular copper ion homeostasis;GO:0072657 protein localization to membrane;GO:0001403 invasive growth in response to glucose limitation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q04562-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04585-1", "uniprot_id": "YDR09_YEAST", "mass": 79161.0, "length": 715, "protein_name": "D-ribulokinase YDR109C", "gene_name": "", "organism": "Yeast", "refseq_name": "putative phosphotransferase", "refseq_ac": "NP_010394", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "D-ribulokinase YDR109C; 2.7.1.47", "protein_names_refseq": "putative phosphotransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR109C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "17563356;18407956;24374639;27909055;33481703;33491328;9169867", "class_list": "", "function": "Catalyzes ATP-dependent phosphorylation of D-ribulose at C-5 to form D-ribulose 5-phosphate. Postulated to function in a metabolite repair mechanism by preventing toxic accumulation of free D-ribulose formed by non-specific phosphatase activities. Alternatively, may play a role in regulating D-ribulose 5-phosphate recycling in the pentose phosphate pathway., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS95", "ec_number_list": "2.7.1.47", "go_molecular_function": "GO:0019150 D-ribulokinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0019321 pentose metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q04585-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04598-1", "uniprot_id": "RM34_YEAST", "mass": 12030.0, "length": 105, "protein_name": "Large ribosomal subunit protein bL34m", "gene_name": "YD9727.10", "organism": "Yeast", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "YD9727.10", "gene_names_refseq": "", "protein_names_uniprotkb": "Large ribosomal subunit protein bL34m; 54S ribosomal protein L34, mitochondrial; L34mt", "protein_names_refseq": "", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR115W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562095;14562106;17322287;24374639;24675956;25609543;9169867", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSA0", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q04598-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04599-1", "uniprot_id": "RM01_YEAST", "mass": 30996.0, "length": 285, "protein_name": "Large ribosomal subunit protein uL1m", "gene_name": "MRPL1", "organism": "Yeast", "refseq_name": "mitochondrial 54S ribosomal protein uL1m MRPL1", "refseq_ac": "NP_010401", "gene_names_uniprotkb": "MRPL1; YD9727.11C", "gene_names_refseq": "MRPL1; uL1m", "protein_names_uniprotkb": "Large ribosomal subunit protein uL1m; 54S ribosomal protein L1, mitochondrial", "protein_names_refseq": "mitochondrial 54S ribosomal protein uL1m MRPL1", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR116C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "12392552;14562095;14562106;14576278;17322287;21126336;24374639;24675956;25609543;33491328;9169867", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSA1", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006417 regulation of translation;GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q04599-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04600-1", "uniprot_id": "TMA64_YEAST", "mass": 63992.0, "length": 565, "protein_name": "Translation machinery-associated protein 64", "gene_name": "TMA64", "organism": "Yeast", "refseq_name": "Tma64p", "refseq_ac": "NP_010402", "gene_names_uniprotkb": "TMA64", "gene_names_refseq": "TMA64", "protein_names_uniprotkb": "Translation machinery-associated protein 64", "protein_names_refseq": "Tma64p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR117C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10093218;14562106;16702403;19795423;19823750;24374639;33491328;9169867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSA2", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0003743 translation initiation factor activity", "go_cellular_component": "", "go_biological_process": "GO:0006364 rRNA processing;GO:0001731 formation of translation preinitiation complex", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q04600-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04602-1", "uniprot_id": "VBA4_YEAST", "mass": 85683.0, "length": 768, "protein_name": "Vacuolar basic amino acid transporter 4", "gene_name": "VBA4", "organism": "Yeast", "refseq_name": "Vba4p", "refseq_ac": "NP_010404", "gene_names_uniprotkb": "VBA4", "gene_names_refseq": "VBA4", "protein_names_uniprotkb": "Vacuolar basic amino acid transporter 4", "protein_names_refseq": "Vba4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR119W)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "14562095;15572352;16847258;17330950;17563356;18407956;19001347;19779198;19795423;19823750;20702584;21126336;21177495;22218487;23749301;24374639;32597660;33481703;33491328;9169867", "class_list": "", "function": "Transporter required for vacuolar uptake of basic amino acids., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 2, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 24, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VSA4", "ec_number_list": "", "go_molecular_function": "GO:0015174 basic amino acid transmembrane transporter activity", "go_cellular_component": "GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0015802 basic amino acid transport;GO:0055085 transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "Q04602-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04623-1", "uniprot_id": "ECM18_YEAST", "mass": 53185.0, "length": 453, "protein_name": "Protein ECM18", "gene_name": "ECM18", "organism": "Yeast", "refseq_name": "alpha/beta hydrolase family protein", "refseq_ac": "NP_010410", "gene_names_uniprotkb": "ECM18; YD9727.20C", "gene_names_refseq": "ECM18", "protein_names_uniprotkb": "Protein ECM18; 2.3.1.-; Extracellular mutant protein 18", "protein_names_refseq": "alpha/beta hydrolase family protein", "tax_id": 559292, "disease": "Chanarin-Dorfman syndrome (Disease Ontology:DOID:0050729); autosomal recessive congenital ichthyosis 1 (Disease Ontology:DOID:0060656); colon adenocarcinoma (Disease Ontology:DOID:234); obesity (Disease Ontology:DOID:9970)", "pathway": " (sce:YDR125C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562095;14562106;24374639;9169867;9335584", "class_list": "", "function": "May be involved in cell wall organization and biogenesis., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSB1", "ec_number_list": "", "go_molecular_function": "GO:0042171 lysophosphatidic acid acyltransferase activity;GO:0004623 phospholipase A2 activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006654 phosphatidic acid biosynthetic process;GO:0055088 lipid homeostasis;GO:0071555 cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q04623-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04658-1", "uniprot_id": "SMA2_YEAST", "mass": 40872.0, "length": 369, "protein_name": "Spore membrane assembly protein 2", "gene_name": "SMA2", "organism": "Yeast", "refseq_name": "Sma2p", "refseq_ac": "NP_013645", "gene_names_uniprotkb": "SMA2", "gene_names_refseq": "SMA2", "protein_names_uniprotkb": "Spore membrane assembly protein 2", "protein_names_refseq": "Sma2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YML066C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "11470404;12432101;16847258;17298976;17322287;24374639;33491328;9169872", "class_list": "", "function": "Involved in spore and ascus formation. Required for the efficient assembly of the precursors of the prospore membrane to a continuous prospore membrane., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZA7", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0000329 fungal-type vacuole membrane;GO:0000324 fungal-type vacuole;GO:0005628 prospore membrane", "go_biological_process": "GO:0032120 ascospore-type prospore membrane formation;GO:0070583 spore membrane bending pathway", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q04658-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04675-1", "uniprot_id": "SEN15_YEAST", "mass": 14890.0, "length": 128, "protein_name": "tRNA-splicing endonuclease subunit SEN15", "gene_name": "SEN15", "organism": "Yeast", "refseq_name": "Sen15p", "refseq_ac": "NP_013775", "gene_names_uniprotkb": "SEN15; YM9796.12", "gene_names_refseq": "SEN15", "protein_names_uniprotkb": "tRNA-splicing endonuclease subunit SEN15; Splicing endonuclease of 15 kDa; tRNA-intron endonuclease SEN15", "protein_names_refseq": "Sen15p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR059W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "12925762;24374639;9169872;9200603", "class_list": "", "function": "Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZN3", "ec_number_list": "", "go_molecular_function": "GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0012505 endomembrane system;GO:0000214 tRNA-intron endonuclease complex", "go_biological_process": "GO:0000379 tRNA-type intron splice site recognition and cleavage", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q04675-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04697-1", "uniprot_id": "GSF2_YEAST", "mass": 45870.0, "length": 403, "protein_name": "Glucose-signaling factor 2", "gene_name": "GSF2", "organism": "Yeast", "refseq_name": "Gsf2p", "refseq_ac": "NP_013664", "gene_names_uniprotkb": "GSF2; ECM6; EFF2; YM9827.04", "gene_names_refseq": "ECM6; GSF2", "protein_names_uniprotkb": "Glucose-signaling factor 2; Extracellular mutant protein 6", "protein_names_refseq": "Gsf2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YML048W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "10377429;14562095;14562106;17322287;24374639;33481703;33491328;9169872;9335584;9335593", "class_list": "", "function": "May be involved in the secretion of hexose transporters from the endoplasmic reticulum. Involved in secretion of GAL2 and HXT1., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 2, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VZC7", "ec_number_list": "", "go_molecular_function": "GO:0051082 unfolded protein binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005741 mitochondrial outer membrane;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006457 protein folding;GO:0034394 protein localization to cell surface", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q04697-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04706-1", "uniprot_id": "YM11A_YEAST", "mass": 49122.0, "length": 440, "protein_name": "Transposon Ty1-ML1 Gag polyprotein", "gene_name": "TY1A-ML1", "organism": "Yeast", "refseq_name": "gag protein", "refseq_ac": "NP_058176", "gene_names_uniprotkb": "TY1A-ML1; YM9827.07; YMLWTy1-1 GAG", "gene_names_refseq": "", "protein_names_uniprotkb": "Transposon Ty1-ML1 Gag polyprotein; Gag-p45; Gag-p49; TY1A; TYA; Transposon Ty1 protein A; p54; p58", "protein_names_refseq": "gag protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YML045W-A)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "11884596;16093660;24374639;9169872;9582191", "class_list": "", "function": "Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA also has nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VZD1", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0075523 viral translational frameshifting", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q04706-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04734-1", "uniprot_id": "PALI_YEAST", "mass": 26697.0, "length": 239, "protein_name": "pH-response regulator protein palI/RIM9", "gene_name": "RIM9", "organism": "Yeast", "refseq_name": "Rim9p", "refseq_ac": "NP_013779", "gene_names_uniprotkb": "RIM9; YM9916.02", "gene_names_refseq": "RIM9", "protein_names_uniprotkb": "pH-response regulator protein palI/RIM9; Regulator of IME2 protein 9", "protein_names_refseq": "Rim9p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR063W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "16847258;23749301;24374639;33491328;8358819;9017390;9169872", "class_list": "", "function": "Required for the proteolytic cleavage of the transcriptional repressor RIM101 in response to alkaline ambient pH, which is necessary for sporulation and invasive growth., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZN7", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0035838 growing cell tip;GO:0005886 plasma membrane;GO:0032153 cell division site;GO:0000328 fungal-type vacuole lumen", "go_biological_process": "GO:0030437 ascospore formation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q04734-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04740-1", "uniprot_id": "RNH1_YEAST", "mass": 39431.0, "length": 348, "protein_name": "Ribonuclease H", "gene_name": "RNH1", "organism": "Yeast", "refseq_name": "RNA-DNA hybrid ribonuclease", "refseq_ac": "NP_013961", "gene_names_uniprotkb": "RNH1; YM9959.16", "gene_names_refseq": "RNH1", "protein_names_uniprotkb": "Ribonuclease H; 3.1.26.4; RNase H", "protein_names_refseq": "RNA-DNA hybrid ribonuclease", "tax_id": 559292, "disease": "autosomal recessive progressive external ophthalmoplegia with mitochondrial DNA deletions 2 (Disease Ontology:DOID:0111515)", "pathway": " (sce:YMR234W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10448044;14562106;1650910;24374639;9169872", "class_list": "", "function": "Endonuclease that specifically degrades the RNA of RNA-DNA hybrids., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W060", "ec_number_list": "", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0003676 nucleic acid binding;GO:0004523 RNA-DNA hybrid ribonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0043137 DNA replication, removal of RNA primer;GO:0006401 RNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q04740-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04751-1", "uniprot_id": "NAA40_YEAST", "mass": 32334.0, "length": 285, "protein_name": "N-alpha-acetyltransferase 40", "gene_name": "NAT4", "organism": "Yeast", "refseq_name": "N-terminal L-serine N(alpha)-acetyltransferase NatD", "refseq_ac": "NP_013785", "gene_names_uniprotkb": "NAT4; YM9916.08", "gene_names_refseq": "NAA40; NAT4", "protein_names_uniprotkb": "N-alpha-acetyltransferase 40; 2.3.1.257; Histone-specific N-acetyltransferase NAT4", "protein_names_refseq": "N-terminal L-serine N(alpha)-acetyltransferase NatD", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR069W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "12915400;14562095;17322287;18407956;21126336;24374639;32597660;33481703;33491328;9169872", "class_list": "", "function": "N-alpha-acetyltransferase that specifically mediates the acetylation of the N-terminal residues of histones H4 and H2A., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZP3", "ec_number_list": "2.3.1.257", "go_molecular_function": "GO:0010485 histone H4 acetyltransferase activity;GO:0043998 histone H2A acetyltransferase activity;GO:1990189 protein N-terminal-serine acetyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0031507 heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q04751-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04767-1", "uniprot_id": "TVP18_YEAST", "mass": 18693.0, "length": 167, "protein_name": "Golgi apparatus membrane protein TVP18", "gene_name": "TVP18", "organism": "Yeast", "refseq_name": "Tvp18p", "refseq_ac": "NP_013787", "gene_names_uniprotkb": "TVP18; YM9916.10C", "gene_names_refseq": "TVP18", "protein_names_uniprotkb": "Golgi apparatus membrane protein TVP18; TLG2 compartment vesicle protein of 18 kDa", "protein_names_refseq": "Tvp18p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR071C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "14562095;16107716;17178117;17322287;17330950;18407956;19779198;23749301;24374639;24909858;33481703;33491328;9169872", "class_list": "", "function": "Golgi membrane protein involved in vesicular trafficking., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VZP5", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0016192 vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q04767-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04772-1", "uniprot_id": "IRC21_YEAST", "mass": 23182.0, "length": 201, "protein_name": "Increased recombination centers protein 21", "gene_name": "IRC21", "organism": "Yeast", "refseq_name": "Irc21p", "refseq_ac": "NP_013789", "gene_names_uniprotkb": "IRC21; YM9916.12C", "gene_names_refseq": "IRC21", "protein_names_uniprotkb": "Increased recombination centers protein 21", "protein_names_refseq": "Irc21p", "tax_id": 559292, "disease": "type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (sce:YMR073C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562106;16121259;17322287;18085829;24374639;33229814;33491328;9169872", "class_list": "", "function": "Involved in resistance to carboplatin and cisplatin. Is probably involved in a pathway contributing to genomic integrity., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 5, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 5, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 5, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "D6VZP7", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006974 DNA damage response;GO:0009410 response to xenobiotic stimulus", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q04772-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04792-1", "uniprot_id": "DCE_YEAST", "mass": 65990.0, "length": 585, "protein_name": "Glutamate decarboxylase", "gene_name": "GAD1", "organism": "Yeast", "refseq_name": "glutamate decarboxylase GAD1", "refseq_ac": "NP_013976", "gene_names_uniprotkb": "GAD1; YM9920.04", "gene_names_refseq": "GAD1", "protein_names_uniprotkb": "Glutamate decarboxylase; 4.1.1.15; GAD", "protein_names_refseq": "glutamate decarboxylase GAD1", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR250W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562106;18407956;24374639;33491328;9169872", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W076", "ec_number_list": "4.1.1.15", "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0004351 glutamate decarboxylase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0034599 cellular response to oxidative stress;GO:0006538 L-glutamate catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q04792-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04806-1", "uniprot_id": "GSTO3_YEAST", "mass": 42403.0, "length": 366, "protein_name": "Glutathione S-transferase omega-like 3", "gene_name": "GTO3", "organism": "Yeast", "refseq_name": "omega-class glutathione transferase", "refseq_ac": "NP_013977", "gene_names_uniprotkb": "GTO3; YM9920.05", "gene_names_refseq": "GTO3", "protein_names_uniprotkb": "Glutathione S-transferase omega-like 3; 2.5.1.18", "protein_names_refseq": "omega-class glutathione transferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR251W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "16709151;16936141;17322287;24374639;9169872", "class_list": "", "function": "Active as '1-Cys' thiol transferase against beta-hydroxyethyl disulfide (HED), as dehydroascorbate reductase and as dimethylarsinic acid reductase, while not active against the standard GST substrate 1-chloro-2,4-dinitrobenzene (CDNB)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W077", "ec_number_list": "1.11.1.9;2.5.1.18;1.8.5.1", "go_molecular_function": "GO:0004364 glutathione transferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006749 glutathione metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q04806-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04894-1", "uniprot_id": "ADH6_YEAST", "mass": 39618.0, "length": 360, "protein_name": "NADP-dependent alcohol dehydrogenase 6", "gene_name": "ADH6", "organism": "Yeast", "refseq_name": "NADP-dependent alcohol dehydrogenase", "refseq_ac": "NP_014051", "gene_names_uniprotkb": "ADH6; YM9924.10C", "gene_names_refseq": "ADH6; ADHVI", "protein_names_uniprotkb": "NADP-dependent alcohol dehydrogenase 6; 1.1.1.2; 1.6.-.-; NADP-dependent alcohol dehydrogenase VI; S-nitroso-CoA reductase; ScADHVI; ScorR", "protein_names_refseq": "NADP-dependent alcohol dehydrogenase", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR318C)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "11742541;12554944;12604208;14562095;14562106;15289102;15665377;16652391;18407956;19779198;20702584;21126336;23749301;24374639;25512491;33481703;33491328;9169872", "class_list": "", "function": "NADP-dependent, medium-chain alcohol dehydrogenase with a broad substrate specificity (PubMed:11742541). Aldehydes exhibited 50-12000 times higher catalytic efficiency than the corresponding alcohols, therefore the major function of the enzyme is as an aldehyde reductase (PubMed:11742541). The enzyme is active towards aromatic and aliphatic (linear and branched-chain) aldehydes (PubMed:11742541). The enzyme is very active towards aromatic aldehydes, such as cinnamaldehyde, benzaldehyde and substituted benzaldehydes, such as veratraldehyde and panisaldehyde (PubMed:11742541). It exhibits low activity towards substituted cinnamaldehydes, such as coniferaldehyde and sinapaldehyde (PubMed:11742541). The enzyme has no activity with ketones, such as acetone or cyclohexanone (PubMed:11742541). For the reverse reaction, linear and branched-chain primary alcohols are substrates, whereas very low activity is found with secondary alcohols, such as butan-2-ol (PubMed:11742541). The enzyme may be physiologically involved in several steps of the lignin degradation pathway, initiated by other microorganisms, in the synthesis of fusel alcohols, products derived from the aminoacidic metabolism, and in the homeostasis of NADP(H) (PubMed:12604208). Has the ability to reduce 5-hydroxymethyl furfural (HMF), a furan derivative which is formed during the hydrolysis of lignocellulosic materials, to 5-hydroxymethylfurfuryl alcohol, thereby alleviating the inhibition of the fermentation of lignocellulose hydrolysates by HMF during fuel ethanol production (PubMed:16652391). Also acts as an inhibitor of protein S-nitrosylation by mediating degradation of S-nitroso-coenzyme A (S-nitroso-CoA), a cofactor required to S-nitrosylate proteins (PubMed:25512491)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0E6", "ec_number_list": "1.1.1.2;1.6.-.-;1.1.1.265;1.1.1.283", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0008106 alcohol dehydrogenase (NADP+) activity;GO:0033833 hydroxymethylfurfural reductase (NADH) activity;GO:0033845 hydroxymethylfurfural reductase (NADPH) activity;GO:0052675 3-methylbutanal reductase (NADPH) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006066 alcohol metabolic process;GO:0006081 aldehyde metabolic process;GO:0033859 furaldehyde metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "Q04894-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04895-1", "uniprot_id": "DAL4_YEAST", "mass": 71756.0, "length": 635, "protein_name": "Allantoin permease", "gene_name": "DAL4", "organism": "Yeast", "refseq_name": "allantoin permease", "refseq_ac": "NP_012294", "gene_names_uniprotkb": "DAL4", "gene_names_refseq": "DAL4", "protein_names_uniprotkb": "Allantoin permease; Allantoin transport protein", "protein_names_refseq": "allantoin permease", "tax_id": 559292, "disease": "", "pathway": " (sce:YIR028W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "1293888;16847258;24374639;9169870", "class_list": "", "function": "Transport of allantoin., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVV9", "ec_number_list": "", "go_molecular_function": "GO:0015205 nucleobase transmembrane transporter activity;GO:0005274 allantoin:proton symporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0015851 nucleobase transport;GO:0000256 allantoin catabolic process;GO:0006144 purine nucleobase metabolic process;GO:0015720 allantoin transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q04895-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04902-1", "uniprot_id": "SNO4_YEAST", "mass": 26040.0, "length": 237, "protein_name": "Probable glutathione-independent glyoxalase SNO4", "gene_name": "SNO4", "organism": "Yeast", "refseq_name": "glutathione-independent methylglyoxalase family protein", "refseq_ac": "NP_014055", "gene_names_uniprotkb": "SNO4; HSP34; YM9924.14C", "gene_names_refseq": "HSP34; SNO4", "protein_names_uniprotkb": "Probable glutathione-independent glyoxalase SNO4; 4.2.1.130; Glyoxalase 3 homolog 4; Heat shock protein 34; SNZ proximal open reading frame 4", "protein_names_refseq": "glutathione-independent methylglyoxalase family protein", "tax_id": 559292, "disease": "Parkinson's disease (Disease Ontology:DOID:14330); cancer (Disease Ontology:DOID:162)", "pathway": " (sce:YMR322C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14566057;14745011;24374639;24706893;9169872", "class_list": "", "function": "Catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step. May play a role in detoxifying endogenously produced glyoxals. Involved in protection against reactive oxygen species (ROS) (By similarity). Important for viability in stationary phase. May negatively regulate TORC1 in response to nutrient limitation (PubMed:24706893)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0E9", "ec_number_list": "4.2.1.130", "go_molecular_function": "GO:0019172 glyoxalase III activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0000932 P-body", "go_biological_process": "GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione;GO:0031669 cellular response to nutrient levels", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q04902-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04930-1", "uniprot_id": "CRF1_YEAST", "mass": 51697.0, "length": 467, "protein_name": "Transcription factor CRF1", "gene_name": "CRF1", "organism": "Yeast", "refseq_name": "Crf1p", "refseq_ac": "NP_010509", "gene_names_uniprotkb": "CRF1; YD9934.08", "gene_names_refseq": "CRF1", "protein_names_uniprotkb": "Transcription factor CRF1; Corepressor with FHL1 protein 1", "protein_names_refseq": "Crf1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR223W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14574415;14966276;15620355;24374639;33491328;8885406;9169867", "class_list": "", "function": "Transcription factor, corepressor with FHL1 of ribosomal protein genes. May be involved in the blocking of the spread of silencing., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSK5", "ec_number_list": "", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0003714 transcription corepressor activity;GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000785 chromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0010688 negative regulation of ribosomal protein gene transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q04930-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04949-1", "uniprot_id": "DYN3_YEAST", "mass": 36825.0, "length": 312, "protein_name": "Cytoplasmic dynein intermediate light chain DYN3", "gene_name": "DYN3", "organism": "Yeast", "refseq_name": "dynein light intermediate chain", "refseq_ac": "NP_014028", "gene_names_uniprotkb": "DYN3; YM9952.01C", "gene_names_refseq": "DYN3", "protein_names_uniprotkb": "Cytoplasmic dynein intermediate light chain DYN3; Dynein protein 3", "protein_names_refseq": "dynein light intermediate chain", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR299C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562095;14562106;15642746;19779198;24374639;33491328;9169872", "class_list": "", "function": "Component of the cytoplasmic dynein which acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play an important role in the proper orientation of the mitotic spindle into the budding daughter cell yeast. Probably required for normal progression of the cell cycle., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0C6;Q03592", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005881 cytoplasmic microtubule;GO:0005868 cytoplasmic dynein complex", "go_biological_process": "GO:0000132 establishment of mitotic spindle orientation;GO:0040001 establishment of mitotic spindle localization;GO:0030473 nuclear migration along microtubule", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q04949-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04952-1", "uniprot_id": "FKS3_YEAST", "mass": 207483.0, "length": 1785, "protein_name": "1,3-beta-glucan synthase component FKS3", "gene_name": "FKS3", "organism": "Yeast", "refseq_name": "putative 1,3-beta-D-glucan synthase", "refseq_ac": "NP_014036", "gene_names_uniprotkb": "FKS3; YM9952.08", "gene_names_refseq": "FKS3", "protein_names_uniprotkb": "1,3-beta-glucan synthase component FKS3; 1,3-beta-D-glucan-UDP glucosyltransferase; 2.4.1.34; FK506 sensitivity protein 3", "protein_names_refseq": "putative 1,3-beta-D-glucan synthase", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR306W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14576278;17158736;19756047;21126336;24374639;33491328;9169872", "class_list": "", "function": "Required for spore wall assembly., [UniProtKB, PubMed]", "predicted_glycosites": 8, "predicted_n_glycosites": 8, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "D6W0D3", "ec_number_list": "2.4.1.34", "go_molecular_function": "GO:0003843 1,3-beta-D-glucan synthase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0031160 spore wall;GO:0000148 1,3-beta-D-glucan synthase complex", "go_biological_process": "GO:0006075 (1->3)-beta-D-glucan biosynthetic process;GO:0030476 ascospore wall assembly;GO:0051278 fungal-type cell wall polysaccharide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q04952-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05015-1", "uniprot_id": "FSH2_YEAST", "mass": 24534.0, "length": 223, "protein_name": "Family of serine hydrolases 2", "gene_name": "FSH2", "organism": "Yeast", "refseq_name": "putative serine hydrolase", "refseq_ac": "NP_013949", "gene_names_uniprotkb": "FSH2; YM9959.04C", "gene_names_refseq": "FSH2", "protein_names_uniprotkb": "Family of serine hydrolases 2; 3.1.-.-", "protein_names_refseq": "putative serine hydrolase", "tax_id": 559292, "disease": "ovarian cancer (Disease Ontology:DOID:2394)", "pathway": " (sce:YMR222C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562095;14562106;14645503;24374639;9169872", "class_list": "", "function": "Serine hydrolase of unknown specificity., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W047", "ec_number_list": "", "go_molecular_function": "GO:0016787 hydrolase activity;GO:0052689 carboxylic ester hydrolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q05015-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05024-1", "uniprot_id": "TRI1_YEAST", "mass": 26471.0, "length": 226, "protein_name": "Protein TRI1", "gene_name": "TRI1", "organism": "Yeast", "refseq_name": "Tri1p", "refseq_ac": "NP_013960", "gene_names_uniprotkb": "TRI1; YM9959.15", "gene_names_refseq": "TRI1", "protein_names_uniprotkb": "Protein TRI1", "protein_names_refseq": "Tri1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR233W)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "14562095;14562106;17322287;17603101;18407956;19779198;20702584;21126336;23749301;24374639;24909858;32597660;33481703;33491328;33502312;9169872", "class_list": "", "function": "May be involved in transcription regulation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W059", "ec_number_list": "", "go_molecular_function": "GO:0001165 RNA polymerase I cis-regulatory region sequence-specific DNA binding;GO:0001181 RNA polymerase I general transcription initiation factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0000500 RNA polymerase I upstream activating factor complex", "go_biological_process": "GO:0006361 transcription initiation at RNA polymerase I promoter;GO:0042790 nucleolar large rRNA transcription by RNA polymerase I", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q05024-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05043-1", "uniprot_id": "RSF1_YEAST", "mass": 43460.0, "length": 376, "protein_name": "Respiration factor 1", "gene_name": "RSF1", "organism": "Yeast", "refseq_name": "Rsf1p", "refseq_ac": "NP_013743", "gene_names_uniprotkb": "RSF1; YM9973.03", "gene_names_refseq": "RSF1", "protein_names_uniprotkb": "Respiration factor 1", "protein_names_refseq": "Rsf1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR030W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "12734673;14562095;16464826;17003135;17322287;18407956;19779198;23749301;24374639;33491328;9169872", "class_list": "", "function": "Mitochondrial and nuclear transcriptional activator required for respiratory growth., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZK4", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion", "go_biological_process": "GO:0006366 transcription by RNA polymerase II;GO:0009060 aerobic respiration;GO:0006390 mitochondrial transcription", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q05043-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05131-1", "uniprot_id": "RCH1_YEAST", "mass": 48375.0, "length": 434, "protein_name": "Solute carrier RCH1", "gene_name": "RCH1", "organism": "Yeast", "refseq_name": "Rch1p", "refseq_ac": "NP_013748", "gene_names_uniprotkb": "RCH1; YM9973.08C", "gene_names_refseq": "RCH1", "protein_names_uniprotkb": "Solute carrier RCH1; Regulator of calcium homeostasis 1", "protein_names_refseq": "Rch1p", "tax_id": 559292, "disease": "osteoporosis (Disease Ontology:DOID:11476); amelogenesis imperfecta (Disease Ontology:DOID:2187); syndrome (Disease Ontology:DOID:225); osteochondrodysplasia (Disease Ontology:DOID:2256)", "pathway": " (sce:YMR034C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "16847258;17322287;19779198;24374639;26832117;32597660;33491328;9169872", "class_list": "", "function": "Solute carrier protein that negatively regulates the cytosolic calcium homeostasis in response to high levels of extracellular calcium., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZK9", "ec_number_list": "", "go_molecular_function": "GO:0008028 monocarboxylic acid transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:0005935 cellular bud neck", "go_biological_process": "GO:0006816 calcium ion transport;GO:0051481 negative regulation of cytosolic calcium ion concentration", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q05131-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05468-1", "uniprot_id": "RQC1_YEAST", "mass": 83426.0, "length": 723, "protein_name": "Ribosome quality control complex subunit 1", "gene_name": "RQC1", "organism": "Yeast", "refseq_name": "Rqc1p", "refseq_ac": "NP_010620", "gene_names_uniprotkb": "RQC1", "gene_names_refseq": "RQC1", "protein_names_uniprotkb": "Ribosome quality control complex subunit 1", "protein_names_refseq": "Rqc1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR333C); (R-SCE-9954709)", "pathway_count": 2, "publication_count": 21, "publication_id_list": "14562095;14562106;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;23178123;23479637;23749301;24374639;27129255;30516470;32597660;33481703;33491328;9169867", "class_list": "", "function": "Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation (PubMed:23178123, PubMed:27129255). Within the RQC complex, RQC1 is essential for the recruitment of CDC48 to incompletely synthesized nascent polypeptides that are ubiquitinated by RKR1/LTN1 (PubMed:23479637, PubMed:27129255)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSW5", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:1990112 RQC complex", "go_biological_process": "GO:0072344 rescue of stalled ribosome;GO:1990116 ribosome-associated ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "Q05468-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05473-1", "uniprot_id": "MRX8_YEAST", "mass": 35614.0, "length": 314, "protein_name": "MIOREX complex component 8", "gene_name": "MRX8", "organism": "Yeast", "refseq_name": "translation initiation/elongation factor MRX8", "refseq_ac": "NP_010623", "gene_names_uniprotkb": "MRX8", "gene_names_refseq": "MRX8", "protein_names_uniprotkb": "MIOREX complex component 8; Mitochondrial organization of gene expression protein 8", "protein_names_refseq": "translation initiation/elongation factor MRX8", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR336W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "15166219;24374639;25683707;9169867", "class_list": "", "function": "Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSW8", "ec_number_list": "", "go_molecular_function": "GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0019001 guanyl nucleotide binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0099617 matrix side of mitochondrial inner membrane", "go_biological_process": "GO:0070124 mitochondrial translational initiation;GO:0070125 mitochondrial translational elongation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q05473-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05498-1", "uniprot_id": "FCF1_YEAST", "mass": 21611.0, "length": 189, "protein_name": "rRNA-processing protein FCF1", "gene_name": "FCF1", "organism": "Yeast", "refseq_name": "rRNA-processing protein FCF1", "refseq_ac": "NP_010626", "gene_names_uniprotkb": "FCF1; D9651.9", "gene_names_refseq": "FCF1; UTP24", "protein_names_uniprotkb": "rRNA-processing protein FCF1; FAF1-copurifying factor 1", "protein_names_refseq": "rRNA-processing protein FCF1", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR339C); (R-SCE-6791226)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "16762320;17322287;24374639;9169867", "class_list": "", "function": "Essential protein involved in pre-rRNA processing and 40S ribosomal subunit assembly. Required for the early cleavage steps of 35S rRNA at the A(0), A(1), and A(2) sites., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSX1", "ec_number_list": "", "go_molecular_function": "GO:0004521 RNA endonuclease activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0032040 small-subunit processome", "go_biological_process": "GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0030490 maturation of SSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q05498-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05518-1", "uniprot_id": "PAL1_YEAST", "mass": 54996.0, "length": 499, "protein_name": "Protein PAL1", "gene_name": "PAL1", "organism": "Yeast", "refseq_name": "Pal1p", "refseq_ac": "NP_010635", "gene_names_uniprotkb": "PAL1", "gene_names_refseq": "PAL1", "protein_names_uniprotkb": "Protein PAL1; Pears and lemons protein 1", "protein_names_refseq": "Pal1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR348C)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "14562095;14562106;15665377;17322287;17330950;17563356;18407956;19684113;19779198;20702584;21126336;21177495;22106047;22190733;22218487;23749301;24374639;24909858;30516470;32597660;33481703;33491328;9169867", "class_list": "", "function": "Involved in the early step of endocytosis., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 70, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VSX8;Q66RD5", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0030479 actin cortical patch;GO:0005934 cellular bud tip", "go_biological_process": "GO:0006897 endocytosis", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "Q05518-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05543-1", "uniprot_id": "RT103_YEAST", "mass": 46488.0, "length": 409, "protein_name": "Regulator of Ty1 transposition protein 103", "gene_name": "RTT103", "organism": "Yeast", "refseq_name": "Rtt103p", "refseq_ac": "NP_010575", "gene_names_uniprotkb": "RTT103", "gene_names_refseq": "RTT103", "protein_names_uniprotkb": "Regulator of Ty1 transposition protein 103", "protein_names_refseq": "Rtt103p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR289C); (R-SCE-6807505)", "pathway_count": 2, "publication_count": 15, "publication_id_list": "11779788;14562095;14562106;15565157;17322287;18407956;19795423;19823750;21126336;23749301;24374639;32597660;33481703;33491328;9169867", "class_list": "", "function": "Involved in transcription termination by RNA polymerase II and in regulation of Ty1 transposition., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 16, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSR9", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0000993 RNA polymerase II complex binding;GO:1990269 RNA polymerase II C-terminal domain phosphoserine binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0035861 site of double-strand break", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0031124 mRNA 3'-end processing;GO:0010526 transposable element silencing", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q05543-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05584-1", "uniprot_id": "GLO2_YEAST", "mass": 31327.0, "length": 274, "protein_name": "Hydroxyacylglutathione hydrolase, cytoplasmic isozyme", "gene_name": "GLO2", "organism": "Yeast", "refseq_name": "hydroxyacylglutathione hydrolase GLO2", "refseq_ac": "NP_010558", "gene_names_uniprotkb": "GLO2; D9954.5", "gene_names_refseq": "GLO2", "protein_names_uniprotkb": "Hydroxyacylglutathione hydrolase, cytoplasmic isozyme; 3.1.2.6; Glx II; Glyoxalase II", "protein_names_refseq": "hydroxyacylglutathione hydrolase GLO2", "tax_id": 559292, "disease": "paroxysmal nonkinesigenic dyskinesia 1 (Disease Ontology:DOID:0090049)", "pathway": " (sce:YDR272W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10600466;14562106;17322287;18407956;21126336;22814378;23749301;24374639;33481703;33491328;9169867;9261170", "class_list": "", "function": "Thiolesterase that catalyzes the hydrolysis of S-D-lactoylglutathione to form glutathione and D-lactic acid. Involved in the metabolism of methylglyoxal, a toxic compound for yeast proliferation, by converting methylglyoxal to lactate via S-D-lactoylglutathione by sequential enzyme reactions catalyzed by glyoxalase I and glyoxalase II., [UniProtKB, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSQ4;E9P8T0", "ec_number_list": "3.1.2.6", "go_molecular_function": "GO:0004416 hydroxyacylglutathione hydrolase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q05584-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05610-1", "uniprot_id": "DON1_YEAST", "mass": 40162.0, "length": 365, "protein_name": "Donuts protein 1", "gene_name": "DON1", "organism": "Yeast", "refseq_name": "Don1p", "refseq_ac": "NP_010559", "gene_names_uniprotkb": "DON1; D9954.4", "gene_names_refseq": "DON1", "protein_names_uniprotkb": "Donuts protein 1", "protein_names_refseq": "Don1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR273W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10899120;11742972;11973299;17322287;24374639;33491328;9169867", "class_list": "", "function": "Involved in the pathway that organizes the prospore membrane (PSM) during sporulation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSQ5;Q66RE0", "ec_number_list": "", "go_molecular_function": "GO:0031624 ubiquitin conjugating enzyme binding;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005628 prospore membrane;GO:0070056 prospore membrane leading edge", "go_biological_process": "GO:0051301 cell division;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0030476 ascospore wall assembly", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q05610-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05648-1", "uniprot_id": "MRX10_YEAST", "mass": 47173.0, "length": 414, "protein_name": "MIOREX complex component 10", "gene_name": "MRX10", "organism": "Yeast", "refseq_name": "Mrx10p", "refseq_ac": "NP_010568", "gene_names_uniprotkb": "MRX10", "gene_names_refseq": "MRX10", "protein_names_uniprotkb": "MIOREX complex component 10; Mitochondrial organization of gene expression protein 10", "protein_names_refseq": "Mrx10p", "tax_id": 559292, "disease": "combined oxidative phosphorylation deficiency 11 (Disease Ontology:DOID:0111481)", "pathway": " (sce:YDR282C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "23022099;24374639;25683707;9169867", "class_list": "", "function": "Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSR2", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0070131 positive regulation of mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q05648-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05670-1", "uniprot_id": "FUS2_YEAST", "mass": 79037.0, "length": 677, "protein_name": "Nuclear fusion protein FUS2", "gene_name": "FUS2", "organism": "Yeast", "refseq_name": "Fus2p", "refseq_ac": "NP_013959", "gene_names_uniprotkb": "FUS2; YM9959.14", "gene_names_refseq": "FUS2", "protein_names_uniprotkb": "Nuclear fusion protein FUS2", "protein_names_refseq": "Fus2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR232W); (R-SCE-193648); (R-SCE-416482); (R-SCE-9013148)", "pathway_count": 4, "publication_count": 10, "publication_id_list": "17330950;18407956;19188495;22588722;24374639;33481703;33491328;35454186;7559752;9169872", "class_list": "", "function": "Promotes cell fusion during zygote formation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W058;Q05023", "ec_number_list": "", "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0043332 mating projection tip", "go_biological_process": "GO:0031991 regulation of actomyosin contractile ring contraction;GO:0032955 regulation of division septum assembly;GO:0000742 karyogamy involved in conjugation with cellular fusion;GO:0000747 conjugation with cellular fusion;GO:0000755 cytogamy", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q05670-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05672-1", "uniprot_id": "RBS1_YEAST", "mass": 51957.0, "length": 457, "protein_name": "RNA-binding suppressor of PAS kinase protein 1", "gene_name": "RBS1", "organism": "Yeast", "refseq_name": "Rbs1p", "refseq_ac": "NP_010092", "gene_names_uniprotkb": "RBS1; D1266", "gene_names_refseq": "RBS1", "protein_names_uniprotkb": "RNA-binding suppressor of PAS kinase protein 1", "protein_names_refseq": "Rbs1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL189W)", "pathway_count": 1, "publication_count": 21, "publication_id_list": "11875433;12844361;14562095;14562106;1656215;17287358;17563356;18407956;19779198;19795423;19823750;21177495;23749301;24374639;30516470;32597660;33481703;33491328;34965436;8533471;9169867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRG4;Q06896;Q07619;Q870H2", "ec_number_list": "", "go_molecular_function": "GO:0048027 mRNA 5'-UTR binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006012 galactose metabolic process;GO:1990115 RNA polymerase III assembly", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "Q05672-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05676-1", "uniprot_id": "SOM1_YEAST", "mass": 8416.0, "length": 74, "protein_name": "Protein SOM1, mitochondrial", "gene_name": "SOM1", "organism": "Yeast", "refseq_name": "Som1p", "refseq_ac": "NP_058154", "gene_names_uniprotkb": "SOM1; YEL059BC", "gene_names_refseq": "SOM1", "protein_names_uniprotkb": "Protein SOM1, mitochondrial; Mitochondrial inner membrane protease subunit SOM1", "protein_names_refseq": "Som1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YEL059C-A)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562106;15254042;17322287;24374639;33481703;8879245;9169868", "class_list": "", "function": "Non-catalytic component of the mitochondrial inner membrane peptidase (IMP) complex. IMP catalyzes the removal of signal peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. SOM1 facilitates cleavage of a subset of IMP substrates., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLJ1", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0042720 mitochondrial inner membrane peptidase complex;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0033108 mitochondrial respiratory chain complex assembly;GO:0006465 signal peptide processing", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q05676-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05777-1", "uniprot_id": "NCW2_YEAST", "mass": 25762.0, "length": 254, "protein_name": "Cell wall biogenesis protein NCW2", "gene_name": "NCW2", "organism": "Yeast", "refseq_name": "Ncw2p", "refseq_ac": "NP_013295", "gene_names_uniprotkb": "NCW2", "gene_names_refseq": "NCW2", "protein_names_uniprotkb": "Cell wall biogenesis protein NCW2; New cell wall protein 2", "protein_names_refseq": "Ncw2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR194C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10383953;10594829;11016834;14562106;24374639;27246500;9169871", "class_list": "", "function": "Cell wall biogenesis protein that participates in the organization of the beta-glucan assembly (PubMed:27246500). Involved in the mechanism responsible for cell tolerance to polyhexamethylene biguanide (PHMB), an antifungal agent (PubMed:27246500)., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VYJ7", "ec_number_list": "", "go_molecular_function": "GO:0005199 structural constituent of cell wall", "go_cellular_component": "GO:0005886 plasma membrane;GO:0000324 fungal-type vacuole;GO:0005935 cellular bud neck;GO:0009277 fungal-type cell wall;GO:0098552 side of membrane", "go_biological_process": "GO:0006033 chitin localization;GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q05777-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05778-1", "uniprot_id": "POC1_YEAST", "mass": 30695.0, "length": 276, "protein_name": "Proteasome chaperone 1", "gene_name": "PBA1", "organism": "Yeast", "refseq_name": "Pba1p", "refseq_ac": "NP_013300", "gene_names_uniprotkb": "PBA1; POC1", "gene_names_refseq": "PBA1; POC1", "protein_names_uniprotkb": "Proteasome chaperone 1; Proteasome biogenesis-associated protein 1", "protein_names_refseq": "Pba1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR199C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "12775844;14562095;14562106;17431397;17707236;18407956;21126336;23749301;24374639;32597660;33481703;33491328;9169871", "class_list": "", "function": "Involved in 20S proteasome assembly., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYK1", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0043248 proteasome assembly;GO:0080129 proteasome core complex assembly", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q05778-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05788-1", "uniprot_id": "PNPH_YEAST", "mass": 33755.0, "length": 311, "protein_name": "Purine nucleoside phosphorylase", "gene_name": "PNP1", "organism": "Yeast", "refseq_name": "purine-nucleoside phosphorylase", "refseq_ac": "NP_013310", "gene_names_uniprotkb": "PNP1; L8167.19", "gene_names_refseq": "PNP1", "protein_names_uniprotkb": "Purine nucleoside phosphorylase; 2.4.2.1; Inosine phosphorylase; Inosine-guanosine phosphorylase; PNP", "protein_names_refseq": "purine-nucleoside phosphorylase", "tax_id": 559292, "disease": "purine nucleoside phosphorylase deficiency (Disease Ontology:DOID:5813); purine-pyrimidine metabolic disorder (Disease Ontology:DOID:653)", "pathway": " (sce:YLR209C); (R-SCE-6798695); (R-SCE-74217); (R-SCE-74259); (R-SCE-9755088)", "pathway_count": 5, "publication_count": 7, "publication_id_list": "14562106;17322287;18407956;22814378;24374639;33491328;9169871", "class_list": "", "function": "The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine and inosine (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYL0", "ec_number_list": "2.7.1.40;5.4.2.11;2.7.1.1;4.2.1.24;3.6.4.13;2.4.1.1;3.4.23.25;3.6.4.10;5.3.1.9;5.1.3.-;5.2.1.8;1.11.1.6;3.5.4.6;2.7.1.11;2.7.1.2;1.1.1.42;3.4.25.1;3.6.4.6;3.6.5.-;2.7.11.24;3.6.4.12;5.4.2.2;1.11.1.24;2.7.4.6;2.4.1.186;1.1.1.205;2.7.1.35;3.4.19.12;2.4.2.7;5.4.2.7;2.3.2.26;2.7.11.23;2.4.2.1;2.7.1.59;3.5.4.5;3.4.11.-;3.3.2.10", "go_molecular_function": "GO:0004731 purine-nucleoside phosphorylase activity;GO:0047724 inosine nucleosidase activity;GO:0070635 nicotinamide riboside hydrolase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006148 inosine catabolic process;GO:0019358 nicotinate nucleotide salvage;GO:0046115 guanosine catabolic process;GO:0034355 NAD+ biosynthetic process via the salvage pathway", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q05788-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05790-1", "uniprot_id": "CRR1_YEAST", "mass": 47356.0, "length": 422, "protein_name": "Probable glycosidase CRR1", "gene_name": "CRR1", "organism": "Yeast", "refseq_name": "putative glycosylase", "refseq_ac": "NP_013314", "gene_names_uniprotkb": "CRR1", "gene_names_refseq": "CRR1", "protein_names_uniprotkb": "Probable glycosidase CRR1; 3.2.-.-; CRH-related protein 1", "protein_names_refseq": "putative glycosylase", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR213C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10757808;10922376;15470107;15886332;24374639;9169871", "class_list": "", "function": "Spore specific glycosidase involved in spore wall assembly during sporulation. May be involved in copper import., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYL4", "ec_number_list": "", "go_molecular_function": "GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0016757 glycosyltransferase activity;GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds", "go_cellular_component": "GO:0005576 extracellular region;GO:0000324 fungal-type vacuole;GO:0005619 ascospore wall;GO:0009277 fungal-type cell wall", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0006030 chitin metabolic process;GO:0030476 ascospore wall assembly;GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q05790-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05809-1", "uniprot_id": "COA4_YEAST", "mass": 11239.0, "length": 96, "protein_name": "Cytochrome oxidase assembly factor 4", "gene_name": "COA4", "organism": "Yeast", "refseq_name": "Coa4p", "refseq_ac": "NP_013319", "gene_names_uniprotkb": "COA4; CMC3", "gene_names_refseq": "CMC3; COA4", "protein_names_uniprotkb": "Cytochrome oxidase assembly factor 4; Cx9C motif-containing protein 3", "protein_names_refseq": "Coa4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR218C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562095;14562106;19703468;20624914;22984289;24374639;33491328;9169871", "class_list": "", "function": "Involved in cytochrome c oxidase assembly or stability., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYL8", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005743 mitochondrial inner membrane;GO:0005758 mitochondrial intermembrane space", "go_biological_process": "GO:0033108 mitochondrial respiratory chain complex assembly;GO:0033617 mitochondrial respiratory chain complex IV assembly", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q05809-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05827-1", "uniprot_id": "HOR7_YEAST", "mass": 5573.0, "length": 59, "protein_name": "Protein HOR7", "gene_name": "HOR7", "organism": "Yeast", "refseq_name": "Hor7p", "refseq_ac": "NP_013978", "gene_names_uniprotkb": "HOR7; YMR251BW", "gene_names_refseq": "HOR7", "protein_names_uniprotkb": "Protein HOR7; Protein A0.5", "protein_names_refseq": "Hor7p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR251W-A)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562106;24374639;7500933;9169872;9234669", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W078", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0007009 plasma membrane organization", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q05827-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05874-1", "uniprot_id": "EFM7_YEAST", "mass": 29633.0, "length": 261, "protein_name": "Protein N-terminal and lysine N-methyltransferase EFM7", "gene_name": "NNT1", "organism": "Yeast", "refseq_name": "S-adenosylmethionine-dependent methyltransferase", "refseq_ac": "NP_013387", "gene_names_uniprotkb": "NNT1; EFM7", "gene_names_refseq": "EFM7; NNT1", "protein_names_uniprotkb": "Protein N-terminal and lysine N-methyltransferase EFM7; 2.1.1.-; Elongation factor methyltransferase 7; Nicotinamide N-methyltransferase-like protein 1", "protein_names_refseq": "S-adenosylmethionine-dependent methyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR285W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "12736687;14562095;14562106;17322287;21858014;24374639;26545399;29183786;33491328;9169871", "class_list": "", "function": "S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha (TEF1 and TEF2), before also catalyzing the mono- and dimethylation of 'Lys-3' (PubMed:21858014, PubMed:26545399). May be involved in rDNA silencing and in lifespan determination (PubMed:12736687)., [UniProtKB, HAMAP, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYS9", "ec_number_list": "", "go_molecular_function": "GO:0071885 N-terminal protein N-methyltransferase activity;GO:0008276 protein methyltransferase activity;GO:0008757 S-adenosylmethionine-dependent methyltransferase activity;GO:0016279 protein-lysine N-methyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0032259 methylation;GO:0000183 rDNA heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q05874-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05892-1", "uniprot_id": "COQ11_YEAST", "mass": 31524.0, "length": 277, "protein_name": "MIOREX complex component 2", "gene_name": "COQ11", "organism": "Yeast", "refseq_name": "ubiquinone biosynthesis protein COQ11", "refseq_ac": "NP_013393", "gene_names_uniprotkb": "COQ11; MRX2", "gene_names_refseq": "COQ11; MRX2", "protein_names_uniprotkb": "MIOREX complex component 2; Mitochondrial organization of gene expression protein 2", "protein_names_refseq": "ubiquinone biosynthesis protein COQ11", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR290C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562095;14562106;16823961;24374639;25631044;25683707;9169871", "class_list": "", "function": "Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression (PubMed:25683707). Component of a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis (PubMed:25631044)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYT6", "ec_number_list": "", "go_molecular_function": "GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006744 ubiquinone biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q05892-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05905-1", "uniprot_id": "HRI1_YEAST", "mass": 27501.0, "length": 244, "protein_name": "Protein HRI1", "gene_name": "HRI1", "organism": "Yeast", "refseq_name": "Hri1p", "refseq_ac": "NP_013404", "gene_names_uniprotkb": "HRI1", "gene_names_refseq": "HRI1", "protein_names_uniprotkb": "Protein HRI1; HRR25-interacting protein 1", "protein_names_refseq": "Hri1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR301W)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "12518317;14562095;14562106;17322287;17330950;18407956;19779198;21460040;23749301;24374639;33481703;33491328;9169871", "class_list": "", "function": "Unknown. Non essential., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYU5", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006612 protein targeting to membrane", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q05905-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05926-1", "uniprot_id": "GLRX8_YEAST", "mass": 12519.0, "length": 109, "protein_name": "Glutaredoxin-8", "gene_name": "GRX8", "organism": "Yeast", "refseq_name": "glutathione-disulfide reductase GRX8", "refseq_ac": "NP_013468", "gene_names_uniprotkb": "GRX8", "gene_names_refseq": "GRX8", "protein_names_uniprotkb": "Glutaredoxin-8; Glutathione-dependent oxidoreductase 8", "protein_names_refseq": "glutathione-disulfide reductase GRX8", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR364W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562095;14562106;15575969;17322287;18400945;19166312;24374639;9169871", "class_list": "", "function": "Glutathione-dependent oxidoreductase with lower activity compared to the other members of the glutaredoxin family. The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ03", "ec_number_list": "", "go_molecular_function": "GO:0004362 glutathione-disulfide reductase (NADPH) activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q05926-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05937-1", "uniprot_id": "STP3_YEAST", "mass": 37718.0, "length": 343, "protein_name": "Zinc finger protein STP3", "gene_name": "STP3", "organism": "Yeast", "refseq_name": "Stp3p", "refseq_ac": "NP_013479", "gene_names_uniprotkb": "STP3", "gene_names_refseq": "STP3", "protein_names_uniprotkb": "Zinc finger protein STP3", "protein_names_refseq": "Stp3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR375W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562095;14562106;15665377;18407956;19779198;24374639;32597660;33481703;33491328;9169871", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ11", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q05937-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05955-1", "uniprot_id": "ADY4_YEAST", "mass": 57833.0, "length": 493, "protein_name": "Accumulates dyads protein 4", "gene_name": "ADY4", "organism": "Yeast", "refseq_name": "Ady4p", "refseq_ac": "NP_013328", "gene_names_uniprotkb": "ADY4; L8083.11", "gene_names_refseq": "ADY4", "protein_names_uniprotkb": "Accumulates dyads protein 4", "protein_names_refseq": "Ady4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR227C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "11470404;12796288;24374639;33491328;9169871", "class_list": "", "function": "Involved in the pathway that organizes the shaping and sizing of the prospore membrane (PSM) during sporulation. May be required to stabilize the outer plaque of the spindle pole body (SPB)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYM7", "ec_number_list": "", "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0035974 meiotic spindle pole body", "go_biological_process": "GO:0051301 cell division;GO:0030437 ascospore formation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q05955-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05998-1", "uniprot_id": "THI7_YEAST", "mass": 66904.0, "length": 598, "protein_name": "Thiamine transporter", "gene_name": "THI7", "organism": "Yeast", "refseq_name": "thiamine transporter THI7", "refseq_ac": "NP_013338", "gene_names_uniprotkb": "THI7; L8083.2; THI10", "gene_names_refseq": "THI10; THI7", "protein_names_uniprotkb": "Thiamine transporter", "protein_names_refseq": "thiamine transporter THI7", "tax_id": 559292, "disease": "megaloblastic anemia (Disease Ontology:DOID:13382)", "pathway": " (sce:YLR237W)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "14562106;16847258;18407956;19684113;19779198;19795423;19823750;21177495;23749301;24374639;32597660;33481703;33491328;9169871;9235906", "class_list": "", "function": "Responsible for intake of thiamine., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYN5;P87335", "ec_number_list": "", "go_molecular_function": "GO:0015205 nucleobase transmembrane transporter activity;GO:0015234 thiamine transmembrane transporter activity;GO:1903089 5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0015851 nucleobase transport;GO:0015888 thiamine transport;GO:1903088 5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q05998-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06001-1", "uniprot_id": "FAR10_YEAST", "mass": 54092.0, "length": 478, "protein_name": "Factor arrest protein 10", "gene_name": "FAR10", "organism": "Yeast", "refseq_name": "Far10p", "refseq_ac": "NP_013339", "gene_names_uniprotkb": "FAR10", "gene_names_refseq": "FAR10", "protein_names_uniprotkb": "Factor arrest protein 10", "protein_names_refseq": "Far10p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR238W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "12514182;12588993;17287358;21177495;23749301;24374639;32597660;33481703;33491328;9169871", "class_list": "", "function": "Participates in the control of the reentry into the cell cycle following pheromone treatment., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYN6", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0010506 regulation of autophagy;GO:0071444 cellular response to pheromone;GO:0000321 re-entry into mitotic cell cycle after pheromone arrest;GO:1903939 regulation of TORC2 signaling", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q06001-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06005-1", "uniprot_id": "LIPB_YEAST", "mass": 37237.0, "length": 328, "protein_name": "Octanoyltransferase, mitochondrial", "gene_name": "LIP2", "organism": "Yeast", "refseq_name": "lipoyl(octanoyl) transferase LIP2", "refseq_ac": "NP_013340", "gene_names_uniprotkb": "LIP2; L8083.16", "gene_names_refseq": "LIP2", "protein_names_uniprotkb": "Octanoyltransferase, mitochondrial; 2.3.1.181; Lipoate biosynthesis protein; Lipoate-protein ligase; Lipoyl ligase; Lipoyl/octanoyl transferase; Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase", "protein_names_refseq": "lipoyl(octanoyl) transferase LIP2", "tax_id": 559292, "disease": "dystonia (Disease Ontology:DOID:543); glycine encephalopathy (Disease Ontology:DOID:9268)", "pathway": " (sce:YLR239C); (R-SCE-9857492)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "14562106;24374639;9169871", "class_list": "", "function": "Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYN7", "ec_number_list": "2.3.1.181", "go_molecular_function": "GO:0016874 ligase activity;GO:0033819 lipoyl(octanoyl) transferase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0009249 protein lipoylation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q06005-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06011-1", "uniprot_id": "ECM19_YEAST", "mass": 12515.0, "length": 112, "protein_name": "Protein ECM19", "gene_name": "ECM19", "organism": "Yeast", "refseq_name": "Ecm19p", "refseq_ac": "NP_013494", "gene_names_uniprotkb": "ECM19", "gene_names_refseq": "ECM19", "protein_names_uniprotkb": "Protein ECM19; Extracellular mutant protein 19", "protein_names_refseq": "Ecm19p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR390W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562095;14562106;16823961;17322287;24374639;9169871;9335584", "class_list": "", "function": "May be involved in cell wall organization and biogenesis., [UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ25", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0071555 cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q06011-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06071-1", "uniprot_id": "BL1S1_YEAST", "mass": 14549.0, "length": 122, "protein_name": "Biogenesis of lysosome-related organelles complex 1 subunit BLS1", "gene_name": "BLS1", "organism": "Yeast", "refseq_name": "Bls1p", "refseq_ac": "NP_013512", "gene_names_uniprotkb": "BLS1", "gene_names_refseq": "BLS1", "protein_names_uniprotkb": "Biogenesis of lysosome-related organelles complex 1 subunit BLS1; BLOC-1 subunit BLS1; BLOS1-homolog", "protein_names_refseq": "Bls1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR408C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562095;14562106;17322287;18407956;21159114;23749301;24374639;33481703;33491328;9169871", "class_list": "", "function": "Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex involved in endosomal cargo sorting., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ42", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005768 endosome;GO:0031083 BLOC-1 complex", "go_biological_process": "GO:0032880 regulation of protein localization;GO:0007032 endosome organization", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q06071-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06090-1", "uniprot_id": "RM51_YEAST", "mass": 16124.0, "length": 140, "protein_name": "Large ribosomal subunit protein mL43", "gene_name": "MRPL51", "organism": "Yeast", "refseq_name": "mitochondrial 54S ribosomal protein mL43 MRPL51", "refseq_ac": "NP_015425", "gene_names_uniprotkb": "MRPL51; P8283.12", "gene_names_refseq": "MRPL51; mL43", "protein_names_uniprotkb": "Large ribosomal subunit protein mL43; 54S ribosomal protein L51, mitochondrial", "protein_names_refseq": "mitochondrial 54S ribosomal protein mL43 MRPL51", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR100W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "12392552;14562095;14562106;14576278;24374639;24675956;25609543;9169875", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane (Probable). Also has an extraribosomal function, being essential for mitochondrial genome integrity. May interact with MHR1 to take part in the mtDNA repair mechanism (PubMed:25609543)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W498", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0045454 cell redox homeostasis;GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q06090-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06098-1", "uniprot_id": "ISR1_YEAST", "mass": 49736.0, "length": 443, "protein_name": "Serine/threonine-protein kinase ISR1", "gene_name": "ISR1", "organism": "Yeast", "refseq_name": "putative protein kinase ISR1", "refseq_ac": "NP_015431", "gene_names_uniprotkb": "ISR1", "gene_names_refseq": "ISR1", "protein_names_uniprotkb": "Serine/threonine-protein kinase ISR1; 2.7.11.1; Inhibition of staurosporine resistance protein 1", "protein_names_refseq": "putative protein kinase ISR1", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR106W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562106;20489023;24374639;33481703;33491328;9169875;9720220", "class_list": "", "function": "Probable serine/threonine protein kinase which may function redundantly with MPK1-independent branch of the PCK1 pathway that is presumed to be required for the tolerance to high temperatures and staurosporine., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W4A4", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "", "go_biological_process": "GO:0018107 peptidyl-threonine phosphorylation;GO:0018105 peptidyl-serine phosphorylation;GO:0106279 negative regulation of UDP-N-acetylglucosamine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q06098-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06104-1", "uniprot_id": "GLD1_YEAST", "mass": 32710.0, "length": 294, "protein_name": "Golgi/endosome-localized DSC protein 1", "gene_name": "GLD1", "organism": "Yeast", "refseq_name": "Gld1p", "refseq_ac": "NP_015434", "gene_names_uniprotkb": "GLD1", "gene_names_refseq": "GLD1", "protein_names_uniprotkb": "Golgi/endosome-localized DSC protein 1", "protein_names_refseq": "Gld1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR109W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "12370439;12829295;16847258;17322287;24374639;29355480;9169875", "class_list": "", "function": "Component of the Golgi/endosome-localized DSC E3 ubiquitin ligase complex involved in the targeting of the DSC complex to the Golgi apparatus and endosome membranes via the AP3 pathway to ubiquitinate Golgi/endosome membrane proteins (PubMed:29355480). Competes with VLD1 to determine the subcellular localizations of the DSC complex (PubMed:29355480). May be required for cell cycle progression (PubMed:12829295)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W4A8;Q6B2S3", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005768 endosome;GO:0005783 endoplasmic reticulum;GO:0010008 endosome membrane;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0031503 protein-containing complex localization;GO:0140624 EGAD pathway", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q06104-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06108-1", "uniprot_id": "RGC1_YEAST", "mass": 120395.0, "length": 1083, "protein_name": "Regulator of the glycerol channel 1", "gene_name": "RGC1", "organism": "Yeast", "refseq_name": "Rgc1p", "refseq_ac": "NP_015440", "gene_names_uniprotkb": "RGC1", "gene_names_refseq": "RGC1", "protein_names_uniprotkb": "Regulator of the glycerol channel 1", "protein_names_refseq": "Rgc1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR115W)", "pathway_count": 1, "publication_count": 30, "publication_id_list": "12829295;14562095;14562106;15023338;15665377;17330950;17563356;18407956;19684113;19779198;19795423;19823750;19956799;20489023;20702584;21126336;21177495;22218487;23749301;24298058;24374639;28270554;30516470;31208443;32597660;33229814;33481703;33491328;34965436;9169875", "class_list": "", "function": "Positive regulator of FPS1 glycerol channel required for the glycerol efflux., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 8, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 8, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 8, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 64, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "D6W4B4", "ec_number_list": "", "go_molecular_function": "GO:0016247 channel regulator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0030036 actin cytoskeleton organization;GO:0090372 positive regulation of glycerol transport", "synthesized_glycan_count": 0, "hit_score": 4.0, "record_id": "Q06108-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06109-1", "uniprot_id": "RRG8_YEAST", "mass": 31133.0, "length": 277, "protein_name": "Required for respiratory growth protein 8, mitochondrial", "gene_name": "RRG8", "organism": "Yeast", "refseq_name": "Rrg8p", "refseq_ac": "NP_015441", "gene_names_uniprotkb": "RRG8", "gene_names_refseq": "MTA1; RRG8", "protein_names_uniprotkb": "Required for respiratory growth protein 8, mitochondrial", "protein_names_refseq": "Rrg8p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR116W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562095;14562106;18657191;19751518;24374639;9169875", "class_list": "", "function": "Required for respiratory activity and maintenance and expression of the mitochondrial genome., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W4B5", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0099617 matrix side of mitochondrial inner membrane", "go_biological_process": "GO:0097745 mitochondrial tRNA 5'-end processing", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q06109-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06116-1", "uniprot_id": "HOB2_YEAST", "mass": 285904.0, "length": 2489, "protein_name": "Protein YPR117W", "gene_name": "HOB2", "organism": "Yeast", "refseq_name": "Hob2p", "refseq_ac": "NP_015442", "gene_names_uniprotkb": "HOB2", "gene_names_refseq": "HOB2", "protein_names_uniprotkb": "Protein YPR117W; BLTP2B; Bridge-like lipid transfer protein family member 2B; HOB2; Protein hobbit 2", "protein_names_refseq": "Hob2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR117W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "18407956;19779198;23749301;24374639;33481703;33491328;35015055;35491307;9169875", "class_list": "", "function": "Tube-forming lipid transport protein which may bind to phosphatidylinositols and may affect phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) distribution., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 18, "predicted_n_glycosites": 18, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 20, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 18, "binding_glycan_count": 0, "secondary_ac_list": "D6W4B6", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0031966 mitochondrial membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q06116-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06134-1", "uniprot_id": "SPO77_YEAST", "mass": 55138.0, "length": 477, "protein_name": "Sporulation-specific protein 77", "gene_name": "SPO77", "organism": "Yeast", "refseq_name": "Spo77p", "refseq_ac": "NP_013445", "gene_names_uniprotkb": "SPO77", "gene_names_refseq": "SPO77", "protein_names_uniprotkb": "Sporulation-specific protein 77", "protein_names_refseq": "Spo77p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR341W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "11470404;15590821;24374639;9169871", "class_list": "", "function": "Required for spore wall assembly and ascus formation., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYX9", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:1903024 positive regulation of ascospore-type prospore membrane formation;GO:0030437 ascospore formation;GO:0030476 ascospore wall assembly", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q06134-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06149-1", "uniprot_id": "PDR8_YEAST", "mass": 81274.0, "length": 701, "protein_name": "Transcription factor PDR8", "gene_name": "PDR8", "organism": "Yeast", "refseq_name": "Pdr8p", "refseq_ac": "NP_013368", "gene_names_uniprotkb": "PDR8; L8479.13", "gene_names_refseq": "PDR8", "protein_names_uniprotkb": "Transcription factor PDR8; Pleiotropic drug resistance protein 8", "protein_names_refseq": "Pdr8p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR266C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "12529331;14562095;24374639;33491328;9169871", "class_list": "", "function": "Up-regulates the transcription of the genes for ATP-binding cassette (ABC) transporters YOR1 and PDR15, for major facilitator superfamily transporter AZR1, for pleiotropic drug resistance SNG1, for alpha-glucosidase YJL216C and for YLL056C., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYR4", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0033554 cellular response to stress", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q06149-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06162-1", "uniprot_id": "NKP2_YEAST", "mass": 17862.0, "length": 153, "protein_name": "Inner kinetochore subunit NKP2", "gene_name": "NKP2", "organism": "Yeast", "refseq_name": "Nkp2p", "refseq_ac": "NP_013419", "gene_names_uniprotkb": "NKP2", "gene_names_refseq": "NKP2", "protein_names_uniprotkb": "Inner kinetochore subunit NKP2; Constitutive centromere-associated network protein NKP2; Non-essential kinetochore protein 2", "protein_names_refseq": "Nkp2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR315W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "12408861;14562095;14562106;17322287;22561346;24374639;29046335;33491328;9169871", "class_list": "", "function": "Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYV9", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0000776 kinetochore;GO:0031511 Mis6-Sim4 complex", "go_biological_process": "GO:0007059 chromosome segregation;GO:0008608 attachment of spindle microtubules to kinetochore;GO:0051301 cell division;GO:0051321 meiotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q06162-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06169-1", "uniprot_id": "PEX30_YEAST", "mass": 59462.0, "length": 523, "protein_name": "Peroxisomal membrane protein PEX30", "gene_name": "PEX30", "organism": "Yeast", "refseq_name": "peroxisome biogenesis protein", "refseq_ac": "NP_013428", "gene_names_uniprotkb": "PEX30", "gene_names_refseq": "PEX30", "protein_names_uniprotkb": "Peroxisomal membrane protein PEX30; Peroxin-30", "protein_names_refseq": "peroxisome biogenesis protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR324W)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "17322287;18407956;19779198;19795423;19823750;20702584;21126336;22218487;22814378;23749301;24374639;32597660;33481703;33491328;35218395;9169871", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 21, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYW6;Q66R43", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding", "go_cellular_component": "GO:0005777 peroxisome;GO:0005778 peroxisomal membrane;GO:0005783 endoplasmic reticulum;GO:0071944 cell periphery;GO:0071782 endoplasmic reticulum tubular network", "go_biological_process": "GO:1900063 regulation of peroxisome organization;GO:0007031 peroxisome organization;GO:0032581 ER-dependent peroxisome organization", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q06169-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06179-1", "uniprot_id": "FMP27_YEAST", "mass": 303479.0, "length": 2628, "protein_name": "Protein FMP27, mitochondrial", "gene_name": "FMP27", "organism": "Yeast", "refseq_name": "Fmp27p", "refseq_ac": "NP_013559", "gene_names_uniprotkb": "FMP27; HOB1", "gene_names_refseq": "FMP27; HOB1", "protein_names_uniprotkb": "Protein FMP27, mitochondrial; BLTP2A; Bridge-like lipid transfer protein family member 2A; Found in mitochondrial proteome protein 27; HOB1; Protein hobbit 1", "protein_names_refseq": "Fmp27p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR454W)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "14562106;14576278;17330950;18407956;19779198;19795423;19823750;21126336;23749301;24374639;32597660;33481703;33491328;34415038;34965436;35015055;35491307;9169871", "class_list": "", "function": "Tube-forming lipid transport protein which binds to phosphatidylinositols and affects phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) distribution., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 16, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ88", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005886 plasma membrane;GO:0031966 mitochondrial membrane;GO:0005789 endoplasmic reticulum membrane;GO:0044233 mitochondria-associated endoplasmic reticulum membrane contact site", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "Q06179-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06188-1", "uniprot_id": "PDP3_YEAST", "mass": 35508.0, "length": 304, "protein_name": "NuA3 HAT complex component PDP3", "gene_name": "PDP3", "organism": "Yeast", "refseq_name": "Pdp3p", "refseq_ac": "NP_013560", "gene_names_uniprotkb": "PDP3", "gene_names_refseq": "PDP3", "protein_names_uniprotkb": "NuA3 HAT complex component PDP3; PWWP domain-containing protein YLR455W", "protein_names_refseq": "Pdp3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR455W)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "14562095;14562106;16278933;19795423;19823750;21126336;22932476;24374639;25104842;25473596;28108585;32597660;33481703;33491328;33502312;35273076;9169871", "class_list": "", "function": "Histone-binding component of the NuA3b histone acetyltransferase complex. Targets the NuA3b HAT complex via histone H3K36me3 to the coding regions of actively transcribed genes to coordinate transcription elongation (PubMed:25104842, PubMed:28108585). Stimulates elongation by RNA polymerase II in vitro (PubMed:35273076)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ89", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0000993 RNA polymerase II complex binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:1990468 NuA3b histone acetyltransferase complex;GO:0033100 NuA3 histone acetyltransferase complex", "go_biological_process": "GO:0032968 positive regulation of transcription elongation by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q06188-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06200-1", "uniprot_id": "ECM7_YEAST", "mass": 50328.0, "length": 448, "protein_name": "Protein ECM7", "gene_name": "ECM7", "organism": "Yeast", "refseq_name": "Ecm7p", "refseq_ac": "NP_013548", "gene_names_uniprotkb": "ECM7; ZRG15", "gene_names_refseq": "ECM7; ZRG15", "protein_names_uniprotkb": "Protein ECM7; Extracellular mutant protein 7; Zinc-regulated gene 15 protein", "protein_names_refseq": "Ecm7p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR443W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10978274;12524434;15905473;16847258;19779198;23749301;24374639;33481703;33491328;9169871;9335584", "class_list": "", "function": "May be involved in cell wall organization and biogenesis., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ78;Q2VQX1", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0000324 fungal-type vacuole;GO:0051285 cell cortex of cell tip", "go_biological_process": "GO:0006816 calcium ion transport;GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q06200-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06214-1", "uniprot_id": "JIP5_YEAST", "mass": 55264.0, "length": 492, "protein_name": "WD repeat-containing protein JIP5", "gene_name": "JIP5", "organism": "Yeast", "refseq_name": "Jip5p", "refseq_ac": "NP_015495", "gene_names_uniprotkb": "JIP5", "gene_names_refseq": "JIP5", "protein_names_uniprotkb": "WD repeat-containing protein JIP5; Jumonji domain-interacting protein 5", "protein_names_refseq": "Jip5p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR169W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "12748633;14562095;14562106;14690591;15905473;17043893;24374639;33481703;9169875", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W4H0", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus", "go_biological_process": "GO:0042273 ribosomal large subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q06214-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06216-1", "uniprot_id": "PIG1_YEAST", "mass": 74146.0, "length": 648, "protein_name": "Serine/threonine-protein phosphatase 1 regulatory subunit PIG1", "gene_name": "PIG1", "organism": "Yeast", "refseq_name": "protein phosphatase regulator PIG1", "refseq_ac": "NP_013375", "gene_names_uniprotkb": "PIG1; L9328.2", "gene_names_refseq": "PIG1", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase 1 regulatory subunit PIG1", "protein_names_refseq": "protein phosphatase regulator PIG1", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR273C); (R-SCE-3322077)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "17322287;19684113;19779198;24374639;24440502;33481703;33491328;9046081;9169871", "class_list": "", "function": "Regulates the activity of glycogen synthase. It is most probably a regulatory subunit for protein phosphatase type 1., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYS0;E9P964", "ec_number_list": "", "go_molecular_function": "GO:0019888 protein phosphatase regulator activity;GO:0008157 protein phosphatase 1 binding;GO:2001069 glycogen binding", "go_cellular_component": "GO:0000164 protein phosphatase type 1 complex", "go_biological_process": "GO:0005978 glycogen biosynthetic process;GO:0005979 regulation of glycogen biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q06216-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06236-1", "uniprot_id": "SHH4_YEAST", "mass": 18632.0, "length": 168, "protein_name": "Mitochondrial inner membrane protein SHH4", "gene_name": "SHH4", "organism": "Yeast", "refseq_name": "protein SHH4", "refseq_ac": "NP_013265", "gene_names_uniprotkb": "SHH4", "gene_names_refseq": "SHH4", "protein_names_uniprotkb": "Mitochondrial inner membrane protein SHH4; SDH4 homolog", "protein_names_refseq": "protein SHH4", "tax_id": 559292, "disease": "paraganglioma (Disease Ontology:DOID:0050773); mitochondrial complex II deficiency (Disease Ontology:DOID:0060537); pheochromocytoma/paraganglioma syndrome 1 (Disease Ontology:DOID:0061216); Carney-Stratakis syndrome (Disease Ontology:DOID:0080533)", "pathway": " (sce:YLR164W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10637294;14576278;22152483;24374639;9169871", "class_list": "", "function": "Homolog of SDH4, but does not seem to be a stoichiometric subunit of either the succinate dehydrogenase (SDH) complex or the mitochondrial inner membrane translocase TIM22 complex., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYH0", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0048039 ubiquinone binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0045273 respiratory chain complex II (succinate dehydrogenase)", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0006121 mitochondrial electron transport, succinate to ubiquinone", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q06236-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06244-1", "uniprot_id": "PUS5_YEAST", "mass": 29359.0, "length": 254, "protein_name": "21S rRNA pseudouridine(2819) synthase", "gene_name": "PUS5", "organism": "Yeast", "refseq_name": "pseudouridine synthase PUS5", "refseq_ac": "NP_013266", "gene_names_uniprotkb": "PUS5", "gene_names_refseq": "PUS5", "protein_names_uniprotkb": "21S rRNA pseudouridine(2819) synthase; 5.4.99.43; Pseudouridine synthase 5; Pseudouridylate synthase PUS5; Uracil hydrolyase PUS5", "protein_names_refseq": "pseudouridine synthase PUS5", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR165C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10756195;17322287;24374639;25219674;9169871", "class_list": "", "function": "Pseudouridylate synthase responsible for the pseudouridine-2819 formation in mitochondrial 21S rRNA. May modulate the efficiency or the fidelity of the mitochondrial translation machinery., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYH1", "ec_number_list": "5.4.99.43", "go_molecular_function": "GO:0003723 RNA binding;GO:0009982 pseudouridine synthase activity;GO:0004730 pseudouridylate synthase activity;GO:0160143 21S rRNA pseudouridine(2819) synthase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0000455 enzyme-directed rRNA pseudouridine synthesis;GO:0000154 rRNA modification;GO:0001522 pseudouridine synthesis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q06244-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06315-1", "uniprot_id": "SKG3_YEAST", "mass": 114111.0, "length": 1026, "protein_name": "Protein SKG3", "gene_name": "SKG3", "organism": "Yeast", "refseq_name": "Skg3p", "refseq_ac": "NP_013288", "gene_names_uniprotkb": "SKG3", "gene_names_refseq": "SKG3", "protein_names_uniprotkb": "Protein SKG3; Suppressor of lethality of KEX2-GAS1 double null mutant protein 3", "protein_names_refseq": "Skg3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR187W)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "14562095;15023338;15645486;17287358;17330950;17563356;18407956;19779198;19795423;19823750;20489023;20702584;21126336;21177495;22218487;23749301;24374639;32597660;33229814;33481703;33491328;9169871", "class_list": "", "function": "May play a role in cell wall integrity., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 10, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 10, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 10, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 92, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 10, "binding_glycan_count": 0, "secondary_ac_list": "D6VYJ0", "ec_number_list": "", "go_molecular_function": "GO:0004672 protein kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005933 cellular bud;GO:0005934 cellular bud tip;GO:0005935 cellular bud neck", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 3.4, "record_id": "Q06315-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06325-1", "uniprot_id": "YPS7_YEAST", "mass": 64498.0, "length": 596, "protein_name": "Aspartic proteinase yapsin-7", "gene_name": "YPS7", "organism": "Yeast", "refseq_name": "putative aspartic endopeptidase", "refseq_ac": "NP_010636", "gene_names_uniprotkb": "YPS7", "gene_names_refseq": "YPS7", "protein_names_uniprotkb": "Aspartic proteinase yapsin-7; 3.4.23.-", "protein_names_refseq": "putative aspartic endopeptidase", "tax_id": 559292, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); frontotemporal dementia (Disease Ontology:DOID:9255)", "pathway": " (sce:YDR349C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562095;14562106;16087741;17322287;24374639;9169867", "class_list": "", "function": "", "predicted_glycosites": 15, "predicted_n_glycosites": 15, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 15, "binding_glycan_count": 0, "secondary_ac_list": "D6VSX9;Q66RD4", "ec_number_list": "", "go_molecular_function": "GO:0004190 aspartic-type endopeptidase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0009277 fungal-type cell wall", "go_biological_process": "GO:0016485 protein processing;GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q06325-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06328-1", "uniprot_id": "YPQ2_YEAST", "mass": 35179.0, "length": 317, "protein_name": "Vacuolar arginine/histidine antiporter YPQ2", "gene_name": "YPQ2", "organism": "Yeast", "refseq_name": "Ypq2p", "refseq_ac": "NP_010639", "gene_names_uniprotkb": "YPQ2", "gene_names_refseq": "YPQ2", "protein_names_uniprotkb": "Vacuolar arginine/histidine antiporter YPQ2; PQ-loop repeat-containing protein 2", "protein_names_refseq": "Ypq2p", "tax_id": 559292, "disease": "lysosomal storage disease (Disease Ontology:DOID:3211)", "pathway": " (sce:YDR352W); (R-SCE-5223345)", "pathway_count": 2, "publication_count": 16, "publication_id_list": "14562095;14562106;17330950;18407956;19684113;19779198;23169667;23749301;24374639;26928127;31636363;32597660;32776922;33481703;33491328;9169867", "class_list": "", "function": "Amino acid transporter that moves arginine across the vacuolar membrane (PubMed:23169667, PubMed:26928127, PubMed:31636363, PubMed:32776922). Active during nitrogen starvation when it exports stored vacuolar arginine to the cytosol, for use as a nitrogen source (PubMed:32776922). Has been shown to function as an arginine/histidine antiporter when substrate is present on both sides of the membrane, but may also function as a uniporter (PubMed:23169667, PubMed:32776922)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VSY2", "ec_number_list": "", "go_molecular_function": "GO:0015174 basic amino acid transmembrane transporter activity;GO:0061459 L-arginine transmembrane transporter activity", "go_cellular_component": "GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:1903826 L-arginine transmembrane transport;GO:0034488 basic amino acid transmembrane export from vacuole;GO:0034490 basic amino acid transmembrane import into vacuole", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q06328-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06333-1", "uniprot_id": "BL1S4_YEAST", "mass": 13957.0, "length": 122, "protein_name": "Biogenesis of lysosome-related organelles complex 1 subunit CNL1", "gene_name": "CNL1", "organism": "Yeast", "refseq_name": "Cnl1p", "refseq_ac": "NP_010644", "gene_names_uniprotkb": "CNL1", "gene_names_refseq": "CNL1", "protein_names_uniprotkb": "Biogenesis of lysosome-related organelles complex 1 subunit CNL1; BLOC-1 subunit CNL1; CNO-like protein 1", "protein_names_refseq": "Cnl1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR357C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562095;14562106;17322287;19779198;21159114;24374639;33481703;33491328;9169867", "class_list": "", "function": "Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex that is involved in endosomal cargo sorting., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSY6", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005768 endosome;GO:0031083 BLOC-1 complex", "go_biological_process": "GO:0032880 regulation of protein localization;GO:0007032 endosome organization", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q06333-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06336-1", "uniprot_id": "GGA1_YEAST", "mass": 62320.0, "length": 557, "protein_name": "ADP-ribosylation factor-binding protein GGA1", "gene_name": "GGA1", "organism": "Yeast", "refseq_name": "ubiquitin-binding protein", "refseq_ac": "NP_010645", "gene_names_uniprotkb": "GGA1; D9476.2", "gene_names_refseq": "GGA1", "protein_names_uniprotkb": "ADP-ribosylation factor-binding protein GGA1; Golgi-localized, gamma ear-containing, ARF-binding protein 1", "protein_names_refseq": "ubiquitin-binding protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR358W)", "pathway_count": 1, "publication_count": 21, "publication_id_list": "10747088;11124697;14562106;15665377;17330950;17563356;18407956;19779198;19795423;19823750;20702584;21126336;21177495;22218487;23749301;24374639;30516470;32597660;33481703;33491328;9169867", "class_list": "", "function": "May play a role in the regulation of membrane traffic through the trans-Golgi network., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 25, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSY7", "ec_number_list": "", "go_molecular_function": "GO:0035091 phosphatidylinositol binding;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0006895 Golgi to endosome transport;GO:0006896 Golgi to vacuole transport", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "Q06336-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06338-1", "uniprot_id": "BCP1_YEAST", "mass": 32661.0, "length": 283, "protein_name": "Protein BCP1", "gene_name": "BCP1", "organism": "Yeast", "refseq_name": "protein-transporting protein BCP1", "refseq_ac": "NP_010648", "gene_names_uniprotkb": "BCP1", "gene_names_refseq": "BCP1", "protein_names_uniprotkb": "Protein BCP1", "protein_names_refseq": "protein-transporting protein BCP1", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR361C)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "12912920;14562095;14562106;16330754;17322287;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22814378;23749301;24374639;32597660;33481703;33491328;9169867", "class_list": "", "function": "Involved in nuclear export of the lipid kinase MSS4 and of the 60S ribosomal subunit. May also play a role in directing MSS4 to the plasma membrane. Plays a role in actin cytoskeleton organization and vesicular transport., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSY9", "ec_number_list": "", "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0044183 protein folding chaperone", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0000055 ribosomal large subunit export from nucleus;GO:0006611 protein export from nucleus", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "Q06338-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06349-1", "uniprot_id": "DXO1_YEAST", "mass": 50492.0, "length": 442, "protein_name": "Decapping and exoribonuclease protein 1", "gene_name": "DXO1", "organism": "Yeast", "refseq_name": "Dxo1p", "refseq_ac": "NP_010658", "gene_names_uniprotkb": "DXO1", "gene_names_refseq": "DXO1", "protein_names_uniprotkb": "Decapping and exoribonuclease protein 1; 3.1.13.-; 3.6.1.-; 5'-3' exoribonuclease DXO1; DeNADding enzyme DXO1; NAD-capped RNA hydrolase DXO1", "protein_names_refseq": "Dxo1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR370C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562095;14562106;22961381;24374639;33491328;9169867", "class_list": "", "function": "Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA (By similarity). The NAD-cap is present at the 5'-end of some RNAs and snoRNAs. In contrast to the canonical 5'-end N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay (By similarity). Also acts as a non-canonical decapping enzyme that removes the entire cap structure of m7G capped or incompletely capped RNAs (PubMed:22961381). Has decapping activity toward incomplete 5'-end m7G cap mRNAs such as unmethylated 5'-end-capped RNA (cap0), while it has no activity toward 2'-O-ribose methylated m7G cap (cap1) (PubMed:22961381). Also has 5'-3' exonuclease activity (PubMed:22961381)., [UniProtKB, UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VT01", "ec_number_list": "3.6.1.-;3.1.13.-", "go_molecular_function": "GO:0034353 mRNA 5'-diphosphatase activity;GO:0003723 RNA binding;GO:0046872 metal ion binding;GO:0000166 nucleotide binding;GO:0004534 5'-3' RNA exonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0000956 nuclear-transcribed mRNA catabolic process;GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay;GO:0000470 maturation of LSU-rRNA;GO:0110155 NAD-cap decapping", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q06349-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06350-1", "uniprot_id": "CHI2_YEAST", "mass": 59118.0, "length": 511, "protein_name": "Sporulation-specific chitinase 2", "gene_name": "CTS2", "organism": "Yeast", "refseq_name": "putative chitinase", "refseq_ac": "NP_010659", "gene_names_uniprotkb": "CTS2; D9481.7", "gene_names_refseq": "CTS2", "protein_names_uniprotkb": "Sporulation-specific chitinase 2; 3.2.1.14", "protein_names_refseq": "putative chitinase", "tax_id": 559292, "disease": "invasive aspergillosis (Disease Ontology:DOID:0050073); sinusitis (Disease Ontology:DOID:0050127); idiopathic pulmonary fibrosis (Disease Ontology:DOID:0050156); small cell carcinoma (Disease Ontology:DOID:0050685); colorectal carcinoma (Disease Ontology:DOID:0080199); leprosy (Disease Ontology:DOID:1024); prostate carcinoma (Disease Ontology:DOID:10286); asbestosis (Disease Ontology:DOID:10320); silicosis (Disease Ontology:DOID:10325); pre-eclampsia (Disease Ontology:DOID:10591); hypertension (Disease Ontology:DOID:10763); sarcoidosis (Disease Ontology:DOID:11335); bronchopulmonary dysplasia (Disease Ontology:DOID:11650); allergic disease (Disease Ontology:DOID:1205); cryptococcosis (Disease Ontology:DOID:12053); temporal arteritis (Disease Ontology:DOID:13375); pulmonary sarcoidosis (Disease Ontology:DOID:13406); aspergillosis (Disease Ontology:DOID:13564); endometrial cancer (Disease Ontology:DOID:1380); cystic fibrosis (Disease Ontology:DOID:1485); candidiasis (Disease Ontology:DOID:1508); breast cancer (Disease Ontology:DOID:1612); melanoma (Disease Ontology:DOID:1909); Gaucher's disease (Disease Ontology:DOID:1926); arteriosclerosis (Disease Ontology:DOID:2349); relapsing-remitting multiple sclerosis (Disease Ontology:DOID:2378); ovarian cancer (Disease Ontology:DOID:2394); asthma (Disease Ontology:DOID:2841); pulmonary tuberculosis (Disease Ontology:DOID:2957); glioblastoma (Disease Ontology:DOID:3068); interstitial lung disease (Disease Ontology:DOID:3082); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); chondrosarcoma (Disease Ontology:DOID:3371); coronary artery disease (Disease Ontology:DOID:3393); pulmonary fibrosis (Disease Ontology:DOID:3770); lung non-small cell carcinoma (Disease Ontology:DOID:3908); tuberculosis (Disease Ontology:DOID:399); systemic scleroderma (Disease Ontology:DOID:418); allergic rhinitis (Disease Ontology:DOID:4481); schizophrenia (Disease Ontology:DOID:5419); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); rheumatoid arthritis (Disease Ontology:DOID:7148); neuromyelitis optica (Disease Ontology:DOID:8869); acute myeloid leukemia (Disease Ontology:DOID:9119); type 2 diabetes mellitus (Disease Ontology:DOID:9352); intrinsic asthma (Disease Ontology:DOID:9360); allergic asthma (Disease Ontology:DOID:9415); bacterial meningitis (Disease Ontology:DOID:9470); multiple myeloma (Disease Ontology:DOID:9538); bronchiectasis (Disease Ontology:DOID:9563); type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": " (sce:YDR371W); (R-SCE-189085); (R-SCE-6798695)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "14562106;24374639;9169867", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 52, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "D6VT02", "ec_number_list": "3.5.3.1;3.4.23.25;1.1.1.42;2.3.1.16;5.4.2.2;2.7.1.35;3.5.1.3;3.2.1.14;3.5.4.5;3.4.11.-;3.3.2.10", "go_molecular_function": "GO:0004568 chitinase activity;GO:0008843 endochitinase activity;GO:0008061 chitin binding;GO:0035885 exochitinase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005737 cytoplasm", "go_biological_process": "GO:0000272 polysaccharide catabolic process;GO:0006032 chitin catabolic process;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q06350-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06405-1", "uniprot_id": "ATPK_YEAST", "mass": 11312.0, "length": 101, "protein_name": "ATP synthase subunit f, mitochondrial", "gene_name": "ATP17", "organism": "Yeast", "refseq_name": "F1F0 ATP synthase subunit f", "refseq_ac": "NP_010665", "gene_names_uniprotkb": "ATP17; D9481.21", "gene_names_refseq": "ATP17", "protein_names_uniprotkb": "ATP synthase subunit f, mitochondrial", "protein_names_refseq": "F1F0 ATP synthase subunit f", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR377W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562106;24374639;33481703;9169867;9288937", "class_list": "", "function": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VT09", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0045259 proton-transporting ATP synthase complex", "go_biological_process": "GO:0015986 proton motive force-driven ATP synthesis;GO:1902600 proton transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q06405-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06417-1", "uniprot_id": "TDA5_YEAST", "mass": 36677.0, "length": 326, "protein_name": "Uncharacterized oxidoreductase TDA5", "gene_name": "TDA5", "organism": "Yeast", "refseq_name": "Tda5p", "refseq_ac": "NP_013530", "gene_names_uniprotkb": "TDA5", "gene_names_refseq": "TDA5", "protein_names_uniprotkb": "Uncharacterized oxidoreductase TDA5; 1.-.-.-; Topoisomerase I damage affected protein 5", "protein_names_refseq": "Tda5p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR426W); (R-SCE-193144); (R-SCE-2187335); (R-SCE-5365859); (R-SCE-8964572)", "pathway_count": 5, "publication_count": 8, "publication_id_list": "12077312;14562106;14576278;16121259;21173034;24374639;33491328;9169871", "class_list": "", "function": "Involved in the resistance to DNA-damaging agents., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ62", "ec_number_list": "1.-.-.-", "go_molecular_function": "GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0009410 response to xenobiotic stimulus", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q06417-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06436-1", "uniprot_id": "MAG2_YEAST", "mass": 76317.0, "length": 670, "protein_name": "E3 ubiquitin-protein ligase MAG2", "gene_name": "MAG2", "organism": "Yeast", "refseq_name": "RING-type E3 ubiquitin transferase MAG2", "refseq_ac": "NP_013531", "gene_names_uniprotkb": "MAG2", "gene_names_refseq": "MAG2", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase MAG2; 2.3.2.27", "protein_names_refseq": "RING-type E3 ubiquitin transferase MAG2", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR427W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562095;14562106;17322287;23749301;24374639;30893611;9169871", "class_list": "", "function": "E3 ubiquitin-protein ligase involved in the degradation of non-functional 18S rRNAs in response to stalled ribosomes (PubMed:30893611). Catalyzes monoubiquitination of RPS3/uS3 in response to stalled ribosomes, initiating a HEL2-dependent response that activates the degradation of non-functional 18S rRNAs (PubMed:30893611)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ63", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0022626 cytosolic ribosome", "go_biological_process": "GO:0070651 nonfunctional rRNA decay;GO:1990116 ribosome-associated ubiquitin-dependent protein catabolic process;GO:0006513 protein monoubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q06436-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06451-1", "uniprot_id": "TPO3_YEAST", "mass": 68066.0, "length": 622, "protein_name": "Polyamine transporter 3", "gene_name": "TPO3", "organism": "Yeast", "refseq_name": "spermine transporter", "refseq_ac": "NP_015482", "gene_names_uniprotkb": "TPO3; P9584.7", "gene_names_refseq": "TPO3", "protein_names_uniprotkb": "Polyamine transporter 3", "protein_names_refseq": "spermine transporter", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR156C)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "11171066;11875433;12562762;14562095;14562106;15066780;16847258;17322287;17330950;17563356;18407956;19684113;19779198;21177495;22218487;23749301;24374639;32597660;33481703;33491328;34965436;9169875", "class_list": "", "function": "Cell membrane polyamine/proton antiporter, involved in the detoxification of excess polyamines in the cytoplasm. Recognizes spermine, but not spermidine., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 25, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W4F2", "ec_number_list": "", "go_molecular_function": "GO:0015297 antiporter activity;GO:0000297 spermine transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0000296 spermine transport;GO:0055085 transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "Q06451-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06466-1", "uniprot_id": "TDA6_YEAST", "mass": 53809.0, "length": 467, "protein_name": "Putative vacuolar protein sorting-associated protein TDA6", "gene_name": "TDA6", "organism": "Yeast", "refseq_name": "Tda6p", "refseq_ac": "NP_015483", "gene_names_uniprotkb": "TDA6", "gene_names_refseq": "TDA6", "protein_names_uniprotkb": "Putative vacuolar protein sorting-associated protein TDA6; Topoisomerase I damage affected protein 6", "protein_names_refseq": "Tda6p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR157W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "17608707;21173034;24374639;9169875", "class_list": "", "function": "Involved in vacuolar protein sorting., [UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6W4F3", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane;GO:0071944 cell periphery;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0015031 protein transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q06466-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06469-1", "uniprot_id": "CUR1_YEAST", "mass": 29163.0, "length": 252, "protein_name": "Curing of [URE3] protein 1", "gene_name": "CUR1", "organism": "Yeast", "refseq_name": "Cur1p", "refseq_ac": "NP_015484", "gene_names_uniprotkb": "CUR1", "gene_names_refseq": "CUR1", "protein_names_uniprotkb": "Curing of [URE3] protein 1", "protein_names_refseq": "Cur1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR158W)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "18833194;24374639;9169875", "class_list": "", "function": "Involved in the curing of prion [URE3]. Nuclear localization of this protein may suggest a role in transcription regulation, so it might exert an effect on [URE3] through known prion-curing chaperones or BTN2., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W4F4", "ec_number_list": "", "go_molecular_function": "GO:0051087 protein-folding chaperone binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006886 intracellular protein transport;GO:0006457 protein folding;GO:0034504 protein localization to nucleus", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q06469-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06485-1", "uniprot_id": "ATG33_YEAST", "mass": 20400.0, "length": 197, "protein_name": "Autophagy-related protein 33", "gene_name": "ATG33", "organism": "Yeast", "refseq_name": "Atg33p", "refseq_ac": "NP_013460", "gene_names_uniprotkb": "ATG33", "gene_names_refseq": "ATG33", "protein_names_uniprotkb": "Autophagy-related protein 33", "protein_names_refseq": "Atg33p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR356W)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "14562095;17322287;17330950;17563356;18407956;19779198;19793921;20364111;23749301;24374639;24909858;33481703;33491328;34965436;9169871", "class_list": "", "function": "Involved in the selective degradation of mitochondria via autophagy during starvation and at post-log phase., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYZ4", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0016236 macroautophagy;GO:0000422 autophagy of mitochondrion", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q06485-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06490-1", "uniprot_id": "THI22_YEAST", "mass": 63298.0, "length": 572, "protein_name": "Thiamine biosynthesis protein THI22", "gene_name": "THI22", "organism": "Yeast", "refseq_name": "putative phosphomethylpyrimidine kinase", "refseq_ac": "NP_015446", "gene_names_uniprotkb": "THI22", "gene_names_refseq": "THI22", "protein_names_uniprotkb": "Thiamine biosynthesis protein THI22", "protein_names_refseq": "putative phosphomethylpyrimidine kinase", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR121W)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10383756;24374639;9169875", "class_list": "", "function": "Is not required for thiamine biosynthesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W4C0", "ec_number_list": "", "go_molecular_function": "GO:0008902 hydroxymethylpyrimidine kinase activity;GO:0008972 phosphomethylpyrimidine kinase activity;GO:0050334 thiaminase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005829 cytosol", "go_biological_process": "GO:0009228 thiamine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q06490-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06494-1", "uniprot_id": "PLR1_YEAST", "mass": 38601.0, "length": 345, "protein_name": "Putative pyridoxal reductase", "gene_name": "", "organism": "Yeast", "refseq_name": "pyridoxine 4-dehydrogenase", "refseq_ac": "NP_015452", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Putative pyridoxal reductase; 1.1.1.65; PL reductase; PL-red", "protein_names_refseq": "pyridoxine 4-dehydrogenase", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR127W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562095;14562106;18407956;21126336;24374639;33491328;9169875", "class_list": "", "function": "Catalyzes the reduction of pyridoxal (PL) with NADPH and oxidation of pyridoxine (PN) with NADP(+)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W4C4", "ec_number_list": "1.1.1.65", "go_molecular_function": "GO:0008106 alcohol dehydrogenase (NADP+) activity;GO:0050236 pyridoxine 4-dehydrogenase (NADP+) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0042820 vitamin B6 catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q06494-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06497-1", "uniprot_id": "ANT1_YEAST", "mass": 36367.0, "length": 328, "protein_name": "Peroxisomal adenine nucleotide transporter 1", "gene_name": "ANT1", "organism": "Yeast", "refseq_name": "Ant1p", "refseq_ac": "NP_015453", "gene_names_uniprotkb": "ANT1", "gene_names_refseq": "ANT1", "protein_names_uniprotkb": "Peroxisomal adenine nucleotide transporter 1", "protein_names_refseq": "Ant1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR128C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "11390660;11566870;12071844;14562095;14562106;15219179;15316083;23749301;24374639;33491328;35127709;9169875", "class_list": "", "function": "Major importer of ATP into the peroxisomal lumen that exchanges ATP for ADP or AMP (PubMed:11566870, PubMed:11390660, PubMed:15219179, PubMed:35127709). Can also transport other adenine nucleotides (PubMed:11566870). This transport is accompanied by a proton transport from the peroxisomal lumen to the cytosol (PubMed:15219179, PubMed:15316083)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W4C5", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0000295 adenine nucleotide transmembrane transporter activity;GO:0005347 ATP transmembrane transporter activity;GO:0015217 ADP transmembrane transporter activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005778 peroxisomal membrane", "go_biological_process": "GO:0006635 fatty acid beta-oxidation;GO:0007031 peroxisome organization;GO:0015866 ADP transport;GO:0015867 ATP transport;GO:1902600 proton transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q06497-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06538-1", "uniprot_id": "CSC1_YEAST", "mass": 89344.0, "length": 782, "protein_name": "Calcium permeable stress-gated cation channel 1", "gene_name": "CSC1", "organism": "Yeast", "refseq_name": "Csc1p", "refseq_ac": "NP_013342", "gene_names_uniprotkb": "CSC1", "gene_names_refseq": "CSC1", "protein_names_uniprotkb": "Calcium permeable stress-gated cation channel 1; ScCSC1", "protein_names_refseq": "Csc1p", "tax_id": 559292, "disease": "developmental and epileptic encephalopathy 118 (Disease Ontology:DOID:0061176); hypomyelinating leukodystrophy 19 (Disease Ontology:DOID:0070400); hereditary spastic paraplegia 87 (Disease Ontology:DOID:0070456); focal segmental glomerulosclerosis (Disease Ontology:DOID:1312); central nervous system disease (Disease Ontology:DOID:331)", "pathway": " (sce:YLR241W); (R-SCE-6798695)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "16847258;18407956;24374639;24503647;32597660;33491328;9169871", "class_list": "", "function": "Acts as an osmosensitive calcium-permeable cation channel., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VYN9", "ec_number_list": "", "go_molecular_function": "GO:0005227 calcium-activated cation channel activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0006812 monoatomic cation transport", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q06538-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06543-1", "uniprot_id": "GPN3_YEAST", "mass": 30653.0, "length": 272, "protein_name": "GPN-loop GTPase 3", "gene_name": "GPN3", "organism": "Yeast", "refseq_name": "putative signal sequence-binding GTPase GPN3", "refseq_ac": "NP_013344", "gene_names_uniprotkb": "GPN3", "gene_names_refseq": "GPN3", "protein_names_uniprotkb": "GPN-loop GTPase 3; 3.6.5.-", "protein_names_refseq": "putative signal sequence-binding GTPase GPN3", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR243W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "21532343;23267056;23324351;24374639;9169871", "class_list": "", "function": "Small GTPase involved in the correct assembly of RNA polymerase II and III (RNAPII and RNAPIII) complexes, ensuring their proper nuclear import of RNAPII (PubMed:23267056). Promotes sister chromatid separation during anaphase (PubMed:23324351)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYP1", "ec_number_list": "3.6.5.2;3.6.5.3;3.6.5.-;3.6.5.4;3.6.5.5", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding", "go_cellular_component": "", "go_biological_process": "GO:0007064 mitotic sister chromatid cohesion;GO:0006606 protein import into nucleus", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q06543-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06563-1", "uniprot_id": "SYM1_YEAST", "mass": 22915.0, "length": 197, "protein_name": "Protein SYM1", "gene_name": "SYM1", "organism": "Yeast", "refseq_name": "ethanol metabolism protein", "refseq_ac": "NP_013352", "gene_names_uniprotkb": "SYM1", "gene_names_refseq": "SYM1", "protein_names_uniprotkb": "Protein SYM1; Stress-inducible yeast MPV17 protein 1", "protein_names_refseq": "ethanol metabolism protein", "tax_id": 559292, "disease": "mitochondrial DNA depletion syndrome (Disease Ontology:DOID:0070329); mitochondrial DNA depletion syndrome 3 (Disease Ontology:DOID:0080121); mitochondrial DNA depletion syndrome 6 (Disease Ontology:DOID:0080125); Alport syndrome 2 (Disease Ontology:DOID:0110033); Charcot-Marie-Tooth disease type 2EE (Disease Ontology:DOID:0111559); nephrotic syndrome (Disease Ontology:DOID:1184); mitochondrial metabolism disease (Disease Ontology:DOID:700)", "pathway": " (sce:YLR251W); (R-SCE-9033241)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "14562106;15189984;16582910;17322287;24374639;9169871", "class_list": "", "function": "May be involved in cellular response to stress. Required to maintain mitochondrial DNA (mtDNA) integrity and stability. Required for ethanol metabolism and tolerance during heat shock., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYP9", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006067 ethanol metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q06563-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06567-1", "uniprot_id": "MCP2_YEAST", "mass": 65917.0, "length": 569, "protein_name": "ABC1 family protein MCP2", "gene_name": "MCP2", "organism": "Yeast", "refseq_name": "Cqd2p", "refseq_ac": "NP_013354", "gene_names_uniprotkb": "MCP2; L9672.2; MRX13", "gene_names_refseq": "CQD2; MCP2; MRX13", "protein_names_uniprotkb": "ABC1 family protein MCP2; MDM10-complementing protein 2; MIOREX complex component 13; Mitochondrial organization of gene expression protein 13", "protein_names_refseq": "Cqd2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR253W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562095;14562106;16823961;23781023;24374639;25683707;9169871", "class_list": "", "function": "Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression (PubMed:25683707). Involved in mitochondrial lipid homeostasis (PubMed:23781023)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYQ0", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0055088 lipid homeostasis;GO:0007005 mitochondrion organization", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q06567-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06568-1", "uniprot_id": "NDE1_YEAST", "mass": 21530.0, "length": 189, "protein_name": "Nuclear distribution protein nudE homolog 1", "gene_name": "NDL1", "organism": "Yeast", "refseq_name": "Ndl1p", "refseq_ac": "NP_013355", "gene_names_uniprotkb": "NDL1", "gene_names_refseq": "NDL1", "protein_names_uniprotkb": "Nuclear distribution protein nudE homolog 1; Nuclear distribution protein nudE-like 1", "protein_names_refseq": "Ndl1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR254C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "15965467;17322287;24374639;33229814;9169871", "class_list": "", "function": "Required for nuclear migration to the bud neck during cell division. Targets cytoplasmic dynein to microtubule plus ends thereby promoting dynein-mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 6, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 6, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 6, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6VYQ1", "ec_number_list": "", "go_molecular_function": "GO:0051010 microtubule plus-end binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005777 peroxisome;GO:0005881 cytoplasmic microtubule", "go_biological_process": "GO:0051301 cell division;GO:0030473 nuclear migration along microtubule", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q06568-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06597-1", "uniprot_id": "ARR2_YEAST", "mass": 14883.0, "length": 130, "protein_name": "Arsenical-resistance protein 2", "gene_name": "ARR2", "organism": "Yeast", "refseq_name": "Arr2p", "refseq_ac": "NP_015526", "gene_names_uniprotkb": "ARR2; ACR2; P9677.16", "gene_names_refseq": "ACR2; ARR2", "protein_names_uniprotkb": "Arsenical-resistance protein 2", "protein_names_refseq": "Arr2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR200C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "17322287;24374639;9169875;9234670", "class_list": "", "function": "Involved in resistance to arsenic compounds., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W4J8", "ec_number_list": "", "go_molecular_function": "GO:0004725 protein tyrosine phosphatase activity;GO:0030611 arsenate reductase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0046685 response to arsenic-containing substance", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q06597-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06616-1", "uniprot_id": "CSA1_YEAST", "mass": 25411.0, "length": 221, "protein_name": "CDC5 pindle pole body anchor protein 1", "gene_name": "CSA1", "organism": "Yeast", "refseq_name": "Csa1p", "refseq_ac": "NP_015500", "gene_names_uniprotkb": "CSA1", "gene_names_refseq": "CSA1", "protein_names_uniprotkb": "CDC5 pindle pole body anchor protein 1; CDC5 SPB anchor protein 1", "protein_names_refseq": "Csa1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR174C)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "14562095;14562106;15282802;17322287;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21177495;22218487;22814378;23749301;24374639;24909858;30516470;32553169;32597660;33481703;33491328;9169875", "class_list": "", "function": "Specialized component of the nuclear membrane that may be involved in the connection of the spindle pole body (SPB) to the nuclear envelope (PubMed:15282802). Recruits CDC5 to spindle pole bodies in metaphase (PubMed:32553169)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 16, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W4H5", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0031965 nuclear membrane;GO:0034399 nuclear periphery;GO:0005816 spindle pole body", "go_biological_process": "GO:1902365 positive regulation of protein localization to spindle pole body", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "Q06616-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06636-1", "uniprot_id": "GPI11_YEAST", "mass": 25262.0, "length": 219, "protein_name": "Glycosylphosphatidylinositol anchor biosynthesis protein 11", "gene_name": "GPI11", "organism": "Yeast", "refseq_name": "mannose-ethanolamine phosphotransferase GPI11", "refseq_ac": "NP_010588", "gene_names_uniprotkb": "GPI11", "gene_names_refseq": "GPI11", "protein_names_uniprotkb": "Glycosylphosphatidylinositol anchor biosynthesis protein 11; PIGF homolog", "protein_names_refseq": "mannose-ethanolamine phosphotransferase GPI11", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR302W); (R-SCE-162710)", "pathway_count": 2, "publication_count": 12, "publication_id_list": "10793139;14562095;16847258;17330950;18407956;19779198;23749301;24374639;32597660;33481703;33491328;9169867", "class_list": "", "function": "Acts in the GPI biosynthetic pathway between GlcNAc-PI synthesis and GPI transfer to protein. Required for the formation of complete GPI precursors CP1 and CP2., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VST1", "ec_number_list": "", "go_molecular_function": "GO:0051377 mannose-ethanolamine phosphotransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006506 GPI anchor biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q06636-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06644-1", "uniprot_id": "PMT7_YEAST", "mass": 77570.0, "length": 662, "protein_name": "Probable dolichyl-phosphate-mannose--protein mannosyltransferase 7", "gene_name": "PMT7", "organism": "Yeast", "refseq_name": "putative dolichyl-phosphate-mannose--protein mannosyltransferase", "refseq_ac": "NP_010593", "gene_names_uniprotkb": "PMT7; D9740.4", "gene_names_refseq": "PMT7", "protein_names_uniprotkb": "Probable dolichyl-phosphate-mannose--protein mannosyltransferase 7; 2.4.1.109", "protein_names_refseq": "putative dolichyl-phosphate-mannose--protein mannosyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR307W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "16847258;24374639;33491328;9169867", "class_list": "", "function": "Probable protein O-mannosyltransferase involved in O-glycosylation which is essential for cell wall rigidity. Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VST6", "ec_number_list": "2.4.1.109", "go_molecular_function": "GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0035269 protein O-linked glycosylation via mannose", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q06644-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06665-1", "uniprot_id": "RAD34_YEAST", "mass": 82043.0, "length": 692, "protein_name": "DNA repair protein RAD34", "gene_name": "RAD34", "organism": "Yeast", "refseq_name": "Rad34p", "refseq_ac": "NP_010600", "gene_names_uniprotkb": "RAD34", "gene_names_refseq": "RAD34", "protein_names_uniprotkb": "DNA repair protein RAD34", "protein_names_refseq": "Rad34p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR314C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562095;14562106;15916602;24374639;9169867", "class_list": "", "function": "Involved in nucleotide excision repair (NER) of damaged ribosomal DNA (rDNA). Required for the repair of the RNA polymerase I-transcribed strand of rDNA., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSU3", "ec_number_list": "", "go_molecular_function": "GO:0003684 damaged DNA binding;GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0071942 XPC complex;GO:0000111 nucleotide-excision repair factor 2 complex", "go_biological_process": "GO:0006298 mismatch repair;GO:0006289 nucleotide-excision repair", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q06665-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06667-1", "uniprot_id": "IPK1_YEAST", "mass": 32918.0, "length": 281, "protein_name": "Inositol-pentakisphosphate 2-kinase", "gene_name": "IPK1", "organism": "Yeast", "refseq_name": "inositol pentakisphosphate 2-kinase", "refseq_ac": "NP_010601", "gene_names_uniprotkb": "IPK1; GSL1", "gene_names_refseq": "GSL1; IPK1", "protein_names_uniprotkb": "Inositol-pentakisphosphate 2-kinase; 2.7.1.158; Inositol-1,3,4,5,6-pentakisphosphate 2-kinase; Ins(1,3,4,5,6)P5 2-kinase; InsP5 2-kinase", "protein_names_refseq": "inositol pentakisphosphate 2-kinase", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR315C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10390371;10960485;17322287;24374639;9169867", "class_list": "", "function": "Has kinase activity and phosphorylates inositol-1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5) to produce 1,2,3,4,5,6-hexakisphosphate (InsP6), also known as phytate., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSU4", "ec_number_list": "2.7.1.158", "go_molecular_function": "GO:0035299 inositol-1,3,4,5,6-pentakisphosphate 2-kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0070481 nuclear-transcribed mRNA catabolic process, non-stop decay;GO:0032958 inositol phosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q06667-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06668-1", "uniprot_id": "OMS1_YEAST", "mass": 55589.0, "length": 471, "protein_name": "Methyltransferase OMS1, mitochondrial", "gene_name": "OMS1", "organism": "Yeast", "refseq_name": "putative RNA methyltransferase", "refseq_ac": "NP_010602", "gene_names_uniprotkb": "OMS1", "gene_names_refseq": "OMS1", "protein_names_uniprotkb": "Methyltransferase OMS1, mitochondrial; 2.1.1.-; OXA1 multicopy suppressor 1", "protein_names_refseq": "putative RNA methyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR316W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "12872006;14562095;14562106;15355998;16823961;18407956;24374639;32597660;9169867", "class_list": "", "function": "Mitochondrial methyltransferase which suppresses respiratory defects caused by OXA1 mutations when overexpressed., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSU5", "ec_number_list": "", "go_molecular_function": "GO:0008168 methyltransferase activity;GO:0008757 S-adenosylmethionine-dependent methyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005740 mitochondrial envelope;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q06668-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06672-1", "uniprot_id": "TSR2_YEAST", "mass": 23713.0, "length": 205, "protein_name": "Pre-rRNA-processing protein TSR2", "gene_name": "TSR2", "organism": "Yeast", "refseq_name": "Tsr2p", "refseq_ac": "NP_013539", "gene_names_uniprotkb": "TSR2", "gene_names_refseq": "TSR2", "protein_names_uniprotkb": "Pre-rRNA-processing protein TSR2; 20S rRNA accumulation protein 2", "protein_names_refseq": "Tsr2p", "tax_id": 559292, "disease": "Diamond-Blackfan anemia 14 with mandibulofacial dysostosis (Disease Ontology:DOID:0111897)", "pathway": " (sce:YLR435W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10688190;12748633;12837249;14562095;14562106;24374639;9169871", "class_list": "", "function": "Required for 20S pre-rRNA processing., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ69", "ec_number_list": "", "go_molecular_function": "GO:0043022 ribosome binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q06672-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06673-1", "uniprot_id": "HID1_YEAST", "mass": 145052.0, "length": 1274, "protein_name": "Protein ECM30", "gene_name": "ECM30", "organism": "Yeast", "refseq_name": "Ecm30p", "refseq_ac": "NP_013540", "gene_names_uniprotkb": "ECM30", "gene_names_refseq": "ECM30", "protein_names_uniprotkb": "Protein ECM30; Extracellular mutant protein 30", "protein_names_refseq": "Ecm30p", "tax_id": 559292, "disease": "developmental and epileptic encephalopathy 105 (Disease Ontology:DOID:0070391)", "pathway": " (sce:YLR436C)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "14562095;14562106;17330950;17563356;18407956;19779198;20702584;21126336;23749301;24374639;32597660;33229814;33481703;33491328;9169871;9335584", "class_list": "", "function": "Required to form the correct cell wall composition., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 8, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 8, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 8, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 31, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ70", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0005797 Golgi medial cisterna;GO:0000138 Golgi trans cisterna", "go_biological_process": "GO:0071555 cell wall organization", "synthesized_glycan_count": 0, "hit_score": 2.6, "record_id": "Q06673-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06678-1", "uniprot_id": "RM35_YEAST", "mass": 42825.0, "length": 367, "protein_name": "Large ribosomal subunit protein mL38", "gene_name": "MRPL35", "organism": "Yeast", "refseq_name": "mitochondrial 54S ribosomal protein mL38 MRPL35", "refseq_ac": "NP_010608", "gene_names_uniprotkb": "MRPL35; D9798.5", "gene_names_refseq": "MRPL35; mL38", "protein_names_uniprotkb": "Large ribosomal subunit protein mL38; 54S ribosomal protein L35, mitochondrial; YmL35", "protein_names_refseq": "mitochondrial 54S ribosomal protein mL38 MRPL35", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR322W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "12392552;12426313;14562095;14562106;14576278;24374639;24675956;25609543;9151978;9169867", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSV4", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0033617 mitochondrial respiratory chain complex IV assembly;GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q06678-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06683-1", "uniprot_id": "IRC3_YEAST", "mass": 78546.0, "length": 689, "protein_name": "Putative ATP-dependent helicase IRC3", "gene_name": "IRC3", "organism": "Yeast", "refseq_name": "double-stranded DNA-dependent ATPase", "refseq_ac": "NP_010619", "gene_names_uniprotkb": "IRC3", "gene_names_refseq": "IRC3", "protein_names_uniprotkb": "Putative ATP-dependent helicase IRC3; 3.6.4.-; Increased recombination centers protein 3", "protein_names_refseq": "double-stranded DNA-dependent ATPase", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR332W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562095;14562106;24374639;33229814;33502312;9169867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VSW4", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0000403 Y-form DNA binding;GO:0061749 forked DNA-dependent helicase activity;GO:0036121 double-stranded DNA helicase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0032042 mitochondrial DNA metabolic process;GO:1905082 regulation of mitochondrial translational elongation", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q06683-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06686-1", "uniprot_id": "CTR3_YEAST", "mass": 27534.0, "length": 241, "protein_name": "Copper transport protein CTR3", "gene_name": "CTR3", "organism": "Yeast", "refseq_name": "high-affinity Cu transporter CTR3", "refseq_ac": "NP_013515", "gene_names_uniprotkb": "CTR3; L9931.6", "gene_names_refseq": "CTR3", "protein_names_uniprotkb": "Copper transport protein CTR3; Copper transporter 3", "protein_names_refseq": "high-affinity Cu transporter CTR3", "tax_id": 559292, "disease": "Wilson disease (Disease Ontology:DOID:893)", "pathway": " (sce:YLR411W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "16847258;17322287;24374639;8756349;9169871", "class_list": "", "function": "Required for high affinity copper (probably reduced Cu I) transport into the cell., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ47", "ec_number_list": "", "go_molecular_function": "GO:0005375 copper ion transmembrane transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0030659 cytoplasmic vesicle membrane", "go_biological_process": "GO:0035434 copper ion transmembrane transport;GO:0015677 copper ion import", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q06686-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06688-1", "uniprot_id": "SRR1L_YEAST", "mass": 31707.0, "length": 274, "protein_name": "SRR1-like protein BER1", "gene_name": "BER1", "organism": "Yeast", "refseq_name": "Ber1p", "refseq_ac": "NP_013516", "gene_names_uniprotkb": "BER1; L9931.5", "gene_names_refseq": "BER1", "protein_names_uniprotkb": "SRR1-like protein BER1; Benomyl resistant protein 1", "protein_names_refseq": "Ber1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR412W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562095;14562106;18064466;23749301;24374639;33491328;9169871", "class_list": "", "function": "Involved in microtubule stability and kinetochore function. May be involved in protein N-terminus acetylation and/or proteasome biogenesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ48", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005874 microtubule", "go_biological_process": "GO:0007017 microtubule-based process", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q06688-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06689-1", "uniprot_id": "YL413_YEAST", "mass": 72698.0, "length": 675, "protein_name": "Cell membrane protein YLR413W", "gene_name": "", "organism": "Yeast", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Cell membrane protein YLR413W", "protein_names_refseq": "", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR413W)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "10601195;12872131;14562095;14562106;15665377;17330950;17563356;18407956;19756047;19779198;20702584;21177495;22106047;22218487;23749301;24374639;32597660;33481703;33491328;9169871", "class_list": "", "function": "", "predicted_glycosites": 18, "predicted_n_glycosites": 18, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 18, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ50", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:0000324 fungal-type vacuole;GO:0051285 cell cortex of cell tip", "go_biological_process": "GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "Q06689-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06698-1", "uniprot_id": "YL419_YEAST", "mass": 163045.0, "length": 1435, "protein_name": "Putative ATP-dependent RNA helicase YLR419W", "gene_name": "", "organism": "Yeast", "refseq_name": "RNA helicase", "refseq_ac": "NP_013523", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Putative ATP-dependent RNA helicase YLR419W; 3.6.4.13", "protein_names_refseq": "RNA helicase", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR419W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "14562095;14562106;18407956;19779198;21126336;23749301;24374639;32597660;33481703;33491328;9169871", "class_list": "", "function": "Probable ATP-binding RNA helicase., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ55", "ec_number_list": "3.6.4.13;5.6.2.3;3.6.4.10;3.6.-.-;5.6.2.4;3.6.4.-;5.6.1.4;3.6.4.12;3.6.4.6;5.6.2.5;3.6.1.-;2.3.2.27;3.1.-.-;3.4.24.-;3.6.5.-;2.7.4.3;2.7.11.1;7.2.2.-", "go_molecular_function": "GO:0003723 RNA binding;GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0004386 helicase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q06698-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06702-1", "uniprot_id": "CDA1_YEAST", "mass": 34642.0, "length": 301, "protein_name": "Chitin deacetylase 1", "gene_name": "CDA1", "organism": "Yeast", "refseq_name": "chitin deacetylase CDA1", "refseq_ac": "NP_013410", "gene_names_uniprotkb": "CDA1; L2142.2", "gene_names_refseq": "CDA1", "protein_names_uniprotkb": "Chitin deacetylase 1; 3.5.1.41", "protein_names_refseq": "chitin deacetylase CDA1", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR307W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "17322287;24374639;9133736;9169871", "class_list": "", "function": "Hydrolyzes the N-acetamido groups of N-acetyl-D-glucosamine residues in chitin to form chitosan and acetate (PubMed:9133736). Chitosan is a component of the spore wall (PubMed:9133736)., [UniProtKB, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "D6VYV0", "ec_number_list": "3.5.1.41", "go_molecular_function": "GO:0046872 metal ion binding;GO:0008061 chitin binding;GO:0004099 chitin deacetylase activity", "go_cellular_component": "GO:0005628 prospore membrane", "go_biological_process": "GO:0000272 polysaccharide catabolic process;GO:0006032 chitin catabolic process;GO:0030476 ascospore wall assembly", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q06702-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06707-1", "uniprot_id": "SWC7_YEAST", "mass": 15121.0, "length": 132, "protein_name": "SWR1-complex protein 7", "gene_name": "SWC7", "organism": "Yeast", "refseq_name": "Swc7p", "refseq_ac": "NP_013489", "gene_names_uniprotkb": "SWC7; AWS1", "gene_names_refseq": "AWS1; SWC7", "protein_names_uniprotkb": "SWR1-complex protein 7", "protein_names_refseq": "Swc7p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR385C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562095;14562106;14690608;15045029;17322287;24374639;9169871", "class_list": "", "function": "Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ20", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0000812 Swr1 complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q06707-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06709-1", "uniprot_id": "REH1_YEAST", "mass": 49690.0, "length": 432, "protein_name": "Cytoplasmic 60S subunit biogenesis factor REH1", "gene_name": "REH1", "organism": "Yeast", "refseq_name": "Reh1p", "refseq_ac": "NP_013491", "gene_names_uniprotkb": "REH1", "gene_names_refseq": "REH1", "protein_names_uniprotkb": "Cytoplasmic 60S subunit biogenesis factor REH1; REI1-homolog 1; pre-60S factor REH1", "protein_names_refseq": "Reh1p", "tax_id": 559292, "disease": "azoospermia (Disease Ontology:DOID:14227)", "pathway": " (sce:YLR387C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "14562095;14562106;17322287;17563356;18407956;19433447;24374639;33481703;33491328;9169871;9171100", "class_list": "", "function": "Pre-60S-associated cytoplasmic factor involved in the cytoplasmic maturation of the 60S subunit. May act redundantly with REI1 to directly promote a stabilizing structural rearrangement in cytoplasmic 60S subunit maturation independent on the REI1-specific ARX1 recycling., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ22;Q7LIF0", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0043023 ribosomal large subunit binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0030687 preribosome, large subunit precursor", "go_biological_process": "GO:0042273 ribosomal large subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q06709-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06815-1", "uniprot_id": "MRL1_YEAST", "mass": 42706.0, "length": 381, "protein_name": "Mannose 6-phosphate receptor-like protein 1", "gene_name": "MRL1", "organism": "Yeast", "refseq_name": "Mrl1p", "refseq_ac": "NP_015404", "gene_names_uniprotkb": "MRL1", "gene_names_refseq": "MRL1", "protein_names_uniprotkb": "Mannose 6-phosphate receptor-like protein 1", "protein_names_refseq": "Mrl1p", "tax_id": 559292, "disease": "non-Hodgkin lymphoma (Disease Ontology:DOID:0060060); colon carcinoma (Disease Ontology:DOID:1520); nephroblastoma (Disease Ontology:DOID:2154); breast carcinoma (Disease Ontology:DOID:3459); hepatocellular carcinoma (Disease Ontology:DOID:684); in situ carcinoma (Disease Ontology:DOID:8719); breast carcinoma in situ (Disease Ontology:DOID:8791); type 2 diabetes mellitus (Disease Ontology:DOID:9352); multiple myeloma (Disease Ontology:DOID:9538); type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": " (sce:YPR079W); (R-SCE-6798695); (R-SCE-8856825)", "pathway_count": 3, "publication_count": 17, "publication_id_list": "11470415;14562095;15665377;17330950;17563356;18407956;19684113;19779198;20702584;21126336;21177495;23749301;24374639;32597660;33481703;33491328;9169875", "class_list": "", "function": "Sorting receptor involved in the transport of vacuolar enzymes from the Golgi complex to the vacuole. Involved in the delivery and maturation of PEP4 (vacuolar proteinase A) and PRB1 (vacuolar proteinase B)., [UniProtKB, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "D6W481", "ec_number_list": "", "go_molecular_function": "GO:0005048 signal sequence binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005770 late endosome;GO:0010008 endosome membrane;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0007034 vacuolar transport;GO:0015031 protein transport", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q06815-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06820-1", "uniprot_id": "MDM36_YEAST", "mass": 64958.0, "length": 579, "protein_name": "Mitochondrial distribution and morphology protein 36", "gene_name": "MDM36", "organism": "Yeast", "refseq_name": "Mdm36p", "refseq_ac": "NP_015408", "gene_names_uniprotkb": "MDM36", "gene_names_refseq": "MDM36", "protein_names_uniprotkb": "Mitochondrial distribution and morphology protein 36", "protein_names_refseq": "Mdm36p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR083W)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "11907266;14562106;18407956;19779198;19795423;19823750;21126336;23749301;24374639;32597660;33481703;33491328;9169875", "class_list": "", "function": "Involved in mitochondrial distribution and morphology., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W485", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0044233 mitochondria-associated endoplasmic reticulum membrane contact site", "go_biological_process": "GO:0007005 mitochondrion organization;GO:0000266 mitochondrial fission;GO:0048312 intracellular distribution of mitochondria;GO:1990456 mitochondrion-endoplasmic reticulum membrane tethering;GO:0000001 mitochondrion inheritance", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q06820-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06822-1", "uniprot_id": "ASA1_YEAST", "mass": 50563.0, "length": 443, "protein_name": "ASTRA-associated protein 1", "gene_name": "ASA1", "organism": "Yeast", "refseq_name": "Asa1p", "refseq_ac": "NP_015410", "gene_names_uniprotkb": "ASA1", "gene_names_refseq": "ASA1", "protein_names_uniprotkb": "ASTRA-associated protein 1", "protein_names_refseq": "Asa1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR085C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "12748633;19040720;24374639;33481703;33491328;9169875", "class_list": "", "function": "Component of the ASTRA complex involved in chromatin remodeling., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W487", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0110078 TTT Hsp90 cochaperone complex", "go_biological_process": "GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q06822-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06834-1", "uniprot_id": "ASR1_YEAST", "mass": 33347.0, "length": 288, "protein_name": "Alcohol-sensitive RING finger protein 1", "gene_name": "ASR1", "organism": "Yeast", "refseq_name": "ubiquitin-protein ligase ASR1", "refseq_ac": "NP_015418", "gene_names_uniprotkb": "ASR1", "gene_names_refseq": "ASR1", "protein_names_uniprotkb": "Alcohol-sensitive RING finger protein 1", "protein_names_refseq": "ubiquitin-protein ligase ASR1", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR093C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "12748633;15117954;24374639;9169875", "class_list": "", "function": "Required for tolerance to alcohol., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W492", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0045471 response to ethanol;GO:0016567 protein ubiquitination;GO:0000921 septin ring assembly", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q06834-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06835-1", "uniprot_id": "RDS3_YEAST", "mass": 12260.0, "length": 107, "protein_name": "Pre-mRNA-splicing factor RDS3", "gene_name": "RDS3", "organism": "Yeast", "refseq_name": "U2 snRNP complex subunit RDS3", "refseq_ac": "NP_015419", "gene_names_uniprotkb": "RDS3; P9513.2", "gene_names_refseq": "RDS3", "protein_names_uniprotkb": "Pre-mRNA-splicing factor RDS3; Regulator of drug sensitivity 3", "protein_names_refseq": "U2 snRNP complex subunit RDS3", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR094W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "11943786;14517302;17322287;24374639;33491328;9169875", "class_list": "", "function": "Required for pre-mRNA splicing. Involved in regulation of drug sensitivity and may play a role in multidrug resistance., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W493", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005686 U2 snRNP;GO:0071011 precatalytic spliceosome", "go_biological_process": "GO:0009410 response to xenobiotic stimulus;GO:0000398 mRNA splicing, via spliceosome;GO:0000245 spliceosomal complex assembly;GO:1903241 U2-type prespliceosome assembly", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q06835-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06891-1", "uniprot_id": "RAF_YEAST", "mass": 21290.0, "length": 181, "protein_name": "Trans-acting factor D", "gene_name": "RAF1", "organism": "Yeast", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RAF1", "gene_names_refseq": "", "protein_names_uniprotkb": "Trans-acting factor D; RAF; REP-antagonizing factor; Recombinase-activating factor", "protein_names_refseq": "", "tax_id": 559292, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 5, "publication_id_list": "1676387;2832156;28472368;29897761;6251374", "class_list": "", "function": "Plays a role in 2-micron plasmid partitioning. Antagonizes transcriptional repression of recombinase FLP by REP1-REP2 (PubMed:2832156). Regulates both stability and copy number of the plasmid by blocking the formation of the REP1-REP2 repressor complex (PubMed:28472368)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q06966;Q06977", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006276 plasmid maintenance;GO:0030541 plasmid partitioning", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q06891-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06892-1", "uniprot_id": "POS5_YEAST", "mass": 46247.0, "length": 414, "protein_name": "NADH kinase POS5, mitochondrial", "gene_name": "POS5", "organism": "Yeast", "refseq_name": "NADH kinase", "refseq_ac": "NP_015136", "gene_names_uniprotkb": "POS5", "gene_names_refseq": "POS5", "protein_names_uniprotkb": "NADH kinase POS5, mitochondrial; 2.7.1.86", "protein_names_refseq": "NADH kinase", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL188W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "12727869;12912900;14562095;14562106;16823961;24374639;2547755;33491328;9169875", "class_list": "", "function": "Phosphorylates both NADH and NAD(+), with a twofold preference for NADH. Anti-oxidant factor and key source of the cellular reductant NADPH., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3I1;Q08928", "ec_number_list": "2.7.1.86", "go_molecular_function": "GO:0003951 NAD+ kinase activity;GO:0005524 ATP binding;GO:0042736 NADH kinase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0016226 iron-sulfur cluster assembly;GO:0006741 NADP+ biosynthetic process;GO:0019674 NAD+ metabolic process;GO:0034599 cellular response to oxidative stress", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q06892-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06991-1", "uniprot_id": "PUN1_YEAST", "mass": 29251.0, "length": 263, "protein_name": "Protein PUN1", "gene_name": "PUN1", "organism": "Yeast", "refseq_name": "Pun1p", "refseq_ac": "NP_013518", "gene_names_uniprotkb": "PUN1", "gene_names_refseq": "PUN1", "protein_names_uniprotkb": "Protein PUN1; Plasma membrane protein up-regulated during nitrogen stress 1", "protein_names_refseq": "Pun1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR414C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "14557538;14562095;14562106;15116342;16000714;16847258;17322287;18799621;19756047;20228058;22106047;24374639;9169871", "class_list": "", "function": "Contributes to the wild-type cellular response to nitrogen stress through signaling pathways that regulate the expression of genes involved in amino acid biosynthesis. Required for wild-type filamentous growth, cell growth, and cell-cell adhesion., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ51;Q6B322", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:0005933 cellular bud", "go_biological_process": "GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q06991-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07349-1", "uniprot_id": "MRX9_YEAST", "mass": 48312.0, "length": 420, "protein_name": "MIOREX complex component 9", "gene_name": "MRX9", "organism": "Yeast", "refseq_name": "Mrx9p", "refseq_ac": "NP_010257", "gene_names_uniprotkb": "MRX9; D2800", "gene_names_refseq": "MRX9", "protein_names_uniprotkb": "MIOREX complex component 9; Mitochondrial organization of gene expression protein 9", "protein_names_refseq": "Mrx9p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL027C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562095;14562106;16823961;24374639;25683707;9046088;9169867", "class_list": "", "function": "Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRW5;Q05321;Q05435;Q7LHC7", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005783 endoplasmic reticulum", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q07349-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07351-1", "uniprot_id": "STP4_YEAST", "mass": 54367.0, "length": 490, "protein_name": "Zinc finger protein STP4", "gene_name": "STP4", "organism": "Yeast", "refseq_name": "Stp4p", "refseq_ac": "NP_010235", "gene_names_uniprotkb": "STP4; D2690", "gene_names_refseq": "STP4", "protein_names_uniprotkb": "Zinc finger protein STP4", "protein_names_refseq": "Stp4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL048C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "14562095;14562106;17563356;19779198;21177495;23749301;24374639;33481703;33491328;9046088;9169867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRU7;P87336;Q05422;Q7LGT2;Q7LH06", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q07351-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07362-1", "uniprot_id": "PBP4_YEAST", "mass": 19881.0, "length": 185, "protein_name": "Protein PBP4", "gene_name": "PBP4", "organism": "Yeast", "refseq_name": "Pbp4p", "refseq_ac": "NP_010230", "gene_names_uniprotkb": "PBP4; D2574", "gene_names_refseq": "PBP4", "protein_names_uniprotkb": "Protein PBP4; PBP1-binding protein 4", "protein_names_refseq": "Pbp4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL053C)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "14562095;14562106;15121841;16702403;17563356;19779198;20471941;22814378;23749301;24374639;32597660;33481703;33491328;34965436;9169867", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VRU3", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005777 peroxisome;GO:0010494 cytoplasmic stress granule", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q07362-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07376-1", "uniprot_id": "MCH1_YEAST", "mass": 53566.0, "length": 486, "protein_name": "Probable transporter MCH1", "gene_name": "MCH1", "organism": "Yeast", "refseq_name": "Mch1p", "refseq_ac": "NP_010229", "gene_names_uniprotkb": "MCH1", "gene_names_refseq": "MCH1", "protein_names_uniprotkb": "Probable transporter MCH1; Monocarboxylate transporter homolog 1", "protein_names_refseq": "Mch1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL054C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "11536335;14562095;16847258;18407956;21126336;23749301;24374639;32597660;33481703;33491328;9169867", "class_list": "", "function": "Probable transporter. Does not act in the transport of monocarboxylic acids across the plasma membrane., [UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VRU2", "ec_number_list": "", "go_molecular_function": "GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0000329 fungal-type vacuole membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q07376-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07395-1", "uniprot_id": "SYO1_YEAST", "mass": 70164.0, "length": 620, "protein_name": "Synchronized import protein 1", "gene_name": "SYO1", "organism": "Yeast", "refseq_name": "Syo1p", "refseq_ac": "NP_010220", "gene_names_uniprotkb": "SYO1", "gene_names_refseq": "SYO1", "protein_names_uniprotkb": "Synchronized import protein 1; Symportin 1", "protein_names_refseq": "Syo1p", "tax_id": 559292, "disease": "Diamond-Blackfan anemia (Disease Ontology:DOID:1339)", "pathway": " (sce:YDL063C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562095;14562106;23118189;23749301;24374639;32597660;33491328;37291423;9169867", "class_list": "", "function": "Nuclear import adapter that specifically recruits the two functionally and topologically linked ribosomal proteins RPL5 and RPL11 (encoded by RPL11A and RPL11B). Guarantees that this cargo pair remains bound together from the time of synthesis in the cytoplasm until delivery to the nascent 5S rRNA in the nucleus., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRT4;P89893;Q7LGT0", "ec_number_list": "", "go_molecular_function": "GO:0051082 unfolded protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0042273 ribosomal large subunit biogenesis;GO:0006606 protein import into nucleus", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q07395-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07451-1", "uniprot_id": "YET3_YEAST", "mass": 22903.0, "length": 203, "protein_name": "Endoplasmic reticulum transmembrane protein 3", "gene_name": "YET3", "organism": "Yeast", "refseq_name": "Yet3p", "refseq_ac": "NP_010211", "gene_names_uniprotkb": "YET3", "gene_names_refseq": "YET3", "protein_names_uniprotkb": "Endoplasmic reticulum transmembrane protein 3", "protein_names_refseq": "Yet3p", "tax_id": 559292, "disease": "deafness, dystonia, and cerebral hypomyelination (Disease Ontology:DOID:0112123); sensorineural hearing loss (Disease Ontology:DOID:10003)", "pathway": " (sce:YDL072C); (R-SCE-75153)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "14562095;14562106;16847258;17322287;21126336;23749301;24374639;32597660;33491328;9169867", "class_list": "", "function": "May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in invertase secretion., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRS7;P89895;Q7LGS8", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0070973 protein localization to endoplasmic reticulum exit site", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q07451-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07458-1", "uniprot_id": "RXT3_YEAST", "mass": 33812.0, "length": 294, "protein_name": "Transcriptional regulatory protein RXT3", "gene_name": "RXT3", "organism": "Yeast", "refseq_name": "Rxt3p", "refseq_ac": "NP_010207", "gene_names_uniprotkb": "RXT3", "gene_names_refseq": "RXT3", "protein_names_uniprotkb": "Transcriptional regulatory protein RXT3", "protein_names_refseq": "Rxt3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL076C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562095;14562106;16314178;22814378;24374639;33481703;33491328;9169867", "class_list": "", "function": "Component of the RPD3C(L) histone deacetylase complex (HDAC) responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRS3", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0070210 Rpd3L-Expanded complex;GO:0033698 Rpd3L complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006334 nucleosome assembly;GO:0016479 negative regulation of transcription by RNA polymerase I", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q07458-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07500-1", "uniprot_id": "NDH2_YEAST", "mass": 61659.0, "length": 545, "protein_name": "External NADH-ubiquinone oxidoreductase 2, mitochondrial", "gene_name": "NDE2", "organism": "Yeast", "refseq_name": "NADH-ubiquinone reductase (H(+)-translocating) NDE2", "refseq_ac": "NP_010198", "gene_names_uniprotkb": "NDE2; NDH2", "gene_names_refseq": "NDE2; NDH2", "protein_names_uniprotkb": "External NADH-ubiquinone oxidoreductase 2, mitochondrial; 1.6.5.9; External NADH dehydrogenase 2", "protein_names_refseq": "NADH-ubiquinone reductase (H(+)-translocating) NDE2", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL085W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10781551;11502169;11713283;12032156;14576278;19795423;19823750;24374639;24440502;9169867;9733747", "class_list": "", "function": "External NADH dehydrogenase required for optimum cellular growth with a number of nonfermentable carbon sources, including ethanol. With NDE1, performes the mitochondrial oxidation of cytosolic NADH under these growth conditions. Regulates the mitochondrial glycerol-3-phosphate dehydrogenase, GUT2, also involved in cytosolic NADH oxidation., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VRR4", "ec_number_list": "1.6.5.9", "go_molecular_function": "GO:0003954 NADH dehydrogenase activity;GO:0016491 oxidoreductase activity;GO:0120555 NADH dehydrogenase (ubiquinone) (non-electrogenic) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005758 mitochondrial intermembrane space", "go_biological_process": "GO:0019655 glycolytic fermentation to ethanol", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q07500-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07527-1", "uniprot_id": "TRM3_YEAST", "mass": 165048.0, "length": 1436, "protein_name": "tRNA (guanosine(18)-2'-O)-methyltransferase", "gene_name": "TRM3", "organism": "Yeast", "refseq_name": "tRNA (guanosine(18)-2'-O)-methyltransferase", "refseq_ac": "NP_010171", "gene_names_uniprotkb": "TRM3", "gene_names_refseq": "TRM3", "protein_names_uniprotkb": "tRNA (guanosine(18)-2'-O)-methyltransferase; 2.1.1.34; tRNA [Gm18] ribose methylase; tRNA methyltransferase 3", "protein_names_refseq": "tRNA (guanosine(18)-2'-O)-methyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL112W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562095;14562106;19779198;23749301;24374639;32053677;33491328;8923743;9169867;9917067", "class_list": "", "function": "S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 18 (Gm18) in various tRNAs., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRN8;P89896;Q05336;Q7LGS3", "ec_number_list": "2.1.1.34", "go_molecular_function": "GO:0016423 tRNA (guanine) methyltransferase activity;GO:0003723 RNA binding;GO:0141100 tRNA (guanine(18)-2'-O)-methyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0002128 tRNA nucleoside ribose methylation;GO:0034599 cellular response to oxidative stress;GO:0030488 tRNA methylation", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q07527-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07534-1", "uniprot_id": "S2538_YEAST", "mass": 34204.0, "length": 307, "protein_name": "Mitochondrial glycine transporter", "gene_name": "HEM25", "organism": "Yeast", "refseq_name": "Hem25p", "refseq_ac": "NP_010164", "gene_names_uniprotkb": "HEM25", "gene_names_refseq": "HEM25", "protein_names_uniprotkb": "Mitochondrial glycine transporter; Heme biosynthesis protein of SLC25 family; Solute carrier family 25 member 38 homolog", "protein_names_refseq": "Hem25p", "tax_id": 559292, "disease": "autosomal recessive pyridoxine-refractory sideroblastic anemia 2 (Disease Ontology:DOID:0060065); sideroblastic anemia (Disease Ontology:DOID:8955)", "pathway": " (sce:YDL119C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10930523;14562095;14562106;16823961;17322287;19412178;24374639;25957689;26821380;27476175;9169867;9178508", "class_list": "", "function": "Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix., [UniProtKB, PubMed, PubMed, PubMed, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRN1", "ec_number_list": "", "go_molecular_function": "GO:0015187 glycine transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006783 heme biosynthetic process;GO:1904983 glycine import into mitochondrion", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q07534-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07541-1", "uniprot_id": "EXP1_YEAST", "mass": 16947.0, "length": 149, "protein_name": "ER export of PMA1 protein 1", "gene_name": "EXP1", "organism": "Yeast", "refseq_name": "Exp1p", "refseq_ac": "NP_010162", "gene_names_uniprotkb": "EXP1", "gene_names_refseq": "EXP1", "protein_names_uniprotkb": "ER export of PMA1 protein 1", "protein_names_refseq": "Exp1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL121C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "14562095;14562106;17322287;19779198;21126336;23749301;24374639;28727280;30516470;33229814;33481703;33491328;9169867", "class_list": "", "function": "Specific cargo receptor protein for the plasma membrane ATPase PMA1 that acts with PSG1 to promote the transport and maturation of PMA1 (PubMed:28727280). EXP1 and PSG1 probably act sequentially to promote PMA1 sorting between the ER and the Golgi, with EXP1 promoting PMA1 export from the ER to the Golgi while PSG1 has a role in PMA1 maturation or quality control in the Golgi (PubMed:28727280)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 6, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 6, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 6, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6VRM9", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0012507 ER to Golgi transport vesicle membrane;GO:0030663 COPI-coated vesicle membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "Q07541-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07623-1", "uniprot_id": "NOP6_YEAST", "mass": 25216.0, "length": 225, "protein_name": "Nucleolar protein 6", "gene_name": "NOP6", "organism": "Yeast", "refseq_name": "Nop6p", "refseq_ac": "NP_010068", "gene_names_uniprotkb": "NOP6; D1018", "gene_names_refseq": "NOP6", "protein_names_uniprotkb": "Nucleolar protein 6", "protein_names_refseq": "Nop6p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL213C)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "14562095;14562106;14566057;17322287;18407956;19779198;19795423;19823750;23749301;24374639;30516470;32597660;33481703;33491328;9046097;9169867", "class_list": "", "function": "Predicted to be involved in rRNA processing., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRE1", "ec_number_list": "", "go_molecular_function": "GO:0030515 snoRNA binding;GO:0019843 rRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0030686 90S preribosome", "go_biological_process": "GO:0006364 rRNA processing;GO:0042274 ribosomal small subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q07623-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07651-1", "uniprot_id": "FMP45_YEAST", "mass": 34135.0, "length": 309, "protein_name": "SUR7 family protein FMP45", "gene_name": "FMP45", "organism": "Yeast", "refseq_name": "Fmp45p", "refseq_ac": "NP_010059", "gene_names_uniprotkb": "FMP45", "gene_names_refseq": "FMP45", "protein_names_uniprotkb": "SUR7 family protein FMP45", "protein_names_refseq": "Fmp45p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL222C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "11784867;11875433;12868060;14562095;14562106;17078969;17334841;19779198;19795423;19823750;24374639;33491328;9169867", "class_list": "", "function": "Involved in sporulation and affects the sphingolipid composition of the plasma membrane., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VRD3", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0045121 membrane raft;GO:0071944 cell periphery", "go_biological_process": "GO:0006897 endocytosis;GO:0030866 cortical actin cytoskeleton organization;GO:0032185 septin cytoskeleton organization;GO:0030437 ascospore formation;GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q07651-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07653-1", "uniprot_id": "HBT1_YEAST", "mass": 113616.0, "length": 1046, "protein_name": "Protein HBT1", "gene_name": "HBT1", "organism": "Yeast", "refseq_name": "Hbt1p", "refseq_ac": "NP_010058", "gene_names_uniprotkb": "HBT1; Crem", "gene_names_refseq": "HBT1", "protein_names_uniprotkb": "Protein HBT1; HUB1 target protein 1", "protein_names_refseq": "Hbt1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL223C)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "11875433;11923536;14562095;15456898;15665377;17287358;17330950;17563356;18407956;19779198;19795423;19823750;20702584;21126336;21177495;22218487;24374639;30516470;32597660;33229814;33481703;33491328;9169867", "class_list": "", "function": "Polarity-determining protein which forms a conjugate with the ubiquitin-like modifier HUB1. Involved in bud site selection and cellular morphogenesis during conjugation. Required for survival during stationary phase., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 16, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 16, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 16, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 75, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 16, "binding_glycan_count": 0, "secondary_ac_list": "D6VRD2", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005937 mating projection", "go_biological_process": "GO:0008360 regulation of cell shape;GO:0000753 cell morphogenesis involved in conjugation with cellular fusion", "synthesized_glycan_count": 0, "hit_score": 4.1, "record_id": "Q07653-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07655-1", "uniprot_id": "WHI4_YEAST", "mass": 70690.0, "length": 649, "protein_name": "Protein WHI4", "gene_name": "WHI4", "organism": "Yeast", "refseq_name": "Whi4p", "refseq_ac": "NP_010057", "gene_names_uniprotkb": "WHI4; D0839", "gene_names_refseq": "WHI4", "protein_names_uniprotkb": "Protein WHI4", "protein_names_refseq": "Whi4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL224C)", "pathway_count": 1, "publication_count": 21, "publication_id_list": "11290704;14562095;15665377;16172400;16278933;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21177495;23749301;24374639;30516470;32597660;33229814;33481703;33491328;9169867", "class_list": "", "function": "Has a partially redundant function to WHI3, a dosage-dependent modulator of cell size., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 13, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 13, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 13, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 29, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 12, "binding_glycan_count": 0, "secondary_ac_list": "D6VRD1", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0061157 mRNA destabilization;GO:0008361 regulation of cell size", "synthesized_glycan_count": 0, "hit_score": 3.6, "record_id": "Q07655-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07660-1", "uniprot_id": "BRE4_YEAST", "mass": 129725.0, "length": 1125, "protein_name": "Protein BRE4", "gene_name": "BRE4", "organism": "Yeast", "refseq_name": "Bre4p", "refseq_ac": "NP_010050", "gene_names_uniprotkb": "BRE4", "gene_names_refseq": "BRE4", "protein_names_uniprotkb": "Protein BRE4; Brefeldin A-sensitivity protein 4", "protein_names_refseq": "Bre4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL231C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "11169758;16847258;17287358;19684113;23749301;24374639;33481703;33491328;9169867", "class_list": "", "function": "May be involved in intracellular vesicle transport., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VRC5", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0006897 endocytosis;GO:0015031 protein transport", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q07660-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07684-1", "uniprot_id": "MFG1_YEAST", "mass": 51320.0, "length": 458, "protein_name": "Morphogenetic regulator of filamentous growth protein 1", "gene_name": "MFG1", "organism": "Yeast", "refseq_name": "Mfg1p", "refseq_ac": "NP_010048", "gene_names_uniprotkb": "MFG1", "gene_names_refseq": "MFG1", "protein_names_uniprotkb": "Morphogenetic regulator of filamentous growth protein 1", "protein_names_refseq": "Mfg1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL233W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "14562095;14562106;18407956;21126336;22984072;23749301;24374639;32597660;33481703;33491328;9169867", "class_list": "", "function": "Transcriptional regulator with a general role in all morphogenetically distinct forms of filamentous growth, namely haploid invasive growth, biofilm formation, and diploid pseudohyphal growth. May control FLO11 gene expression as part of a promoter-bound complex with FLO8 and MSS1., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRC3", "ec_number_list": "", "go_molecular_function": "GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q07684-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07729-1", "uniprot_id": "GUAD_YEAST", "mass": 55204.0, "length": 489, "protein_name": "Probable guanine deaminase", "gene_name": "GUD1", "organism": "Yeast", "refseq_name": "guanine deaminase", "refseq_ac": "NP_010043", "gene_names_uniprotkb": "GUD1", "gene_names_refseq": "GUD1", "protein_names_uniprotkb": "Probable guanine deaminase; 3.5.4.3; GAH; Guanase; Guanine aminase; Guanine aminohydrolase", "protein_names_refseq": "guanine deaminase", "tax_id": 559292, "disease": "stomach cancer (Disease Ontology:DOID:10534)", "pathway": " (sce:YDL238C); (R-SCE-74259)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "14562095;14562106;15565584;24374639;33491328;9169867", "class_list": "", "function": "Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRB8", "ec_number_list": "3.5.4.3", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0008892 guanine deaminase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0046098 guanine metabolic process;GO:0006147 guanine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q07729-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07786-1", "uniprot_id": "DHSO2_YEAST", "mass": 38097.0, "length": 357, "protein_name": "Sorbitol dehydrogenase 2", "gene_name": "SOR2", "organism": "Yeast", "refseq_name": "L-iditol 2-dehydrogenase SOR2", "refseq_ac": "NP_010035", "gene_names_uniprotkb": "SOR2", "gene_names_refseq": "SOR2", "protein_names_uniprotkb": "Sorbitol dehydrogenase 2; 1.1.1.-; 1.1.1.9; Polyol dehydrogenase; SDH 2; Xylitol dehydrogenase", "protein_names_refseq": "L-iditol 2-dehydrogenase SOR2", "tax_id": 559292, "disease": "autosomal recessive distal hereditary motor neuronopathy 8 (Disease Ontology:DOID:0081427); cataract (Disease Ontology:DOID:83); diabetic neuropathy (Disease Ontology:DOID:9743)", "pathway": " (sce:YDL246C); (R-SCE-5652227); (R-SCE-5661270)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "24374639;9169867", "class_list": "", "function": "Polyol dehydrogenase that catalyzes the reversible NAD(+)-dependent oxidation of various sugar alcohols. Is active with D-sorbitol (D-glucitol) and xylitol as substrates, leading to the C2-oxidized product D-fructose and D-xylulose, respectively., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VRB1", "ec_number_list": "1.1.1.-;1.1.1.9", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003939 L-iditol 2-dehydrogenase (NAD+) activity;GO:0046526 D-xylulose reductase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0019318 hexose metabolic process;GO:0046370 fructose biosynthetic process;GO:0006062 sorbitol catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q07786-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07788-1", "uniprot_id": "COS7_YEAST", "mass": 45680.0, "length": 383, "protein_name": "Protein COS7", "gene_name": "COS7", "organism": "Yeast", "refseq_name": "Cos7p", "refseq_ac": "NP_010033", "gene_names_uniprotkb": "COS7", "gene_names_refseq": "COS7", "protein_names_uniprotkb": "Protein COS7", "protein_names_refseq": "Cos7p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL248W)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "16847258;24374639;9169867", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRA9", "ec_number_list": "", "go_molecular_function": "GO:0038024 cargo receptor activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005768 endosome;GO:0016020 membrane;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q07788-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07798-1", "uniprot_id": "SPO75_YEAST", "mass": 102170.0, "length": 868, "protein_name": "Sporulation-specific protein 75", "gene_name": "SPO75", "organism": "Yeast", "refseq_name": "Spo75p", "refseq_ac": "NP_013096", "gene_names_uniprotkb": "SPO75; L1361", "gene_names_refseq": "SPO75", "protein_names_uniprotkb": "Sporulation-specific protein 75", "protein_names_refseq": "Spo75p", "tax_id": 559292, "disease": "hypomyelinating leukodystrophy 19 (Disease Ontology:DOID:0070400)", "pathway": " (sce:YLL005C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "11470404;15590821;16847258;24374639;33491328;8810043;9169871", "class_list": "", "function": "Acts as an osmosensitive calcium-permeable cation channel (By similarity). Required for spore wall assembly and ascus formation., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VXZ8", "ec_number_list": "", "go_molecular_function": "GO:0005227 calcium-activated cation channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0030437 ascospore formation;GO:0030476 ascospore wall assembly", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q07798-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07799-1", "uniprot_id": "LMO1_YEAST", "mass": 76622.0, "length": 665, "protein_name": "ELMO family protein LMO1", "gene_name": "LMO1", "organism": "Yeast", "refseq_name": "Lmo1p", "refseq_ac": "NP_013094", "gene_names_uniprotkb": "LMO1; L1353", "gene_names_refseq": "LMO1", "protein_names_uniprotkb": "ELMO family protein LMO1", "protein_names_refseq": "Lmo1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLL007C)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "14562095;14562106;17563356;18407956;20702584;21126336;23749301;24374639;25598154;32597660;33481703;33491328;8810043;9169871", "class_list": "", "function": "Forms a transiant heterodimeric complex with DCK1, that acts as a guanine nucleotide exchange factor (GEF) for the small GTPase RHO5 (PubMed:25598154). DCK1, LMO1 and RHO5 relocate to mitochondria upon oxidative stress and trigger cell death (PubMed:25598154). The DCK1/LMO1/RHO5 signaling module mediates mitochondrial turnover under nitrogen starvation conditions via mitophagy (PubMed:25598154). The DCK1/LMO1/RHO5 signaling module also plays a role in cell wall integrity signaling (PubMed:25598154)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXZ5;E9PAG4", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005886 plasma membrane", "go_biological_process": "GO:0007015 actin filament organization;GO:0035556 intracellular signal transduction;GO:0048870 cell motility;GO:0000422 autophagy of mitochondrion", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q07799-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07825-1", "uniprot_id": "FRA1_YEAST", "mass": 84924.0, "length": 749, "protein_name": "Putative Xaa-Pro aminopeptidase FRA1", "gene_name": "FRA1", "organism": "Yeast", "refseq_name": "aminopeptidase P", "refseq_ac": "NP_013071", "gene_names_uniprotkb": "FRA1", "gene_names_refseq": "FRA1", "protein_names_uniprotkb": "Putative Xaa-Pro aminopeptidase FRA1; 3.4.11.9; Fe repressor of activation 1", "protein_names_refseq": "aminopeptidase P", "tax_id": 559292, "disease": "acquired angioedema (Disease Ontology:DOID:0080941)", "pathway": " (sce:YLL029W); (R-SCE-163125)", "pathway_count": 2, "publication_count": 15, "publication_id_list": "14562095;14562106;17563356;18281282;18407956;19779198;20702584;23749301;24374639;30516470;32597660;33229814;33481703;33491328;9169871", "class_list": "", "function": "Involved in the regulation of the iron regulon in responss to decreased mitochondrial iron-sulfur cluster synthesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 7, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 7, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 7, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "D6VXX5", "ec_number_list": "3.1.3.1;3.1.3.54;3.1.7.6;3.4.11.9", "go_molecular_function": "GO:0046872 metal ion binding;GO:0070006 metalloaminopeptidase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006508 proteolysis;GO:0071281 cellular response to iron ion", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "Q07825-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07843-1", "uniprot_id": "IRC19_YEAST", "mass": 27378.0, "length": 230, "protein_name": "Increased recombination centers protein 19", "gene_name": "IRC19", "organism": "Yeast", "refseq_name": "Irc19p", "refseq_ac": "NP_013067", "gene_names_uniprotkb": "IRC19; RRG4", "gene_names_refseq": "IRC19; RRG4", "protein_names_uniprotkb": "Increased recombination centers protein 19; Respiratory growth protein 4", "protein_names_refseq": "Irc19p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLL033W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "11921089;12432101;17322287;18085829;19751518;24374639;9169871;9784122", "class_list": "", "function": "Involved in sporulation and maintenance of the mitochondrial DNA. Is probably involved in a pathway contributing to genomic integrity., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXX2", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0006312 mitotic recombination;GO:0006302 double-strand break repair;GO:0030437 ascospore formation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q07843-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07844-1", "uniprot_id": "RIX7_YEAST", "mass": 93069.0, "length": 837, "protein_name": "Ribosome biogenesis ATPase RIX7", "gene_name": "RIX7", "organism": "Yeast", "refseq_name": "putative AAA family ATPase RIX7", "refseq_ac": "NP_013066", "gene_names_uniprotkb": "RIX7", "gene_names_refseq": "RIX7", "protein_names_uniprotkb": "Ribosome biogenesis ATPase RIX7", "protein_names_refseq": "putative AAA family ATPase RIX7", "tax_id": 559292, "disease": "", "pathway": " (sce:YLL034C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "11447111;14562106;14690591;17330950;18407956;19779198;23749301;24374639;32597660;33481703;33491328;9169871", "class_list": "", "function": "Involved in ribosome biogenesis. Seems to be required for restructuring nucleoplasmic 60S pre-ribosomal particles to make them competent for nuclear export., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXX1", "ec_number_list": "", "go_molecular_function": "GO:1990275 preribosome binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0030687 preribosome, large subunit precursor", "go_biological_process": "GO:0000055 ribosomal large subunit export from nucleus;GO:0042273 ribosomal large subunit biogenesis;GO:0042254 ribosome biogenesis", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q07844-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07872-1", "uniprot_id": "ENT4_YEAST", "mass": 28271.0, "length": 247, "protein_name": "Epsin-4", "gene_name": "ENT4", "organism": "Yeast", "refseq_name": "Ent4p", "refseq_ac": "NP_013062", "gene_names_uniprotkb": "ENT4", "gene_names_refseq": "ENT4", "protein_names_uniprotkb": "Epsin-4", "protein_names_refseq": "Ent4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLL038C); (R-SCE-8856825)", "pathway_count": 2, "publication_count": 13, "publication_id_list": "14562106;17322287;19779198;20702584;21177495;23749301;24374639;30516470;32597660;33229814;33481703;33491328;9169871", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 6, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 6, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 6, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6VXW8", "ec_number_list": "", "go_molecular_function": "GO:0005543 phospholipid binding;GO:0030276 clathrin binding", "go_cellular_component": "GO:0030125 clathrin vesicle coat;GO:0005768 endosome;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0030479 actin cortical patch", "go_biological_process": "GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0072659 protein localization to plasma membrane;GO:0000147 actin cortical patch assembly", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "Q07872-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07888-1", "uniprot_id": "YL067_YEAST", "mass": 154988.0, "length": 1374, "protein_name": "Y' element ATP-dependent helicase YLL067C", "gene_name": "L0111; L0503; L0509", "organism": "Yeast", "refseq_name": "Y' element ATP-dependent helicase", "refseq_ac": "NP_013033", "gene_names_uniprotkb": "L0111; L0503; L0509", "gene_names_refseq": "", "protein_names_uniprotkb": "Y' element ATP-dependent helicase YLL067C; 5.6.2.-", "protein_names_refseq": "Y' element ATP-dependent helicase", "tax_id": 559292, "disease": "", "pathway": " (sce:YLL067C)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "24374639;9169871;9837911", "class_list": "", "function": "Catalyzes DNA unwinding and is involved in telomerase-independent telomere maintenance., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXU2;E9PAE6;O94145;Q12054", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003676 nucleic acid binding;GO:0004386 helicase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0000722 telomere maintenance via recombination", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q07888-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07897-1", "uniprot_id": "CMS1_YEAST", "mass": 33394.0, "length": 291, "protein_name": "Protein CMS1", "gene_name": "CMS1", "organism": "Yeast", "refseq_name": "Cms1p", "refseq_ac": "NP_013103", "gene_names_uniprotkb": "CMS1", "gene_names_refseq": "CMS1", "protein_names_uniprotkb": "Protein CMS1; Complementation of MCM10 suppressor protein 1", "protein_names_refseq": "Cms1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR003C)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "11787774;14562095;14562106;17287358;17563356;18407956;19795423;19823750;20702584;21177495;24374639;30516470;32597660;33481703;33491328;9169871", "class_list": "", "function": "May play a role in the regulation of DNA replication and cell cycle control., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VY05", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0030686 90S preribosome", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q07897-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07904-1", "uniprot_id": "THI73_YEAST", "mass": 58531.0, "length": 523, "protein_name": "Thiamine pathway transporter THI73", "gene_name": "THI73", "organism": "Yeast", "refseq_name": "Thi73p", "refseq_ac": "NP_013104", "gene_names_uniprotkb": "THI73", "gene_names_refseq": "THI73", "protein_names_uniprotkb": "Thiamine pathway transporter THI73", "protein_names_refseq": "Thi73p", "tax_id": 559292, "disease": "neurodegenerative disease (Disease Ontology:DOID:1289); Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (sce:YLR004C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10869563;16194233;16847258;16850348;24374639;9169871", "class_list": "", "function": "Transports either thiamine or, rather, a related metabolite involved in the thiamine biosynthesis pathway., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VY06", "ec_number_list": "", "go_molecular_function": "GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0055085 transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q07904-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07949-1", "uniprot_id": "PSR2_YEAST", "mass": 44772.0, "length": 397, "protein_name": "Probable phosphatase PSR2", "gene_name": "PSR2", "organism": "Yeast", "refseq_name": "putative phosphatase", "refseq_ac": "NP_013119", "gene_names_uniprotkb": "PSR2", "gene_names_refseq": "PSR2", "protein_names_uniprotkb": "Probable phosphatase PSR2; 3.1.3.-; Plasma membrane sodium response protein 2", "protein_names_refseq": "putative phosphatase", "tax_id": 559292, "disease": "lung non-small cell carcinoma (Disease Ontology:DOID:3908)", "pathway": " (sce:YLR019W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10777497;12090248;17322287;19779198;19795423;19823750;20489023;23749301;24374639;30516470;33491328;9169871", "class_list": "", "function": "Probable phosphatase. Involved in the response to sodium and lithium ion stress (but not to potassium or sorbitol stress) by inducing transcription of the sodium pump ENA1/PMR2. Acts through a calcineurin-independent pathway and is functionally redundant with PSR1. Also involved in the general stress response; acts together with WHI2 to activate stress response element (STRE)-mediated gene expression, possibly through dephosphorylation of MSN2., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VY21;Q06898;Q6B1J9", "ec_number_list": "", "go_molecular_function": "GO:0004721 phosphoprotein phosphatase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0034605 cellular response to heat;GO:0009651 response to salt stress;GO:0034198 cellular response to amino acid starvation;GO:1904262 negative regulation of TORC1 signaling", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q07949-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07951-1", "uniprot_id": "POC3_YEAST", "mass": 20061.0, "length": 179, "protein_name": "Proteasome chaperone 3", "gene_name": "IRC25", "organism": "Yeast", "refseq_name": "Irc25p", "refseq_ac": "NP_013121", "gene_names_uniprotkb": "IRC25; DMP2; POC3", "gene_names_refseq": "DMP2; IRC25; PBA3; POC3", "protein_names_uniprotkb": "Proteasome chaperone 3; Increased recombination centers protein 25", "protein_names_refseq": "Irc25p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR021W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562106;17322287;17707236;18278057;24374639;9169871", "class_list": "", "function": "Involved in 20S proteasome assembly, facilitating the alpha-ring formation., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VY23", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0032991 protein-containing complex", "go_biological_process": "GO:0070481 nuclear-transcribed mRNA catabolic process, non-stop decay;GO:0043248 proteasome assembly;GO:0080129 proteasome core complex assembly;GO:0051131 chaperone-mediated protein complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q07951-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07959-1", "uniprot_id": "IZH3_YEAST", "mass": 62571.0, "length": 543, "protein_name": "ADIPOR-like receptor IZH3", "gene_name": "IZH3", "organism": "Yeast", "refseq_name": "Izh3p", "refseq_ac": "NP_013123", "gene_names_uniprotkb": "IZH3", "gene_names_refseq": "IZH3", "protein_names_uniprotkb": "ADIPOR-like receptor IZH3; Implicated in zinc homeostasis protein 3", "protein_names_refseq": "Izh3p", "tax_id": 559292, "disease": "metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); alcohol-associated liver disease (Disease Ontology:DOID:0070658); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); metabolic dysfunction-associated steatohepatitis (Disease Ontology:DOID:0080547); glucose intolerance (Disease Ontology:DOID:10603); breast cancer (Disease Ontology:DOID:1612); hyperinsulinism (Disease Ontology:DOID:2018); prostate adenocarcinoma (Disease Ontology:DOID:2526); hyperglycemia (Disease Ontology:DOID:4195); macular degeneration (Disease Ontology:DOID:4448); end stage renal disease (Disease Ontology:DOID:783); type 2 diabetes mellitus (Disease Ontology:DOID:9352); steatotic liver disease (Disease Ontology:DOID:9452); obesity (Disease Ontology:DOID:9970)", "pathway": " (sce:YLR023C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562095;15060275;24374639;33491328;9169871", "class_list": "", "function": "ADIPOR-like receptor involved in zinc metabolism either by altering membrane sterol content or by directly altering cellular zinc levels., [UniProtKB, PubMed]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 14, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6VY25", "ec_number_list": "", "go_molecular_function": "GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006882 intracellular zinc ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q07959-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07987-1", "uniprot_id": "PAU23_YEAST", "mass": 13178.0, "length": 124, "protein_name": "Seripauperin-23", "gene_name": "PAU23", "organism": "Yeast", "refseq_name": "seripauperin PAU23", "refseq_ac": "NP_013138", "gene_names_uniprotkb": "PAU23; DAN2; L1909", "gene_names_refseq": "DAN2; PAU23", "protein_names_uniprotkb": "Seripauperin-23; Cell wall protein DAN2; Delayed anaerobic protein 2", "protein_names_refseq": "seripauperin PAU23", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR037C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "11160904;11292809;19762443;24374639;9169871", "class_list": "", "function": "Component of the cell wall., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VY40", "ec_number_list": "", "go_molecular_function": "GO:0005199 structural constituent of cell wall", "go_cellular_component": "GO:0000324 fungal-type vacuole;GO:0009277 fungal-type cell wall", "go_biological_process": "GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q07987-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07988-1", "uniprot_id": "AFB1_YEAST", "mass": 24462.0, "length": 224, "protein_name": "A-factor barrier protein 1", "gene_name": "AFB1", "organism": "Yeast", "refseq_name": "Afb1p", "refseq_ac": "NP_013141", "gene_names_uniprotkb": "AFB1", "gene_names_refseq": "AFB1", "protein_names_uniprotkb": "A-factor barrier protein 1", "protein_names_refseq": "Afb1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR040C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10383953;15604142;17322287;24121774;24374639;33491328;9169871", "class_list": "", "function": "MATalpha-specific protein that interferes with a-factor, the pheromone secreted by MATa cells (PubMed:24121774). Contributes to mating efficiency (PubMed:24121774). Acts to bind and sequester a-factor rather than to degrade it, and promotes the efficient mating of MATalpha cells by keeping the a-factor concentration at the plasma membrane within the narrow range needed for accurate pheromone gradient detection (Probable)., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VY43", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0071944 cell periphery;GO:0009277 fungal-type cell wall;GO:0098552 side of membrane", "go_biological_process": "GO:0000749 response to pheromone triggering conjugation with cellular fusion", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q07988-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07990-1", "uniprot_id": "YL042_YEAST", "mass": 16950.0, "length": 161, "protein_name": "Cell wall protein YLR042C", "gene_name": "", "organism": "Yeast", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Cell wall protein YLR042C", "protein_names_refseq": "", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR042C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10383953;14739279;15116342;17322287;24374639;9169871", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VY44", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0071944 cell periphery;GO:0000324 fungal-type vacuole;GO:0009277 fungal-type cell wall;GO:0098552 side of membrane", "go_biological_process": "GO:0060258 negative regulation of filamentous growth", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q07990-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07993-1", "uniprot_id": "XYL2_YEAST", "mass": 38600.0, "length": 356, "protein_name": "D-xylulose reductase", "gene_name": "XYL2", "organism": "Yeast", "refseq_name": "D-xylulose reductase XYL2", "refseq_ac": "NP_013171", "gene_names_uniprotkb": "XYL2", "gene_names_refseq": "XYL2", "protein_names_uniprotkb": "D-xylulose reductase; 1.1.1.9; XDH; Xylitol dehydrogenase", "protein_names_refseq": "D-xylulose reductase XYL2", "tax_id": 559292, "disease": "autosomal recessive distal hereditary motor neuronopathy 8 (Disease Ontology:DOID:0081427); cataract (Disease Ontology:DOID:83); diabetic neuropathy (Disease Ontology:DOID:9743)", "pathway": " (sce:YLR070C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10486580;24374639;33491328;9169871", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VY71", "ec_number_list": "1.1.1.-;1.1.1.9", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0046526 D-xylulose reductase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0042732 D-xylose metabolic process;GO:0046370 fructose biosynthetic process;GO:0005999 xylulose biosynthetic process;GO:0019569 L-arabinose catabolic process to D-xylulose 5-phosphate", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q07993-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08045-1", "uniprot_id": "LCL2_YEAST", "mass": 14922.0, "length": 131, "protein_name": "Long chronological lifespan protein 2", "gene_name": "LCL2", "organism": "Yeast", "refseq_name": "Lcl2p", "refseq_ac": "NP_013205", "gene_names_uniprotkb": "LCL2", "gene_names_refseq": "LCL2", "protein_names_uniprotkb": "Long chronological lifespan protein 2", "protein_names_refseq": "Lcl2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR104W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562106;19325107;20421943;24374639;9169871", "class_list": "", "function": "Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway that acts upstream of HRD3 and USA1., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYA4", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0036503 ERAD pathway", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q08045-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08058-1", "uniprot_id": "COQ10_YEAST", "mass": 23765.0, "length": 207, "protein_name": "Coenzyme Q-binding protein COQ10, mitochondrial", "gene_name": "COQ10", "organism": "Yeast", "refseq_name": "ubiquinone-binding protein COQ10", "refseq_ac": "NP_014635", "gene_names_uniprotkb": "COQ10", "gene_names_refseq": "COQ10", "protein_names_uniprotkb": "Coenzyme Q-binding protein COQ10, mitochondrial", "protein_names_refseq": "ubiquinone-binding protein COQ10", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL008W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "16230336;16823961;17322287;24374639;9169874", "class_list": "", "function": "Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W259", "ec_number_list": "", "go_molecular_function": "GO:0048039 ubiquinone binding;GO:0140104 molecular carrier activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006744 ubiquinone biosynthetic process;GO:0045333 cellular respiration", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q08058-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08119-1", "uniprot_id": "ESC8_YEAST", "mass": 82189.0, "length": 714, "protein_name": "Protein ESC8", "gene_name": "ESC8", "organism": "Yeast", "refseq_name": "Esc8p", "refseq_ac": "NP_014625", "gene_names_uniprotkb": "ESC8", "gene_names_refseq": "ESC8", "protein_names_uniprotkb": "Protein ESC8; Establishes silent chromatin protein 8", "protein_names_refseq": "Esc8p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL017W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "12399377;14562095;14562106;24374639;33491328;9169874", "class_list": "", "function": "Involved in HMR and telomere silencing via the recruitment or stabilizing of the SIR (silent information regulators) complex., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W249", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007062 sister chromatid cohesion;GO:0031507 heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q08119-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08157-1", "uniprot_id": "TOS7_YEAST", "mass": 60901.0, "length": 551, "protein_name": "Uncharacterized membrane protein TOS7", "gene_name": "TOS7", "organism": "Yeast", "refseq_name": "Tos7p", "refseq_ac": "NP_014623", "gene_names_uniprotkb": "TOS7", "gene_names_refseq": "TOS7", "protein_names_uniprotkb": "Uncharacterized membrane protein TOS7", "protein_names_refseq": "Tos7p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL019W)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "14562095;15282802;16847258;19684113;19779198;20702584;21126336;22218487;23749301;24374639;24909858;32597660;33002606;33481703;33491328;9169874", "class_list": "", "function": "Protein involved in secretion and cell wall organization (PubMed:33002606). Contributes to cell surface-related functions as a auxiliary component of MCC/eisosome that specifically interacts with the secretory pathway (PubMed:33002606)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 35, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W247", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0035838 growing cell tip;GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:0005774 vacuolar membrane;GO:0032153 cell division site", "go_biological_process": "GO:0006887 exocytosis", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q08157-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08176-1", "uniprot_id": "MIM1_YEAST", "mass": 12758.0, "length": 113, "protein_name": "Mitochondrial import protein 1", "gene_name": "MIM1", "organism": "Yeast", "refseq_name": "Mim1p", "refseq_ac": "NP_014616", "gene_names_uniprotkb": "MIM1; TOM13", "gene_names_refseq": "MIM1; TOM13", "protein_names_uniprotkb": "Mitochondrial import protein 1; Mitochondrial 13 kDa outer membrane protein", "protein_names_refseq": "Mim1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL026C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "15242642;15326197;15608614;17322287;17974559;18187149;19779198;21825073;21825074;22467864;24374639;9169874", "class_list": "", "function": "Component of the MIM complex required for mitochondrial outer membrane protein import (PubMed:22467864). The MIM complex cooperates with the receptor TOM70 in binding of precursor proteins and promotes their insertion and assembly into the outer membrane (PubMed:21825073). Involved in import of the subset of proteins with multiple alpha-helical transmembrane segments, including UGO1 (PubMed:21825073, PubMed:21825074). Required for the assembly of the TOM (translocase of outer membrane) receptor complex, which is responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins (PubMed:15242642, PubMed:15326197, PubMed:15608614). Required specifically for assembly of TOM40, TOM20, and TOM70, but not TOM22 (PubMed:17974559, PubMed:18187149)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W239", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0140595 MIM complex", "go_biological_process": "GO:0045040 protein insertion into mitochondrial outer membrane;GO:0015031 protein transport;GO:0070096 mitochondrial outer membrane translocase complex assembly", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q08176-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08182-1", "uniprot_id": "YAP7_YEAST", "mass": 27387.0, "length": 245, "protein_name": "AP-1-like transcription factor YAP7", "gene_name": "YAP7", "organism": "Yeast", "refseq_name": "Yap7p", "refseq_ac": "NP_014614", "gene_names_uniprotkb": "YAP7", "gene_names_refseq": "YAP7", "protein_names_uniprotkb": "AP-1-like transcription factor YAP7", "protein_names_refseq": "Yap7p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL028C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "12518319;14562095;14562106;17322287;21177495;23749301;24374639;30516470;33491328;9169874;9372930", "class_list": "", "function": "Probable transcription activator linked to cell cycle that induces transcription activation of genes in the environmental stress response and metabolism control pathways, like the closely related YAP5., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W237", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0000976 transcription cis-regulatory region binding;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q08182-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08199-1", "uniprot_id": "SIL1_YEAST", "mass": 48275.0, "length": 421, "protein_name": "Nucleotide exchange factor SIL1", "gene_name": "SIL1", "organism": "Yeast", "refseq_name": "Sil1p", "refseq_ac": "NP_014611", "gene_names_uniprotkb": "SIL1; PER100; SLS1", "gene_names_refseq": "SIL1; SLS1", "protein_names_uniprotkb": "Nucleotide exchange factor SIL1; Protein SLS1", "protein_names_refseq": "Sil1p", "tax_id": 559292, "disease": "Marinesco-Sjogren syndrome (Disease Ontology:DOID:0080195); primary cerebellar degeneration (Disease Ontology:DOID:9277)", "pathway": " (sce:YOL031C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10847680;10958688;11101517;14562106;14704430;17322287;19756047;21126336;24374639;33481703;33491328;9169874", "class_list": "", "function": "Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone KAR2., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 6, "predicted_n_glycosites": 6, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "D6W234;Q6B1H9", "ec_number_list": "", "go_molecular_function": "GO:0000774 adenyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005788 endoplasmic reticulum lumen", "go_biological_process": "GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q08199-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08202-1", "uniprot_id": "OPI10_YEAST", "mass": 27167.0, "length": 246, "protein_name": "Protein OPI10", "gene_name": "OPI10", "organism": "Yeast", "refseq_name": "Opi10p", "refseq_ac": "NP_014610", "gene_names_uniprotkb": "OPI10", "gene_names_refseq": "OPI10", "protein_names_uniprotkb": "Protein OPI10; Overproducer of inositol protein 10", "protein_names_refseq": "Opi10p", "tax_id": 559292, "disease": "hypomyelinating leukodystrophy 13 (Disease Ontology:DOID:0060795)", "pathway": " (sce:YOL032W); (R-SCE-3371453)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "14562095;14562106;16582425;18407956;24374639;33491328;9169874", "class_list": "", "function": "Involved in phospholipid biosynthesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W233", "ec_number_list": "", "go_molecular_function": "GO:0061608 nuclear import signal receptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006020 inositol metabolic process;GO:0008654 phospholipid biosynthetic process;GO:0006606 protein import into nucleus", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q08202-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08219-1", "uniprot_id": "RRT8_YEAST", "mass": 39600.0, "length": 342, "protein_name": "Outer spore wall protein RRT8", "gene_name": "RRT8", "organism": "Yeast", "refseq_name": "Rrt8p", "refseq_ac": "NP_014594", "gene_names_uniprotkb": "RRT8", "gene_names_refseq": "RRT8", "protein_names_uniprotkb": "Outer spore wall protein RRT8; Regulator of rDNA transcription protein 8", "protein_names_refseq": "Rrt8p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL048C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "12844361;14562095;16847258;19270272;23966878;24374639;9169874", "class_list": "", "function": "Involved in spore wall assembly (PubMed:23966878). May be involved in the modulation of rDNA transcription (PubMed:19270272)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W219;Q870H5", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005811 lipid droplet;GO:0005619 ascospore wall;GO:0005628 prospore membrane", "go_biological_process": "GO:0030476 ascospore wall assembly", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q08219-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08223-1", "uniprot_id": "AIM39_YEAST", "mass": 45851.0, "length": 395, "protein_name": "Altered inheritance of mitochondria protein 39, mitochondrial", "gene_name": "AIM39", "organism": "Yeast", "refseq_name": "Aim39p", "refseq_ac": "NP_014588", "gene_names_uniprotkb": "AIM39; O1269", "gene_names_refseq": "AIM39", "protein_names_uniprotkb": "Altered inheritance of mitochondria protein 39, mitochondrial", "protein_names_refseq": "Aim39p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL053W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "19300474;24374639;8789261;9169874", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W214;Q05667", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005777 peroxisome;GO:0005829 cytosol;GO:0031966 mitochondrial membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q08223-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08225-1", "uniprot_id": "DPP3_YEAST", "mass": 80510.0, "length": 711, "protein_name": "Probable dipeptidyl peptidase 3", "gene_name": "O1232", "organism": "Yeast", "refseq_name": "dipeptidyl-peptidase III", "refseq_ac": "NP_014584", "gene_names_uniprotkb": "O1232", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable dipeptidyl peptidase 3; 3.4.14.4; DPP III; Dipeptidyl aminopeptidase III; Dipeptidyl arylamidase III; Dipeptidyl peptidase III", "protein_names_refseq": "dipeptidyl-peptidase III", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL057W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562106;24374639;33491328;8789261;9169874", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O94146;Q05663", "ec_number_list": "", "go_molecular_function": "GO:0008239 dipeptidyl-peptidase activity;GO:0046872 metal ion binding;GO:0004177 aminopeptidase activity;GO:0008235 metalloexopeptidase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q08225-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08226-1", "uniprot_id": "CRT10_YEAST", "mass": 109715.0, "length": 957, "protein_name": "Protein CRT10", "gene_name": "CRT10", "organism": "Yeast", "refseq_name": "Crt10p", "refseq_ac": "NP_014578", "gene_names_uniprotkb": "CRT10", "gene_names_refseq": "CRT10", "protein_names_uniprotkb": "Protein CRT10; Constitutive RNR transcription regulator 10", "protein_names_refseq": "Crt10p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL063C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562106;16600900;17322287;18704118;19779198;24374639;33491328;9169874", "class_list": "", "function": "Substrate targeting component of a cullin-RING-based E3 ubiquitin-protein ligase complex RTT101(MMS1-CRT10). RTT101(MMS1-CRT10) may regulate nucleotide synthesis through transcriptional regulation of RNR genes encoding ribonucleotide reductases., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W204;Q6B2N4;Q7LGP7", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0070651 nonfunctional rRNA decay;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q08226-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08227-1", "uniprot_id": "INP54_YEAST", "mass": 43799.0, "length": 384, "protein_name": "Phosphatidylinositol 4,5-bisphosphate 5-phosphatase INP54", "gene_name": "INP54", "organism": "Yeast", "refseq_name": "phosphoinositide 5-phosphatase INP54", "refseq_ac": "NP_014576", "gene_names_uniprotkb": "INP54", "gene_names_refseq": "INP54", "protein_names_uniprotkb": "Phosphatidylinositol 4,5-bisphosphate 5-phosphatase INP54; 3.1.3.36", "protein_names_refseq": "phosphoinositide 5-phosphatase INP54", "tax_id": 559292, "disease": "muscular dystrophy-dystroglycanopathy type B1 (Disease Ontology:DOID:0050588); congenital muscular dystrophy with cataracts and intellectual disability (Disease Ontology:DOID:0080197)", "pathway": " (sce:YOL065C); (R-SCE-1660499); (R-SCE-1855183); (R-SCE-1855204)", "pathway_count": 4, "publication_count": 10, "publication_id_list": "10660045;11116155;14562106;18407956;21126336;23749301;24374639;33481703;33491328;9169874", "class_list": "", "function": "Regulates the phosphatidylinositol (4,5)-diphosphate levels on the cytoplasmic surface of the endoplasmic reticulum and thereby regulates secretion. Does not utilize phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2), nor phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 4-phosphate (PtdIns(4)P)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W202", "ec_number_list": "3.1.3.36;3.1.3.-", "go_molecular_function": "GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0015031 protein transport;GO:0046856 phosphatidylinositol dephosphorylation", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q08227-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08237-1", "uniprot_id": "REXO4_YEAST", "mass": 32895.0, "length": 289, "protein_name": "RNA exonuclease 4", "gene_name": "REX4", "organism": "Yeast", "refseq_name": "putative 3'-5' exonuclease", "refseq_ac": "NP_014561", "gene_names_uniprotkb": "REX4", "gene_names_refseq": "REX4", "protein_names_uniprotkb": "RNA exonuclease 4; 3.1.-.-", "protein_names_refseq": "putative 3'-5' exonuclease", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL080C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "12364601;14562095;14562106;15525710;24374639;33481703;33491328;9169874", "class_list": "", "function": "Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1Y8", "ec_number_list": "", "go_molecular_function": "GO:0003676 nucleic acid binding;GO:0008408 3'-5' exonuclease activity;GO:0004527 exonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus", "go_biological_process": "GO:0006396 RNA processing;GO:0006364 rRNA processing;GO:0000027 ribosomal large subunit assembly", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q08237-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08268-1", "uniprot_id": "MCH4_YEAST", "mass": 54707.0, "length": 501, "protein_name": "Probable transporter MCH4", "gene_name": "MCH4", "organism": "Yeast", "refseq_name": "Mch4p", "refseq_ac": "NP_014522", "gene_names_uniprotkb": "MCH4", "gene_names_refseq": "MCH4", "protein_names_uniprotkb": "Probable transporter MCH4", "protein_names_refseq": "Mch4p", "tax_id": 559292, "disease": "Allan-Herndon-Dudley syndrome (Disease Ontology:DOID:0050631); cataract 47 (Disease Ontology:DOID:0070353); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748)", "pathway": " (sce:YOL119C); (R-SCE-352230); (R-SCE-879518)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "11536335;16847258;22106047;23749301;24374639;32597660;33481703;33491328;34965436;8896268;9169874", "class_list": "", "function": "Probable transporter. Does not act in the transport of monocarboxylic acids across the plasma membrane., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W1U9", "ec_number_list": "", "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0015293 symporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0032218 riboflavin transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q08268-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08269-1", "uniprot_id": "ALR1_YEAST", "mass": 95869.0, "length": 859, "protein_name": "Magnesium transporter ALR1", "gene_name": "ALR1", "organism": "Yeast", "refseq_name": "Mg(2+) transporter ALR1", "refseq_ac": "NP_014511", "gene_names_uniprotkb": "ALR1", "gene_names_refseq": "ALR1; SWC3", "protein_names_uniprotkb": "Magnesium transporter ALR1; Aluminum resistance protein 1", "protein_names_refseq": "Mg(2+) transporter ALR1", "tax_id": 559292, "disease": "primary hypomagnesemia (Disease Ontology:DOID:0060879)", "pathway": " (sce:YOL130W)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "17322287;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;22814378;23749301;24374639;30516470;32597660;33481703;33491328;8896265;9169874;9430719", "class_list": "", "function": "Plasma membrane magnesium transporter., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 58, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1T8;Q02811", "ec_number_list": "", "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0015095 magnesium ion transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0015693 magnesium ion transport;GO:0006812 monoatomic cation transport;GO:0010961 intracellular magnesium ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "Q08269-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08271-1", "uniprot_id": "GAS4_YEAST", "mass": 53813.0, "length": 471, "protein_name": "1,3-beta-glucanosyltransferase GAS4", "gene_name": "GAS4", "organism": "Yeast", "refseq_name": "1,3-beta-glucanosyltransferase", "refseq_ac": "NP_014509", "gene_names_uniprotkb": "GAS4", "gene_names_refseq": "GAS4", "protein_names_uniprotkb": "1,3-beta-glucanosyltransferase GAS4; 2.4.1.-; Glycolipid-anchored surface protein 4", "protein_names_refseq": "1,3-beta-glucanosyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL132W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10383953;17189486;17397106;24374639;8896270;9169874", "class_list": "", "function": "Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall. Involved in spore wall assembly., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6W1T6", "ec_number_list": "", "go_molecular_function": "GO:0042124 1,3-beta-glucanosyltransferase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0000324 fungal-type vacuole;GO:0009277 fungal-type cell wall;GO:0098552 side of membrane", "go_biological_process": "GO:0030476 ascospore wall assembly;GO:0031505 fungal-type cell wall organization;GO:0071970 fungal-type cell wall (1->3)-beta-D-glucan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q08271-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08280-1", "uniprot_id": "BSC6_YEAST", "mass": 55084.0, "length": 497, "protein_name": "Bypass of stop codon protein 6", "gene_name": "BSC6", "organism": "Yeast", "refseq_name": "Bsc6p", "refseq_ac": "NP_014504", "gene_names_uniprotkb": "BSC6", "gene_names_refseq": "BSC6", "protein_names_uniprotkb": "Bypass of stop codon protein 6", "protein_names_refseq": "Bsc6p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL137W)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "12711673;14562095;14562106;16847258;17322287;17330950;17563356;18407956;19684113;19779198;20702584;23749301;24374639;32597660;33481703;33491328;8896270;9169874", "class_list": "", "function": "Probable transporter., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W1T2;Q6B229", "ec_number_list": "", "go_molecular_function": "GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0016020 membrane;GO:0030136 clathrin-coated vesicle;GO:0030137 COPI-coated vesicle", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "Q08280-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08295-1", "uniprot_id": "IMA2_YEAST", "mass": 68625.0, "length": 589, "protein_name": "Oligo-1,6-glucosidase IMA2", "gene_name": "IMA2", "organism": "Yeast", "refseq_name": "oligo-1,6-glucosidase IMA2", "refseq_ac": "NP_014485", "gene_names_uniprotkb": "IMA2", "gene_names_refseq": "IMA2", "protein_names_uniprotkb": "Oligo-1,6-glucosidase IMA2; 3.2.1.10; Alpha-glucosidase; Isomaltase 2", "protein_names_refseq": "oligo-1,6-glucosidase IMA2", "tax_id": 559292, "disease": "cystinuria (Disease Ontology:DOID:9266)", "pathway": " (sce:YOL157C); (R-SCE-352230)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "11389906;20562106;24374639;9169874", "class_list": "", "function": "Alpha-glucosidase with specificity for isomaltase, methyl-alpha-glucoside, and palatinose., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1R3", "ec_number_list": "3.2.1.10", "go_molecular_function": "GO:0004558 alpha-1,4-glucosidase activity;GO:0004556 alpha-amylase activity;GO:0004574 oligo-1,6-glucosidase activity;GO:0004575 sucrose alpha-glucosidase activity;GO:0033934 glucan 1,4-alpha-maltotriohydrolase activity", "go_cellular_component": "", "go_biological_process": "GO:0000025 maltose catabolic process;GO:0005987 sucrose catabolic process;GO:0046352 disaccharide catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q08295-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08299-1", "uniprot_id": "ENB1_YEAST", "mass": 66970.0, "length": 606, "protein_name": "Siderophore iron transporter ENB1", "gene_name": "ENB1", "organism": "Yeast", "refseq_name": "Enb1p", "refseq_ac": "NP_014484", "gene_names_uniprotkb": "ENB1; ARN4", "gene_names_refseq": "ARN4; ENB1", "protein_names_uniprotkb": "Siderophore iron transporter ENB1; Enterobactin permease; Siderophore iron transporter ARN4", "protein_names_refseq": "Enb1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL158C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10744769;12196168;16847258;17287358;19779198;21177495;24374639;32597660;33481703;33491328;34965436;9169874", "class_list": "", "function": "Involved in the transport of siderophore enterobactin and so has a role in iron homeostasis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1R2", "ec_number_list": "", "go_molecular_function": "GO:0015343 siderophore-iron transmembrane transporter activity;GO:0015620 ferric-enterobactin transmembrane transporter activity", "go_cellular_component": "GO:0005768 endosome;GO:0005886 plasma membrane;GO:0010008 endosome membrane;GO:0071944 cell periphery;GO:0005774 vacuolar membrane", "go_biological_process": "GO:0055085 transmembrane transport;GO:0006879 intracellular iron ion homeostasis;GO:0015685 ferric-enterobactin import into cell", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q08299-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08347-1", "uniprot_id": "BDS1_YEAST", "mass": 72646.0, "length": 646, "protein_name": "Alkyl/aryl-sulfatase BDS1", "gene_name": "BDS1", "organism": "Yeast", "refseq_name": "sulfuric ester hydrolase", "refseq_ac": "NP_014478", "gene_names_uniprotkb": "BDS1", "gene_names_refseq": "BDS1", "protein_names_uniprotkb": "Alkyl/aryl-sulfatase BDS1; 3.1.6.-; Bacterially-derived sulfatase 1", "protein_names_refseq": "sulfuric ester hydrolase", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL164W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "12414795;15947202;22814378;24374639;33491328;9169874", "class_list": "", "function": "Alkyl/aryl-sulfatase. Enables the use of SDS and 4-nitrocatechol as sulfur source., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1Q6", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0046983 protein dimerization activity;GO:0018741 linear primary-alkylsulfatase activity", "go_cellular_component": "", "go_biological_process": "GO:0018909 dodecyl sulfate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q08347-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08409-1", "uniprot_id": "AUS1_YEAST", "mass": 157751.0, "length": 1394, "protein_name": "ATP-dependent permease AUS1", "gene_name": "AUS1", "organism": "Yeast", "refseq_name": "ATP-binding cassette sterol transporter AUS1", "refseq_ac": "NP_014654", "gene_names_uniprotkb": "AUS1", "gene_names_refseq": "AUS1", "protein_names_uniprotkb": "ATP-dependent permease AUS1", "protein_names_refseq": "ATP-binding cassette sterol transporter AUS1", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR011W)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12077145;24374639;9169874", "class_list": "", "function": "Transporter involved in the uptake of sterol., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W278;O94147", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0034041 ABC-type sterol transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005886 plasma membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0035376 sterol import", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q08409-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08416-1", "uniprot_id": "IRC23_YEAST", "mass": 18092.0, "length": 157, "protein_name": "Increased recombination centers protein 23", "gene_name": "IRC23", "organism": "Yeast", "refseq_name": "Irc23p", "refseq_ac": "NP_014687", "gene_names_uniprotkb": "IRC23", "gene_names_refseq": "IRC23", "protein_names_uniprotkb": "Increased recombination centers protein 23", "protein_names_refseq": "Irc23p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR044W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562095;14562106;16847258;16943074;17322287;18085829;19779198;24374639;33491328;9169874", "class_list": "", "function": "Is probably involved in a pathway contributing to genomic integrity., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2B0", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q08416-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08421-1", "uniprot_id": "ETT1_YEAST", "mass": 47352.0, "length": 412, "protein_name": "Enhancer of translation termination 1", "gene_name": "ETT1", "organism": "Yeast", "refseq_name": "Ett1p", "refseq_ac": "NP_014694", "gene_names_uniprotkb": "ETT1; YOR29-02", "gene_names_refseq": "ETT1; NRO1; YOR29-02", "protein_names_uniprotkb": "Enhancer of translation termination 1", "protein_names_refseq": "Ett1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR051C)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "10684247;14562095;14562106;14671320;15044472;17322287;17563356;18407956;19684113;19779198;20630870;20702584;21126336;21177495;23749301;24374639;28270554;32597660;33481703;33491328;9133743;9169874", "class_list": "", "function": "Required for correct translation termination and probably involved in regulation of hypoxic gene expression in association TPA1. Inhibits replication of Brome mosaic virus., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2B6;O00016;Q6Q5I2", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006415 translational termination;GO:0006417 regulation of translation;GO:2000640 positive regulation of SREBP signaling pathway", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "Q08421-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08422-1", "uniprot_id": "TMC1_YEAST", "mass": 16734.0, "length": 150, "protein_name": "AN1-type zinc finger protein TMC1", "gene_name": "TMC1", "organism": "Yeast", "refseq_name": "Tmc1p", "refseq_ac": "NP_014695", "gene_names_uniprotkb": "TMC1; YOR29-03", "gene_names_refseq": "TMC1; YOR29-03", "protein_names_uniprotkb": "AN1-type zinc finger protein TMC1; Trivalent metalloid-sensitive Cuz1-related protein 1", "protein_names_refseq": "Tmc1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR052C)", "pathway_count": 1, "publication_count": 25, "publication_id_list": "11875433;14562095;14562106;15665377;17322287;17330950;17563356;18407956;19779198;19795423;19823750;21126336;21177495;22218487;22814378;23749301;24297164;24374639;24909858;30516470;32597660;33481703;33491328;9133743;9169874", "class_list": "", "function": "May have a role in protecting cells from metalloid-induced proteotoxicity., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2B7;O00017", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0071218 cellular response to misfolded protein;GO:0071243 cellular response to arsenic-containing substance", "synthesized_glycan_count": 0, "hit_score": 2.6, "record_id": "Q08422-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08471-1", "uniprot_id": "MSA1_YEAST", "mass": 68691.0, "length": 629, "protein_name": "G1-specific transcription factors activator MSA1", "gene_name": "MSA1", "organism": "Yeast", "refseq_name": "Msa1p", "refseq_ac": "NP_014709", "gene_names_uniprotkb": "MSA1; YOR29-17", "gene_names_refseq": "MSA1; YOR29-17", "protein_names_uniprotkb": "G1-specific transcription factors activator MSA1; MBF and SBF-associated protein 1", "protein_names_refseq": "Msa1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR066W)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "14574415;16464826;17322287;18160399;18407956;19520826;19684113;19779198;21126336;23749301;24374639;25733686;32597660;33481703;33491328;9133743;9169874", "class_list": "", "function": "Activator of G1-specific transcription factors, MBF and SBF. Promotes both the timing of G1-specific gene transcription and cell cycle initiation. Associates with SBF- and MBF-regulated target promoters and this binding is maximal during the G1 phase, prior to maximum budding. Affects cell cycle initiation by advancing the timing of transcription of G1-specific genes. Overexpression advances the timing of SBF-dependent transcription and budding. Depletion delays both indicators of cell cycle initiation., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 26, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2C9;O00026", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0000082 G1/S transition of mitotic cell cycle;GO:0007089 traversing start control point of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q08471-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08485-1", "uniprot_id": "NRT1_YEAST", "mass": 67193.0, "length": 598, "protein_name": "Nicotinamide riboside transporter 1", "gene_name": "NRT1", "organism": "Yeast", "refseq_name": "nicotinamide riboside transporter", "refseq_ac": "NP_014714", "gene_names_uniprotkb": "NRT1; THI71; YOR29-22", "gene_names_refseq": "NRT1; THI71; YOR29-22", "protein_names_uniprotkb": "Nicotinamide riboside transporter 1; Thiamine transport protein 71", "protein_names_refseq": "nicotinamide riboside transporter", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR071C)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "16845689;16850348;18258590;18407956;19416965;19779198;21349851;24374639;32597660;33481703;33491328;9133743;9169874;9235906", "class_list": "", "function": "High-affinity pH-dependent nicotinamide riboside transporter which also transports thiamine with low affinity. Involved in 5-fluorocytosine sensitivity., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2D4;O00029", "ec_number_list": "", "go_molecular_function": "GO:0015205 nucleobase transmembrane transporter activity;GO:0034257 nicotinamide riboside transmembrane transporter activity;GO:1903089 5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0015851 nucleobase transport;GO:0015888 thiamine transport;GO:0034258 nicotinamide riboside transport;GO:1903088 5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q08485-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08553-1", "uniprot_id": "SYC1_YEAST", "mass": 20866.0, "length": 188, "protein_name": "Protein SYC1", "gene_name": "SYC1", "organism": "Yeast", "refseq_name": "cleavage polyadenylation factor subunit SYC1", "refseq_ac": "NP_014822", "gene_names_uniprotkb": "SYC1", "gene_names_refseq": "SYC1", "protein_names_uniprotkb": "Protein SYC1", "protein_names_refseq": "cleavage polyadenylation factor subunit SYC1", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR179C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "12819204;14562095;14562106;22814378;24374639;9169874", "class_list": "", "function": "Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. Component of the APT complex, which may be involved in polyadenylation-independent transcript 3'-end formation, including snoRNAs and snRNAs., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2N5", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005847 mRNA cleavage and polyadenylation specificity factor complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0031441 negative regulation of mRNA 3'-end processing;GO:0030846 termination of RNA polymerase II transcription, poly(A)-coupled", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q08553-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08561-1", "uniprot_id": "IES4_YEAST", "mass": 13092.0, "length": 116, "protein_name": "Ino eighty subunit 4", "gene_name": "IES4", "organism": "Yeast", "refseq_name": "Ies4p", "refseq_ac": "NP_014832", "gene_names_uniprotkb": "IES4", "gene_names_refseq": "IES4", "protein_names_uniprotkb": "Ino eighty subunit 4", "protein_names_refseq": "Ies4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR189W)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "12887900;14562095;14562106;17693258;18407956;19795423;19823750;20190278;21126336;21177495;22218487;23749301;24374639;32597660;33481703;33491328;9169874", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 19, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2P5", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0031011 Ino80 complex", "go_biological_process": "GO:0006281 DNA repair;GO:0006338 chromatin remodeling;GO:0006355 regulation of DNA-templated transcription;GO:0006974 DNA damage response;GO:0000722 telomere maintenance via recombination", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q08561-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08579-1", "uniprot_id": "THI72_YEAST", "mass": 67186.0, "length": 599, "protein_name": "Thiamine transporter THI72", "gene_name": "THI72", "organism": "Yeast", "refseq_name": "thiamine transporter", "refseq_ac": "NP_014835", "gene_names_uniprotkb": "THI72", "gene_names_refseq": "THI72", "protein_names_uniprotkb": "Thiamine transporter THI72", "protein_names_refseq": "thiamine transporter", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR192C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "16194233;24374639;9169874;9235906", "class_list": "", "function": "Low affinity thiamine transporter responsible for intake of thiamine. It is possible that the primary function is the uptake of closely related compounds and that thiamine transport is a secondary activity of these proteins., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2P8", "ec_number_list": "", "go_molecular_function": "GO:0015205 nucleobase transmembrane transporter activity;GO:1903089 5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0015851 nucleobase transport;GO:0015888 thiamine transport;GO:1903088 5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q08579-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08580-1", "uniprot_id": "PEX27_YEAST", "mass": 44131.0, "length": 376, "protein_name": "Peroxisomal membrane protein PEX27", "gene_name": "PEX27", "organism": "Yeast", "refseq_name": "Pex27p", "refseq_ac": "NP_014836", "gene_names_uniprotkb": "PEX27", "gene_names_refseq": "PEX27", "protein_names_uniprotkb": "Peroxisomal membrane protein PEX27; Peroxin-27", "protein_names_refseq": "Pex27p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR193W)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "14517321;14517338;14562095;14562106;17322287;19684113;19779198;21441307;24374639;32597660;33481703;33491328;9169874", "class_list": "", "function": "Required for regulation of peroxisome size and number. Also promotes peroxisome division and biogenesis., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2Q2", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005777 peroxisome;GO:0005778 peroxisomal membrane", "go_biological_process": "GO:0016559 peroxisome fission;GO:0007031 peroxisome organization;GO:0044375 regulation of peroxisome size", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q08580-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08622-1", "uniprot_id": "GEP3_YEAST", "mass": 63853.0, "length": 556, "protein_name": "Genetic interactor of prohibitins 3, mitochondrial", "gene_name": "GEP3", "organism": "Yeast", "refseq_name": "Gep3p", "refseq_ac": "NP_014848", "gene_names_uniprotkb": "GEP3; AIM40; FMP48", "gene_names_refseq": "AIM40; FMP38; GEP3; MTG3", "protein_names_uniprotkb": "Genetic interactor of prohibitins 3, mitochondrial; Altered inheritance of mitochondria protein 40; Found in mitochondrial proteome protein 38", "protein_names_refseq": "Gep3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR205C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562095;14562106;14576278;19300474;19751518;24374639;9169874", "class_list": "", "function": "Interacts genetically with prohibitins and thus may be involved in the mitochondrial lipid metabolism., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2R1", "ec_number_list": "", "go_molecular_function": "GO:0005525 GTP binding;GO:0097177 mitochondrial ribosome binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0030490 maturation of SSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q08622-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08646-1", "uniprot_id": "SSP2_YEAST", "mass": 43100.0, "length": 371, "protein_name": "Sporulation-specific protein 2", "gene_name": "SSP2", "organism": "Yeast", "refseq_name": "Ssp2p", "refseq_ac": "NP_014885", "gene_names_uniprotkb": "SSP2; O5251", "gene_names_refseq": "SSP2", "protein_names_uniprotkb": "Sporulation-specific protein 2", "protein_names_refseq": "Ssp2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR242C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "12073037;14562106;24374639;33491328;8972580;9169874", "class_list": "", "function": "Essential for sporulation and seems to have a role at the time of, or after, initiation of nuclear division. Appears to have a role in outer spore wall formation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2U4;Q96US5", "ec_number_list": "", "go_molecular_function": "GO:0030295 protein kinase activator activity;GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005619 ascospore wall;GO:0005628 prospore membrane", "go_biological_process": "GO:0031954 positive regulation of protein autophosphorylation;GO:0030437 ascospore formation;GO:0030476 ascospore wall assembly", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q08646-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08673-1", "uniprot_id": "SRL1_YEAST", "mass": 22048.0, "length": 210, "protein_name": "Cell wall protein SRL1", "gene_name": "SRL1", "organism": "Yeast", "refseq_name": "Srl1p", "refseq_ac": "NP_014890", "gene_names_uniprotkb": "SRL1", "gene_names_refseq": "SRL1", "protein_names_uniprotkb": "Cell wall protein SRL1", "protein_names_refseq": "Srl1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR247W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "11935221;13679573;14562095;15165243;15972461;24374639;9153759;9169874", "class_list": "", "function": "Required to stabilize the cell wall in the absence of multiple GPI-anchored mannoproteins., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "D6W2U9", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0009986 cell surface;GO:0071944 cell periphery;GO:0000324 fungal-type vacuole;GO:0005934 cellular bud tip", "go_biological_process": "GO:0006139 nucleobase-containing compound metabolic process;GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q08673-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08686-1", "uniprot_id": "THTR_YEAST", "mass": 34219.0, "length": 304, "protein_name": "Sulfurtransferase TUM1", "gene_name": "TUM1", "organism": "Yeast", "refseq_name": "thiosulfate sulfurtransferase", "refseq_ac": "NP_014894", "gene_names_uniprotkb": "TUM1", "gene_names_refseq": "TUM1", "protein_names_uniprotkb": "Sulfurtransferase TUM1; 2.8.1.2; Thiouridine modification protein 1; tRNA-thiouridine modification protein 1", "protein_names_refseq": "thiosulfate sulfurtransferase", "tax_id": 559292, "disease": "type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (sce:YOR251C); (R-SCE-1614558)", "pathway_count": 2, "publication_count": 18, "publication_id_list": "14562095;14562106;17322287;18407956;18755837;19151091;19779198;22587783;22684328;24374639;27915245;28357324;28830344;31240288;33491328;39673271;9153759;9169874", "class_list": "", "function": "Sulfur transferase that accepts persulfite from NFS1 and transfers it to UBA4 in the pathway for 2-thiolation of the wobble uridine base of tRNAs (PubMed:18755837, PubMed:19151091, PubMed:28357324). Stimulates sulfur transfer by NFS1 (PubMed:19151091). S-transfer via TUM1 is also critical for proper AHP1 urmylation (PubMed:28357324). TUM1 appears to be able to substitute for the rhodanese (RHD) domain of UBA4 and deliver sulfur directly to the C-terminus of UBA4-bound URM1 (PubMed:39673271). Partly responsible for the early production of H(2)S from cysteine via a novel pathway that does not convert cysteine to sulfate or sulfite, but rather to sulfide (PubMed:27915245). Regulates the production of cysteine- and glutathione-persulfide (Cys-SSH and GSSH) (PubMed:31240288). Finally, plays a role in metabolism of sterol esters in a tRNA thiolation pathway-independent manner (PubMed:28830344)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2V2", "ec_number_list": "2.8.1.2", "go_molecular_function": "GO:0016784 3-mercaptopyruvate sulfurtransferase activity;GO:0004792 thiosulfate-cyanide sulfurtransferase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0002143 tRNA wobble position uridine thiolation;GO:0002098 tRNA wobble uridine modification", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "Q08686-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08693-1", "uniprot_id": "TRE2_YEAST", "mass": 91995.0, "length": 809, "protein_name": "Putative zinc metalloprotease TRE2", "gene_name": "TRE2", "organism": "Yeast", "refseq_name": "putative zinc metalloprotease", "refseq_ac": "NP_014899", "gene_names_uniprotkb": "TRE2", "gene_names_refseq": "TRE2", "protein_names_uniprotkb": "Putative zinc metalloprotease TRE2; 3.-.-.-; Transferrin receptor-like protein 2", "protein_names_refseq": "putative zinc metalloprotease", "tax_id": 559292, "disease": "hemochromatosis type 3 (Disease Ontology:DOID:0111030); immunodeficiency 46 (Disease Ontology:DOID:0111948); prostate cancer (Disease Ontology:DOID:10283); iron deficiency anemia (Disease Ontology:DOID:11758); breast cancer (Disease Ontology:DOID:1612); hemochromatosis (Disease Ontology:DOID:2352); ovarian cancer (Disease Ontology:DOID:2394); transitional cell carcinoma (Disease Ontology:DOID:2671); breast carcinoma (Disease Ontology:DOID:3459); cerebral infarction (Disease Ontology:DOID:3526); cervical adenocarcinoma (Disease Ontology:DOID:3702); Weissenbacher-Zweymuller syndrome (Disease Ontology:DOID:4258); renal cell carcinoma (Disease Ontology:DOID:4450); abdominal aortic aneurysm (Disease Ontology:DOID:7693); acute myeloid leukemia (Disease Ontology:DOID:9119); multiple myeloma (Disease Ontology:DOID:9538)", "pathway": " (sce:YOR256C); (R-SCE-8963693)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "14562095;14562106;24374639;32597660;33491328;9153759;9169874", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 16, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6W2V7", "ec_number_list": "3.4.-.-;3.-.-.-", "go_molecular_function": "GO:0008237 metallopeptidase activity;GO:0046872 metal ion binding;GO:0004180 carboxypeptidase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q08693-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08729-1", "uniprot_id": "DSE3_YEAST", "mass": 48099.0, "length": 430, "protein_name": "Protein DSE3", "gene_name": "DSE3", "organism": "Yeast", "refseq_name": "Dse3p", "refseq_ac": "NP_014907", "gene_names_uniprotkb": "DSE3", "gene_names_refseq": "DSE3", "protein_names_uniprotkb": "Protein DSE3; Daughter specific expression protein 3", "protein_names_refseq": "Dse3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR264W)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "11309124;11747810;14562095;14562106;16278933;17322287;19779198;19795423;19823750;21177495;23749301;24374639;32597660;33481703;33491328;9153759;9169874", "class_list": "", "function": "May be involved in the establishment of the daughter fate., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2W4", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005935 cellular bud neck", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q08729-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08732-1", "uniprot_id": "HRK1_YEAST", "mass": 85696.0, "length": 759, "protein_name": "Serine/threonine-protein kinase HRK1", "gene_name": "HRK1", "organism": "Yeast", "refseq_name": "putative serine/threonine protein kinase HRK1", "refseq_ac": "NP_014910", "gene_names_uniprotkb": "HRK1", "gene_names_refseq": "HRK1", "protein_names_uniprotkb": "Serine/threonine-protein kinase HRK1; 2.7.11.1; Hygromycin resistance kinase 1", "protein_names_refseq": "putative serine/threonine protein kinase HRK1", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR267C); (R-SCE-176187); (R-SCE-5693616); (R-SCE-69601)", "pathway_count": 4, "publication_count": 26, "publication_id_list": "11003661;14562095;14562106;15665377;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20489023;20702584;21126336;21177495;22218487;23749301;24374639;32597660;33229814;33481703;33491328;8896271;9153759;9169874", "class_list": "", "function": "Involved in regulating the activity of the plasma membrane proton pump PMA1., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 53, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6W2W7;Q07224", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;3.1.3.48;2.7.11.13;3.6.4.-;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006873 intracellular monoatomic ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 3.1, "record_id": "Q08732-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08742-1", "uniprot_id": "RDL2_YEAST", "mass": 16697.0, "length": 149, "protein_name": "Thiosulfate sulfurtransferase RDL2, mitochondrial", "gene_name": "RDL2", "organism": "Yeast", "refseq_name": "thiosulfate sulfurtransferase RDL2", "refseq_ac": "NP_014929", "gene_names_uniprotkb": "RDL2; AIM42; FMP31", "gene_names_refseq": "AIM42; RDL2", "protein_names_uniprotkb": "Thiosulfate sulfurtransferase RDL2, mitochondrial; 2.8.1.1; Altered inheritance of mitochondria protein 42; Found in mitochondrial proteome protein 31; Rhodanese-like protein 2", "protein_names_refseq": "thiosulfate sulfurtransferase RDL2", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR286W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562095;14562106;14576278;17322287;19300474;19864628;24374639;33491328;9169874", "class_list": "", "function": "Thiosulfate sulfurtransferase which catalyzes the transfer of sulfane sulfur from thiosulfate to cyanide., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2Y4", "ec_number_list": "2.8.1.1", "go_molecular_function": "GO:0004792 thiosulfate-cyanide sulfurtransferase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006790 sulfur compound metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q08742-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08745-1", "uniprot_id": "RS10A_YEAST", "mass": 12739.0, "length": 105, "protein_name": "Small ribosomal subunit protein eS10A", "gene_name": "RPS10A", "organism": "Yeast", "refseq_name": "40S ribosomal protein eS10 RPS10A", "refseq_ac": "NP_014936", "gene_names_uniprotkb": "RPS10A", "gene_names_refseq": "RPS10A", "protein_names_uniprotkb": "Small ribosomal subunit protein eS10A; 40S ribosomal protein S10-A", "protein_names_refseq": "40S ribosomal protein eS10 RPS10A", "tax_id": 559292, "disease": "Diamond-Blackfan anemia 9 (Disease Ontology:DOID:0111884)", "pathway": " (sce:YOR293W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10601260;14562106;15665377;22096102;22814378;24374639;24524803;25437641;32597660;9153758;9169874;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (PubMed:22096102). eS10 plays a role as a positive regulator of the GCN2 kinase activity by stimulating GCN1-mediated GCN2 activation (PubMed:25437641)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2Z1", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005829 cytosol;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0045860 positive regulation of protein kinase activity;GO:0000054 ribosomal subunit export from nucleus;GO:0034198 cellular response to amino acid starvation;GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q08745-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08750-1", "uniprot_id": "MUM3_YEAST", "mass": 57237.0, "length": 479, "protein_name": "Protein MUM3", "gene_name": "MUM3", "organism": "Yeast", "refseq_name": "Mum3p", "refseq_ac": "NP_014941", "gene_names_uniprotkb": "MUM3", "gene_names_refseq": "MUM3", "protein_names_uniprotkb": "Protein MUM3; Muddled meiosis protein 3", "protein_names_refseq": "Mum3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR298W); (R-SCE-1482925); (R-SCE-1483166)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "12432101;15590821;24374639;9153758;9169874;9504908", "class_list": "", "function": "Involved in the organization of the outer spore wall layers and especially in the assembly of the chitosan layer., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W2Z7", "ec_number_list": "", "go_molecular_function": "GO:0016746 acyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0008654 phospholipid biosynthetic process;GO:0036149 phosphatidylinositol acyl-chain remodeling;GO:0030476 ascospore wall assembly", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q08750-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08777-1", "uniprot_id": "MCH5_YEAST", "mass": 57582.0, "length": 521, "protein_name": "Riboflavin transporter MCH5", "gene_name": "MCH5", "organism": "Yeast", "refseq_name": "riboflavin transporter", "refseq_ac": "NP_014951", "gene_names_uniprotkb": "MCH5", "gene_names_refseq": "MCH5", "protein_names_uniprotkb": "Riboflavin transporter MCH5", "protein_names_refseq": "riboflavin transporter", "tax_id": 559292, "disease": "Allan-Herndon-Dudley syndrome (Disease Ontology:DOID:0050631); cataract 47 (Disease Ontology:DOID:0070353)", "pathway": " (sce:YOR306C); (R-SCE-352230); (R-SCE-879518)", "pathway_count": 3, "publication_count": 7, "publication_id_list": "11536335;16204239;16847258;24374639;33481703;9153758;9169874", "class_list": "", "function": "Riboflavin transporter involved in riboflavin (vitamin B2) uptake. Does not act in the transport of monocarboxylic acids across the plasma membrane., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6W306", "ec_number_list": "", "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0032217 riboflavin transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0032218 riboflavin transport", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q08777-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08818-1", "uniprot_id": "MSC6_YEAST", "mass": 79947.0, "length": 692, "protein_name": "Meiotic sister-chromatid recombination protein 6, mitochondrial", "gene_name": "MSC6", "organism": "Yeast", "refseq_name": "Msc6p", "refseq_ac": "NP_014999", "gene_names_uniprotkb": "MSC6", "gene_names_refseq": "MSC6", "protein_names_uniprotkb": "Meiotic sister-chromatid recombination protein 6, mitochondrial", "protein_names_refseq": "Msc6p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR354C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10511544;14562095;14562106;14576278;24374639;33491328;9169874", "class_list": "", "function": "May be involved in the control of meiotic sister-chromatid recombination., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W349", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0070124 mitochondrial translational initiation;GO:0007131 reciprocal meiotic recombination", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q08818-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08822-1", "uniprot_id": "ETFD_YEAST", "mass": 69634.0, "length": 631, "protein_name": "Probable electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "gene_name": "CIR2", "organism": "Yeast", "refseq_name": "electron-transferring-flavoprotein dehydrogenase", "refseq_ac": "NP_015001", "gene_names_uniprotkb": "CIR2", "gene_names_refseq": "CIR2", "protein_names_uniprotkb": "Probable electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial; 1.5.5.1; Changed intracellular redox state protein 2; ETF dehydrogenase; ETF-QO; ETF-ubiquinone oxidoreductase; Electron-transferring-flavoprotein dehydrogenase", "protein_names_refseq": "electron-transferring-flavoprotein dehydrogenase", "tax_id": 559292, "disease": "multiple acyl-CoA dehydrogenase deficiency (Disease Ontology:DOID:0060358)", "pathway": " (sce:YOR356W); (R-SCE-611105)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "11502169;14562095;14562106;14576278;21253464;23749301;24374639;9169874", "class_list": "", "function": "Links fatty acid beta-oxidation and amino acid catabolism to the respiratory chain by transferring electrons from the electron transfer flavoprotein (ETF) to ubiquinone., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W351", "ec_number_list": "1.5.5.1", "go_molecular_function": "GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0004174 electron-transferring-flavoprotein dehydrogenase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0022900 electron transport chain", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q08822-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08902-1", "uniprot_id": "AMF1_YEAST", "mass": 56110.0, "length": 515, "protein_name": "Low affinity ammonium transporter", "gene_name": "AMF1", "organism": "Yeast", "refseq_name": "Amf1p", "refseq_ac": "NP_015023", "gene_names_uniprotkb": "AMF1", "gene_names_refseq": "AMF1", "protein_names_uniprotkb": "Low affinity ammonium transporter; Ammonium facilitator 1", "protein_names_refseq": "Amf1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR378W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "11562456;16278933;16630275;16847258;19414602;24374639;24707045;9169874", "class_list": "", "function": "Low affinity ammonium transporter of the plasma membrane (PubMed:24707045). May be involved in drug resistance through pumping them out of the cell (By similarity)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W371", "ec_number_list": "", "go_molecular_function": "GO:0008519 ammonium channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0072488 ammonium transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q08902-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08904-1", "uniprot_id": "RDR1_YEAST", "mass": 61287.0, "length": 546, "protein_name": "Protein RDR1", "gene_name": "RDR1", "organism": "Yeast", "refseq_name": "Rdr1p", "refseq_ac": "NP_015025", "gene_names_uniprotkb": "RDR1", "gene_names_refseq": "RDR1", "protein_names_uniprotkb": "Protein RDR1; Repressor of drug resistance protein 1", "protein_names_refseq": "Rdr1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR380W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "11353088;11882665;24374639;32597660;33481703;33491328;9169874", "class_list": "", "function": "Transcriptional repressor of multidrug resistance genes, such as PDR5. Required for growth on non-fermentable carbon sources like lactate or glycerol., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W372", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0009410 response to xenobiotic stimulus", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q08904-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08906-1", "uniprot_id": "FIT2_YEAST", "mass": 15302.0, "length": 153, "protein_name": "Facilitator of iron transport 2", "gene_name": "FIT2", "organism": "Yeast", "refseq_name": "Fit2p", "refseq_ac": "NP_015027", "gene_names_uniprotkb": "FIT2", "gene_names_refseq": "FIT2", "protein_names_uniprotkb": "Facilitator of iron transport 2", "protein_names_refseq": "Fit2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR382W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10383953;11673473;18407956;24374639;33491328;9169874", "class_list": "", "function": "Involved in the uptake of non-siderophore and siderophore sources of iron. Has a role in the retention of iron in the cell wall and periplasmic space., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W375", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0071944 cell periphery;GO:0000324 fungal-type vacuole;GO:0009277 fungal-type cell wall;GO:0098552 side of membrane", "go_biological_process": "GO:0015891 siderophore transport", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q08906-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08907-1", "uniprot_id": "FIT3_YEAST", "mass": 19836.0, "length": 204, "protein_name": "Facilitator of iron transport 3", "gene_name": "FIT3", "organism": "Yeast", "refseq_name": "Fit3p", "refseq_ac": "NP_015028", "gene_names_uniprotkb": "FIT3", "gene_names_refseq": "FIT3", "protein_names_uniprotkb": "Facilitator of iron transport 3", "protein_names_refseq": "Fit3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR383C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10383953;11673473;24374639;9169874", "class_list": "", "function": "Involved in the uptake of non-siderophore and siderophore sources of iron. Has a role in the retention of iron in the cell wall and periplasmic space., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W376", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0071944 cell periphery;GO:0000324 fungal-type vacuole;GO:0009277 fungal-type cell wall;GO:0098552 side of membrane", "go_biological_process": "GO:0015891 siderophore transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q08907-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08908-1", "uniprot_id": "FRE5_YEAST", "mass": 80292.0, "length": 694, "protein_name": "Ferric reductase transmembrane component 5", "gene_name": "FRE5", "organism": "Yeast", "refseq_name": "putative ferric-chelate reductase", "refseq_ac": "NP_015029", "gene_names_uniprotkb": "FRE5; O6765", "gene_names_refseq": "FRE5", "protein_names_uniprotkb": "Ferric reductase transmembrane component 5; 1.16.1.9; Ferric-chelate reductase 5", "protein_names_refseq": "putative ferric-chelate reductase", "tax_id": 559292, "disease": "congenital hypothyroidism (Disease Ontology:DOID:0050328); primary bacterial infectious disease (Disease Ontology:DOID:0050338); renal fibrosis (Disease Ontology:DOID:0050855); X-linked chronic granulomatous disease (Disease Ontology:DOID:0070195); metabolic dysfunction-associated steatohepatitis (Disease Ontology:DOID:0080547); immunodeficiency 34 (Disease Ontology:DOID:0112000); thyroid dyshormonogenesis 6 (Disease Ontology:DOID:0112189); hypertension (Disease Ontology:DOID:10763); cholera (Disease Ontology:DOID:1498); chronic granulomatous disease (Disease Ontology:DOID:3265); primary hyperaldosteronism (Disease Ontology:DOID:446); myocardial infarction (Disease Ontology:DOID:5844); pulmonary hypertension (Disease Ontology:DOID:6432); end stage renal disease (Disease Ontology:DOID:783); ulcerative colitis (Disease Ontology:DOID:8577); Crohn's disease (Disease Ontology:DOID:8778); steatotic liver disease (Disease Ontology:DOID:9452); obesity (Disease Ontology:DOID:9970)", "pathway": " (sce:YOR384W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10341420;17322287;24374639;9169874;9726978", "class_list": "", "function": "Metalloreductase responsible for reducing extracellular iron and copper prior to import. Catalyzes the reductive uptake of Fe(3+)-salts and Fe(3+) bound to catecholate or hydroxamate siderophores. Fe(3+) is reduced to Fe(2+), which then dissociates from the siderophore and can be imported by the high-affinity Fe(2+) transport complex in the plasma membrane (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 18, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W377", "ec_number_list": "1.16.1.9", "go_molecular_function": "GO:0046872 metal ion binding;GO:0052851 ferric-chelate reductase (NADPH) activity;GO:0000293 ferric-chelate reductase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005886 plasma membrane", "go_biological_process": "GO:0006879 intracellular iron ion homeostasis;GO:0015677 copper ion import;GO:0006826 iron ion transport", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q08908-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08911-1", "uniprot_id": "FDH1_YEAST", "mass": 41714.0, "length": 376, "protein_name": "Formate dehydrogenase 1", "gene_name": "FDH1", "organism": "Yeast", "refseq_name": "formate dehydrogenase (NAD+)", "refseq_ac": "NP_015033", "gene_names_uniprotkb": "FDH1", "gene_names_refseq": "FDH1", "protein_names_uniprotkb": "Formate dehydrogenase 1; 1.17.1.9; FDH; NAD-dependent formate dehydrogenase", "protein_names_refseq": "formate dehydrogenase (NAD+)", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR388C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "11921099;12144528;24374639;9169874;9178506", "class_list": "", "function": "Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms (PubMed:11921099, PubMed:12144528, PubMed:9178506). Has a role in the detoxification of exogenous formate in non-methylotrophic organisms (PubMed:11921099)., [UniProtKB, HAMAP, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W381", "ec_number_list": "1.17.1.9", "go_molecular_function": "GO:0051287 NAD binding;GO:0008863 formate dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0042183 formate catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q08911-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08913-1", "uniprot_id": "FEX1_YEAST", "mass": 41985.0, "length": 375, "protein_name": "Fluoride export protein 1", "gene_name": "FEX1", "organism": "Yeast", "refseq_name": "fluoride transporter", "refseq_ac": "NP_015035", "gene_names_uniprotkb": "FEX1", "gene_names_refseq": "FEX1", "protein_names_uniprotkb": "Fluoride export protein 1", "protein_names_refseq": "fluoride transporter", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR390W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "24173035;24374639;26055717;9169874", "class_list": "", "function": "Fluoride channel required for the rapid expulsion of cytoplasmic fluoride., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6W383", "ec_number_list": "", "go_molecular_function": "GO:1903425 fluoride transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery", "go_biological_process": "GO:1903424 fluoride transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q08913-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08914-1", "uniprot_id": "HSP33_YEAST", "mass": 25926.0, "length": 237, "protein_name": "Probable glutathione-independent glyoxalase HSP33", "gene_name": "HSP33", "organism": "Yeast", "refseq_name": "glutathione-independent methylglyoxalase family protein", "refseq_ac": "NP_015036", "gene_names_uniprotkb": "HSP33", "gene_names_refseq": "HSP33", "protein_names_uniprotkb": "Probable glutathione-independent glyoxalase HSP33; 4.2.1.130; Glyoxalase 3 homolog 3; Heat shock protein 33", "protein_names_refseq": "glutathione-independent methylglyoxalase family protein", "tax_id": 559292, "disease": "Parkinson's disease (Disease Ontology:DOID:14330); cancer (Disease Ontology:DOID:162)", "pathway": " (sce:YOR391C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14745011;21139195;24374639;24706893;9169874", "class_list": "", "function": "Catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step. May play a role in detoxifying endogenously produced glyoxals. Involved in protection against reactive oxygen species (ROS) (By similarity). Important for viability in stationary phase. May negatively regulate TORC1 in response to nutrient limitation (PubMed:24706893)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W384", "ec_number_list": "4.2.1.130", "go_molecular_function": "GO:0044183 protein folding chaperone;GO:0019172 glyoxalase III activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0000932 P-body", "go_biological_process": "GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione;GO:0006457 protein folding;GO:0031669 cellular response to nutrient levels", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q08914-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08925-1", "uniprot_id": "MRN1_YEAST", "mass": 68664.0, "length": 612, "protein_name": "RNA-binding protein MRN1", "gene_name": "MRN1", "organism": "Yeast", "refseq_name": "Mrn1p", "refseq_ac": "NP_015140", "gene_names_uniprotkb": "MRN1; PTR69", "gene_names_refseq": "MRN1; PTR69", "protein_names_uniprotkb": "RNA-binding protein MRN1; Multicopy suppressor of RSC-NHP6 synthetic lethality protein 1; Post-transcriptional regulator of 69 kDa", "protein_names_refseq": "Mrn1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL184C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562095;14562106;18407956;18959479;20959291;24374639;32597660;33491328;9169875", "class_list": "", "function": "RNA-binding protein that binds specific categories of mRNAs, including those that contain upstream open reading frames (uORFs) and internal ribosome entry sites (IRES). Probably involved in translational regulation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3I4", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0003730 mRNA 3'-UTR binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000932 P-body;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006417 regulation of translation;GO:0000398 mRNA splicing, via spliceosome;GO:0061158 3'-UTR-mediated mRNA destabilization;GO:1990394 cellular response to cell wall damage", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q08925-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08929-1", "uniprot_id": "GUP2_YEAST", "mass": 71289.0, "length": 609, "protein_name": "Membrane-bound O-acyltransferase GUP2", "gene_name": "GUP2", "organism": "Yeast", "refseq_name": "putative O-acyltransferase", "refseq_ac": "NP_015135", "gene_names_uniprotkb": "GUP2", "gene_names_refseq": "GUP2", "protein_names_uniprotkb": "Membrane-bound O-acyltransferase GUP2; Glycerol uptake protein 2", "protein_names_refseq": "putative O-acyltransferase", "tax_id": 559292, "disease": "chondrodysplasia-pseudohermaphroditism syndrome (Disease Ontology:DOID:0060644)", "pathway": " (sce:YPL189W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "10931309;15278288;15381122;24374639;25589358;26928762;33481703;33491328;9169875", "class_list": "", "function": "Probable membrane-bound O-acyltransferase (By similarity). Together with GUP1, has an influence on the chemical composition of the yeast extracellular matrix (yECM) in yeast multicellular aggregates, such as biofilms and colonies (PubMed:25589358)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3I0", "ec_number_list": "", "go_molecular_function": "GO:0015293 symporter activity;GO:0008374 O-acyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0015793 glycerol transmembrane transport;GO:0071475 cellular hyperosmotic salinity response;GO:0006506 GPI anchor biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q08929-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08930-1", "uniprot_id": "YP191_YEAST", "mass": 41032.0, "length": 360, "protein_name": "Ubiquitin carboxyl-terminal hydrolase MIY1", "gene_name": "", "organism": "Yeast", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase MIY1; 3.4.19.12; Deubiquitinating enzyme MIY1", "protein_names_refseq": "", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL191C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "14562095;14562106;17563356;18407956;19779198;20702584;24374639;27292798;32597660;33481703;33491328;9169875", "class_list": "", "function": "Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has endodeubiquitinase activity., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3H7", "ec_number_list": "", "go_molecular_function": "GO:0016807 cysteine-type carboxypeptidase activity;GO:0004843 cysteine-type deubiquitinase activity;GO:1990380 K48-linked deubiquitinase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0071944 cell periphery", "go_biological_process": "GO:0006508 proteolysis;GO:0071108 protein K48-linked deubiquitination;GO:0071444 cellular response to pheromone", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q08930-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08932-1", "uniprot_id": "RSA1_YEAST", "mass": 43998.0, "length": 381, "protein_name": "Ribosome assembly 1 protein", "gene_name": "RSA1", "organism": "Yeast", "refseq_name": "Rsa1p", "refseq_ac": "NP_015131", "gene_names_uniprotkb": "RSA1", "gene_names_refseq": "RSA1", "protein_names_uniprotkb": "Ribosome assembly 1 protein", "protein_names_refseq": "Rsa1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL193W)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10567587;14562106;18407956;19779198;19795423;19823750;22814378;23749301;24374639;33229814;33481703;33491328;34965436;9169875", "class_list": "", "function": "Involved in a late nucleoplasmic step of 60S ribosomal subunit assembly., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 9, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 9, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 9, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "D6W3H5", "ec_number_list": "", "go_molecular_function": "GO:0043022 ribosome binding", "go_cellular_component": "GO:0005654 nucleoplasm", "go_biological_process": "GO:0000492 box C/D snoRNP assembly;GO:0000027 ribosomal large subunit assembly;GO:0034517 ribophagy", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "Q08932-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08957-1", "uniprot_id": "AFT2_YEAST", "mass": 47105.0, "length": 416, "protein_name": "Iron-regulated transcriptional activator AFT2", "gene_name": "AFT2", "organism": "Yeast", "refseq_name": "Aft2p", "refseq_ac": "NP_015122", "gene_names_uniprotkb": "AFT2", "gene_names_refseq": "AFT2", "protein_names_uniprotkb": "Iron-regulated transcriptional activator AFT2; Activator of iron transcription protein 2", "protein_names_refseq": "Aft2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL202C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "11448968;11734641;12756250;15649888;16024809;24374639;24591629;33491328;33502312;9169875", "class_list": "", "function": "Transcription factor required for iron homeostasis and resistance to oxidative stress (PubMed:11448968, PubMed:11734641, PubMed:12756250, PubMed:15649888, PubMed:16024809). With AFT1, activates the gene expression in response to low-iron conditions, also called iron regulon (PubMed:11448968, PubMed:11734641, PubMed:12756250, PubMed:15649888, PubMed:16024809, PubMed:24591629). Recognizes the consensus iron-responsive element (Fe-RE) sequence 5'-CACCC-3' in the promoters of target genes (PubMed:24591629). The transcription activation by AFT1 and AFT2 depends on the mitochondrial iron-sulfur protein biosynthesis pathway (PubMed:15649888). In high iron condition, the presence of iron leads to dimerization, which in turn leads to a decrease in DNA affinity (PubMed:24591629)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W3G7", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0051536 iron-sulfur cluster binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006879 intracellular iron ion homeostasis;GO:0032048 cardiolipin metabolic process;GO:0010106 cellular response to iron ion starvation", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q08957-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08961-1", "uniprot_id": "RKM1_YEAST", "mass": 67178.0, "length": 583, "protein_name": "Ribosomal lysine N-methyltransferase 1", "gene_name": "RKM1", "organism": "Yeast", "refseq_name": "protein-lysine N-methyltransferase", "refseq_ac": "NP_015116", "gene_names_uniprotkb": "RKM1", "gene_names_refseq": "RKM1", "protein_names_uniprotkb": "Ribosomal lysine N-methyltransferase 1; 2.1.1.-", "protein_names_refseq": "protein-lysine N-methyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL208W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "14562095;14562106;16096273;17327221;18407956;21177495;22522802;24374639;29183786;33491328;9169875", "class_list": "", "function": "S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that monomethylates ribosomal protein S18 (RPS18A and RPS18B) at 'Lys-48' and dimethylates ribosomal protein L23 (RPL23A and RPL23B) at 'Lys-106' and 'Lys-110'., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3G2", "ec_number_list": "", "go_molecular_function": "GO:0016279 protein-lysine N-methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0018026 peptidyl-lysine monomethylation;GO:0018027 peptidyl-lysine dimethylation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q08961-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08963-1", "uniprot_id": "RU2A_YEAST", "mass": 27193.0, "length": 238, "protein_name": "U2 small nuclear ribonucleoprotein A'", "gene_name": "LEA1", "organism": "Yeast", "refseq_name": "U2 snRNP complex subunit LEA1", "refseq_ac": "NP_015111", "gene_names_uniprotkb": "LEA1", "gene_names_refseq": "LEA1", "protein_names_uniprotkb": "U2 small nuclear ribonucleoprotein A'; Looks exceptionally like U2A protein 1; U2 snRNP A'", "protein_names_refseq": "U2 snRNP complex subunit LEA1", "tax_id": 559292, "disease": "azoospermia (Disease Ontology:DOID:14227); connective tissue disease (Disease Ontology:DOID:65)", "pathway": " (sce:YPL213W)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "11884590;14562095;14562106;14690591;16618970;17322287;24374639;27445308;27459055;27980089;28076345;28530653;28919079;29146870;29146871;29153833;29794219;29995849;30879786;33491328;34349264;9169875;9799242", "class_list": "", "function": "Involved in pre-mRNA splicing and associates with U2 snRNA in an MSL1-dependent manner. Required for the normal accumulation of U2 snRNA, as well as for spliceosome assembly and the efficient recruitment of U2 snRNP to the pre-mRNA (PubMed:9799242). Pre-mRNA splicing is carried out by the spliceosome, a highly dynamic complex that undergoes significant compositional and conformational changes throughout the splicing cycle. 10 conformational states of the spliceosome are named as early complex (E), pre-spliceosome (A), precursor of the pre-catalytic spliceosome (pre-B), pre-catalytic spliceosome (B), activated spliceosome (B(act)), catalytically activated complex (B*), catalytic step I complex (C), step II catalytically activated complex (C*), post-catalytic spliceosome (P), and intron lariat spliceosome (ILS). In the early complex (E), U1 snRNP recognizes the 5' splice site of the pre-mRNA. Subsequently, U2 snRNP binds stably to the branch site region, forming the pre-spliceosome (A). The U4/U5/U6 tri-snRNP then joins to create the pre-B complex. Following several rearrangements, U1 and U4 snRNPs are released, resulting in the formation of the catalytically active spliceosome (B(act)) (PubMed:16618970). Splicing proceeds through 2 sequential transesterification reactions, which result in the removal of the intervening RNA sequences between 2 target exons. In the branching reaction, the 2'-hydroxyl group of the branch point adenosine attacks the 5' splice site, cleaving the RNA and generating a lariat intermediate. In the exon ligation recation, the 3'-hydroxyl group of the upstream exon attacks the 3' splice site, leading to exon ligation and release of the intron lariat. These steps occur spontaneously within the B* and C* complexes, respectively. The transitions from B(act) to B*, and from C to C*, are driven by the ATPase/helicases PRP2 and PRP16, respectively (PubMed:27445308, PubMed:27459055, PubMed:27980089, PubMed:28076345, PubMed:28530653, PubMed:28919079, PubMed:29146870, PubMed:29146871, PubMed:29153833, PubMed:29794219, PubMed:29995849, PubMed:30879786, PubMed:34349264)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3F7", "ec_number_list": "", "go_molecular_function": "GO:0030620 U2 snRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005686 U2 snRNP;GO:0071004 U2-type prespliceosome", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:1903241 U2-type prespliceosome assembly", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "Q08963-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08977-1", "uniprot_id": "CUB1_YEAST", "mass": 62780.0, "length": 551, "protein_name": "Cu(2+) suppressing and bleomycin sensitive protein 1", "gene_name": "CUB1", "organism": "Yeast", "refseq_name": "Cub1p", "refseq_ac": "NP_015063", "gene_names_uniprotkb": "CUB1", "gene_names_refseq": "CUB1", "protein_names_uniprotkb": "Cu(2+) suppressing and bleomycin sensitive protein 1", "protein_names_refseq": "Cub1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL260W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "14562095;16172400;17563356;18407956;19779198;21177495;22842922;23749301;24374639;3040736;33491328;9169875", "class_list": "", "function": "Involved in bleomycin tolerance with links to DNA repair and/or proteasome function., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3A9;Q05760;Q7LGU3", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q08977-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08991-1", "uniprot_id": "FEX2_YEAST", "mass": 41971.0, "length": 375, "protein_name": "Fluoride export protein 2", "gene_name": "FEX2", "organism": "Yeast", "refseq_name": "fluoride transporter", "refseq_ac": "NP_015044", "gene_names_uniprotkb": "FEX2", "gene_names_refseq": "FEX2", "protein_names_uniprotkb": "Fluoride export protein 2", "protein_names_refseq": "fluoride transporter", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL279C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "21126336;24173035;24374639;26055717;9169875", "class_list": "", "function": "Fluoride channel required for the rapid expulsion of cytoplasmic fluoride., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6W393", "ec_number_list": "", "go_molecular_function": "GO:1903425 fluoride transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery", "go_biological_process": "GO:1903424 fluoride transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q08991-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12000-1", "uniprot_id": "TMA46_YEAST", "mass": 39514.0, "length": 345, "protein_name": "Translation machinery-associated protein 46", "gene_name": "TMA46", "organism": "Yeast", "refseq_name": "translation machinery-associated protein TMA46", "refseq_ac": "NP_014734", "gene_names_uniprotkb": "TMA46; DFRP1; YOR3160w", "gene_names_refseq": "TMA46", "protein_names_uniprotkb": "Translation machinery-associated protein 46; DRG family-regulatory protein 1", "protein_names_refseq": "translation machinery-associated protein TMA46", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR091W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "14562095;14562106;15676025;15905473;16702403;19448108;19779198;24374639;32597660;33491328;9169874;9200815", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2F2", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q12000-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12004-1", "uniprot_id": "TFB4_YEAST", "mass": 37457.0, "length": 338, "protein_name": "General transcription and DNA repair factor IIH subunit TFB4", "gene_name": "TFB4", "organism": "Yeast", "refseq_name": "TFIIH/NER complex subunit TFB4", "refseq_ac": "NP_015381", "gene_names_uniprotkb": "TFB4", "gene_names_refseq": "TFB4", "protein_names_uniprotkb": "General transcription and DNA repair factor IIH subunit TFB4; RNA polymerase II transcription factor B 34 kDa subunit; RNA polymerase II transcription factor B p34 subunit; RNA polymerase II transcription factor B subunit 4; TFIIH subunit TFB4", "protein_names_refseq": "TFIIH/NER complex subunit TFB4", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR056W); (R-SCE-113418); (R-SCE-674695); (R-SCE-6781823); (R-SCE-6782135); (R-SCE-6782210); (R-SCE-6796648); (R-SCE-72086); (R-SCE-73772); (R-SCE-73776); (R-SCE-73779); (R-SCE-75953); (R-SCE-76042); (R-SCE-77075)", "pathway_count": 14, "publication_count": 16, "publication_id_list": "10506223;14500720;22411836;22814378;24374639;29088706;30472190;34099686;34133942;35051353;36411341;37014863;7961739;8631896;9169875;9235928", "class_list": "", "function": "Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W462", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0016251 RNA polymerase II general transcription initiation factor activity", "go_cellular_component": "GO:0005675 transcription factor TFIIH holo complex;GO:0000112 nucleotide-excision repair factor 3 complex;GO:0000439 transcription factor TFIIH core complex", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0006366 transcription by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter;GO:0006289 nucleotide-excision repair", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q12004-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12008-1", "uniprot_id": "PMG2_YEAST", "mass": 36073.0, "length": 311, "protein_name": "Phosphoglycerate mutase 2", "gene_name": "GPM2", "organism": "Yeast", "refseq_name": "phosphoglycerate mutase family protein GPM2", "refseq_ac": "NP_010263", "gene_names_uniprotkb": "GPM2; D2835", "gene_names_refseq": "GPM2", "protein_names_uniprotkb": "Phosphoglycerate mutase 2; 5.4.2.11; BPG-dependent PGAM 2; MPGM 2; PGAM 2; Phosphoglyceromutase 2", "protein_names_refseq": "phosphoglycerate mutase family protein GPM2", "tax_id": 559292, "disease": "myoglobinuria (Disease Ontology:DOID:0080108); familial erythrocytosis 8 (Disease Ontology:DOID:0111630)", "pathway": " (sce:YDL021W); (R-SCE-70171); (R-SCE-70263)", "pathway_count": 3, "publication_count": 9, "publication_id_list": "11502169;14562106;17322287;18407956;24146988;24374639;33491328;9169867;9544241", "class_list": "", "function": "Could be non-functional., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRW9", "ec_number_list": "5.4.2.11", "go_molecular_function": "GO:0004619 phosphoglycerate mutase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0061621 canonical glycolysis", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q12008-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12010-1", "uniprot_id": "YPQ1_YEAST", "mass": 34873.0, "length": 308, "protein_name": "Vacuolar lysine transporter YPQ1", "gene_name": "YPQ1", "organism": "Yeast", "refseq_name": "cationic amino acid transporter", "refseq_ac": "NP_014549", "gene_names_uniprotkb": "YPQ1; O0929", "gene_names_refseq": "YPQ1", "protein_names_uniprotkb": "Vacuolar lysine transporter YPQ1; PQ-loop repeat-containing protein 1", "protein_names_refseq": "cationic amino acid transporter", "tax_id": 559292, "disease": "lysosomal storage disease (Disease Ontology:DOID:3211)", "pathway": " (sce:YOL092W)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "14562095;14562106;16847258;18407956;19779198;21126336;22218487;22814378;23169667;24374639;25229858;32776922;33481703;33491328;8533473;9169874", "class_list": "", "function": "Amino acid transporter that moves lysine into the vacuole (PubMed:25229858). May also contribute to low affinity arginine import into the vacuole (PubMed:32776922). Has also been suggested to mediate export of cationic amino acids from the vacuole (PubMed:23169667). May function as an amino acid/proton antiporter (PubMed:25229858)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6W1X6", "ec_number_list": "", "go_molecular_function": "GO:0015174 basic amino acid transmembrane transporter activity;GO:0015189 L-lysine transmembrane transporter activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0034488 basic amino acid transmembrane export from vacuole;GO:0090517 L-lysine transmembrane import into vacuole", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q12010-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12013-1", "uniprot_id": "AKR2_YEAST", "mass": 85236.0, "length": 749, "protein_name": "Probable palmitoyltransferase AKR2", "gene_name": "AKR2", "organism": "Yeast", "refseq_name": "putative palmitoyltransferase AKR2", "refseq_ac": "NP_014677", "gene_names_uniprotkb": "AKR2; OR26.25", "gene_names_refseq": "AKR2", "protein_names_uniprotkb": "Probable palmitoyltransferase AKR2; 2.3.1.225; Ankyrin repeat-containing protein AKR2", "protein_names_refseq": "putative palmitoyltransferase AKR2", "tax_id": 559292, "disease": "Huntington's disease (Disease Ontology:DOID:12858)", "pathway": " (sce:YOR034C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "12748633;14562106;16847258;19684113;24374639;9169874;9243510", "class_list": "", "function": "May be involved in constitutive endocytosis of a-factor receptor STE3., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W2A0", "ec_number_list": "2.3.1.225", "go_molecular_function": "GO:0019706 protein-cysteine S-palmitoyltransferase activity;GO:0016409 palmitoyltransferase activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0000329 fungal-type vacuole membrane;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0018345 protein palmitoylation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q12013-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12015-1", "uniprot_id": "DSC3_YEAST", "mass": 32935.0, "length": 292, "protein_name": "DSC E3 ubiquitin ligase complex subunit 3", "gene_name": "DSC3", "organism": "Yeast", "refseq_name": "Dsc3p", "refseq_ac": "NP_014866", "gene_names_uniprotkb": "DSC3; YOR50-13", "gene_names_refseq": "DSC3", "protein_names_uniprotkb": "DSC E3 ubiquitin ligase complex subunit 3; Defective for SREBP cleavage protein 3", "protein_names_refseq": "Dsc3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR223W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "16847258;21777356;24374639;25078903;29355480;33491328;8840505;9169874", "class_list": "", "function": "Component of the DSC E3 ubiquitin ligase complexes that tag proteins present in Golgi, endosome and vacuole membranes and function in protein homeostasis under non-stress conditions and support a role in protein quality control (PubMed:25078903, PubMed:29355480). Involved in endocytic protein trafficking (PubMed:21777356)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 6, "predicted_n_glycosites": 5, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "D6W2S8", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0000328 fungal-type vacuole lumen;GO:0044695 Dsc E3 ubiquitin ligase complex", "go_biological_process": "GO:0006897 endocytosis;GO:0015031 protein transport;GO:0016567 protein ubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0140624 EGAD pathway", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q12015-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12016-1", "uniprot_id": "VPS68_YEAST", "mass": 20101.0, "length": 184, "protein_name": "Vacuolar protein sorting-associated protein 68", "gene_name": "VPS68", "organism": "Yeast", "refseq_name": "Vps68p", "refseq_ac": "NP_014512", "gene_names_uniprotkb": "VPS68", "gene_names_refseq": "VPS68", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 68", "protein_names_refseq": "Vps68p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL129W)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "12134085;14562095;14562106;14576278;15665377;17322287;18407956;19779198;22218487;22814378;23749301;24374639;32597660;33481703;33491328;8896265;9169874", "class_list": "", "function": "Involved in vacuolar protein sorting., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W1T9", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005768 endosome;GO:0000329 fungal-type vacuole membrane;GO:0034424 Vps55/Vps68 complex", "go_biological_process": "GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway;GO:0006623 protein targeting to vacuole", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q12016-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12025-1", "uniprot_id": "EMC10_YEAST", "mass": 22769.0, "length": 205, "protein_name": "Endoplasmic reticulum membrane protein complex subunit 10", "gene_name": "EMC10", "organism": "Yeast", "refseq_name": "Emc10p", "refseq_ac": "NP_010341", "gene_names_uniprotkb": "EMC10; D4219", "gene_names_refseq": "EMC10", "protein_names_uniprotkb": "Endoplasmic reticulum membrane protein complex subunit 10", "protein_names_refseq": "Emc10p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR056C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562095;14562106;17322287;24374639;26512320;29809151;8789263;9169867", "class_list": "", "function": "Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins (PubMed:29809151). Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues (PubMed:29809151). Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices (PubMed:29809151). It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes. By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins (By similarity)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 1, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VS42", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0072546 EMC complex;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q12025-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12029-1", "uniprot_id": "FSF1_YEAST", "mass": 35414.0, "length": 327, "protein_name": "Sideroflexin FSF1", "gene_name": "FSF1", "organism": "Yeast", "refseq_name": "Fsf1p", "refseq_ac": "NP_014914", "gene_names_uniprotkb": "FSF1", "gene_names_refseq": "FSF1", "protein_names_uniprotkb": "Sideroflexin FSF1; Fungal sideroflexin-1", "protein_names_refseq": "Fsf1p", "tax_id": 559292, "disease": "combined oxidative phosphorylation deficiency 18 (Disease Ontology:DOID:0111484)", "pathway": " (sce:YOR271C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562095;14562106;16823961;17240176;21126336;22814378;24374639;30442778;8896271;9169874", "class_list": "", "function": "Mitochondrial amino-acid transporter that mediates transport of serine into mitochondria., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2X1", "ec_number_list": "", "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0015194 L-serine transmembrane transporter activity;GO:0015075 monoatomic ion transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0071454 cellular response to anoxia;GO:0006730 one-carbon metabolic process;GO:1990542 mitochondrial transmembrane transport;GO:0140300 serine import into mitochondrion", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q12029-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12031-1", "uniprot_id": "ACEB_YEAST", "mass": 64976.0, "length": 575, "protein_name": "Mitochondrial 2-methylisocitrate lyase ICL2", "gene_name": "ICL2", "organism": "Yeast", "refseq_name": "methylisocitrate lyase ICL2", "refseq_ac": "NP_015331", "gene_names_uniprotkb": "ICL2; LPZ6C; YP9723.06C", "gene_names_refseq": "ICL2", "protein_names_uniprotkb": "Mitochondrial 2-methylisocitrate lyase ICL2; 4.1.3.30; Methylisocitrate lyase", "protein_names_refseq": "methylisocitrate lyase ICL2", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR006C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "11092862;14562095;14562106;14576278;24374639;33491328;8923733;9169875", "class_list": "", "function": "Catalyzes the formation of pyruvate and succinate from 2-methylisocitrate during the metabolism of endogenous propionyl-CoA. Does not act on isocitrate., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W417", "ec_number_list": "4.1.3.1;4.1.3.30", "go_molecular_function": "GO:0004451 isocitrate lyase activity;GO:0046421 methylisocitrate lyase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0019629 propionate catabolic process, 2-methylcitrate cycle", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q12031-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12034-1", "uniprot_id": "SLF1_YEAST", "mass": 50943.0, "length": 447, "protein_name": "Protein SLF1", "gene_name": "SLF1", "organism": "Yeast", "refseq_name": "Slf1p", "refseq_ac": "NP_010803", "gene_names_uniprotkb": "SLF1; D9719.20", "gene_names_refseq": "SLF1; SRO99", "protein_names_uniprotkb": "Protein SLF1", "protein_names_refseq": "Slf1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR515W)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "14562106;15665377;17322287;18407956;19779198;20702584;21126336;21177495;23749301;24374639;32597660;33491328;8628314;9169867", "class_list": "", "function": "Regulates the copper-dependent mineralization of copper sulfide complexes on the cell surface in cells cultured in medium containing copper salts., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VTD6;E9P8Z6", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0003729 mRNA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0006417 regulation of translation;GO:0006878 intracellular copper ion homeostasis;GO:0045727 positive regulation of translation", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q12034-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12035-1", "uniprot_id": "FCF2_YEAST", "mass": 25636.0, "length": 217, "protein_name": "rRNA-processing protein FCF2", "gene_name": "FCF2", "organism": "Yeast", "refseq_name": "Fcf2p", "refseq_ac": "NP_013152", "gene_names_uniprotkb": "FCF2; L2128", "gene_names_refseq": "FCF2", "protein_names_uniprotkb": "rRNA-processing protein FCF2; FAF1 copurifying factor 2", "protein_names_refseq": "Fcf2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR051C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562095;16762320;19779198;22814378;24374639;33481703;33491328;9169871", "class_list": "", "function": "Essential protein involved in pre-rRNA processing and 40S ribosomal subunit assembly. Required for the early cleavage steps of 35S rRNA at the A(0), A(1), and A(2) sites., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VY53", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus", "go_biological_process": "GO:0006396 RNA processing;GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0030490 maturation of SSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q12035-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12040-1", "uniprot_id": "YO283_YEAST", "mass": 26177.0, "length": 230, "protein_name": "Broad-specificity phosphatase YOR283W", "gene_name": "", "organism": "Yeast", "refseq_name": "phosphoglycerate mutase", "refseq_ac": "NP_014926", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Broad-specificity phosphatase YOR283W; 3.1.3.-", "protein_names_refseq": "phosphoglycerate mutase", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR283W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "14562095;14562106;19753119;19795423;19823750;20427268;23749301;24374639;33481703;33491328;8896271;9169874", "class_list": "", "function": "Metal-independent phosphatase active against a broad range of phosphorylated substrates including nucleoside tri- and diphosphates, phosphorylated organic acids, and amino acids. Shows no activity against phytic acid, phosphorylated carbohydrates, and nucleoside monophosphates., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2Y1", "ec_number_list": "", "go_molecular_function": "GO:0016791 phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0016311 dephosphorylation", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q12040-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12048-1", "uniprot_id": "ATG41_YEAST", "mass": 14986.0, "length": 136, "protein_name": "Autophagy-related protein 41", "gene_name": "ATG41", "organism": "Yeast", "refseq_name": "Atg41p", "refseq_ac": "NP_015073", "gene_names_uniprotkb": "ATG41; ICY2", "gene_names_refseq": "ATG41; ICY2", "protein_names_uniprotkb": "Autophagy-related protein 41; Interacting with cytoskeleton protein 2", "protein_names_refseq": "Atg41p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL250C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "14562106;17322287;18407956;19779198;24374639;26565778;29321173;31462158;33491328;39917769;9169875", "class_list": "", "function": "Involved in both autophagy and sulfur metabolism during zinc deficiency (PubMed:26565778, PubMed:29321173, PubMed:39917769). Does not appear to play a role in determining the size of autophagosomes, but rather influences their formation rate (PubMed:26565778). With ATG9, plays a role in the delivery of donor membrane to expanding phagophore (PubMed:26565778). Required for growth in zinc-deficient conditions, but not when zinc is abundant or when other metals are limiting. This function in growing during zinc deficiency is independent on macroautophagy, but linked to sulfur metabolism since ATG41 is required for the normal accumulation of methionine, homocysteine, and cysteine in zinc-deficient cells (PubMed:29321173)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3C0", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0034045 phagophore assembly site membrane", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0016236 macroautophagy;GO:0000422 autophagy of mitochondrion;GO:0006995 cellular response to nitrogen starvation;GO:0032258 cytoplasm to vacuole targeting by the Cvt pathway", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q12048-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12049-1", "uniprot_id": "THP3_YEAST", "mass": 53719.0, "length": 470, "protein_name": "Protein THP3", "gene_name": "THP3", "organism": "Yeast", "refseq_name": "Thp3p", "refseq_ac": "NP_015370", "gene_names_uniprotkb": "THP3; YP9499.03c", "gene_names_refseq": "THP3", "protein_names_uniprotkb": "Protein THP3; THO-related protein 3", "protein_names_refseq": "Thp3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR045C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "14562095;14562106;18407956;19061648;19289793;19779198;21149575;22814378;23749301;24374639;33491328;9169875", "class_list": "", "function": "Forms a complex with CSN12 that is recruited to transcribed genes and required for transcription elongation. May also be involved in pre-mRNA splicing., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W453;Q07109", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0000791 euchromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q12049-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12056-1", "uniprot_id": "ISU2_YEAST", "mass": 16930.0, "length": 156, "protein_name": "Iron sulfur cluster assembly protein 2, mitochondrial", "gene_name": "ISU2", "organism": "Yeast", "refseq_name": "putative iron-binding protein ISU2", "refseq_ac": "NP_014869", "gene_names_uniprotkb": "ISU2; NUA2", "gene_names_refseq": "ISU2; NUA2", "protein_names_uniprotkb": "Iron sulfur cluster assembly protein 2, mitochondrial; Iron sulfur cluster scaffold protein 2", "protein_names_refseq": "putative iron-binding protein ISU2", "tax_id": 559292, "disease": "pre-eclampsia (Disease Ontology:DOID:10591); clear cell renal cell carcinoma (Disease Ontology:DOID:4467); mitochondrial myopathy (Disease Ontology:DOID:699)", "pathway": " (sce:YOR226C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "10468587;10588895;14562106;15143178;23615440;24374639;27738674;31040179;8840505;9169874", "class_list": "", "function": "Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins (By similarity). First, a [2Fe-2S] cluster is transiently assembled on the scaffold proteins ISU1 and ISU2 (By similarity). In a second step, the cluster is released from ISU1/ISU2, transferred to glutaredoxin GRX5, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins (By similarity). Cluster assembly on ISU1/ISU2 depends on the function of the cysteine desulfurase complex NFS1-ISD11, which serves as the sulfur donor for cluster synthesis, the iron-binding protein frataxin (YFH1) as the putative iron donor, and the electron transfer chain comprised of ferredoxin reductase ARH1 and ferredoxin YAH1, which receive their electrons from NADH (By similarity). Fe-S cluster release from ISU1/ISU2 is achieved by interaction with the Hsp70 chaperone SSQ1, assisted by the DnaJ-like co-chaperone JAC1 and the nucleotide exchange factor MGE1 (PubMed:23615440). ISU1 is the major isoform in yeast, while ISU2 is not detectable in cells grown to stationary phase (PubMed:10588895). Also involved in production of a sulfur precursor required for thiolation of cytoplasmic tRNAs (PubMed:31040179)., [UniProtKB, UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2T0", "ec_number_list": "", "go_molecular_function": "GO:0051537 2 iron, 2 sulfur cluster binding;GO:0008198 ferrous iron binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0016226 iron-sulfur cluster assembly;GO:0006879 intracellular iron ion homeostasis;GO:0002098 tRNA wobble uridine modification", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q12056-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12059-1", "uniprot_id": "ULA1_YEAST", "mass": 52853.0, "length": 462, "protein_name": "NEDD8-activating enzyme E1 regulatory subunit", "gene_name": "ULA1", "organism": "Yeast", "refseq_name": "Ula1p", "refseq_ac": "NP_015322", "gene_names_uniprotkb": "ULA1; ENR2; LPA14W", "gene_names_refseq": "ENR2; ULA1", "protein_names_uniprotkb": "NEDD8-activating enzyme E1 regulatory subunit; E1 N-terminus-related protein 2; Ubiquitin-activating enzyme E1-like 1; Ubiquitin-like activation protein 1", "protein_names_refseq": "Ula1p", "tax_id": 559292, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); middle cerebral artery infarction (Disease Ontology:DOID:3525)", "pathway": " (sce:YPL003W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "24374639;9169875;9531531;9545234", "class_list": "", "function": "Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme. E1 activates NEDD8/RUB1 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBC12., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W409", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0019781 NEDD8 activating enzyme activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0045116 protein neddylation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q12059-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12066-1", "uniprot_id": "NUR1_YEAST", "mass": 56887.0, "length": 484, "protein_name": "Nuclear rim protein 1", "gene_name": "NUR1", "organism": "Yeast", "refseq_name": "Nur1p", "refseq_ac": "NP_010194", "gene_names_uniprotkb": "NUR1; D2416", "gene_names_refseq": "NUR1", "protein_names_uniprotkb": "Nuclear rim protein 1", "protein_names_refseq": "Nur1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL089W)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "14562095;14562106;15023545;17287358;17330950;18407956;18997772;19520826;19779198;19795423;19823750;21126336;23749301;24374639;32597660;33481703;33491328;8923743;9169867", "class_list": "", "function": "Member of a perinuclear network that controls recombination at multiple loci to maintain genome stability. Required for rDNA repeat stability., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 23, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRQ9", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0031965 nuclear membrane;GO:0034399 nuclear periphery", "go_biological_process": "GO:0007096 regulation of exit from mitosis;GO:0043007 maintenance of rDNA", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "Q12066-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12067-1", "uniprot_id": "ATX2_YEAST", "mass": 34408.0, "length": 313, "protein_name": "Metal homeostasis factor ATX2", "gene_name": "ATX2", "organism": "Yeast", "refseq_name": "Mn(2+) transporter ATX2", "refseq_ac": "NP_014722", "gene_names_uniprotkb": "ATX2; YOR29-30", "gene_names_refseq": "ATX2; YOR29-30", "protein_names_uniprotkb": "Metal homeostasis factor ATX2", "protein_names_refseq": "Mn(2+) transporter ATX2", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR079C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "16847258;17322287;24374639;33491328;8887660;9133743;9169874", "class_list": "", "function": "Functions in the homeostasis of manganese ions., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2E2", "ec_number_list": "", "go_molecular_function": "GO:0005385 zinc ion transmembrane transporter activity;GO:0005384 manganese ion transmembrane transporter activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0005770 late endosome;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0071577 zinc ion transmembrane transport;GO:0030026 intracellular manganese ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q12067-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12069-1", "uniprot_id": "PUS9_YEAST", "mass": 53399.0, "length": 462, "protein_name": "tRNA pseudouridine(32) synthase, mitochondrial", "gene_name": "PUS9", "organism": "Yeast", "refseq_name": "pseudouridine synthase PUS9", "refseq_ac": "NP_010248", "gene_names_uniprotkb": "PUS9; D2743", "gene_names_refseq": "PUS9", "protein_names_uniprotkb": "tRNA pseudouridine(32) synthase, mitochondrial; 5.4.99.28; tRNA pseudouridine synthase 9; tRNA pseudouridylate synthase 9; tRNA-uridine isomerase 9", "protein_names_refseq": "pseudouridine synthase PUS9", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL036C)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "14562106;15466869;17322287;17563356;18407956;19795423;19823750;20702584;24374639;25219674;32597660;33481703;33491328;9169867", "class_list": "", "function": "Responsible for synthesis of pseudouridine from uracil-32 in mitochondrial transfer RNAs., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRV8;Q6B2P8", "ec_number_list": "5.4.99.28;3.5.4.26", "go_molecular_function": "GO:0003723 RNA binding;GO:0009982 pseudouridine synthase activity;GO:0160151 tRNA pseudouridine(32) synthase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0031119 tRNA pseudouridine synthesis;GO:0000455 enzyme-directed rRNA pseudouridine synthesis", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q12069-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12078-1", "uniprot_id": "SMF3_YEAST", "mass": 51775.0, "length": 473, "protein_name": "Iron transporter SMF3", "gene_name": "SMF3", "organism": "Yeast", "refseq_name": "putative divalent metal ion transporter SMF3", "refseq_ac": "NP_013134", "gene_names_uniprotkb": "SMF3", "gene_names_refseq": "SMF3", "protein_names_uniprotkb": "Iron transporter SMF3", "protein_names_refseq": "putative divalent metal ion transporter SMF3", "tax_id": 559292, "disease": "restless legs syndrome (Disease Ontology:DOID:0050425); Buruli ulcer disease (Disease Ontology:DOID:0050456); inflammatory bowel disease (Disease Ontology:DOID:0050589); lymphoproliferative syndrome (Disease Ontology:DOID:0060704); Parkinsonism (Disease Ontology:DOID:0080855); leprosy (Disease Ontology:DOID:1024); urinary bladder cancer (Disease Ontology:DOID:11054); sarcoidosis (Disease Ontology:DOID:11335); iron deficiency anemia (Disease Ontology:DOID:11758); hypochromic anemia (Disease Ontology:DOID:11759); Behcet's disease (Disease Ontology:DOID:13241); Parkinson's disease (Disease Ontology:DOID:14330); duodenal ulcer (Disease Ontology:DOID:1724); brain ischemia (Disease Ontology:DOID:2316); anemia (Disease Ontology:DOID:2355); multiple sclerosis (Disease Ontology:DOID:2377); pulmonary tuberculosis (Disease Ontology:DOID:2957); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); tuberculosis (Disease Ontology:DOID:399); systemic scleroderma (Disease Ontology:DOID:418); pneumonia (Disease Ontology:DOID:552); systemic juvenile rheumatoid arthritis (Disease Ontology:DOID:676); rheumatoid arthritis (Disease Ontology:DOID:7148); gastrointestinal system disease (Disease Ontology:DOID:77); ulcerative colitis (Disease Ontology:DOID:8577); Crohn's disease (Disease Ontology:DOID:8778); systemic lupus erythematosus (Disease Ontology:DOID:9074); cutaneous leishmaniasis (Disease Ontology:DOID:9111); visceral leishmaniasis (Disease Ontology:DOID:9146); type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": " (sce:YLR034C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "10930410;11027260;14562095;18407956;21126336;24374639;32597660;33491328;34965436;9169871", "class_list": "", "function": "Has a role in controlling the cellular iron ion levels. Mobilizes vacuolar stores of iron in conditions of low iron levels., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 30, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VY36", "ec_number_list": "", "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0046872 metal ion binding;GO:0005384 manganese ion transmembrane transporter activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0034755 iron ion transmembrane transport;GO:0006879 intracellular iron ion homeostasis;GO:0006826 iron ion transport;GO:0006828 manganese ion transport;GO:0030026 intracellular manganese ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q12078-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12086-1", "uniprot_id": "DIN7_YEAST", "mass": 49034.0, "length": 430, "protein_name": "DNA damage-inducible protein DIN7", "gene_name": "DIN7", "organism": "Yeast", "refseq_name": "exodeoxyribonuclease DIN7", "refseq_ac": "NP_010549", "gene_names_uniprotkb": "DIN7; DIN3; YD9320B.02C", "gene_names_refseq": "DIN3; DIN7", "protein_names_uniprotkb": "DNA damage-inducible protein DIN7; 3.1.-.-", "protein_names_refseq": "exodeoxyribonuclease DIN7", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR263C)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "24374639;9079876;9169867", "class_list": "", "function": "5'->3' double-stranded DNA exonuclease., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSP7", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0046872 metal ion binding;GO:0035312 5'-3' DNA exonuclease activity;GO:0017108 5'-flap endonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion", "go_biological_process": "GO:0006281 DNA repair;GO:0000729 DNA double-strand break processing", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q12086-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12090-1", "uniprot_id": "REXO3_YEAST", "mass": 45880.0, "length": 404, "protein_name": "RNA exonuclease 3", "gene_name": "REX3", "organism": "Yeast", "refseq_name": "RNA exonuclease", "refseq_ac": "NP_013208", "gene_names_uniprotkb": "REX3; L2904", "gene_names_refseq": "REX3", "protein_names_uniprotkb": "RNA exonuclease 3; 3.1.-.-", "protein_names_refseq": "RNA exonuclease", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR107W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10716935;14562095;24374639;33491328;9090053;9169871", "class_list": "", "function": "3' to 5' exoribonuclease required for proper 3' end maturation of MRP RNA and of the U5L snRNA., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYA7;Q7LI70", "ec_number_list": "", "go_molecular_function": "GO:0003676 nucleic acid binding;GO:0008408 3'-5' exonuclease activity;GO:0004527 exonuclease activity;GO:0000175 3'-5'-RNA exonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0034476 U5 snRNA 3'-end processing;GO:0031125 rRNA 3'-end processing;GO:0000467 exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0043628 regulatory ncRNA 3'-end processing", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q12090-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12096-1", "uniprot_id": "GNT1_YEAST", "mass": 57578.0, "length": 491, "protein_name": "Glucose N-acetyltransferase 1", "gene_name": "GNT1", "organism": "Yeast", "refseq_name": "glucose N-acetyltransferase", "refseq_ac": "NP_014965", "gene_names_uniprotkb": "GNT1; O6145", "gene_names_refseq": "GNT1", "protein_names_uniprotkb": "Glucose N-acetyltransferase 1; 2.4.1.-; N-acetylglucosaminyltransferase", "protein_names_refseq": "glucose N-acetyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR320C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "12651885;14562095;14562106;16107716;24374639;8896266;9169874", "class_list": "", "function": "N-acetylglucosaminyltransferase involved in the Golgi-specific modification of N-linked glycans., [UniProtKB, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "D6W318", "ec_number_list": "", "go_molecular_function": "GO:0008375 acetylglucosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005774 vacuolar membrane;GO:0005797 Golgi medial cisterna", "go_biological_process": "GO:0006487 protein N-linked glycosylation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q12096-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12104-1", "uniprot_id": "SWT1_YEAST", "mass": 52374.0, "length": 458, "protein_name": "Transcriptional protein SWT1", "gene_name": "SWT1", "organism": "Yeast", "refseq_name": "mRNA-processing endoribonuclease", "refseq_ac": "NP_014809", "gene_names_uniprotkb": "SWT1; O3595", "gene_names_refseq": "SWT1", "protein_names_uniprotkb": "Transcriptional protein SWT1; Synthetically lethal with TREX protein 1", "protein_names_refseq": "mRNA-processing endoribonuclease", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR166C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "16464826;17030511;21126336;23749301;24374639;33481703;33491328;8972579;9169874", "class_list": "", "function": "Involved in transcription. Probably functions as a transcriptional activator., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2M4", "ec_number_list": "", "go_molecular_function": "GO:0004521 RNA endonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0071032 nuclear mRNA surveillance of mRNP export", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q12104-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12107-1", "uniprot_id": "APC9_YEAST", "mass": 30856.0, "length": 265, "protein_name": "Anaphase-promoting complex subunit 9", "gene_name": "APC9", "organism": "Yeast", "refseq_name": "anaphase promoting complex subunit 9", "refseq_ac": "NP_013203", "gene_names_uniprotkb": "APC9", "gene_names_refseq": "APC9", "protein_names_uniprotkb": "Anaphase-promoting complex subunit 9", "protein_names_refseq": "anaphase promoting complex subunit 9", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR102C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562095;24374639;33481703;33491328;9169871;9469814", "class_list": "", "function": "Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome. In early mitosis, the APC/C is activated by CDC20 and targets securin PDS1, the B-type cyclin CLB5, and other anaphase inhibitory proteins for proteolysis, thereby triggering the separation of sister chromatids at the metaphase-to-anaphase transition. In late mitosis and in G1, degradation of CLB5 allows activation of the APC/C by CDH1, which is needed to destroy CDC20 and the B-type cyclin CLB2 to allow exit from mitosis and creating the low CDK state necessary for cytokinesis and for reforming prereplicative complexes in G1 prior to another round of replication., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYA2", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005680 anaphase-promoting complex", "go_biological_process": "GO:0051301 cell division;GO:0007346 regulation of mitotic cell cycle;GO:0016567 protein ubiquitination;GO:0006325 chromatin organization;GO:0031145 anaphase-promoting complex-dependent catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q12107-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12122-1", "uniprot_id": "HOSM_YEAST", "mass": 48594.0, "length": 440, "protein_name": "Homocitrate synthase, mitochondrial", "gene_name": "LYS21", "organism": "Yeast", "refseq_name": "homocitrate synthase LYS21", "refseq_ac": "NP_010151", "gene_names_uniprotkb": "LYS21; D2195", "gene_names_refseq": "LYS21", "protein_names_uniprotkb": "Homocitrate synthase, mitochondrial; 2.3.3.14; HCS", "protein_names_refseq": "homocitrate synthase LYS21", "tax_id": 559292, "disease": "3-hydroxy-3-methylglutaryl-CoA lyase deficiency (Disease Ontology:DOID:0070541); amino acid metabolic disorder (Disease Ontology:DOID:9252)", "pathway": " (sce:YDL131W)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "14562106;17287358;17322287;17330950;17563356;18407956;19779198;19795423;19823750;20702584;21177495;22218487;23749301;24374639;32597660;33481703;33491328;8972577;9169867", "class_list": "", "function": "Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate. Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRL8;E9P8Z7", "ec_number_list": "2.3.3.14", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004410 homocitrate synthase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion", "go_biological_process": "GO:0019878 lysine biosynthetic process via aminoadipic acid", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "Q12122-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12152-1", "uniprot_id": "YP150_YEAST", "mass": 100646.0, "length": 901, "protein_name": "Putative serine/threonine-protein kinase YPL150W", "gene_name": "", "organism": "Yeast", "refseq_name": "non-specific serine/threonine protein kinase", "refseq_ac": "NP_015175", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Putative serine/threonine-protein kinase YPL150W; 2.7.11.1", "protein_names_refseq": "non-specific serine/threonine protein kinase", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL150W); (R-SCE-1632852); (R-SCE-380972)", "pathway_count": 3, "publication_count": 21, "publication_id_list": "17287358;17330950;18407956;19684113;19779198;19795423;19823750;20489023;20702584;21126336;21177495;23749301;24374639;32597660;33229814;33481703;33491328;34965436;8948103;9169875;9990050", "class_list": "", "function": "Putative serine/threonine-protein kinase., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 14, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 14, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 14, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 53, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 13, "binding_glycan_count": 0, "secondary_ac_list": "D6W3L9", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.1.137;2.7.11.23;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0036464 cytoplasmic ribonucleoprotein granule", "go_biological_process": "GO:0006468 protein phosphorylation", "synthesized_glycan_count": 0, "hit_score": 3.7, "record_id": "Q12152-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12153-1", "uniprot_id": "SSF2_YEAST", "mass": 51856.0, "length": 453, "protein_name": "Ribosome biogenesis protein SSF2", "gene_name": "SSF2", "organism": "Yeast", "refseq_name": "rRNA-binding ribosome biosynthesis protein", "refseq_ac": "NP_010598", "gene_names_uniprotkb": "SSF2; D9740.2", "gene_names_refseq": "SSF2", "protein_names_uniprotkb": "Ribosome biogenesis protein SSF2", "protein_names_refseq": "rRNA-binding ribosome biosynthesis protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR312W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "12702244;14562106;17330950;18407956;19779198;23749301;24374639;33491328;7748491;9169867;9611192", "class_list": "", "function": "Required for biogenesis of the 60S ribosomal subunit., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VSU1", "ec_number_list": "", "go_molecular_function": "GO:0019843 rRNA binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0030687 preribosome, large subunit precursor", "go_biological_process": "GO:0000027 ribosomal large subunit assembly;GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q12153-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12156-1", "uniprot_id": "AIM7_YEAST", "mass": 17130.0, "length": 149, "protein_name": "Protein AIM7", "gene_name": "AIM7", "organism": "Yeast", "refseq_name": "Aim7p", "refseq_ac": "NP_010348", "gene_names_uniprotkb": "AIM7; D4245", "gene_names_refseq": "AIM7; GMF1", "protein_names_uniprotkb": "Protein AIM7; Altered inheritance rate of mitochondria protein 7", "protein_names_refseq": "Aim7p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR063W); (R-SCE-6798695)", "pathway_count": 2, "publication_count": 16, "publication_id_list": "14562095;14562106;17176259;18407956;19300474;19779198;19795423;19823750;21177495;22218487;22814378;24374639;33481703;33491328;8789263;9169867", "class_list": "", "function": "May be involved in mitochondrial organization and biogenesis., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS49", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0071933 Arp2/3 complex binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0030864 cortical actin cytoskeleton;GO:0030479 actin cortical patch", "go_biological_process": "GO:0071846 actin filament debranching;GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q12156-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12161-1", "uniprot_id": "PSH1_YEAST", "mass": 47068.0, "length": 406, "protein_name": "RING finger protein PSH1", "gene_name": "PSH1", "organism": "Yeast", "refseq_name": "ubiquitin-protein ligase PSH1", "refseq_ac": "NP_014587", "gene_names_uniprotkb": "PSH1; O1263", "gene_names_refseq": "PSH1", "protein_names_uniprotkb": "RING finger protein PSH1; POB3/SPT16 histone-associated protein 1", "protein_names_refseq": "ubiquitin-protein ligase PSH1", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL054W)", "pathway_count": 1, "publication_count": 25, "publication_id_list": "12242279;14562095;14562106;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20489023;20702584;21126336;21177495;22218487;22814378;23749301;24374639;25183013;30516470;32597660;33481703;33491328;8789261;9169874", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 22, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W213", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000775 chromosome, centromeric region", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 2.6, "record_id": "Q12161-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12165-1", "uniprot_id": "ATPD_YEAST", "mass": 17020.0, "length": 160, "protein_name": "ATP synthase subunit delta, mitochondrial", "gene_name": "ATP16", "organism": "Yeast", "refseq_name": "F1F0 ATP synthase subunit delta", "refseq_ac": "NP_010280", "gene_names_uniprotkb": "ATP16; D2935; YD8119.03", "gene_names_refseq": "ATP16", "protein_names_uniprotkb": "ATP synthase subunit delta, mitochondrial; F-ATPase delta subunit", "protein_names_refseq": "F1F0 ATP synthase subunit delta", "tax_id": 559292, "disease": "colitis (Disease Ontology:DOID:0060180); mitochondrial complex V (ATP synthase) deficiency nuclear type 5 (Disease Ontology:DOID:0070463); Alzheimer's disease (Disease Ontology:DOID:10652); myocardial infarction (Disease Ontology:DOID:5844); obesity (Disease Ontology:DOID:9970)", "pathway": " (sce:YDL004W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10576729;17322287;17761666;24374639;8026496;9169867", "class_list": "", "function": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRY4", "ec_number_list": "", "go_molecular_function": "GO:0046933 proton-transporting ATP synthase activity, rotational mechanism", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0045259 proton-transporting ATP synthase complex", "go_biological_process": "GO:0015986 proton motive force-driven ATP synthesis", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q12165-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12171-1", "uniprot_id": "MDM32_YEAST", "mass": 72028.0, "length": 622, "protein_name": "Mitochondrial distribution and morphology protein 32", "gene_name": "MDM32", "organism": "Yeast", "refseq_name": "Mdm32p", "refseq_ac": "NP_014790", "gene_names_uniprotkb": "MDM32; O3521", "gene_names_refseq": "MDM32", "protein_names_uniprotkb": "Mitochondrial distribution and morphology protein 32", "protein_names_refseq": "Mdm32p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR147W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "11907266;14562095;14562106;15631992;15905473;24374639;33491328;9046089;9169874", "class_list": "", "function": "Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria. Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2K4", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0007005 mitochondrion organization;GO:0006873 intracellular monoatomic ion homeostasis;GO:0000001 mitochondrion inheritance", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q12171-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12172-1", "uniprot_id": "YRR1_YEAST", "mass": 92468.0, "length": 810, "protein_name": "Zinc finger transcription factor YRR1", "gene_name": "YRR1", "organism": "Yeast", "refseq_name": "Yrr1p", "refseq_ac": "NP_014805", "gene_names_uniprotkb": "YRR1; O3571; PDR2", "gene_names_refseq": "PDR2; YRR1", "protein_names_uniprotkb": "Zinc finger transcription factor YRR1; Pleiotropic drug-resistance protein 2", "protein_names_refseq": "Yrr1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR162C)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10052137;11909958;14512416;14562095;15145054;17322287;18407956;23749301;24374639;33481703;33491328;8972579;9169874;9767597", "class_list": "", "function": "Transcription factor involved in the regulation of multidrug resistance genes. Acts in concert with YRR1., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W2M0", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0034599 cellular response to oxidative stress", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q12172-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12175-1", "uniprot_id": "MSH5_YEAST", "mass": 102209.0, "length": 901, "protein_name": "MutS protein homolog 5", "gene_name": "MSH5", "organism": "Yeast", "refseq_name": "MutS family protein MSH5", "refseq_ac": "NP_010127", "gene_names_uniprotkb": "MSH5; D1542", "gene_names_refseq": "MSH5", "protein_names_uniprotkb": "MutS protein homolog 5", "protein_names_refseq": "MutS family protein MSH5", "tax_id": 559292, "disease": "spermatogenic failure 74 (Disease Ontology:DOID:0070573); primary ovarian insufficiency 13 (Disease Ontology:DOID:0080870); lung non-small cell carcinoma (Disease Ontology:DOID:3908); primary ovarian insufficiency (Disease Ontology:DOID:5426)", "pathway": " (sce:YDL154W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "22031224;24374639;33491328;7622037;8972581;9169867;9374523", "class_list": "", "function": "Involved in meiotic recombination. Facilitate crossovers between homologs during meiosis., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRJ6", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0030983 mismatched DNA binding;GO:0140664 ATP-dependent DNA damage sensor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000228 nuclear chromosome;GO:0062128 MutSgamma complex", "go_biological_process": "GO:0006298 mismatch repair;GO:0007131 reciprocal meiotic recombination;GO:0051026 chiasma assembly", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q12175-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12180-1", "uniprot_id": "HAL9_YEAST", "mass": 117927.0, "length": 1030, "protein_name": "Halotolerance protein 9", "gene_name": "HAL9", "organism": "Yeast", "refseq_name": "Hal9p", "refseq_ac": "NP_014552", "gene_names_uniprotkb": "HAL9; O0938", "gene_names_refseq": "HAL9", "protein_names_uniprotkb": "Halotolerance protein 9", "protein_names_refseq": "Hal9p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL089C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "14562095;14562106;17330950;18407956;19779198;23749301;24374639;32597660;33481703;33491328;8533473;9169874;9559673", "class_list": "", "function": "Putative transcription factor involved in halotolerance., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1X9", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0009651 response to salt stress", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q12180-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12192-1", "uniprot_id": "RFM1_YEAST", "mass": 35195.0, "length": 310, "protein_name": "Repression factor of MSEs protein 1", "gene_name": "RFM1", "organism": "Yeast", "refseq_name": "Rfm1p", "refseq_ac": "NP_014922", "gene_names_uniprotkb": "RFM1", "gene_names_refseq": "RFM1", "protein_names_uniprotkb": "Repression factor of MSEs protein 1", "protein_names_refseq": "Rfm1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR279C)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "12612074;14562106;17563356;18407956;19779198;20702584;21126336;23749301;24374639;32597660;33481703;33491328;8896271;9169874", "class_list": "", "function": "Tethering factor required for histone deacetylase HST1-mediated repression. Probably involved in targeting HST1 to a subset of SUM1-regulated genes., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2X8", "ec_number_list": "", "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0000118 histone deacetylase complex", "go_biological_process": "GO:0030174 regulation of DNA-templated DNA replication initiation;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0000278 mitotic cell cycle;GO:0006357 regulation of transcription by RNA polymerase II;GO:0032298 positive regulation of DNA-templated DNA replication initiation", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q12192-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12199-1", "uniprot_id": "TIP41_YEAST", "mass": 41020.0, "length": 356, "protein_name": "Type 2A phosphatase activator TIP41", "gene_name": "TIP41", "organism": "Yeast", "refseq_name": "Tip41p", "refseq_ac": "NP_015365", "gene_names_uniprotkb": "TIP41; YP3085.04", "gene_names_refseq": "TIP41", "protein_names_uniprotkb": "Type 2A phosphatase activator TIP41; PP2A phosphatase activator TIP41; TAP42-interacting protein 1", "protein_names_refseq": "Tip41p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR040W)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "11741537;14504216;14562095;15470255;17563356;18407956;19779198;20702584;21126336;21177495;23749301;24374639;32597660;33229814;33481703;33491328;8972573;9169875", "class_list": "", "function": "Involved in negative regulation of the TOR signaling pathway in response to type of available nitrogen source. Indirectly activates the PP2A phosphatase SIT4 via interaction with its suppressor TAP42. This interaction is enhanced under nitrogen limitation conditions. Also has a role in regulation of NPR1 in response to nitrogen limitation., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "D6W449", "ec_number_list": "", "go_molecular_function": "GO:0072542 protein phosphatase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0031929 TOR signaling;GO:1904262 negative regulation of TORC1 signaling", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "Q12199-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12204-1", "uniprot_id": "YOR22_YEAST", "mass": 81769.0, "length": 715, "protein_name": "Probable phospholipase YOR022C, mitochondrial", "gene_name": "OR26.12", "organism": "Yeast", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "OR26.12", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable phospholipase YOR022C, mitochondrial; 3.1.1.-", "protein_names_refseq": "", "tax_id": 559292, "disease": "hereditary spastic paraplegia 28 (Disease Ontology:DOID:0110779); hereditary spastic paraplegia 54 (Disease Ontology:DOID:0110806); hereditary spastic paraplegia (Disease Ontology:DOID:2476)", "pathway": " (sce:YOR022C); (R-SCE-1483166); (R-SCE-1483226); (R-SCE-204005)", "pathway_count": 4, "publication_count": 6, "publication_id_list": "14562095;14562106;16823961;21177495;24374639;9169874", "class_list": "", "function": "Probable phospholipase that hydrolyzes phosphatidic acid., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W289", "ec_number_list": "2.3.1.-;3.1.1.-", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004620 phospholipase activity;GO:0008970 phospholipase A1 activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0016042 lipid catabolic process;GO:0006644 phospholipid metabolic process;GO:0032048 cardiolipin metabolic process;GO:0046337 phosphatidylethanolamine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q12204-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12205-1", "uniprot_id": "MNL2_YEAST", "mass": 96997.0, "length": 849, "protein_name": "Putative endoplasmic reticulum mannosidase MNL2", "gene_name": "MNL2", "organism": "Yeast", "refseq_name": "putative mannosidase MNL2", "refseq_ac": "NP_013158", "gene_names_uniprotkb": "MNL2; L2153", "gene_names_refseq": "MNL2", "protein_names_uniprotkb": "Putative endoplasmic reticulum mannosidase MNL2; 3.2.1.-; Mannosidase-like protein 2", "protein_names_refseq": "putative mannosidase MNL2", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR057W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562106;17322287;19795423;19823750;21971548;24374639;9169871", "class_list": "", "function": "Putative mannosidase involved in glycoprotein quality control since it is involved in the targeting of misfolded glycoproteins for ER-associated protein degradation (ERAD)., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VY59;Q7LGY1", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0036503 ERAD pathway", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q12205-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12209-1", "uniprot_id": "FRE8_YEAST", "mass": 78949.0, "length": 686, "protein_name": "Probable ferric reductase transmembrane component 8", "gene_name": "FRE8", "organism": "Yeast", "refseq_name": "putative ferric-chelate reductase", "refseq_ac": "NP_013148", "gene_names_uniprotkb": "FRE8; L2114", "gene_names_refseq": "FRE8", "protein_names_uniprotkb": "Probable ferric reductase transmembrane component 8; 1.16.1.7; Ferric-chelate reductase 8", "protein_names_refseq": "putative ferric-chelate reductase", "tax_id": 559292, "disease": "congenital hypothyroidism (Disease Ontology:DOID:0050328); primary bacterial infectious disease (Disease Ontology:DOID:0050338); renal fibrosis (Disease Ontology:DOID:0050855); X-linked chronic granulomatous disease (Disease Ontology:DOID:0070195); metabolic dysfunction-associated steatohepatitis (Disease Ontology:DOID:0080547); immunodeficiency 34 (Disease Ontology:DOID:0112000); thyroid dyshormonogenesis 6 (Disease Ontology:DOID:0112189); hypertension (Disease Ontology:DOID:10763); hypothyroidism (Disease Ontology:DOID:1459); cholera (Disease Ontology:DOID:1498); chronic granulomatous disease (Disease Ontology:DOID:3265); primary hyperaldosteronism (Disease Ontology:DOID:446); myocardial infarction (Disease Ontology:DOID:5844); pulmonary hypertension (Disease Ontology:DOID:6432); end stage renal disease (Disease Ontology:DOID:783); ulcerative colitis (Disease Ontology:DOID:8577); Crohn's disease (Disease Ontology:DOID:8778); steatotic liver disease (Disease Ontology:DOID:9452); obesity (Disease Ontology:DOID:9970)", "pathway": " (sce:YLR047C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14534306;16847258;19779198;24374639;33481703;33491328;9169871", "class_list": "", "function": "Required for the uptake of Fe(3+) ions. May participate in the transport of electrons from cytoplasm to an extracellular substrate (Fe(3+) ion) via FAD and heme intermediates (By similarity). Involved in iron homeostasis., [UniProtKB, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 3, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 19, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "D6VY49", "ec_number_list": "1.16.1.7", "go_molecular_function": "GO:0016722 oxidoreductase activity, acting on metal ions;GO:0000293 ferric-chelate reductase activity;GO:0140618 ferric-chelate reductase (NADH) activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0030003 intracellular monoatomic cation homeostasis;GO:0033212 iron import into cell", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q12209-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12215-1", "uniprot_id": "WSC3_YEAST", "mass": 58230.0, "length": 556, "protein_name": "Cell wall integrity and stress response component 3", "gene_name": "WSC3", "organism": "Yeast", "refseq_name": "Wsc3p", "refseq_ac": "NP_014536", "gene_names_uniprotkb": "WSC3; HRE556", "gene_names_refseq": "WSC3", "protein_names_uniprotkb": "Cell wall integrity and stress response component 3", "protein_names_refseq": "Wsc3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL105C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "15905473;16847258;19779198;23749301;24374639;33491328;7502582;9169874", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6W1W1;Q2VQX5", "ec_number_list": "", "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0000324 fungal-type vacuole;GO:0043332 mating projection tip", "go_biological_process": "GO:0007266 Rho protein signal transduction;GO:0009408 response to heat;GO:0000425 pexophagy;GO:0071555 cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q12215-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12218-1", "uniprot_id": "TIR4_YEAST", "mass": 47849.0, "length": 487, "protein_name": "Cell wall protein TIR4", "gene_name": "TIR4", "organism": "Yeast", "refseq_name": "Tir4p", "refseq_ac": "NP_014652", "gene_names_uniprotkb": "TIR4; UNB487", "gene_names_refseq": "TIR4", "protein_names_uniprotkb": "Cell wall protein TIR4; TIP1-related protein 4", "protein_names_refseq": "Tir4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR009W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10383953;11292809;16086015;24374639;8896276;9169874;9613572", "class_list": "", "function": "Component of the cell wall. Required for anaerobic growth., [UniProtKB, PubMed]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6W276", "ec_number_list": "", "go_molecular_function": "GO:0005199 structural constituent of cell wall", "go_cellular_component": "GO:0071944 cell periphery;GO:0000324 fungal-type vacuole;GO:0009277 fungal-type cell wall;GO:0098552 side of membrane", "go_biological_process": "GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q12218-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12222-1", "uniprot_id": "YGK3_YEAST", "mass": 43206.0, "length": 375, "protein_name": "Glycogen synthase kinase-3 homolog YGK3", "gene_name": "YGK3", "organism": "Yeast", "refseq_name": "serine/threonine protein kinase YGK3", "refseq_ac": "NP_014513", "gene_names_uniprotkb": "YGK3", "gene_names_refseq": "YGK3", "protein_names_uniprotkb": "Glycogen synthase kinase-3 homolog YGK3; 2.7.11.1", "protein_names_refseq": "serine/threonine protein kinase YGK3", "tax_id": 559292, "disease": "developmental and epileptic encephalopathy 2 (Disease Ontology:DOID:0080467); developmental and epileptic encephalopathy (Disease Ontology:DOID:0112202); intellectual disability (Disease Ontology:DOID:1059); Rett syndrome (Disease Ontology:DOID:1206)", "pathway": " (sce:YOL128C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10958669;12529445;12704202;17287358;18407956;20489023;20702584;23749301;24374639;32597660;33491328;8896265;9169874", "class_list": "", "function": "Required for heat stress-instigated phosphorylation of BCY1 which is involved in cell wall integrity signaling. Regulates activity of MSN2, a transcription factor that binds to the stress-response element (STRE). Probably promotes formation of a complex between MSN2 and DNA. Regulates the stability of ROG1., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1U0", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q12222-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12232-1", "uniprot_id": "SLP1_YEAST", "mass": 67452.0, "length": 587, "protein_name": "Uncharacterized protein SLP1", "gene_name": "SLP1", "organism": "Yeast", "refseq_name": "Slp1p", "refseq_ac": "NP_014797", "gene_names_uniprotkb": "SLP1; O3545", "gene_names_refseq": "SLP1", "protein_names_uniprotkb": "Uncharacterized protein SLP1; SUN-like protein 1", "protein_names_refseq": "Slp1p", "tax_id": 559292, "disease": "osteogenesis imperfecta type 5 (Disease Ontology:DOID:0110344)", "pathway": " (sce:YOR154W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "11935221;14562106;16923827;19325107;23275891;24374639;9046089;9169874", "class_list": "", "function": "May be involved in membrane protein folding (PubMed:19325107). Required for localization of MPS3 to the nuclear envelope (PubMed:23275891)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 6, "predicted_n_glycosites": 6, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "D6W2L1", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0034975 protein folding in endoplasmic reticulum", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q12232-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12233-1", "uniprot_id": "ATPN_YEAST", "mass": 12921.0, "length": 115, "protein_name": "ATP synthase subunit g, mitochondrial", "gene_name": "ATP20", "organism": "Yeast", "refseq_name": "F1F0 ATP synthase subunit g", "refseq_ac": "NP_015345", "gene_names_uniprotkb": "ATP20; YP9531.14", "gene_names_refseq": "ATP20", "protein_names_uniprotkb": "ATP synthase subunit g, mitochondrial; ATPase subunit g", "protein_names_refseq": "F1F0 ATP synthase subunit g", "tax_id": 559292, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652)", "pathway": " (sce:YPR020W); (R-SCE-9837999)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "17322287;17761666;24374639;9169875;9857174", "class_list": "", "function": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W430", "ec_number_list": "", "go_molecular_function": "GO:0015078 proton transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0045259 proton-transporting ATP synthase complex", "go_biological_process": "GO:0042407 cristae formation;GO:0015986 proton motive force-driven ATP synthesis;GO:0065003 protein-containing complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q12233-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12235-1", "uniprot_id": "YCT1_YEAST", "mass": 58905.0, "length": 531, "protein_name": "High affinity cysteine transporter", "gene_name": "YCT1", "organism": "Yeast", "refseq_name": "Yct1p", "refseq_ac": "NP_013045", "gene_names_uniprotkb": "YCT1; L0578", "gene_names_refseq": "YCT1", "protein_names_uniprotkb": "High affinity cysteine transporter", "protein_names_refseq": "Yct1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLL055W)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "11113969;14562095;16847258;17322287;17435223;18407956;18794233;19779198;20233714;20702584;21177495;24374639;33481703;33491328;9169871", "class_list": "", "function": "High affinity cysteine-specific transporter. Major contributor to cysteine transport when cysteine, at low concentrations, is provided as the sole sulfur source., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VXV3", "ec_number_list": "", "go_molecular_function": "GO:0033229 cysteine transmembrane transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0042883 cysteine transport", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q12235-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12283-1", "uniprot_id": "FABD_YEAST", "mass": 40707.0, "length": 360, "protein_name": "Malonyl CoA-acyl carrier protein transacylase, mitochondrial", "gene_name": "MCT1", "organism": "Yeast", "refseq_name": "[acyl-carrier-protein] S-malonyltransferase", "refseq_ac": "NP_014864", "gene_names_uniprotkb": "MCT1; YOR50-11", "gene_names_refseq": "MCT1", "protein_names_uniprotkb": "Malonyl CoA-acyl carrier protein transacylase, mitochondrial; 2.3.1.39; MCT; Malonyl-CoA:ACP transferase", "protein_names_refseq": "[acyl-carrier-protein] S-malonyltransferase", "tax_id": 559292, "disease": "optic atrophy (Disease Ontology:DOID:5723)", "pathway": " (sce:YOR221C); (R-SCE-77289)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "14562095;14562106;16823961;24374639;33481703;8840505;9169874;9388293", "class_list": "", "function": "Involved in biosynthesis of fatty acids in mitochondria., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2S6", "ec_number_list": "2.3.1.38;2.3.1.39;3.1.2.14;4.2.1.59;2.3.1.86;1.3.1.9", "go_molecular_function": "GO:0004314 [acyl-carrier-protein] S-malonyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0006633 fatty acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q12283-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12289-1", "uniprot_id": "CRC1_YEAST", "mass": 34754.0, "length": 327, "protein_name": "Mitochondrial carnitine carrier", "gene_name": "CRC1", "organism": "Yeast", "refseq_name": "carnitine:acyl carnitine antiporter", "refseq_ac": "NP_014743", "gene_names_uniprotkb": "CRC1; YOR3193C", "gene_names_refseq": "CRC1", "protein_names_uniprotkb": "Mitochondrial carnitine carrier", "protein_names_refseq": "carnitine:acyl carnitine antiporter", "tax_id": 559292, "disease": "carnitine-acylcarnitine translocase deficiency (Disease Ontology:DOID:0111585); lipid metabolism disorder (Disease Ontology:DOID:3146)", "pathway": " (sce:YOR100C); (R-SCE-200425)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "10545096;10622748;17322287;24374639;9169874;9200815", "class_list": "", "function": "Transports carnitine, acetylcarnitine, propionylcarnitine and to a much lower extent medium- and long-chain acylcarnitines., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2G1", "ec_number_list": "", "go_molecular_function": "GO:0005476 carnitine:O-acyl-L-carnitine antiporter activity;GO:0015227 O-acyl-L-carnitine transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005740 mitochondrial envelope;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0006839 mitochondrial transport;GO:1902603 carnitine transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q12289-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12296-1", "uniprot_id": "MAM3_YEAST", "mass": 77712.0, "length": 706, "protein_name": "Protein MAM3", "gene_name": "MAM3", "organism": "Yeast", "refseq_name": "Mam3p", "refseq_ac": "NP_014581", "gene_names_uniprotkb": "MAM3", "gene_names_refseq": "MAM3", "protein_names_uniprotkb": "Protein MAM3", "protein_names_refseq": "Mam3p", "tax_id": 559292, "disease": "renal hypomagnesemia 6 (Disease Ontology:DOID:0060884); Jalili syndrome (Disease Ontology:DOID:0111404); schizophrenia (Disease Ontology:DOID:5419)", "pathway": " (sce:YOL060C)", "pathway_count": 1, "publication_count": 21, "publication_id_list": "14562095;14562106;15498024;16847258;17287358;17322287;17563356;18407956;19684113;19779198;19795423;19823750;21177495;23749301;24374639;30516470;32597660;33481703;33491328;8789261;9169874", "class_list": "", "function": "Involved in metal homeostasis and more specifically in manganese sensitivity., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 48, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W207", "ec_number_list": "", "go_molecular_function": "GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0007005 mitochondrion organization;GO:0010961 intracellular magnesium ion homeostasis;GO:0030026 intracellular manganese ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "Q12296-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12308-1", "uniprot_id": "TFC8_YEAST", "mass": 67683.0, "length": 588, "protein_name": "Transcription factor tau 60 kDa subunit", "gene_name": "TFC8", "organism": "Yeast", "refseq_name": "transcription factor TFIIIC subunit TFC8", "refseq_ac": "NP_015318", "gene_names_uniprotkb": "TFC8", "gene_names_refseq": "TFC8", "protein_names_uniprotkb": "Transcription factor tau 60 kDa subunit; TFIIIC 60 kDa subunit; Transcription factor C subunit 8", "protein_names_refseq": "transcription factor TFIIIC subunit TFC8", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL007C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10567530;14562095;14562106;16115780;17052456;22814378;24374639;9169875", "class_list": "", "function": "TFIIIC mediates tRNA and 5S RNA gene activation by binding to intragenic promoter elements. Upstream of the transcription start site, TFIIIC assembles the initiation complex TFIIIB-TFIIIC-tDNA, which is sufficient for RNA polymerase III recruitment and function. Part of the tauB domain of TFIIIC that binds boxB DNA promoter sites of tRNA and similar genes. Plays a role in TFIIB assembly through its interaction with SPT15/TBP. Essential for cell viability., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W405", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0000127 transcription factor TFIIIC complex;GO:0005634 nucleus", "go_biological_process": "GO:0042791 5S class rRNA transcription by RNA polymerase III;GO:0006383 transcription by RNA polymerase III;GO:0006384 transcription initiation at RNA polymerase III promoter", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q12308-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12310-1", "uniprot_id": "PRR2_YEAST", "mass": 78939.0, "length": 699, "protein_name": "Serine/threonine-protein kinase PRR2", "gene_name": "PRR2", "organism": "Yeast", "refseq_name": "serine/threonine protein kinase PRR2", "refseq_ac": "NP_010067", "gene_names_uniprotkb": "PRR2; D1014", "gene_names_refseq": "PRR2", "protein_names_uniprotkb": "Serine/threonine-protein kinase PRR2; 2.7.11.1; Pheromone response regulator 2", "protein_names_refseq": "serine/threonine protein kinase PRR2", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL214C); (R-SCE-176187); (R-SCE-5693616); (R-SCE-69601)", "pathway_count": 4, "publication_count": 8, "publication_id_list": "10940301;11062466;11337509;16319894;20489023;24374639;9046097;9169867", "class_list": "", "function": "Protein kinase that functions as a regulator in the pheromone-induced mating pathway downstream of mitogen-activated protein kinase (MAPK) FUS3. Diminishes transcriptional induction of genes in response to pheromone signaling., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRE0", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;3.1.3.48;2.7.11.13;3.6.4.-;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0019236 response to pheromone;GO:0031138 negative regulation of conjugation with cellular fusion", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q12310-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12320-1", "uniprot_id": "GLO4_YEAST", "mass": 32339.0, "length": 285, "protein_name": "Hydroxyacylglutathione hydrolase, mitochondrial", "gene_name": "GLO4", "organism": "Yeast", "refseq_name": "hydroxyacylglutathione hydrolase GLO4", "refseq_ac": "NP_014683", "gene_names_uniprotkb": "GLO4; GER1; O2758; OR26.33", "gene_names_refseq": "GLO4", "protein_names_uniprotkb": "Hydroxyacylglutathione hydrolase, mitochondrial; 3.1.2.6; Glx II; Glyoxalase II", "protein_names_refseq": "hydroxyacylglutathione hydrolase GLO4", "tax_id": 559292, "disease": "paroxysmal nonkinesigenic dyskinesia 1 (Disease Ontology:DOID:0090049)", "pathway": " (sce:YOR040W); (R-SCE-70268)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "10600466;17322287;24374639;33491328;9169874;9261170", "class_list": "", "function": "Thiolesterase that catalyzes the hydrolysis of S-D-lactoylglutathione to form glutathione and D-lactic acid. Involved in the metabolism of methylglyoxal, a toxic compound for yeast proliferation, by converting methylglyoxal to lactate via S-D-lactoylglutathione by sequential enzyme reactions catalyzed by glyoxalase I and glyoxalase II., [UniProtKB, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2A7", "ec_number_list": "3.1.2.6", "go_molecular_function": "GO:0004416 hydroxyacylglutathione hydrolase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q12320-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12326-1", "uniprot_id": "PMG3_YEAST", "mass": 34863.0, "length": 303, "protein_name": "Phosphoglycerate mutase 3", "gene_name": "GPM3", "organism": "Yeast", "refseq_name": "phosphoglycerate mutase family protein GPM3", "refseq_ac": "NP_014585", "gene_names_uniprotkb": "GPM3; O1236", "gene_names_refseq": "GPM3", "protein_names_uniprotkb": "Phosphoglycerate mutase 3; 5.4.2.11; BPG-dependent PGAM 3; MPGM 3; PGAM 3; Phosphoglyceromutase 3", "protein_names_refseq": "phosphoglycerate mutase family protein GPM3", "tax_id": 559292, "disease": "familial erythrocytosis 8 (Disease Ontology:DOID:0111630)", "pathway": " (sce:YOL056W); (R-SCE-70171); (R-SCE-70263)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "14562106;24374639;33491328;8789261;9169874;9544241", "class_list": "", "function": "Could be non-functional., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W211", "ec_number_list": "5.4.2.11", "go_molecular_function": "GO:0004619 phosphoglycerate mutase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0061621 canonical glycolysis", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q12326-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12345-1", "uniprot_id": "IES3_YEAST", "mass": 28243.0, "length": 250, "protein_name": "Ino eighty subunit 3", "gene_name": "IES3", "organism": "Yeast", "refseq_name": "Ies3p", "refseq_ac": "NP_013153", "gene_names_uniprotkb": "IES3; L2131", "gene_names_refseq": "IES3", "protein_names_uniprotkb": "Ino eighty subunit 3", "protein_names_refseq": "Ies3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR052W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "12887900;14562095;14562106;18407956;19779198;24374639;32597660;33481703;33491328;9169871", "class_list": "", "function": "Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin-remodeling complex., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VY54", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0031011 Ino80 complex;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0031509 subtelomeric heterochromatin formation;GO:0006281 DNA repair;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q12345-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12348-1", "uniprot_id": "CSN10_YEAST", "mass": 76388.0, "length": 645, "protein_name": "COP9 signalosome complex subunit 10", "gene_name": "RRI2", "organism": "Yeast", "refseq_name": "Rri2p", "refseq_ac": "NP_014524", "gene_names_uniprotkb": "RRI2; CSN10", "gene_names_refseq": "CSN10; RRI2", "protein_names_uniprotkb": "COP9 signalosome complex subunit 10", "protein_names_refseq": "Rri2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL117W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "11805826;12186635;12446563;12672462;14562095;14562106;19779198;24374639;33491328;7502582;9169874", "class_list": "", "function": "Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes. The CSN complex is involved in the regulation of the mating pheromone response., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1V0", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0008180 COP9 signalosome", "go_biological_process": "GO:0000338 protein deneddylation;GO:0071444 cellular response to pheromone;GO:2000434 regulation of protein neddylation;GO:0000747 conjugation with cellular fusion;GO:0000754 adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q12348-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12354-1", "uniprot_id": "APTH1_YEAST", "mass": 24700.0, "length": 227, "protein_name": "Acyl-protein thioesterase 1", "gene_name": "L2955", "organism": "Yeast", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "L2955", "gene_names_refseq": "", "protein_names_uniprotkb": "Acyl-protein thioesterase 1; 3.1.2.-; 3.1.2.22; Palmitoyl-protein hydrolase", "protein_names_refseq": "", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR118C); (R-SCE-203615); (R-SCE-9648002)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "12080046;14562095;14562106;14645503;17322287;17563356;19779198;24374639;33491328;9090053;9169871", "class_list": "", "function": "Hydrolyzes fatty acids from S-acylated cysteine residues in proteins with a strong preference for palmitoylated G-alpha proteins over other acyl substrates. Mediates the deacylation of G-alpha proteins such as GPA1 in vivo, but has weak or no activity toward palmitoylated Ras proteins. Has weak lysophospholipase activity in vitro; however such activity may not exist in vivo., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYB6", "ec_number_list": "1.6.2.4;3.1.2.22;3.1.2.-", "go_molecular_function": "GO:0052689 carboxylic ester hydrolase activity;GO:0008474 palmitoyl-(protein) hydrolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0035601 protein deacylation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q12354-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12359-1", "uniprot_id": "ATO3_YEAST", "mass": 30028.0, "length": 275, "protein_name": "Ammonia transport outward protein 3", "gene_name": "ATO3", "organism": "Yeast", "refseq_name": "putative ammonium permease ATO3", "refseq_ac": "NP_010672", "gene_names_uniprotkb": "ATO3; D9481.20; D9509.4", "gene_names_refseq": "ATO3", "protein_names_uniprotkb": "Ammonia transport outward protein 3", "protein_names_refseq": "putative ammonium permease ATO3", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR384C)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "11875433;12429834;12966084;15743812;16847258;17395151;17761666;18407956;19795423;19823750;20702584;22218487;23749301;24374639;32597660;33481703;33491328;9169867", "class_list": "", "function": "Transporter protein required for ammonia export. Induced in rho(0) cells, probably to eliminate the excess ammonia that arises because of a potential defect in ammonia assimilation in those cells., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VT18", "ec_number_list": "", "go_molecular_function": "GO:0008519 ammonium channel activity;GO:0015123 acetate transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005886 plasma membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0006811 monoatomic ion transport;GO:0055085 transmembrane transport;GO:0072488 ammonium transmembrane transport;GO:0019740 nitrogen utilization", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "Q12359-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12375-1", "uniprot_id": "ORT1_YEAST", "mass": 31520.0, "length": 292, "protein_name": "Mitochondrial ornithine transporter 1", "gene_name": "ORT1", "organism": "Yeast", "refseq_name": "Ort1p", "refseq_ac": "NP_014773", "gene_names_uniprotkb": "ORT1; ARG11; O3299; YOR3299C", "gene_names_refseq": "ARG11; ORT1", "protein_names_uniprotkb": "Mitochondrial ornithine transporter 1", "protein_names_refseq": "Ort1p", "tax_id": 559292, "disease": "ornithine translocase deficiency (Disease Ontology:DOID:0050720); amino acid metabolic disorder (Disease Ontology:DOID:9252); citrullinemia (Disease Ontology:DOID:9273)", "pathway": " (sce:YOR130C); (R-SCE-70635)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "14562095;14562106;24374639;33491328;8798783;8904341;9169874;9200815;9237680", "class_list": "", "function": "Required for arginine biosynthesis. Transports ornithine synthesized from glutamate in the mitochondrial matrix to the cytosol, where it is converted to arginine., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2I8;Q92273", "ec_number_list": "", "go_molecular_function": "GO:0000064 L-ornithine transmembrane transporter activity;GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005740 mitochondrial envelope;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006526 L-arginine biosynthetic process;GO:1990575 mitochondrial L-ornithine transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q12375-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12378-1", "uniprot_id": "RTR2_YEAST", "mass": 22541.0, "length": 196, "protein_name": "RNA polymerase II subunit B1 CTD phosphatase RTR2", "gene_name": "RTR2", "organism": "Yeast", "refseq_name": "putative protein-serine/threonine phosphatase", "refseq_ac": "NP_010351", "gene_names_uniprotkb": "RTR2; D4261", "gene_names_refseq": "RTR2", "protein_names_uniprotkb": "RNA polymerase II subunit B1 CTD phosphatase RTR2; 3.1.3.16; RNA polymerase II-associated protein 2 homolog RTR2; Regulator of transcription 2", "protein_names_refseq": "putative protein-serine/threonine phosphatase", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR066C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562095;14562106;18408053;24374639;33491328;8789263;9169867", "class_list": "", "function": "Probable RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase that regulates RNA polymerase II transcription. May have functional redundancy with RTR1., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS52", "ec_number_list": "3.1.3.16;3.1.3.43;3.1.3.48", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0043175 RNA polymerase core enzyme binding;GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q12378-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12387-1", "uniprot_id": "NAA25_YEAST", "mass": 92809.0, "length": 796, "protein_name": "N-terminal acetyltransferase B complex subunit MDM20", "gene_name": "MDM20", "organism": "Yeast", "refseq_name": "Mdm20p", "refseq_ac": "NP_014566", "gene_names_uniprotkb": "MDM20; DEC1", "gene_names_refseq": "DEC1; MDM20; NAA25", "protein_names_uniprotkb": "N-terminal acetyltransferase B complex subunit MDM20; Dislikes extra CIN8 protein 1; Mitochondrial distribution and morphology protein 20; NatB complex subunit MDM20", "protein_names_refseq": "Mdm20p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL076W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "12783868;12808144;14562095;14562106;17322287;19795423;19823750;22814378;24374639;9105043;9169874;9178509", "class_list": "", "function": "Non-catalytic subunit of the NatB N-terminal acetyltransferase, which catalyzes acetylation of the amino-terminal methionine residues of all proteins beginning with Met-Asp or Met-Glu and of some proteins beginning with Met-Asn or Met-Met. NatB acetylates TPM1 protein and regulates tropomyocin-actin interactions. MDM20 is required for mitochondrial inheritance during budding and together with TPM1, is essential for the integrity and assembly of actin cables. Genetically interacts with CIN8., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1Z2", "ec_number_list": "", "go_molecular_function": "GO:0010698 acetyltransferase activator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0031416 NatB complex", "go_biological_process": "GO:0032956 regulation of actin cytoskeleton organization;GO:0007010 cytoskeleton organization;GO:0017196 N-terminal peptidyl-methionine acetylation;GO:0000001 mitochondrion inheritance", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q12387-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12390-1", "uniprot_id": "GST2_YEAST", "mass": 26340.0, "length": 233, "protein_name": "Glutathione S-transferase 2", "gene_name": "GTT2", "organism": "Yeast", "refseq_name": "glutathione transferase GTT2", "refseq_ac": "NP_013040", "gene_names_uniprotkb": "GTT2; L0560", "gene_names_refseq": "GTT2", "protein_names_uniprotkb": "Glutathione S-transferase 2; 2.5.1.18; GST-II", "protein_names_refseq": "glutathione transferase GTT2", "tax_id": 559292, "disease": "orofacial cleft (Disease Ontology:DOID:0050567); inflammatory bowel disease (Disease Ontology:DOID:0050589); alcohol dependence (Disease Ontology:DOID:0050741); diffuse large B-cell lymphoma (Disease Ontology:DOID:0050745); colorectal adenocarcinoma (Disease Ontology:DOID:0050861); medulloblastoma (Disease Ontology:DOID:0050902); myelodysplastic syndrome (Disease Ontology:DOID:0050908); pre-malignant neoplasm (Disease Ontology:DOID:0060071); acute promyelocytic leukemia (Disease Ontology:DOID:0060318); drug allergy (Disease Ontology:DOID:0060500); alcohol-associated liver disease (Disease Ontology:DOID:0070658); mucositis (Disease Ontology:DOID:0080178); colorectal carcinoma (Disease Ontology:DOID:0080199); COVID-19 (Disease Ontology:DOID:0080600); venous insufficiency (Disease Ontology:DOID:10128); osteonecrosis (Disease Ontology:DOID:10159); prostate cancer (Disease Ontology:DOID:10283); lymphoid leukemia (Disease Ontology:DOID:1037); Hirschsprung's disease (Disease Ontology:DOID:10487); stomach cancer (Disease Ontology:DOID:10534); Charcot-Marie-Tooth disease (Disease Ontology:DOID:10595); Alzheimer's disease (Disease Ontology:DOID:10652); primary open angle glaucoma (Disease Ontology:DOID:1070); hypertension (Disease Ontology:DOID:10763); Kuhnt-Junius degeneration (Disease Ontology:DOID:10873); hypospadias (Disease Ontology:DOID:10892); sickle cell anemia (Disease Ontology:DOID:10923); urinary bladder cancer (Disease Ontology:DOID:11054); bronchopulmonary dysplasia (Disease Ontology:DOID:11650); head and neck cancer (Disease Ontology:DOID:11934); optic neuritis (Disease Ontology:DOID:1210); beta thalassemia (Disease Ontology:DOID:12241); neutropenia (Disease Ontology:DOID:1227); aplastic anemia (Disease Ontology:DOID:12449); cardiovascular system disease (Disease Ontology:DOID:1287); lung cancer (Disease Ontology:DOID:1324); Fanconi anemia (Disease Ontology:DOID:13636); exfoliation syndrome (Disease Ontology:DOID:13641); Parkinson's disease (Disease Ontology:DOID:14330); aggressive periodontitis (Disease Ontology:DOID:1474); cystic fibrosis (Disease Ontology:DOID:1485); acute chest syndrome (Disease Ontology:DOID:1584); breast cancer (Disease Ontology:DOID:1612); cancer (Disease Ontology:DOID:162); congenital heart disease (Disease Ontology:DOID:1682); ovary epithelial cancer (Disease Ontology:DOID:2152); motor neuron disease (Disease Ontology:DOID:231); colon adenocarcinoma (Disease Ontology:DOID:234); anemia (Disease Ontology:DOID:2355); multiple sclerosis (Disease Ontology:DOID:2377); transitional cell carcinoma (Disease Ontology:DOID:2671); asthma (Disease Ontology:DOID:2841); cervix carcinoma (Disease Ontology:DOID:2893); pulmonary tuberculosis (Disease Ontology:DOID:2957); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); atopic dermatitis (Disease Ontology:DOID:3310); coronary artery disease (Disease Ontology:DOID:3393); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); Lynch syndrome (Disease Ontology:DOID:3883); pancreatic adenocarcinoma (Disease Ontology:DOID:4074); liver disease (Disease Ontology:DOID:409); cervical cancer (Disease Ontology:DOID:4362); renal cell carcinoma (Disease Ontology:DOID:4450); esophagus adenocarcinoma (Disease Ontology:DOID:4914); esophageal cancer (Disease Ontology:DOID:5041); liver cirrhosis (Disease Ontology:DOID:5082); peripheral nervous system disease (Disease Ontology:DOID:574); oral submucous fibrosis (Disease Ontology:DOID:5773); leukopenia (Disease Ontology:DOID:615); systemic juvenile rheumatoid arthritis (Disease Ontology:DOID:676); hepatocellular carcinoma (Disease Ontology:DOID:684); rheumatoid arthritis (Disease Ontology:DOID:7148); end stage renal disease (Disease Ontology:DOID:783); cataract (Disease Ontology:DOID:83); lung disease (Disease Ontology:DOID:850); Hodgkin's lymphoma (Disease Ontology:DOID:8567); infectious mononucleosis (Disease Ontology:DOID:8568); ulcerative colitis (Disease Ontology:DOID:8577); oral cavity cancer (Disease Ontology:DOID:8618); myeloid leukemia (Disease Ontology:DOID:8692); Crohn's disease (Disease Ontology:DOID:8778); skin melanoma (Disease Ontology:DOID:8923); diabetic retinopathy (Disease Ontology:DOID:8947); acute myeloid leukemia (Disease Ontology:DOID:9119); colorectal cancer (Disease Ontology:DOID:9256); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352); multiple myeloma (Disease Ontology:DOID:9538); oral mucosa leukoplakia (Disease Ontology:DOID:9655); senile cataract (Disease Ontology:DOID:9669); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (sce:YLL060C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "17322287;19851333;24374639;9169871;9792709", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 91, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXU9", "ec_number_list": "1.11.1.9;2.5.1.18;1.8.5.1", "go_molecular_function": "GO:0004364 glutathione transferase activity;GO:0043295 glutathione binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0006749 glutathione metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q12390-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12403-1", "uniprot_id": "ERP3_YEAST", "mass": 26511.0, "length": 225, "protein_name": "Protein ERP3", "gene_name": "ERP3", "organism": "Yeast", "refseq_name": "Erp3p", "refseq_ac": "NP_010266", "gene_names_uniprotkb": "ERP3; D2850", "gene_names_refseq": "ERP3", "protein_names_uniprotkb": "Protein ERP3", "protein_names_refseq": "Erp3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL018C); (R-SCE-6807878); (R-SCE-6811434)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "10359606;14562106;24374639;9169867", "class_list": "", "function": "Involved in vesicular protein trafficking., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRX2", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0016020 membrane;GO:0030134 COPII-coated ER to Golgi transport vesicle;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0016192 vesicle-mediated transport;GO:0007030 Golgi organization;GO:0006621 protein retention in ER lumen", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q12403-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12405-1", "uniprot_id": "LPX1_YEAST", "mass": 43727.0, "length": 387, "protein_name": "Peroxisomal membrane protein LPX1", "gene_name": "LPX1", "organism": "Yeast", "refseq_name": "triglyceride lipase", "refseq_ac": "NP_014727", "gene_names_uniprotkb": "LPX1; YOR3120W", "gene_names_refseq": "LPX1", "protein_names_uniprotkb": "Peroxisomal membrane protein LPX1; 3.1.1.-; Lipase of peroxisomes protein 1", "protein_names_refseq": "triglyceride lipase", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR084W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "12135984;14512416;14562106;17322287;18199283;19235764;19684113;24374639;9169874;9200815", "class_list": "", "function": "Has acyl esterase, lipase and phospholipase A activity., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2E6", "ec_number_list": "", "go_molecular_function": "GO:0004806 triacylglycerol lipase activity", "go_cellular_component": "GO:0005782 peroxisomal matrix", "go_biological_process": "GO:0019433 triglyceride catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q12405-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12415-1", "uniprot_id": "TFC7_YEAST", "mass": 49146.0, "length": 435, "protein_name": "Transcription factor tau 55 kDa subunit", "gene_name": "TFC7", "organism": "Yeast", "refseq_name": "transcription factor TFIIIC subunit TFC7", "refseq_ac": "NP_014753", "gene_names_uniprotkb": "TFC7; O3234; YOR3234w", "gene_names_refseq": "TFC7", "protein_names_uniprotkb": "Transcription factor tau 55 kDa subunit; TFIIIC 55 kDa subunit; Transcription factor C subunit 7", "protein_names_refseq": "transcription factor TFIIIC subunit TFC7", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR110W)", "pathway_count": 1, "publication_count": 21, "publication_id_list": "14562095;14562106;15665377;17322287;17330950;17563356;18407956;19779198;19795423;19823750;21126336;22814378;23749301;24374639;32597660;33481703;33491328;8904341;9169874;9200815;9584160", "class_list": "", "function": "TFIIIC mediates tRNA and 5S RNA gene activation by binding to intragenic promoter elements. Upstream of the transcription start site, TFIIIC assembles the initiation complex TFIIIB-TFIIIC-tDNA, which is sufficient for RNA polymerase III recruitment and function. Part of the tauA domain of TFIIIC that binds boxA DNA promoter sites of tRNA and similar genes., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2G9;Q07347;Q6B220", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0016791 phosphatase activity", "go_cellular_component": "GO:0000127 transcription factor TFIIIC complex;GO:0005634 nucleus", "go_biological_process": "GO:0042791 5S class rRNA transcription by RNA polymerase III;GO:0006383 transcription by RNA polymerase III;GO:0006384 transcription initiation at RNA polymerase III promoter", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "Q12415-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12420-1", "uniprot_id": "SNU66_YEAST", "mass": 66430.0, "length": 587, "protein_name": "66 kDa U4/U6.U5 small nuclear ribonucleoprotein component", "gene_name": "SNU66", "organism": "Yeast", "refseq_name": "U4/U6-U5 snRNP complex subunit SNU66", "refseq_ac": "NP_014953", "gene_names_uniprotkb": "SNU66; 05667", "gene_names_refseq": "SNU66", "protein_names_uniprotkb": "66 kDa U4/U6.U5 small nuclear ribonucleoprotein component", "protein_names_refseq": "U4/U6-U5 snRNP complex subunit SNU66", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR308C)", "pathway_count": 1, "publication_count": 26, "publication_id_list": "10377396;10449419;11290703;11804584;14562095;15620657;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22218487;22814378;23749301;24374639;32597660;33481703;33491328;8896266;9153758;9169874", "class_list": "", "function": "Component of the U4/U6.U5 tri-snRNP particle, one of the building blocks of the spliceosome. Required for pre-mRNA splicing., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 19, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W308", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005681 spliceosomal complex;GO:0046540 U4/U6 x U5 tri-snRNP complex", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0000481 maturation of 5S rRNA;GO:0045292 mRNA cis splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 2.7, "record_id": "Q12420-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12427-1", "uniprot_id": "STB3_YEAST", "mass": 56264.0, "length": 513, "protein_name": "Protein STB3", "gene_name": "STB3", "organism": "Yeast", "refseq_name": "Stb3p", "refseq_ac": "NP_010453", "gene_names_uniprotkb": "STB3; YD9489.04c", "gene_names_refseq": "STB3", "protein_names_uniprotkb": "Protein STB3; SIN3-binding protein 3", "protein_names_refseq": "Stb3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR169C)", "pathway_count": 1, "publication_count": 24, "publication_id_list": "14562095;14562106;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22218487;23749301;24374639;32597660;33229814;33481703;33491328;33502312;34965436;9169867;9393435", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 21, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 21, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 21, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 33, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 21, "binding_glycan_count": 0, "secondary_ac_list": "D6VSE9", "ec_number_list": "", "go_molecular_function": "GO:0000976 transcription cis-regulatory region binding;GO:0043565 sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0071333 cellular response to glucose stimulus", "synthesized_glycan_count": 0, "hit_score": 4.7, "record_id": "Q12427-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12431-1", "uniprot_id": "EMC6_YEAST", "mass": 12404.0, "length": 108, "protein_name": "ER membrane protein complex subunit 6", "gene_name": "EMC6", "organism": "Yeast", "refseq_name": "Emc6p", "refseq_ac": "NP_013087", "gene_names_uniprotkb": "EMC6; L1321", "gene_names_refseq": "EMC6", "protein_names_uniprotkb": "ER membrane protein complex subunit 6", "protein_names_refseq": "Emc6p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLL014W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562095;17322287;19325107;24374639;29809151;8810043;9046100;9169871", "class_list": "", "function": "Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins (PubMed:29809151). Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues (PubMed:29809151). Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices (PubMed:29809151). It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes. By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins (By similarity)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXY8", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0072546 EMC complex;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0015914 phospholipid transport;GO:0006644 phospholipid metabolic process;GO:0034975 protein folding in endoplasmic reticulum;GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q12431-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12433-1", "uniprot_id": "AHC1_YEAST", "mass": 63869.0, "length": 566, "protein_name": "Protein AHC1", "gene_name": "AHC1", "organism": "Yeast", "refseq_name": "Ahc1p", "refseq_ac": "NP_014666", "gene_names_uniprotkb": "AHC1; OR26.13", "gene_names_refseq": "AHC1", "protein_names_uniprotkb": "Protein AHC1; ADA HAT complex component 1", "protein_names_refseq": "Ahc1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR023C)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "10026213;10490601;11313364;14562095;14562106;17287358;18407956;19779198;20702584;21734642;23749301;24374639;30516470;32597660;33481703;33491328;9169874;9224714", "class_list": "", "function": "Component of the ADA histone acetyltransferase complex, which preferentially acetylates nucleosomal histones H3 (to form H3K14ac and H3K18ac) and H2B. AHC1 is required for the overall structural integrity of the ADA complex., [UniProtKB, PubMed, PubMed]; Functions as a component of the transcription regulatory histone acetylation (HAT) complex ADA. ADA preferentially acetylates nucleosomal histones H3 (at 'Lys-14' and 'Lys-18') and H2B. AHC1 is required for the overall structural integrity of the ADA complex., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W290", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0140671 ADA complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:1990414 replication-born double-strand break repair via sister chromatid exchange", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "Q12433-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12441-1", "uniprot_id": "YD12A_YEAST", "mass": 49187.0, "length": 440, "protein_name": "Transposon Ty1-DR3 Gag polyprotein", "gene_name": "TY1A-DR3", "organism": "Yeast", "refseq_name": "gag protein", "refseq_ac": "NP_620388", "gene_names_uniprotkb": "TY1A-DR3; YD8142B.02c; YDRCTy1-2 GAG", "gene_names_refseq": "YDR210W-C", "protein_names_uniprotkb": "Transposon Ty1-DR3 Gag polyprotein; Gag-p45; Gag-p49; TY1A; TYA; Transposon Ty1 protein A; p54; p58", "protein_names_refseq": "gag protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR210C-C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "11884596;16093660;17563356;18407956;19779198;24374639;9169867;9582191", "class_list": "", "function": "Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA also has nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VSJ4", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0075523 viral translational frameshifting", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q12441-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12442-1", "uniprot_id": "IZH2_YEAST", "mass": 36279.0, "length": 317, "protein_name": "ADIPOR-like receptor IZH2", "gene_name": "IZH2", "organism": "Yeast", "refseq_name": "PAQR-type receptor", "refseq_ac": "NP_014641", "gene_names_uniprotkb": "IZH2; PHO36; UND327", "gene_names_refseq": "IZH2; PHO36", "protein_names_uniprotkb": "ADIPOR-like receptor IZH2; Phosphate metabolism protein 36", "protein_names_refseq": "PAQR-type receptor", "tax_id": 559292, "disease": "breast cancer (Disease Ontology:DOID:1612); hyperinsulinism (Disease Ontology:DOID:2018); prostate adenocarcinoma (Disease Ontology:DOID:2526); hyperglycemia (Disease Ontology:DOID:4195); macular degeneration (Disease Ontology:DOID:4448); end stage renal disease (Disease Ontology:DOID:783); obesity (Disease Ontology:DOID:9970)", "pathway": " (sce:YOL002C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "11916977;16847258;23749301;24374639;33481703;33491328;8896276;9169874;9774671", "class_list": "", "function": "Probable receptor, which is involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W265", "ec_number_list": "", "go_molecular_function": "GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006631 fatty acid metabolic process;GO:0009636 response to toxic substance;GO:0006882 intracellular zinc ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q12442-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12455-1", "uniprot_id": "SPSY_YEAST", "mass": 34091.0, "length": 300, "protein_name": "Spermine synthase SPE4", "gene_name": "SPE4", "organism": "Yeast", "refseq_name": "spermine synthase", "refseq_ac": "NP_013247", "gene_names_uniprotkb": "SPE4; L9634.5", "gene_names_refseq": "SPE4", "protein_names_uniprotkb": "Spermine synthase SPE4; 2.5.1.22; SPMSY; Spermidine aminopropyltransferase", "protein_names_refseq": "spermine synthase", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR146C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562106;15905473;18407956;20190278;24374639;32597660;33481703;33491328;9169871;9573363", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYE0;Q2VQW3", "ec_number_list": "2.5.1.22", "go_molecular_function": "GO:0016768 spermine synthase activity;GO:0004766 spermidine synthase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006597 spermine biosynthetic process;GO:0008295 spermidine biosynthetic process;GO:0015940 pantothenate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q12455-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12458-1", "uniprot_id": "YPR1_YEAST", "mass": 34755.0, "length": 312, "protein_name": "Aldehyde reductase YPR1", "gene_name": "YPR1", "organism": "Yeast", "refseq_name": "trifunctional aldehyde reductase/carbonyl reductase (NADPH)/glucose 1-dehydrogenase (NADP(+)) YPR1", "refseq_ac": "NP_010656", "gene_names_uniprotkb": "YPR1; D9481.8", "gene_names_refseq": "YPR1", "protein_names_uniprotkb": "Aldehyde reductase YPR1; 1.1.1.2; 2-methylbutyraldehyde reductase", "protein_names_refseq": "trifunctional aldehyde reductase/carbonyl reductase (NADPH)/glucose 1-dehydrogenase (NADP(+)) YPR1", "tax_id": 559292, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); ductal carcinoma in situ (Disease Ontology:DOID:0060074); B-lymphoblastic leukemia/lymphoma (Disease Ontology:DOID:0080630); castration-resistant prostate carcinoma (Disease Ontology:DOID:0080909); congenital bile acid synthesis defect 2 (Disease Ontology:DOID:0111069); 46,XY sex reversal 8 (Disease Ontology:DOID:0111773); prostate cancer (Disease Ontology:DOID:10283); stomach cancer (Disease Ontology:DOID:10534); pre-eclampsia (Disease Ontology:DOID:10591); polycystic ovary syndrome (Disease Ontology:DOID:11612); allergic disease (Disease Ontology:DOID:1205); leukemia (Disease Ontology:DOID:1240); breast cancer (Disease Ontology:DOID:1612); arteriosclerosis (Disease Ontology:DOID:2349); lung adenocarcinoma (Disease Ontology:DOID:3910); hyperglycemia (Disease Ontology:DOID:4195); hypokalemia (Disease Ontology:DOID:4500); T-cell acute lymphoblastic leukemia (Disease Ontology:DOID:5603); hepatocellular carcinoma (Disease Ontology:DOID:684); cataract (Disease Ontology:DOID:83); diabetic retinopathy (Disease Ontology:DOID:8947); type 2 diabetes mellitus (Disease Ontology:DOID:9352); diabetic neuropathy (Disease Ontology:DOID:9743); galactosemia (Disease Ontology:DOID:9870); obesity (Disease Ontology:DOID:9970)", "pathway": " (sce:YDR368W); (R-SCE-156590); (R-SCE-193144); (R-SCE-193368); (R-SCE-193775); (R-SCE-193807); (R-SCE-196108); (R-SCE-2162123); (R-SCE-5365859); (R-SCE-5652227); (R-SCE-5661270); (R-SCE-70221); (R-SCE-9757110)", "pathway_count": 13, "publication_count": 7, "publication_id_list": "12210903;14562106;18407956;24374639;33481703;33491328;9169867", "class_list": "", "function": "Aldehyde reductase with broad substrate specificity, catalyzing the NADPH-dependent reduction of aldehydes into the corresponding alcohols. In vitro, displays high specific activity towards 2-methylbutanal (2-methylbutyraldehyde), as well as other aldehydes such as hexanal (a toxic lipid peroxidation product and phytoalexin), but exhibits extremely low activity as a glycerol dehydrogenase. Seems to contribute to 2-methylbutanal reduction in vivo, and may therefore play a role in isoleucine catabolism and fusel alcohol formation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 25, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSZ9", "ec_number_list": "1.1.1.156;1.1.1.2;1.1.1.117;1.-.-.-;1.6.-.-;1.2.1.-", "go_molecular_function": "GO:0004032 aldose reductase (NADPH) activity;GO:0004090 carbonyl reductase (NADPH) activity;GO:0052588 diacetyl reductase ((S)-acetoin forming) (NAD+) activity;GO:0032018 2-methylbutanal reductase (NADPH) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0034599 cellular response to oxidative stress;GO:0042843 D-xylose catabolic process;GO:0019568 arabinose catabolic process;GO:0045149 acetoin metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q12458-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12471-1", "uniprot_id": "6P22_YEAST", "mass": 45318.0, "length": 397, "protein_name": "6-phosphofructo-2-kinase 2", "gene_name": "PFK27", "organism": "Yeast", "refseq_name": "6-phosphofructo-2-kinase", "refseq_ac": "NP_014505", "gene_names_uniprotkb": "PFK27", "gene_names_refseq": "PFK27", "protein_names_uniprotkb": "6-phosphofructo-2-kinase 2; 2.7.1.105; 6PF-2-K 2; Phosphofructokinase 2 II", "protein_names_refseq": "6-phosphofructo-2-kinase", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL136C); (R-SCE-9634600)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "14690591;18407956;22106047;23749301;24374639;33481703;33491328;8861205;8896270;9169874", "class_list": "", "function": "Synthesis of fructose 2,6-bisphosphate., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1T3", "ec_number_list": "3.1.3.46;2.7.1.105", "go_molecular_function": "GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity;GO:0005524 ATP binding;GO:0003873 6-phosphofructo-2-kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006110 regulation of glycolytic process;GO:0006000 fructose metabolic process;GO:0006003 fructose 2,6-bisphosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q12471-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12487-1", "uniprot_id": "RM23_YEAST", "mass": 18463.0, "length": 163, "protein_name": "Large ribosomal subunit protein uL13m", "gene_name": "MRPL23", "organism": "Yeast", "refseq_name": "mitochondrial 54S ribosomal protein uL13m MRPL23", "refseq_ac": "NP_014793", "gene_names_uniprotkb": "MRPL23; O3530", "gene_names_refseq": "MRPL23; uL13m", "protein_names_uniprotkb": "Large ribosomal subunit protein uL13m; 54S ribosomal protein L23, mitochondrial; YmL23", "protein_names_refseq": "mitochondrial 54S ribosomal protein uL13m MRPL23", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR150W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "12392552;14562095;14562106;14576278;17322287;22814378;24374639;24675956;25609543;9046089;9151978;9169874", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2K7", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005840 ribosome", "go_biological_process": "GO:0017148 negative regulation of translation;GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q12487-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12493-1", "uniprot_id": "NKP1_YEAST", "mass": 26976.0, "length": 238, "protein_name": "Inner kinetochore subunit NKP1", "gene_name": "NKP1", "organism": "Yeast", "refseq_name": "Nkp1p", "refseq_ac": "NP_010671", "gene_names_uniprotkb": "NKP1", "gene_names_refseq": "NKP1", "protein_names_uniprotkb": "Inner kinetochore subunit NKP1; Constitutive centromere-associated network protein NKP1; Non-essential kinetochore protein 1", "protein_names_refseq": "Nkp1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR383C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "12408861;12748633;14690591;18407956;22561346;24374639;29046335;32597660;33481703;33491328;34308839;9169867", "class_list": "", "function": "Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VT17", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0000776 kinetochore", "go_biological_process": "GO:0007059 chromosome segregation;GO:0008608 attachment of spindle microtubules to kinetochore;GO:0051301 cell division;GO:0051321 meiotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q12493-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12513-1", "uniprot_id": "TMA17_YEAST", "mass": 16771.0, "length": 150, "protein_name": "Translation machinery-associated protein 17", "gene_name": "TMA17", "organism": "Yeast", "refseq_name": "Tma17p", "refseq_ac": "NP_010173", "gene_names_uniprotkb": "TMA17; D2320", "gene_names_refseq": "ADC17; TMA17", "protein_names_uniprotkb": "Translation machinery-associated protein 17; ADC17; ATPase-dedicated chaperone of 17 kDa", "protein_names_refseq": "Tma17p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL110C)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "14562095;14562106;16702403;17330950;17563356;18407956;19779198;19795423;19823750;20702584;21126336;21177495;22218487;23749301;24374639;25042801;33481703;33491328;8923743;9169867", "class_list": "", "function": "ATPase-dedicated chaperone that assists the formation of the RPT6-RPT3 ATPase pair, an early step in proteasome assembly. Plays a key role in maintaining homeostatic proteasome levels and adjusting proteasome assembly when demands increase, such as during proteasome stresses. Function overlaps with RPN14., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRP0", "ec_number_list": "", "go_molecular_function": "GO:0008047 enzyme activator activity;GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005835 fatty acid synthase complex", "go_biological_process": "GO:0006633 fatty acid biosynthetic process;GO:0070682 proteasome regulatory particle assembly", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "Q12513-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12516-1", "uniprot_id": "SRF1_YEAST", "mass": 49580.0, "length": 437, "protein_name": "Regulator of phospholipase D SRF1", "gene_name": "SRF1", "organism": "Yeast", "refseq_name": "phospholipase D regulator", "refseq_ac": "NP_010149", "gene_names_uniprotkb": "SRF1; D2185", "gene_names_refseq": "SRF1", "protein_names_uniprotkb": "Regulator of phospholipase D SRF1; SPO14 regulatory factor 1", "protein_names_refseq": "phospholipase D regulator", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL133W)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "16278933;16847258;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;21347278;22218487;23749301;24374639;32597660;33229814;33481703;33491328;8972577;9169867", "class_list": "", "function": "Regulator of phospholipase D (SPO14) which is required for SPO14 catalytic activity in mitotic cells. Essential to buffer the toxic effects of C16:0 platelet activating factor., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 4, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 4, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 4, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6VRL6;P89897;Q7LGS2", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane;GO:0071944 cell periphery;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0016042 lipid catabolic process;GO:0043085 positive regulation of catalytic activity", "synthesized_glycan_count": 0, "hit_score": 2.8, "record_id": "Q12516-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12520-1", "uniprot_id": "HUT1_YEAST", "mass": 38075.0, "length": 339, "protein_name": "UDP-galactose transporter homolog 1", "gene_name": "HUT1", "organism": "Yeast", "refseq_name": "UDP-galactose transporter HUT1", "refseq_ac": "NP_015080", "gene_names_uniprotkb": "HUT1; MLF6", "gene_names_refseq": "HUT1", "protein_names_uniprotkb": "UDP-galactose transporter homolog 1; Multicopy suppressor of leflunomide-sensitivity protein 6", "protein_names_refseq": "UDP-galactose transporter HUT1", "tax_id": 559292, "disease": "hypomyelinating leukodystrophy 26 (Disease Ontology:DOID:0070403)", "pathway": " (sce:YPL244C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "11284009;11284010;11391470;16847258;17322287;24374639;9169875", "class_list": "", "function": "May be involved in specific transport of UDP-Gal from the cytosol to the Golgi lumen. Involved in the maintenance of optimal conditions for the folding of secretory pathway proteins in the endoplasmic reticulum. Overexpression confers resistance to the immunosuppressive drug, leflunomide., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W3C7", "ec_number_list": "", "go_molecular_function": "GO:0005459 UDP-galactose transmembrane transporter activity;GO:0005460 UDP-glucose transmembrane transporter activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0015786 UDP-glucose transmembrane transport;GO:0072334 UDP-galactose transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q12520-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12525-1", "uniprot_id": "MHT1_YEAST", "mass": 36715.0, "length": 324, "protein_name": "Homocysteine S-methyltransferase 1", "gene_name": "MHT1", "organism": "Yeast", "refseq_name": "S-adenosylmethionine-homocysteine S-methyltransferase MHT1", "refseq_ac": "NP_013038", "gene_names_uniprotkb": "MHT1; L0552", "gene_names_refseq": "MHT1", "protein_names_uniprotkb": "Homocysteine S-methyltransferase 1; 2.1.1.10; S-methylmethionine:homocysteine methyltransferase 1; SMM:Hcy S-methyltransferase 1", "protein_names_refseq": "S-adenosylmethionine-homocysteine S-methyltransferase MHT1", "tax_id": 559292, "disease": "fetal alcohol spectrum disorder (Disease Ontology:DOID:0050696); vitamin B12 deficiency (Disease Ontology:DOID:0050731); methylmalonic aciduria and homocystinuria type cblG (Disease Ontology:DOID:0050733); metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); alcohol-associated liver disease (Disease Ontology:DOID:0070658); spina bifida (Disease Ontology:DOID:0080016); hypertension (Disease Ontology:DOID:10763); urinary bladder cancer (Disease Ontology:DOID:11054); heart disease (Disease Ontology:DOID:114); autistic disorder (Disease Ontology:DOID:12849); pancreatic cancer (Disease Ontology:DOID:1793); IgA glomerulonephritis (Disease Ontology:DOID:2986); cerebral infarction (Disease Ontology:DOID:3526); retinoblastoma (Disease Ontology:DOID:768); abdominal aortic aneurysm (Disease Ontology:DOID:7693); hyperhomocysteinemia (Disease Ontology:DOID:9279); type 2 diabetes mellitus (Disease Ontology:DOID:9352); multiple myeloma (Disease Ontology:DOID:9538); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (sce:YLL062C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "11013242;14562095;14562106;17322287;24374639;33481703;33491328;9169871", "class_list": "", "function": "Homocysteine S-methyltransferase involved in the conversion of S-adenosylmethionine (AdoMet) to methionine to control the methionine/AdoMet ratio. Also converts S-methylmethionine (SMM) to methionine., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 19, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXU7", "ec_number_list": "2.1.1.10", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061627 S-methylmethionine-homocysteine S-methyltransferase activity;GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0032259 methylation;GO:0009086 methionine biosynthetic process;GO:0000096 sulfur amino acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q12525-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12672-1", "uniprot_id": "RL21B_YEAST", "mass": 18274.0, "length": 160, "protein_name": "Large ribosomal subunit protein eL21B", "gene_name": "RPL21B", "organism": "Yeast", "refseq_name": "60S ribosomal protein eL21 RPL21B", "refseq_ac": "NP_015246", "gene_names_uniprotkb": "RPL21B; LPF6W", "gene_names_refseq": "RPL21B", "protein_names_uniprotkb": "Large ribosomal subunit protein eL21B; 60S ribosomal protein L21-B", "protein_names_refseq": "60S ribosomal protein eL21 RPL21B", "tax_id": 559292, "disease": "hypotrichosis 12 (Disease Ontology:DOID:0110709)", "pathway": " (sce:YPL079W)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "14562095;14562106;19795423;19823750;20702584;22096102;22106047;23749301;24374639;24524803;32597660;9169875;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3T7", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005829 cytosol;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q12672-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12676-1", "uniprot_id": "FOLD_YEAST", "mass": 47851.0, "length": 427, "protein_name": "Dihydrofolate synthetase", "gene_name": "FOL3", "organism": "Yeast", "refseq_name": "dihydrofolate synthase", "refseq_ac": "NP_013831", "gene_names_uniprotkb": "FOL3; YM9718.12", "gene_names_refseq": "FOL3", "protein_names_uniprotkb": "Dihydrofolate synthetase; 6.3.2.12; DHFS", "protein_names_refseq": "dihydrofolate synthase", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR113W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10799479;11731153;14562095;14562106;22814378;24374639;33491328;9169872", "class_list": "", "function": "Glutamate-adding enzyme which catalyzes the binding of the first glutamyl side chain to dihydropteroate. Leads to the de nove synthesis of tetrahydrofolate., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZT6", "ec_number_list": "6.3.2.12", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004326 tetrahydrofolylpolyglutamate synthase activity;GO:0008841 dihydrofolate synthase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0006730 one-carbon metabolic process;GO:0009396 folic acid-containing compound biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q12676-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12751-1", "uniprot_id": "RTP1_YEAST", "mass": 113249.0, "length": 981, "protein_name": "RNA polymerase II assembly factor RTP1", "gene_name": "RTP1", "organism": "Yeast", "refseq_name": "Rtp1p", "refseq_ac": "NP_013910", "gene_names_uniprotkb": "RTP1; YM8010.15", "gene_names_refseq": "RTP1", "protein_names_uniprotkb": "RNA polymerase II assembly factor RTP1; Required for nuclear transport of RNA pol II protein 1; Transport and Golgi organization protein 6 homolog", "protein_names_refseq": "Rtp1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR185W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "23438601;24374639;2674684;33481703;33491328;7645348;9169872", "class_list": "", "function": "Required for the cytoplasmic assembly and the nuclear import of RNA polymerase II. May facilitate the starting interaction between RNA polymerase II subunits RPB2 and RPB3 and the subsequent interaction of the resulting complex with subunit RPB1. May also participate in the transport of RNA polymerase II through the nuclear pore complex., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W009", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0009306 protein secretion;GO:0006606 protein import into nucleus", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q12751-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2V2P9-1", "uniprot_id": "COX26_YEAST", "mass": 7452.0, "length": 66, "protein_name": "Cytochrome c oxidase subunit 26, mitochondrial", "gene_name": "COX26", "organism": "Yeast", "refseq_name": "Cox26p", "refseq_ac": "NP_001032575", "gene_names_uniprotkb": "COX26", "gene_names_refseq": "COX26", "protein_names_uniprotkb": "Cytochrome c oxidase subunit 26, mitochondrial", "protein_names_refseq": "Cox26p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR119W-A)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "12775844;24374639;27083394;27091403;30598554;9169867", "class_list": "", "function": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of COX2 and heme A of COX1 to the active site in COX1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSA5", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0045277 respiratory chain complex IV;GO:0098803 respiratory chain complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q2V2P9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3E705-1", "uniprot_id": "EFG1P_YEAST", "mass": 27121.0, "length": 233, "protein_name": "rRNA-processing protein EFG1", "gene_name": "EFG1", "organism": "Yeast", "refseq_name": "Efg1p", "refseq_ac": "NP_076891", "gene_names_uniprotkb": "EFG1; G9368; YGR272C", "gene_names_refseq": "EFG1; YGR272C", "protein_names_uniprotkb": "rRNA-processing protein EFG1; Exit from G1 protein 1", "protein_names_refseq": "Efg1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR271C-A)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "12837249;14562095;14562106;16510898;17287358;17322287;17330950;24374639;24909858;30516470;32597660;33481703;33491328;9133740;9169869", "class_list": "", "function": "Involved in rRNA processing. Required growth at elevated temperatures, resistance to hydroxyurea and for cell cycle progression., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VV49;P53328", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005730 nucleolus;GO:0030688 preribosome, small subunit precursor", "go_biological_process": "GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0071027 nuclear RNA surveillance;GO:0000321 re-entry into mitotic cell cycle after pheromone arrest", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q3E705-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3E790-1", "uniprot_id": "TSC3_YEAST", "mass": 9579.0, "length": 80, "protein_name": "Serine palmitoyltransferase-regulating protein TSC3", "gene_name": "TSC3", "organism": "Yeast", "refseq_name": "Tsc3p", "refseq_ac": "NP_116327", "gene_names_uniprotkb": "TSC3", "gene_names_refseq": "TSC3", "protein_names_uniprotkb": "Serine palmitoyltransferase-regulating protein TSC3; Temperature-sensitive CSG2-mutant suppressor protein 3", "protein_names_refseq": "Tsc3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR058C-A)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10713067;14562095;20182505;24374639;39490931;7813418", "class_list": "", "function": "Stimulates the activity of serine palmitoyltransferase (SPT), and thus plays a role in the biosynthesis of sphingolipids., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQ58", "ec_number_list": "", "go_molecular_function": "GO:0008047 enzyme activator activity", "go_cellular_component": "GO:0017059 serine palmitoyltransferase complex;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006666 3-keto-sphinganine metabolic process;GO:0090156 intracellular sphingolipid homeostasis;GO:0090154 positive regulation of sphingolipid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q3E790-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3E798-1", "uniprot_id": "MIM2_YEAST", "mass": 9985.0, "length": 87, "protein_name": "Mitochondrial import protein 2", "gene_name": "MIM2", "organism": "Yeast", "refseq_name": "Mim2p", "refseq_ac": "NP_076901", "gene_names_uniprotkb": "MIM2", "gene_names_refseq": "MIM2", "protein_names_uniprotkb": "Mitochondrial import protein 2", "protein_names_refseq": "Mim2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR099W-A)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "11152879;22467864;24374639;29897761;33491328;9169871", "class_list": "", "function": "Component of the MIM complex required for outer membrane protein import (PubMed:22467864). Involved in import of the subset of proteins with multiple alpha-helical transmembrane segments, including UGO1, TOM20 and FZO1 (PubMed:22467864)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYA0", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0140595 MIM complex", "go_biological_process": "GO:0045040 protein insertion into mitochondrial outer membrane;GO:0015031 protein transport;GO:0070096 mitochondrial outer membrane translocase complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q3E798-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3E7A4-1", "uniprot_id": "COXM2_YEAST", "mass": 12947.0, "length": 109, "protein_name": "COX assembly mitochondrial protein 2", "gene_name": "CMC2", "organism": "Yeast", "refseq_name": "Cmc2p", "refseq_ac": "NP_031358", "gene_names_uniprotkb": "CMC2", "gene_names_refseq": "CMC2", "protein_names_uniprotkb": "COX assembly mitochondrial protein 2; Cx9C motif-containing protein 2; Mitochondrial metallochaperone-like protein CMC2", "protein_names_refseq": "Cmc2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YBL059C-A)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562106;19703468;20220131;22814378;22984289;24374639;7813418;8154187", "class_list": "", "function": "Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration. May be involved in copper trafficking and distribution to mitochondrial COX and SOD1., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VPU0", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005758 mitochondrial intermembrane space", "go_biological_process": "GO:0033108 mitochondrial respiratory chain complex assembly;GO:0033617 mitochondrial respiratory chain complex IV assembly", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q3E7A4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3E7Y3-1", "uniprot_id": "RS22B_YEAST", "mass": 14626.0, "length": 130, "protein_name": "Small ribosomal subunit protein uS8B", "gene_name": "RPS22B", "organism": "Yeast", "refseq_name": "40S ribosomal protein uS8 RPS22B", "refseq_ac": "NP_013471", "gene_names_uniprotkb": "RPS22B; L8039.6; RPS24B", "gene_names_refseq": "RPS22B", "protein_names_uniprotkb": "Small ribosomal subunit protein uS8B; 40S ribosomal protein S22-B; RP50; S24; YP58; YS22", "protein_names_refseq": "40S ribosomal protein uS8 RPS22B", "tax_id": 559292, "disease": "intrinsic cardiomyopathy (Disease Ontology:DOID:0060036); Diamond-Blackfan anemia 20 (Disease Ontology:DOID:0111891)", "pathway": " (sce:YLR367W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562106;22096102;24374639;24524803;32597660;9169871;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ04;P04648", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005829 cytosol;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q3E7Y3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3E827-1", "uniprot_id": "LSO1_YEAST", "mass": 10869.0, "length": 93, "protein_name": "Protein LSO1", "gene_name": "LSO1", "organism": "Yeast", "refseq_name": "Lso1p", "refseq_ac": "NP_878106", "gene_names_uniprotkb": "LSO1", "gene_names_refseq": "LSO1", "protein_names_uniprotkb": "Protein LSO1; Late-annotated small open reading frame 1", "protein_names_refseq": "Lso1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR005C-A)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "12844361;24374639;26450372;8641269", "class_list": "", "function": "Likely to play a role in iron homeostasis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWI0", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006879 intracellular iron ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q3E827-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3E829-1", "uniprot_id": "CENPX_YEAST", "mass": 9050.0, "length": 80, "protein_name": "Inner kinetochore subunit MHF2", "gene_name": "MHF2", "organism": "Yeast", "refseq_name": "Mhf2p", "refseq_ac": "NP_878060", "gene_names_uniprotkb": "MHF2", "gene_names_refseq": "MHF2", "protein_names_uniprotkb": "Inner kinetochore subunit MHF2; CENP-X homolog; Constitutive centromere-associated network protein MHF2; MHF histone-fold complex subunit 2; MPH1-associated histone-fold protein 2", "protein_names_refseq": "Mhf2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL160C-A)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "12844361;20347428;22325783;22561346;24374639;32597660;33481703;33491328;34308839;9169867", "class_list": "", "function": "DNA-binding component of a FANCM-MHF complex involved in DNA damage repair and genome maintenance (PubMed:20347428). FANCM-MHF promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork (By similarity). Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly (PubMed:22561346)., [UniProtKB, UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRI9", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0071821 FANCM-MHF complex;GO:0005634 nucleus", "go_biological_process": "GO:0000712 resolution of meiotic recombination intermediates;GO:0051382 kinetochore assembly;GO:0006281 DNA repair;GO:0007059 chromosome segregation;GO:0006974 DNA damage response", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q3E829-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3E833-1", "uniprot_id": "PCC1_YEAST", "mass": 9993.0, "length": 88, "protein_name": "EKC/KEOPS complex subunit PCC1", "gene_name": "PCC1", "organism": "Yeast", "refseq_name": "chromatin DNA-binding EKC/KEOPS complex subunit PCC1", "refseq_ac": "NP_878113", "gene_names_uniprotkb": "PCC1", "gene_names_refseq": "PCC1", "protein_names_uniprotkb": "EKC/KEOPS complex subunit PCC1; Polarized growth chromatin-associated controller 1", "protein_names_refseq": "chromatin DNA-binding EKC/KEOPS complex subunit PCC1", "tax_id": 559292, "disease": "Galloway-Mowat syndrome 2 (Disease Ontology:DOID:0080244)", "pathway": " (sce:YKR095W-A)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "12775844;12844361;16874308;21183954;21459853;23258706;23620299;24374639;33491328;8196765", "class_list": "", "function": "Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. PCC1 functions as a dimerization module for the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXF6", "ec_number_list": "", "go_molecular_function": "GO:0031490 chromatin DNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0000785 chromatin;GO:0000408 EKC/KEOPS complex;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0000723 telomere maintenance;GO:1990145 maintenance of translational fidelity;GO:0002949 tRNA threonylcarbamoyladenosine modification", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q3E833-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3E834-1", "uniprot_id": "YOS1_YEAST", "mass": 9436.0, "length": 85, "protein_name": "Protein transport protein YOS1", "gene_name": "YOS1", "organism": "Yeast", "refseq_name": "Yos1p", "refseq_ac": "NP_219496", "gene_names_uniprotkb": "YOS1", "gene_names_refseq": "YOS1", "protein_names_uniprotkb": "Protein transport protein YOS1; YIP one suppressor protein 1", "protein_names_refseq": "Yos1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YER074W-A)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "15659647;21126336;23749301;24374639;32597660;33481703;33491328;9169868", "class_list": "", "function": "Required for protein transport between endoplasmic reticulum and Golgi apparatus., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLY0", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0030134 COPII-coated ER to Golgi transport vesicle;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0015031 protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q3E834-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3E835-1", "uniprot_id": "CENPS_YEAST", "mass": 10549.0, "length": 90, "protein_name": "Inner kinetochore subunit MHF1", "gene_name": "MHF1", "organism": "Yeast", "refseq_name": "Mhf1p", "refseq_ac": "NP_076910", "gene_names_uniprotkb": "MHF1", "gene_names_refseq": "MHF1", "protein_names_uniprotkb": "Inner kinetochore subunit MHF1; CENP-S homolog; Constitutive centromere-associated network protein MHF1; MHF histone-fold complex subunit 1; MPH1-associated histone-fold protein 1", "protein_names_refseq": "Mhf1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL086W-A)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "11152879;20347428;22325783;22561346;24374639;33491328;34308839;9169874", "class_list": "", "function": "dsDNA-binding component of a FANCM-MHF complex involved in DNA damage repair and genome maintenance (PubMed:20347428). FANCM-MHF promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork (By similarity). Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly (PubMed:22561346)., [UniProtKB, UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1Y2", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0071821 FANCM-MHF complex;GO:0005634 nucleus", "go_biological_process": "GO:0000712 resolution of meiotic recombination intermediates;GO:0006281 DNA repair;GO:0007059 chromosome segregation;GO:0006974 DNA damage response;GO:0031297 replication fork processing", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q3E835-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6Q595-1", "uniprot_id": "SCS22_YEAST", "mass": 19678.0, "length": 175, "protein_name": "Vesicle-associated membrane protein-associated protein SCS22", "gene_name": "SCS22", "organism": "Yeast", "refseq_name": "phospholipid metabolism-regulating protein SCS22", "refseq_ac": "NP_009461", "gene_names_uniprotkb": "SCS22", "gene_names_refseq": "SCS22", "protein_names_uniprotkb": "Vesicle-associated membrane protein-associated protein SCS22; VAMP-associated protein SCS22; VAP homolog 2", "protein_names_refseq": "phospholipid metabolism-regulating protein SCS22", "tax_id": 559292, "disease": "amyotrophic lateral sclerosis type 8 (Disease Ontology:DOID:0050752); autosomal dominant adult-onset proximal spinal muscular atrophy (Disease Ontology:DOID:0111194); spinal muscular atrophy (Disease Ontology:DOID:12377); neurodegenerative disease (Disease Ontology:DOID:1289); motor neuron disease (Disease Ontology:DOID:231); amyotrophic lateral sclerosis (Disease Ontology:DOID:332)", "pathway": " (sce:YBL091C-A); (R-SCE-9013106)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "12844361;14562106;15668246;17322287;24374639;32597660;33491328;7502586;7813418", "class_list": "", "function": "Targets proteins containing a FFAT motif to membranes (By similarity). Involved in regulation of phospholipid metabolism., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VPR2", "ec_number_list": "", "go_molecular_function": "GO:0043495 protein-membrane adaptor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0090158 endoplasmic reticulum membrane organization;GO:0060304 regulation of phosphatidylinositol dephosphorylation;GO:0008654 phospholipid biosynthetic process;GO:0061709 reticulophagy;GO:0061817 endoplasmic reticulum-plasma membrane tethering", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q6Q595-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8TGJ3-1", "uniprot_id": "KISH_YEAST", "mass": 8196.0, "length": 72, "protein_name": "Protein Kish", "gene_name": "KSH1", "organism": "Yeast", "refseq_name": "Ksh1p", "refseq_ac": "NP_878158", "gene_names_uniprotkb": "KSH1", "gene_names_refseq": "KSH1", "protein_names_uniprotkb": "Protein Kish", "protein_names_refseq": "Ksh1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL024C-A)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "11753363;19942856;24374639;26928762;29897761;9169873", "class_list": "", "function": "Involved in the early part of the secretory pathway., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1F4", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0009306 protein secretion", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q8TGJ3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q99186-1", "uniprot_id": "AP2M_YEAST", "mass": 55387.0, "length": 491, "protein_name": "AP-2 complex subunit mu", "gene_name": "APM4", "organism": "Yeast", "refseq_name": "Apm4p", "refseq_ac": "NP_014579", "gene_names_uniprotkb": "APM4; AMP1; O1210", "gene_names_refseq": "AMP1; APM4", "protein_names_uniprotkb": "AP-2 complex subunit mu; Adaptin medium chain APM4; Clathrin assembly protein complex 2 mu medium chain; Clathrin coat assembly protein AP50; Clathrin coat-associated protein AP50; Mu2-adaptin; Plasma membrane adaptor AP-2 50 kDa protein", "protein_names_refseq": "Apm4p", "tax_id": 559292, "disease": "autosomal dominant intellectual developmental disorder 60 with seizures (Disease Ontology:DOID:0061050); heroin dependence (Disease Ontology:DOID:9976)", "pathway": " (sce:YOL062C); (R-SCE-190873); (R-SCE-196025); (R-SCE-437239); (R-SCE-8856825); (R-SCE-8856828); (R-SCE-8866427); (R-SCE-8964038)", "pathway_count": 8, "publication_count": 17, "publication_id_list": "10564262;14562106;17287358;17330950;17563356;18407956;19779198;19795423;19823750;20702584;23749301;24374639;32597660;33481703;33491328;8789261;9169874", "class_list": "", "function": "Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W205", "ec_number_list": "", "go_molecular_function": "GO:0035615 clathrin adaptor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0030122 AP-2 adaptor complex;GO:0030121 AP-1 adaptor complex", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0072583 clathrin-dependent endocytosis;GO:0006896 Golgi to vacuole transport", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q99186-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q99188-1", "uniprot_id": "RGS2_YEAST", "mass": 35100.0, "length": 309, "protein_name": "Regulator of G protein signaling 2", "gene_name": "RGS2", "organism": "Yeast", "refseq_name": "GTPase-activating protein RGS2", "refseq_ac": "NP_014750", "gene_names_uniprotkb": "RGS2; YOR3224w", "gene_names_refseq": "RGS2", "protein_names_uniprotkb": "Regulator of G protein signaling 2", "protein_names_refseq": "GTPase-activating protein RGS2", "tax_id": 559292, "disease": "colorectal adenocarcinoma (Disease Ontology:DOID:0050861); hypertension (Disease Ontology:DOID:10763); essential hypertension (Disease Ontology:DOID:10825)", "pathway": " (sce:YOR107W); (R-SCE-418594)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "10523302;14562095;17322287;24374639;9169874;9200815", "class_list": "", "function": "GTPase activating protein for GPA2. Negatively down-regulates glucose-induced cAMP signaling via GPA2., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2G6", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "GO:0045744 negative regulation of G protein-coupled receptor signaling pathway;GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q99188-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q99189-1", "uniprot_id": "MTR10_YEAST", "mass": 110745.0, "length": 972, "protein_name": "mRNA transport regulator MTR10", "gene_name": "MTR10", "organism": "Yeast", "refseq_name": "mRNA transport regulator MTR10", "refseq_ac": "NP_014803", "gene_names_uniprotkb": "MTR10", "gene_names_refseq": "KAP111; MTR10", "protein_names_uniprotkb": "mRNA transport regulator MTR10", "protein_names_refseq": "mRNA transport regulator MTR10", "tax_id": 559292, "disease": "autosomal dominant limb-girdle muscular dystrophy type 2 (Disease Ontology:DOID:0110304)", "pathway": " (sce:YOR160W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562106;19795423;19823750;24374639;33491328;9046089;9169874", "class_list": "", "function": "Involved in mRNA transport from nucleus to cytoplasm., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2L7", "ec_number_list": "", "go_molecular_function": "GO:0031267 small GTPase binding;GO:0008139 nuclear localization sequence binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0034399 nuclear periphery", "go_biological_process": "GO:0061015 snRNA import into nucleus;GO:0006404 RNA import into nucleus;GO:0006606 protein import into nucleus;GO:0006403 RNA localization;GO:0051031 tRNA transport", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q99189-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q99288-1", "uniprot_id": "DET1_YEAST", "mass": 39172.0, "length": 334, "protein_name": "Broad-range acid phosphatase DET1", "gene_name": "DET1", "organism": "Yeast", "refseq_name": "acid phosphatase DET1", "refseq_ac": "NP_010336", "gene_names_uniprotkb": "DET1; D4202", "gene_names_refseq": "DET1", "protein_names_uniprotkb": "Broad-range acid phosphatase DET1; 3.1.3.-; Decreased ergosterol transport protein 1", "protein_names_refseq": "acid phosphatase DET1", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR051C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562095;14562106;18407956;19060182;19753119;24374639;33491328;8789263;9169867", "class_list": "", "function": "Metal-independent, broad-range acid phosphatase. Involved, either directly or indirectly, in the bidirectional transport of sterols between the endoplasmic reticulum and the plasma membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS38;P87337;Q05314;Q7LHX4", "ec_number_list": "", "go_molecular_function": "GO:0003993 acid phosphatase activity;GO:0016791 phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0032366 intracellular sterol transport", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q99288-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q99297-1", "uniprot_id": "ODC2_YEAST", "mass": 34007.0, "length": 307, "protein_name": "Mitochondrial 2-oxodicarboxylate carrier 2", "gene_name": "ODC2", "organism": "Yeast", "refseq_name": "mitochondrial 2-oxodicarboxylate carrier", "refseq_ac": "NP_014865", "gene_names_uniprotkb": "ODC2; YOR50-12", "gene_names_refseq": "ODC2", "protein_names_uniprotkb": "Mitochondrial 2-oxodicarboxylate carrier 2", "protein_names_refseq": "mitochondrial 2-oxodicarboxylate carrier", "tax_id": 559292, "disease": "mitochondrial DNA depletion syndrome 18 (Disease Ontology:DOID:0070449)", "pathway": " (sce:YOR222W)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "11013234;24374639;8840505;9169874", "class_list": "", "function": "Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2-oxoglutarate, adipate, glutarate, 2-oxopimelate, oxaloacetate, citrate and malate. The main physiological role is probably to supply 2-oxoadipate and 2-oxoglutarate from the mitochondrial matrix to the cytosol where they are used in the biosynthesis of lysine and glutamate, respectively, and in lysine catabolism., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W2S7;O13594", "ec_number_list": "", "go_molecular_function": "GO:0005471 ATP:ADP antiporter activity;GO:0005313 L-glutamate transmembrane transporter activity;GO:0015183 L-aspartate transmembrane transporter activity;GO:0005310 dicarboxylic acid transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006839 mitochondrial transport;GO:0015810 aspartate transmembrane transport;GO:0015813 L-glutamate transmembrane transport;GO:0043490 malate-aspartate shuttle;GO:0140021 mitochondrial ADP transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q99297-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q99316-1", "uniprot_id": "MPD2_YEAST", "mass": 32401.0, "length": 277, "protein_name": "Protein disulfide isomerase MPD2", "gene_name": "MPD2", "organism": "Yeast", "refseq_name": "protein disulfide isomerase MPD2", "refseq_ac": "NP_014553", "gene_names_uniprotkb": "MPD2; O0941", "gene_names_refseq": "MPD2", "protein_names_uniprotkb": "Protein disulfide isomerase MPD2; 5.3.4.1", "protein_names_refseq": "protein disulfide isomerase MPD2", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL088C); (R-SCE-6798695)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "10549279;14562095;14562106;24374639;8533473;9169874;9367834", "class_list": "", "function": "Non essential disulfide isomerase, which participates in the folding of proteins containing disulfide bonds. May be involved in glycosylation, prolyl hydroxylation and triglyceride transfer. Able to fold proteins by being directly oxidized by ERO1., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1Y0", "ec_number_list": "3.5.3.1;2.4.1.1;2.7.11.13;3.6.4.6;1.11.1.27;1.11.1.25;1.1.1.205;4.6.1.19;3.-.-.-;5.3.4.1", "go_molecular_function": "GO:0015035 protein-disulfide reductase activity;GO:0003756 protein disulfide isomerase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q99316-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q99332-1", "uniprot_id": "HPH1_YEAST", "mass": 67293.0, "length": 602, "protein_name": "Protein HPH1", "gene_name": "FRT1", "organism": "Yeast", "refseq_name": "Frt1p", "refseq_ac": "NP_014969", "gene_names_uniprotkb": "FRT1; HPH1; O6159", "gene_names_refseq": "FRT1; HPH1", "protein_names_uniprotkb": "Protein HPH1; Functionally related to TCP1 protein 1; High pH protein 1", "protein_names_refseq": "Frt1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR324C)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "12514182;14562106;15189990;17563356;18407956;19684113;19779198;22814378;23749301;24374639;32597660;33481703;33491328;8896266;9169874", "class_list": "", "function": "Calcineurin-dependent protein required for growth under high NaCl, alkaline pH and cell wall stress., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 24, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W322", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0071469 cellular response to alkaline pH;GO:0071472 cellular response to salt stress;GO:0031204 post-translational protein targeting to membrane, translocation", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q99332-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q99344-1", "uniprot_id": "UBA3_YEAST", "mass": 33278.0, "length": 299, "protein_name": "NEDD8-activating enzyme E1 catalytic subunit", "gene_name": "UBA3", "organism": "Yeast", "refseq_name": "NEDD8-activating protein UBA3", "refseq_ac": "NP_015391", "gene_names_uniprotkb": "UBA3; YP9499.21", "gene_names_refseq": "UBA3", "protein_names_uniprotkb": "NEDD8-activating enzyme E1 catalytic subunit; 6.2.1.64; RUB1-activating enzyme E1; Ubiquitin-activating enzyme E1 3; Ubiquitin-like protein-activating enzyme", "protein_names_refseq": "NEDD8-activating protein UBA3", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR066W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562106;17322287;24374639;33491328;9169875;9545234", "class_list": "", "function": "Catalytic subunit of the dimeric UBA3-ULA1 E1 enzyme. E1 activates NEDD8/RUB1 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBC12., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W470;E9P8X1", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0019781 NEDD8 activating enzyme activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0045116 protein neddylation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q99344-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q99382-1", "uniprot_id": "ENV10_YEAST", "mass": 20742.0, "length": 181, "protein_name": "SRP-independent targeting protein 2", "gene_name": "ENV10", "organism": "Yeast", "refseq_name": "Snd2p", "refseq_ac": "NP_013166", "gene_names_uniprotkb": "ENV10; L2180; SND2", "gene_names_refseq": "ENV10; SND2", "protein_names_uniprotkb": "SRP-independent targeting protein 2; Late endosome and vacuole interface protein 10", "protein_names_refseq": "Snd2p", "tax_id": 559292, "disease": "syndromic intellectual disability (Disease Ontology:DOID:0050888)", "pathway": " (sce:YLR065C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "16847258;17322287;21912603;24374639;27905431;9169871", "class_list": "", "function": "Functions in the SND pathway, a SRP (signal recognition particle) and GET (guided entry of tail-anchored proteins) independent pathway for targeting a broad range of substrate proteins to the endoplasmic reticulum. SND functions in parallel to GET in targeting proteins with downstream hydrophobic motifs (PubMed:27905431). Involved in vacuolar processing and morphology (PubMed:21912603)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VY66;Q6Q5C1", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0005773 vacuole", "go_biological_process": "GO:0015031 protein transport;GO:0006624 vacuolar protein processing", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q99382-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q99393-1", "uniprot_id": "IZH4_YEAST", "mass": 36608.0, "length": 312, "protein_name": "ADIPOR-like receptor IZH4", "gene_name": "IZH4", "organism": "Yeast", "refseq_name": "Izh4p", "refseq_ac": "NP_014540", "gene_names_uniprotkb": "IZH4", "gene_names_refseq": "IZH4", "protein_names_uniprotkb": "ADIPOR-like receptor IZH4; Implicated in zinc homeostasis protein 4", "protein_names_refseq": "Izh4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL101C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "12524434;14562095;15060275;16847258;17322287;24374639;33481703;33491328;7502582;9169874", "class_list": "", "function": "ADIPOR-like receptor involved in zinc metabolism either by altering membrane sterol content or by directly altering cellular zinc levels., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1W7;Q6B2Z2", "ec_number_list": "", "go_molecular_function": "GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005789 endoplasmic reticulum membrane;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0006882 intracellular zinc ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q99393-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9P305-1", "uniprot_id": "IGO2_YEAST", "mass": 14395.0, "length": 131, "protein_name": "mRNA stability protein IGO2", "gene_name": "IGO2", "organism": "Yeast", "refseq_name": "phosphatase regulator", "refseq_ac": "NP_036194", "gene_names_uniprotkb": "IGO2", "gene_names_refseq": "IGO2", "protein_names_uniprotkb": "mRNA stability protein IGO2; Initiation of G zero protein 2", "protein_names_refseq": "phosphatase regulator", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR132W-A); (R-SCE-2465910)", "pathway_count": 2, "publication_count": 24, "publication_id_list": "11875433;14562095;14562106;15665377;17287358;17563356;18407956;19684113;19779198;19795423;19823750;20471941;21126336;21177495;22218487;22814378;23749301;24374639;30516470;32597660;33481703;33491328;34965436;8091229", "class_list": "", "function": "Required for TORC1 to properly control gene expression and chronological life span. Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 23, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DL81", "ec_number_list": "", "go_molecular_function": "GO:0044877 protein-containing complex binding;GO:0004864 protein phosphatase inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0034605 cellular response to heat;GO:1903452 positive regulation of G1 to G0 transition;GO:1901992 positive regulation of mitotic cell cycle phase transition;GO:1900152 negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "Q9P305-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P07253-1", "uniprot_id": "CBP6_YEAST", "mass": 18679.0, "length": 162, "protein_name": "Cytochrome B pre-mRNA-processing protein 6", "gene_name": "CBP6", "organism": "Yeast", "refseq_name": "Cbp6p", "refseq_ac": "NP_009678", "gene_names_uniprotkb": "CBP6; YBR0916", "gene_names_refseq": "CBP6", "protein_names_uniprotkb": "Cytochrome B pre-mRNA-processing protein 6", "protein_names_refseq": "Cbp6p", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR120C); (R-SCE-9865878)", "pathway_count": 2, "publication_count": 12, "publication_id_list": "14562095;14562106;14576278;17322287;17761666;22814378;24374639;2981859;33481703;33491328;7813418;7900426", "class_list": "", "function": "This protein is involved in processing of the 5' terminus and the intervening sequences of cytochrome b pre-mRNA., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQB8;E9P8V5", "ec_number_list": "", "go_molecular_function": "GO:0043022 ribosome binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0005761 mitochondrial ribosome;GO:0061671 Cbp3p-Cbp6 complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0050821 protein stabilization;GO:0034551 mitochondrial respiratory chain complex III assembly;GO:0070131 positive regulation of mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P07253-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P10869-1", "uniprot_id": "AK_YEAST", "mass": 58110.0, "length": 527, "protein_name": "Aspartokinase", "gene_name": "HOM3", "organism": "Yeast", "refseq_name": "aspartate kinase", "refseq_ac": "NP_010972", "gene_names_uniprotkb": "HOM3", "gene_names_refseq": "BOR1; HOM3; SIL4; THR3", "protein_names_uniprotkb": "Aspartokinase; 2.7.2.4; Aspartate kinase", "protein_names_refseq": "aspartate kinase", "tax_id": 559292, "disease": "", "pathway": " (sce:YER052C)", "pathway_count": 1, "publication_count": 28, "publication_id_list": "10509015;14562106;14623312;15358146;17287358;17330950;18407956;19684113;19779198;19795423;19823750;20305002;20305003;20702584;21126336;21177495;2168408;23749301;24374639;24909858;27821475;2892836;32597660;33481703;33491328;34965436;9169868;9315655", "class_list": "", "function": "Phosphorylates aspartate, the first step in the biosynthesis of amino acids that derive from aspartate (the aspartate family of amino acids), including methioinine and threonine, the latter of which is a precursor to isoleucine., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 12, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLV4", "ec_number_list": "2.7.2.4", "go_molecular_function": "GO:0005524 ATP binding;GO:0004072 aspartate kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0009086 methionine biosynthetic process;GO:0071266 'de novo' L-methionine biosynthetic process;GO:0009088 threonine biosynthetic process;GO:0009090 homoserine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 2.9, "record_id": "P10869-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P12887-1", "uniprot_id": "UNG_YEAST", "mass": 40471.0, "length": 359, "protein_name": "Uracil-DNA glycosylase", "gene_name": "UNG1", "organism": "Yeast", "refseq_name": "uracil-DNA glycosylase", "refseq_ac": "NP_013691", "gene_names_uniprotkb": "UNG1", "gene_names_refseq": "UNG1", "protein_names_uniprotkb": "Uracil-DNA glycosylase; 3.2.2.27; UDG", "protein_names_refseq": "uracil-DNA glycosylase", "tax_id": 559292, "disease": "immunodeficiency with hyper IgM type 5 (Disease Ontology:DOID:0060759); dysgammaglobulinemia (Disease Ontology:DOID:11702)", "pathway": " (sce:YML021C); (R-SCE-110329)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "11812822;14562106;17322287;17934734;1938887;23749301;24374639;2644266;7031606;9169872", "class_list": "", "function": "Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. Not involved in strand-directed mismatch repair., [UniProtKB, PubMed, PubMed, PubMed, PubMed, HAMAP]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VZF3;E9P912", "ec_number_list": "3.2.2.27", "go_molecular_function": "GO:0004844 uracil DNA N-glycosylase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion", "go_biological_process": "GO:0006281 DNA repair;GO:0097510 base-excision repair, AP site formation via deaminated base removal", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P12887-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P13099-1", "uniprot_id": "TOP3_YEAST", "mass": 74371.0, "length": 656, "protein_name": "DNA topoisomerase 3", "gene_name": "TOP3", "organism": "Yeast", "refseq_name": "DNA topoisomerase 3", "refseq_ac": "NP_013335", "gene_names_uniprotkb": "TOP3; EDR1; L8083.3", "gene_names_refseq": "EDR1; TOP3", "protein_names_uniprotkb": "DNA topoisomerase 3; 5.6.2.1; DNA topoisomerase III", "protein_names_refseq": "DNA topoisomerase 3", "tax_id": 559292, "disease": "autosomal recessive progressive external ophthalmoplegia with mitochondrial DNA deletions 5 (Disease Ontology:DOID:0111524)", "pathway": " (sce:YLR234W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562106;15889139;15899853;24374639;2546682;8336724;9169871", "class_list": "", "function": "Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand than undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity). Essential for proper chromosome segregation in both meiosis and mitosis. Weakly relaxes negative supercoils and displays a distinct preference for binding single-stranded DNA. The TOP3-SGS1 protein complex may function as a eukaryotic reverse gyrase introducing positive supercoils into extrachromosomal ribosomal DNA rings., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYN4", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003917 DNA topoisomerase type I (single strand cut, ATP-independent) activity;GO:0003916 DNA topoisomerase activity;GO:0140226 RNA topoisomerase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0031422 RecQ family helicase-topoisomerase III complex", "go_biological_process": "GO:0000018 regulation of DNA recombination;GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0000724 double-strand break repair via homologous recombination;GO:0006265 DNA topological change", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P13099-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P13134-1", "uniprot_id": "KEX2_YEAST", "mass": 90003.0, "length": 814, "protein_name": "Kexin", "gene_name": "KEX2", "organism": "Yeast", "refseq_name": "kexin KEX2", "refseq_ac": "NP_014161", "gene_names_uniprotkb": "KEX2; N1122; QDS1", "gene_names_refseq": "KEX2; QDS1; SRB1; VMA45", "protein_names_uniprotkb": "Kexin; 3.4.21.61; Protease KEX2; Proteinase YSCF", "protein_names_refseq": "kexin KEX2", "tax_id": 559292, "disease": "visceral heterotaxy (Disease Ontology:DOID:0050545); colorectal adenocarcinoma (Disease Ontology:DOID:0050861); proprotein convertase 1/3 deficiency (Disease Ontology:DOID:0111698); sciatic neuropathy (Disease Ontology:DOID:11446); hypothyroidism (Disease Ontology:DOID:1459); VACTERL association (Disease Ontology:DOID:14679); alcohol use disorder (Disease Ontology:DOID:1574); islet cell tumor (Disease Ontology:DOID:1799); colon adenocarcinoma (Disease Ontology:DOID:234); arteriosclerosis (Disease Ontology:DOID:2349); endocrine system disease (Disease Ontology:DOID:28); hyperglycemia (Disease Ontology:DOID:4195); schizophrenia (Disease Ontology:DOID:5419); hyperthyroidism (Disease Ontology:DOID:7998); type 2 diabetes mellitus (Disease Ontology:DOID:9352); primary ciliary dyskinesia (Disease Ontology:DOID:9562); obesity (Disease Ontology:DOID:9970)", "pathway": " (sce:YNL238W); (R-SCE-2173796)", "pathway_count": 2, "publication_count": 12, "publication_id_list": "12779325;1544507;1736307;1918142;23408788;24374639;2646633;2845974;33481703;33491328;8896273;9169873", "class_list": "", "function": "Processing of precursors of alpha-factors and killer toxin., [UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 17, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "D6W0V5", "ec_number_list": "3.4.21.61", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005802 trans-Golgi network;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0016485 protein processing;GO:0007323 peptide pheromone maturation", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P13134-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P13185-1", "uniprot_id": "KIN1_YEAST", "mass": 120071.0, "length": 1064, "protein_name": "Serine/threonine protein kinase KIN1", "gene_name": "KIN1", "organism": "Yeast", "refseq_name": "serine/threonine protein kinase KIN1", "refseq_ac": "NP_010407", "gene_names_uniprotkb": "KIN1; YD9727.17", "gene_names_refseq": "KIN1", "protein_names_uniprotkb": "Serine/threonine protein kinase KIN1; 2.7.11.1", "protein_names_refseq": "serine/threonine protein kinase KIN1", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR122W); (R-SCE-1632852); (R-SCE-380972)", "pathway_count": 3, "publication_count": 26, "publication_id_list": "14562106;15563607;15665377;1652871;17287358;17330950;17563356;18407956;19779198;19795423;19823750;20489023;20702584;21177495;22218487;23749301;24374639;2957690;30201804;32597660;33229814;33481703;33491328;8020610;8203145;9169867", "class_list": "", "function": "Serine/threonine protein kinase involved in the regulation of exocytosis. Induces phosphorylation of SEC9 and its release from the plasma membrane to the cytosol., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 7, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 7, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 7, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 50, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "D6VSA8;Q04606", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.1.137;2.7.11.23;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "GO:1903896 positive regulation of IRE1-mediated unfolded protein response;GO:0006887 exocytosis;GO:0045921 positive regulation of exocytosis", "synthesized_glycan_count": 0, "hit_score": 3.5, "record_id": "P13185-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P13186-1", "uniprot_id": "KIN2_YEAST", "mass": 128338.0, "length": 1147, "protein_name": "Serine/threonine-protein kinase KIN2", "gene_name": "KIN2", "organism": "Yeast", "refseq_name": "serine/threonine protein kinase KIN2", "refseq_ac": "NP_013197", "gene_names_uniprotkb": "KIN2; L8004.3", "gene_names_refseq": "KIN2", "protein_names_uniprotkb": "Serine/threonine-protein kinase KIN2; 2.7.11.1", "protein_names_refseq": "serine/threonine protein kinase KIN2", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR096W); (R-SCE-1632852); (R-SCE-380972)", "pathway_count": 3, "publication_count": 27, "publication_id_list": "15563607;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20489023;20702584;21126336;21177495;22218487;23749301;24374639;27821475;2957690;30201804;32597660;33229814;33481703;33491328;34965436;8020610;8203145;9169871", "class_list": "", "function": "Serine/threonine protein kinase involved in the regulation of exocytosis. Induces phosphorylation of SEC9 and its release from the plasma membrane to the cytosol., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 8, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 8, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 8, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 53, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "D6VY96;Q12384", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.1.137;2.7.11.23;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005934 cellular bud tip;GO:0005935 cellular bud neck", "go_biological_process": "GO:1903896 positive regulation of IRE1-mediated unfolded protein response;GO:0006887 exocytosis;GO:0045921 positive regulation of exocytosis", "synthesized_glycan_count": 0, "hit_score": 3.7, "record_id": "P13186-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P13259-1", "uniprot_id": "PCY1_YEAST", "mass": 49406.0, "length": 424, "protein_name": "Choline-phosphate cytidylyltransferase", "gene_name": "PCT1", "organism": "Yeast", "refseq_name": "choline-phosphate cytidylyltransferase", "refseq_ac": "NP_011718", "gene_names_uniprotkb": "PCT1; CCT1; CCT; G7729", "gene_names_refseq": "BSR2; CCT1; PCT1", "protein_names_uniprotkb": "Choline-phosphate cytidylyltransferase; 2.7.7.15; CCT; CTP:phosphocholine cytidylyltransferase; CT; Phosphorylcholine transferase", "protein_names_refseq": "choline-phosphate cytidylyltransferase", "tax_id": 559292, "disease": "congenital generalized lipodystrophy (Disease Ontology:DOID:0050585); spondylometaphyseal dysplasia with cone-rod dystrophy (Disease Ontology:DOID:0112300)", "pathway": " (sce:YGR202C); (R-SCE-1483191)", "pathway_count": 2, "publication_count": 24, "publication_id_list": "14562106;15665377;17287358;17322287;17330950;17563356;18407956;19779198;19795423;19823750;20702584;21126336;21177495;22218487;22814378;23749301;24374639;2826147;30516470;32597660;33481703;33491328;8904340;9169869", "class_list": "", "function": "Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUY4", "ec_number_list": "2.7.7.15", "go_molecular_function": "GO:0004105 choline-phosphate cytidylyltransferase activity;GO:0031210 phosphatidylcholine binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0016020 membrane;GO:0042564 NLS-dependent protein nuclear import complex", "go_biological_process": "GO:0006657 CDP-choline pathway;GO:0006656 phosphatidylcholine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "P13259-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P13382-1", "uniprot_id": "DPOLA_YEAST", "mass": 166809.0, "length": 1468, "protein_name": "DNA polymerase alpha catalytic subunit A", "gene_name": "POL1", "organism": "Yeast", "refseq_name": "DNA-directed DNA polymerase alpha catalytic subunit POL1", "refseq_ac": "NP_014297", "gene_names_uniprotkb": "POL1; CDC17; N2181", "gene_names_refseq": "CDC17; CRT5; HPR3; POL1", "protein_names_uniprotkb": "DNA polymerase alpha catalytic subunit A; 2.7.7.7; DNA polymerase I subunit A; DNA polymerase alpha:primase complex p180 subunit; DNA polymerase-primase complex p180 subunit; Pol alpha-primase complex p180 subunit", "protein_names_refseq": "DNA-directed DNA polymerase alpha catalytic subunit POL1", "tax_id": 559292, "disease": "X-linked reticulate pigmentary disorder (Disease Ontology:DOID:0111834); Van Esch-O'Driscoll syndrome (Disease Ontology:DOID:0111840)", "pathway": " (sce:YNL102W); (R-SCE-113501); (R-SCE-68952); (R-SCE-68962); (R-SCE-69091); (R-SCE-69166); (R-SCE-69183)", "pathway_count": 7, "publication_count": 34, "publication_id_list": "10898792;14562106;16675460;17287358;17330950;17563356;18407956;19494830;19684113;19779198;19795423;19823750;20190278;20702584;21126336;21177495;22119860;22218487;22814378;23749301;24374639;30516470;3061469;31488849;32597660;3287376;33229814;33481703;33491328;8446029;8621497;8701612;9169873;9199353", "class_list": "", "function": "Catalytic component of DNA polymerase alpha, which in complex with DNA primase (DNA polymerase alpha:primase) constitutes a replicative polymerase (PubMed:10898792, PubMed:22119860, PubMed:31488849). POL1 has a role in promoting telomere replication during interaction with CDC13 (PubMed:10898792)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 5, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 5, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 5, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 36, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 2, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "D6W177", "ec_number_list": "2.7.7.7;3.1.26.4;2.7.7.49;3.4.23.-;2.7.11.22;2.7.11.1;2.7.7.-;3.1.11.-;3.6.4.12;3.1.-.-", "go_molecular_function": "GO:0003688 DNA replication origin binding;GO:0003887 DNA-directed DNA polymerase activity;GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0051539 4 iron, 4 sulfur cluster binding", "go_cellular_component": "GO:0005658 alpha DNA polymerase:primase complex;GO:0005739 mitochondrion;GO:0005657 replication fork", "go_biological_process": "GO:0006278 RNA-templated DNA biosynthetic process;GO:0006272 leading strand elongation;GO:0006273 lagging strand elongation;GO:0006260 DNA replication;GO:0006302 double-strand break repair", "synthesized_glycan_count": 0, "hit_score": 4.1, "record_id": "P13382-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P13393-1", "uniprot_id": "TBP_YEAST", "mass": 27003.0, "length": 240, "protein_name": "TATA-box-binding protein", "gene_name": "SPT15", "organism": "Yeast", "refseq_name": "TATA-binding protein", "refseq_ac": "NP_011075", "gene_names_uniprotkb": "SPT15; BTF1; TBP1", "gene_names_refseq": "BTF1; SPT15; TBP1", "protein_names_uniprotkb": "TATA-box-binding protein; TATA sequence-binding protein; TATA-binding factor; TATA-box factor; TBP; Transcription factor D; Transcription initiation factor TFIID TBP subunit", "protein_names_refseq": "TATA-binding protein", "tax_id": 559292, "disease": "sleep apnea (Disease Ontology:DOID:0050847); spinocerebellar ataxia 17 (Disease Ontology:DOID:0050967); late onset Parkinson's disease (Disease Ontology:DOID:0060892); Alzheimer's disease (Disease Ontology:DOID:10652); Huntington's disease (Disease Ontology:DOID:12858); neurodegenerative disease (Disease Ontology:DOID:1289); schizophrenia (Disease Ontology:DOID:5419); type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": " (sce:YER148W); (R-SCE-674695); (R-SCE-6807505); (R-SCE-73772); (R-SCE-73776); (R-SCE-73779); (R-SCE-75953); (R-SCE-76042); (R-SCE-76061); (R-SCE-76066); (R-SCE-9018519)", "pathway_count": 11, "publication_count": 20, "publication_id_list": "12093743;12138208;12516863;12660736;17052456;18407956;21126336;24374639;2550146;2673545;2677740;2682626;2690073;33491328;8367480;8413604;8610010;9169868;9618449;9741622", "class_list": "", "function": "General transcription factor that functions at the core of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DM55", "ec_number_list": "", "go_molecular_function": "GO:0008301 DNA binding, bending;GO:0001016 RNA polymerase III transcription regulatory region sequence-specific DNA binding;GO:0003682 chromatin binding;GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0032991 protein-containing complex;GO:0005672 transcription factor TFIIA complex;GO:0005669 transcription factor TFIID complex", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription;GO:0006352 DNA-templated transcription initiation;GO:0070898 RNA polymerase III preinitiation complex assembly;GO:0006359 regulation of transcription by RNA polymerase III", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P13393-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P13433-1", "uniprot_id": "RPOM_YEAST", "mass": 153047.0, "length": 1351, "protein_name": "DNA-directed RNA polymerase, mitochondrial", "gene_name": "RPO41", "organism": "Yeast", "refseq_name": "DNA-directed RNA polymerase", "refseq_ac": "NP_116617", "gene_names_uniprotkb": "RPO41", "gene_names_refseq": "RPO41", "protein_names_uniprotkb": "DNA-directed RNA polymerase, mitochondrial; 2.7.7.6", "protein_names_refseq": "DNA-directed RNA polymerase", "tax_id": 559292, "disease": "combined oxidative phosphorylation deficiency 55 (Disease Ontology:DOID:0070428)", "pathway": " (sce:YFL036W); (R-SCE-163282)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "24374639;3308116;33481703;7670463", "class_list": "", "function": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VTJ4", "ec_number_list": "2.7.7.6;2.1.1.-", "go_molecular_function": "GO:0001018 mitochondrial promoter sequence-specific DNA binding;GO:0003899 DNA-directed RNA polymerase activity", "go_cellular_component": "GO:0034245 mitochondrial DNA-directed RNA polymerase complex;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0042645 mitochondrial nucleoid", "go_biological_process": "GO:0006269 DNA replication, synthesis of primer;GO:0006390 mitochondrial transcription", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P13433-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P13517-1", "uniprot_id": "CAPZB_YEAST", "mass": 32629.0, "length": 287, "protein_name": "F-actin-capping protein subunit beta", "gene_name": "CAP2", "organism": "Yeast", "refseq_name": "F-actin-capping protein subunit beta", "refseq_ac": "NP_012230", "gene_names_uniprotkb": "CAP2", "gene_names_refseq": "CAP2", "protein_names_uniprotkb": "F-actin-capping protein subunit beta", "protein_names_refseq": "F-actin-capping protein subunit beta", "tax_id": 559292, "disease": "dementia (Disease Ontology:DOID:1307); cleft palate (Disease Ontology:DOID:674)", "pathway": " (sce:YIL034C)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "1315784;14562106;17330950;18407956;19779198;19795423;19823750;21126336;2179733;22814378;23749301;24374639;2823100;30516470;32597660;33481703;33491328;38088874;9169870", "class_list": "", "function": "F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVP8;Q07082", "ec_number_list": "", "go_molecular_function": "GO:0051015 actin filament binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0015629 actin cytoskeleton;GO:0008290 F-actin capping protein complex;GO:0030479 actin cortical patch;GO:0000131 incipient cellular bud site", "go_biological_process": "GO:0000902 cell morphogenesis;GO:0030036 actin cytoskeleton organization;GO:0051016 barbed-end actin filament capping;GO:0030447 filamentous growth", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P13517-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P13586-1", "uniprot_id": "ATC1_YEAST", "mass": 104571.0, "length": 950, "protein_name": "Calcium-transporting ATPase 1", "gene_name": "PMR1", "organism": "Yeast", "refseq_name": "Ca(2+)/Mn(2+)-transporting P-type ATPase PMR1", "refseq_ac": "NP_011348", "gene_names_uniprotkb": "PMR1; BSD1; G1666; SCC1", "gene_names_refseq": "BSD1; LDB1; PMR1; SSC1", "protein_names_uniprotkb": "Calcium-transporting ATPase 1; 7.2.2.10; Bypass SOD defects protein 1; Golgi Ca(2+)-ATPase", "protein_names_refseq": "Ca(2+)/Mn(2+)-transporting P-type ATPase PMR1", "tax_id": 559292, "disease": "Hailey-Hailey disease (Disease Ontology:DOID:0050429)", "pathway": " (sce:YGL167C); (R-SCE-936837)", "pathway_count": 2, "publication_count": 16, "publication_id_list": "1325384;14562106;16847258;19779198;19795423;19823750;22218487;22814378;23749301;24374639;2526682;33481703;33491328;38179648;8896267;9169869", "class_list": "", "function": "This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Has a role in the secretory pathway., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTY5", "ec_number_list": "7.2.2.10", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0005509 calcium ion binding;GO:0005388 P-type calcium transporter activity;GO:0140613 P-type manganese transporter activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane", "go_biological_process": "GO:0006816 calcium ion transport;GO:0006874 intracellular calcium ion homeostasis;GO:0016236 macroautophagy;GO:0070588 calcium ion transmembrane transport;GO:0006828 manganese ion transport", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P13586-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P13587-1", "uniprot_id": "ATN1_YEAST", "mass": 120357.0, "length": 1091, "protein_name": "Sodium/potassium exporting P-type ATPase 1", "gene_name": "ENA1", "organism": "Yeast", "refseq_name": "Na(+)/Li(+)-exporting P-type ATPase ENA1", "refseq_ac": "NP_010325", "gene_names_uniprotkb": "ENA1; HOR6; PMR2A; PMR2; YD6888.02C", "gene_names_refseq": "ENA1; HOR6; PMR2", "protein_names_uniprotkb": "Sodium/potassium exporting P-type ATPase 1; 7.2.2.3", "protein_names_refseq": "Na(+)/Li(+)-exporting P-type ATPase ENA1", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR040C)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "14562095;14562106;14617094;16847258;17287358;19915539;2046655;22329368;24374639;2526682;2903861;32597660;32694166;33491328;7664728;8612770;9169867;9315618", "class_list": "", "function": "Catalyzes the hydrolysis of ATP coupled with the export of sodium and potassium from the cell (PubMed:14617094, PubMed:22329368, PubMed:7664728, PubMed:9315618). May export potassium less efficiently (PubMed:14617094). May transport other cations such as lithium (PubMed:7664728, PubMed:9315618). Sodium/potassium efflux ATPases are involved in salt tolerance and maintaining the membrane potential across the plasma membrane in high salinity (Na+) or alkaline (K+) environments (PubMed:22329368, PubMed:7664728, PubMed:9315618). Is negatively modulated by SIS2/HAL3 (PubMed:19915539)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS28", "ec_number_list": "7.2.2.3", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0008554 P-type sodium transporter activity;GO:0016887 ATP hydrolysis activity;GO:0008556 P-type potassium transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0055085 transmembrane transport;GO:0006874 intracellular calcium ion homeostasis;GO:0034220 monoatomic ion transmembrane transport;GO:0006813 potassium ion transport;GO:0009268 response to pH", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P13587-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P13663-1", "uniprot_id": "DHAS_YEAST", "mass": 39544.0, "length": 365, "protein_name": "Aspartate-semialdehyde dehydrogenase", "gene_name": "HOM2", "organism": "Yeast", "refseq_name": "aspartate-semialdehyde dehydrogenase", "refseq_ac": "NP_010442", "gene_names_uniprotkb": "HOM2; YD8358.12", "gene_names_refseq": "HOM2; THR2", "protein_names_uniprotkb": "Aspartate-semialdehyde dehydrogenase; 1.2.1.11; ASA dehydrogenase; ASADH; Aspartate-beta-semialdehyde dehydrogenase", "protein_names_refseq": "aspartate-semialdehyde dehydrogenase", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR158W)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "14562095;14562106;17322287;17330950;17563356;18407956;19684113;19779198;20702584;21126336;21177495;22814378;23749301;24374639;2570346;32597660;33481703;33491328;4145650;9169867", "class_list": "", "function": "Catalyzes the NADPH-dependent formation of L-aspartate 4-semialdehyde (L-ASA) by the reductive dephosphorylation of 4-phospho-L-aspartate (PubMed:4145650). Mediates the second step in the biosynthesis of amino acids that derive from aspartate (the aspartate family of amino acids), including methioinine and threonine, the latter of which is a precursor to isoleucine (PubMed:4145650)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSD8", "ec_number_list": "1.2.1.11", "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0051287 NAD binding;GO:0050661 NADP binding;GO:0004073 aspartate-semialdehyde dehydrogenase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0009086 methionine biosynthetic process;GO:0009088 threonine biosynthetic process;GO:0009090 homoserine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P13663-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P13712-1", "uniprot_id": "MSI1_YEAST", "mass": 47365.0, "length": 422, "protein_name": "Histone-binding protein MSI1", "gene_name": "MSI1", "organism": "Yeast", "refseq_name": "Msi1p", "refseq_ac": "NP_009754", "gene_names_uniprotkb": "MSI1; CAC3; YBR1405", "gene_names_refseq": "CAC3; MSI1", "protein_names_uniprotkb": "Histone-binding protein MSI1; CAF-1 p50 subunit; CAF-1 subunit C; Chromatin assembly factor 1 subunit C; Chromatin assembly factor 1 subunit p50; IRA1 multicopy suppressor", "protein_names_refseq": "Msi1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR195C); (R-SCE-3214815)", "pathway_count": 2, "publication_count": 13, "publication_id_list": "11238915;14562106;17322287;18407956;19683497;23749301;24374639;2554329;33481703;33491328;7813418;8346681;9030687", "class_list": "", "function": "Acts as a component of the histone chaperone complex chromatin assembly factor 1 (CAF-1), which assembles histone octamers onto DNA during replication and repair (PubMed:9030687). CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer (By similarity). Plays a role in the maintenance of heterochromatin (By similarity). Independently, MSI1 is involved in regulation of the RAS/cAMP pathway via sequestration of NPR1 (PubMed:11238915)., [UniProtKB, PubMed, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQI9", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0033186 CAF-1 complex;GO:0070210 Rpd3L-Expanded complex;GO:0033698 Rpd3L complex", "go_biological_process": "GO:0006281 DNA repair;GO:0006338 chromatin remodeling;GO:0006355 regulation of DNA-templated transcription;GO:0006260 DNA replication;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P13712-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P13856-1", "uniprot_id": "RSR1_YEAST", "mass": 30391.0, "length": 272, "protein_name": "Ras-related protein RSR1", "gene_name": "RSR1", "organism": "Yeast", "refseq_name": "Ras family GTPase RSR1", "refseq_ac": "NP_011668", "gene_names_uniprotkb": "RSR1; BUD1; G6658", "gene_names_refseq": "BUD1; RSR1", "protein_names_uniprotkb": "Ras-related protein RSR1; 3.6.5.2", "protein_names_refseq": "Ras family GTPase RSR1", "tax_id": 559292, "disease": "thrombocytopenia (Disease Ontology:DOID:1588)", "pathway": " (sce:YGR152C); (R-SCE-354192); (R-SCE-381676); (R-SCE-392517); (R-SCE-6798695)", "pathway_count": 5, "publication_count": 15, "publication_id_list": "18407956;1910037;19684113;19795423;19823750;23749301;24374639;2690082;29897761;32597660;33481703;33491328;34965436;8585325;9169869", "class_list": "", "function": "Ras-related protein which binds GDP/GTP and possesses intrinsic GTPase activity (PubMed:1910037). Involved in development of cell polarity during the cell division cycle, and essential for bud emergence (PubMed:2690082)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUT2", "ec_number_list": "3.6.5.2;3.6.5.3;3.6.5.-;3.6.5.4;3.1.3.48;3.6.5.5;2.3.1.51;2.3.1.23;2.3.1.n7;3.1.4.4;7.6.2.1;1.2.1.3;1.2.1.64", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:0005774 vacuolar membrane;GO:0030427 site of polarized growth", "go_biological_process": "GO:0032507 maintenance of protein location in cell;GO:0007264 small GTPase-mediated signal transduction;GO:0045184 establishment of protein localization;GO:0035025 positive regulation of Rho protein signal transduction;GO:2000114 regulation of establishment of cell polarity", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P13856-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P14020-1", "uniprot_id": "DPM1_YEAST", "mass": 30362.0, "length": 267, "protein_name": "Dolichol-phosphate mannosyltransferase", "gene_name": "DPM1", "organism": "Yeast", "refseq_name": "dolichyl-phosphate beta-D-mannosyltransferase", "refseq_ac": "NP_015509", "gene_names_uniprotkb": "DPM1; P9705.3; SED3", "gene_names_refseq": "DPM1; SED3", "protein_names_uniprotkb": "Dolichol-phosphate mannosyltransferase; 2.4.1.83; DPM synthase; Dolichol-phosphate mannose synthase; Dolichyl-phosphate beta-D-mannosyltransferase; MPD synthase; Mannose-P-dolichol synthase", "protein_names_refseq": "dolichyl-phosphate beta-D-mannosyltransferase", "tax_id": 559292, "disease": "congenital disorder of glycosylation type I (Disease Ontology:DOID:0050570); congenital disorder of glycosylation Ie (Disease Ontology:DOID:0080557); breast cancer (Disease Ontology:DOID:1612)", "pathway": " (sce:YPR183W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "14562095;14562106;15548536;15657391;24374639;3053713;32597660;33481703;33491328;35028934;9169875", "class_list": "", "function": "Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W4I3", "ec_number_list": "2.4.1.83", "go_molecular_function": "GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0006488 dolichol-linked oligosaccharide biosynthetic process;GO:0035269 protein O-linked glycosylation via mannose;GO:0006506 GPI anchor biosynthetic process;GO:0180047 dolichol phosphate mannose biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P14020-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P14064-1", "uniprot_id": "HAP4_YEAST", "mass": 62412.0, "length": 554, "protein_name": "Transcriptional activator HAP4", "gene_name": "HAP4", "organism": "Yeast", "refseq_name": "transcription factor HAP4", "refseq_ac": "NP_012813", "gene_names_uniprotkb": "HAP4; YKL465", "gene_names_refseq": "HAP4", "protein_names_uniprotkb": "Transcriptional activator HAP4", "protein_names_refseq": "transcription factor HAP4", "tax_id": 559292, "disease": "", "pathway": " (sce:YKL109W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "15075264;16278450;19779198;21177495;23749301;24374639;2676721;33491328;8109175;8196765;9372932", "class_list": "", "function": "Acts a component of the CCAT-binding factor, which is a transcriptional activator and binds to the upstream activation site (UAS2) of the CYC1 gene and other genes involved in mitochondrial electron transport and activates their expression. Recognizes the sequence 5'-CCAAT-3'. HAP4 encodes a regulatory subunit of the DNA-bound complex and seems to provide the principal transcriptional activation domains. Does not bind DNA directly, but augments the binding of HAP2 and HAP3., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXH8", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003713 transcription coactivator activity;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0016602 CCAAT-binding factor complex;GO:0098803 respiratory chain complex", "go_biological_process": "GO:0043457 regulation of cellular respiration;GO:0006109 regulation of carbohydrate metabolic process;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P14064-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P14065-1", "uniprot_id": "GCY1_YEAST", "mass": 35079.0, "length": 312, "protein_name": "Glycerol 2-dehydrogenase (NADP(+))", "gene_name": "GCY1", "organism": "Yeast", "refseq_name": "glycerol 2-dehydrogenase (NADP(+)) GCY1", "refseq_ac": "NP_014763", "gene_names_uniprotkb": "GCY1; GCY; O31567; YOR3269W", "gene_names_refseq": "GCY1", "protein_names_uniprotkb": "Glycerol 2-dehydrogenase (NADP(+)); 1.1.1.156; Galactose-inducible crystallin-like protein 1", "protein_names_refseq": "glycerol 2-dehydrogenase (NADP(+)) GCY1", "tax_id": 559292, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); ductal carcinoma in situ (Disease Ontology:DOID:0060074); B-lymphoblastic leukemia/lymphoma (Disease Ontology:DOID:0080630); castration-resistant prostate carcinoma (Disease Ontology:DOID:0080909); congenital bile acid synthesis defect 2 (Disease Ontology:DOID:0111069); 46,XY sex reversal 8 (Disease Ontology:DOID:0111773); prostate cancer (Disease Ontology:DOID:10283); stomach cancer (Disease Ontology:DOID:10534); pre-eclampsia (Disease Ontology:DOID:10591); polycystic ovary syndrome (Disease Ontology:DOID:11612); allergic disease (Disease Ontology:DOID:1205); leukemia (Disease Ontology:DOID:1240); breast cancer (Disease Ontology:DOID:1612); arteriosclerosis (Disease Ontology:DOID:2349); lung adenocarcinoma (Disease Ontology:DOID:3910); hyperglycemia (Disease Ontology:DOID:4195); hypokalemia (Disease Ontology:DOID:4500); T-cell acute lymphoblastic leukemia (Disease Ontology:DOID:5603); hepatocellular carcinoma (Disease Ontology:DOID:684); cataract (Disease Ontology:DOID:83); diabetic retinopathy (Disease Ontology:DOID:8947); type 2 diabetes mellitus (Disease Ontology:DOID:9352); diabetic neuropathy (Disease Ontology:DOID:9743); galactosemia (Disease Ontology:DOID:9870); obesity (Disease Ontology:DOID:9970)", "pathway": " (sce:YOR120W); (R-SCE-193144); (R-SCE-193368); (R-SCE-193775); (R-SCE-193807); (R-SCE-196108); (R-SCE-2162123); (R-SCE-5365859); (R-SCE-5652227); (R-SCE-70221); (R-SCE-9757110)", "pathway_count": 11, "publication_count": 23, "publication_id_list": "10818358;11113971;11306085;12536147;15127164;17140678;18407956;19779198;20844764;2199324;22842922;22979944;23770562;23896974;24374639;2901985;33491328;8904341;9038161;9169874;9200815;9395503;9435793", "class_list": "", "function": "Glycerol dehydrogenase involved in glycerol catabolism under microaerobic conditions. Has mRNA binding activity., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 25, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2H9", "ec_number_list": "1.1.1.156;1.1.1.117;1.-.-.-;1.2.1.-;1.1.1.2", "go_molecular_function": "GO:0003729 mRNA binding;GO:0004032 aldose reductase (NADPH) activity;GO:0016491 oxidoreductase activity;GO:0008106 alcohol dehydrogenase (NADP+) activity;GO:0047953 glycerol 2-dehydrogenase (NADP+) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0034599 cellular response to oxidative stress;GO:0042843 D-xylose catabolic process;GO:0019568 arabinose catabolic process;GO:0061610 glycerol to glycerone phosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P14065-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P14120-1", "uniprot_id": "RL30_YEAST", "mass": 11415.0, "length": 105, "protein_name": "Large ribosomal subunit protein eL30", "gene_name": "RPL30", "organism": "Yeast", "refseq_name": "60S ribosomal protein eL30 RPL30", "refseq_ac": "NP_011485", "gene_names_uniprotkb": "RPL30; RPL32", "gene_names_refseq": "RPL30", "protein_names_uniprotkb": "Large ribosomal subunit protein eL30; 60S ribosomal protein L30; L32; RP73; YL38", "protein_names_refseq": "60S ribosomal protein eL30 RPL30", "tax_id": 559292, "disease": "cancer (Disease Ontology:DOID:162); herpes simplex (Disease Ontology:DOID:8566)", "pathway": " (sce:YGL030W); (R-SCE-156827); (R-SCE-1799339); (R-SCE-72689); (R-SCE-72706); (R-SCE-975956); (R-SCE-975957); (R-SCE-9954709); (R-SCE-9954714)", "pathway_count": 9, "publication_count": 19, "publication_id_list": "10581556;10601260;12589748;14562106;15242593;18407956;21109664;21126336;22096102;22106047;23749301;24374639;24524803;32597660;3316213;33481703;33491328;9169869;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUA8", "ec_number_list": "", "go_molecular_function": "GO:0030627 pre-mRNA 5'-splice site binding;GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0048025 negative regulation of mRNA splicing, via spliceosome;GO:0006364 rRNA processing;GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P14120-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P14126-1", "uniprot_id": "RL3_YEAST", "mass": 43758.0, "length": 387, "protein_name": "Large ribosomal subunit protein uL3", "gene_name": "RPL3", "organism": "Yeast", "refseq_name": "60S ribosomal protein uL3 RPL3", "refseq_ac": "NP_014706", "gene_names_uniprotkb": "RPL3; MAK8; TCM1; YOR29-14", "gene_names_refseq": "MAK8; RPL3; TCM1; YOR29-14", "protein_names_uniprotkb": "Large ribosomal subunit protein uL3; 60S ribosomal protein L3; Maintenance of killer protein 8; RP1; Trichodermin resistance protein; YL1", "protein_names_refseq": "60S ribosomal protein uL3 RPL3", "tax_id": 559292, "disease": "Shwachman-Diamond syndrome (Disease Ontology:DOID:0060479); dilated cardiomyopathy 2D (Disease Ontology:DOID:0081160)", "pathway": " (sce:YOR063W); (R-SCE-156827); (R-SCE-1799339); (R-SCE-72689); (R-SCE-72706); (R-SCE-975956); (R-SCE-975957); (R-SCE-9954709); (R-SCE-9954714)", "pathway_count": 9, "publication_count": 32, "publication_id_list": "11701127;11875433;14562095;14562106;14976550;1544921;17287358;17330950;17563356;18407956;19779198;19795423;19823750;20702584;20864530;21109664;22096102;22106047;22218487;23749301;24374639;24524803;24865971;26826131;32597660;33481703;33491328;6305925;6355773;9133743;9169874;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:22096102, PubMed:24865971). The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules (PubMed:22096102). The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain (PubMed:22096102). The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (PubMed:22096102). uL3 plays a role in coordinating processes of accommodating the aminoacyl-tRNA in the PTC (PubMed:22096102)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 29, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2C6;Q08459", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0006412 translation;GO:0006364 rRNA processing;GO:1990145 maintenance of translational fidelity;GO:0006414 translational elongation;GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 3.3, "record_id": "P14126-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P14164-1", "uniprot_id": "ABF1_YEAST", "mass": 81753.0, "length": 731, "protein_name": "ARS-binding factor 1", "gene_name": "ABF1", "organism": "Yeast", "refseq_name": "DNA-binding protein ABF1", "refseq_ac": "NP_012810", "gene_names_uniprotkb": "ABF1; BAF1; OBF1; REB2; SBF1; YKL505", "gene_names_refseq": "ABF1; BAF1; EBF2; OBF1; REB2; SBF1", "protein_names_uniprotkb": "ARS-binding factor 1; Bidirectionally acting factor 1; DNA replication enhancer-binding protein OBF1; SFB-B", "protein_names_refseq": "DNA-binding protein ABF1", "tax_id": 559292, "disease": "", "pathway": " (sce:YKL112W)", "pathway_count": 1, "publication_count": 45, "publication_id_list": "10601031;10684934;11713306;11756546;11875433;12200417;14562106;15177043;15456886;15522095;1561835;16083878;16908533;17158163;17330950;17563356;18305101;18407956;18996839;19130580;19779198;19795423;19823750;20098497;2034654;20702584;21081559;21126336;21177495;22106047;22218487;23749301;24374639;24909858;2511628;2620828;2686983;32597660;33481703;33491328;33502312;7608180;8065362;8196765;9430660", "class_list": "", "function": "General regulatory factor (GRF) that contributes to transcriptional activation of a large number of genes, as well as to DNA replication, silencing and telomere structure. Involved in the transcription activation of a subset of ribosomal protein genes. Binds the ARS-elements found in many promoters. Binds to the sequence 5'-TCN(7)ACG-3'. Influences on genome-wide nucleosome occupancy and affects chromatin structure, and probably dynamics. As a component of the global genome repair (GGR) complex, promotes global genome nucleotide excision repair (GG-NER) which removes DNA damage from nontranscribing DNA. Component of the regulatory network controlling mitotic and meiotic cell cycle progression., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 39, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXH6", "ec_number_list": "", "go_molecular_function": "GO:0003688 DNA replication origin binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0043565 sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0044374 sequence-specific DNA binding, bending", "go_cellular_component": "GO:0005634 nucleus;GO:0000113 nucleotide-excision repair factor 4 complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0070911 global genome nucleotide-excision repair", "synthesized_glycan_count": 0, "hit_score": 4.6, "record_id": "P14164-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P14180-1", "uniprot_id": "CHS2_YEAST", "mass": 109882.0, "length": 963, "protein_name": "Chitin synthase 2", "gene_name": "CHS2", "organism": "Yeast", "refseq_name": "chitin synthase CHS2", "refseq_ac": "NP_009594", "gene_names_uniprotkb": "CHS2; YBR0407", "gene_names_refseq": "CHS2", "protein_names_uniprotkb": "Chitin synthase 2; 2.4.1.16; Chitin-UDP acetyl-glucosaminyl transferase 2", "protein_names_refseq": "chitin synthase CHS2", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR038W)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "11875433;16847258;17287358;17563356;18407956;19684113;19779198;20702584;21177495;22573892;23468521;23749301;24374639;2533436;32597660;33481703;33491328;35230542;7775457;7813418", "class_list": "", "function": "Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer (Probable). Required for septum formation (Probable)., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 35, "reported_mutagensis": 49, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VQ38", "ec_number_list": "2.4.1.16", "go_molecular_function": "GO:0004100 chitin synthase activity", "go_cellular_component": "GO:0016020 membrane;GO:0071944 cell periphery;GO:0030428 cell septum;GO:0005935 cellular bud neck", "go_biological_process": "GO:0006031 chitin biosynthetic process;GO:0071555 cell wall organization;GO:1902404 mitotic actomyosin contractile ring contraction", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P14180-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P14242-1", "uniprot_id": "PMS1_YEAST", "mass": 99355.0, "length": 873, "protein_name": "DNA mismatch repair protein PMS1", "gene_name": "PMS1", "organism": "Yeast", "refseq_name": "ATP-binding mismatch repair protein", "refseq_ac": "NP_014317", "gene_names_uniprotkb": "PMS1; N2317", "gene_names_refseq": "PMS1", "protein_names_uniprotkb": "DNA mismatch repair protein PMS1; Postmeiotic segregation protein 1", "protein_names_refseq": "ATP-binding mismatch repair protein", "tax_id": 559292, "disease": "hereditary nonpolyposis colorectal cancer type 4 (Disease Ontology:DOID:0070275); mismatch repair cancer syndrome (Disease Ontology:DOID:0112182); prostate cancer (Disease Ontology:DOID:10283); urinary bladder cancer (Disease Ontology:DOID:11054); breast cancer (Disease Ontology:DOID:1612); ovarian cancer (Disease Ontology:DOID:2394); Lynch syndrome (Disease Ontology:DOID:3883)", "pathway": " (sce:YNL082W); (R-SCE-5358565)", "pathway_count": 2, "publication_count": 27, "publication_id_list": "10570173;10938116;11717305;11907579;12222686;12682353;12748633;14562095;14562106;16227575;16273108;16492773;17563356;18407956;19779198;20702584;23749301;24374639;2676974;32597660;33481703;33491328;8701611;8740422;9169873;9234704;9545323", "class_list": "", "function": "Required for DNA mismatch repair (MMR), correcting base-base mismatches and insertion-deletion loops (IDLs) resulting from DNA replication, DNA damage or from recombination events between non-identical sequences during meiosis. Component of the MutLalpha heterodimer that forms a ternary complex with the MutS heterodimers, which initially recognize the DNA mismatches. This complex is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. Plays a major role in maintaining the genetic stability of simple sequence repeats and in the repair of heteroduplex sites present in meiotic recombination intermediates., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 18, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W197;Q2I044;Q2I045;Q45TY4;Q8TG48;Q8TG50;Q8TG54;Q8TG57", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0030983 mismatched DNA binding;GO:0140664 ATP-dependent DNA damage sensor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0032389 MutLalpha complex", "go_biological_process": "GO:0000710 meiotic mismatch repair;GO:0006298 mismatch repair", "synthesized_glycan_count": 0, "hit_score": 2.8, "record_id": "P14242-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P14291-1", "uniprot_id": "RED1_YEAST", "mass": 95538.0, "length": 827, "protein_name": "Protein RED1", "gene_name": "RED1", "organism": "Yeast", "refseq_name": "Red1p", "refseq_ac": "NP_013365", "gene_names_uniprotkb": "RED1; L8479.6", "gene_names_refseq": "RED1", "protein_names_uniprotkb": "Protein RED1; Reductional division protein 1", "protein_names_refseq": "Red1p", "tax_id": 559292, "disease": "male infertility (Disease Ontology:DOID:12336)", "pathway": " (sce:YLR263W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "21173162;24374639;2550770;33502312;9169871", "class_list": "", "function": "Probable constituent of the synaptonemal complex during meiosis. May interact with HOP1. Required for meiosis I chromosome segregation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYR0", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0005198 structural molecule activity;GO:0031490 chromatin DNA binding", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0000800 lateral element;GO:0000795 synaptonemal complex", "go_biological_process": "GO:0051598 meiotic recombination checkpoint signaling;GO:0007130 synaptonemal complex assembly;GO:0007129 homologous chromosome pairing at meiosis;GO:0007131 reciprocal meiotic recombination;GO:0035825 homologous recombination", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P14291-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P14306-1", "uniprot_id": "CPYI_YEAST", "mass": 24357.0, "length": 219, "protein_name": "Carboxypeptidase Y inhibitor", "gene_name": "TFS1", "organism": "Yeast", "refseq_name": "Tfs1p", "refseq_ac": "NP_013279", "gene_names_uniprotkb": "TFS1; DKA1; L9470.19; NSP1", "gene_names_refseq": "DKA1; NSP1; TFS1", "protein_names_uniprotkb": "Carboxypeptidase Y inhibitor; CDC25 suppressor 1; CPY inhibitor; I(C); Ic; Protein DKA1; Protein NSP1", "protein_names_refseq": "Tfs1p", "tax_id": 559292, "disease": "prostate cancer (Disease Ontology:DOID:10283); Alzheimer's disease (Disease Ontology:DOID:10652); ovarian cancer (Disease Ontology:DOID:2394); myocardial infarction (Disease Ontology:DOID:5844)", "pathway": " (sce:YLR178C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "12459491;12473200;14562106;1745232;18407956;24374639;2693892;33491328;9169871;9521655", "class_list": "", "function": "Specific and potent inhibitor of carboxypeptidase Y., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYI2;P30312", "ec_number_list": "", "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity;GO:0005543 phospholipid binding;GO:0030414 peptidase inhibitor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0000329 fungal-type vacuole membrane;GO:0000328 fungal-type vacuole lumen", "go_biological_process": "GO:0030162 regulation of proteolysis;GO:0046578 regulation of Ras protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P14306-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P14540-1", "uniprot_id": "ALF_YEAST", "mass": 39621.0, "length": 359, "protein_name": "Fructose-bisphosphate aldolase", "gene_name": "FBA1", "organism": "Yeast", "refseq_name": "fructose-bisphosphate aldolase FBA1", "refseq_ac": "NP_012863", "gene_names_uniprotkb": "FBA1; YKL320", "gene_names_refseq": "FBA1; LOT1", "protein_names_uniprotkb": "Fructose-bisphosphate aldolase; 4.1.2.13; FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase", "protein_names_refseq": "fructose-bisphosphate aldolase FBA1", "tax_id": 559292, "disease": "", "pathway": " (sce:YKL060C)", "pathway_count": 1, "publication_count": 27, "publication_id_list": "14562106;1698168;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22106047;22218487;22814378;23749301;24374639;24909858;2647491;32597660;33481703;33491328;7895733;8091862;8196765;8935650", "class_list": "", "function": "Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 37, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXM7", "ec_number_list": "4.1.2.13", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004332 fructose-bisphosphate aldolase activity;GO:1904408 melatonin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0006094 gluconeogenesis;GO:0006096 glycolytic process;GO:0061621 canonical glycolysis", "synthesized_glycan_count": 0, "hit_score": 2.8, "record_id": "P14540-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P14680-1", "uniprot_id": "YAK1_YEAST", "mass": 91245.0, "length": 807, "protein_name": "Dual specificity protein kinase YAK1", "gene_name": "YAK1", "organism": "Yeast", "refseq_name": "serine/threonine protein kinase YAK1", "refseq_ac": "NP_012394", "gene_names_uniprotkb": "YAK1; J0652", "gene_names_refseq": "YAK1", "protein_names_uniprotkb": "Dual specificity protein kinase YAK1; 2.7.12.1", "protein_names_refseq": "serine/threonine protein kinase YAK1", "tax_id": 559292, "disease": "Parkinson's disease (Disease Ontology:DOID:14330); depressive disorder (Disease Ontology:DOID:1596); cancer (Disease Ontology:DOID:162)", "pathway": " (sce:YJL141C); (R-SCE-3899300)", "pathway_count": 2, "publication_count": 27, "publication_id_list": "10816418;11358866;11875433;12141686;15665377;17287358;17330950;18407956;19684113;19779198;19795423;19823750;20489023;20702584;21126336;21177495;21255108;23749301;24374639;2558053;30516470;32597660;33229814;33481703;33491328;8641269;8813765", "class_list": "", "function": "Negative regulator of the cell cycle acting downstream of the cAMP-dependent protein kinase. Part of a glucose-sensing system involved in growth control in response to glucose availability. Phosphorylates POP2., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 6, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 6, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 6, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 29, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 3, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "D6VW43", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;2.3.2.-;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0004712 protein serine/threonine/tyrosine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0045893 positive regulation of DNA-templated transcription;GO:0010811 positive regulation of cell-substrate adhesion;GO:0141156 cAMP/PKA signal transduction", "synthesized_glycan_count": 0, "hit_score": 3.5, "record_id": "P14680-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P14682-1", "uniprot_id": "UBC3_YEAST", "mass": 34065.0, "length": 295, "protein_name": "Ubiquitin-conjugating enzyme E2-34 kDa", "gene_name": "CDC34", "organism": "Yeast", "refseq_name": "SCF E2 ubiquitin-protein ligase catalytic subunit CDC34", "refseq_ac": "NP_010339", "gene_names_uniprotkb": "CDC34; D4211; DNA6; UBC3; YD9609.08C", "gene_names_refseq": "CDC34; DNA6; UBC3", "protein_names_uniprotkb": "Ubiquitin-conjugating enzyme E2-34 kDa; 2.3.2.23; Cell division control protein 34; E2 ubiquitin-conjugating enzyme 3; E3 ubiquitin ligase complex SCF subunit CDC34; Ubiquitin carrier protein; Ubiquitin-protein ligase", "protein_names_refseq": "SCF E2 ubiquitin-protein ligase catalytic subunit CDC34", "tax_id": 559292, "disease": "azoospermia (Disease Ontology:DOID:14227); congenital heart disease (Disease Ontology:DOID:1682)", "pathway": " (sce:YDR054C); (R-SCE-983168)", "pathway_count": 2, "publication_count": 23, "publication_id_list": "10385629;14562095;14562106;16952051;17461777;18407956;18418079;19779198;21126336;21177495;21453497;21637798;22218487;23749301;24374639;2842867;32597660;33481703;33491328;8789263;9169867;9312054;9499404", "class_list": "", "function": "Catalyzes the covalent attachment of ubiquitin to other proteins. Capable, in vitro, to ubiquitinate histone H2A., [UniProtKB]; Mediates the initiation of DNA replication (transition of G1 to S phase in cell cycle). Essential component of the E3 ubiquitin ligase complex SCF (SKP1-CUL1-F-box protein), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the regulation of methionine biosynthesis genes and in the degradation of CDC6 together with CDC4 and CDC53., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 29, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS40", "ec_number_list": "2.3.2.23;2.3.2.27;6.2.1.45;2.3.2.-;2.3.2.26;2.3.2.31;1.14.11.27;2.3.2.34;6.3.2.-", "go_molecular_function": "GO:0005524 ATP binding;GO:0004842 ubiquitin-protein transferase activity;GO:0061631 ubiquitin conjugating enzyme activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0019005 SCF ubiquitin ligase complex;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0031509 subtelomeric heterochromatin formation;GO:0051301 cell division;GO:0000086 G2/M transition of mitotic cell cycle;GO:0006260 DNA replication;GO:0007346 regulation of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P14682-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P14693-1", "uniprot_id": "SAM35_YEAST", "mass": 37404.0, "length": 329, "protein_name": "Sorting assembly machinery 35 kDa subunit", "gene_name": "SAM35", "organism": "Yeast", "refseq_name": "SAM complex subunit SAM35", "refseq_ac": "NP_011951", "gene_names_uniprotkb": "SAM35; OMP85; TOB38; TOM38", "gene_names_refseq": "FMP20; SAM35; TOB38; TOM38", "protein_names_uniprotkb": "Sorting assembly machinery 35 kDa subunit; Mitochondrial 38 kDa outer membrane protein; TOB complex 38 kDa subunit", "protein_names_refseq": "SAM complex subunit SAM35", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR083W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "14562106;14699090;15067005;15205677;15326197;19795423;19823750;21126336;24374639;2558054;33491328;8091229", "class_list": "", "function": "Essential component of the mitochondrial outer membrane sorting assembly machinery (SAM or TOB) complex, which is required for the sorting of proteins with complicated topology, such as beta-barrel proteins, to the mitochondrial outer membrane after import by the TOM complex., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DL34", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0001401 SAM complex;GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0045040 protein insertion into mitochondrial outer membrane;GO:0030150 protein import into mitochondrial matrix;GO:0070096 mitochondrial outer membrane translocase complex assembly", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P14693-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P14724-1", "uniprot_id": "CDC26_YEAST", "mass": 14081.0, "length": 124, "protein_name": "Anaphase-promoting complex subunit CDC26", "gene_name": "CDC26", "organism": "Yeast", "refseq_name": "anaphase promoting complex subunit CDC26", "refseq_ac": "NP_116694", "gene_names_uniprotkb": "CDC26; HIT3; SCD26", "gene_names_refseq": "CDC26; HIT3; SCD26", "protein_names_uniprotkb": "Anaphase-promoting complex subunit CDC26; Cell division control protein 26", "protein_names_refseq": "anaphase promoting complex subunit CDC26", "tax_id": 559292, "disease": "", "pathway": " (sce:YFR036W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "14562095;15060174;17322287;1736102;19779198;24374639;2690018;33481703;33491328;7670463;8686381;8895471", "class_list": "", "function": "Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome. In early mitosis, the APC/C is activated by CDC20 and targets securin PDS1, the B-type cyclin CLB5, and other anaphase inhibitory proteins for proteolysis, thereby triggering the separation of sister chromatids at the metaphase-to-anaphase transition. In late mitosis and in G1, degradation of CLB5 allows activation of the APC/C by CDH1, which is needed to destroy CDC20 and the B-type cyclin CLB2 to allow exit from mitosis and creating the low CDK state necessary for cytokinesis and for reforming prereplicative complexes in G1 prior to another round of replication., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTR9", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005680 anaphase-promoting complex", "go_biological_process": "GO:0051301 cell division;GO:0007346 regulation of mitotic cell cycle;GO:0016567 protein ubiquitination;GO:0006325 chromatin organization;GO:0031145 anaphase-promoting complex-dependent catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P14724-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P14736-1", "uniprot_id": "RAD4_YEAST", "mass": 87174.0, "length": 754, "protein_name": "DNA repair protein RAD4", "gene_name": "RAD4", "organism": "Yeast", "refseq_name": "Rad4p", "refseq_ac": "NP_011089", "gene_names_uniprotkb": "RAD4", "gene_names_refseq": "RAD4", "protein_names_uniprotkb": "DNA repair protein RAD4", "protein_names_refseq": "Rad4p", "tax_id": 559292, "disease": "xeroderma pigmentosum (Disease Ontology:DOID:0050427); xeroderma pigmentosum group C (Disease Ontology:DOID:0110844); lung cancer (Disease Ontology:DOID:1324); pancreatic cancer (Disease Ontology:DOID:1793); serous cystadenocarcinoma (Disease Ontology:DOID:3114)", "pathway": " (sce:YER162C); (R-SCE-3108214)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "14562095;14562106;22814378;24374639;2649477;3073107;33481703;33491328;9169868", "class_list": "", "function": "Involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DM70", "ec_number_list": "", "go_molecular_function": "GO:0003684 damaged DNA binding;GO:0003697 single-stranded DNA binding;GO:1990165 single-strand break-containing DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0071942 XPC complex;GO:0000111 nucleotide-excision repair factor 2 complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006298 mismatch repair;GO:0000715 nucleotide-excision repair, DNA damage recognition;GO:0006265 DNA topological change", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P14736-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P14737-1", "uniprot_id": "RAD9_YEAST", "mass": 148398.0, "length": 1309, "protein_name": "DNA repair protein RAD9", "gene_name": "RAD9", "organism": "Yeast", "refseq_name": "chromatin-binding protein RAD9", "refseq_ac": "NP_010503", "gene_names_uniprotkb": "RAD9; YD9934.02C", "gene_names_refseq": "RAD9", "protein_names_uniprotkb": "DNA repair protein RAD9", "protein_names_refseq": "chromatin-binding protein RAD9", "tax_id": 559292, "disease": "pulmonary hypertension (Disease Ontology:DOID:6432)", "pathway": " (sce:YDR217C); (R-SCE-3232118)", "pathway_count": 2, "publication_count": 30, "publication_id_list": "11124038;12049741;14562106;15060150;15972895;17287358;17563356;18407956;19779198;19795423;19823750;20190278;20700441;20702584;21126336;21946560;22218487;2247073;23593009;23749301;24374639;25569305;2664461;27821475;28912563;32597660;33481703;33491328;9169867;9755168", "class_list": "", "function": "Essential for cell cycle arrest at the G2 stage following DNA damage by X-irradiation or inactivation of DNA ligase., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 105, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VSK0;Q04920", "ec_number_list": "", "go_molecular_function": "GO:0008047 enzyme activator activity;GO:0003690 double-stranded DNA binding;GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0090734 site of DNA damage", "go_biological_process": "GO:0006281 DNA repair;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006302 double-strand break repair;GO:0031573 mitotic intra-S DNA damage checkpoint signaling;GO:0000077 DNA damage checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 3.1, "record_id": "P14737-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P14743-1", "uniprot_id": "NMT_YEAST", "mass": 52838.0, "length": 455, "protein_name": "Glycylpeptide N-tetradecanoyltransferase", "gene_name": "NMT1", "organism": "Yeast", "refseq_name": "glycylpeptide N-tetradecanoyltransferase NMT1", "refseq_ac": "NP_013296", "gene_names_uniprotkb": "NMT1; CDC72; L8167.14", "gene_names_refseq": "CDC72; NMT1", "protein_names_uniprotkb": "Glycylpeptide N-tetradecanoyltransferase; 2.3.1.97; Cell division control protein 72; Myristoyl-CoA:protein N-myristoyltransferase; NMT; Peptide N-myristoyltransferase", "protein_names_refseq": "glycylpeptide N-tetradecanoyltransferase NMT1", "tax_id": 559292, "disease": "muscular disease (Disease Ontology:DOID:0080000)", "pathway": " (sce:YLR195C); (R-SCE-2514859)", "pathway_count": 2, "publication_count": 13, "publication_id_list": "11371195;11478885;14562095;2045414;24374639;2644694;3106975;33491328;8416952;8430078;8955162;9169871;9846880", "class_list": "", "function": "Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins. Substrate specificity requires an N-terminal glycine in the nascent polypeptide substrates. Uncharged amino acids are preferred at position 2 while neutral residues are favored at positions 3 and 4. Ser is present at position 5 in almost all known N-myristoyl proteins and Lys is commonly encountered at postion 6., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 12, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYJ8", "ec_number_list": "2.3.1.97", "go_molecular_function": "GO:0004379 glycylpeptide N-tetradecanoyltransferase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0018008 N-terminal peptidyl-glycine N-myristoylation;GO:0072657 protein localization to membrane", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P14743-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P14747-1", "uniprot_id": "PP2B2_YEAST", "mass": 68528.0, "length": 604, "protein_name": "Serine/threonine-protein phosphatase 2B catalytic subunit A2", "gene_name": "CMP2", "organism": "Yeast", "refseq_name": "calcineurin catalytic subunit A", "refseq_ac": "NP_013655", "gene_names_uniprotkb": "CMP2; CNA2; YM9958.05", "gene_names_refseq": "CMP2; CNA2", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase 2B catalytic subunit A2; 3.1.3.16; Calcineurin A2; Calmodulin-binding protein 2", "protein_names_refseq": "calcineurin catalytic subunit A", "tax_id": 559292, "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); developmental and epileptic encephalopathy 91 (Disease Ontology:DOID:0080472); dilated cardiomyopathy (Disease Ontology:DOID:12930); focal segmental glomerulosclerosis (Disease Ontology:DOID:1312); aortic valve stenosis (Disease Ontology:DOID:1712); cholangiocarcinoma (Disease Ontology:DOID:4947); schizophrenia (Disease Ontology:DOID:5419); kidney disease (Disease Ontology:DOID:557)", "pathway": " (sce:YML057W)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "14562106;1646387;1651503;17563356;18407956;19779198;20489023;21126336;21177495;23749301;24374639;2557079;32597660;33481703;33491328;34965436;9169872", "class_list": "", "function": "Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZB7", "ec_number_list": "3.1.3.16;3.1.3.43;3.1.3.48", "go_molecular_function": "GO:0033192 calmodulin-dependent protein phosphatase activity;GO:0005516 calmodulin binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005955 calcineurin complex", "go_biological_process": "GO:0097720 calcineurin-mediated signaling;GO:0045893 positive regulation of DNA-templated transcription;GO:0022604 regulation of cell morphogenesis;GO:0006873 intracellular monoatomic ion homeostasis;GO:0071444 cellular response to pheromone", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P14747-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P14772-1", "uniprot_id": "BPT1_YEAST", "mass": 176874.0, "length": 1559, "protein_name": "Bile pigment transporter 1", "gene_name": "BPT1", "organism": "Yeast", "refseq_name": "ATP-binding cassette bilirubin transporter BPT1", "refseq_ac": "NP_013086", "gene_names_uniprotkb": "BPT1; L1313", "gene_names_refseq": "BPT1", "protein_names_uniprotkb": "Bile pigment transporter 1", "protein_names_refseq": "ATP-binding cassette bilirubin transporter BPT1", "tax_id": 559292, "disease": "arterial calcification of infancy (Disease Ontology:DOID:0050644); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); primary biliary cholangitis (Disease Ontology:DOID:12236); Dubin-Johnson syndrome (Disease Ontology:DOID:12308); hyperprolactinemia (Disease Ontology:DOID:12700); cholestasis (Disease Ontology:DOID:13580); status epilepticus (Disease Ontology:DOID:1824); epilepsy (Disease Ontology:DOID:1826); pseudoxanthoma elasticum (Disease Ontology:DOID:2738); bilirubin metabolic disorder (Disease Ontology:DOID:2741); coronary artery disease (Disease Ontology:DOID:3393); kidney disease (Disease Ontology:DOID:557); hepatocellular carcinoma (Disease Ontology:DOID:684); end stage renal disease (Disease Ontology:DOID:783); type 2 diabetes mellitus (Disease Ontology:DOID:9352); steatotic liver disease (Disease Ontology:DOID:9452)", "pathway": " (sce:YLL015W); (R-SCE-1660661); (R-SCE-189483); (R-SCE-2142691); (R-SCE-382556); (R-SCE-9707564); (R-SCE-9749641); (R-SCE-9753281); (R-SCE-9754706); (R-SCE-9758890)", "pathway_count": 10, "publication_count": 21, "publication_id_list": "10790694;12044871;15665377;16847258;17287358;17330950;17563356;18407956;19779198;20702584;21126336;23749301;24374639;2545538;32597660;33481703;33491328;34965436;8810043;9046100;9169871", "class_list": "", "function": "Cooperates for the ATP-dependent vacuolar transport of bilirubin and glutathione conjugates., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 18, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 16, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VXY7", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0015086 cadmium ion transmembrane transporter activity;GO:0140359 ABC-type transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0042144 vacuole fusion, non-autophagic;GO:0055085 transmembrane transport;GO:0015691 cadmium ion transport", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P14772-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P14832-1", "uniprot_id": "CYPH_YEAST", "mass": 17391.0, "length": 162, "protein_name": "Peptidyl-prolyl cis-trans isomerase", "gene_name": "CPR1", "organism": "Yeast", "refseq_name": "peptidylprolyl isomerase CPR1", "refseq_ac": "NP_010439", "gene_names_uniprotkb": "CPR1; CPH1; CYP1; SCC1; YD8358.10C", "gene_names_refseq": "CPH1; CPR1; CYP1", "protein_names_uniprotkb": "Peptidyl-prolyl cis-trans isomerase; 5.2.1.8; CPH; Cyclophilin; Cyclosporin A-binding protein; PPI-II; PPIase; Rotamase", "protein_names_refseq": "peptidylprolyl isomerase CPR1", "tax_id": 559292, "disease": "childhood-onset asthma (Disease Ontology:DOID:0080815); Bell's palsy (Disease Ontology:DOID:12506); aggressive periodontitis (Disease Ontology:DOID:1474); epilepsy (Disease Ontology:DOID:1826); cholangiocarcinoma (Disease Ontology:DOID:4947); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); nasopharynx carcinoma (Disease Ontology:DOID:9261)", "pathway": " (sce:YDR155C); (R-SCE-6798695)", "pathway_count": 2, "publication_count": 28, "publication_id_list": "10899127;11641409;11711434;14562106;15643056;16823961;17287358;17322287;17330950;17563356;18407956;19779198;19795423;19823750;21126336;2183184;22106047;22814378;22984289;23749301;24374639;24909858;2687115;32597660;33481703;33491328;8431466;9169867", "class_list": "", "function": "PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in histone deacetylase complexes, suggesting a function in chromatin. Imports fructose-1,6-bisphosphatase (FBPase) into the intermediate vacuole import and degradation (Vid) vesicles. Regulates the meiotic gene program via the Set3C histone deacetylase complex to promote efficient sporulation, and the prolyl-isomerase activity is required for this function., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSD6", "ec_number_list": "2.7.1.40;5.4.2.11;2.7.1.1;4.2.1.24;3.6.4.13;2.4.1.1;3.4.23.25;3.6.4.10;5.3.1.9;5.1.3.-;5.2.1.8;1.11.1.6;3.5.4.6;2.7.1.11;2.7.1.2;1.1.1.42;3.4.25.1;3.6.4.6;3.6.5.-;2.7.11.24;3.6.4.12;5.4.2.2;1.11.1.24;2.7.4.6;2.4.1.186;1.1.1.205;2.7.1.35;3.4.19.12;2.4.2.7;5.4.2.7;2.3.2.26;2.7.11.23;2.4.2.1;2.7.1.59;3.5.4.5;3.4.11.-;3.3.2.10", "go_molecular_function": "GO:0003729 mRNA binding;GO:0016018 cyclosporin A binding;GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005758 mitochondrial intermembrane space;GO:0034967 Set3 complex", "go_biological_process": "GO:0045836 positive regulation of meiotic nuclear division;GO:0015031 protein transport;GO:0006974 DNA damage response;GO:0006457 protein folding;GO:0009267 cellular response to starvation", "synthesized_glycan_count": 0, "hit_score": 2.9, "record_id": "P14832-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P14904-1", "uniprot_id": "AMPL_YEAST", "mass": 57093.0, "length": 514, "protein_name": "Vacuolar aminopeptidase 1", "gene_name": "APE1", "organism": "Yeast", "refseq_name": "metalloaminopeptidase APE1", "refseq_ac": "NP_012819", "gene_names_uniprotkb": "APE1; API; LAP4; YKL455; YSC1", "gene_names_refseq": "APE1; API; LAP4; YSC1", "protein_names_uniprotkb": "Vacuolar aminopeptidase 1; 3.4.11.22; Aminopeptidase yscI; LAPIV; Leucine aminopeptidase IV; Lysosomal aminopeptidase III; Polypeptidase; Vacuolar aminopeptidase I", "protein_names_refseq": "metalloaminopeptidase APE1", "tax_id": 559292, "disease": "", "pathway": " (sce:YKL103C)", "pathway_count": 1, "publication_count": 32, "publication_id_list": "11152450;11382752;11430817;1400574;14562106;15138258;17329814;18407956;19185714;22123825;24374639;24493041;26208681;2651436;2689224;27266708;27320913;33491328;363165;3882418;3890752;3916861;5147;6352682;8109175;8196765;8521804;8601598;8901576;9151668;9214379;9412464", "class_list": "", "function": "Resident vacuolar enzyme that catalyzes the removal of amino acids from the N-terminus of peptides and proteins. Also acts as the major cargo protein of the cytoplasm-to-vacuole targeting (Cvt) pathway. The precursor form of aminopeptidase 1 (prApe1) assembles into dodecamers and the propeptide mediates the aggregation of dodecamers into higher multimers. The multimers are then recognized via the propeptide by their receptor ATG19, and ATG19 further interacts with ATG11, which tethers the APE1-ATG19 complex to the pre-autophagosomal structure (PAS). The cargo-receptor complex (also Cvt complex) is selectively enwrapped by a double-membrane structure termed the Cvt vesicle under vegetative growth conditions and by a similar but larger double-membrane structure termed the autophagosome under nitrogen starvation conditions. The Cvt vesicle or the autophagosome fuses with the vacuolar membrane and release its content in the vacuolar lumen. In the vacuole, prApe1 is processed into mature aminopeptidase 1 (mApe1)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VXI5;P22060", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0070006 metalloaminopeptidase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0000324 fungal-type vacuole;GO:0034270 Cvt complex", "go_biological_process": "GO:0006508 proteolysis;GO:0032258 cytoplasm to vacuole targeting by the Cvt pathway", "synthesized_glycan_count": 0, "hit_score": 3.3, "record_id": "P14904-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P14906-1", "uniprot_id": "SEC63_YEAST", "mass": 75345.0, "length": 663, "protein_name": "Protein translocation protein SEC63", "gene_name": "SEC63", "organism": "Yeast", "refseq_name": "protein-transporting protein SEC63", "refseq_ac": "NP_014897", "gene_names_uniprotkb": "SEC63; NPL1; PTL1", "gene_names_refseq": "PTL1; SEC63", "protein_names_uniprotkb": "Protein translocation protein SEC63; Protein NPL1; Sec62/63 complex 73 kDa subunit", "protein_names_refseq": "protein-transporting protein SEC63", "tax_id": 559292, "disease": "polycystic liver disease (Disease Ontology:DOID:0050770); polycystic liver disease 2 (Disease Ontology:DOID:0060975); steatotic liver disease (Disease Ontology:DOID:9452)", "pathway": " (sce:YOR254C)", "pathway_count": 1, "publication_count": 24, "publication_id_list": "11226176;12518317;14562106;14690591;15671059;1620130;16847258;17287358;17330950;18407956;19779198;2000150;20702584;23749301;24374639;2556404;32597660;33481703;33491328;7758110;8253836;8514125;9153759;9169874", "class_list": "", "function": "Acts as a component of the Sec62/63 complex which is involved in SRP-independent post-translational translocation across the endoplasmic reticulum (ER) and functions together with the Sec61 complex and KAR2 in a channel-forming translocon complex. A cycle of assembly and disassembly of Sec62/63 complex from SEC61 may govern the activity of the translocon. SEC63 may affect SEC1-polypeptide interactions by increasing the affinity of targeting pathways for SEC61 and/or by modifying SEC61 to allow more efficient polypeptide interaction. May also be involved in SRP-dependent cotranslational translocation. Is essential for cell growth and for germination., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2V5;Q08690", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0008320 protein transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005637 nuclear inner membrane;GO:0030867 rough endoplasmic reticulum membrane;GO:0031207 Sec62/Sec63 complex", "go_biological_process": "GO:0006620 post-translational protein targeting to endoplasmic reticulum membrane;GO:0006614 SRP-dependent cotranslational protein targeting to membrane;GO:0031204 post-translational protein targeting to membrane, translocation;GO:0046967 cytosol to endoplasmic reticulum transport", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "P14906-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P14908-1", "uniprot_id": "MTF1_YEAST", "mass": 39727.0, "length": 341, "protein_name": "Mitochondrial transcription factor 1", "gene_name": "MTF1", "organism": "Yeast", "refseq_name": "RNA polymerase specificity factor", "refseq_ac": "NP_013955", "gene_names_uniprotkb": "MTF1; YM9959.10", "gene_names_refseq": "MTF1", "protein_names_uniprotkb": "Mitochondrial transcription factor 1; 2.1.1.-; Mitochondrial transcription factor mtTFB; Mitochondrial-specificity factor; RF1023", "protein_names_refseq": "RNA polymerase specificity factor", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR228W); (R-SCE-163282)", "pathway_count": 2, "publication_count": 12, "publication_id_list": "11567089;14562106;1549466;16823961;1939277;19795423;19823750;22984289;24374639;2853292;8384295;9169872", "class_list": "", "function": "Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with DNA in a non-specific manner., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W053", "ec_number_list": "2.7.7.6;2.1.1.-", "go_molecular_function": "GO:0003677 DNA binding;GO:0003723 RNA binding;GO:0008168 methyltransferase activity;GO:0034246 mitochondrial transcription factor activity", "go_cellular_component": "GO:0034245 mitochondrial DNA-directed RNA polymerase complex;GO:0005739 mitochondrion;GO:0005758 mitochondrial intermembrane space;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006391 transcription initiation at mitochondrial promoter;GO:0032259 methylation;GO:0032786 positive regulation of DNA-templated transcription, elongation;GO:0006390 mitochondrial transcription", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P14908-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P14922-1", "uniprot_id": "CYC8_YEAST", "mass": 107202.0, "length": 966, "protein_name": "General transcriptional corepressor CYC8", "gene_name": "CYC8", "organism": "Yeast", "refseq_name": "transcription regulator CYC8", "refseq_ac": "NP_009670", "gene_names_uniprotkb": "CYC8; CRT8; SSN6; YBR0908", "gene_names_refseq": "CRT8; CYC8; SSN6", "protein_names_uniprotkb": "General transcriptional corepressor CYC8; Glucose repression mediator protein CYC8", "protein_names_refseq": "transcription regulator CYC8", "tax_id": 559292, "disease": "triple-receptor negative breast cancer (Disease Ontology:DOID:0060081); Kabuki syndrome (Disease Ontology:DOID:0060473); chronic myelomonocytic leukemia (Disease Ontology:DOID:0080188); adenoid cystic carcinoma (Disease Ontology:DOID:0080202); Stolerman neurodevelopmental syndrome (Disease Ontology:DOID:0081443); prostate cancer (Disease Ontology:DOID:10283); stomach cancer (Disease Ontology:DOID:10534); alcohol use disorder (Disease Ontology:DOID:1574); breast cancer (Disease Ontology:DOID:1612); rectum adenocarcinoma (Disease Ontology:DOID:1996); colon adenocarcinoma (Disease Ontology:DOID:234); breast carcinoma (Disease Ontology:DOID:3459); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung non-small cell carcinoma (Disease Ontology:DOID:3908); bladder urothelial carcinoma (Disease Ontology:DOID:4006); renal cell carcinoma (Disease Ontology:DOID:4450); lung small cell carcinoma (Disease Ontology:DOID:5409); myocardial infarction (Disease Ontology:DOID:5844); hepatocellular carcinoma (Disease Ontology:DOID:684); malignant pleural mesothelioma (Disease Ontology:DOID:7474); colorectal cancer (Disease Ontology:DOID:9256); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (sce:YBR112C); (R-SCE-2559580)", "pathway_count": 2, "publication_count": 41, "publication_id_list": "10722672;10759558;11069890;11230135;11401714;11784848;12086626;14525981;14562106;14665463;15665377;1626431;17287358;17330950;17563356;18407956;19219034;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22218487;23749301;2404612;24374639;24909858;2854095;30516470;32597660;3316983;33229814;33481703;33491328;7498787;7724528;7813418;8943325;9741624", "class_list": "", "function": "Acts as a component of the CYC8-TUP1 corepressor complex which is involved in the repression of many genes in a wide variety of physiological processes including heme-regulated and catabolite repressed genes. May also be involved in the derepression of at least some target genes. The complex is recruited to target genes by interaction with DNA-bound transcriptional repressors, like MATALPHA2, MIG1, RFX1 and SKO1. The complex recruits histone deacetylases to produce a repressive chromatin structure, interacts with hypoacetylated N-terminal tails of histones H3 and H4 that have been programmed for repression by the action of histone deacetylases and interferes directly with the transcriptional machinery by associating with the RNA polymerase II mediator complex., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 40, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 22, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VQB2", "ec_number_list": "", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0003714 transcription corepressor activity;GO:0042826 histone deacetylase binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0031490 chromatin DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0017053 transcription repressor complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0000278 mitotic cell cycle;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 4.5, "record_id": "P14922-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15019-1", "uniprot_id": "TAL1_YEAST", "mass": 37036.0, "length": 335, "protein_name": "Transaldolase", "gene_name": "TAL1", "organism": "Yeast", "refseq_name": "sedoheptulose-7-phosphate:D-glyceraldehyde-3- phosphate transaldolase TAL1", "refseq_ac": "NP_013458", "gene_names_uniprotkb": "TAL1; L9638.6", "gene_names_refseq": "TAL1", "protein_names_uniprotkb": "Transaldolase; 2.2.1.2", "protein_names_refseq": "sedoheptulose-7-phosphate:D-glyceraldehyde-3- phosphate transaldolase TAL1", "tax_id": 559292, "disease": "carbohydrate metabolic disorder (Disease Ontology:DOID:2978)", "pathway": " (sce:YLR354C); (R-SCE-163754); (R-SCE-71336)", "pathway_count": 3, "publication_count": 13, "publication_id_list": "14562106;18407956;19779198;20702584;2185015;23749301;24374639;3027658;33481703;33491328;8109173;9169871;9298649", "class_list": "", "function": "Transaldolase involved in the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedoheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate. Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 18, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYZ2", "ec_number_list": "2.2.1.2", "go_molecular_function": "GO:0004801 transaldolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0009052 pentose-phosphate shunt, non-oxidative branch;GO:0005975 carbohydrate metabolic process;GO:0006098 pentose-phosphate shunt", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P15019-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15180-1", "uniprot_id": "SYKC_YEAST", "mass": 67959.0, "length": 591, "protein_name": "Lysine--tRNA ligase, cytoplasmic", "gene_name": "KRS1", "organism": "Yeast", "refseq_name": "lysine--tRNA ligase KRS1", "refseq_ac": "NP_010322", "gene_names_uniprotkb": "KRS1; GCD5; YD9673.09", "gene_names_refseq": "GCD5; KRS1", "protein_names_uniprotkb": "Lysine--tRNA ligase, cytoplasmic; 6.1.1.6; LysRS; Lysyl-tRNA synthetase", "protein_names_refseq": "lysine--tRNA ligase KRS1", "tax_id": 559292, "disease": "hypomyelinating leukoencephalopathy (Disease Ontology:DOID:0050987); Charcot-Marie-Tooth disease recessive intermediate B (Disease Ontology:DOID:0110204); autosomal recessive nonsyndromic deafness 89 (Disease Ontology:DOID:0110534); sciatic neuropathy (Disease Ontology:DOID:11446); ophthalmoplegia (Disease Ontology:DOID:539)", "pathway": " (sce:YDR037W); (R-SCE-9856649)", "pathway_count": 2, "publication_count": 18, "publication_id_list": "1505029;17287358;17330950;17563356;18407956;19779198;2046655;21126336;22106047;23749301;24374639;2903861;32597660;33481703;33491328;7895733;9169867;9298649", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 18, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS25", "ec_number_list": "6.1.1.6", "go_molecular_function": "GO:1990825 sequence-specific mRNA binding;GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0000049 tRNA binding;GO:0004824 lysine-tRNA ligase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006430 lysyl-tRNA aminoacylation", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P15180-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15202-1", "uniprot_id": "CATA_YEAST", "mass": 58555.0, "length": 515, "protein_name": "Peroxisomal catalase A", "gene_name": "CTA1", "organism": "Yeast", "refseq_name": "catalase A", "refseq_ac": "NP_010542", "gene_names_uniprotkb": "CTA1; YD9320A.06C", "gene_names_refseq": "CTA1", "protein_names_uniprotkb": "Peroxisomal catalase A; 1.11.1.6", "protein_names_refseq": "catalase A", "tax_id": 559292, "disease": "pterygium (Disease Ontology:DOID:0002116); chronic venous insufficiency (Disease Ontology:DOID:0050853); colitis (Disease Ontology:DOID:0060180); alcohol-associated liver disease (Disease Ontology:DOID:0070658); colorectal carcinoma (Disease Ontology:DOID:0080199); Graves ophthalmopathy (Disease Ontology:DOID:0081120); sensorineural hearing loss (Disease Ontology:DOID:10003); osteonecrosis (Disease Ontology:DOID:10159); Raynaud disease (Disease Ontology:DOID:10300); pneumoconiosis (Disease Ontology:DOID:10316); retinitis pigmentosa (Disease Ontology:DOID:10584); otitis media (Disease Ontology:DOID:10754); hypertension (Disease Ontology:DOID:10763); gastric ulcer (Disease Ontology:DOID:10808); essential hypertension (Disease Ontology:DOID:10825); sciatic neuropathy (Disease Ontology:DOID:11446); bronchopulmonary dysplasia (Disease Ontology:DOID:11650); optic neuritis (Disease Ontology:DOID:1210); tympanosclerosis (Disease Ontology:DOID:1214); vitiligo (Disease Ontology:DOID:12306); Graves' disease (Disease Ontology:DOID:12361); newborn respiratory distress syndrome (Disease Ontology:DOID:12716); Huntington's disease (Disease Ontology:DOID:12858); neurodegenerative disease (Disease Ontology:DOID:1289); dilated cardiomyopathy (Disease Ontology:DOID:12930); proliferative diabetic retinopathy (Disease Ontology:DOID:13207); background diabetic retinopathy (Disease Ontology:DOID:13208); Behcet's disease (Disease Ontology:DOID:13241); angle-closure glaucoma (Disease Ontology:DOID:13550); cholestasis (Disease Ontology:DOID:13580); hypothyroidism (Disease Ontology:DOID:1459); alcohol use disorder (Disease Ontology:DOID:1574); depressive disorder (Disease Ontology:DOID:1596); keratosis (Disease Ontology:DOID:161); cystitis (Disease Ontology:DOID:1679); pancreatic cancer (Disease Ontology:DOID:1793); melanoma (Disease Ontology:DOID:1909); brain ischemia (Disease Ontology:DOID:2316); nephrosis (Disease Ontology:DOID:2527); acatalasia (Disease Ontology:DOID:2582); pseudoxanthoma elasticum (Disease Ontology:DOID:2738); asthma (Disease Ontology:DOID:2841); laryngeal squamous cell carcinoma (Disease Ontology:DOID:2876); familial Mediterranean fever (Disease Ontology:DOID:2987); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); breast adenocarcinoma (Disease Ontology:DOID:3458); toxic encephalopathy (Disease Ontology:DOID:3602); gastric adenocarcinoma (Disease Ontology:DOID:3717); pulmonary fibrosis (Disease Ontology:DOID:3770); papillary thyroid carcinoma (Disease Ontology:DOID:3969); ureteral obstruction (Disease Ontology:DOID:5199); retinal disease (Disease Ontology:DOID:5679); myocardial infarction (Disease Ontology:DOID:5844); nephrolithiasis (Disease Ontology:DOID:585); congestive heart failure (Disease Ontology:DOID:6000); fibromyalgia (Disease Ontology:DOID:631); acne (Disease Ontology:DOID:6543); amphetamine abuse (Disease Ontology:DOID:670); hepatocellular carcinoma (Disease Ontology:DOID:684); end stage renal disease (Disease Ontology:DOID:783); hyperthyroidism (Disease Ontology:DOID:7998); scabies (Disease Ontology:DOID:8295); cataract (Disease Ontology:DOID:83); lung disease (Disease Ontology:DOID:850); bacterial pneumonia (Disease Ontology:DOID:874); seborrheic dermatitis (Disease Ontology:DOID:8741); psoriasis (Disease Ontology:DOID:8893); diabetic retinopathy (Disease Ontology:DOID:8947); cutaneous leishmaniasis (Disease Ontology:DOID:9111); pemphigus (Disease Ontology:DOID:9182); lichen planus (Disease Ontology:DOID:9201); phenylketonuria (Disease Ontology:DOID:9281); type 2 diabetes mellitus (Disease Ontology:DOID:9352); steatotic liver disease (Disease Ontology:DOID:9452); stomatitis (Disease Ontology:DOID:9637); senile cataract (Disease Ontology:DOID:9669); neovascular inflammatory vitreoretinopathy (Disease Ontology:DOID:9719)", "pathway": " (sce:YDR256C); (R-SCE-3299685); (R-SCE-6798695); (R-SCE-9033241)", "pathway_count": 4, "publication_count": 9, "publication_id_list": "14562106;17322287;1986244;22814378;24374639;3046940;33491328;9169867;9931255", "class_list": "", "function": "Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 77, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSN6;E9P947", "ec_number_list": "2.7.1.40;5.4.2.11;2.7.1.1;4.2.1.24;1.11.1.6;3.6.4.13;2.4.1.1;3.4.23.25;3.6.4.10;5.3.1.9;5.1.3.-;5.2.1.8;3.5.4.6;1.6.2.4;2.7.1.11;2.7.1.2;1.1.1.42;3.4.25.1;3.6.4.6;3.6.5.-;2.7.11.24;1.3.1.124;2.3.1.7;3.6.4.12;5.4.2.2;1.11.1.24;2.7.4.6;2.4.1.186;1.1.1.205;2.7.1.35;4.1.2.63;3.1.2.2;3.4.19.12;2.4.2.7;5.4.2.7;2.3.2.26;2.7.11.23;2.3.2.27;2.4.2.1;5.3.3.8;3.4.24.-;2.7.1.59;3.5.4.5;3.4.11.-;3.3.2.10;3.6.1.-;3.6.1.56;3.6.1.77", "go_molecular_function": "GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0004096 catalase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0005777 peroxisome;GO:0005782 peroxisomal matrix", "go_biological_process": "GO:0042542 response to hydrogen peroxide;GO:0000302 response to reactive oxygen species;GO:0042744 hydrogen peroxide catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P15202-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15274-1", "uniprot_id": "AMPD_YEAST", "mass": 93302.0, "length": 810, "protein_name": "AMP deaminase", "gene_name": "AMD1", "organism": "Yeast", "refseq_name": "AMP deaminase", "refseq_ac": "NP_013677", "gene_names_uniprotkb": "AMD1; AMD", "gene_names_refseq": "AMD1; AMD3", "protein_names_uniprotkb": "AMP deaminase; 3.5.4.6; Myoadenylate deaminase", "protein_names_refseq": "AMP deaminase", "tax_id": 559292, "disease": "left ventricular failure (Disease Ontology:DOID:0051064); pontocerebellar hypoplasia (Disease Ontology:DOID:0060264); pontocerebellar hypoplasia type 9 (Disease Ontology:DOID:0060278); hereditary spastic paraplegia 63 (Disease Ontology:DOID:0110814); coronary artery disease (Disease Ontology:DOID:3393); lung adenocarcinoma (Disease Ontology:DOID:3910); congestive heart failure (Disease Ontology:DOID:6000)", "pathway": " (sce:YML035C); (R-SCE-6798695); (R-SCE-74217)", "pathway_count": 3, "publication_count": 23, "publication_id_list": "14562106;15665377;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21177495;22218487;22814378;23749301;24374639;24909858;2690949;32597660;33481703;33491328;34965436;9169872", "class_list": "", "function": "AMP deaminase plays a critical role in energy metabolism., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 21, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZE0", "ec_number_list": "2.7.1.40;5.4.2.11;2.7.1.1;4.2.1.24;3.6.4.13;2.4.1.1;3.4.23.25;3.6.4.10;5.3.1.9;5.1.3.-;5.2.1.8;1.11.1.6;3.5.4.6;2.7.1.11;2.7.1.2;1.1.1.42;3.4.25.1;3.6.4.6;3.6.5.-;2.7.11.24;3.6.4.12;5.4.2.2;1.11.1.24;2.7.4.6;2.4.1.186;1.1.1.205;2.7.1.35;3.4.19.12;2.4.2.7;5.4.2.7;2.3.2.26;2.7.11.23;2.4.2.1;2.7.1.59;3.5.4.5;3.4.11.-;3.3.2.10", "go_molecular_function": "GO:0046872 metal ion binding;GO:0003876 AMP deaminase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0046033 AMP metabolic process;GO:0006188 IMP biosynthetic process;GO:0032264 IMP salvage;GO:0006163 purine nucleotide metabolic process;GO:0006178 guanine salvage", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P15274-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15315-1", "uniprot_id": "CUP2_YEAST", "mass": 24425.0, "length": 225, "protein_name": "Transcriptional activator protein CUP2", "gene_name": "CUP2", "organism": "Yeast", "refseq_name": "Cup2p", "refseq_ac": "NP_011349", "gene_names_uniprotkb": "CUP2; ACE1; G1810", "gene_names_refseq": "ACE1; CUP2", "protein_names_uniprotkb": "Transcriptional activator protein CUP2; Copper-fist transcription factor", "protein_names_refseq": "Cup2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL166W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "14562106;17322287;24374639;2651899;2674688;3052856;32597660;33491328;8509391;8585324;9169869", "class_list": "", "function": "Trans-acting regulatory protein that activates transcription of the CUP1 gene (metallothionein) in response to copper ions. Binds to the CUP1 UAS sequence 5'-GCTTCTTTTCCGCTGA-3'. Binds DNA only in presence of copper or silver. Copper seems to alter the conformation of the protein., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTY6", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0005507 copper ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006878 intracellular copper ion homeostasis;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006879 intracellular iron ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P15315-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15367-1", "uniprot_id": "SEC11_YEAST", "mass": 18762.0, "length": 167, "protein_name": "Signal peptidase complex catalytic subunit SEC11", "gene_name": "SEC11", "organism": "Yeast", "refseq_name": "signal peptidase complex catalytic subunit SEC11", "refseq_ac": "NP_012288", "gene_names_uniprotkb": "SEC11", "gene_names_refseq": "SEC11", "protein_names_uniprotkb": "Signal peptidase complex catalytic subunit SEC11; 3.4.21.89; Secretory protein 11; Signal peptidase I", "protein_names_refseq": "signal peptidase complex catalytic subunit SEC11", "tax_id": 559292, "disease": "", "pathway": " (sce:YIR022W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10206957;11058593;14562095;14562106;17322287;1846444;24374639;2644273;3283143;7615509;9148931;9169870", "class_list": "", "function": "Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (PubMed:10206957, PubMed:11058593, PubMed:2644273, PubMed:7615509). Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity)., [UniProtKB, UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 9, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VVV3", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0008233 peptidase activity;GO:0009003 signal peptidase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0005787 signal peptidase complex", "go_biological_process": "GO:0045047 protein targeting to ER;GO:0006465 signal peptide processing", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P15367-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15424-1", "uniprot_id": "MS116_YEAST", "mass": 76269.0, "length": 664, "protein_name": "ATP-dependent RNA helicase MSS116, mitochondrial", "gene_name": "MSS116", "organism": "Yeast", "refseq_name": "ATP-dependent RNA helicase", "refseq_ac": "NP_010480", "gene_names_uniprotkb": "MSS116; YD9346.05C", "gene_names_refseq": "MSS116", "protein_names_uniprotkb": "ATP-dependent RNA helicase MSS116, mitochondrial; 3.6.4.13", "protein_names_refseq": "ATP-dependent RNA helicase", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR194C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "12402239;14562095;14562106;14576278;15618406;24374639;2535893;33491328;7567443;9169867", "class_list": "", "function": "ATP-dependent RNA helicase required for mitochondrial splicing of group I and II introns. Specifically involved in the ATP-dependent splicing of the bl1 intron of COB. Also required for efficient mitochondrial translation., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSH6", "ec_number_list": "3.6.4.13;5.6.2.3;3.6.4.10;3.6.-.-;5.6.2.4;3.6.4.-;5.6.1.4;3.6.4.12;3.6.4.6;5.6.2.5;3.6.1.-;2.3.2.27;3.1.-.-;3.4.24.-;3.6.5.-;2.7.4.3;2.7.11.1;7.2.2.-", "go_molecular_function": "GO:0003723 RNA binding;GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0002151 G-quadruplex RNA binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0005761 mitochondrial ribosome", "go_biological_process": "GO:0000963 mitochondrial RNA processing;GO:0070124 mitochondrial translational initiation;GO:0034337 RNA folding;GO:0006392 transcription elongation by mitochondrial RNA polymerase;GO:0006397 mRNA processing", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P15424-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15454-1", "uniprot_id": "KGUA_YEAST", "mass": 20637.0, "length": 187, "protein_name": "Guanylate kinase", "gene_name": "GUK1", "organism": "Yeast", "refseq_name": "guanylate kinase", "refseq_ac": "NP_010742", "gene_names_uniprotkb": "GUK1; D9461.39", "gene_names_refseq": "BRA3; GUK1; PUR5", "protein_names_uniprotkb": "Guanylate kinase; 2.7.4.8; GMP kinase", "protein_names_refseq": "guanylate kinase", "tax_id": 559292, "disease": "mitochondrial DNA depletion syndrome-21 (Disease Ontology:DOID:0051029); cancer (Disease Ontology:DOID:162)", "pathway": " (sce:YDR454C); (R-SCE-499943); (R-SCE-9748787)", "pathway_count": 3, "publication_count": 19, "publication_id_list": "1314905;1334480;14562106;17287358;17330950;17563356;18407956;1967656;19779198;19795423;19823750;20489023;20702584;21177495;24374639;2551688;33481703;33491328;9169867", "class_list": "", "function": "Catalyzes the reversible transfer of the terminal phosphoryl group of ATP to the acceptor molecule GMP. Essential for recycling GMP and indirectly, cGMP., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VT79", "ec_number_list": "2.7.4.8", "go_molecular_function": "GO:0004385 GMP kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0046711 GDP biosynthetic process;GO:0006163 purine nucleotide metabolic process", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P15454-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15496-1", "uniprot_id": "IDI1_YEAST", "mass": 33352.0, "length": 288, "protein_name": "Isopentenyl-diphosphate delta-isomerase", "gene_name": "IDI1", "organism": "Yeast", "refseq_name": "isopentenyl-diphosphate delta-isomerase IDI1", "refseq_ac": "NP_015208", "gene_names_uniprotkb": "IDI1; BOT2; LPH10C", "gene_names_refseq": "BOT2; IDI1; LPH10", "protein_names_uniprotkb": "Isopentenyl-diphosphate delta-isomerase; 5.3.3.2; IPP isomerase; Isopentenyl pyrophosphate isomerase", "protein_names_refseq": "isopentenyl-diphosphate delta-isomerase IDI1", "tax_id": 559292, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (sce:YPL117C); (R-SCE-9969896)", "pathway_count": 2, "publication_count": 14, "publication_id_list": "14562106;17330950;17563356;18407956;19779198;2223785;23749301;24374639;2681212;32679672;33481703;33491328;7908830;9169875", "class_list": "", "function": "Isopentenyl-diphosphate delta-isomerase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway (PubMed:2223785, PubMed:2681212, PubMed:7908830). IDI1 catalyzes the 1,3-allylic rearrangement of isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (PubMed:2223785, PubMed:2681212, PubMed:7908830). The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins. Activity by the mevalonate kinase ERG12 first converts mevalonate into 5-phosphomevalonate. 5-phosphomevalonate is then further converted to 5-diphosphomevalonate by the phosphomevalonate kinase ERG8. The diphosphomevalonate decarboxylase MVD1/ERG19 then produces isopentenyl diphosphate. The isopentenyl-diphosphate delta-isomerase IDI1 then catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). Finally the farnesyl diphosphate synthase ERG20 catalyzes the sequential condensation of isopentenyl pyrophosphate with dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate (PubMed:32679672)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3Q1", "ec_number_list": "5.3.3.2", "go_molecular_function": "GO:0004452 isopentenyl-diphosphate delta-isomerase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005773 vacuole", "go_biological_process": "GO:0009240 isopentenyl diphosphate biosynthetic process;GO:0050992 dimethylallyl diphosphate biosynthetic process;GO:0006696 ergosterol biosynthetic process;GO:0045337 farnesyl diphosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P15496-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15565-1", "uniprot_id": "TRM1_YEAST", "mass": 64052.0, "length": 570, "protein_name": "tRNA (guanine(26)-N(2))-dimethyltransferase, mitochondrial", "gene_name": "TRM1", "organism": "Yeast", "refseq_name": "tRNA (guanine26-N2)-dimethyltransferase", "refseq_ac": "NP_010405", "gene_names_uniprotkb": "TRM1; YD9727.15C", "gene_names_refseq": "TRM1", "protein_names_uniprotkb": "tRNA (guanine(26)-N(2))-dimethyltransferase, mitochondrial; 2.1.1.216; tRNA 2,2-dimethylguanosine-26 methyltransferase; tRNA(guanine-26,N(2)-N(2)) methyltransferase; tRNA(m(2,2)G26)dimethyltransferase", "protein_names_refseq": "tRNA (guanine26-N2)-dimethyltransferase", "tax_id": 559292, "disease": "autosomal recessive intellectual developmental disorder 68 (Disease Ontology:DOID:0081229)", "pathway": " (sce:YDR120C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10048958;14562106;15911569;19602197;19684113;23749301;24374639;32597660;3299379;33491328;7599275;9169867;9801306", "class_list": "", "function": "Dimethylates a single guanine residue at position 26 of most tRNAs using S-adenosyl-L-methionine as donor of the methyl groups. Required for the modification of both mitochondrial and cytoplasmic tRNAs., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSA6;Q9URQ7;Q9URQ8", "ec_number_list": "2.1.1.216", "go_molecular_function": "GO:0046872 metal ion binding;GO:0000049 tRNA binding;GO:0160104 tRNA (guanine(26)-N2)-dimethyltransferase activity;GO:0160103 tRNA (guanine(26)-N2/guanine(27)-N2)-dimethyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005739 mitochondrion;GO:0005637 nuclear inner membrane", "go_biological_process": "GO:0008033 tRNA processing;GO:0030488 tRNA methylation", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P15565-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15624-1", "uniprot_id": "SYFB_YEAST", "mass": 67365.0, "length": 595, "protein_name": "Phenylalanine--tRNA ligase beta subunit", "gene_name": "FRS1", "organism": "Yeast", "refseq_name": "phenylalanine--tRNA ligase subunit beta", "refseq_ac": "NP_013161", "gene_names_uniprotkb": "FRS1; L2165", "gene_names_refseq": "FRS1", "protein_names_uniprotkb": "Phenylalanine--tRNA ligase beta subunit; 6.1.1.20; PheRS; Phenylalanyl-tRNA synthetase beta subunit", "protein_names_refseq": "phenylalanine--tRNA ligase subunit beta", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR060W)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "14562106;17322287;17563356;18407956;23749301;24374639;3049607;32597660;33481703;33491328;33502312;338359;9169871", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 16, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VY62;E9P8X0", "ec_number_list": "6.1.1.20", "go_molecular_function": "GO:1990825 sequence-specific mRNA binding;GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0004826 phenylalanine-tRNA ligase activity", "go_cellular_component": "GO:0009328 phenylalanine-tRNA ligase complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0006432 phenylalanyl-tRNA aminoacylation", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P15624-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15700-1", "uniprot_id": "KCY_YEAST", "mass": 22933.0, "length": 204, "protein_name": "Uridylate kinase", "gene_name": "URA6", "organism": "Yeast", "refseq_name": "bifunctional uridylate/adenylate kinase", "refseq_ac": "NP_012901", "gene_names_uniprotkb": "URA6; SOC8", "gene_names_refseq": "SOC8; URA6", "protein_names_uniprotkb": "Uridylate kinase; 2.7.4.14; ATP:UMP phosphotransferase; CK; Deoxycytidylate kinase; Suppressor of cdc8 protein; UK; UMP kinase; UMPK; Uridine monophosphate kinase; dCMP kinase", "protein_names_refseq": "bifunctional uridylate/adenylate kinase", "tax_id": 559292, "disease": "cancer (Disease Ontology:DOID:162); lung non-small cell carcinoma (Disease Ontology:DOID:3908)", "pathway": " (sce:YKL024C); (R-SCE-499943)", "pathway_count": 2, "publication_count": 15, "publication_id_list": "1333436;14562106;16240436;1655742;17322287;2172245;24374639;2549068;2556145;33481703;33491328;7877173;8107116;8196765;8391780", "class_list": "", "function": "Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP, AMP, GMP, dGMP and dTMP. ATP and dATP are the best phosphate donors, but can also use GTP, dGTP, dCTP, and dTTP to some degree., [UniProtKB, PubMed, HAMAP, PubMed, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXR0", "ec_number_list": "2.7.4.14", "go_molecular_function": "GO:0004017 AMP kinase activity;GO:0005524 ATP binding;GO:0033862 UMP kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006139 nucleobase-containing compound metabolic process;GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process;GO:0006225 UDP biosynthetic process;GO:0046705 CDP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P15700-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15703-1", "uniprot_id": "BGL2_YEAST", "mass": 34119.0, "length": 313, "protein_name": "Glucan 1,3-beta-glucosidase", "gene_name": "BGL2", "organism": "Yeast", "refseq_name": "glucan 1,3-beta-glucosidase", "refseq_ac": "NP_011798", "gene_names_uniprotkb": "BGL2; SCW9", "gene_names_refseq": "BGL2; SCW9", "protein_names_uniprotkb": "Glucan 1,3-beta-glucosidase; 3.2.1.58; Exo-1,3-beta-glucanase; GP29; Soluble cell wall protein 9", "protein_names_refseq": "glucan 1,3-beta-glucosidase", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR282C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "14562106;17322287;23749301;24374639;2509432;33167499;33481703;33491328;8458852;8935650;9090054;9169869;9748433", "class_list": "", "function": "Glucanases possibly play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation and also function biosynthetically as a transglycosylase., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 1, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 1, "mined_n_glycosites": 1, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VV59", "ec_number_list": "", "go_molecular_function": "GO:0008061 chitin binding;GO:0042973 glucan endo-1,3-beta-D-glucosidase activity;GO:0004338 glucan exo-1,3-beta-glucosidase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0009986 cell surface;GO:0000324 fungal-type vacuole;GO:0009277 fungal-type cell wall", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0031505 fungal-type cell wall organization;GO:0071555 cell wall organization", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P15703-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15731-1", "uniprot_id": "UBC4_YEAST", "mass": 16456.0, "length": 148, "protein_name": "Ubiquitin-conjugating enzyme E2 4", "gene_name": "UBC4", "organism": "Yeast", "refseq_name": "E2 ubiquitin-conjugating protein UBC4", "refseq_ac": "NP_009638", "gene_names_uniprotkb": "UBC4; YBR0745", "gene_names_refseq": "UBC4", "protein_names_uniprotkb": "Ubiquitin-conjugating enzyme E2 4; 2.3.2.23; E2 ubiquitin-conjugating enzyme 4; Ubiquitin carrier protein 4; Ubiquitin-protein ligase 4", "protein_names_refseq": "E2 ubiquitin-conjugating protein UBC4", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR082C); (R-SCE-9033241); (R-SCE-983168)", "pathway_count": 3, "publication_count": 12, "publication_id_list": "11788821;14562106;17550898;18407956;2154373;22106047;24374639;28757607;33491328;7813418;7985423;8268156", "class_list": "", "function": "E2 ubiquitin-conjugating enzyme that catalyzes the covalent attachment of ubiquitin to other proteins (PubMed:17550898). Mediates the selective degradation of short-lived and abnormal proteins (PubMed:17550898). Mediates ubiquitination of PEX5 (PubMed:17550898)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQ81", "ec_number_list": "2.3.2.23;2.3.2.27;6.2.1.45;2.3.2.-;2.3.2.26;2.3.2.31;1.14.11.27;2.3.2.34;6.3.2.-", "go_molecular_function": "GO:0005524 ATP binding;GO:0030674 protein-macromolecule adaptor activity;GO:0004842 ubiquitin-protein transferase activity;GO:0043130 ubiquitin binding;GO:0070628 proteasome binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0072344 rescue of stalled ribosome;GO:0034605 cellular response to heat;GO:0000209 protein polyubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0072671 mitochondria-associated ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P15731-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15732-1", "uniprot_id": "UBC5_YEAST", "mass": 16281.0, "length": 148, "protein_name": "Ubiquitin-conjugating enzyme E2-16 kDa", "gene_name": "UBC5", "organism": "Yeast", "refseq_name": "E2 ubiquitin-conjugating protein UBC5", "refseq_ac": "NP_010344", "gene_names_uniprotkb": "UBC5; D4234; YD9609.13C", "gene_names_refseq": "UBC5", "protein_names_uniprotkb": "Ubiquitin-conjugating enzyme E2-16 kDa; 2.3.2.23; E2 ubiquitin-conjugating enzyme 5; Ubiquitin carrier protein; Ubiquitin-protein ligase", "protein_names_refseq": "E2 ubiquitin-conjugating protein UBC5", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR059C); (R-SCE-9033241); (R-SCE-983168)", "pathway_count": 3, "publication_count": 7, "publication_id_list": "14562106;19920177;2154373;24374639;33229814;8789263;9169867", "class_list": "", "function": "Catalyzes the covalent attachment of ubiquitin to other proteins (PubMed:19920177, PubMed:2154373). Mediates the selective degradation of short-lived and abnormal proteins (PubMed:2154373). The RSP5-UBA1-UBC5 ubiquitin ligase complex ubiquitinates RPO21 forming 'Lys-63'-linked polyubiquitin chains (PubMed:19920177)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VS45", "ec_number_list": "2.3.2.23;2.3.2.27;6.2.1.45;2.3.2.-;2.3.2.26;2.3.2.31;1.14.11.27;2.3.2.34;6.3.2.-", "go_molecular_function": "GO:0005524 ATP binding;GO:0004842 ubiquitin-protein transferase activity;GO:0070628 proteasome binding;GO:0061631 ubiquitin conjugating enzyme activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000209 protein polyubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P15732-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15790-1", "uniprot_id": "CSK21_YEAST", "mass": 44668.0, "length": 372, "protein_name": "Casein kinase II subunit alpha", "gene_name": "CKA1", "organism": "Yeast", "refseq_name": "casein kinase 2 catalytic subunit CKA1", "refseq_ac": "NP_012229", "gene_names_uniprotkb": "CKA1", "gene_names_refseq": "CKA1", "protein_names_uniprotkb": "Casein kinase II subunit alpha; 2.7.11.1; CK II subunit alpha", "protein_names_refseq": "casein kinase 2 catalytic subunit CKA1", "tax_id": 559292, "disease": "male infertility (Disease Ontology:DOID:12336); breast cancer (Disease Ontology:DOID:1612); myocardial infarction (Disease Ontology:DOID:5844)", "pathway": " (sce:YIL035C); (R-SCE-2514853); (R-SCE-6804756); (R-SCE-8934903); (R-SCE-8948751)", "pathway_count": 5, "publication_count": 9, "publication_id_list": "12242279;1315784;14562106;17322287;22156209;24374639;3062376;3468112;9169870", "class_list": "", "function": "Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine (By similarity). Phosphorylates YTA7 during S-phase to promote transcription of histones (PubMed:22156209)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVP7", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.1.1.-;2.7.11.17;2.7.11.23;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.6.4.13;3.6.-.-;3.1.3.67;2.1.1.260;3.6.5.-;3.6.1.-", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005956 protein kinase CK2 complex;GO:0032040 small-subunit processome", "go_biological_process": "GO:0006974 DNA damage response;GO:0051726 regulation of cell cycle;GO:0006359 regulation of transcription by RNA polymerase III;GO:0000028 ribosomal small subunit assembly;GO:0006356 regulation of transcription by RNA polymerase I", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P15790-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15801-1", "uniprot_id": "DPOG_YEAST", "mass": 143502.0, "length": 1254, "protein_name": "DNA polymerase gamma", "gene_name": "MIP1", "organism": "Yeast", "refseq_name": "DNA-directed DNA polymerase gamma MIP1", "refseq_ac": "NP_014975", "gene_names_uniprotkb": "MIP1", "gene_names_refseq": "MIP1", "protein_names_uniprotkb": "DNA polymerase gamma; 2.7.7.7; Mitochondrial DNA polymerase catalytic subunit", "protein_names_refseq": "DNA-directed DNA polymerase gamma MIP1", "tax_id": 559292, "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); cerebellar ataxia (Disease Ontology:DOID:0050753); myelodysplastic syndrome (Disease Ontology:DOID:0050908); Alpers-Huttenlocher syndrome (Disease Ontology:DOID:0080122); mitochondrial DNA depletion syndrome 4b (Disease Ontology:DOID:0080123); sensory ataxic neuropathy, dysarthria, and ophthalmoparesis (Disease Ontology:DOID:0111276); autosomal dominant progressive external ophthalmoplegia 1 (Disease Ontology:DOID:0111521); autosomal recessive progressive external ophthalmoplegia 1 (Disease Ontology:DOID:0111522); premature menopause (Disease Ontology:DOID:10787); chronic progressive external ophthalmoplegia (Disease Ontology:DOID:12558); Parkinson's disease (Disease Ontology:DOID:14330); status epilepticus (Disease Ontology:DOID:1824); epilepsy (Disease Ontology:DOID:1826); multiple sclerosis (Disease Ontology:DOID:2377); bipolar disorder (Disease Ontology:DOID:3312); mood disorder (Disease Ontology:DOID:3324); progeria (Disease Ontology:DOID:3911); primary ovarian insufficiency (Disease Ontology:DOID:5426); peripheral nervous system disease (Disease Ontology:DOID:574); hepatocellular carcinoma (Disease Ontology:DOID:684); mitochondrial metabolism disease (Disease Ontology:DOID:700); mitochondrial encephalomyopathy (Disease Ontology:DOID:890)", "pathway": " (sce:YOR330C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562106;21177495;24374639;2684980;33229814;8896263;9169874", "class_list": "", "function": "Involved in the replication of mitochondrial DNA., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 22, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6W327;Q08785", "ec_number_list": "2.7.7.7;3.1.26.4;2.7.7.49;3.4.23.-;3.1.11.-", "go_molecular_function": "GO:0003887 DNA-directed DNA polymerase activity;GO:0003677 DNA binding;GO:0008408 3'-5' exonuclease activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005760 gamma DNA polymerase complex", "go_biological_process": "GO:0006995 cellular response to nitrogen starvation;GO:0006264 mitochondrial DNA replication;GO:0032043 mitochondrial DNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P15801-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15807-1", "uniprot_id": "MET8_YEAST", "mass": 31918.0, "length": 274, "protein_name": "Siroheme biosynthesis protein MET8", "gene_name": "MET8", "organism": "Yeast", "refseq_name": "bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase MET8", "refseq_ac": "NP_009772", "gene_names_uniprotkb": "MET8; YBR1461", "gene_names_refseq": "MET8", "protein_names_uniprotkb": "Siroheme biosynthesis protein MET8", "protein_names_refseq": "bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase MET8", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR213W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10051442;11980703;21126336;2408020;24374639;7813418", "class_list": "", "function": "Catalyzes the conversion of precorrin-2 into siroheme. This reaction consist of the NAD-dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQK9", "ec_number_list": "1.3.1.76;4.99.1.4", "go_molecular_function": "GO:0004325 ferrochelatase activity;GO:0043115 precorrin-2 dehydrogenase activity;GO:0051266 sirohydrochlorin ferrochelatase activity", "go_cellular_component": "", "go_biological_process": "GO:0000103 sulfate assimilation;GO:0019354 siroheme biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P15807-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15891-1", "uniprot_id": "ABP1_YEAST", "mass": 65576.0, "length": 592, "protein_name": "Actin-binding protein", "gene_name": "ABP1", "organism": "Yeast", "refseq_name": "Abp1p", "refseq_ac": "NP_010012", "gene_names_uniprotkb": "ABP1; YCR88W", "gene_names_refseq": "ABP1", "protein_names_uniprotkb": "Actin-binding protein", "protein_names_refseq": "Abp1p", "tax_id": 559292, "disease": "sciatic neuropathy (Disease Ontology:DOID:11446); Parkinson's disease (Disease Ontology:DOID:14330); cognitive disorder (Disease Ontology:DOID:1561); transient cerebral ischemia (Disease Ontology:DOID:224); temporal lobe epilepsy (Disease Ontology:DOID:3328)", "pathway": " (sce:YCR088W)", "pathway_count": 1, "publication_count": 35, "publication_id_list": "10388809;11331312;11668184;11875433;11950888;14562095;14562106;14737190;15665377;1574125;15872087;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22106047;22218487;22814378;23749301;2405279;24374639;24909858;27821475;30516470;32597660;33481703;33491328;8552082", "class_list": "", "function": "Regulates ARP2/3 complex-mediated actin assembly. Recruits ARP2/3 complex to sides of preexisting actin filaments, which may promote nucleation or stabilization of filament branches. Binds to actin filaments, but not actin monomers. Actin binding is required for ARP2/3 complex activation. May also have a role in linking the actin cytoskeleton to endocytosis. recruits components of the endocytotic machinery to cortical actin patches, known sites of endocytosis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 47, "reported_mutagensis": 11, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VR88", "ec_number_list": "", "go_molecular_function": "GO:0051015 actin filament binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005938 cell cortex;GO:0030864 cortical actin cytoskeleton;GO:0030479 actin cortical patch;GO:0030427 site of polarized growth", "go_biological_process": "GO:0051016 barbed-end actin filament capping;GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation;GO:0030833 regulation of actin filament polymerization;GO:0000147 actin cortical patch assembly;GO:0044379 protein localization to actin cortical patch", "synthesized_glycan_count": 0, "hit_score": 3.6, "record_id": "P15891-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15938-1", "uniprot_id": "PRP16_YEAST", "mass": 121653.0, "length": 1071, "protein_name": "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "gene_name": "PRP16", "organism": "Yeast", "refseq_name": "DEAH-box RNA helicase PRP16", "refseq_ac": "NP_013012", "gene_names_uniprotkb": "PRP16; YKR406", "gene_names_refseq": "PRP16; PRP23; RNA16", "protein_names_uniprotkb": "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16; 3.6.4.13", "protein_names_refseq": "DEAH-box RNA helicase PRP16", "tax_id": 559292, "disease": "retinitis pigmentosa 84 (Disease Ontology:DOID:0112141); retinitis pigmentosa (Disease Ontology:DOID:10584)", "pathway": " (sce:YKR086W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562106;1825134;21177495;2138057;23749301;24374639;33481703;33491328;8196765;8203164", "class_list": "", "function": "Influences the fidelity of branchpoint recognition in yeast splicing. This is RNA-dependent ATPase which is essential for viability. It may mediate one of the many ATP-requiring steps of spliceosome assembly and that accuracy of branchpoint recognition may be coupled to ATP binding and/or hydrolysis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXE6", "ec_number_list": "3.6.4.13;5.6.2.3;3.6.4.10;3.6.-.-;5.6.2.4;3.6.4.-;5.6.1.4;3.6.4.12;3.6.4.6;5.6.2.5;3.6.1.-;2.3.2.27;3.1.-.-;3.4.24.-;3.6.5.-;2.7.4.3;2.7.11.1;7.2.2.-", "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0034458 3'-5' RNA helicase activity;GO:0008186 ATP-dependent activity, acting on RNA", "go_cellular_component": "GO:0005681 spliceosomal complex;GO:0071007 U2-type catalytic step 2 spliceosome", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0000350 generation of catalytic spliceosome for second transesterification step;GO:0016073 snRNA metabolic process;GO:0040031 snRNA modification;GO:0000378 RNA exon ligation", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P15938-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15992-1", "uniprot_id": "HSP26_YEAST", "mass": 23880.0, "length": 214, "protein_name": "Heat shock protein 26", "gene_name": "HSP26", "organism": "Yeast", "refseq_name": "chaperone protein HSP26", "refseq_ac": "NP_009628", "gene_names_uniprotkb": "HSP26; YBR0714", "gene_names_refseq": "HSP26", "protein_names_uniprotkb": "Heat shock protein 26; 26 kDa heat shock protein", "protein_names_refseq": "chaperone protein HSP26", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR072W)", "pathway_count": 1, "publication_count": 21, "publication_id_list": "11875433;14562106;17322287;17563356;18407956;19684113;19779198;20190278;21126336;21177495;22218487;22814378;23749301;24374639;2673926;2689876;32597660;33491328;34795272;7813418;7985423", "class_list": "", "function": "Not known. One of the major polypeptides produced on heat shock., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQ71;Q6B1V5", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0042802 identical protein binding;GO:0051082 unfolded protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0034605 cellular response to heat;GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P15992-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P16140-1", "uniprot_id": "VATB_YEAST", "mass": 57749.0, "length": 517, "protein_name": "V-type proton ATPase subunit B", "gene_name": "VMA2", "organism": "Yeast", "refseq_name": "H(+)-transporting V1 sector ATPase subunit B", "refseq_ac": "NP_009685", "gene_names_uniprotkb": "VMA2; VAT2; YBR1002", "gene_names_refseq": "VAT2; VMA2", "protein_names_uniprotkb": "V-type proton ATPase subunit B; V-ATPase 57 kDa subunit; V-ATPase subunit B; Vacuolar proton pump subunit B", "protein_names_refseq": "H(+)-transporting V1 sector ATPase subunit B", "tax_id": 559292, "disease": "enlarged vestibular aqueduct (Disease Ontology:DOID:0050332); autosomal recessive nonsyndromic deafness (Disease Ontology:DOID:0050565); follicular lymphoma (Disease Ontology:DOID:0050873); autosomal dominant congenital deafness with onychodystrophy (Disease Ontology:DOID:0080720); renal tubular acidosis (Disease Ontology:DOID:14219); epilepsy (Disease Ontology:DOID:1826)", "pathway": " (sce:YBR127C); (R-SCE-1222556); (R-SCE-77387); (R-SCE-917977); (R-SCE-9639288)", "pathway_count": 5, "publication_count": 30, "publication_id_list": "11283612;1371275;14562106;15665377;17287358;17322287;17330950;17563356;18055462;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;2141385;22106047;23749301;24374639;2521486;25971514;27295975;30516470;32597660;33481703;33491328;7813418;8091856", "class_list": "", "function": "Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:2141385). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (PubMed:2141385)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 27, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQC4;P32123", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0046961 proton-transporting ATPase activity, rotational mechanism", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0045121 membrane raft;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0055085 transmembrane transport;GO:0006874 intracellular calcium ion homeostasis;GO:0046034 ATP metabolic process;GO:0048388 endosomal lumen acidification;GO:0007035 vacuolar acidification", "synthesized_glycan_count": 0, "hit_score": 3.1, "record_id": "P16140-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P16387-1", "uniprot_id": "ODPA_YEAST", "mass": 46343.0, "length": 420, "protein_name": "Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial", "gene_name": "PDA1", "organism": "Yeast", "refseq_name": "pyruvate dehydrogenase (acetyl-transferring) subunit E1 alpha", "refseq_ac": "NP_011105", "gene_names_uniprotkb": "PDA1", "gene_names_refseq": "PDA1", "protein_names_uniprotkb": "Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial; 1.2.4.1; PDHE1-A; Pyruvate dehydrogenase complex component E1 alpha", "protein_names_refseq": "pyruvate dehydrogenase (acetyl-transferring) subunit E1 alpha", "tax_id": 559292, "disease": "disease of metabolism (Disease Ontology:DOID:0014667); spermatogenic failure 70 (Disease Ontology:DOID:0070569); pyruvate decarboxylase deficiency (Disease Ontology:DOID:3649); retinal degeneration (Disease Ontology:DOID:8466)", "pathway": " (sce:YER178W); (R-SCE-9861559)", "pathway_count": 2, "publication_count": 28, "publication_id_list": "11875433;14562106;15665377;1581960;17287358;17330950;17563356;17761666;18180296;18407956;19684113;19779198;20702584;21126336;21177495;22218487;22814378;23749301;24374639;2684159;2722821;27821475;32597660;33481703;33491328;8017100;8455558;9169868", "class_list": "", "function": "The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DM87", "ec_number_list": "1.8.1.4;2.3.1.12;1.2.4.1", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0042645 mitochondrial nucleoid;GO:0045254 pyruvate dehydrogenase complex", "go_biological_process": "GO:0006086 pyruvate decarboxylation to acetyl-CoA;GO:0007124 pseudohyphal growth", "synthesized_glycan_count": 0, "hit_score": 2.9, "record_id": "P16387-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P16451-1", "uniprot_id": "ODPX_YEAST", "mass": 45362.0, "length": 410, "protein_name": "Pyruvate dehydrogenase complex protein X component, mitochondrial", "gene_name": "PDX1", "organism": "Yeast", "refseq_name": "Pdx1p", "refseq_ac": "NP_011709", "gene_names_uniprotkb": "PDX1; G7579", "gene_names_refseq": "PDX1", "protein_names_uniprotkb": "Pyruvate dehydrogenase complex protein X component, mitochondrial; Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex; E3-binding protein; Pyruvate dehydrogenase complex component E3BP", "protein_names_refseq": "Pdx1p", "tax_id": 559292, "disease": "sarcoma (Disease Ontology:DOID:1115); pyruvate decarboxylase deficiency (Disease Ontology:DOID:3649)", "pathway": " (sce:YGR193C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562106;17322287;2007123;24374639;2682658;33481703;33491328;7645350;9169869", "class_list": "", "function": "Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUX5;E9P906", "ec_number_list": "", "go_molecular_function": "GO:0005198 structural molecule activity;GO:0016746 acyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0045254 pyruvate dehydrogenase complex", "go_biological_process": "GO:0006086 pyruvate decarboxylation to acetyl-CoA", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P16451-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P16467-1", "uniprot_id": "PDC5_YEAST", "mass": 61912.0, "length": 563, "protein_name": "Pyruvate decarboxylase isozyme 2", "gene_name": "PDC5", "organism": "Yeast", "refseq_name": "indolepyruvate decarboxylase 5", "refseq_ac": "NP_013235", "gene_names_uniprotkb": "PDC5; L3133; L9606.7", "gene_names_refseq": "PDC5", "protein_names_uniprotkb": "Pyruvate decarboxylase isozyme 2; 2ODC; 4.1.1.-; 4.1.1.43; 4.1.1.72; 4.1.1.74; Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase", "protein_names_refseq": "indolepyruvate decarboxylase 5", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR134W)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "10231381;10234824;10338141;10753893;11141278;12499363;12902239;14562095;14562106;21177495;2185016;22904058;23642236;23749301;24374639;33491328;6383467;9169871;9341119;9655908;9655924;9748245", "class_list": "", "function": "Second most abundant of three pyruvate decarboxylases (PDC1, PDC5, PDC6) implicated in the nonoxidative conversion of pyruvate to acetaldehyde and carbon dioxide during alcoholic fermentation. Most of the produced acetaldehyde is subsequently reduced to ethanol, but some is required for cytosolic acetyl-CoA production for biosynthetic pathways. The enzyme is also one of five 2-oxo acid decarboxylases (PDC1, PDC5, PDC6, ARO10, and THI3) able to decarboxylate more complex 2-oxo acids (alpha-keto-acids) than pyruvate, which seem mainly involved in amino acid catabolism. Here the enzyme catalyzes the decarboxylation of amino acids, which, in a first step, have been transaminated to the corresponding 2-oxo acids. In a third step, the resulting aldehydes are reduced to alcohols, collectively referred to as fusel oils or alcohols. Its preferred substrates are the transaminated amino acids derived from threonine (2-oxobutanoate), norvaline (2-oxopentanoate), valine (3-methyl-2-oxobutanoate, also alpha-keto-isovalerate), isoleucine ((3S)-3-methyl-2-oxopentanoate, also alpha-keto-beta-methylvalerate), phenylalanine (phenylpyruvate), and tryptophan (3-(indol-3-yl)pyruvate), whereas transaminated leucine is no substrate. In a side-reaction the carbanionic intermediate (or active aldehyde) generated by decarboxylation or by activation of an aldehyde can react with an aldehyde via condensation (or carboligation) yielding a 2-hydroxy ketone, collectively called acyloins., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VYC9", "ec_number_list": "4.1.1.-;4.1.1.43;4.1.1.72;4.1.1.74;4.1.1.80", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0030976 thiamine pyrophosphate binding;GO:0004737 pyruvate decarboxylase activity;GO:0047433 branched-chain-2-oxoacid decarboxylase activity;GO:0047434 indolepyruvate decarboxylase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006569 L-tryptophan catabolic process;GO:0009083 branched-chain amino acid catabolic process;GO:0006559 L-phenylalanine catabolic process;GO:0000949 aromatic amino acid family catabolic process to alcohol via Ehrlich pathway;GO:0019655 glycolytic fermentation to ethanol", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "P16467-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P16474-1", "uniprot_id": "BIP_YEAST", "mass": 74468.0, "length": 682, "protein_name": "Endoplasmic reticulum chaperone BiP", "gene_name": "KAR2", "organism": "Yeast", "refseq_name": "Hsp70 family ATPase KAR2", "refseq_ac": "NP_012500", "gene_names_uniprotkb": "KAR2; GRP78; J1248; SSD1", "gene_names_refseq": "GRP78; KAR2", "protein_names_uniprotkb": "Endoplasmic reticulum chaperone BiP; 3.6.4.10; 78 kDa glucose-regulated protein homolog; BiP; GRP-78; Immunoglobulin heavy chain-binding protein homolog", "protein_names_refseq": "Hsp70 family ATPase KAR2", "tax_id": 559292, "disease": "inflammatory bowel disease (Disease Ontology:DOID:0050589); metabolic dysfunction-associated steatohepatitis (Disease Ontology:DOID:0080547); dopamine beta-hydroxylase deficiency (Disease Ontology:DOID:0090145); post-traumatic stress disorder (Disease Ontology:DOID:2055); transient cerebral ischemia (Disease Ontology:DOID:224); high grade glioma (Disease Ontology:DOID:3070); ureteral obstruction (Disease Ontology:DOID:5199); rheumatoid arthritis (Disease Ontology:DOID:7148); steatotic liver disease (Disease Ontology:DOID:9452)", "pathway": " (sce:YJL034W); (R-SCE-3371453)", "pathway_count": 2, "publication_count": 18, "publication_id_list": "14562106;14690591;16002399;16873065;17563356;18407956;19795423;19823750;2105497;21126336;23749301;24374639;2661018;2661019;32597660;33481703;33491328;8641269", "class_list": "", "function": "Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWE9", "ec_number_list": "3.6.4.13;5.6.2.3;3.6.4.10;3.6.-.-;5.6.2.4;3.6.4.-;5.6.1.4;3.6.4.12;3.6.4.6;5.6.2.5;3.6.1.-;2.3.2.27;3.1.-.-;3.4.24.-;3.6.5.-;2.7.4.3;2.7.11.1;7.2.2.-", "go_molecular_function": "GO:0005524 ATP binding;GO:0051082 unfolded protein binding;GO:0016887 ATP hydrolysis activity;GO:0031072 heat shock protein binding;GO:0015450 protein-transporting ATPase activity", "go_cellular_component": "GO:0034663 endoplasmic reticulum chaperone complex;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0005788 endoplasmic reticulum lumen", "go_biological_process": "GO:0030968 endoplasmic reticulum unfolded protein response;GO:0036503 ERAD pathway;GO:0070972 protein localization to endoplasmic reticulum;GO:0042026 protein refolding;GO:0031204 post-translational protein targeting to membrane, translocation", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P16474-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P16521-1", "uniprot_id": "EF3A_YEAST", "mass": 115945.0, "length": 1044, "protein_name": "Elongation factor 3A", "gene_name": "YEF3", "organism": "Yeast", "refseq_name": "translation elongation factor EF-3", "refseq_ac": "NP_013350", "gene_names_uniprotkb": "YEF3; EFC1; L9672.5; TEF3; YEF3A", "gene_names_refseq": "TEF3; YEF3", "protein_names_uniprotkb": "Elongation factor 3A; 3.6.4.-; EF-3A; EF-3; Eukaryotic elongation factor 3; Translation elongation factor 3A; Yeast elongation factor 3; eEF3", "protein_names_refseq": "translation elongation factor EF-3", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR249W)", "pathway_count": 1, "publication_count": 44, "publication_id_list": "10361693;10523624;11875433;12493761;14562095;14562106;16929303;17287358;17330950;17563356;18407956;19684113;1976386;19779198;19795423;19823750;20702584;21126336;2203789;22106047;22522802;22814378;22888004;23749301;2404974;24374639;29300771;30516470;32597660;33260587;33481703;33491328;36948349;6456269;7657623;7895733;7957240;8599608;9169871;9298649;9544245;9553076;9705146;9990316", "class_list": "", "function": "Ribosome-dependent ATPase that functions in cytoplasmic translation elongation (PubMed:29300771, PubMed:6456269, PubMed:7657623, PubMed:9705146, PubMed:36948349, PubMed:8599608). Required for the ATP-dependent release of deacylated tRNA from the ribosomal E-site during protein biosynthesis (PubMed:7657623, PubMed:9705146). Stimulates the eEF1A-dependent binding of aminoacyl-tRNA to the ribosomal A-site, which has reduced affinity for tRNA as long as the E-site is occupied (PubMed:7657623). Assists translation termination by stimulating the release of nascent protein from the ribosome by release factors (PubMed:36948349). In nutrient-replete conditions, occupies the space on the ribosome bound by GCN1 during amino acid starvation conditions, and therefore indirectly negatively regulates GCN2 kinase activity in replete conditions (PubMed:22888004)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 48, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYP7;O93815;Q06558", "ec_number_list": "3.6.4.13;5.6.2.3;3.6.4.10;3.6.-.-;5.6.2.4;3.6.4.-;5.6.1.4;3.6.4.12;3.6.4.6;5.6.2.5;3.6.1.-;2.3.2.27;3.1.-.-;3.4.24.-;3.6.5.-;2.7.4.3;2.7.11.1;7.2.2.-", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003746 translation elongation factor activity;GO:0019843 rRNA binding;GO:0043022 ribosome binding", "go_cellular_component": "GO:0005840 ribosome;GO:0022626 cytosolic ribosome;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0002184 cytoplasmic translational termination;GO:0006415 translational termination;GO:0006414 translational elongation;GO:0002182 cytoplasmic translational elongation", "synthesized_glycan_count": 0, "hit_score": 4.5, "record_id": "P16521-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P16522-1", "uniprot_id": "CDC23_YEAST", "mass": 73114.0, "length": 626, "protein_name": "Anaphase-promoting complex subunit CDC23", "gene_name": "CDC23", "organism": "Yeast", "refseq_name": "anaphase promoting complex subunit CDC23", "refseq_ac": "NP_012036", "gene_names_uniprotkb": "CDC23", "gene_names_refseq": "CDC23", "protein_names_uniprotkb": "Anaphase-promoting complex subunit CDC23; Cell division control protein 23", "protein_names_refseq": "anaphase promoting complex subunit CDC23", "tax_id": 559292, "disease": "infertility (Disease Ontology:DOID:5223)", "pathway": " (sce:YHR166C); (R-SCE-983168)", "pathway_count": 2, "publication_count": 16, "publication_id_list": "10871279;12413490;12609981;14562095;14562106;15280225;18407956;2205535;23749301;2404612;24374639;33481703;33491328;7925276;8091229;8423787", "class_list": "", "function": "Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome. In early mitosis, the APC/C is activated by CDC20 and targets securin PDS1, the B-type cyclin CLB5, and other anaphase inhibitory proteins for proteolysis, thereby triggering the separation of sister chromatids at the metaphase-to-anaphase transition. In late mitosis and in G1, degradation of CLB5 allows activation of the APC/C by CDH1, which is needed to destroy CDC20 and the B-type cyclin CLB2 to allow exit from mitosis and creating the low CDK state necessary for cytokinesis and for reforming prereplicative complexes in G1 prior to another round of replication., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 20, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLB5", "ec_number_list": "", "go_molecular_function": "GO:0030332 cyclin binding;GO:0140767 enzyme-substrate adaptor activity", "go_cellular_component": "GO:0000776 kinetochore;GO:0005680 anaphase-promoting complex", "go_biological_process": "GO:0051301 cell division;GO:0007346 regulation of mitotic cell cycle;GO:0016567 protein ubiquitination;GO:0031145 anaphase-promoting complex-dependent catabolic process;GO:0045842 positive regulation of mitotic metaphase/anaphase transition", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P16522-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P16550-1", "uniprot_id": "APA1_YEAST", "mass": 36493.0, "length": 321, "protein_name": "Protein APA1", "gene_name": "APA1", "organism": "Yeast", "refseq_name": "bifunctional AP-4-A phosphorylase/ADP sulfurylase", "refseq_ac": "NP_009880", "gene_names_uniprotkb": "APA1; DTP; YCL50C", "gene_names_refseq": "APA1; DTP1", "protein_names_uniprotkb": "Protein APA1; 2.7.7.5; ADP-sulfurylase; ATP adenylyltransferase; Diadenosine tetraphosphate alpha,beta-phosphorylase (ADP-forming)", "protein_names_refseq": "bifunctional AP-4-A phosphorylase/ADP sulfurylase", "tax_id": 559292, "disease": "", "pathway": " (sce:YCL050C)", "pathway_count": 1, "publication_count": 24, "publication_id_list": "14562095;14562106;1574125;1660456;17330950;17563356;18407956;19779198;19795423;19823750;21177495;2174812;2174863;23628156;23749301;24374639;24909858;2556364;2840953;2982863;3009435;33481703;33491328;7642617", "class_list": "", "function": "Ap4A phosphorylase catalyzes the phosphorolytic degradation of bis(5'-adenosyl) tetraphosphate (Ap4A) into ADP and ATP. Can also use other Np4N' nucleotides (where N and N' stand for A,C,G or U) as substrates with equal efficiency. Cannot catalyze the reverse reaction. Additionally, this enzyme can also catalyze the phosphorolytic degradation of adenosine 5'-phosphosulfate (AMPS) into ADP and sulfate, the reversible exchange reaction between inorganic phosphate and the beta-phosphate of a nucleoside diphosphate (NDP), and the synthesis of Ap4A from AMPS plus ATP., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQW6", "ec_number_list": "2.7.7.5;2.7.7.53", "go_molecular_function": "GO:0005524 ATP binding;GO:0003877 ATP:ADP adenylyltransferase activity;GO:0008796 bis(5'-nucleosyl)-tetraphosphatase activity;GO:0004780 sulfate adenylyltransferase (ADP) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0009165 nucleotide biosynthetic process;GO:0009164 nucleoside catabolic process", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "P16550-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P16603-1", "uniprot_id": "NCPR_YEAST", "mass": 76772.0, "length": 691, "protein_name": "NADPH--cytochrome P450 reductase", "gene_name": "NCP1", "organism": "Yeast", "refseq_name": "NADPH--hemoprotein reductase", "refseq_ac": "NP_011908", "gene_names_uniprotkb": "NCP1; CPR1; NCPR1; PRD1", "gene_names_refseq": "CPR1; NCP1", "protein_names_uniprotkb": "NADPH--cytochrome P450 reductase; 1.6.2.4; CPR; P450R", "protein_names_refseq": "NADPH--hemoprotein reductase", "tax_id": 559292, "disease": "Antley-Bixler syndrome with disordered steroidogenesis (Disease Ontology:DOID:0050462); congenital adrenal hyperplasia (Disease Ontology:DOID:0050811); cytochrome P450 oxidoreductase deficiency (Disease Ontology:DOID:0080925)", "pathway": " (sce:YHR042W); (R-SCE-1222556); (R-SCE-1474151); (R-SCE-203615); (R-SCE-392154); (R-SCE-5218920); (R-SCE-5578775); (R-SCE-9009391); (R-SCE-9033241); (R-SCE-9856530)", "pathway_count": 10, "publication_count": 22, "publication_id_list": "11485306;14557538;14562095;14562106;14576278;15082539;16407065;16407407;1730736;17322287;19483672;19779198;20557022;22106047;24374639;3139648;32597660;33481703;33491328;8091229;9368374;9468503", "class_list": "", "function": "This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. Has NADPH-dependent ferrireductase activity on the plasma membrane., [UniProtKB, HAMAP, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D3DKZ0", "ec_number_list": "2.7.11.11;2.7.11.1;1.11.1.6;1.6.2.4;1.1.1.42;2.7.11.13;1.3.1.124;2.3.1.7;7.2.2.10;4.1.2.63;3.1.2.2;2.3.1.225;2.3.2.27;5.3.3.8;3.4.24.-;3.1.2.22;3.1.2.-;3.6.1.-;3.6.1.56;3.6.1.77", "go_molecular_function": "GO:0009055 electron transfer activity;GO:0050660 flavin adenine dinucleotide binding;GO:0010181 FMN binding;GO:0050661 NADP binding;GO:0003958 NADPH-hemoprotein reductase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006696 ergosterol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "P16603-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P16622-1", "uniprot_id": "HEMH_YEAST", "mass": 44596.0, "length": 393, "protein_name": "Ferrochelatase, mitochondrial", "gene_name": "HEM15", "organism": "Yeast", "refseq_name": "ferrochelatase HEM15", "refseq_ac": "NP_014819", "gene_names_uniprotkb": "HEM15", "gene_names_refseq": "HEM15", "protein_names_uniprotkb": "Ferrochelatase, mitochondrial; 4.98.1.1; Heme synthase; Protoheme ferro-lyase", "protein_names_refseq": "ferrochelatase HEM15", "tax_id": 559292, "disease": "erythropoietic protoporphyria (Disease Ontology:DOID:13270); cutaneous porphyria (Disease Ontology:DOID:13271); cancer (Disease Ontology:DOID:162); colon adenocarcinoma (Disease Ontology:DOID:234)", "pathway": " (sce:YOR176W); (R-SCE-189451); (R-SCE-9837999)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "14562106;17563356;2185242;2235498;23749301;24374639;3042776;32597660;33481703;33491328;9169874", "class_list": "", "function": "Catalyzes the ferrous insertion into protoporphyrin IX., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2N2", "ec_number_list": "3.5.3.1;7.1.2.2;2.3.3.1;4.2.1.2;3.6.4.10;4.98.1.1;4.2.1.3;1.2.4.2;1.1.1.37;1.2.4.1;3.4.21.53;2.3.1.41;1.2.1.4;1.2.1.5;6.1.1.5;2.3.3.10", "go_molecular_function": "GO:0004325 ferrochelatase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006783 heme biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P16622-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P16649-1", "uniprot_id": "TUP1_YEAST", "mass": 78308.0, "length": 713, "protein_name": "General transcriptional corepressor TUP1", "gene_name": "TUP1", "organism": "Yeast", "refseq_name": "chromatin-silencing transcriptional regulator TUP1", "refseq_ac": "NP_010007", "gene_names_uniprotkb": "TUP1; AAR1; AER2; AMM1; CYC9; FLK1; SFL2; UMR7; YCR84C", "gene_names_refseq": "AAR1; AER2; AMM1; CRT4; CYC9; FLK1; ROX4; SFL2; TUP1; UMR7", "protein_names_uniprotkb": "General transcriptional corepressor TUP1; Flocculation suppressor protein; Glucose repression regulatory protein TUP1; Repressor AER2", "protein_names_refseq": "chromatin-silencing transcriptional regulator TUP1", "tax_id": 559292, "disease": "", "pathway": " (sce:YCR084C)", "pathway_count": 1, "publication_count": 36, "publication_id_list": "10722672;10856245;11069890;11172717;11230135;11500510;11784848;14525981;14562095;14562106;14665463;15665377;1574125;17330950;18407956;1900249;1901558;19779198;19795423;19823750;20702584;21126336;2197185;2247069;22814378;23749301;24374639;30516470;32597660;33229814;33481703;33491328;7995523;8675011;8943325;9741624", "class_list": "", "function": "Acts as a component of the CYC8-TUP1 corepressor complex which is involved in the repression of many genes in a wide variety of physiological processes including heme-regulated and catabolite repressed genes. May also be involved in the derepression of at least some target genes. The complex is recruited to target genes by interaction with DNA-bound transcriptional repressors, like MATALPHA2, MIG1, RFX1 and SKO1. The complex recruits histone deacetylases to produce a repressive chromatin structure, interacts with hypoacetylated N-terminal tails of histones H3 and H4 that have been programmed for repression by the action of histone deacetylases and interferes directly with the transcriptional machinery by associating with the RNA polymerase II mediator complex., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 6, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 6, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 6, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 27, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "D6VR85;P17995;P18323", "ec_number_list": "", "go_molecular_function": "GO:0003714 transcription corepressor activity;GO:0042826 histone deacetylase binding;GO:0080025 phosphatidylinositol-3,5-bisphosphate binding;GO:0042393 histone binding;GO:1990756 ubiquitin-like ligase-substrate adaptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0017053 transcription repressor complex;GO:0019005 SCF ubiquitin ligase complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0000278 mitotic cell cycle;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 4.4, "record_id": "P16649-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P16658-1", "uniprot_id": "SEN2_YEAST", "mass": 44109.0, "length": 377, "protein_name": "tRNA-splicing endonuclease subunit SEN2", "gene_name": "SEN2", "organism": "Yeast", "refseq_name": "tRNA splicing endonuclease subunit SEN2", "refseq_ac": "NP_013206", "gene_names_uniprotkb": "SEN2; L8004.12", "gene_names_refseq": "SEN2", "protein_names_uniprotkb": "tRNA-splicing endonuclease subunit SEN2; 4.6.1.16; Splicing endonuclease protein 2; tRNA-intron endonuclease SEN2", "protein_names_refseq": "tRNA splicing endonuclease subunit SEN2", "tax_id": 559292, "disease": "pontocerebellar hypoplasia type 2B (Disease Ontology:DOID:0060268)", "pathway": " (sce:YLR105C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "12925762;14562106;16823961;2182322;2211694;23749301;24374639;33491328;9169871;9200603", "class_list": "", "function": "Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. This subunit may anchor the endonuclease complex to the nuclear membrane. Probably carries the active site for 5'-splice site cleavage., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYA5", "ec_number_list": "", "go_molecular_function": "GO:0003676 nucleic acid binding;GO:0000213 tRNA-intron lyase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0005777 peroxisome;GO:0012505 endomembrane system", "go_biological_process": "GO:0008033 tRNA processing;GO:0000379 tRNA-type intron splice site recognition and cleavage", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P16658-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P16661-1", "uniprot_id": "ALG1_YEAST", "mass": 51929.0, "length": 449, "protein_name": "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "gene_name": "ALG1", "organism": "Yeast", "refseq_name": "chitobiosyldiphosphodolichol beta-1,4 mannosyltransferase", "refseq_ac": "NP_009668", "gene_names_uniprotkb": "ALG1; YBR0906", "gene_names_refseq": "ALG1", "protein_names_uniprotkb": "Chitobiosyldiphosphodolichol beta-mannosyltransferase; 2.4.1.142; Asparagine-linked glycosylation protein 1; Beta-1,4-mannosyltransferase; GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase; GDP-mannose-dolichol diphosphochitobiose mannosyltransferase", "protein_names_refseq": "chitobiosyldiphosphodolichol beta-1,4 mannosyltransferase", "tax_id": 559292, "disease": "congenital disorder of glycosylation type I (Disease Ontology:DOID:0050570); congenital disorder of glycosylation Ik (Disease Ontology:DOID:0080563); congenital disorder of glycosylation (Disease Ontology:DOID:5212)", "pathway": " (sce:YBR110W); (R-SCE-446193)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "14562095;14562106;15044395;2182636;24374639;29939232;7813418;7900426", "class_list": "", "function": "Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQA9", "ec_number_list": "2.4.1.142", "go_molecular_function": "GO:0000030 mannosyltransferase activity;GO:0004578 chitobiosyldiphosphodolichol beta-mannosyltransferase activity;GO:0019187 beta-1,4-mannosyltransferase activity", "go_cellular_component": "GO:0098554 cytoplasmic side of endoplasmic reticulum membrane;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0006488 dolichol-linked oligosaccharide biosynthetic process;GO:0006487 protein N-linked glycosylation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P16661-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P16861-1", "uniprot_id": "PFKA1_YEAST", "mass": 107970.0, "length": 987, "protein_name": "ATP-dependent 6-phosphofructokinase subunit alpha", "gene_name": "PFK1", "organism": "Yeast", "refseq_name": "6-phosphofructokinase subunit alpha", "refseq_ac": "NP_011756", "gene_names_uniprotkb": "PFK1; G8599", "gene_names_refseq": "PFK1", "protein_names_uniprotkb": "ATP-dependent 6-phosphofructokinase subunit alpha; 2.7.1.11; ATP-PFK; ATP-dependent 6-phosphofructokinase; Phosphofructokinase 1; Phosphohexokinase", "protein_names_refseq": "6-phosphofructokinase subunit alpha", "tax_id": 559292, "disease": "disease of metabolism (Disease Ontology:DOID:0014667); glycogen storage disease VII (Disease Ontology:DOID:11721); glycogen storage disease (Disease Ontology:DOID:2747)", "pathway": " (sce:YGR240C); (R-SCE-6798695); (R-SCE-70171)", "pathway_count": 3, "publication_count": 40, "publication_id_list": "11221662;14562106;145942;147195;15665377;16962558;17330950;17563356;18313953;18407956;19473;19684113;19779198;20190278;20702584;21126336;21177495;21241708;22106047;22218487;22814378;23749301;2408613;24374639;2528496;3000145;3007939;30516470;32597660;33481703;33491328;6211191;6219673;6458303;8132627;8223596;8663166;8701610;9090057;9169869", "class_list": "", "function": "Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis., [UniProtKB, HAMAP, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 48, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VV20", "ec_number_list": "2.7.1.40;5.4.2.11;2.7.1.1;4.2.1.24;3.6.4.13;2.4.1.1;3.4.23.25;3.6.4.10;5.3.1.9;5.1.3.-;5.2.1.8;1.11.1.6;3.5.4.6;2.7.1.11;2.7.1.2;1.1.1.42;3.4.25.1;3.6.4.6;3.6.5.-;2.7.11.24;3.6.4.12;5.4.2.2;1.11.1.24;2.7.4.6;2.4.1.186;1.1.1.205;2.7.1.35;3.4.19.12;2.4.2.7;5.4.2.7;2.3.2.26;2.7.11.23;2.4.2.1;2.7.1.59;3.5.4.5;3.4.11.-;3.3.2.10", "go_molecular_function": "GO:0070095 fructose-6-phosphate binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0003872 6-phosphofructokinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0005945 6-phosphofructokinase complex", "go_biological_process": "GO:0006096 glycolytic process;GO:0030388 fructose 1,6-bisphosphate metabolic process;GO:0061621 canonical glycolysis;GO:0051453 regulation of intracellular pH;GO:0006002 fructose 6-phosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 4.1, "record_id": "P16861-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P16862-1", "uniprot_id": "PFKA2_YEAST", "mass": 104618.0, "length": 959, "protein_name": "ATP-dependent 6-phosphofructokinase subunit beta", "gene_name": "PFK2", "organism": "Yeast", "refseq_name": "6-phosphofructokinase subunit beta", "refseq_ac": "NP_013932", "gene_names_uniprotkb": "PFK2; YM8325.06C", "gene_names_refseq": "PFK2", "protein_names_uniprotkb": "ATP-dependent 6-phosphofructokinase subunit beta; 2.7.1.11; ATP-PFK; ATP-dependent 6-phosphofructokinase; Phosphofructokinase 2; Phosphohexokinase", "protein_names_refseq": "6-phosphofructokinase subunit beta", "tax_id": 559292, "disease": "disease of metabolism (Disease Ontology:DOID:0014667); glycogen storage disease VII (Disease Ontology:DOID:11721); glycogen storage disease (Disease Ontology:DOID:2747)", "pathway": " (sce:YMR205C); (R-SCE-6798695); (R-SCE-70171)", "pathway_count": 3, "publication_count": 41, "publication_id_list": "11221662;11724581;11875433;14562106;145942;15665377;16962558;17287358;17330950;17563356;18313953;18407956;19473;19684113;19779198;19795423;19823750;20702584;21126336;21177495;21241708;22218487;23149688;23749301;2408613;24374639;2528496;3000145;3007939;30516470;32597660;33481703;33491328;40590;6211191;6219673;6458303;8132627;8223596;8663166;9169872", "class_list": "", "function": "Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis., [UniProtKB, HAMAP, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 43, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W030", "ec_number_list": "2.7.1.40;5.4.2.11;2.7.1.1;4.2.1.24;3.6.4.13;2.4.1.1;3.4.23.25;3.6.4.10;5.3.1.9;5.1.3.-;5.2.1.8;1.11.1.6;3.5.4.6;2.7.1.11;2.7.1.2;1.1.1.42;3.4.25.1;3.6.4.6;3.6.5.-;2.7.11.24;3.6.4.12;5.4.2.2;1.11.1.24;2.7.4.6;2.4.1.186;1.1.1.205;2.7.1.35;3.4.19.12;2.4.2.7;5.4.2.7;2.3.2.26;2.7.11.23;2.4.2.1;2.7.1.59;3.5.4.5;3.4.11.-;3.3.2.10", "go_molecular_function": "GO:0070095 fructose-6-phosphate binding;GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0003872 6-phosphofructokinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0005945 6-phosphofructokinase complex", "go_biological_process": "GO:0006096 glycolytic process;GO:0030388 fructose 1,6-bisphosphate metabolic process;GO:0061621 canonical glycolysis;GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly;GO:0051453 regulation of intracellular pH", "synthesized_glycan_count": 0, "hit_score": 4.2, "record_id": "P16862-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P17064-1", "uniprot_id": "FCY2_YEAST", "mass": 58201.0, "length": 533, "protein_name": "Purine-cytosine permease FCY2", "gene_name": "FCY2", "organism": "Yeast", "refseq_name": "purine-cytosine permease", "refseq_ac": "NP_010976", "gene_names_uniprotkb": "FCY2", "gene_names_refseq": "BRA7; FCY2", "protein_names_uniprotkb": "Purine-cytosine permease FCY2; Cytosine/purine transport protein FCY2; Fluorocytosine resistance protein 2; PCP FCY2", "protein_names_refseq": "purine-cytosine permease", "tax_id": 559292, "disease": "", "pathway": " (sce:YER056C)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "14562106;15665377;16847258;19779198;20702584;2191181;22106047;22814378;23749301;24374639;32597660;33481703;33491328;6300123;7762297;9169868", "class_list": "", "function": "This permease has a broad specificity towards purines, and also transport cytosine and 5-methylcytosine but neither uracil nor thymine., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLV9", "ec_number_list": "", "go_molecular_function": "GO:0015205 nucleobase transmembrane transporter activity;GO:0015212 cytidine transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0015861 cytidine transport;GO:0072530 purine-containing compound transmembrane transport;GO:0015856 cytosine transport", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P17064-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P17076-1", "uniprot_id": "RL8A_YEAST", "mass": 28125.0, "length": 256, "protein_name": "Large ribosomal subunit protein eL8A", "gene_name": "RPL8A", "organism": "Yeast", "refseq_name": "60S ribosomal protein eL8 RPL8A", "refseq_ac": "NP_011830", "gene_names_uniprotkb": "RPL8A; MAK7; RPL4A", "gene_names_refseq": "MAK7; RPL8A", "protein_names_uniprotkb": "Large ribosomal subunit protein eL8A; 60S ribosomal protein L8-A; L4-2; L4; L7a-1; Maintenance of killer protein 7; RP6; YL5", "protein_names_refseq": "60S ribosomal protein eL8 RPL8A", "tax_id": 559292, "disease": "", "pathway": " (sce:YHL033C)", "pathway_count": 1, "publication_count": 21, "publication_id_list": "10601260;11701127;14562095;14562106;14976550;1544921;17287358;17563356;18407956;2046660;21109664;2183194;22096102;23749301;24374639;24524803;33491328;7739558;787537;8091229;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DKT5", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005829 cytosol;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation;GO:0000470 maturation of LSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P17076-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P17106-1", "uniprot_id": "CBF1_YEAST", "mass": 39388.0, "length": 351, "protein_name": "Centromere-binding protein 1", "gene_name": "CBF1", "organism": "Yeast", "refseq_name": "Cbf1p", "refseq_ac": "NP_012594", "gene_names_uniprotkb": "CBF1; CEP1; CP1; CPF1; J1730", "gene_names_refseq": "CBF1; CEP1; CPF1", "protein_names_uniprotkb": "Centromere-binding protein 1; CBP-1; Centromere promoter factor 1; Centromere-binding factor 1", "protein_names_refseq": "Cbf1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR060W)", "pathway_count": 1, "publication_count": 32, "publication_id_list": "14562095;14562106;14576278;1549123;17322287;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20190278;21126336;21177495;2185892;2188087;22218487;2249662;22814378;23749301;24374639;24909858;30381292;30516470;32597660;33481703;33491328;8641269;8665859;8840504;9171357", "class_list": "", "function": "Required for chromosome stability and methionine prototrophy. It is involved in chromosomal segregation. Binds to a highly conserved DNA sequence (5'-RTCACRTG-3'), called CDEI, found in centromeres and in several promoters. DNA-binding activity is enhanced by MET28. Required as an auxiliary factor for transcriptional activation of sulfur metabolism together with MET4 and MET28., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 34, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWN1;P17623;Q6Q5N1", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0046983 protein dimerization activity;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0000775 chromosome, centromeric region;GO:0000776 kinetochore;GO:0089713 Cbf1-Met4-Met28 complex", "go_biological_process": "GO:1900060 negative regulation of ceramide biosynthetic process;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 3.3, "record_id": "P17106-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P17119-1", "uniprot_id": "KAR3_YEAST", "mass": 84004.0, "length": 729, "protein_name": "Kinesin-like protein KAR3", "gene_name": "KAR3", "organism": "Yeast", "refseq_name": "Kar3p", "refseq_ac": "NP_015467", "gene_names_uniprotkb": "KAR3; P9659.16", "gene_names_refseq": "KAR3; OSR11", "protein_names_uniprotkb": "Kinesin-like protein KAR3; 5.6.1.4; Nuclear fusion protein", "protein_names_refseq": "Kar3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR141C)", "pathway_count": 1, "publication_count": 29, "publication_id_list": "10087265;11387196;11729143;14562106;15846338;17287358;17382884;17563356;17620411;18079178;18407956;19520826;19779198;21126336;21177495;2138512;22734002;24374639;25313961;32597660;33481703;33491328;7912193;8106549;8224825;9169875;9334348;9485302;9859995", "class_list": "", "function": "Minus end-directed microtubule (MT) motor involved in spindle midzone assembly, poleward transport of newly captured kinetochores along the lateral side of MTs, karyogamy (nuclear fusion) during mating, and with an essential function in meiosis I (PubMed:11387196, PubMed:11729143, PubMed:17382884, PubMed:17620411, PubMed:22734002, PubMed:25313961, PubMed:7912193, PubMed:8106549, PubMed:9334348, PubMed:9859995). Functions together with the accessory proteins CIK1 or VIK1 (PubMed:10087265, PubMed:11729143, PubMed:15846338, PubMed:17382884, PubMed:22734002, PubMed:25313961). Drives the poleward transport of newly captured kinetochores along the lateral side of MTs, both during S-phase and during M-phase (PubMed:15846338, PubMed:17620411, PubMed:18079178). To contribute to spindle midzone assembly during mitotic metaphase, the nuclear KAR3-CIK1 motor cross-links anti-parallel microtubules to align them on the spindle axis; as the motor travels polewards splayed microtubules are pulled into alignment (PubMed:25313961). During the karyogamy (nuclear fusion) step of mating, KAR3-CIK1 cross-links antiparallel cytoplasmic microtubules emanating from the spindle pole bodies of mating partners; the motor activity of KAR3 creates the force that pulls the nuclei together by sliding cross-linked microtubules past one another (PubMed:2138512, PubMed:8106549). KAR3-CIK1 promotes microtubule shortening predominantly from the microtubule plus-end (PubMed:17382884). Together with cytoplasmic VIK1, may act to stabilize microtubules (PubMed:17382884). Requires accessory protein VIK1 for spindle pole body localization and to allow the CIN8 and KIP1 motors to generate outwardly directed spindle forces (PubMed:11729143, PubMed:2138512, PubMed:7912193, PubMed:8224825). Essential during meiosis I (PubMed:9334348). The ATPase activity is stimulated by microtubule-binding (PubMed:11387196, PubMed:22734002, PubMed:9859995)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 17, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W4D9", "ec_number_list": "3.6.4.13;5.6.2.3;3.6.4.10;3.6.-.-;5.6.2.4;3.6.4.-;5.6.1.4;3.6.4.12;3.6.4.6;5.6.2.5;3.6.1.-;2.3.2.27;3.1.-.-;3.4.24.-;3.6.5.-;2.7.4.3;2.7.11.1;7.2.2.-", "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0016887 ATP hydrolysis activity;GO:0008569 minus-end-directed microtubule motor activity", "go_cellular_component": "GO:0000922 spindle pole;GO:0005634 nucleus;GO:0005874 microtubule;GO:0015630 microtubule cytoskeleton;GO:0005694 chromosome", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0051301 cell division;GO:0036503 ERAD pathway;GO:0060236 regulation of mitotic spindle organization;GO:0051256 mitotic spindle midzone assembly", "synthesized_glycan_count": 0, "hit_score": 3.0, "record_id": "P17119-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P17214-1", "uniprot_id": "EST1_YEAST", "mass": 81800.0, "length": 699, "protein_name": "Telomere elongation protein EST1", "gene_name": "EST1", "organism": "Yeast", "refseq_name": "Est1p", "refseq_ac": "NP_013334", "gene_names_uniprotkb": "EST1; L8083.15", "gene_names_refseq": "EST1", "protein_names_uniprotkb": "Telomere elongation protein EST1; Ever shorter telomeres protein 1", "protein_names_refseq": "Est1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR233C); (R-SCE-975957)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "11390652;1669287;17245108;21126336;2406024;24374639;2655926;33491328;9169871", "class_list": "", "function": "Directly involved in telomere replication. Associates with telomerase and during its interaction with CDC13, telomerase activity is promoted., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYN3;Q05997", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0042162 telomeric DNA binding;GO:0003697 single-stranded DNA binding;GO:0070034 telomerase RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005697 telomerase holoenzyme complex;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0000723 telomere maintenance;GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0032210 regulation of telomere maintenance via telomerase;GO:0007004 telomere maintenance via telomerase;GO:0071919 G-quadruplex DNA formation", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P17214-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P17255-1", "uniprot_id": "VATA_YEAST", "mass": 118637.0, "length": 1071, "protein_name": "V-type proton ATPase catalytic subunit A", "gene_name": "VMA1", "organism": "Yeast", "refseq_name": "H(+)-transporting V1 sector ATPase subunit A", "refseq_ac": "NP_010096", "gene_names_uniprotkb": "VMA1; CLS8; D1286; TFP1", "gene_names_refseq": "CLS8; TFP1; VMA1", "protein_names_uniprotkb": "V-type proton ATPase catalytic subunit A; 7.1.2.2; Sce VMA intein; V-ATPase subunit A; VDE; VMA1-derived endonuclease; Vacuolar proton pump subunit A", "protein_names_refseq": "H(+)-transporting V1 sector ATPase subunit A", "tax_id": 559292, "disease": "autosomal recessive cutis laxa type IID (Disease Ontology:DOID:0070129); developmental and epileptic encephalopathy 93 (Disease Ontology:DOID:0112275)", "pathway": " (sce:YDL185W); (R-SCE-1222556); (R-SCE-77387); (R-SCE-917977); (R-SCE-9639288)", "pathway_count": 5, "publication_count": 35, "publication_id_list": "10644733;10828056;11283612;11884132;12235380;1417861;14562095;14562106;15335920;1534148;15665377;1656215;17287358;18055462;18407956;19779198;20702584;21126336;2139027;2146742;22218487;22814378;23749301;24374639;25971514;27295975;2905423;32597660;33481703;33491328;34965436;8508780;8533471;9160747;9169867", "class_list": "", "function": "Catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:18055462, PubMed:2139027). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (PubMed:18055462, PubMed:2139027)., [UniProtKB, PubMed, PubMed]; PI-SceI is an endonuclease that can cleave at a site present in a VMA1 allele that lacks the derived endonuclease segment of the open reading frame; cleavage at this site only occurs during meiosis and initiates 'homing', a genetic event that converts a VMA1 allele lacking VDE into one that contains it., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 54, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRG7;O74301;Q9Y7W5", "ec_number_list": "7.1.2.2;3.1.-.-;3.6.5.-;2.7.1.67;2.7.11.1", "go_molecular_function": "GO:0003677 DNA binding;GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0004519 endonuclease activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0046034 ATP metabolic process;GO:0048388 endosomal lumen acidification;GO:0007035 vacuolar acidification;GO:1902600 proton transmembrane transport;GO:0016539 intein-mediated protein splicing", "synthesized_glycan_count": 0, "hit_score": 3.6, "record_id": "P17255-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P17442-1", "uniprot_id": "PHO81_YEAST", "mass": 134029.0, "length": 1178, "protein_name": "Phosphate system positive regulatory protein PHO81", "gene_name": "PHO81", "organism": "Yeast", "refseq_name": "Pho81p", "refseq_ac": "NP_011749", "gene_names_uniprotkb": "PHO81; G8567", "gene_names_refseq": "PHO81; VAC6", "protein_names_uniprotkb": "Phosphate system positive regulatory protein PHO81; CDK inhibitor PHO81", "protein_names_refseq": "Pho81p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR233C); (R-SCE-204005); (R-SCE-3295583); (R-SCE-983168)", "pathway_count": 4, "publication_count": 22, "publication_id_list": "11069666;14562095;14562106;15057567;15127225;17563356;18407956;19779198;20190278;20489023;2186378;22814378;23749301;24374639;33481703;33491328;7939631;7957107;8492812;8493108;8701610;9169869", "class_list": "", "function": "Inhibits the kinase activity of the cyclin-CDKs PHO80-PHO85 and PCL7-PHO85 under low-phosphate conditions., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 26, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VV13;Q06887", "ec_number_list": "", "go_molecular_function": "GO:0008081 phosphoric diester hydrolase activity;GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0006796 phosphate-containing compound metabolic process;GO:0016036 cellular response to phosphate starvation;GO:0000425 pexophagy", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "P17442-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P17629-1", "uniprot_id": "HPR1_YEAST", "mass": 87829.0, "length": 752, "protein_name": "THO complex subunit HPR1", "gene_name": "HPR1", "organism": "Yeast", "refseq_name": "Hpr1p", "refseq_ac": "NP_010422", "gene_names_uniprotkb": "HPR1; YD9302.14", "gene_names_refseq": "HPR1; TRF1", "protein_names_uniprotkb": "THO complex subunit HPR1; Hyperrecombination protein 1", "protein_names_refseq": "Hpr1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR138W)", "pathway_count": 1, "publication_count": 24, "publication_id_list": "11060033;11979277;12093753;12871933;14527416;14562095;14562106;15192704;17330950;17563356;18407956;19779198;19795423;19823750;20190278;20702584;2181275;23749301;24374639;30516470;32597660;33481703;33491328;9169867", "class_list": "", "function": "Component the THO subcomplex of the TREX complex, which operates in coupling transcription elongation to mRNA export. The THO complex is recruited to transcribed genes and moves along the gene with the elongating polymerase during transcription. THO is important for stabilizing nascent RNA in the RNA polymerase II elongation complex by preventing formation of DNA:RNA hybrids behind the elongating polymerase. It functions in cotranscriptional formation of an export-competent messenger ribonucleoprotein particle (mRNP) by facilitating the loading of ATP-dependent RNA helicase SUB2 and the mRNA export factor YRA1 along the nascent mRNA., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSC1;Q03918", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0000445 THO complex part of transcription export complex;GO:0016593 Cdc73/Paf1 complex;GO:0000781 chromosome, telomeric region;GO:0000446 nucleoplasmic THO complex", "go_biological_process": "GO:0006310 DNA recombination;GO:0006406 mRNA export from nucleus;GO:0006368 transcription elongation by RNA polymerase II;GO:0006283 transcription-coupled nucleotide-excision repair;GO:0045943 positive regulation of transcription by RNA polymerase I", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "P17629-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P17649-1", "uniprot_id": "GABAT_YEAST", "mass": 52946.0, "length": 471, "protein_name": "4-aminobutyrate aminotransferase", "gene_name": "UGA1", "organism": "Yeast", "refseq_name": "4-aminobutyrate transaminase", "refseq_ac": "NP_011533", "gene_names_uniprotkb": "UGA1", "gene_names_refseq": "UGA1", "protein_names_uniprotkb": "4-aminobutyrate aminotransferase; 2.6.1.19; GABA aminotransferase; GABA transaminase; GABA-AT; Gamma-amino-N-butyrate transaminase", "protein_names_refseq": "4-aminobutyrate transaminase", "tax_id": 559292, "disease": "West syndrome (Disease Ontology:DOID:0050562); GABA aminotransferase deficiency (Disease Ontology:DOID:0060174); Parkinsonism (Disease Ontology:DOID:0080855); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); Huntington's disease (Disease Ontology:DOID:12858); depressive disorder (Disease Ontology:DOID:1596); status epilepticus (Disease Ontology:DOID:1824); epilepsy (Disease Ontology:DOID:1826); reflex epilepsy (Disease Ontology:DOID:2548); ischemia (Disease Ontology:DOID:326); heroin dependence (Disease Ontology:DOID:9976)", "pathway": " (sce:YGR019W); (R-SCE-916853)", "pathway_count": 2, "publication_count": 14, "publication_id_list": "11914276;14562106;17322287;17355287;18407956;19411412;2190186;24374639;32597660;33481703;33491328;3888627;9169869;9290212", "class_list": "", "function": "Required for the degradation of gamma-aminobutyric acid (GABA), which is important for utilization of GABA as nitrogen source and for oxidative stress tolerance. Deaminates GABA to succinate semialdehyde, which in turn is converted to succinate by the succinate-semialdehyde dehydrogenase UGA2. Cannot transaminate beta-alanine (BAL)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 12, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A5H0J7;D6VUF4", "ec_number_list": "2.6.1.19", "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0034386 4-aminobutyrate:2-oxoglutarate transaminase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0009450 gamma-aminobutyric acid catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P17649-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P17695-1", "uniprot_id": "GLRX2_YEAST", "mass": 15861.0, "length": 143, "protein_name": "Glutaredoxin-2", "gene_name": "GRX2", "organism": "Yeast", "refseq_name": "dithiol glutaredoxin GRX2", "refseq_ac": "NP_010801", "gene_names_uniprotkb": "GRX2; D9719.17; TTR1; TTR", "gene_names_refseq": "GRX2; TTR1", "protein_names_uniprotkb": "Glutaredoxin-2; 1.11.1.9; 2.5.1.18; Glutathione-dependent oxidoreductase 2; Thioltransferase", "protein_names_refseq": "dithiol glutaredoxin GRX2", "tax_id": 559292, "disease": "Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (sce:YDR513W)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "10786615;11875065;11958675;12684511;14562106;1530649;16606613;17322287;18407956;18992757;19779198;19795423;19823750;20036764;20417731;21565288;2189409;24374639;27821475;33481703;33491328;9169867;9571241", "class_list": "", "function": "Component of the glutathione system which performs several activities such as glutathione-dependent oxidoreductase, glutathione peroxidase and glutathione S-transferase (GST) activity (PubMed:11875065, PubMed:12684511). The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing cytosolic protein- and non-protein-disulfides in a coupled system with glutathione reductase. Required for resistance to reactive oxygen species (ROS) by directly reducing hydroperoxides and for the detoxification of ROS-mediated damage. GRX2 is more active as an oxidoreductase than GRX1 (PubMed:18992757, PubMed:20417731, PubMed:9571241). Responsible for the S-glutathionylation of DHBP synthase (PubMed:21565288)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTD4;Q6B234", "ec_number_list": "1.11.1.9;2.5.1.18;1.8.4.-;1.11.1.24;1.8.5.1", "go_molecular_function": "GO:0004364 glutathione transferase activity;GO:0015036 disulfide oxidoreductase activity;GO:0015038 glutathione disulfide oxidoreductase activity;GO:0004602 glutathione peroxidase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0034599 cellular response to oxidative stress;GO:0006749 glutathione metabolic process", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P17695-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P17709-1", "uniprot_id": "HXKG_YEAST", "mass": 55377.0, "length": 500, "protein_name": "Glucokinase-1", "gene_name": "GLK1", "organism": "Yeast", "refseq_name": "glucokinase", "refseq_ac": "NP_009890", "gene_names_uniprotkb": "GLK1; HOR3; YCL312; YCL40W", "gene_names_refseq": "GLK1; HOR3", "protein_names_uniprotkb": "Glucokinase-1; 2.7.1.2; GLK-1; Glucose kinase 1", "protein_names_refseq": "glucokinase", "tax_id": 559292, "disease": "maturity-onset diabetes of the young (Disease Ontology:DOID:0050524); congenital nonspherocytic hemolytic anemia 5 (Disease Ontology:DOID:0051006); permanent neonatal diabetes mellitus (Disease Ontology:DOID:0060639); retinitis pigmentosa 92 (Disease Ontology:DOID:0061107); retinitis pigmentosa 79 (Disease Ontology:DOID:0061108); familial hyperinsulinemic hypoglycemia 3 (Disease Ontology:DOID:0070216); Charcot-Marie-Tooth disease type 4G (Disease Ontology:DOID:0110196); maturity-onset diabetes of the young type 2 (Disease Ontology:DOID:0111100); retinitis pigmentosa (Disease Ontology:DOID:10584); hypertension (Disease Ontology:DOID:10763); sickle cell anemia (Disease Ontology:DOID:10923); gestational diabetes (Disease Ontology:DOID:11714); neonatal diabetes mellitus (Disease Ontology:DOID:11717); hyperinsulinemic hypoglycemia (Disease Ontology:DOID:13317); hyperinsulinism (Disease Ontology:DOID:2018); anemia (Disease Ontology:DOID:2355); congenital nonspherocytic hemolytic anemia (Disease Ontology:DOID:2861); coronary artery disease (Disease Ontology:DOID:3393); glucose metabolism disease (Disease Ontology:DOID:4194); hyperglycemia (Disease Ontology:DOID:4195); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352); steatotic liver disease (Disease Ontology:DOID:9452); multiple myeloma (Disease Ontology:DOID:9538); acute lymphoblastic leukemia (Disease Ontology:DOID:9952); obesity (Disease Ontology:DOID:9970); hypoglycemia (Disease Ontology:DOID:9993)", "pathway": " (sce:YCL040W); (R-SCE-170822); (R-SCE-446205); (R-SCE-6798695); (R-SCE-70171)", "pathway_count": 5, "publication_count": 14, "publication_id_list": "14562106;1523890;15665377;1574125;18407956;19795423;19823750;22218487;22814378;24374639;30516470;3072253;33481703;33491328", "class_list": "", "function": "Two isoenzymes, hexokinase-1 and hexokinase-2, can phosphorylate keto- and aldohexoses in yeast, whereas a third isoenzyme, GLK, is specific for aldohexoses. All glucose phosphorylating enzymes are involved in glucose uptake., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 17, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 27, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQX5", "ec_number_list": "2.7.1.40;5.4.2.11;2.7.1.1;4.2.1.24;3.6.4.13;2.4.1.1;3.4.23.25;3.6.4.10;5.3.1.9;5.1.3.-;5.2.1.8;1.11.1.6;3.5.4.6;2.7.1.11;2.7.1.2;1.1.1.42;3.4.25.1;3.6.4.6;3.6.5.-;2.7.11.24;3.6.4.12;5.4.2.2;1.11.1.24;2.7.4.6;2.4.1.186;1.1.1.205;2.7.1.35;3.4.19.12;2.4.2.7;5.4.2.7;2.3.2.26;2.7.11.23;2.4.2.1;2.7.1.59;3.5.4.5;3.4.11.-;3.3.2.10", "go_molecular_function": "GO:0004340 glucokinase activity;GO:0008865 fructokinase activity;GO:0005524 ATP binding;GO:0005536 D-glucose binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0006006 glucose metabolic process;GO:0001678 intracellular glucose homeostasis;GO:0006096 glycolytic process;GO:0006013 mannose metabolic process;GO:0051156 glucose 6-phosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P17709-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P17883-1", "uniprot_id": "SKI3_YEAST", "mass": 163726.0, "length": 1432, "protein_name": "Superkiller protein 3", "gene_name": "SKI3", "organism": "Yeast", "refseq_name": "SKI complex subunit tetratricopeptide repeat protein SKI3", "refseq_ac": "NP_015515", "gene_names_uniprotkb": "SKI3; P9677.7", "gene_names_refseq": "SKI3; SKI5", "protein_names_uniprotkb": "Superkiller protein 3", "protein_names_refseq": "SKI complex subunit tetratricopeptide repeat protein SKI3", "tax_id": 559292, "disease": "trichohepatoenteric syndrome 1 (Disease Ontology:DOID:0111415)", "pathway": " (sce:YPR189W); (R-SCE-429958)", "pathway_count": 2, "publication_count": 18, "publication_id_list": "10744028;11532933;11720286;14562095;14562106;14671320;15044803;23749301;2404612;24374639;2660461;33491328;363683;6371496;7739552;7739557;9169875;9482746", "class_list": "", "function": "Component of the SKI complex involved in 3'-mRNA degradation pathway. Represses dsRNA virus propagation by specifically blocking translation of viral mRNAs, perhaps recognizing the absence of CAP or poly(A). Essential for cell growth only in the presence of M1 replicon., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q06585", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0055087 Ski complex;GO:0005634 nucleus", "go_biological_process": "GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay;GO:0070481 nuclear-transcribed mRNA catabolic process, non-stop decay;GO:0051607 defense response to virus;GO:0006402 mRNA catabolic process;GO:0000956 nuclear-transcribed mRNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P17883-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P17890-1", "uniprot_id": "RPC7_YEAST", "mass": 27724.0, "length": 251, "protein_name": "DNA-directed RNA polymerase III subunit RPC7", "gene_name": "RPC31", "organism": "Yeast", "refseq_name": "DNA-directed RNA polymerase III subunit C31", "refseq_ac": "NP_014248", "gene_names_uniprotkb": "RPC31; ACP2; N1769; RPC8", "gene_names_refseq": "ACP2; RPC31; RPC8", "protein_names_uniprotkb": "DNA-directed RNA polymerase III subunit RPC7; C31; DNA-directed RNA polymerase III 31 kDa polypeptide; RNA polymerase III subunit C7", "protein_names_refseq": "DNA-directed RNA polymerase III subunit C31", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL151C); (R-SCE-76061); (R-SCE-76066)", "pathway_count": 3, "publication_count": 19, "publication_id_list": "10384303;17330950;17563356;18407956;19779198;20702584;21126336;21177495;2201900;22218487;23749301;24374639;2835668;30516470;32597660;33481703;33491328;8686380;9169873", "class_list": "", "function": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. C31 is involved in the formation of the initiation complex., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W132;P20838", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0016779 nucleotidyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005666 RNA polymerase III complex", "go_biological_process": "GO:0042797 tRNA transcription by RNA polymerase III;GO:0006383 transcription by RNA polymerase III;GO:0006386 termination of RNA polymerase III transcription;GO:0006384 transcription initiation at RNA polymerase III promoter", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P17890-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P17891-1", "uniprot_id": "CLC1_YEAST", "mass": 26532.0, "length": 233, "protein_name": "Clathrin light chain", "gene_name": "CLC1", "organism": "Yeast", "refseq_name": "clathrin light chain CLC1", "refseq_ac": "NP_011683", "gene_names_uniprotkb": "CLC1", "gene_names_refseq": "CLC1; SCD4", "protein_names_uniprotkb": "Clathrin light chain; CLC", "protein_names_refseq": "clathrin light chain CLC1", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR167W); (R-SCE-190873); (R-SCE-196025); (R-SCE-432720); (R-SCE-437239); (R-SCE-8856828); (R-SCE-8866427); (R-SCE-8964038)", "pathway_count": 8, "publication_count": 14, "publication_id_list": "10069813;11084334;14562106;17322287;17330950;18407956;21126336;2211819;22218487;24374639;33481703;33491328;9169869;9290212", "class_list": "", "function": "Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. In yeast, it is involved in the retention of proteins in an intracellular membrane compartment, presumably the trans-Golgi. The yeast light chain is important for cell growth. The light chain may help to properly orient the assembly/ disassembly of the clathrin coats., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUV0", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005198 structural molecule activity;GO:0032050 clathrin heavy chain binding", "go_cellular_component": "GO:0030125 clathrin vesicle coat;GO:0005886 plasma membrane;GO:0005802 trans-Golgi network;GO:0030130 clathrin coat of trans-Golgi network vesicle;GO:0030132 clathrin coat of coated pit", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006897 endocytosis;GO:0048268 clathrin coat assembly;GO:0072583 clathrin-dependent endocytosis;GO:0045807 positive regulation of endocytosis", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P17891-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P17898-1", "uniprot_id": "CPT1_YEAST", "mass": 44829.0, "length": 393, "protein_name": "Cholinephosphotransferase 1", "gene_name": "CPT1", "organism": "Yeast", "refseq_name": "diacylglycerol cholinephosphotransferase", "refseq_ac": "NP_014269", "gene_names_uniprotkb": "CPT1; N1218; N1867", "gene_names_refseq": "CPT1", "protein_names_uniprotkb": "Cholinephosphotransferase 1; 2.7.8.2; Aminoalcohol phosphotransferase CPT1; CHOPT; Diacylglycerol cholinephosphotransferase 1; Sn-1,2-diacylglycerol cholinephosphotransferase", "protein_names_refseq": "diacylglycerol cholinephosphotransferase", "tax_id": 559292, "disease": "hereditary spastic paraplegia 81 (Disease Ontology:DOID:0112349); retinal disease (Disease Ontology:DOID:5679)", "pathway": " (sce:YNL130C); (R-SCE-1483191); (R-SCE-1483213)", "pathway_count": 3, "publication_count": 17, "publication_id_list": "12844361;14562095;14562106;15225629;1847919;19795423;19823750;2153142;24374639;3005242;3029130;7961445;7961735;7961831;8543066;8619318;9169873", "class_list": "", "function": "Catalyzes the final step in the CDP-choline route leading to phosphatidylcholin (PC). Preferentially uses CDP-monomethylethanolamine as aminoalcohol substrate. Shows highest activity toward di- and mono-unsaturated diacylglycerol species as lipid substrates. The CDP-choline pathway only contributes to net PC synthesis if exogenous choline is present. In its absence, this pathway recycles choline from PC turnover and may contribute to maintaining the proper PC species composition., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W152", "ec_number_list": "2.7.8.2;2.7.8.1", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004142 diacylglycerol cholinephosphotransferase activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006657 CDP-choline pathway", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P17898-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P17967-1", "uniprot_id": "PDI_YEAST", "mass": 58227.0, "length": 522, "protein_name": "Protein disulfide-isomerase", "gene_name": "PDI1", "organism": "Yeast", "refseq_name": "protein disulfide isomerase PDI1", "refseq_ac": "NP_009887", "gene_names_uniprotkb": "PDI1; MFP1; TRG1; YCL313; YCL43C", "gene_names_refseq": "MFP1; PDI1; TRG1", "protein_names_uniprotkb": "Protein disulfide-isomerase; 5.3.4.1; PDI; Thioredoxin-related glycoprotein 1", "protein_names_refseq": "protein disulfide isomerase PDI1", "tax_id": 559292, "disease": "asphyxia neonatorum (Disease Ontology:DOID:11088); autoimmune hepatitis (Disease Ontology:DOID:2048); post-traumatic stress disorder (Disease Ontology:DOID:2055); liver cirrhosis (Disease Ontology:DOID:5082); pulmonary hypertension (Disease Ontology:DOID:6432); irritable bowel syndrome (Disease Ontology:DOID:9778)", "pathway": " (sce:YCL043C); (R-SCE-901042)", "pathway_count": 2, "publication_count": 18, "publication_id_list": "1523890;1574125;16002399;16413482;1761235;1761527;1761554;1840696;18815132;19124653;2063627;21700223;23749301;24374639;32597660;33481703;33491328;39930008", "class_list": "", "function": "Protein disulfide isomerase of ER lumen required for formation of disulfide bonds in secretory and cell-surface proteins and which unscrambles non-native disulfide bonds (PubMed:16002399, PubMed:1761554, PubMed:18815132, PubMed:19124653, PubMed:21700223). Forms a complex with MNL1 to process unfolded protein-bound Man8GlcNAc2 oligosaccharides to Man7GlcNAc2, promoting degradation in unfolded protein response. The MNL1-PDI1 complex initiates ERAD by performing two crucial reactions on glycoprotein substrates, trimming the glycan and reducing disulfide bonds. The mannosidase component MNL1 uses its CTD to act on globular, misfolded proteins, generating an exposed alpha1,6-mannose residue that serves as a degradation signal. In a subsequent reaction, the PDI11 component of the complex uses GSH to reduce the disulfides of the demannosylated protein, gen- erating an unfolded polypeptide that can be retrotranslocated across the ER membrane (PubMed:16002399, PubMed:19124653, PubMed:21700223, PubMed:39930008)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6VQX3", "ec_number_list": "5.3.4.1", "go_molecular_function": "GO:0051082 unfolded protein binding;GO:0015035 protein-disulfide reductase activity;GO:0003756 protein disulfide isomerase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005788 endoplasmic reticulum lumen", "go_biological_process": "GO:0006457 protein folding;GO:0034976 response to endoplasmic reticulum stress;GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response;GO:1904382 mannose trimming involved in glycoprotein ERAD pathway;GO:0036508 protein alpha-1,2-demannosylation", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P17967-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P18238-1", "uniprot_id": "ADT3_YEAST", "mass": 33313.0, "length": 307, "protein_name": "ADP/ATP translocase 3", "gene_name": "AAC3", "organism": "Yeast", "refseq_name": "ADP/ATP carrier protein AAC3", "refseq_ac": "NP_009642", "gene_names_uniprotkb": "AAC3; YBR0753", "gene_names_refseq": "AAC3; ANC3", "protein_names_uniprotkb": "ADP/ATP translocase 3; ADP,ATP carrier protein 3; ANT 3; Adenine nucleotide translocator 3", "protein_names_refseq": "ADP/ATP carrier protein AAC3", "tax_id": 559292, "disease": "mitochondrial DNA depletion syndrome 12a (Disease Ontology:DOID:0080130); mitochondrial DNA depletion syndrome 12b (Disease Ontology:DOID:0080335); dilated cardiomyopathy 1H (Disease Ontology:DOID:0110429); autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 2 (Disease Ontology:DOID:0111517); Alzheimer's disease (Disease Ontology:DOID:10652); facioscapulohumeral muscular dystrophy (Disease Ontology:DOID:11727); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); chronic progressive external ophthalmoplegia (Disease Ontology:DOID:12558); alcoholic cardiomyopathy (Disease Ontology:DOID:12935); epilepsy (Disease Ontology:DOID:1826); mitochondrial myopathy (Disease Ontology:DOID:699); mitochondrial metabolism disease (Disease Ontology:DOID:700)", "pathway": " (sce:YBR085W); (R-SCE-1268020); (R-SCE-166187); (R-SCE-83936); (R-SCE-9837999)", "pathway_count": 5, "publication_count": 9, "publication_id_list": "12893834;14562106;20152151;2165073;23744064;24374639;24474793;33491328;7813418", "class_list": "", "function": "ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell (PubMed:2165073). Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane (By similarity)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 12, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQ85", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0005471 ATP:ADP antiporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005757 mitochondrial permeability transition pore complex", "go_biological_process": "GO:0055085 transmembrane transport;GO:0046902 regulation of mitochondrial membrane permeability;GO:0015886 heme transport;GO:0009061 anaerobic respiration;GO:0140021 mitochondrial ADP transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P18238-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P18409-1", "uniprot_id": "MDM10_YEAST", "mass": 56237.0, "length": 493, "protein_name": "Mitochondrial distribution and morphology protein 10", "gene_name": "MDM10", "organism": "Yeast", "refseq_name": "Mdm10p", "refseq_ac": "NP_009392", "gene_names_uniprotkb": "MDM10; FUN37", "gene_names_refseq": "FUN37; MDM10", "protein_names_uniprotkb": "Mitochondrial distribution and morphology protein 10; Mitochondrial inheritance component MDM10", "protein_names_refseq": "Mdm10p", "tax_id": 559292, "disease": "", "pathway": " (sce:YAL010C)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "12454062;12891361;13679517;14562095;14562106;14685243;15239954;16407407;16760475;17410204;19556461;2253888;24374639;7731988;7941740;8089171;8458570;9628893", "class_list": "", "function": "Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria., [UniProtKB, PubMed, PubMed, HAMAP, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VPK8", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0001401 SAM complex;GO:0005741 mitochondrial outer membrane;GO:0032865 ERMES complex", "go_biological_process": "GO:0045040 protein insertion into mitochondrial outer membrane;GO:0007031 peroxisome organization;GO:0015914 phospholipid transport;GO:0055091 phospholipid homeostasis;GO:0007005 mitochondrion organization", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P18409-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P18410-1", "uniprot_id": "SPO7_YEAST", "mass": 30114.0, "length": 259, "protein_name": "Sporulation-specific protein SPO7", "gene_name": "SPO7", "organism": "Yeast", "refseq_name": "Nem1-Spo7 phosphatase regulatory subunit SPO7", "refseq_ac": "NP_009393", "gene_names_uniprotkb": "SPO7", "gene_names_refseq": "SPO7", "protein_names_uniprotkb": "Sporulation-specific protein SPO7", "protein_names_refseq": "Nem1-Spo7 phosphatase regulatory subunit SPO7", "tax_id": 559292, "disease": "", "pathway": " (sce:YAL009W)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "14562106;15889145;16847258;17322287;2253888;23749301;24374639;29305265;30201607;31501244;33481703;33491328;7731988;7941740;9822591", "class_list": "", "function": "Regulatory component of the NEM1-SPO7 complex which acts as a phosphatase and dephosphorylates the phosphatidic acid phosphohydrolase PAH1 (PubMed:15889145). Essential for the formation of a spherical nucleus and meiotic division (PubMed:9822591). The NEM1-SPOo7 protein phosphatase is required for efficient mitophagy under prolonged respiration, as well as for reticulophagy and pexophagy (PubMed:29305265)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VPK9", "ec_number_list": "", "go_molecular_function": "GO:0019888 protein phosphatase regulator activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0031965 nuclear membrane;GO:0005789 endoplasmic reticulum membrane;GO:0071595 Nem1-Spo7 phosphatase complex", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0006998 nuclear envelope organization;GO:0061709 reticulophagy;GO:0071072 negative regulation of phospholipid biosynthetic process;GO:0071071 regulation of phospholipid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P18410-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P18412-1", "uniprot_id": "TEC1_YEAST", "mass": 55157.0, "length": 486, "protein_name": "Ty transcription activator TEC1", "gene_name": "TEC1", "organism": "Yeast", "refseq_name": "Tec1p", "refseq_ac": "NP_009639", "gene_names_uniprotkb": "TEC1; ROC1; YBR0750", "gene_names_refseq": "ROC1; TEC1", "protein_names_uniprotkb": "Ty transcription activator TEC1", "protein_names_refseq": "Tec1p", "tax_id": 559292, "disease": "Sveinsson chorioretinal atrophy (Disease Ontology:DOID:0111228)", "pathway": " (sce:YBR083W)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "14562106;15558284;15620356;15620357;17287358;17563356;19897738;2070413;21177495;2192259;22814378;23749301;24374639;32597660;33481703;33491328;7813418", "class_list": "", "function": "TEC1 is involved in the activation of TY1 and TY1-mediated gene expression. It is not involved in mating or sporulation processes., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQ82", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005667 transcription regulator complex;GO:1990527 Tec1p-Ste12p-Dig1p complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P18412-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P18480-1", "uniprot_id": "SNF5_YEAST", "mass": 102543.0, "length": 905, "protein_name": "SWI/SNF chromatin-remodeling complex subunit SNF5", "gene_name": "SNF5", "organism": "Yeast", "refseq_name": "Snf5p", "refseq_ac": "NP_009848", "gene_names_uniprotkb": "SNF5; SWI10; TYE4; YBR2036", "gene_names_refseq": "HAF4; SNF5; SWI10; TYE4", "protein_names_uniprotkb": "SWI/SNF chromatin-remodeling complex subunit SNF5; SWI/SNF complex subunit SNF5; Transcription factor TYE4; Transcription regulatory protein SNF5", "protein_names_refseq": "Snf5p", "tax_id": 559292, "disease": "colorectal adenocarcinoma (Disease Ontology:DOID:0050861); Coffin-Siris syndrome 3 (Disease Ontology:DOID:0070045); schwannomatosis 1 (Disease Ontology:DOID:0070480); rhabdoid tumor predisposition syndrome 1 (Disease Ontology:DOID:0070618); sinonasal undifferentiated carcinoma (Disease Ontology:DOID:0080799); vestibular schwannomatosis (Disease Ontology:DOID:0111252); atypical teratoid rhabdoid tumor (Disease Ontology:DOID:2129); schwannomatosis (Disease Ontology:DOID:3204); meningioma (Disease Ontology:DOID:3565); rhabdoid cancer (Disease Ontology:DOID:3672); clear cell renal cell carcinoma (Disease Ontology:DOID:4467); synovial sarcoma (Disease Ontology:DOID:5485); epithelioid sarcoma (Disease Ontology:DOID:6193); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (sce:YBR289W)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "12524530;14562095;14562106;17563356;18407956;19779198;19795423;19823750;22031224;2233708;23749301;24374639;32597660;33229814;33481703;33491328;7813418;8091861", "class_list": "", "function": "Involved in transcriptional activation. Component of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 4, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 4, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 4, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 14, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6VQT4", "ec_number_list": "", "go_molecular_function": "GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0016514 SWI/SNF complex;GO:0000785 chromatin;GO:0000228 nuclear chromosome", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0000724 double-strand break repair via homologous recombination", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P18480-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P18494-1", "uniprot_id": "GLN3_YEAST", "mass": 79383.0, "length": 730, "protein_name": "Nitrogen regulatory protein GLN3", "gene_name": "GLN3", "organism": "Yeast", "refseq_name": "nitrogen-responsive transcriptional regulator GLN3", "refseq_ac": "NP_010958", "gene_names_uniprotkb": "GLN3", "gene_names_refseq": "GLN3", "protein_names_uniprotkb": "Nitrogen regulatory protein GLN3", "protein_names_refseq": "nitrogen-responsive transcriptional regulator GLN3", "tax_id": 559292, "disease": "", "pathway": " (sce:YER040W); (R-SCE-9018519)", "pathway_count": 2, "publication_count": 22, "publication_id_list": "14562106;15665377;1682800;17330950;17467953;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22218487;23749301;24374639;32597660;33229814;33481703;33491328;9169868", "class_list": "", "function": "Positive nitrogen regulatory protein. Required for the activation of transcription of a number of genes (including the allantoin pathway genes) in response to the replacement of glutamine by glutamate as source of nitrogen. Binds the nitrogen upstream activation sequence of GLN1, the gene encoding glutamine synthetase. URE2 may catalytically inactivate GLN3 in response to an increase in the intracellular concentration of glutamine., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 11, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 11, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 11, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 52, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 10, "binding_glycan_count": 0, "secondary_ac_list": "D3DLU0", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0042128 nitrate assimilation", "synthesized_glycan_count": 0, "hit_score": 3.5, "record_id": "P18494-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P18562-1", "uniprot_id": "UPP_YEAST", "mass": 24594.0, "length": 216, "protein_name": "Uracil phosphoribosyltransferase", "gene_name": "FUR1", "organism": "Yeast", "refseq_name": "uracil phosphoribosyltransferase", "refseq_ac": "NP_011996", "gene_names_uniprotkb": "FUR1", "gene_names_refseq": "FUR1", "protein_names_uniprotkb": "Uracil phosphoribosyltransferase; 2.4.2.9; UMP pyrophosphorylase; UPRTase", "protein_names_refseq": "uracil phosphoribosyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR128W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "12748633;17287358;17322287;1913872;2189783;24374639;33481703;7929558;8091229", "class_list": "", "function": "Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate in the pyrimidine salvage pathway., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DL77", "ec_number_list": "2.4.2.9", "go_molecular_function": "GO:0005525 GTP binding;GO:0004845 uracil phosphoribosyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0008655 pyrimidine-containing compound salvage;GO:0044206 UMP salvage", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P18562-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P18759-1", "uniprot_id": "SEC18_YEAST", "mass": 84056.0, "length": 758, "protein_name": "Vesicular-fusion protein SEC18", "gene_name": "SEC18", "organism": "Yeast", "refseq_name": "AAA family ATPase SEC18", "refseq_ac": "NP_009636", "gene_names_uniprotkb": "SEC18; YBR0736", "gene_names_refseq": "ANU4; SEC18", "protein_names_uniprotkb": "Vesicular-fusion protein SEC18", "protein_names_refseq": "AAA family ATPase SEC18", "tax_id": 559292, "disease": "oculocutaneous albinism (Disease Ontology:DOID:0050632); autism spectrum disorder (Disease Ontology:DOID:0060041); developmental and epileptic encephalopathy 96 (Disease Ontology:DOID:0070377); Parkinson's disease (Disease Ontology:DOID:14330); epilepsy (Disease Ontology:DOID:1826); temporal lobe epilepsy (Disease Ontology:DOID:3328); cocaine dependence (Disease Ontology:DOID:9975)", "pathway": " (sce:YBR080C); (R-SCE-204005); (R-SCE-6807878); (R-SCE-6811434); (R-SCE-6811438); (R-SCE-6811440)", "pathway_count": 6, "publication_count": 19, "publication_id_list": "10611286;14562106;17287358;17563356;18407956;19779198;19795423;19823750;21126336;21177495;23749301;24374639;30516470;3054509;32597660;33481703;33491328;7813418;7985423", "class_list": "", "function": "Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQ79;Q07067", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0000149 SNARE binding;GO:0070300 phosphatidic acid binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0005795 Golgi stack;GO:0043332 mating projection tip", "go_biological_process": "GO:0035494 SNARE complex disassembly;GO:0042144 vacuole fusion, non-autophagic;GO:0000045 autophagosome assembly;GO:0016236 macroautophagy;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P18759-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P18852-1", "uniprot_id": "GBG_YEAST", "mass": 12625.0, "length": 110, "protein_name": "Guanine nucleotide-binding protein subunit gamma", "gene_name": "STE18", "organism": "Yeast", "refseq_name": "Ste18p", "refseq_ac": "NP_012619", "gene_names_uniprotkb": "STE18; J1866", "gene_names_refseq": "STE18", "protein_names_uniprotkb": "Guanine nucleotide-binding protein subunit gamma", "protein_names_refseq": "Ste18p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR086W)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "10523659;10712512;10749875;14562106;17322287;19795423;19823750;22814378;24374639;2536595;29719261;32597660;33491328;34158397;7982577;8641269;8840504", "class_list": "", "function": "Implicated in the pheromone A- and alpha-factor response pathway. The beta and gamma chains of the putative yeast mating response pathway G protein play a positive role in initiation of the mating response., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWQ5", "ec_number_list": "", "go_molecular_function": "GO:0031681 G-protein beta-subunit binding", "go_cellular_component": "GO:0031680 G-protein beta/gamma-subunit complex;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0071944 cell periphery", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0010969 regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion;GO:0000750 pheromone-dependent signal transduction involved in conjugation with cellular fusion", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P18852-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P18888-1", "uniprot_id": "SNF6_YEAST", "mass": 37607.0, "length": 332, "protein_name": "Transcription regulatory protein SNF6", "gene_name": "SNF6", "organism": "Yeast", "refseq_name": "Snf6p", "refseq_ac": "NP_011838", "gene_names_uniprotkb": "SNF6", "gene_names_refseq": "SNF6", "protein_names_uniprotkb": "Transcription regulatory protein SNF6; SWI/SNF complex component SNF6", "protein_names_refseq": "Snf6p", "tax_id": 559292, "disease": "", "pathway": " (sce:YHL025W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "12524530;14562106;18407956;2188093;22814378;23749301;24374639;33481703;33491328;8091229", "class_list": "", "function": "Involved in transcriptional activation. Component of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DKU3", "ec_number_list": "", "go_molecular_function": "GO:0000182 rDNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0016514 SWI/SNF complex;GO:0000785 chromatin", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045943 positive regulation of transcription by RNA polymerase I", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P18888-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P18898-1", "uniprot_id": "PGTB1_YEAST", "mass": 42690.0, "length": 376, "protein_name": "Geranylgeranyl transferase type-1 subunit beta", "gene_name": "CDC43", "organism": "Yeast", "refseq_name": "protein geranylgeranyltransferase type I subunit CDC43", "refseq_ac": "NP_011360", "gene_names_uniprotkb": "CDC43; CAL1; G1864", "gene_names_refseq": "CAL1; CDC43", "protein_names_uniprotkb": "Geranylgeranyl transferase type-1 subunit beta; 2.5.1.59; Cell division cycle protein 43; GGTase-I-beta; Geranylgeranyl transferase type I subunit beta; PGGTase I beta; RAS proteins geranylgeranyltransferase subunit beta; Type I protein geranyl-geranyltransferase subunit beta", "protein_names_refseq": "protein geranylgeranyltransferase type I subunit CDC43", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL155W)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "10491163;1400380;14562095;14562106;1918005;2013407;2034682;2061313;2199333;24374639;6369073;7639519;8494894;8585324;8804398;9109664;9169869", "class_list": "", "function": "Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl diphosphate to proteins having the C-terminal sequence Cys-Ile-Ile-Leu or Cys-Val-Leu-Leu. Acts, among other substrates, on Rho1 and Rho2 and CDC42 proteins. Participates in a RAS-like C-terminal modification of proteins involved in nuclear division and bud growth. It is involved in bud positioning and cell polarity (PubMed:1400380, PubMed:2034682). The beta subunit is responsible for isoprenoid and peptide-binding (PubMed:10491163, PubMed:9109664)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 9, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTZ6", "ec_number_list": "2.5.1.59;2.5.1.60;2.5.1.58", "go_molecular_function": "GO:0004662 CAAX-protein geranylgeranyltransferase activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005953 CAAX-protein geranylgeranyltransferase complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0018344 protein geranylgeranylation", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P18898-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P18899-1", "uniprot_id": "DDR48_YEAST", "mass": 46233.0, "length": 430, "protein_name": "Stress protein DDR48", "gene_name": "DDR48", "organism": "Yeast", "refseq_name": "DNA damage-responsive protein 48", "refseq_ac": "NP_013897", "gene_names_uniprotkb": "DDR48; FSP; YM8010.03", "gene_names_refseq": "DDR48", "protein_names_uniprotkb": "Stress protein DDR48; DDRP 48; DNA damage-responsive protein 48; Flocculent-specific protein; YP 75", "protein_names_refseq": "DNA damage-responsive protein 48", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR173W)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "17563356;18407956;19779198;19795423;19823750;2111448;21126336;2114092;21177495;23125229;23749301;24374639;3023840;30516470;33481703;33491328;8089083;8444852;9169872", "class_list": "", "function": "DNA damage-responsive protein that may be required for maintaining the rate of spontaneous mutagenesis. Shows low ATP and GTP hydrolysis activity. Dispensable for acquisition of thermotolerance and does not play a significant role in recovery or protection of cells from acute heat shock., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 66, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZZ5", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006281 DNA repair", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P18899-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P18961-1", "uniprot_id": "YPK2_YEAST", "mass": 76664.0, "length": 677, "protein_name": "Serine/threonine-protein kinase YPK2/YKR2", "gene_name": "YPK2", "organism": "Yeast", "refseq_name": "putative protein kinase YPK2", "refseq_ac": "NP_013822", "gene_names_uniprotkb": "YPK2; YKR2; YM9718.03C", "gene_names_refseq": "YKR2; YPK2", "protein_names_uniprotkb": "Serine/threonine-protein kinase YPK2/YKR2; 2.7.11.1", "protein_names_refseq": "putative protein kinase YPK2", "tax_id": 559292, "disease": "hypertension (Disease Ontology:DOID:10763); transient cerebral ischemia (Disease Ontology:DOID:224); granulosa cell tumor (Disease Ontology:DOID:2999); serous cystadenocarcinoma (Disease Ontology:DOID:3114); mucinous cystadenocarcinoma (Disease Ontology:DOID:3603)", "pathway": " (sce:YMR104C)", "pathway_count": 1, "publication_count": 24, "publication_id_list": "10074427;12221112;14562095;14562106;15840588;16055732;17330950;17563356;18407956;19779198;19795423;19823750;20489023;21177495;23749301;24374639;2663649;30516470;32597660;33481703;33491328;39490931;8437590;9169872", "class_list": "", "function": "Plays an essential role in the proliferation of yeast cells (PubMed:8437590). Involved in a signaling pathway, required for optimal cell wall integrity, that acts in parallel with the PKC1-SLT2-dependent pathway (PubMed:12221112). A substrate of TOR complex 2 (TORC2) and required for TORC2 to regulate spatial aspects of cell growth (PubMed:16055732). Phosphorylation of residue Thr-501 is indispensable for function. May act as a downstream kinase in the sphingolipid-mediated signaling pathway (PubMed:39490931)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 22, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZS6", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "GO:0006665 sphingolipid metabolic process;GO:0008360 regulation of cell shape;GO:0060237 regulation of fungal-type cell wall organization;GO:0070941 eisosome assembly;GO:0071555 cell wall organization", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "P18961-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P19145-1", "uniprot_id": "GAP1_YEAST", "mass": 65656.0, "length": 602, "protein_name": "General amino-acid permease GAP1", "gene_name": "GAP1", "organism": "Yeast", "refseq_name": "amino acid permease GAP1", "refseq_ac": "NP_012965", "gene_names_uniprotkb": "GAP1", "gene_names_refseq": "GAP1", "protein_names_uniprotkb": "General amino-acid permease GAP1", "protein_names_refseq": "amino acid permease GAP1", "tax_id": 559292, "disease": "retinitis pigmentosa 68 (Disease Ontology:DOID:0110374)", "pathway": " (sce:YKR039W)", "pathway_count": 1, "publication_count": 27, "publication_id_list": "10194416;10373490;10467005;10953083;11352928;11500494;12417748;12499351;12872131;14523026;14557538;14968425;15039776;15707981;16847258;17322287;21471002;2194797;22844449;24374639;33481703;33491328;5474888;7798155;8196765;8636059;9614172", "class_list": "", "function": "General amino-acid permease involved in the uptake of all the naturally occurring L-amino-acids, related compounds such as ornithine and citrulline, some D-amino acids, toxic amino acid analogs such as azetidine-2-carboxylate, and the polyamines putrescine and spermidine (PubMed:10373490, PubMed:10467005, PubMed:10953083, PubMed:14968425, PubMed:15707981, PubMed:5474888). Senses its transport substrates to set an appropriate level of transporter activity at the cell surface (PubMed:21471002). Required for FLO11 expression and invasive growth (PubMed:22844449)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VXA2", "ec_number_list": "", "go_molecular_function": "GO:0015193 L-proline transmembrane transporter activity;GO:0015171 amino acid transmembrane transporter activity;GO:0001761 beta-alanine transmembrane transporter activity;GO:0015192 L-phenylalanine transmembrane transporter activity;GO:0015203 polyamine transmembrane transporter activity", "go_cellular_component": "GO:0005768 endosome;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030134 COPII-coated ER to Golgi transport vesicle", "go_biological_process": "GO:0006865 amino acid transport;GO:0003333 amino acid transmembrane transport;GO:0015846 polyamine transport", "synthesized_glycan_count": 0, "hit_score": 2.8, "record_id": "P19145-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P19211-1", "uniprot_id": "IF5A2_YEAST", "mass": 17131.0, "length": 157, "protein_name": "Eukaryotic translation initiation factor 5A-2", "gene_name": "ANB1", "organism": "Yeast", "refseq_name": "translation elongation factor eIF-5A", "refseq_ac": "NP_012581", "gene_names_uniprotkb": "ANB1; HYP1; J1651; TIF51B", "gene_names_refseq": "ANB1; HYP1; TIF51B", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 5A-2; Anaerobically induced protein 1; Hypusine-containing protein HP1; eIF-4D; eIF-5A-2", "protein_names_refseq": "translation elongation factor eIF-5A", "tax_id": 559292, "disease": "pulmonary hypertension (Disease Ontology:DOID:6432); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (sce:YJR047C); (R-SCE-204626)", "pathway_count": 2, "publication_count": 23, "publication_id_list": "14562106;17322287;18407956;1903841;19338753;19424157;19779198;2187871;2233724;24374639;2656688;2852136;3062365;3119589;32597660;33491328;33502312;3540607;641056;7668047;8307948;8314769;8641269", "class_list": "", "function": "Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts (PubMed:19338753, PubMed:19424157, PubMed:641056, PubMed:8307948). Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome (By similarity). Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step (By similarity). Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity (By similarity)., [UniProtKB, UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWL8", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0003746 translation elongation factor activity;GO:0043022 ribosome binding", "go_cellular_component": "GO:0022626 cytosolic ribosome", "go_biological_process": "GO:0006452 translational frameshifting;GO:0045901 positive regulation of translational elongation;GO:0045905 positive regulation of translational termination;GO:0006414 translational elongation", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P19211-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P19263-1", "uniprot_id": "MED14_YEAST", "mass": 123358.0, "length": 1082, "protein_name": "Mediator of RNA polymerase II transcription subunit 14", "gene_name": "RGR1", "organism": "Yeast", "refseq_name": "Rgr1p", "refseq_ac": "NP_013172", "gene_names_uniprotkb": "RGR1; MED14", "gene_names_refseq": "MED14; RGR1", "protein_names_uniprotkb": "Mediator of RNA polymerase II transcription subunit 14; Glucose repression regulatory protein 1; Mediator complex subunit 14", "protein_names_refseq": "Rgr1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR071C)", "pathway_count": 1, "publication_count": 27, "publication_id_list": "11383511;12191485;14562095;14562106;14623974;14749387;15175151;15477388;15665377;16002404;16076843;16263706;16630888;17192271;17322287;17330950;18407956;19779198;2196447;22218487;24374639;32597660;33481703;33491328;7479899;7635307;9169871", "class_list": "", "function": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. The Mediator complex unfolds to an extended conformation and partially surrounds RNA polymerase II, specifically interacting with the unphosphorylated form of the C-terminal domain (CTD) of RNA polymerase II. The Mediator complex dissociates from the RNA polymerase II holoenzyme and stays at the promoter when transcriptional elongation begins., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VY72;Q07999", "ec_number_list": "", "go_molecular_function": "GO:0001093 TFIIB-class transcription factor binding;GO:0003712 transcription coregulator activity;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016592 mediator complex;GO:0070847 core mediator complex", "go_biological_process": "GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0032968 positive regulation of transcription elongation by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 2.8, "record_id": "P19263-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P19414-1", "uniprot_id": "ACON_YEAST", "mass": 85368.0, "length": 778, "protein_name": "Aconitate hydratase, mitochondrial", "gene_name": "ACO1", "organism": "Yeast", "refseq_name": "aconitate hydratase ACO1", "refseq_ac": "NP_013407", "gene_names_uniprotkb": "ACO1; GLU1; L8003.22", "gene_names_refseq": "ACO1; GLU1", "protein_names_uniprotkb": "Aconitate hydratase, mitochondrial; 4.2.1.3; Aconitase; Citrate hydro-lyase", "protein_names_refseq": "aconitate hydratase ACO1", "tax_id": 559292, "disease": "infantile cerebellar-retinal degeneration (Disease Ontology:DOID:0050883); optic atrophy 9 (Disease Ontology:DOID:0111442); neurodegenerative disease (Disease Ontology:DOID:1289); optic nerve disease (Disease Ontology:DOID:1891); central nervous system disease (Disease Ontology:DOID:331)", "pathway": " (sce:YLR304C); (R-SCE-71403); (R-SCE-9837999); (R-SCE-9854311)", "pathway_count": 4, "publication_count": 22, "publication_id_list": "10224250;14562106;15692048;15975908;17330950;17698960;17761666;18359281;18407956;18577574;1972545;19779198;21440554;23106124;23749301;24066190;24374639;27738674;32597660;33481703;33491328;9169871", "class_list": "", "function": "Catalyzes the isomerization of citrate to isocitrate via cis-aconitate, a step in the citric acid cycle. Can also provide minor contributions to the reversible dehydration of (R)-homocitrate to cis-homoaconitate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. Also plays an essential role in mtDNA maintenance. May directly protect mtDNA from accumulation of point mutations and ssDNA breaks as a component of mitochondrial nucleoids, or by preventing accumulation of iron citrate thereby alleviating its detrimental effects in mitochondria., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 18, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VYU7", "ec_number_list": "1.1.2.3;3.5.3.1;7.1.2.2;2.3.3.1;7.1.1.8;4.2.1.2;3.6.4.10;4.98.1.1;4.2.1.3;1.2.4.2;1.1.1.37;1.1.1.41;1.2.4.1;3.6.1.-;3.4.21.53;2.3.1.41;1.2.1.4;1.2.1.5;6.1.1.5;2.3.3.10;1.16.3.1", "go_molecular_function": "GO:0003729 mRNA binding;GO:0003994 aconitate hydratase activity;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0003690 double-stranded DNA binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005758 mitochondrial intermembrane space;GO:0005759 mitochondrial matrix;GO:0005829 cytosol;GO:0042645 mitochondrial nucleoid", "go_biological_process": "GO:0006099 tricarboxylic acid cycle", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "P19414-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P19454-1", "uniprot_id": "CSK22_YEAST", "mass": 39404.0, "length": 339, "protein_name": "Casein kinase II subunit alpha'", "gene_name": "CKA2", "organism": "Yeast", "refseq_name": "casein kinase 2 catalytic subunit CKA2", "refseq_ac": "NP_014704", "gene_names_uniprotkb": "CKA2; YOR29-12", "gene_names_refseq": "CKA2; YOR29-12", "protein_names_uniprotkb": "Casein kinase II subunit alpha'; 2.7.11.1; CK II", "protein_names_refseq": "casein kinase 2 catalytic subunit CKA2", "tax_id": 559292, "disease": "male infertility (Disease Ontology:DOID:12336); breast cancer (Disease Ontology:DOID:1612); myocardial infarction (Disease Ontology:DOID:5844)", "pathway": " (sce:YOR061W); (R-SCE-2514853); (R-SCE-6804756); (R-SCE-8934903); (R-SCE-8948751)", "pathway_count": 5, "publication_count": 11, "publication_id_list": "12242279;14562106;17322287;18086883;2196445;22156209;22814378;24374639;3468112;9133743;9169874", "class_list": "", "function": "Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine (By similarity). Phosphorylates YTA7 during S-phase to promote transcription of histones (PubMed:22156209)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2C4", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.1.1.-;2.7.11.17;2.7.11.23;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.6.4.13;3.6.-.-;3.1.3.67;2.1.1.260;3.6.5.-;3.6.1.-", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005956 protein kinase CK2 complex;GO:0032040 small-subunit processome", "go_biological_process": "GO:0006974 DNA damage response;GO:0051726 regulation of cell cycle;GO:0006359 regulation of transcription by RNA polymerase III;GO:0000028 ribosomal small subunit assembly;GO:0006356 regulation of transcription by RNA polymerase I", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P19454-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P19524-1", "uniprot_id": "MYO2_YEAST", "mass": 180680.0, "length": 1574, "protein_name": "Myosin-2", "gene_name": "MYO2", "organism": "Yeast", "refseq_name": "myosin 2", "refseq_ac": "NP_014971", "gene_names_uniprotkb": "MYO2; CDC66; O6167", "gene_names_refseq": "CDC66; MYO2", "protein_names_uniprotkb": "Myosin-2; Cell division control protein 66; Class V unconventional myosin MYO2; Myosin V MYO2; Type V myosin heavy chain MYO2", "protein_names_refseq": "myosin 2", "tax_id": 559292, "disease": "microvillus inclusion disease (Disease Ontology:DOID:0060775); Griscelli syndrome type 1 (Disease Ontology:DOID:0060832); progressive familial intrahepatic cholestasis (Disease Ontology:DOID:0070221)", "pathway": " (sce:YOR326W); (R-SCE-190873); (R-SCE-9013419); (R-SCE-9013420); (R-SCE-9013425)", "pathway_count": 5, "publication_count": 44, "publication_id_list": "10207081;10679024;10931864;10984058;11285273;11381095;11733545;11781333;12351846;12391144;12456647;12554638;12642614;12725728;12743102;14562106;15201867;15964280;16467380;17330950;17563356;18407956;19779198;19795423;19823750;2016335;20702584;21126336;21177495;21248204;22218487;22814378;23749301;24374639;32597660;33481703;33491328;8188749;8294515;8896263;8896266;9169874;9700160;9843969", "class_list": "", "function": "Myosin heavy chain that is required for the cell cycle-regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables. Essential for the delivery of secretory vesicles to sites of active growth during bud emergence and cytokinesis. Required for segregation and inheritance of peroxisomes, late Golgi compartments, mitochondria and the vacuole to the daughter cell during cell division. Also required for correct alignment of the spindle during mitosis., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 19, "reported_mutagensis": 25, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W323", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0031267 small GTPase binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0015629 actin cytoskeleton;GO:0016020 membrane;GO:0030133 transport vesicle;GO:0031982 vesicle", "go_biological_process": "GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0015031 protein transport;GO:0006898 receptor-mediated endocytosis;GO:0016192 vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 4.5, "record_id": "P19524-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P19541-1", "uniprot_id": "RDS2_YEAST", "mass": 50082.0, "length": 446, "protein_name": "Regulator of drug sensitivity 2", "gene_name": "RDS2", "organism": "Yeast", "refseq_name": "gluconeogenesis transcription factor RDS2", "refseq_ac": "NP_015192", "gene_names_uniprotkb": "RDS2; LPI12C", "gene_names_refseq": "RDS2", "protein_names_uniprotkb": "Regulator of drug sensitivity 2", "protein_names_refseq": "gluconeogenesis transcription factor RDS2", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL133C)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "11943786;1304897;14562095;14562106;16652171;16785442;17322287;17875938;18407956;18683633;20702584;21126336;21177495;2167832;23749301;24374639;32597660;33481703;33491328;9169875", "class_list": "", "function": "Transcription factor which regulates the expression of genes for gluconeogenesis, the TCA cycle, and glucose metabolism. Involved in the cell wall remodeling process and drug resistance., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3N4", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0043565 sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0071466 cellular response to xenobiotic stimulus;GO:0045722 positive regulation of gluconeogenesis", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P19541-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P19657-1", "uniprot_id": "PMA2_YEAST", "mass": 102172.0, "length": 947, "protein_name": "Plasma membrane ATPase 2", "gene_name": "PMA2", "organism": "Yeast", "refseq_name": "H(+)-exporting P2-type ATPase PMA2", "refseq_ac": "NP_015289", "gene_names_uniprotkb": "PMA2", "gene_names_refseq": "PMA2", "protein_names_uniprotkb": "Plasma membrane ATPase 2; 7.1.2.1; Proton pump 2", "protein_names_refseq": "H(+)-exporting P2-type ATPase PMA2", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL036W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "11875433;16847258;17287358;24374639;2904437;9169875", "class_list": "", "function": "The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3X8", "ec_number_list": "7.1.2.1", "go_molecular_function": "GO:0008553 P-type proton-exporting transporter activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005886 plasma membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0051453 regulation of intracellular pH;GO:1902600 proton transmembrane transport;GO:0120029 proton export across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P19657-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P19658-1", "uniprot_id": "EXO70_YEAST", "mass": 71294.0, "length": 623, "protein_name": "Exocyst complex component EXO70", "gene_name": "EXO70", "organism": "Yeast", "refseq_name": "GTP-Rho binding exocyst subunit EXO70", "refseq_ac": "NP_012450", "gene_names_uniprotkb": "EXO70; J0932", "gene_names_refseq": "EXO70", "protein_names_uniprotkb": "Exocyst complex component EXO70; Exocyst complex protein of 70 kDa", "protein_names_refseq": "GTP-Rho binding exocyst subunit EXO70", "tax_id": 559292, "disease": "microcephaly (Disease Ontology:DOID:10907)", "pathway": " (sce:YJL085W); (R-SCE-264876)", "pathway_count": 2, "publication_count": 14, "publication_id_list": "10207081;14562095;14562106;15583030;15583031;15788396;16249794;17322287;24374639;3277966;3317276;7483841;8641269;8978675", "class_list": "", "function": "Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Plays a role in the assembly of the exocyst., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VW98;E9P961", "ec_number_list": "", "go_molecular_function": "GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030133 transport vesicle;GO:0000145 exocyst;GO:0000131 incipient cellular bud site", "go_biological_process": "GO:0051601 exocyst localization;GO:0015031 protein transport;GO:0007266 Rho protein signal transduction;GO:0006887 exocytosis;GO:0006893 Golgi to plasma membrane transport", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P19658-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P19807-1", "uniprot_id": "HNM1_YEAST", "mass": 62056.0, "length": 563, "protein_name": "Choline transporter", "gene_name": "HNM1", "organism": "Yeast", "refseq_name": "Hnm1p", "refseq_ac": "NP_011438", "gene_names_uniprotkb": "HNM1; CTR1; CTR", "gene_names_refseq": "CTR1; HNM1", "protein_names_uniprotkb": "Choline transporter", "protein_names_refseq": "Hnm1p", "tax_id": 559292, "disease": "proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome (Disease Ontology:DOID:0111666)", "pathway": " (sce:YGL077C)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "16847258;17322287;19684113;19779198;19795423;19823750;20702584;21177495;2203793;22218487;23749301;24374639;30516470;32597660;33481703;33491328;3514579;9169869;9290212", "class_list": "", "function": "Sole choline transporter in yeast (PubMed:3514579). Also transports ethanolamine (PubMed:3514579)., [UniProtKB, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "D6VU67", "ec_number_list": "", "go_molecular_function": "GO:0015220 choline transmembrane transporter activity;GO:0015185 gamma-aminobutyric acid transmembrane transporter activity;GO:1901235 (R)-carnitine transmembrane transporter activity;GO:0034228 ethanolamine transmembrane transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0031460 glycine betaine transport;GO:0015871 choline transport;GO:0015812 gamma-aminobutyric acid transport;GO:1900749 (R)-carnitine transport;GO:0034229 ethanolamine transport", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P19807-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P19880-1", "uniprot_id": "AP1_YEAST", "mass": 72533.0, "length": 650, "protein_name": "AP-1-like transcription factor YAP1", "gene_name": "YAP1", "organism": "Yeast", "refseq_name": "DNA-binding transcription factor YAP1", "refseq_ac": "NP_013707", "gene_names_uniprotkb": "YAP1; PAR1; PDR4; SNQ3; YM9571.12", "gene_names_refseq": "PAR1; PDR4; SNQ3; YAP1", "protein_names_uniprotkb": "AP-1-like transcription factor YAP1; Phenanthroline resistance protein PAR1; Pleiotropic drug resistance protein PDR4", "protein_names_refseq": "DNA-binding transcription factor YAP1", "tax_id": 559292, "disease": "", "pathway": " (sce:YML007W)", "pathway_count": 1, "publication_count": 49, "publication_id_list": "10347154;10844671;11013218;11102521;11274141;11509657;12006656;12437921;12582119;12743123;14556629;14556853;14562106;1525853;15318225;15665377;17287358;17330950;17563356;17707237;17720812;18407956;1878996;1889413;19448108;19779198;19795423;19823750;2060792;20702584;20971184;21126336;21177495;22218487;23749301;24374639;2542125;27821475;30516470;32597660;33481703;33491328;8182076;9065458;9130715;9169872;9372930;9469820;9857197", "class_list": "", "function": "Transcription activator involved in oxidative stress response and redox homeostasis. Regulates the transcription of genes encoding antioxidant enzymes and components of the cellular thiol-reducing pathways, including the thioredoxin system (TRX2, TRR1), the glutaredoxin system (GSH1, GLR1), superoxide dismutase (SOD1, SOD2), glutathione peroxidase (GPX2), and thiol-specific peroxidases (TSA1, AHP1). The induction of some of these genes requires the cooperative action of both, YAP1 and SKN7. Preferentially binds to promoters with the core binding site 5'-TTA[CG]TAA-3'. Activity of the transcription factor is controlled through oxidation of specific cysteine residues resulting in the alteration of its subcellular location. Oxidative stress (as well as carbon stress, but not increased temperature, acidic pH, or ionic stress) induces nuclear accumulation and as a result YAP1 transcriptional activity. Activation by hydrogen peroxide or thiol-reactive chemicals elicit distinct adaptive gene responses. Nuclear export is restored when disulfide bonds are reduced by thioredoxin (TRX2), whose expression is controlled by YAP1, providing a mechanism for negative autoregulation. When overexpressed, YAP1 confers pleiotropic drug-resistance and increases cellular tolerance to cadmium, iron chelators and zinc., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 35, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZG8;P22631;Q06840", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0003700 DNA-binding transcription factor activity;GO:0000976 transcription cis-regulatory region binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0090575 RNA polymerase II transcription regulator complex", "go_biological_process": "GO:0046685 response to arsenic-containing substance;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0046686 response to cadmium ion", "synthesized_glycan_count": 0, "hit_score": 5.0, "record_id": "P19880-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P20050-1", "uniprot_id": "HOP1_YEAST", "mass": 68876.0, "length": 605, "protein_name": "Meiosis-specific protein HOP1", "gene_name": "HOP1", "organism": "Yeast", "refseq_name": "Hop1p", "refseq_ac": "NP_012193", "gene_names_uniprotkb": "HOP1", "gene_names_refseq": "HOP1", "protein_names_uniprotkb": "Meiosis-specific protein HOP1", "protein_names_refseq": "Hop1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL072W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "18329363;2107981;23047948;24374639;24465650;26225562;28357333;29853474;30289413;33502312;8462842;9169870", "class_list": "", "function": "Probable constituent of the synaptonemal complex during meiosis. May interact with RED1., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 19, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVL2", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0000400 four-way junction DNA binding", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0005634 nucleus;GO:0000800 lateral element;GO:0000795 synaptonemal complex", "go_biological_process": "GO:0051598 meiotic recombination checkpoint signaling;GO:0007130 synaptonemal complex assembly;GO:0007129 homologous chromosome pairing at meiosis;GO:0007131 reciprocal meiotic recombination;GO:0035825 homologous recombination", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P20050-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P20052-1", "uniprot_id": "PHO80_YEAST", "mass": 33227.0, "length": 293, "protein_name": "PHO85 cyclin PHO80", "gene_name": "PHO80", "organism": "Yeast", "refseq_name": "Pho80p", "refseq_ac": "NP_014642", "gene_names_uniprotkb": "PHO80; AGS3; O2505; TUP7; UNB293; VAC5", "gene_names_refseq": "AGS3; PHO80; TUP7; VAC5", "protein_names_uniprotkb": "PHO85 cyclin PHO80; Aminoglycoside antibiotic sensitivity protein 3; Phosphate system cyclin PHO80", "protein_names_refseq": "Pho80p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL001W)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "15057567;16308562;16455487;19779198;2269431;24374639;3283704;3302947;3333302;33491328;7939631;7957107;8108735;8187772;8539622;8896276;9169874;9732266;9853758", "class_list": "", "function": "Cyclin partner of the cyclin-dependent kinase (CDK) PHO85. Negatively regulates the expression of phosphate-starvation-responsive genes under phosphate-rich conditions. The PHO80-PHO85 cyclin-CDK holoenzyme phosphorylates and inactivates the transcription factor PHO4, by preventing its association with the transcription factor PHO2 and the nuclear import receptor PSE1, and by promoting association with the nuclear export receptor MSN5, excluding PHO4 from the nucleus. PHO80-PHO85 phosphorylates and inactivates protein kinase RIM15 by retaining it in the cytoplasm, antagonizing RIM15-induced entry into stationary phase. PHO80-PHO85 also phosphorylates and inactivates the calcineurin-responsive transcription factor CRZ1, linking PHO85 to calcium signaling., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W266;Q06882;Q06883", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding;GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000307 cyclin-dependent protein kinase holoenzyme complex;GO:1990860 Pho85-Pho80 CDK-cyclin complex", "go_biological_process": "GO:0050849 negative regulation of calcium-mediated signaling;GO:0042144 vacuole fusion, non-autophagic;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0032880 regulation of protein localization;GO:0016242 negative regulation of macroautophagy", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P20052-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P20081-1", "uniprot_id": "FKBP_YEAST", "mass": 12158.0, "length": 114, "protein_name": "FK506-binding protein 1", "gene_name": "FPR1", "organism": "Yeast", "refseq_name": "peptidylprolyl isomerase FPR1", "refseq_ac": "NP_014264", "gene_names_uniprotkb": "FPR1; FKB1; N1213; N1845; RBP1", "gene_names_refseq": "FKB1; FPR1; RBP1", "protein_names_uniprotkb": "FK506-binding protein 1; 12-kDa cytosolic FK506-binding protein; 5.2.1.8; FKBP-12; FKBP; PPIase; Peptidyl-prolyl cis-trans isomerase; Rapamycin-binding protein", "protein_names_refseq": "peptidylprolyl isomerase FPR1", "tax_id": 559292, "disease": "Barth syndrome (Disease Ontology:DOID:0050476); cardiomyopathy (Disease Ontology:DOID:0050700); catecholaminergic polymorphic ventricular tachycardia (Disease Ontology:DOID:0060674); Parkinsonism (Disease Ontology:DOID:0080855); Graves' disease (Disease Ontology:DOID:12361); congestive heart failure (Disease Ontology:DOID:6000)", "pathway": " (sce:YNL135C); (R-SCE-166208); (R-SCE-2025928)", "pathway_count": 3, "publication_count": 23, "publication_id_list": "10049913;10998178;14562106;16823961;1701173;1704127;1705713;17322287;17563356;18407956;19779198;1996117;20305002;21177495;22814378;23749301;24374639;33481703;33491328;7681823;8619318;9169873;9315655", "class_list": "", "function": "PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (PubMed:1996117). Plays a role in feedback inhibition of the pathway synthesizing the aspartate family of amino acids by binding to aspartokinase (PubMed:9315655)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W147", "ec_number_list": "5.2.1.8", "go_molecular_function": "GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0005527 macrolide binding;GO:0044183 protein folding chaperone;GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0070651 nonfunctional rRNA decay;GO:0006457 protein folding;GO:0006325 chromatin organization;GO:0006366 transcription by RNA polymerase II;GO:1901710 regulation of homoserine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P20081-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P20095-1", "uniprot_id": "PRP2_YEAST", "mass": 99814.0, "length": 876, "protein_name": "Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2", "gene_name": "PRP2", "organism": "Yeast", "refseq_name": "DEAH-box RNA-dependent ATPase PRP2", "refseq_ac": "NP_014408", "gene_names_uniprotkb": "PRP2; N2048; RNA2", "gene_names_refseq": "PRP2; RNA2", "protein_names_uniprotkb": "Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2; 3.6.4.13; Pre-mRNA-processing protein 2", "protein_names_refseq": "DEAH-box RNA-dependent ATPase PRP2", "tax_id": 559292, "disease": "", "pathway": " (sce:YNR011C)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "14562095;14562106;14730020;1534753;15542821;17563356;21126336;2147058;2251118;22814378;24374639;33481703;33491328;3536958;7493316;7900425;8112301;8112302;8943336;9169873", "class_list": "", "function": "Involved in pre-mRNA splicing. Is required together with ATP and at least one other factor, for the first cleavage-ligation reaction. Functions as a molecular motor in the activation of the precatalytic spliceosome for the first transesterification reaction of pre-mRNA splicing by hydrolyzing ATP to cause the activation of the spliceosome without the occurrence of splicing. Capable of hydrolyzing nucleoside triphosphates in the presence of single-stranded RNAs such as poly(U)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 15, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1I6", "ec_number_list": "3.6.4.13;5.6.2.3;3.6.4.10;3.6.-.-;5.6.2.4;3.6.4.-;5.6.1.4;3.6.4.12;3.6.4.6;5.6.2.5;3.6.1.-;2.3.2.27;3.1.-.-;3.4.24.-;3.6.5.-;2.7.4.3;2.7.11.1;7.2.2.-", "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0004386 helicase activity;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:0071006 U2-type catalytic step 1 spliceosome", "go_biological_process": "GO:0000349 generation of catalytic spliceosome for first transesterification step;GO:0034247 snoRNA splicing", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P20095-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P20107-1", "uniprot_id": "ZRC1_YEAST", "mass": 48345.0, "length": 442, "protein_name": "Vacuolar zinc transporter ZRC1", "gene_name": "ZRC1", "organism": "Yeast", "refseq_name": "Zn(2+) transporter ZRC1", "refseq_ac": "NP_013970", "gene_names_uniprotkb": "ZRC1; YM9408.05C", "gene_names_refseq": "OSR1; ZRC1", "protein_names_uniprotkb": "Vacuolar zinc transporter ZRC1; Zinc resistance conferring protein 1; Zinc/cadmium resistance protein ZRC1", "protein_names_refseq": "Zn(2+) transporter ZRC1", "tax_id": 559292, "disease": "hypermanganesemia with dystonia 1 (Disease Ontology:DOID:0080536)", "pathway": " (sce:YMR243C); (R-SCE-425410); (R-SCE-435368)", "pathway_count": 3, "publication_count": 23, "publication_id_list": "10856230;11263974;12161436;12556516;14562106;16169922;16847258;17322287;17330950;17563356;18930916;19684113;19779198;22106047;22814378;23749301;24374639;2693940;32597660;33481703;33491328;9169872;9712830", "class_list": "", "function": "Vacuolar transporter that regulates zinc homeostasis by mediating zinc transport and storage into the vacuole (PubMed:10856230, PubMed:11263974, PubMed:12161436, PubMed:12556516, PubMed:18930916, PubMed:2693940). ZRC1 senses zinc availability in the cytosol, which might be performed through the histidine repeat motifs, and transports zinc from the cytosol to the vacuole if zinc in cytosol is abundant, conferring resistance to zinc toxicity (PubMed:11263974). Plays a role in resistance to zinc shock resulting from sudden influx of zinc into cytoplasm when ZRT1 and ZRT2 are induced in response to zinc depletion (PubMed:11263974, PubMed:12556516)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W070", "ec_number_list": "", "go_molecular_function": "GO:0005385 zinc ion transmembrane transporter activity", "go_cellular_component": "GO:0045121 membrane raft;GO:0000329 fungal-type vacuole membrane;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0071577 zinc ion transmembrane transport;GO:0046686 response to cadmium ion;GO:0006882 intracellular zinc ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P20107-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P20133-1", "uniprot_id": "PGTB2_YEAST", "mass": 36666.0, "length": 325, "protein_name": "Geranylgeranyl transferase type-2 subunit beta", "gene_name": "BET2", "organism": "Yeast", "refseq_name": "Rab geranylgeranyltransferase BET2", "refseq_ac": "NP_015502", "gene_names_uniprotkb": "BET2; P9705.12", "gene_names_refseq": "BET2", "protein_names_uniprotkb": "Geranylgeranyl transferase type-2 subunit beta; 2.5.1.60; GGTase-II-beta; Geranylgeranyl transferase type II subunit beta; PGGT; Type II protein geranyl-geranyltransferase subunit beta; YPT1/SEC4 proteins geranylgeranyltransferase subunit beta", "protein_names_refseq": "Rab geranylgeranyltransferase BET2", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR176C); (R-SCE-6803205); (R-SCE-8873719)", "pathway_count": 3, "publication_count": 9, "publication_id_list": "14562106;17322287;1903184;2204247;24374639;2528686;33491328;8232542;9169875", "class_list": "", "function": "Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to proteins having the C-terminal -XCC or -XCXC, where both cysteines may become modified. Acts on YPT1 and SEC4., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W4H7;P32433", "ec_number_list": "2.5.1.59;2.5.1.60;2.5.1.58", "go_molecular_function": "GO:0004663 Rab geranylgeranyltransferase activity;GO:0008270 zinc ion binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005968 Rab-protein geranylgeranyltransferase complex;GO:0170069 geranylgeranyltransferase-III complex", "go_biological_process": "GO:0006612 protein targeting to membrane;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0018344 protein geranylgeranylation", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P20133-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P20424-1", "uniprot_id": "SRP54_YEAST", "mass": 59624.0, "length": 541, "protein_name": "Signal recognition particle subunit SRP54", "gene_name": "SRP54", "organism": "Yeast", "refseq_name": "RNA-binding signal recognition particle subunit SRP54", "refseq_ac": "NP_015413", "gene_names_uniprotkb": "SRP54; P9513.14; SRH1", "gene_names_refseq": "SRH1; SRP54", "protein_names_uniprotkb": "Signal recognition particle subunit SRP54; 3.6.5.4; Signal recognition particle 54 kDa protein homolog", "protein_names_refseq": "RNA-binding signal recognition particle subunit SRP54", "tax_id": 559292, "disease": "Shwachman-Diamond syndrome (Disease Ontology:DOID:0060479); severe congenital neutropenia 8 (Disease Ontology:DOID:0112135); neutropenia (Disease Ontology:DOID:1227)", "pathway": " (sce:YPR088C); (R-SCE-1799339)", "pathway_count": 2, "publication_count": 13, "publication_id_list": "10676815;19795423;19823750;21177495;2187859;22814378;24374639;2557350;33491328;7925282;8382769;8805251;9169875", "class_list": "", "function": "Signal-recognition-particle (SRP) assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum (ER) membrane. SRP is required for the cotranslational protein translocation for ER import and preferentially recognizes strongly hydrophobic signal sequences. It is involved in targeting the nascent chain-ribosome (RNC) complex to the ER and is proposed to participate in the arrest of nascent chain elongation during membrane targeting. SRP54 binds to the signal sequence of presecretory protein when they emerge from the ribosomes. SRP54 interacts with the scR1 RNA and mediates the association of the resulting SRP-RNC complex with the signal recognition particle receptor (SR) via its alpha subunit SRP101. Both, SRP54 and SRP101, are locked in their GTP bound forms in the SRP-RNC-SR complex, which dissociates upon transferring the signal sequence to the protein-conducting channel (translocon). After signal sequence transfer, SRP54 and SRP101 act as reciprocal GTPase-activating proteins (GAPs), thereby resolving their association., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W489", "ec_number_list": "3.6.5.2;3.6.5.3;3.6.5.-;3.6.5.4;3.6.5.5", "go_molecular_function": "GO:0030942 endoplasmic reticulum signal peptide binding;GO:0003924 GTPase activity;GO:0005096 GTPase activator activity;GO:0005525 GTP binding;GO:0008312 7S RNA binding", "go_cellular_component": "GO:0005786 signal recognition particle, endoplasmic reticulum targeting;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol", "go_biological_process": "GO:0006614 SRP-dependent cotranslational protein targeting to membrane;GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition;GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P20424-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P20433-1", "uniprot_id": "RPB4_YEAST", "mass": 25414.0, "length": 221, "protein_name": "DNA-directed RNA polymerase II subunit RPB4", "gene_name": "RPB4", "organism": "Yeast", "refseq_name": "DNA-directed RNA polymerase II subunit RPB4", "refseq_ac": "NP_012395", "gene_names_uniprotkb": "RPB4; J0654", "gene_names_refseq": "CTF15; RPB4", "protein_names_uniprotkb": "DNA-directed RNA polymerase II subunit RPB4; B32; DNA-directed RNA polymerase II 32 kDa polypeptide; RNA polymerase II subunit B4", "protein_names_refseq": "DNA-directed RNA polymerase II subunit RPB4", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL140W); (R-SCE-113418); (R-SCE-674695); (R-SCE-6781823); (R-SCE-6782135); (R-SCE-6782210); (R-SCE-6796648); (R-SCE-6807505); (R-SCE-72086); (R-SCE-72203); (R-SCE-73776); (R-SCE-73779); (R-SCE-75953); (R-SCE-76042); (R-SCE-77075); (R-SCE-9018519)", "pathway_count": 16, "publication_count": 28, "publication_id_list": "11087726;11382749;12411509;12746495;12857861;12914699;14580350;15304220;15591044;15610738;16341226;16357218;16765890;17056745;17322287;19779198;19795423;19823750;1985924;2041753;22218487;22814378;24374639;2674672;32597660;33491328;8641269;8813765", "class_list": "", "function": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB4 is part of a subcomplex with RPB7 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RPB4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA. The RPB4-RPB7 subcomplex is necessary for promoter-directed transcription initiation but is not required for recruitment of Pol II to active preinitiation complexes and seems to be dispensable for transcription elongation and termination. The RPB4-RPB7 subcomplex recruits FCP1 to Pol II. Involved in DNA repair of damage in the transcribed strand. RPB4 is dispensable under optimal growth conditions, but becomes essential during heat or cold shock and under nutrient depletion. Suppresses the RBP9-mediated transcription-coupled repair (TCR) subpathway of nucleotide excision repair (NER) but facilitates the RAD26-mediated TCR subpathway. Under stress conditions only, involved in mRNA export to the cytoplasm. Involved in mRNA decay. Promotes or enhances the deadenylation process of specific mRNAs and may recruit PAT1 and the LSM1-7 complex to these mRNAs, thus stimulating their decapping and further decay., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VW44", "ec_number_list": "", "go_molecular_function": "GO:0000166 nucleotide binding;GO:0031369 translation initiation factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000932 P-body;GO:0005665 RNA polymerase II, core complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0006366 transcription by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter;GO:0006368 transcription elongation by RNA polymerase II;GO:0006352 DNA-templated transcription initiation", "synthesized_glycan_count": 0, "hit_score": 2.9, "record_id": "P20433-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P20435-1", "uniprot_id": "RPAB2_YEAST", "mass": 17910.0, "length": 155, "protein_name": "DNA-directed RNA polymerases I, II, and III subunit RPABC2", "gene_name": "RPO26", "organism": "Yeast", "refseq_name": "DNA-directed RNA polymerase core subunit RPO26", "refseq_ac": "NP_015513", "gene_names_uniprotkb": "RPO26; P9677.8; RPB6", "gene_names_refseq": "RPB6; RPO26", "protein_names_uniprotkb": "DNA-directed RNA polymerases I, II, and III subunit RPABC2; ABC23; DNA-directed RNA polymerases I, II, and III 23 kDa polypeptide; RNA polymerases I, II, and III subunit ABC2", "protein_names_refseq": "DNA-directed RNA polymerase core subunit RPO26", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR187W); (R-SCE-113418); (R-SCE-674695); (R-SCE-6781823); (R-SCE-6782135); (R-SCE-6782210); (R-SCE-6796648); (R-SCE-6807505); (R-SCE-72086); (R-SCE-72203); (R-SCE-73762); (R-SCE-73772); (R-SCE-73776); (R-SCE-73779); (R-SCE-75953); (R-SCE-76042); (R-SCE-76061); (R-SCE-76066); (R-SCE-77075); (R-SCE-9018519)", "pathway_count": 20, "publication_count": 34, "publication_id_list": "10384303;11313498;11313499;11717393;11805306;11918799;12407181;12746495;12746498;12914699;14562095;14562106;14580350;14963322;15537538;15591044;15610738;16341226;16765890;16818233;18084032;18160037;18407956;19795423;19823750;2186966;2247052;24153182;24153184;24374639;30181345;33491328;33502312;9169875", "class_list": "", "function": "DNA-dependent RNA polymerases catalyze the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. RNA polymerases are composed of mobile elements that move relative to each other. In Pol II, RPB6 is part of the clamp element and together with parts of RPB1 and RPB2 forms a pocket to which the RPB4-RPB7 subcomplex binds., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W4I7", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003899 DNA-directed RNA polymerase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005665 RNA polymerase II, core complex;GO:0005736 RNA polymerase I complex", "go_biological_process": "GO:0006360 transcription by RNA polymerase I;GO:0042797 tRNA transcription by RNA polymerase III;GO:0042254 ribosome biogenesis;GO:0006366 transcription by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter", "synthesized_glycan_count": 0, "hit_score": 3.5, "record_id": "P20435-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P20447-1", "uniprot_id": "DBP3_YEAST", "mass": 58827.0, "length": 523, "protein_name": "ATP-dependent RNA helicase DBP3", "gene_name": "DBP3", "organism": "Yeast", "refseq_name": "RNA-dependent ATPase DBP3", "refseq_ac": "NP_011437", "gene_names_uniprotkb": "DBP3", "gene_names_refseq": "DBP3", "protein_names_uniprotkb": "ATP-dependent RNA helicase DBP3; 3.6.4.13; DEAD box protein 3; Helicase CA3", "protein_names_refseq": "RNA-dependent ATPase DBP3", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL078C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562095;14562106;22814378;2406722;24374639;33481703;9032262;9169869;9290212", "class_list": "", "function": "ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VU66", "ec_number_list": "3.6.4.13;5.6.2.3;3.6.4.10;3.6.-.-;5.6.2.4;3.6.4.-;5.6.1.4;3.6.4.12;3.6.4.6;5.6.2.5;3.6.1.-;2.3.2.27;3.1.-.-;3.4.24.-;3.6.5.-;2.7.4.3;2.7.11.1;7.2.2.-", "go_molecular_function": "GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003724 RNA helicase activity;GO:0008186 ATP-dependent activity, acting on RNA", "go_cellular_component": "GO:0005730 nucleolus;GO:0030687 preribosome, large subunit precursor", "go_biological_process": "GO:0006364 rRNA processing;GO:0000464 endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P20447-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P20448-1", "uniprot_id": "DBP4_YEAST", "mass": 87193.0, "length": 770, "protein_name": "ATP-dependent RNA helicase HCA4", "gene_name": "HCA4", "organism": "Yeast", "refseq_name": "RNA-dependent ATPase HCA4", "refseq_ac": "NP_012501", "gene_names_uniprotkb": "HCA4; DBP4; ECM24; J1250", "gene_names_refseq": "DBP4; ECM24; HCA4", "protein_names_uniprotkb": "ATP-dependent RNA helicase HCA4; 3.6.4.13; DEAD box protein 4; Helicase CA4; Helicase UF1", "protein_names_refseq": "RNA-dependent ATPase HCA4", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL033W)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "14562095;14562106;14690591;16209945;17287358;17322287;17330950;18407956;18833290;18975973;19779198;19795423;19823750;20702584;21177495;23749301;2406722;24374639;30516470;33481703;33491328;8641269;9199348", "class_list": "", "function": "ATP-dependent RNA helicase required for ribosome biogenesis. Involved in the release of U14 snoRNA in pre-ribosomal complexes. Required for pre-rRNA cleavage at site A2., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWF0;Q6B1G2;Q92329", "ec_number_list": "3.6.4.13;5.6.2.3;3.6.4.10;3.6.-.-;5.6.2.4;3.6.4.-;5.6.1.4;3.6.4.12;3.6.4.6;5.6.2.5;3.6.1.-;2.3.2.27;3.1.-.-;3.4.24.-;3.6.5.-;2.7.4.3;2.7.11.1;7.2.2.-", "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0016887 ATP hydrolysis activity;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0032040 small-subunit processome", "go_biological_process": "GO:0006364 rRNA processing", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P20448-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P20449-1", "uniprot_id": "DBP5_YEAST", "mass": 53874.0, "length": 482, "protein_name": "ATP-dependent RNA helicase DBP5", "gene_name": "DBP5", "organism": "Yeast", "refseq_name": "ATP-dependent RNA helicase DBP5", "refseq_ac": "NP_014689", "gene_names_uniprotkb": "DBP5; RAT8", "gene_names_refseq": "DBP5; RAT8", "protein_names_uniprotkb": "ATP-dependent RNA helicase DBP5; 3.6.4.13; DEAD box protein 5; Helicase CA5/6; Ribonucleic acid-trafficking protein 8", "protein_names_refseq": "ATP-dependent RNA helicase DBP5", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR046C)", "pathway_count": 1, "publication_count": 27, "publication_id_list": "10428971;10523319;10610322;11350039;12192043;12686617;14562095;14562106;15280434;15574330;15619606;17330950;18407956;19779198;19795423;19823750;21126336;23749301;2406722;24374639;32597660;33481703;33491328;34965436;9169874;9564047;9564048", "class_list": "", "function": "ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus. May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex. Contributes to the blocking of bulk poly(A)+ mRNA export in ethanol-stressed cells. May also be involved in early transcription., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 8, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2B2", "ec_number_list": "3.6.4.13;5.6.2.3;3.6.4.10;3.6.-.-;5.6.2.4;3.6.4.-;5.6.1.4;3.6.4.12;3.6.4.6;5.6.2.5;3.6.1.-;2.3.2.27;3.1.-.-;3.4.24.-;3.6.5.-;2.7.4.3;2.7.11.1;7.2.2.-", "go_molecular_function": "GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003724 RNA helicase activity;GO:0008186 ATP-dependent activity, acting on RNA", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0031965 nuclear membrane;GO:0010494 cytoplasmic stress granule;GO:0044614 nuclear pore cytoplasmic filaments", "go_biological_process": "GO:0016973 poly(A)+ mRNA export from nucleus;GO:0006406 mRNA export from nucleus;GO:0006409 tRNA export from nucleus;GO:0006415 translational termination;GO:0015031 protein transport", "synthesized_glycan_count": 0, "hit_score": 2.8, "record_id": "P20449-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P20457-1", "uniprot_id": "PRI2_YEAST", "mass": 62263.0, "length": 528, "protein_name": "DNA primase large subunit", "gene_name": "PRI2", "organism": "Yeast", "refseq_name": "DNA primase subunit PRI2", "refseq_ac": "NP_012879", "gene_names_uniprotkb": "PRI2; YKL258", "gene_names_refseq": "PRI2", "protein_names_uniprotkb": "DNA primase large subunit; DNA polymerase alpha:primase complex p58 subunit; DNA polymerase-primase complex p58 subunit; DNA primase 58 kDa subunit; Pol alpha-primase complex p58 subunit", "protein_names_refseq": "DNA primase subunit PRI2", "tax_id": 559292, "disease": "", "pathway": " (sce:YKL045W); (R-SCE-113501); (R-SCE-68952); (R-SCE-68962); (R-SCE-69091); (R-SCE-69166); (R-SCE-69183)", "pathway_count": 7, "publication_count": 10, "publication_id_list": "16675460;17704817;2023935;20404922;24374639;2528682;3061469;33491328;8154189;8196765", "class_list": "", "function": "DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. In a complex with DNA polymerase alpha (DNA polymerase alpha:primase) constitutes a replicative polymerase. Both primase components participate in formation of the active center, but the ATP-binding site is exclusively located on p48., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXP2", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding", "go_cellular_component": "GO:0005658 alpha DNA polymerase:primase complex;GO:0005634 nucleus;GO:0005635 nuclear envelope", "go_biological_process": "GO:0006260 DNA replication;GO:0006302 double-strand break repair;GO:0006270 DNA replication initiation;GO:0006269 DNA replication, synthesis of primer", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P20457-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P20459-1", "uniprot_id": "IF2A_YEAST", "mass": 34718.0, "length": 304, "protein_name": "Eukaryotic translation initiation factor 2 subunit alpha", "gene_name": "SUI2", "organism": "Yeast", "refseq_name": "translation initiation factor eIF2 subunit alpha", "refseq_ac": "NP_012540", "gene_names_uniprotkb": "SUI2; J1429; TIF211", "gene_names_refseq": "SUI2", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 2 subunit alpha; eIF-2-alpha; eIF-2A; eIF-2alpha; eIF2-alpha", "protein_names_refseq": "translation initiation factor eIF2 subunit alpha", "tax_id": 559292, "disease": "alcohol-associated liver disease (Disease Ontology:DOID:0070658); leukodystrophy (Disease Ontology:DOID:10579); Alzheimer's disease (Disease Ontology:DOID:10652); transient cerebral ischemia (Disease Ontology:DOID:224); middle cerebral artery infarction (Disease Ontology:DOID:3525)", "pathway": " (sce:YJR007W); (R-SCE-156827); (R-SCE-382556); (R-SCE-72649); (R-SCE-72695); (R-SCE-72702); (R-SCE-72731); (R-SCE-9840373)", "pathway_count": 8, "publication_count": 33, "publication_id_list": "10733573;11756670;11875433;14562106;14607111;16179258;17322287;1739968;18407956;19684113;19779198;19795423;19823750;20702584;23749301;23775072;24374639;2649894;30516470;30517694;31048492;32027465;32597660;33481703;33491328;34965436;35031321;37507029;7742363;8035796;8336737;8641269;8798780", "class_list": "", "function": "eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF2B., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 27, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWI2;E9P8T6", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0043022 ribosome binding;GO:0003743 translation initiation factor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005840 ribosome;GO:0010494 cytoplasmic stress granule;GO:0033290 eukaryotic 48S preinitiation complex", "go_biological_process": "GO:0006413 translational initiation;GO:0001731 formation of translation preinitiation complex", "synthesized_glycan_count": 0, "hit_score": 3.4, "record_id": "P20459-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P20485-1", "uniprot_id": "KICH_YEAST", "mass": 66317.0, "length": 582, "protein_name": "Choline kinase", "gene_name": "CKI1", "organism": "Yeast", "refseq_name": "bifunctional choline kinase/ethanolamine kinase CKI1", "refseq_ac": "NP_013234", "gene_names_uniprotkb": "CKI1; CKI; L3130; L9606.8", "gene_names_refseq": "CKI1", "protein_names_uniprotkb": "Choline kinase; 2.7.1.32; ATP:choline phosphotransferase", "protein_names_refseq": "bifunctional choline kinase/ethanolamine kinase CKI1", "tax_id": 559292, "disease": "colon adenoma (Disease Ontology:DOID:0050912); megaconial type congenital muscular dystrophy (Disease Ontology:DOID:0110632); intellectual disability (Disease Ontology:DOID:1059); microcephaly (Disease Ontology:DOID:10907); epilepsy (Disease Ontology:DOID:1826); colon cancer (Disease Ontology:DOID:219); transient cerebral ischemia (Disease Ontology:DOID:224); recurrent hypersomnia (Disease Ontology:DOID:8619); narcolepsy (Disease Ontology:DOID:8986); muscular dystrophy (Disease Ontology:DOID:9884)", "pathway": " (sce:YLR133W); (R-SCE-1483191); (R-SCE-1483213)", "pathway_count": 3, "publication_count": 29, "publication_id_list": "10329685;11078727;12105205;14562095;14562106;15665377;15919656;17322287;17330950;17563356;18086883;18407956;19684113;19779198;20489023;20702584;21078689;21126336;21177495;23749301;24374639;2536698;30516470;32597660;33229814;33481703;33491328;9169871;9506987", "class_list": "", "function": "Catalyzes the committed step in the synthesis of phosphatidylcholine by the CDP-choline pathway (PubMed:10329685, PubMed:2536698, PubMed:9506987). Also exhibits ethanolamine kinase activity but it is a poor substrate at 14% efficiency compared with choline (PubMed:2536698, PubMed:9506987)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 26, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 10, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VYC8", "ec_number_list": "2.7.1.32;2.7.1.82", "go_molecular_function": "GO:0005524 ATP binding;GO:0004103 choline kinase activity;GO:0004305 ethanolamine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006656 phosphatidylcholine biosynthetic process;GO:0006646 phosphatidylethanolamine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 3.4, "record_id": "P20485-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P20604-1", "uniprot_id": "PP11_YEAST", "mass": 35538.0, "length": 311, "protein_name": "Serine/threonine-protein phosphatase PP1-1", "gene_name": "SIT4", "organism": "Yeast", "refseq_name": "type 2A-related serine/threonine-protein phosphatase SIT4", "refseq_ac": "NP_010236", "gene_names_uniprotkb": "SIT4; D2693; PPH1", "gene_names_refseq": "PPH1; SIT4", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase PP1-1; 3.1.3.16", "protein_names_refseq": "type 2A-related serine/threonine-protein phosphatase SIT4", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL047W); (R-SCE-204005)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "12820961;14551259;14562106;15447631;15689491;1848673;20489023;24374639;2537149;33491328;9169867", "class_list": "", "function": "Involved in the dephosphorylation of the large subunit of RNA polymerase II. Is required in late G1 for normal G1 cyclin expression, bud initiation and expression of certain genes that are periodically expressed during late G1. Associates with the SAP proteins in a cell cycle-dependent manner., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRU8", "ec_number_list": "3.1.3.16;3.1.3.43;3.1.3.48", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000159 protein phosphatase type 2A complex", "go_biological_process": "GO:0006281 DNA repair;GO:0032956 regulation of actin cytoskeleton organization;GO:0035556 intracellular signal transduction;GO:0051301 cell division;GO:0034599 cellular response to oxidative stress", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P20604-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P20606-1", "uniprot_id": "SAR1_YEAST", "mass": 21451.0, "length": 190, "protein_name": "Small COPII coat GTPase SAR1", "gene_name": "SAR1", "organism": "Yeast", "refseq_name": "Arf family GTPase SAR1", "refseq_ac": "NP_015106", "gene_names_uniprotkb": "SAR1", "gene_names_refseq": "SAR1", "protein_names_uniprotkb": "Small COPII coat GTPase SAR1; 3.6.5.-; GTP-binding protein SAR1; Secretion-associated RAS-related protein 1", "protein_names_refseq": "Arf family GTPase SAR1", "tax_id": 559292, "disease": "chylomicron retention disease (Disease Ontology:DOID:0060357)", "pathway": " (sce:YPL218W); (R-SCE-204005); (R-SCE-5694530); (R-SCE-983170)", "pathway_count": 4, "publication_count": 39, "publication_id_list": "10720463;11389436;11560939;12235121;12239560;12671686;12912905;14627716;15665868;16107716;18407956;1907491;1907973;1907974;1922074;19779198;20702584;21126336;22106047;23749301;24374639;2512296;30516470;32597660;33481703;33491328;7822237;8106544;8419365;8451644;8530490;8548805;8889833;9023343;9169875;9428766;9568718;9685263;9756629", "class_list": "", "function": "Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. SAR1 controls the coat assembly in a stepwise manner. Activated SAR1-GTP by SEC12 binds to membranes first and recruits the SEC23/24 complex. These SEC23/24-SAR1 prebudding intermediates are then collected by the SEC13/31 complex as subunits polymerize to form coated transport vesicles. Conversion to SAR1-GDP triggers coat release and recycles COPII subunits., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 8, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3F2", "ec_number_list": "3.6.5.2;3.6.5.3;3.6.5.-;3.6.5.4;3.6.5.5", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0044233 mitochondria-associated endoplasmic reticulum membrane contact site", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0061024 membrane organization;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0016050 vesicle organization;GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 4.0, "record_id": "P20606-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P20676-1", "uniprot_id": "NUP1_YEAST", "mass": 113581.0, "length": 1076, "protein_name": "Nucleoporin NUP1", "gene_name": "NUP1", "organism": "Yeast", "refseq_name": "FG-nucleoporin NUP1", "refseq_ac": "NP_014741", "gene_names_uniprotkb": "NUP1; YOR3182C", "gene_names_refseq": "NUP1", "protein_names_uniprotkb": "Nucleoporin NUP1; Nuclear pore protein NUP1", "protein_names_refseq": "FG-nucleoporin NUP1", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR098C)", "pathway_count": 1, "publication_count": 39, "publication_id_list": "10525531;10684247;11046143;11387327;11535617;11867631;12372823;12543930;12604785;12791264;12917401;14562106;14574415;15039779;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20190278;20702584;20702586;21126336;21177495;2190694;22031224;22814378;23645671;23749301;24374639;28265048;32597660;33229814;33481703;33491328;9169874;9200815", "class_list": "", "function": "Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope (GSP1 and GSP2 GTPases associated predominantly with GTP in the nucleus, with GDP in the cytoplasm). As one of the FG repeat nucleoporins NUP1 is involved in interactions with and guidance of nuclear transport receptors such as SRP1-KAP95 (importin alpha and beta) through the NPC. Like the closely related NUP2 it also plays an important role in disassembling and recycling SRP1-KAP95 to the cytoplasm after nuclear import. Upon entry of the heterotrimeric SRP1-KAP95-cargo complex in the nucleus, NUP1 binds through its C-terminus to KAP95, thus accelerating the release of KAP95 and, indirectly, of the nuclear localization signal (NLS)-containing cargo from the SRP1-KAP95-cargo complex., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 8, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 8, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 8, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 80, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "D6W2F9", "ec_number_list": "", "go_molecular_function": "GO:0017056 structural constituent of nuclear pore;GO:0008139 nuclear localization sequence binding", "go_cellular_component": "GO:0044615 nuclear pore nuclear basket;GO:0005635 nuclear envelope;GO:0005643 nuclear pore;GO:0031965 nuclear membrane;GO:0044613 nuclear pore central transport channel", "go_biological_process": "GO:0016973 poly(A)+ mRNA export from nucleus;GO:0000055 ribosomal large subunit export from nucleus;GO:0006913 nucleocytoplasmic transport;GO:0006607 NLS-bearing protein import into nucleus;GO:0006405 RNA export from nucleus", "synthesized_glycan_count": 0, "hit_score": 4.9, "record_id": "P20676-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P20840-1", "uniprot_id": "SAG1_YEAST", "mass": 70340.0, "length": 650, "protein_name": "Alpha-agglutinin", "gene_name": "SAG1", "organism": "Yeast", "refseq_name": "Sag1p", "refseq_ac": "NP_012537", "gene_names_uniprotkb": "SAG1; AGAL1; J1418", "gene_names_refseq": "AG(ALPHA)1; SAG1", "protein_names_uniprotkb": "Alpha-agglutinin; AG-alpha-1", "protein_names_refseq": "Sag1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR004C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "11292808;24374639;2676603;2677666;7592821;7844147;8007981;8455628;8641269;8741846;9613572", "class_list": "", "function": "Cell surface glycoprotein promoting cell-cell contact to facilitate mating. S.cerevisiae A and alpha cells express the complementary cell surface glycoproteins A-agglutinin and alpha-, respectively, which interact with one another to promote cellular aggregation during mating., [UniProtKB, PubMed]", "predicted_glycosites": 8, "predicted_n_glycosites": 8, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 2, "reported_o_glycosites": 23, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 2, "total_reported_o_glycosites": 23, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 2, "total_o_glycosites": 23, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 27, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 33, "binding_glycan_count": 0, "secondary_ac_list": "D6VWH8", "ec_number_list": "", "go_molecular_function": "GO:0050839 cell adhesion molecule binding", "go_cellular_component": "GO:0071944 cell periphery;GO:0000324 fungal-type vacuole;GO:0009277 fungal-type cell wall;GO:0098552 side of membrane", "go_biological_process": "GO:0000752 agglutination involved in conjugation with cellular fusion", "synthesized_glycan_count": 0, "hit_score": 3.7, "record_id": "P20840-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P20967-1", "uniprot_id": "ODO1_YEAST", "mass": 114416.0, "length": 1014, "protein_name": "2-oxoglutarate dehydrogenase, mitochondrial", "gene_name": "KGD1", "organism": "Yeast", "refseq_name": "alpha-ketoglutarate dehydrogenase KGD1", "refseq_ac": "NP_012141", "gene_names_uniprotkb": "KGD1; OGD1", "gene_names_refseq": "KGD1; OGD1", "protein_names_uniprotkb": "2-oxoglutarate dehydrogenase, mitochondrial; 1.2.4.2; 2-oxoglutarate dehydrogenase complex component E1; Alpha-ketoglutarate dehydrogenase complex subunit E1; OGDC-E1; OGDHC subunit E1; OGDH; alpha-KGDHC subunit E1", "protein_names_refseq": "alpha-ketoglutarate dehydrogenase KGD1", "tax_id": 559292, "disease": "Yoon-Bellen neurodevelopmental syndrome (Disease Ontology:DOID:0070468); oxoglutarate dehydrogenase deficiency (Disease Ontology:DOID:0081326); dilated cardiomyopathy (Disease Ontology:DOID:12930)", "pathway": " (sce:YIL125W); (R-SCE-6783984); (R-SCE-9837999); (R-SCE-9853506)", "pathway_count": 4, "publication_count": 20, "publication_id_list": "11926067;14562095;14562106;14576278;15665377;17330950;18407956;19779198;19795423;19823750;2072900;21126336;22218487;24374639;2503710;25165143;32597660;33491328;8299151;9169870", "class_list": "", "function": "The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVG2", "ec_number_list": "3.5.3.1;7.1.2.2;2.3.3.1;4.2.1.2;1.8.1.4;3.6.4.10;4.98.1.1;2.3.1.61;4.2.1.3;1.2.4.2;1.1.1.37;1.2.4.1;3.4.21.53;2.3.1.41;1.2.1.4;1.2.1.5;6.1.1.5;2.3.3.10", "go_molecular_function": "GO:0046872 metal ion binding;GO:0030976 thiamine pyrophosphate binding;GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0042645 mitochondrial nucleoid;GO:0045252 oxoglutarate dehydrogenase complex", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0006103 2-oxoglutarate metabolic process;GO:0045333 cellular respiration", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P20967-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P21147-1", "uniprot_id": "ACO1_YEAST", "mass": 58403.0, "length": 510, "protein_name": "Acyl-CoA desaturase 1", "gene_name": "OLE1", "organism": "Yeast", "refseq_name": "stearoyl-CoA 9-desaturase", "refseq_ac": "NP_011460", "gene_names_uniprotkb": "OLE1", "gene_names_refseq": "MDM2; OLE1", "protein_names_uniprotkb": "Acyl-CoA desaturase 1; 1.14.19.1; Delta 9 fatty acid desaturase; Fatty acid desaturase 1; Stearoyl-CoA desaturase 1", "protein_names_refseq": "stearoyl-CoA 9-desaturase", "tax_id": 559292, "disease": "metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); metabolic dysfunction-associated steatohepatitis (Disease Ontology:DOID:0080547); autosomal dominant nonsyndromic deafness 79 (Disease Ontology:DOID:0112160); hyperinsulinism (Disease Ontology:DOID:2018); carcinoma (Disease Ontology:DOID:305); restrictive cardiomyopathy (Disease Ontology:DOID:397)", "pathway": " (sce:YGL055W); (R-SCE-75105)", "pathway_count": 2, "publication_count": 14, "publication_id_list": "16443825;16847258;17322287;1978720;22323296;24374639;2674136;26928762;32597660;33481703;33491328;7947684;9169869;9234674", "class_list": "", "function": "Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates (PubMed:1978720, PubMed:7947684). Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (PubMed:1978720, PubMed:2674136). Required for the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (PubMed:16443825, PubMed:1978720, PubMed:7947684). Regulates fatty acid desaturation, that is, the ratio of unsaturated versus saturated fatty acyl chains, by competing with the acyltransferase STC1 for the common substrate C16:0-CoA. SCT1 sequesters C16:0-CoA into lipids, thereby shielding it from desaturation by OLE1 (PubMed:22323296)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VU86;E9P911", "ec_number_list": "1.14.19.1", "go_molecular_function": "GO:0005506 iron ion binding;GO:0009055 electron transfer activity;GO:0004768 stearoyl-CoA 9-desaturase activity;GO:0020037 heme binding;GO:0032896 palmitoyl-CoA 9-desaturase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006636 unsaturated fatty acid biosynthetic process;GO:0000001 mitochondrion inheritance", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P21147-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P21182-1", "uniprot_id": "DCAM_YEAST", "mass": 46232.0, "length": 396, "protein_name": "S-adenosylmethionine decarboxylase proenzyme", "gene_name": "SPE2", "organism": "Yeast", "refseq_name": "adenosylmethionine decarboxylase SPE2", "refseq_ac": "NP_014590", "gene_names_uniprotkb": "SPE2; O1275", "gene_names_refseq": "SPE2", "protein_names_uniprotkb": "S-adenosylmethionine decarboxylase proenzyme; 4.1.1.50; AdoMetDC; SAMDC", "protein_names_refseq": "adenosylmethionine decarboxylase SPE2", "tax_id": 559292, "disease": "prostate cancer (Disease Ontology:DOID:10283); lung non-small cell carcinoma (Disease Ontology:DOID:3908)", "pathway": " (sce:YOL052C); (R-SCE-351202)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "14562106;2266128;24374639;33491328;8789261;9169874", "class_list": "", "function": "Catalyzes the decarboxylation of S-adenosylmethionine, a key step in the biosynthetic pathway for spermidine and spermine. It is essential for normal growth, sporulation, and maintenance of ds-RNA virus., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W216", "ec_number_list": "4.1.1.50", "go_molecular_function": "GO:0004014 adenosylmethionine decarboxylase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006597 spermine biosynthetic process;GO:0008295 spermidine biosynthetic process;GO:0015940 pantothenate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P21182-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P21190-1", "uniprot_id": "IME1_YEAST", "mass": 41858.0, "length": 360, "protein_name": "Meiosis-inducing protein 1", "gene_name": "IME1", "organism": "Yeast", "refseq_name": "transcription factor IME1", "refseq_ac": "NP_012627", "gene_names_uniprotkb": "IME1; J1916", "gene_names_refseq": "IME1", "protein_names_uniprotkb": "Meiosis-inducing protein 1", "protein_names_refseq": "transcription factor IME1", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR094C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "15282298;2247050;24269006;24374639;8483452;8641269", "class_list": "", "function": "Transcription factor required for sporulation and for early sporulation-specific genes expression. Positive regulator of SME1/IME2 expression. Directly activates expression of SLZ1 during meiosis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWR2", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0051321 meiotic cell cycle;GO:0040020 regulation of meiotic nuclear division", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P21190-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P21192-1", "uniprot_id": "ACE2_YEAST", "mass": 86634.0, "length": 770, "protein_name": "Metallothionein expression activator", "gene_name": "ACE2", "organism": "Yeast", "refseq_name": "DNA-binding transcription factor ACE2", "refseq_ac": "NP_013232", "gene_names_uniprotkb": "ACE2; L3123; L9606.10", "gene_names_refseq": "ACE2", "protein_names_uniprotkb": "Metallothionein expression activator", "protein_names_refseq": "DNA-binding transcription factor ACE2", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR131C)", "pathway_count": 1, "publication_count": 29, "publication_id_list": "11875433;14562106;15200949;15665377;17287358;17330950;17563356;18407956;18715118;19684113;19779198;19795423;19823750;1986241;20489023;20573982;20702584;21177495;22218487;23749301;24374639;24493588;24909858;30516470;32597660;33229814;33481703;33491328;9169871", "class_list": "", "function": "Plays a role in regulating basal-level expression of CUP1. Activates EGT2 transcription in the absence of SWI5., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 65, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VYC6", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987 cis-regulatory region sequence-specific DNA binding;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0000082 G1/S transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 3.4, "record_id": "P21192-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P21242-1", "uniprot_id": "PSA7_YEAST", "mass": 31536.0, "length": 288, "protein_name": "Probable proteasome subunit alpha type-7", "gene_name": "PRE10", "organism": "Yeast", "refseq_name": "proteasome core particle subunit alpha 7", "refseq_ac": "NP_015007", "gene_names_uniprotkb": "PRE10; O6650; PRC1; PRS1", "gene_names_refseq": "PRE10", "protein_names_uniprotkb": "Probable proteasome subunit alpha type-7; Macropain subunit C1; Multicatalytic endopeptidase complex subunit C1; Proteasome component C1; Proteinase YSCE subunit 1", "protein_names_refseq": "proteasome core particle subunit alpha 7", "tax_id": 559292, "disease": "neurodegenerative disease (Disease Ontology:DOID:1289)", "pathway": " (sce:YOR362C); (R-SCE-1236974); (R-SCE-1236978); (R-SCE-5668541); (R-SCE-5689880); (R-SCE-9907900); (R-SCE-9912633)", "pathway_count": 7, "publication_count": 21, "publication_id_list": "11062564;11081519;14562106;15464721;16531229;16608349;16793518;1697860;18407956;19795423;19823750;20227375;20486117;21126336;22814378;22927375;23749301;24374639;33491328;9087403;9169874", "class_list": "", "function": "The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W357", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0034515 proteasome storage granule;GO:0005634 nucleus;GO:0019773 proteasome core complex, alpha-subunit complex", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0010499 proteasomal ubiquitin-independent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P21242-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P21243-1", "uniprot_id": "PSA1_YEAST", "mass": 28001.0, "length": 252, "protein_name": "Proteasome subunit alpha type-1", "gene_name": "SCL1", "organism": "Yeast", "refseq_name": "proteasome core particle subunit alpha 1", "refseq_ac": "NP_011504", "gene_names_uniprotkb": "SCL1; PRC2; PRS2", "gene_names_refseq": "PRC2; SCL1", "protein_names_uniprotkb": "Proteasome subunit alpha type-1; Macropain subunit C7-alpha; Multicatalytic endopeptidase complex C7; Proteasome component C7-alpha; Proteasome component Y8; Proteinase YSCE subunit 7; SCL1 suppressor protein", "protein_names_refseq": "proteasome core particle subunit alpha 1", "tax_id": 559292, "disease": "myocardial infarction (Disease Ontology:DOID:5844)", "pathway": " (sce:YGL011C); (R-SCE-1236974); (R-SCE-1236978); (R-SCE-5668541); (R-SCE-5689880); (R-SCE-9907900); (R-SCE-9912633)", "pathway_count": 7, "publication_count": 24, "publication_id_list": "11062564;11081519;11493007;11500370;14562095;14562106;16531229;16608349;16793518;1697860;18407956;1882553;1898763;20227375;20486117;22106047;22814378;22927375;24374639;2684789;33481703;33491328;9087403;9169869", "class_list": "", "function": "The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUC6;P15708", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0019773 proteasome core complex, alpha-subunit complex", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0010499 proteasomal ubiquitin-independent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "P21243-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P21306-1", "uniprot_id": "ATP5E_YEAST", "mass": 6743.0, "length": 62, "protein_name": "ATP synthase subunit epsilon, mitochondrial", "gene_name": "ATP15", "organism": "Yeast", "refseq_name": "F1F0 ATP synthase subunit epsilon", "refseq_ac": "NP_015052", "gene_names_uniprotkb": "ATP15; P0345", "gene_names_refseq": "ATP15", "protein_names_uniprotkb": "ATP synthase subunit epsilon, mitochondrial; ATPase subunit epsilon", "protein_names_refseq": "F1F0 ATP synthase subunit epsilon", "tax_id": 559292, "disease": "mitochondrial complex V (ATP synthase) deficiency nuclear type 3 (Disease Ontology:DOID:0060332)", "pathway": " (sce:YPL271W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562106;17322287;17761666;1985960;24374639;33481703;8416924;9169875", "class_list": "", "function": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W399", "ec_number_list": "", "go_molecular_function": "GO:0046933 proton-transporting ATP synthase activity, rotational mechanism", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0045259 proton-transporting ATP synthase complex", "go_biological_process": "GO:0015986 proton motive force-driven ATP synthesis;GO:0042776 proton motive force-driven mitochondrial ATP synthesis", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P21306-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P21372-1", "uniprot_id": "PRP5_YEAST", "mass": 96359.0, "length": 849, "protein_name": "Pre-mRNA-processing ATP-dependent RNA helicase PRP5", "gene_name": "PRP5", "organism": "Yeast", "refseq_name": "DEAD-box RNA helicase PRP5", "refseq_ac": "NP_009796", "gene_names_uniprotkb": "PRP5; RNA5; YBR1603", "gene_names_refseq": "PRP5; RNA5", "protein_names_uniprotkb": "Pre-mRNA-processing ATP-dependent RNA helicase PRP5; 3.6.4.13", "protein_names_refseq": "DEAD-box RNA helicase PRP5", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR237W)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "11927574;14562095;14562106;14610285;16314500;17322287;21126336;2349233;23749301;24374639;33481703;33491328;7813418;8065365;8405998;8622683;8969184;8969185", "class_list": "", "function": "ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQN3", "ec_number_list": "3.6.4.13;5.6.2.3;3.6.4.10;3.6.-.-;5.6.2.4;3.6.4.-;5.6.1.4;3.6.4.12;3.6.4.6;5.6.2.5;3.6.1.-;2.3.2.27;3.1.-.-;3.4.24.-;3.6.5.-;2.7.4.3;2.7.11.1;7.2.2.-", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003676 nucleic acid binding;GO:0003724 RNA helicase activity;GO:0008186 ATP-dependent activity, acting on RNA", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0000348 mRNA branch site recognition", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P21372-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P21373-1", "uniprot_id": "UTR1_YEAST", "mass": 59469.0, "length": 530, "protein_name": "NAD(+) kinase", "gene_name": "UTR1", "organism": "Yeast", "refseq_name": "NADH/NAD(+) kinase", "refseq_ac": "NP_012583", "gene_names_uniprotkb": "UTR1; J1655", "gene_names_refseq": "UTR1", "protein_names_uniprotkb": "NAD(+) kinase; 2.7.1.23; Unknown transcript 1 protein", "protein_names_refseq": "NADH/NAD(+) kinase", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR049C); (R-SCE-196807)", "pathway_count": 2, "publication_count": 16, "publication_id_list": "11425472;14562106;17287358;17322287;17563356;18407956;19779198;2158927;22814378;23749301;24374639;32597660;33481703;33491328;7975898;8641269", "class_list": "", "function": "Specifically phosphorylates NAD in the presence of ATP, dATP, or CTP as phosphoryl donors., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 23, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWM0;E9P8Y8;Q54AD8", "ec_number_list": "2.7.1.23", "go_molecular_function": "GO:0003951 NAD+ kinase activity;GO:0005524 ATP binding;GO:0042736 NADH kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006741 NADP+ biosynthetic process;GO:0006879 intracellular iron ion homeostasis;GO:0019674 NAD+ metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P21373-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P21374-1", "uniprot_id": "ISY1_YEAST", "mass": 28024.0, "length": 235, "protein_name": "Pre-mRNA-splicing factor ISY1", "gene_name": "ISY1", "organism": "Yeast", "refseq_name": "Isy1p", "refseq_ac": "NP_012584", "gene_names_uniprotkb": "ISY1; J1657; NTC30; UTR3", "gene_names_refseq": "ISY1; NTC30; UTR3", "protein_names_uniprotkb": "Pre-mRNA-splicing factor ISY1; Interactor of SYF1; PRP19-associated complex protein 30", "protein_names_refseq": "Isy1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR050W); (R-SCE-6782135); (R-SCE-6782210)", "pathway_count": 3, "publication_count": 17, "publication_id_list": "10094305;11018040;11102353;11842115;11884590;12088152;12384582;14562095;14562106;14690591;17322287;21126336;2158927;24374639;33491328;7975898;8641269", "class_list": "", "function": "Involved in pre-mRNA splicing and cell cycle control. As a component of the NTC complex (or PRP19-associated complex), associates to the spliceosome to mediate conformational rearrangement or to stabilize the structure of the spliceosome after U4 snRNA dissociation, which leads to spliceosome maturation. The cell cycle arrest of SYF2 defective cells may be due to the inefficient splicing of TUB1. Also involved in DNA repair., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWM1", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0071013 catalytic step 2 spliceosome;GO:0071014 post-mRNA release spliceosomal complex;GO:0071006 U2-type catalytic step 1 spliceosome;GO:0071007 U2-type catalytic step 2 spliceosome", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0000350 generation of catalytic spliceosome for second transesterification step;GO:0000389 mRNA 3'-splice site recognition", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P21374-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P21375-1", "uniprot_id": "OSM1_YEAST", "mass": 55065.0, "length": 501, "protein_name": "Fumarate reductase 2", "gene_name": "OSM1", "organism": "Yeast", "refseq_name": "fumarate reductase", "refseq_ac": "NP_012585", "gene_names_uniprotkb": "OSM1; J1659", "gene_names_refseq": "OSM1", "protein_names_uniprotkb": "Fumarate reductase 2; 1.3.1.6; FRDS2; NADH-dependent fumarate reductase; Osmotic sensitivity protein 1; Soluble fumarate reductase, mitochondrial isozyme", "protein_names_refseq": "fumarate reductase", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR051W)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "12949191;14562106;17345583;18407956;211068;2158927;24374639;33481703;33491328;7975898;8641269;9587404;9711846", "class_list": "", "function": "Irreversibly catalyzes the reduction of fumarate to succinate. Together with the second isozyme of soluble fumarate reductase (FRD1), essential for anaerobic growth. Involved in maintaining redox balance during oxygen deficiency conditions. Reduction of fumarate is the main source of succinate during fermentation, and under anaerobic conditions, the formation of succinate is strictly required for the reoxidation of FADH(2)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWM2", "ec_number_list": "1.3.1.6", "go_molecular_function": "GO:0010181 FMN binding;GO:0016156 fumarate reductase (NADH) activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0034975 protein folding in endoplasmic reticulum;GO:0046443 FAD metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P21375-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P21538-1", "uniprot_id": "REB1_YEAST", "mass": 91874.0, "length": 810, "protein_name": "DNA-binding protein REB1", "gene_name": "REB1", "organism": "Yeast", "refseq_name": "DNA-binding protein REB1", "refseq_ac": "NP_009605", "gene_names_uniprotkb": "REB1; GRF2; YBR0502", "gene_names_refseq": "EBF1; GRF2; REB1", "protein_names_uniprotkb": "DNA-binding protein REB1; QBP", "protein_names_refseq": "DNA-binding protein REB1", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR049C)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "11258704;12200417;14562106;15542864;15665377;17330950;17563356;18407956;19779198;19795423;19823750;21126336;21177495;2204808;23749301;24374639;30516470;32597660;33481703;33491328;7597852;7813418", "class_list": "", "function": "DNA-binding protein that recognizes sites within both the enhancer and the promoter of rRNA transcription, as well as upstream of many genes transcribed by RNA polymerase II. It is essential for cell growth. May stimulate or inhibit transcription. Specifically recognizes the sequence 5'-CCGGGTA-3' or 5'-CGGGTRR-3' (where R is any purine). A member of the general regulatory factors (GRFs) which act as genome partitioners. Acts as a chromatin insulator which are known as STARs (Subtelomeric anti-silencing region). STARs prevent negative or positive transcription influence by extending across chromatin to a promoter., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 31, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VQ49", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0000976 transcription cis-regulatory region binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0043565 sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0000785 chromatin", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0006369 termination of RNA polymerase II transcription;GO:0001174 transcriptional start site selection at RNA polymerase II promoter", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "P21538-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P21560-1", "uniprot_id": "CBP3_YEAST", "mass": 39084.0, "length": 335, "protein_name": "Protein CBP3, mitochondrial", "gene_name": "CBP3", "organism": "Yeast", "refseq_name": "Cbp3p", "refseq_ac": "NP_015109", "gene_names_uniprotkb": "CBP3; P1775", "gene_names_refseq": "CBP3", "protein_names_uniprotkb": "Protein CBP3, mitochondrial", "protein_names_refseq": "Cbp3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL215W); (R-SCE-9865878)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "11522252;14562106;24374639;2544586;33491328;9169875", "class_list": "", "function": "Chaperone required for the assembly of ubiquinol-cytochrome c reductase of the mitochondrial respiratory chain., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3F5", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0043022 ribosome binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0031966 mitochondrial membrane;GO:0005761 mitochondrial ribosome;GO:0061671 Cbp3p-Cbp6 complex", "go_biological_process": "GO:0050821 protein stabilization;GO:0034551 mitochondrial respiratory chain complex III assembly;GO:0070131 positive regulation of mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P21560-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P21576-1", "uniprot_id": "VPS1_YEAST", "mass": 78737.0, "length": 704, "protein_name": "Vacuolar protein sorting-associated protein 1", "gene_name": "VPS1", "organism": "Yeast", "refseq_name": "dynamin-like GTPase VPS1", "refseq_ac": "NP_012926", "gene_names_uniprotkb": "VPS1; LAM1; SPO15", "gene_names_refseq": "GRD1; LAM1; SPO15; VPL1; VPS1; VPT26", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 1", "protein_names_refseq": "dynamin-like GTPase VPS1", "tax_id": 559292, "disease": "lethal congenital contracture syndrome (Disease Ontology:DOID:0060558); Charcot-Marie-Tooth disease dominant intermediate B (Disease Ontology:DOID:0110197); centronuclear myopathy 1 (Disease Ontology:DOID:0111223); developmental and epileptic encephalopathy (Disease Ontology:DOID:0112202); prostate cancer (Disease Ontology:DOID:10283); Human papillomavirus infectious disease (Disease Ontology:DOID:11166); microcytic anemia (Disease Ontology:DOID:11252); respiratory syncytial virus infectious disease (Disease Ontology:DOID:1273); hereditary spastic paraplegia (Disease Ontology:DOID:2476); liver disease (Disease Ontology:DOID:409); avian influenza (Disease Ontology:DOID:4492); myocardial infarction (Disease Ontology:DOID:5844); alopecia areata (Disease Ontology:DOID:986)", "pathway": " (sce:YKR001C); (R-SCE-169911); (R-SCE-75153)", "pathway_count": 3, "publication_count": 25, "publication_id_list": "1441752;14562106;15665377;17563356;1825352;18407956;19779198;19795423;19823750;20702584;2112425;21126336;21177495;22218487;23749301;24374639;26711254;27821475;31009484;32597660;33229814;33481703;33491328;8196765;8344247", "class_list": "", "function": "Essential for protein sorting in meiotic cell division of S.cerevisiae; it binds microtubules. Could also be involved in microtubule-associated motility. Necessary for membrane protein retention in a late Golgi compartment. Interacts with the MVP1 protein., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 4, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 4, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 4, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 13, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VXT7", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0008017 microtubule binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0005777 peroxisome;GO:0005829 cytosol", "go_biological_process": "GO:0007034 vacuolar transport;GO:0045053 protein retention in Golgi apparatus;GO:0000045 autophagosome assembly;GO:0006897 endocytosis;GO:0016559 peroxisome fission", "synthesized_glycan_count": 0, "hit_score": 3.1, "record_id": "P21576-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P21651-1", "uniprot_id": "RE107_YEAST", "mass": 35683.0, "length": 314, "protein_name": "Recombination protein 107", "gene_name": "REC107", "organism": "Yeast", "refseq_name": "Rec107p", "refseq_ac": "NP_012555", "gene_names_uniprotkb": "REC107; J1462; MER2", "gene_names_refseq": "MER2; REC107", "protein_names_uniprotkb": "Recombination protein 107; Meiotic recombination protein 2", "protein_names_refseq": "Rec107p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR021C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14992724;1545806;16783010;18245450;18245451;1840507;2203538;24374639;7781779;8641269", "class_list": "", "function": "Essential for meiotic chromosome segregation. MER1 and MER2 proteins must interact directly or indirectly. MER1 might be responsible for regulating the MER2 gene and/or gene product. MER2 is not required for mitosis and mitotic DNA repair mechanisms. Component of the MER2-MEI4-REC114 complex which seems to be required for meiotic double-strand break (DSB) formation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWJ5", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0005634 nucleus", "go_biological_process": "GO:0042138 meiotic DNA double-strand break formation;GO:0007131 reciprocal meiotic recombination", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P21651-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P21672-1", "uniprot_id": "RIR3_YEAST", "mass": 97515.0, "length": 869, "protein_name": "Ribonucleoside-diphosphate reductase large chain 2", "gene_name": "RNR3", "organism": "Yeast", "refseq_name": "ribonucleotide-diphosphate reductase subunit RNR3", "refseq_ac": "NP_012198", "gene_names_uniprotkb": "RNR3; DIN1", "gene_names_refseq": "DIN1; RIR3; RNR3", "protein_names_uniprotkb": "Ribonucleoside-diphosphate reductase large chain 2; 1.17.4.1; Ribonucleotide reductase DNA damage-inducible regulatory subunit 2; Ribonucleotide reductase R1 subunit 2; Ribonucleotide reductase large subunit 2", "protein_names_refseq": "ribonucleotide-diphosphate reductase subunit RNR3", "tax_id": 559292, "disease": "chronic progressive external ophthalmoplegia (Disease Ontology:DOID:12558); lung non-small cell carcinoma (Disease Ontology:DOID:3908)", "pathway": " (sce:YIL066C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "11893751;12732713;14562106;17563356;18407956;20190278;2199320;2204819;23749301;24374639;33481703;33491328;9169870", "class_list": "", "function": "Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VVL8", "ec_number_list": "1.17.4.1", "go_molecular_function": "GO:0005524 ATP binding;GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005971 ribonucleoside-diphosphate reductase complex", "go_biological_process": "GO:0009263 deoxyribonucleotide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P21672-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P21691-1", "uniprot_id": "SIR1_YEAST", "mass": 76933.0, "length": 654, "protein_name": "Regulatory protein SIR1", "gene_name": "SIR1", "organism": "Yeast", "refseq_name": "Sir1p", "refseq_ac": "NP_013027", "gene_names_uniprotkb": "SIR1", "gene_names_refseq": "SIR1", "protein_names_uniprotkb": "Regulatory protein SIR1; Heterochromatin protein SIR1; Silent information regulator 1", "protein_names_refseq": "Sir1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YKR101W)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "11157772;11722841;12134062;12198162;12975325;14701749;15932939;15937111;19171939;2005909;24374639;8196765;8221892;8622770", "class_list": "", "function": "Involved in the establishment, but not the maintenance, of heterochromatic silencing at the cryptic mating-type loci HMR and HML. Is recruited by interacting with the ORC1 subunit of the origin recognition complex (ORC), which binds to HML-I or HMR-E silencers, DNA elements that direct the formation of silent chromatin at the mating-type loci. Establishes transcriptional silencing by recruiting the three other SIR proteins, SIR2, SIR3, and SIR4, that function directly in silenced chromatin and establish repression. Also found in centromeric chromatin. Binds to and helps retain CAC1, a subunit of chromatin assembly factor I (CAF-I) at centromeric loci independent on the other SIR proteins., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 22, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXG2", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000775 chromosome, centromeric region;GO:0005677 chromatin silencing complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0031507 heterochromatin formation;GO:0030466 silent mating-type cassette heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P21691-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P21734-1", "uniprot_id": "UBC1_YEAST", "mass": 24178.0, "length": 215, "protein_name": "Ubiquitin-conjugating enzyme E2 1", "gene_name": "UBC1", "organism": "Yeast", "refseq_name": "E2 ubiquitin-conjugating protein UBC1", "refseq_ac": "NP_010462", "gene_names_uniprotkb": "UBC1; YD9395.10", "gene_names_refseq": "UBC1", "protein_names_uniprotkb": "Ubiquitin-conjugating enzyme E2 1; 2.3.2.23; E2 ubiquitin-conjugating enzyme 1; Ubiquitin carrier protein; Ubiquitin-conjugating enzyme E2-24 kDa; Ubiquitin-protein ligase", "protein_names_refseq": "E2 ubiquitin-conjugating protein UBC1", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR177W); (R-SCE-983168)", "pathway_count": 2, "publication_count": 13, "publication_id_list": "10878801;11146622;11591345;14562106;15328341;17322287;21996927;22106047;2265617;24374639;33481703;33491328;9169867", "class_list": "", "function": "Catalyzes the covalent attachment of ubiquitin to other proteins. Functions in degradation of misfolded or regulated proteins localized in the endoplasmic reticulum (ER) lumen or membrane via the ubiquitin-proteasome system. Cognate E2 conjugating enzyme for the HRD1 ubiquitin ligase complex, which is part of the ERAD-L and ERAD-M pathways responsible for the rapid degradation of soluble lumenal and membrane proteins with misfolded lumenal domains (ERAD-L), or ER-membrane proteins with misfolded transmembrane domains (ERAD-M)., [UniProtKB, UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSF9", "ec_number_list": "2.3.2.23;2.3.2.27;6.2.1.45;2.3.2.-;2.3.2.26;2.3.2.31;1.14.11.27;2.3.2.34;6.3.2.-", "go_molecular_function": "GO:0005524 ATP binding;GO:0004842 ubiquitin-protein transferase activity;GO:0070628 proteasome binding;GO:0061631 ubiquitin conjugating enzyme activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0016050 vesicle organization;GO:0000209 protein polyubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0036503 ERAD pathway", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P21734-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P21801-1", "uniprot_id": "SDHB_YEAST", "mass": 30231.0, "length": 266, "protein_name": "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "gene_name": "SDH2", "organism": "Yeast", "refseq_name": "succinate dehydrogenase iron-sulfur protein subunit SDH2", "refseq_ac": "NP_013059", "gene_names_uniprotkb": "SDH2; SDHB; SDH", "gene_names_refseq": "ACN17; SDH2", "protein_names_uniprotkb": "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; 1.3.5.1; Ip; Iron-sulfur subunit of complex II", "protein_names_refseq": "succinate dehydrogenase iron-sulfur protein subunit SDH2", "tax_id": 559292, "disease": "pheochromocytoma (Disease Ontology:DOID:0050771); paraganglioma (Disease Ontology:DOID:0050773); mitochondrial complex II deficiency (Disease Ontology:DOID:0060537); pheochromocytoma/paraganglioma syndrome 4 (Disease Ontology:DOID:0061219); Carney-Stratakis syndrome (Disease Ontology:DOID:0080533); mitochondrial encephalomyopathy (Disease Ontology:DOID:890); gastrointestinal stromal tumor (Disease Ontology:DOID:9253); type 2 diabetes mellitus (Disease Ontology:DOID:9352); acute myocardial infarction (Disease Ontology:DOID:9408)", "pathway": " (sce:YLL041C); (R-SCE-71403)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "11803020;1390628;14562106;14672929;17322287;2191948;24374639;2494655;9169871", "class_list": "", "function": "Subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). SDH1 and SDH2 form the catalytic dimer. Electrons flow from succinate to the FAD bound to SDH1, and sequentially through the iron-sulfur clusters bound to SDH2 and enter the membrane dimer formed by SDH3 and SDH4., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXW5", "ec_number_list": "1.3.5.1", "go_molecular_function": "GO:0009055 electron transfer activity;GO:0046872 metal ion binding;GO:0051538 3 iron, 4 sulfur cluster binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0051537 2 iron, 2 sulfur cluster binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0031966 mitochondrial membrane;GO:0045273 respiratory chain complex II (succinate dehydrogenase)", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0022904 respiratory electron transport chain;GO:0009060 aerobic respiration;GO:0006121 mitochondrial electron transport, succinate to ubiquinone;GO:0045333 cellular respiration", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P21801-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P21825-1", "uniprot_id": "SEC62_YEAST", "mass": 31347.0, "length": 274, "protein_name": "Translocation protein SEC62", "gene_name": "SEC62", "organism": "Yeast", "refseq_name": "Sec63 complex subunit SEC62", "refseq_ac": "NP_015231", "gene_names_uniprotkb": "SEC62; LPG14C", "gene_names_refseq": "LPG14; SEC62", "protein_names_uniprotkb": "Translocation protein SEC62; Sec62/63 complex 30 kDa subunit", "protein_names_refseq": "Sec63 complex subunit SEC62", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL094C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "12518317;14562106;14617809;16847258;2000150;21126336;22814378;24374639;2687286;7758110;9169875", "class_list": "", "function": "Acts as a component of the Sec62/63 complex which is involved in SRP-independent post-translational translocation across the endoplasmic reticulum (ER) and functions together with the Sec61 complex and KAR2 in a channel-forming translocon complex. In an initial step, the signal sequence seems to bind simultaneously to SEC61 and SEC62. SEC62 and SEC63 are required for interactions between SEC61 and translocating polypeptides. SEC62 may affect SEC1-polypeptide interactions by increasing the affinity of targeting pathways for SEC61 and/or by modifying SEC61 to allow more efficient polypeptide interaction. A cycle of assembly and disassembly of Sec62/63 complex from SEC61 may govern the activity of the translocon. SEC62 is essential for cell growth., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3S3", "ec_number_list": "", "go_molecular_function": "GO:0008320 protein transmembrane transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0030867 rough endoplasmic reticulum membrane;GO:0031207 Sec62/Sec63 complex", "go_biological_process": "GO:0031204 post-translational protein targeting to membrane, translocation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P21825-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P21826-1", "uniprot_id": "MLS2_YEAST", "mass": 62794.0, "length": 554, "protein_name": "Malate synthase 2", "gene_name": "DAL7", "organism": "Yeast", "refseq_name": "malate synthase DAL7", "refseq_ac": "NP_012297", "gene_names_uniprotkb": "DAL7; MLS2", "gene_names_refseq": "DAL7; MLS2; MSL2", "protein_names_uniprotkb": "Malate synthase 2; 2.3.3.9; Degradation of allantoin protein 7", "protein_names_refseq": "malate synthase DAL7", "tax_id": 559292, "disease": "", "pathway": " (sce:YIR031C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "24374639;2552287;27678487;3915539;8462696;9169870", "class_list": "", "function": "Allantoin metabolism-specific malate synthase involved in the recycling the glyoxylate generated during allantoin degradation by the ureidoglycollate (UG) hydrolase reaction., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVW2", "ec_number_list": "2.3.3.9", "go_molecular_function": "GO:0004474 malate synthase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005777 peroxisome;GO:0005782 peroxisomal matrix;GO:0005829 cytosol", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0000256 allantoin catabolic process;GO:0006144 purine nucleobase metabolic process;GO:0006097 glyoxylate cycle", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P21826-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P21827-1", "uniprot_id": "RCC1_YEAST", "mass": 53014.0, "length": 482, "protein_name": "Guanine nucleotide exchange factor SRM1", "gene_name": "SRM1", "organism": "Yeast", "refseq_name": "Ran guanyl-nucleotide exchange factor", "refseq_ac": "NP_011418", "gene_names_uniprotkb": "SRM1; MTR1; PRP20", "gene_names_refseq": "MTR1; PRP20; SRM1; TSM437", "protein_names_uniprotkb": "Guanine nucleotide exchange factor SRM1; Pheromone response pathway component SRM1; Pre-mRNA-processing protein 20; Regulator of chromosome condensation; Suppressor of receptor mutations 1; mRNA transport protein 1", "protein_names_refseq": "Ran guanyl-nucleotide exchange factor", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL097W); (R-SCE-9615933)", "pathway_count": 2, "publication_count": 38, "publication_id_list": "11071906;11142374;11509570;11523802;11535617;11589573;12654904;1398069;14562106;16365162;1666302;17330950;17563356;18407956;1865879;19684113;19779198;19795423;19823750;2022190;20702584;21126336;21177495;2277633;23749301;24374639;2548085;30516470;33481703;33491328;7679070;8070652;8270631;8676864;9169869;9290212;9395535;9971735", "class_list": "", "function": "Guanine nucleotide exchange factor that promotes the exchange of GSP1/GSP2-bound GDP by GTP and controls RNA metabolism and transport. Involved in yeast pheromone response pathway and in mRNA metabolism. Involved in nuclear pore complex (NPC) assembly and required for mRNA and ribosome nuclear export. Binds chromatin and is involved NPC-mediated transcriptional control., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VU48", "ec_number_list": "", "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000785 chromatin", "go_biological_process": "GO:0016973 poly(A)+ mRNA export from nucleus;GO:0051301 cell division;GO:0007346 regulation of mitotic cell cycle;GO:0000054 ribosomal subunit export from nucleus;GO:0019236 response to pheromone", "synthesized_glycan_count": 0, "hit_score": 3.9, "record_id": "P21827-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P21954-1", "uniprot_id": "IDHP_YEAST", "mass": 48190.0, "length": 428, "protein_name": "Isocitrate dehydrogenase [NADP], mitochondrial", "gene_name": "IDP1", "organism": "Yeast", "refseq_name": "isocitrate dehydrogenase (NADP(+)) IDP1", "refseq_ac": "NP_010217", "gene_names_uniprotkb": "IDP1", "gene_names_refseq": "IDP1", "protein_names_uniprotkb": "Isocitrate dehydrogenase [NADP], mitochondrial; 1.1.1.42; IDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase", "protein_names_refseq": "isocitrate dehydrogenase (NADP(+)) IDP1", "tax_id": 559292, "disease": "D-2-hydroxyglutaric aciduria (Disease Ontology:DOID:0050575); myelodysplastic syndrome (Disease Ontology:DOID:0050908); cancer (Disease Ontology:DOID:162); glioblastoma (Disease Ontology:DOID:3068); high grade glioma (Disease Ontology:DOID:3070); lung squamous cell carcinoma (Disease Ontology:DOID:3907); lung adenocarcinoma (Disease Ontology:DOID:3910); autoimmune disease (Disease Ontology:DOID:417); hepatocellular clear cell carcinoma (Disease Ontology:DOID:5016); acute myeloid leukemia (Disease Ontology:DOID:9119)", "pathway": " (sce:YDL066W); (R-SCE-389542); (R-SCE-6798695); (R-SCE-9033241)", "pathway_count": 4, "publication_count": 4, "publication_id_list": "1989987;24374639;33491328;9169867", "class_list": "", "function": "Mitochondrial IDP1 may regulate flux through the tricarboxylic acid cycle and respiration. Its probably critical function is the production of NADPH., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRT1", "ec_number_list": "2.7.1.40;5.4.2.11;2.7.1.1;4.2.1.24;3.6.4.13;2.4.1.1;3.4.23.25;3.6.4.10;5.3.1.9;5.1.3.-;5.2.1.8;1.11.1.6;3.5.4.6;1.6.2.4;2.7.1.11;2.7.1.2;1.1.1.42;3.4.25.1;3.6.4.6;3.6.5.-;2.7.11.24;1.3.1.124;2.3.1.7;3.6.4.12;5.4.2.2;1.11.1.24;2.7.4.6;2.4.1.186;1.1.1.205;2.7.1.35;4.1.2.63;3.1.2.2;3.4.19.12;2.4.2.7;3.5.1.3;5.4.2.7;2.3.2.26;2.7.11.23;2.3.2.27;2.4.2.1;5.3.3.8;3.4.24.-;2.7.1.59;3.2.1.14;3.5.4.5;3.4.11.-;3.3.2.10;3.6.1.-;3.6.1.56;3.6.1.77", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0051287 NAD binding;GO:0004450 isocitrate dehydrogenase (NADP+) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005777 peroxisome;GO:0042645 mitochondrial nucleoid", "go_biological_process": "GO:0006739 NADP+ metabolic process;GO:0006099 tricarboxylic acid cycle;GO:0006102 isocitrate metabolic process;GO:0006537 glutamate biosynthetic process;GO:0006097 glyoxylate cycle", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P21954-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P21957-1", "uniprot_id": "OPI1_YEAST", "mass": 46065.0, "length": 404, "protein_name": "Transcriptional repressor OPI1", "gene_name": "OPI1", "organism": "Yeast", "refseq_name": "transcriptional regulator OPI1", "refseq_ac": "NP_011843", "gene_names_uniprotkb": "OPI1", "gene_names_refseq": "OPI1", "protein_names_uniprotkb": "Transcriptional repressor OPI1; Negative regulator of phospholipid biosynthesis; Overproducer of inositol protein 1", "protein_names_refseq": "transcriptional regulator OPI1", "tax_id": 559292, "disease": "", "pathway": " (sce:YHL020C)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "11395523;12668681;12727870;14562095;14562106;15192221;15455074;16407309;17322287;17330950;17563356;18407956;19779198;19795423;19823750;1985968;21900497;23749301;24374639;27743455;33481703;33491328;8091229", "class_list": "", "function": "Negative regulator of the transcriptional complex INO2-INO4 in response to phospholipid precursor availability. When precursors become limiting, OPI1 is retained at the endoplasmic reticulum (ER) and INO2-INO4 activates INO1 and other genes required for phospholipid biosynthesis, whereas abundant precursor availability results in targeting of OPI1 to the nucleus to repress transcription of these genes. Binds directly to phosphatidic acid, which is required for ER targeting and may act as sensing mechanism for precursor availability, as phosphatidic acid becomes rapidly depleted upon phospholipid biosynthesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 22, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DKP9", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003714 transcription corepressor activity;GO:0070300 phosphatidic acid binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005654 nucleoplasm;GO:0005783 endoplasmic reticulum;GO:0031965 nuclear membrane", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0030968 endoplasmic reticulum unfolded protein response", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P21957-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P21965-1", "uniprot_id": "MCK1_YEAST", "mass": 43136.0, "length": 375, "protein_name": "Protein kinase MCK1", "gene_name": "MCK1", "organism": "Yeast", "refseq_name": "serine/threonine/tyrosine protein kinase MCK1", "refseq_ac": "NP_014092", "gene_names_uniprotkb": "MCK1; N0392; YPK1", "gene_names_refseq": "CMS1; MCK1; YPK1", "protein_names_uniprotkb": "Protein kinase MCK1; 2.7.12.1; Meiosis and centromere regulatory kinase", "protein_names_refseq": "serine/threonine/tyrosine protein kinase MCK1", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL307C); (R-SCE-3371453); (R-SCE-69601); (R-SCE-9856649)", "pathway_count": 4, "publication_count": 26, "publication_id_list": "11877433;14562106;1701015;17330950;17563356;18407956;19684113;19779198;19795423;19823750;2010083;2010084;20489023;20702584;21126336;21177495;22218487;22814378;23749301;24374639;32597660;33481703;33491328;7502583;8553702;9169873", "class_list": "", "function": "May be an autophosphorylating tyrosine kinase, a bifunctional (serine/tyrosine-specific) protein kinase, or a serine kinase that is a substrate for an associated tyrosine kinase. MCK1 is a transcriptional activator of IME1, it stimulates spore maturation, and play a positive regulatory role in both mitotic centromere function and activation of early meiotic gene expression., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0N8", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;3.1.3.48;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0004857 enzyme inhibitor activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0015629 actin cytoskeleton", "go_biological_process": "GO:0007165 signal transduction;GO:0030154 cell differentiation;GO:0006303 double-strand break repair via nonhomologous end joining;GO:0030163 protein catabolic process;GO:0051321 meiotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 2.7, "record_id": "P21965-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22007-1", "uniprot_id": "FNTB_YEAST", "mass": 48190.0, "length": 431, "protein_name": "Protein farnesyltransferase subunit beta", "gene_name": "RAM1", "organism": "Yeast", "refseq_name": "protein farnesyltransferase", "refseq_ac": "NP_010193", "gene_names_uniprotkb": "RAM1; D2412; DPR1; SCG2; STE16", "gene_names_refseq": "DPR1; FUS8; RAM1; SCG2; SGP2; STE16", "protein_names_uniprotkb": "Protein farnesyltransferase subunit beta; 2.5.1.58; CAAX farnesyltransferase subunit beta; FTase-beta; PFTase beta; Ras proteins prenyltransferase subunit beta", "protein_names_refseq": "protein farnesyltransferase", "tax_id": 559292, "disease": "anxiety disorder (Disease Ontology:DOID:2030)", "pathway": " (sce:YDL090C); (R-SCE-9648002)", "pathway_count": 2, "publication_count": 26, "publication_id_list": "10529185;12173942;12667062;14562095;14562106;17142567;17322287;1763050;18407956;1860864;2124698;24374639;3064491;33491328;3533274;7651159;7878044;8424764;8494894;8527442;8923743;8995312;9169867;9174352;9380709;9545274", "class_list": "", "function": "Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X where X is Ser, Ala, Met, Cys, or Gln. Required for the membrane localization of proteins such as a-factor, Ras proteins and other membrane proteins containing the C-terminal CAAX motif (PubMed:17142567, PubMed:1763050, PubMed:1860864, PubMed:2124698, PubMed:3533274, PubMed:8424764, PubMed:8527442). The beta subunit is responsible for isoprenoid and peptide-binding (PubMed:12667062, PubMed:7878044, PubMed:8995312, PubMed:9380709, PubMed:9545274)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 19, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRQ8;E9P902;Q12422", "ec_number_list": "2.5.1.58;2.5.1.59", "go_molecular_function": "GO:0004660 protein farnesyltransferase activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005965 protein farnesyltransferase complex", "go_biological_process": "GO:0018343 protein farnesylation;GO:0051604 protein maturation", "synthesized_glycan_count": 0, "hit_score": 2.7, "record_id": "P22007-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22108-1", "uniprot_id": "APA2_YEAST", "mass": 36841.0, "length": 325, "protein_name": "Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase 2", "gene_name": "APA2", "organism": "Yeast", "refseq_name": "bifunctional AP-4-A phosphorylase/ADP sulfurylase", "refseq_ac": "NP_010819", "gene_names_uniprotkb": "APA2; D9719.33", "gene_names_refseq": "APA2", "protein_names_uniprotkb": "Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase 2; 2.7.7.53; 2.7.7.5; ADP-sulfurylase; ATP adenylyltransferase; Ap4A phosphorylase 2", "protein_names_refseq": "bifunctional AP-4-A phosphorylase/ADP sulfurylase", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR530C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562095;14562106;2174863;23628156;24374639;2556364;2982863;9169867", "class_list": "", "function": "Ap4A phosphorylase catalyzes the phosphorolytic degradation of bis(5'-adenosyl) tetraphosphate (Ap4A) into ADP and ATP. Can also use other Np4N' nucleotides (where N and N' stand for A,C,G or U) as substrates, but prefers A-containing substrates. Cannot catalyze the reverse reaction. Additionally, this enzyme can also catalyze the phosphorolytic degradation of adenosine 5'-phosphosulfate (AMPS) into ADP and sulfate, the reversible exchange reaction between inorganic phosphate and the beta-phosphate of a nucleoside diphosphate (NDP), and the synthesis of Ap4A from AMPS plus ATP., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTF1", "ec_number_list": "2.7.7.5;2.7.7.53", "go_molecular_function": "GO:0005524 ATP binding;GO:0003877 ATP:ADP adenylyltransferase activity;GO:0008796 bis(5'-nucleosyl)-tetraphosphatase activity;GO:0004780 sulfate adenylyltransferase (ADP) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0009165 nucleotide biosynthetic process;GO:0009164 nucleoside catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P22108-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22133-1", "uniprot_id": "MDHC_YEAST", "mass": 40731.0, "length": 377, "protein_name": "Malate dehydrogenase, cytoplasmic", "gene_name": "MDH2", "organism": "Yeast", "refseq_name": "malate dehydrogenase MDH2", "refseq_ac": "NP_014515", "gene_names_uniprotkb": "MDH2", "gene_names_refseq": "MDH2", "protein_names_uniprotkb": "Malate dehydrogenase, cytoplasmic; 1.1.1.37", "protein_names_refseq": "malate dehydrogenase MDH2", "tax_id": 559292, "disease": "developmental and epileptic encephalopathy 51 (Disease Ontology:DOID:0080433); brain ischemia (Disease Ontology:DOID:2316); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000)", "pathway": " (sce:YOL126C); (R-SCE-71403); (R-SCE-9837999); (R-SCE-9856872)", "pathway_count": 4, "publication_count": 10, "publication_id_list": "14562106;18407956;1986231;24374639;28126757;32597660;33491328;3552052;8896265;9169874", "class_list": "", "function": "The isoenzyme MDH2 may function primarily in the glyoxylate cycle., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W1U2", "ec_number_list": "3.5.3.1;7.1.2.2;2.3.3.1;4.2.1.2;3.6.4.10;4.98.1.1;1.1.1.37;4.2.1.3;1.2.4.2;1.2.4.1;3.4.21.53;2.3.1.41;1.2.1.4;1.2.1.5;6.1.1.5;2.3.3.10", "go_molecular_function": "GO:0030060 L-malate dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0034399 nuclear periphery", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0006094 gluconeogenesis;GO:0016558 protein import into peroxisome matrix;GO:0006108 malate metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P22133-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22134-1", "uniprot_id": "MAG_YEAST", "mass": 34333.0, "length": 296, "protein_name": "DNA-3-methyladenine glycosylase", "gene_name": "MAG1", "organism": "Yeast", "refseq_name": "DNA-3-methyladenine glycosylase II", "refseq_ac": "NP_011069", "gene_names_uniprotkb": "MAG1; MAG", "gene_names_refseq": "MAG1; MMS5", "protein_names_uniprotkb": "DNA-3-methyladenine glycosylase; 3-methyladenine DNA glycosidase; 3.2.2.21; 3MEA DNA glycosylase", "protein_names_refseq": "DNA-3-methyladenine glycosylase II", "tax_id": 559292, "disease": "", "pathway": " (sce:YER142C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "11502169;17322287;18407956;2265619;2265620;24374639;33491328;7718559;9169868", "class_list": "", "function": "Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine or 7-methyladenine from the damaged DNA polymer formed by alkylation lesions., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DM49", "ec_number_list": "", "go_molecular_function": "GO:0003684 damaged DNA binding;GO:0003905 alkylbase DNA N-glycosylase activity;GO:0008725 DNA-3-methyladenine glycosylase activity;GO:0043916 DNA-7-methylguanine glycosylase activity;GO:0032131 alkylated DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006307 DNA alkylation repair;GO:0006285 base-excision repair, AP site formation", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P22134-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22137-1", "uniprot_id": "CLH_YEAST", "mass": 187234.0, "length": 1653, "protein_name": "Clathrin heavy chain", "gene_name": "CHC1", "organism": "Yeast", "refseq_name": "clathrin heavy chain", "refseq_ac": "NP_011309", "gene_names_uniprotkb": "CHC1", "gene_names_refseq": "CHC1; SWA5", "protein_names_uniprotkb": "Clathrin heavy chain", "protein_names_refseq": "clathrin heavy chain", "tax_id": 559292, "disease": "autosomal dominant intellectual developmental disorder 56 (Disease Ontology:DOID:0080226)", "pathway": " (sce:YGL206C); (R-SCE-190873); (R-SCE-196025); (R-SCE-432720); (R-SCE-437239); (R-SCE-8856828); (R-SCE-8866427); (R-SCE-8964038); (R-SCE-9013420); (R-SCE-9013424)", "pathway_count": 10, "publication_count": 11, "publication_id_list": "12686590;14562106;16687570;18407956;1898742;22106047;24374639;33481703;33491328;9153757;9169869", "class_list": "", "function": "Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. In yeast, it is involved in the retention of proteins in an intracellular membrane compartment, presumably the trans-Golgi., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTU9", "ec_number_list": "", "go_molecular_function": "GO:0005198 structural molecule activity;GO:0032051 clathrin light chain binding", "go_cellular_component": "GO:0030125 clathrin vesicle coat;GO:0005829 cytosol;GO:0030130 clathrin coat of trans-Golgi network vesicle;GO:0030479 actin cortical patch;GO:0071439 clathrin complex", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006897 endocytosis;GO:0006898 receptor-mediated endocytosis;GO:0030866 cortical actin cytoskeleton organization;GO:0048268 clathrin coat assembly", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P22137-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22140-1", "uniprot_id": "EPT1_YEAST", "mass": 44560.0, "length": 391, "protein_name": "Choline/ethanolaminephosphotransferase 1", "gene_name": "EPT1", "organism": "Yeast", "refseq_name": "bifunctional diacylglycerol cholinephosphotransferase/ethanolaminephosphotransferase", "refseq_ac": "NP_011991", "gene_names_uniprotkb": "EPT1", "gene_names_refseq": "EPT1", "protein_names_uniprotkb": "Choline/ethanolaminephosphotransferase 1; 2.7.8.1; 2.7.8.2; Aminoalcohol phosphotransferase EPT1; ETHPT; Ethanolaminephosphotransferase 1", "protein_names_refseq": "bifunctional diacylglycerol cholinephosphotransferase/ethanolaminephosphotransferase", "tax_id": 559292, "disease": "hereditary spastic paraplegia 81 (Disease Ontology:DOID:0112349)", "pathway": " (sce:YHR123W); (R-SCE-1483191); (R-SCE-1483213)", "pathway_count": 3, "publication_count": 9, "publication_id_list": "15225629;1847919;1848238;24374639;2848840;7961445;7961735;7961831;8091229", "class_list": "", "function": "Catalyzes the final step in the CDP-ethanolamine route leading to phosphatidylethanolamine (PE). Can also catalyze the formation of phosphatidylcholine (PC) from CDP-choline, but does not substantially contribute to PC biosynthesis. Preferentially uses CDP-dimethylethanolamine and CDP-propanolamine as aminoalcohol substrates. Shows highest activity toward di-unsaturated diacylglycerol species as lipid substrates. The CDP-ethanolamine pathway may play a role in maintaining the proper PE species distribution., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DL73", "ec_number_list": "2.7.8.2;2.7.8.1", "go_molecular_function": "GO:0004142 diacylglycerol cholinephosphotransferase activity;GO:0004307 ethanolaminephosphotransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0006656 phosphatidylcholine biosynthetic process;GO:0006646 phosphatidylethanolamine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P22140-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22141-1", "uniprot_id": "PSB4_YEAST", "mass": 22517.0, "length": 198, "protein_name": "Proteasome subunit beta type-4", "gene_name": "PRE1", "organism": "Yeast", "refseq_name": "proteasome core particle subunit beta 4", "refseq_ac": "NP_010928", "gene_names_uniprotkb": "PRE1", "gene_names_refseq": "PRE1", "protein_names_uniprotkb": "Proteasome subunit beta type-4; Macropain subunit C11; Multicatalytic endopeptidase complex subunit C11; Proteasome component C11; Proteinase YSCE subunit 11", "protein_names_refseq": "proteasome core particle subunit beta 4", "tax_id": 559292, "disease": "", "pathway": " (sce:YER012W); (R-SCE-1236978); (R-SCE-5668541); (R-SCE-5689880); (R-SCE-9907900); (R-SCE-9912633)", "pathway_count": 6, "publication_count": 18, "publication_id_list": "11062564;11081519;14562106;16531229;16608349;16793518;17322287;18407956;2001673;20227375;20486117;22814378;22927375;24374639;30516470;33491328;9087403;9169868", "class_list": "", "function": "Non-catalytic component of the proteasome which degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity. This subunit has a chymotrypsin-like activity., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D3DLQ9", "ec_number_list": "", "go_molecular_function": "GO:0061133 endopeptidase activator activity", "go_cellular_component": "GO:0019774 proteasome core complex, beta-subunit complex;GO:0005634 nucleus;GO:0005829 cytosol;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0010499 proteasomal ubiquitin-independent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P22141-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22147-1", "uniprot_id": "XRN1_YEAST", "mass": 175460.0, "length": 1528, "protein_name": "5'-3' exoribonuclease 1", "gene_name": "XRN1", "organism": "Yeast", "refseq_name": "chromatin-binding exonuclease XRN1", "refseq_ac": "NP_011342", "gene_names_uniprotkb": "XRN1; DST2; G1645; KEM1; RAR5; SEP1; SKI1", "gene_names_refseq": "DST2; KEM1; RAR5; SEP1; SKI1; XRN1", "protein_names_uniprotkb": "5'-3' exoribonuclease 1; 3.1.13.-; DNA strand transfer protein beta; KAR(-)-enhancing mutation protein; STP-beta; Strand exchange protein 1; p175", "protein_names_refseq": "chromatin-binding exonuclease XRN1", "tax_id": 559292, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652)", "pathway": " (sce:YGL173C); (R-SCE-450385); (R-SCE-450513)", "pathway_count": 3, "publication_count": 75, "publication_id_list": "10454540;11142370;11238889;11910109;12423748;12730603;12799443;12853617;1398123;14561886;14562106;14690598;14729943;15013450;15358132;15665377;15967792;15989963;16240118;16352596;16373495;16501073;16714281;16885161;17151231;17287358;17330950;17429074;17563356;17761681;18162578;1840632;18407956;18443146;18469165;1850100;1856231;18640978;18676807;18689878;18715869;19324962;19684113;19779198;1979303;19795423;19823750;2027746;20702584;2076815;21177495;23749301;24374639;30377154;30516470;32597660;33229814;33481703;33491328;7597069;7713413;7720696;7739553;7926736;8020096;8106411;8106412;8188690;8619317;9169869;9315672;9482746;9488433;9685486;9742129", "class_list": "", "function": "Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. The NMD pathway has a second role regulating the decay of wild-type mRNAs, and especially mRNAs that are important for telomere functions. Participate in CTH2-mediated and VTS1-mediated mRNA turnover. Involved in the degradation of several hypomodified mature tRNA species and participates in the 5'-processing or the degradation of the snoRNA precursors and rRNA processing. Involved in defense against virus and suppresses viral RNA recombination by rapidly removing the 5'-truncated RNAs, the substrates of recombination, and thus reducing the chance for recombination to occur in the parental strain. Required for the assembly of the virus-like particles of the Ty3 retrotransposon and contributes to the efficient generation of narnavirus 20S RNA by playing a major role in the elimination of the non-viral upstream sequences from the primary transcripts. Degrades single-stranded DNA (ss-DNA) and can renature complementary ss-DNA as well as catalyzes the formation of heteroduplex DNA from circular ss-DNA and homologous linear ds-DNA in vitro. Acts as a microtubule-associated protein which interacts with cytoplasmic microtubules through beta-tubulin and promotes in vitro assembly of tubulin into microtubules. Associates with microtubule functions such as chromosome transmission, nuclear migration, and SPB duplication. Has also a role in G1 to S transition and is involved in nuclear fusion during karyogamy. Required for the expression of ROK1 at the post-transcriptional level and for the alpha-factor induction of the karyogamy genes KAR3 and KAR4. Plays a role in filamentous growth., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 26, "reported_mutagensis": 22, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VTX9", "ec_number_list": "3.1.13.-;3.6.1.62;3.1.26.-", "go_molecular_function": "GO:0003682 chromatin binding;GO:0003723 RNA binding;GO:0003729 mRNA binding;GO:0004534 5'-3' RNA exonuclease activity;GO:0031370 eukaryotic initiation factor 4G binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005874 microtubule;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0016078 tRNA decay;GO:0032204 regulation of telomere maintenance;GO:0070651 nonfunctional rRNA decay;GO:0006413 translational initiation", "synthesized_glycan_count": 0, "hit_score": 7.9, "record_id": "P22147-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22149-1", "uniprot_id": "AFT1_YEAST", "mass": 77683.0, "length": 690, "protein_name": "Iron-regulated transcriptional activator AFT1", "gene_name": "AFT1", "organism": "Yeast", "refseq_name": "DNA-binding transcription factor AFT1", "refseq_ac": "NP_011444", "gene_names_uniprotkb": "AFT1; RCS1", "gene_names_refseq": "AFT1; RCS1", "protein_names_uniprotkb": "Iron-regulated transcriptional activator AFT1; Activator of iron transcription protein 1", "protein_names_refseq": "DNA-binding transcription factor AFT1", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL071W)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "14562106;17322287;17538022;18407956;19779198;2021081;24374639;26450372;29032057;32597660;33481703;33491328;7720713;9169869;9200812;9290212", "class_list": "", "function": "Transcription factor that activates the genes for FRE1, FRE2 and FET3 in response to iron deprivationand thereby plays a central role in iron homeostasis (PubMed:7720713, PubMed:9200812). Also required for the expression of LSO1 (PubMed:26450372). Recognizes the consensus iron-responsive element (Fe-RE) sequence 5'-CACCC-3' in the promoters of target genes (By similarity). Iron could interact directly with AFT1 and inhibits its activity (PubMed:7720713). In high iron condition, the presence of Fe(2+) or [2Fe-2S] cluster leads to dimerization, which in turn leads to a decrease in DNA affinity (By similarity)., [UniProtKB, PubMed, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VU71;Q06993", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987 cis-regulatory region sequence-specific DNA binding;GO:0043515 kinetochore binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0007059 chromosome segregation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045132 meiotic chromosome segregation", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P22149-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22203-1", "uniprot_id": "VATE_YEAST", "mass": 26471.0, "length": 233, "protein_name": "V-type proton ATPase subunit E", "gene_name": "VMA4", "organism": "Yeast", "refseq_name": "H(+)-transporting V1 sector ATPase subunit E", "refseq_ac": "NP_014977", "gene_names_uniprotkb": "VMA4; O6241; VAT5", "gene_names_refseq": "VMA4", "protein_names_uniprotkb": "V-type proton ATPase subunit E; V-ATPase 27 kDa subunit; V-ATPase subunit E; Vacuolar proton pump subunit E", "protein_names_refseq": "H(+)-transporting V1 sector ATPase subunit E", "tax_id": 559292, "disease": "autosomal recessive cutis laxa type IIC (Disease Ontology:DOID:0070140)", "pathway": " (sce:YOR332W); (R-SCE-1222556); (R-SCE-77387); (R-SCE-917977); (R-SCE-9639288)", "pathway_count": 5, "publication_count": 25, "publication_id_list": "11283612;14562095;14562106;15718227;15751969;18055462;18407956;19779198;19795423;19823750;21126336;2145285;22218487;22814378;23749301;24374639;25971514;27295975;33481703;33491328;8416931;8626613;8896263;9169874;9660816", "class_list": "", "function": "Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:8416931). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (PubMed:2145285, PubMed:8416931)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 9, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W328", "ec_number_list": "", "go_molecular_function": "GO:0046961 proton-transporting ATPase activity, rotational mechanism", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0045121 membrane raft;GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0048388 endosomal lumen acidification;GO:0007035 vacuolar acidification;GO:1902600 proton transmembrane transport;GO:0061795 Golgi lumen acidification", "synthesized_glycan_count": 0, "hit_score": 2.6, "record_id": "P22203-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22204-1", "uniprot_id": "DBF2_YEAST", "mass": 66148.0, "length": 572, "protein_name": "Cell cycle protein kinase DBF2", "gene_name": "DBF2", "organism": "Yeast", "refseq_name": "serine/threonine-protein kinase DBF2", "refseq_ac": "NP_011606", "gene_names_uniprotkb": "DBF2", "gene_names_refseq": "DBF2", "protein_names_uniprotkb": "Cell cycle protein kinase DBF2; 2.7.11.1; Dumbbell forming protein 2", "protein_names_refseq": "serine/threonine-protein kinase DBF2", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR092W)", "pathway_count": 1, "publication_count": 36, "publication_id_list": "10228157;10984431;11378390;11404483;11434459;11598184;12832486;12937277;14551257;14562106;15665377;16176976;16242037;17563356;18048916;18407956;1916278;19221193;19779198;20123997;20442249;20489023;20702584;2181271;22196726;22573892;23447700;23749301;24374639;32597660;33481703;33491328;8131744;9169869;9528782;9613578", "class_list": "", "function": "Ser/Thr-protein kinase involved in the mitotic exit network (MEN) and required after the metaphase to anaphase cell cycle transition. Phosphorylates CHS2 to regulate its dynamics and chitin synthesis at the division site during cytokinesis. Coordinates septin and actomyosin ring (AMR) functions during cytokinesis through the phosphorylation of HOF1. In complex with MOB1, phosphorylates CDC14 at sites adjacent to its nuclear localization sequence, thereby retaining CDC14 in the cytoplasm. Also binds to SWI5 and CLB2 mRNAs cotranscriptionally to regulate their decay. In the nucleus, the DBF2-MOB1 complex regulates passenger protein localization during anaphase. Mediates sorbic acid stress tolerance through promoting vacuolar H(+)-ATPase function, probably through phosphorylation of VMA1 and VMA2 subunits., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 29, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUM4", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0003723 RNA binding;GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005816 spindle pole body;GO:0034973 Sid2-Mob1 complex;GO:0005935 cellular bud neck", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0010458 exit from mitosis;GO:0007096 regulation of exit from mitosis;GO:0032465 regulation of cytokinesis;GO:0007035 vacuolar acidification", "synthesized_glycan_count": 0, "hit_score": 3.7, "record_id": "P22204-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22213-1", "uniprot_id": "SLY1_YEAST", "mass": 74679.0, "length": 666, "protein_name": "Protein SLY1", "gene_name": "SLY1", "organism": "Yeast", "refseq_name": "syntaxin-binding protein", "refseq_ac": "NP_010475", "gene_names_uniprotkb": "SLY1; YD9346.01; YD9395.22", "gene_names_refseq": "SLY1", "protein_names_uniprotkb": "Protein SLY1; Suppressor of loss of YPT1 protein 1", "protein_names_refseq": "syntaxin-binding protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR189W); (R-SCE-204005); (R-SCE-8980692)", "pathway_count": 3, "publication_count": 9, "publication_id_list": "12426383;14562106;1990290;22814378;24374639;32597660;33481703;33491328;9169867", "class_list": "", "function": "Able to suppress the functional loss of YPT1. SLY1 is essential for cell viability. May interact indirectly, or directly with YPT1., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSH2", "ec_number_list": "", "go_molecular_function": "GO:0019905 syntaxin binding;GO:0000149 SNARE binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0046578 regulation of Ras protein signal transduction;GO:0048280 vesicle fusion with Golgi apparatus", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P22213-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22216-1", "uniprot_id": "RAD53_YEAST", "mass": 91962.0, "length": 821, "protein_name": "Serine/threonine-protein kinase RAD53", "gene_name": "RAD53", "organism": "Yeast", "refseq_name": "serine/threonine/tyrosine protein kinase RAD53", "refseq_ac": "NP_015172", "gene_names_uniprotkb": "RAD53; MEC2; P2588; SAD1; SPK1", "gene_names_refseq": "LSD1; MEC2; RAD53; SPK1", "protein_names_uniprotkb": "Serine/threonine-protein kinase RAD53; 2.7.12.1; CHEK2 homolog; Serine-protein kinase 1", "protein_names_refseq": "serine/threonine/tyrosine protein kinase RAD53", "tax_id": 559292, "disease": "breast cancer (Disease Ontology:DOID:1612)", "pathway": " (sce:YPL153C); (R-SCE-5693565); (R-SCE-69473); (R-SCE-69601); (R-SCE-75035)", "pathway_count": 5, "publication_count": 35, "publication_id_list": "10550056;10562568;10588905;11106755;11124038;11809875;12667463;14562106;15024067;15972895;16085488;17114794;17287358;17322287;17563356;18407956;1899289;19779198;19801655;20046099;20190278;20489023;21126336;22323608;22814378;23749301;24302356;24374639;32597660;33481703;33491328;7958905;8355715;8948103;9169875", "class_list": "", "function": "Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5. Seems to be involved in the phosphorylation of RPH1., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 67, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3L5;Q6B1S1", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;3.1.3.48;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0003688 DNA replication origin binding;GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0043247 telomere maintenance in response to DNA damage;GO:0044773 mitotic DNA damage checkpoint signaling;GO:0006281 DNA repair;GO:0008104 intracellular protein localization;GO:0042326 negative regulation of phosphorylation", "synthesized_glycan_count": 0, "hit_score": 3.6, "record_id": "P22216-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22217-1", "uniprot_id": "TRX1_YEAST", "mass": 11235.0, "length": 103, "protein_name": "Thioredoxin-1", "gene_name": "TRX1", "organism": "Yeast", "refseq_name": "thioredoxin TRX1", "refseq_ac": "NP_013144", "gene_names_uniprotkb": "TRX1; TRX2", "gene_names_refseq": "LMA1; TRX1", "protein_names_uniprotkb": "Thioredoxin-1; TR-I; Thioredoxin I; Thioredoxin-2", "protein_names_refseq": "thioredoxin TRX1", "tax_id": 559292, "disease": "dilated cardiomyopathy (Disease Ontology:DOID:12930); glaucoma (Disease Ontology:DOID:1686); myocardial infarction (Disease Ontology:DOID:5844); myocarditis (Disease Ontology:DOID:820); intermediate coronary syndrome (Disease Ontology:DOID:8805); steatotic liver disease (Disease Ontology:DOID:9452)", "pathway": " (sce:YLR043C)", "pathway_count": 1, "publication_count": 30, "publication_id_list": "10681558;11018134;11169096;12410842;12437921;12914955;14562095;14562106;1561834;17322287;17932921;18407956;19362171;19779198;1988444;2026619;22106047;22984289;23749301;24374639;3060034;33481703;33491328;4945270;7961686;8603912;9015301;9169871;9657146;9988687", "class_list": "", "function": "Participates as a hydrogen donor in redox reactions through the reversible oxidation of its active center dithiol to a disulfide, accompanied by the transfer of 2 electrons and 2 protons. It is involved in many cellular processes, including deoxyribonucleotide synthesis, repair of oxidatively damaged proteins, protein folding, sulfur metabolism, and redox homeostasis. Thioredoxin-dependent enzymes include phosphoadenosine-phosphosulfate reductase MET16, alkyl-hydroperoxide reductase DOT5, thioredoxin peroxidases TSA1 and TSA2, alkyl hydroperoxide reductase AHP1, and peroxiredoxin HYR1. Thioredoxin is also involved in protection against reducing stress. As part of the LMA1 complex, it is involved in the facilitation of vesicle fusion such as homotypic vacuole and ER-derived COPII vesicle fusion with the Golgi. This activity does not require the redox mechanism., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VY45", "ec_number_list": "", "go_molecular_function": "GO:0015036 disulfide oxidoreductase activity;GO:0015035 protein-disulfide reductase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005758 mitochondrial intermembrane space", "go_biological_process": "GO:0080058 protein deglutathionylation;GO:0042144 vacuole fusion, non-autophagic;GO:0015031 protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0045454 cell redox homeostasis", "synthesized_glycan_count": 0, "hit_score": 3.1, "record_id": "P22217-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22224-1", "uniprot_id": "SEC15_YEAST", "mass": 105064.0, "length": 910, "protein_name": "Exocyst complex component SEC15", "gene_name": "SEC15", "organism": "Yeast", "refseq_name": "Rab GTPase-binding exocyst subunit SEC15", "refseq_ac": "NP_011281", "gene_names_uniprotkb": "SEC15", "gene_names_refseq": "SEC15", "protein_names_uniprotkb": "Exocyst complex component SEC15", "protein_names_refseq": "Rab GTPase-binding exocyst subunit SEC15", "tax_id": 559292, "disease": "spondyloepimetaphyseal dysplasia with joint laxity type 3 (Disease Ontology:DOID:0112200)", "pathway": " (sce:YGL233W); (R-SCE-264876)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "14562106;1512289;18407956;19779198;24374639;2504727;33491328;9169869", "class_list": "", "function": "Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VVA1", "ec_number_list": "", "go_molecular_function": "GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0000145 exocyst;GO:0000131 incipient cellular bud site;GO:0005628 prospore membrane;GO:0005934 cellular bud tip", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006887 exocytosis;GO:0006893 Golgi to plasma membrane transport;GO:0006904 vesicle docking involved in exocytosis;GO:0090522 vesicle tethering involved in exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P22224-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22276-1", "uniprot_id": "RPC2_YEAST", "mass": 129456.0, "length": 1149, "protein_name": "DNA-directed RNA polymerase III subunit RPC2", "gene_name": "RET1", "organism": "Yeast", "refseq_name": "DNA-directed RNA polymerase III core subunit RET1", "refseq_ac": "NP_014850", "gene_names_uniprotkb": "RET1; RPC128; RPC2", "gene_names_refseq": "PDS2; RET1; RPC128; RPC2", "protein_names_uniprotkb": "DNA-directed RNA polymerase III subunit RPC2; 2.7.7.6; C128; DNA-directed RNA polymerase III 130 kDa polypeptide; RNA polymerase III subunit C2", "protein_names_refseq": "DNA-directed RNA polymerase III core subunit RET1", "tax_id": 559292, "disease": "hypomyelinating leukodystrophy (Disease Ontology:DOID:0060786); hypomyelinating leukodystrophy 8 (Disease Ontology:DOID:0060797); Charcot-Marie-Tooth disease (Disease Ontology:DOID:10595)", "pathway": " (sce:YOR207C); (R-SCE-76061); (R-SCE-76066)", "pathway_count": 3, "publication_count": 9, "publication_id_list": "10384303;14562095;14562106;16818233;2005101;21177495;24374639;33491328;9169874", "class_list": "", "function": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2R3;Q12696", "ec_number_list": "2.7.7.6", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0032549 ribonucleoside binding;GO:0003899 DNA-directed RNA polymerase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005666 RNA polymerase III complex", "go_biological_process": "GO:0042797 tRNA transcription by RNA polymerase III;GO:0006383 transcription by RNA polymerase III;GO:0006386 termination of RNA polymerase III transcription;GO:0006384 transcription initiation at RNA polymerase III promoter;GO:0006354 DNA-templated transcription elongation", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P22276-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22336-1", "uniprot_id": "RFA1_YEAST", "mass": 70348.0, "length": 621, "protein_name": "Replication factor A protein 1", "gene_name": "RFA1", "organism": "Yeast", "refseq_name": "replication factor A subunit protein RFA1", "refseq_ac": "NP_009404", "gene_names_uniprotkb": "RFA1; BUF2; FUN3; RPA1", "gene_names_refseq": "BUF2; FUN3; RFA1; RPA1; RPA70", "protein_names_uniprotkb": "Replication factor A protein 1; DNA-binding protein BUF2; RF-A protein 1; Replication protein A 69 kDa DNA-binding subunit; Single-stranded DNA-binding protein", "protein_names_refseq": "replication factor A subunit protein RFA1", "tax_id": 559292, "disease": "", "pathway": " (sce:YAR007C)", "pathway_count": 1, "publication_count": 24, "publication_id_list": "14562106;14642562;16678108;17563356;18407956;1885001;19684113;19779198;19795423;19823750;20190278;20702584;21177495;2192864;22814378;23749301;24374639;30516470;32597660;33481703;33491328;7731988;7941740;8355713", "class_list": "", "function": "As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. Binds to single-stranded sequences participating in DNA replication in addition to those mediating transcriptional repression (URS1) and activation (CAR1). Stimulates the activity of a cognate strand exchange protein (SEP1). It cooperates with T-AG and DNA topoisomerase I to unwind template DNA containing the simian virus 40 origin of DNA replication., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VPL9;P38906", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0008270 zinc ion binding;GO:0003684 damaged DNA binding;GO:0003690 double-stranded DNA binding;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005662 DNA replication factor A complex", "go_biological_process": "GO:0006312 mitotic recombination;GO:0010833 telomere maintenance via telomere lengthening;GO:0006281 DNA repair;GO:0000723 telomere maintenance;GO:0006260 DNA replication", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "P22336-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22516-1", "uniprot_id": "CHL1_YEAST", "mass": 98806.0, "length": 861, "protein_name": "ATP-dependent DNA helicase CHL1", "gene_name": "CHL1", "organism": "Yeast", "refseq_name": "DNA helicase", "refseq_ac": "NP_015317", "gene_names_uniprotkb": "CHL1; CTF1; YP8132.05", "gene_names_refseq": "CHL1; CTF1; LPA9; MCM12", "protein_names_uniprotkb": "ATP-dependent DNA helicase CHL1; 5.6.2.3; Chromosome loss protein 1; Chromosome transmission fidelity protein 1; DNA 5'-3' helicase CHL1", "protein_names_refseq": "DNA helicase", "tax_id": 559292, "disease": "Warsaw breakage syndrome (Disease Ontology:DOID:0060535)", "pathway": " (sce:YPL008W)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10931920;14562106;14742714;15020404;15226378;19779198;19795423;19823750;2265610;23749301;24374639;30516470;33481703;33491328;9169875", "class_list": "", "function": "ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (PubMed:10931920). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (PubMed:14742714, PubMed:15020404). Has a specific role in chromosome segregation during meiosis II (PubMed:15226378)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W404", "ec_number_list": "3.6.4.13;5.6.2.3;3.6.4.10;3.6.-.-;5.6.2.4;3.6.4.-;5.6.1.4;3.6.4.12;3.6.4.6;5.6.2.5;3.6.1.-;2.3.2.27;3.1.-.-;3.4.24.-;3.6.5.-;2.7.4.3;2.7.11.1;7.2.2.-", "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0003678 DNA helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0036297 interstrand cross-link repair;GO:0007064 mitotic sister chromatid cohesion;GO:0031571 mitotic G1 DNA damage checkpoint signaling;GO:0034085 establishment of sister chromatid cohesion", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P22516-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22517-1", "uniprot_id": "KCC2_YEAST", "mass": 50447.0, "length": 447, "protein_name": "Calcium/calmodulin-dependent protein kinase II", "gene_name": "CMK2", "organism": "Yeast", "refseq_name": "calmodulin-dependent protein kinase CMK2", "refseq_ac": "NP_014626", "gene_names_uniprotkb": "CMK2", "gene_names_refseq": "CMK2", "protein_names_uniprotkb": "Calcium/calmodulin-dependent protein kinase II; 2.7.11.17", "protein_names_refseq": "calmodulin-dependent protein kinase CMK2", "tax_id": 559292, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); withdrawal disorder (Disease Ontology:DOID:0060001); alcohol use disorder (Disease Ontology:DOID:1574); cocaine dependence (Disease Ontology:DOID:9975)", "pathway": " (sce:YOL016C)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "14562106;17287358;17330950;17563356;18407956;19779198;2026147;20489023;2061341;20702584;23749301;24374639;32597660;33481703;33491328;9169874", "class_list": "", "function": "Important in cellular regulation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W250", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0004683 calcium/calmodulin-dependent protein kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006468 protein phosphorylation;GO:0007165 signal transduction;GO:0034599 cellular response to oxidative stress", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P22517-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22579-1", "uniprot_id": "SIN3_YEAST", "mass": 174839.0, "length": 1536, "protein_name": "Transcriptional regulatory protein SIN3", "gene_name": "SIN3", "organism": "Yeast", "refseq_name": "transcriptional regulator SIN3", "refseq_ac": "NP_014639", "gene_names_uniprotkb": "SIN3; CPE1; GAM2; RPD1; SDI1; SDS16; UME4", "gene_names_refseq": "CPE1; GAM2; RPD1; SDI1; SDS16; SIN3; UME4", "protein_names_uniprotkb": "Transcriptional regulatory protein SIN3", "protein_names_refseq": "transcriptional regulator SIN3", "tax_id": 559292, "disease": "developmental disorder of mental health (Disease Ontology:DOID:0060037); chromosome 15q24 deletion syndrome (Disease Ontology:DOID:0060395); Huntington's disease (Disease Ontology:DOID:12858); cancer (Disease Ontology:DOID:162); transient cerebral ischemia (Disease Ontology:DOID:224)", "pathway": " (sce:YOL004W)", "pathway_count": 1, "publication_count": 42, "publication_id_list": "10388812;10899127;10931932;11238941;11875433;12672825;12808094;14562106;14711989;14737171;15141165;15143171;15722108;1603074;16286008;16314178;17330950;17563356;18407956;1944290;19779198;19795423;19823750;20190278;20702584;21126336;21177495;2233725;23749301;24374639;30516470;32597660;33229814;33481703;33491328;8441414;8978024;9169874;9234741;9393435;9572144;9710596", "class_list": "", "function": "Catalytic component of the RPD3 histone deacetylase complexes RPD3C(L) and RPD3C(S) responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. SIN3 also has a RPD3 independent function required for normal longevity., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 5, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 5, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 5, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 37, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 5, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6W263;Q08049", "ec_number_list": "", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0042802 identical protein binding;GO:0003714 transcription corepressor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0070822 Sin3-type complex;GO:0070210 Rpd3L-Expanded complex;GO:0032221 Rpd3S complex", "go_biological_process": "GO:0030174 regulation of DNA-templated DNA replication initiation;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 4.9, "record_id": "P22579-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22768-1", "uniprot_id": "ASSY_YEAST", "mass": 46928.0, "length": 420, "protein_name": "Argininosuccinate synthase", "gene_name": "ARG1", "organism": "Yeast", "refseq_name": "argininosuccinate synthase", "refseq_ac": "NP_014583", "gene_names_uniprotkb": "ARG1; O1228", "gene_names_refseq": "ARG10; ARG1", "protein_names_uniprotkb": "Argininosuccinate synthase; 6.3.4.5; Citrulline--aspartate ligase", "protein_names_refseq": "argininosuccinate synthase", "tax_id": 559292, "disease": "classic citrullinemia (Disease Ontology:DOID:0070340); Alzheimer's disease (Disease Ontology:DOID:10652); uveitis (Disease Ontology:DOID:13141); melanoma (Disease Ontology:DOID:1909); hepatocellular carcinoma (Disease Ontology:DOID:684); citrullinemia (Disease Ontology:DOID:9273)", "pathway": " (sce:YOL058W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562095;14562106;205532;2123815;24374639;2897249;33491328;35347;8789261;9169874", "class_list": "", "function": "Catalyzes the eighth step in arginine biosynthesis. Also has a catabolic function as the first enzyme of citrulline utilization as nitrogen source via arginine and the reactions involved in the arginase pathway., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W209", "ec_number_list": "6.3.4.5", "go_molecular_function": "GO:0005524 ATP binding;GO:0004055 argininosuccinate synthase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0000050 urea cycle;GO:0000053 argininosuccinate metabolic process;GO:0006526 L-arginine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P22768-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22803-1", "uniprot_id": "TRX2_YEAST", "mass": 11204.0, "length": 104, "protein_name": "Thioredoxin-2", "gene_name": "TRX2", "organism": "Yeast", "refseq_name": "thioredoxin TRX2", "refseq_ac": "NP_011725", "gene_names_uniprotkb": "TRX2; G7746; TRX1", "gene_names_refseq": "LMA1; TRX2", "protein_names_uniprotkb": "Thioredoxin-2; TR-II; Thioredoxin II; Thioredoxin-1", "protein_names_refseq": "thioredoxin TRX2", "tax_id": 559292, "disease": "dilated cardiomyopathy (Disease Ontology:DOID:12930); glaucoma (Disease Ontology:DOID:1686); myocardial infarction (Disease Ontology:DOID:5844); myocarditis (Disease Ontology:DOID:820); intermediate coronary syndrome (Disease Ontology:DOID:8805); steatotic liver disease (Disease Ontology:DOID:9452)", "pathway": " (sce:YGR209C)", "pathway_count": 1, "publication_count": 28, "publication_id_list": "10681558;11013218;11018134;11169096;12410842;12437921;12914955;14562095;14562106;17044062;17322287;18407956;19779198;1988444;2026619;21126336;22106047;24374639;3060034;33481703;33491328;4945270;7961686;8904340;9015301;9169869;9657146;9988687", "class_list": "", "function": "Participates as a hydrogen donor in redox reactions through the reversible oxidation of its active center dithiol to a disulfide, accompanied by the transfer of 2 electrons and 2 protons. It is involved in many cellular processes, including deoxyribonucleotide synthesis, repair of oxidatively damaged proteins, protein folding, sulfur metabolism, and redox homeostasis. Thioredoxin-dependent enzymes include phosphoadenosine-phosphosulfate reductase MET16, alkyl-hydroperoxide reductase DOT5, thioredoxin peroxidases TSA1 and TSA2, alkyl hydroperoxide reductase AHP1, and peroxiredoxin HYR1. Thioredoxin is also involved in protection against reducing stress. As part of the LMA1 complex, it is involved in the facilitation of vesicle fusion such as homotypic vacuole and ER-derived COPII vesicle fusion with the Golgi. This activity does not require the redox mechanism. Through its capacity to inactivate the stress response transcription factor YAP1 and its regulator the hydroperoxide stress sensor HYR1, it is involved in feedback regulation of stress response gene expression upon oxidative stress., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUZ2", "ec_number_list": "", "go_molecular_function": "GO:0015036 disulfide oxidoreductase activity;GO:0015035 protein-disulfide reductase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0080058 protein deglutathionylation;GO:0042144 vacuole fusion, non-autophagic;GO:0015031 protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0045454 cell redox homeostasis", "synthesized_glycan_count": 0, "hit_score": 2.9, "record_id": "P22803-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22804-1", "uniprot_id": "BET1_YEAST", "mass": 15720.0, "length": 142, "protein_name": "Protein transport protein BET1", "gene_name": "BET1", "organism": "Yeast", "refseq_name": "Bet1p", "refseq_ac": "NP_012262", "gene_names_uniprotkb": "BET1; SLY12; YIA4C", "gene_names_refseq": "BET1; SLY12", "protein_names_uniprotkb": "Protein transport protein BET1; Protein SLY12; Suppressor of loss of YPT1 protein 12", "protein_names_refseq": "Bet1p", "tax_id": 559292, "disease": "congenital muscular dystrophy with rapid progression (Disease Ontology:DOID:0061202); uterine fibroid (Disease Ontology:DOID:13223); endometrial adenocarcinoma (Disease Ontology:DOID:2870)", "pathway": " (sce:YIL004C); (R-SCE-204005); (R-SCE-6807878); (R-SCE-6811438)", "pathway_count": 4, "publication_count": 8, "publication_id_list": "11001058;12941276;1396561;1990290;24374639;33491328;7762303;9169870", "class_list": "", "function": "SNARE required for targeting and fusion of ER-derived transport vesicles with the Golgi complex., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVS6", "ec_number_list": "", "go_molecular_function": "GO:0005484 SNAP receptor activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0016020 membrane;GO:0030134 COPII-coated ER to Golgi transport vesicle;GO:0005789 endoplasmic reticulum membrane;GO:0031201 SNARE complex", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0006906 vesicle fusion;GO:0048280 vesicle fusion with Golgi apparatus", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P22804-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22855-1", "uniprot_id": "MAN1_YEAST", "mass": 124499.0, "length": 1083, "protein_name": "Alpha-mannosidase", "gene_name": "AMS1", "organism": "Yeast", "refseq_name": "alpha-mannosidase", "refseq_ac": "NP_011359", "gene_names_uniprotkb": "AMS1; G1861", "gene_names_refseq": "AMS1", "protein_names_uniprotkb": "Alpha-mannosidase; 3.2.1.24; Alpha-D-mannoside mannohydrolase", "protein_names_refseq": "alpha-mannosidase", "tax_id": 559292, "disease": "congenital disorder of deglycosylation 2 (Disease Ontology:DOID:0060990)", "pathway": " (sce:YGL156W); (R-SCE-8853383)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "11264288;12723970;14562106;19779198;2266133;22814378;24374639;2675832;33491328;8585324;9169869", "class_list": "", "function": "Degrades free oligosaccharides in the vacuole., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VTZ5", "ec_number_list": "3.2.1.24", "go_molecular_function": "GO:0046872 metal ion binding;GO:0030246 carbohydrate binding;GO:0004559 alpha-mannosidase activity", "go_cellular_component": "GO:0000329 fungal-type vacuole membrane;GO:0034270 Cvt complex", "go_biological_process": "GO:0042149 cellular response to glucose starvation;GO:0006995 cellular response to nitrogen starvation;GO:0009313 oligosaccharide catabolic process;GO:0019309 mannose catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P22855-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22936-1", "uniprot_id": "APN1_YEAST", "mass": 41439.0, "length": 367, "protein_name": "Apurinic-apyrimidinic endonuclease 1", "gene_name": "APN1", "organism": "Yeast", "refseq_name": "DNA-(apurinic or apyrimidinic site) lyase APN1", "refseq_ac": "NP_012808", "gene_names_uniprotkb": "APN1; YKL513", "gene_names_refseq": "APN1", "protein_names_uniprotkb": "Apurinic-apyrimidinic endonuclease 1; 3.1.21.-; AP endonuclease 1", "protein_names_refseq": "DNA-(apurinic or apyrimidinic site) lyase APN1", "tax_id": 559292, "disease": "", "pathway": " (sce:YKL114C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "14562106;1561835;1693433;1720775;18407956;19779198;21126336;24374639;27017623;3056935;33481703;33491328;8196765", "class_list": "", "function": "DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. APN1 accounts for > 97% of both apurinic/apyrimidinic (AP) endonuclease and DNA 3'-repair diesterase activities., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXH4", "ec_number_list": "", "go_molecular_function": "GO:0008296 3'-5'-DNA exonuclease activity;GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity;GO:0008081 phosphoric diester hydrolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion", "go_biological_process": "GO:0006284 base-excision repair", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P22936-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22943-1", "uniprot_id": "HSP12_YEAST", "mass": 11693.0, "length": 109, "protein_name": "12 kDa heat shock protein", "gene_name": "HSP12", "organism": "Yeast", "refseq_name": "lipid-binding protein HSP12", "refseq_ac": "NP_116640", "gene_names_uniprotkb": "HSP12; GLP1; HOR5", "gene_names_refseq": "GLP1; HOR5; HSP12", "protein_names_uniprotkb": "12 kDa heat shock protein; Glucose and lipid-regulated protein", "protein_names_refseq": "lipid-binding protein HSP12", "tax_id": 559292, "disease": "", "pathway": " (sce:YFL014W)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "11816034;14562106;17287358;17322287;17563356;18407956;19779198;19795423;19823750;20190278;21126336;21177495;2129531;2175390;22218487;23749301;24374639;33481703;33491328;7670463", "class_list": "", "function": "May play a role in a switch from carbohydrate utilizing metabolism to fatty acid utilizing metabolism., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTL5;Q8X145", "ec_number_list": "", "go_molecular_function": "GO:0008289 lipid binding;GO:0044183 protein folding chaperone", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005768 endosome;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0007009 plasma membrane organization;GO:0007155 cell adhesion;GO:0034605 cellular response to heat;GO:0034599 cellular response to oxidative stress;GO:0071470 cellular response to osmotic stress", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P22943-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P23179-1", "uniprot_id": "SPO11_YEAST", "mass": 45413.0, "length": 398, "protein_name": "Meiosis-specific protein SPO11", "gene_name": "SPO11", "organism": "Yeast", "refseq_name": "DNA topoisomerase (ATP-hydrolyzing)", "refseq_ac": "NP_011841", "gene_names_uniprotkb": "SPO11", "gene_names_refseq": "SPO11", "protein_names_uniprotkb": "Meiosis-specific protein SPO11; 5.6.2.2; Sporulation-specific protein 11", "protein_names_refseq": "DNA topoisomerase (ATP-hydrolyzing)", "tax_id": 559292, "disease": "", "pathway": " (sce:YHL022C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "11983174;14992724;17322287;24374639;3317399;33658710;34108684;39304764;7926789;8091229;9039264;9121560", "class_list": "", "function": "DNA endonuclease, which specifically mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination (PubMed:11983174, PubMed:14992724, PubMed:33658710, PubMed:34108684, PubMed:39304764, PubMed:9039264). SPO11 covalently attaches itself to the 5' DNA strand during DSB formation and each strand is cleaved by a composite active site assembled at the interface of two SPO11 monomers, with the two cleavages staggered to produce a two-nucleotide 5' overhang (By similarity). SPO11 cleavage site selection is driven by a mild sequence bias and a preference for bendable and underwound DNA (PubMed:33658710, PubMed:34108684)., [UniProtKB, PubMed, PubMed, PubMed, UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DKP3", "ec_number_list": "3.6.-.-;5.6.2.2;3.1.-.-", "go_molecular_function": "GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity;GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0005654 nucleoplasm;GO:0035861 site of double-strand break;GO:0000228 nuclear chromosome", "go_biological_process": "GO:0007130 synaptonemal complex assembly;GO:0007129 homologous chromosome pairing at meiosis;GO:0042138 meiotic DNA double-strand break formation;GO:0000706 meiotic DNA double-strand break processing;GO:0007131 reciprocal meiotic recombination", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P23179-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P23201-1", "uniprot_id": "SPA2_YEAST", "mass": 163143.0, "length": 1466, "protein_name": "Scaffold protein SPA2", "gene_name": "SPA2", "organism": "Yeast", "refseq_name": "Spa2p", "refseq_ac": "NP_013079", "gene_names_uniprotkb": "SPA2; L1209; PEA1", "gene_names_refseq": "FUS6; PEA1; PPF1; SPA2", "protein_names_uniprotkb": "Scaffold protein SPA2", "protein_names_refseq": "Spa2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLL021W)", "pathway_count": 1, "publication_count": 29, "publication_id_list": "12361575;14562106;15665377;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;2211820;22218487;23749301;24374639;30516470;31362951;31699995;32597660;33229814;33481703;33491328;34965436;9046100;9169871;9790978", "class_list": "", "function": "Acts as a scaffolding protein at sites of polarized growth (PubMed:12361575, PubMed:31362951). Plays a role in the establishment of polarized growth (PubMed:12361575). Recruits components of the cell integrity MAPK cascade to sites of polarized growth (PubMed:12361575). Localizes actin assembly proteins BUD6 and AIP5 to sites of polarized growth to promote actin nucleation and the formation of actin filament seeds (PubMed:31362951, PubMed:31699995). Involved in pheromone-induced morphogenesis and efficient mating (PubMed:2211820)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 16, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 16, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 16, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 116, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 16, "binding_glycan_count": 0, "secondary_ac_list": "D6VXY3", "ec_number_list": "", "go_molecular_function": "GO:0005078 MAP-kinase scaffold activity", "go_cellular_component": "GO:0005938 cell cortex;GO:0005826 actomyosin contractile ring;GO:1902716 cell cortex of growing cell tip;GO:0000131 incipient cellular bud site;GO:0000133 polarisome", "go_biological_process": "GO:0032956 regulation of actin cytoskeleton organization;GO:0032880 regulation of protein localization;GO:0008360 regulation of cell shape;GO:0071474 cellular hyperosmotic response;GO:0006903 vesicle targeting", "synthesized_glycan_count": 0, "hit_score": 4.7, "record_id": "P23201-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P23202-1", "uniprot_id": "URE2_YEAST", "mass": 40271.0, "length": 354, "protein_name": "Transcriptional regulator URE2", "gene_name": "URE2", "organism": "Yeast", "refseq_name": "glutathione peroxidase", "refseq_ac": "NP_014170", "gene_names_uniprotkb": "URE2; N1165", "gene_names_refseq": "URE2", "protein_names_uniprotkb": "Transcriptional regulator URE2; 1.11.1.9; 1.8.4.-; Disulfide reductase; Glutathione peroxidase", "protein_names_refseq": "glutathione peroxidase", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL229C)", "pathway_count": 1, "publication_count": 26, "publication_id_list": "10604478;10799523;11073991;11171973;11342133;11695904;12177423;14562106;15371425;16060675;17953455;18407956;19321443;1990286;20489023;21126336;22814378;23749301;24374639;32597660;33491328;7569955;7909170;8755910;8896273;9169873", "class_list": "", "function": "Plays an important role in nitrogen catabolite repression. Down-regulates the expression of many genes involved in nitrogen utilization by inhibiting the GATA transcriptional activators GLN3 and GAT1. Under good nitrogen conditions, binds to the phosphorylated forms of GLN3 and GAT1 and sequesters them in the cytoplasm, preventing transcription of genes expressed upon nitrogen limitation. Is also an atypical glutaredoxin without a catalytical cysteine residue. Has glutathione peroxidase and thiol:disulfide oxidoreductase activities in both native and fibrillar form. Also shows insulin disulfide reductase and dehydroascorbic acid reductase (DHAR) activities., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0W3", "ec_number_list": "1.11.1.9;2.5.1.18;1.8.4.-;1.11.1.24", "go_molecular_function": "GO:0004364 glutathione transferase activity;GO:0003714 transcription corepressor activity;GO:0051219 phosphoprotein binding;GO:0004602 glutathione peroxidase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006808 regulation of nitrogen utilization;GO:0032447 protein urmylation;GO:0042128 nitrate assimilation", "synthesized_glycan_count": 0, "hit_score": 2.7, "record_id": "P23202-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P23255-1", "uniprot_id": "TAF2_YEAST", "mass": 161471.0, "length": 1407, "protein_name": "Transcription initiation factor TFIID subunit 2", "gene_name": "TAF2", "organism": "Yeast", "refseq_name": "transcription initiation factor TFIID subunit TAF2", "refseq_ac": "NP_009971", "gene_names_uniprotkb": "TAF2; TAF150; TSM1; YCR42C; YCR724", "gene_names_refseq": "TAF150; TAF2; TSM1", "protein_names_uniprotkb": "Transcription initiation factor TFIID subunit 2; TAFII-150; TBP-associated factor 150 kDa; TBP-associated factor 2; TSM-1", "protein_names_refseq": "transcription initiation factor TFIID subunit TAF2", "tax_id": 559292, "disease": "autosomal recessive intellectual developmental disorder 40 (Disease Ontology:DOID:0081205)", "pathway": " (sce:YCR042C); (R-SCE-674695); (R-SCE-73776); (R-SCE-73779); (R-SCE-75953); (R-SCE-76042)", "pathway_count": 6, "publication_count": 21, "publication_id_list": "10788514;12093743;12138208;12516863;14562106;1574125;17287358;17330950;17563356;1789011;1840512;18407956;19779198;20702584;23749301;24374639;30516470;32597660;33481703;33491328;7667272", "class_list": "", "function": "Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 17, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VR51", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0000976 transcription cis-regulatory region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005669 transcription factor TFIID complex", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006366 transcription by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P23255-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P23292-1", "uniprot_id": "KC12_YEAST", "mass": 62079.0, "length": 546, "protein_name": "Casein kinase I homolog 2", "gene_name": "YCK2", "organism": "Yeast", "refseq_name": "serine/threonine protein kinase YCK2", "refseq_ac": "NP_014245", "gene_names_uniprotkb": "YCK2; CKI1; N1755", "gene_names_refseq": "YCK2", "protein_names_uniprotkb": "Casein kinase I homolog 2; 2.7.11.1", "protein_names_refseq": "serine/threonine protein kinase YCK2", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL154C)", "pathway_count": 1, "publication_count": 21, "publication_id_list": "10866691;12370247;14562106;15105419;1627830;1729698;17330950;18407956;19779198;20702584;22106047;22814378;23749301;24374639;30516470;32597660;33481703;33491328;34965436;8686380;9169873", "class_list": "", "function": "Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 23, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W129", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:0005935 cellular bud neck", "go_biological_process": "GO:0006897 endocytosis;GO:0007165 signal transduction;GO:0000902 cell morphogenesis;GO:0009749 response to glucose;GO:0010255 glucose mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P23292-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P23293-1", "uniprot_id": "BUR1_YEAST", "mass": 74239.0, "length": 657, "protein_name": "Serine/threonine-protein kinase BUR1", "gene_name": "SGV1", "organism": "Yeast", "refseq_name": "cyclin-dependent serine/threonine protein kinase SGV1", "refseq_ac": "NP_015487", "gene_names_uniprotkb": "SGV1; BUR1; P9584.8", "gene_names_refseq": "BUR1; SGV1", "protein_names_uniprotkb": "Serine/threonine-protein kinase BUR1; 2.7.11.22; 2.7.11.23; Bypass UAS requirement protein 1; Suppressor of GPA1-Vall50 mutation protein 1", "protein_names_refseq": "cyclin-dependent serine/threonine protein kinase SGV1", "tax_id": 559292, "disease": "renal carcinoma (Disease Ontology:DOID:4451); congestive heart failure (Disease Ontology:DOID:6000)", "pathway": " (sce:YPR161C); (R-SCE-674695); (R-SCE-6796648); (R-SCE-6807505); (R-SCE-9018519)", "pathway_count": 5, "publication_count": 33, "publication_id_list": "10982824;11390638;11875433;12215532;12972617;14562095;14562106;15665377;16040246;16307922;17287358;17330950;17563356;1828190;18407956;19684113;19779198;19795423;19823750;20489023;20702584;21126336;21177495;22218487;23749301;24374639;24440502;32597660;33481703;33491328;7871892;8293972;9169875", "class_list": "", "function": "Serine/threonine-protein kinase component of the BUR kinase complex involved in transcription regulation. This complex phosphorylates 'Ser-120' of the UBC2/RAD6 ubiquitin-conjugating enzyme (E2), leading to monoubiquitination of histone H2B, the localization of the PAF1 complex to the chromatin, and the silencing of telomeric-associated genes. Also required for histone H3 'Lys-4' trimethylation. May phosphorylate the 'Ser-5' of the RBP1 carboxy-terminal domain (CTD) repeats. Necessary for the recovery from pheromone-induced growth arrest in the cell cycle G1 phase. The kinase activity of the complex requires the presence of BUR2., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W4G2", "ec_number_list": "2.7.11.22;2.7.7.6;2.7.11.11;2.7.11.23;2.7.11.1;2.7.12.2;5.6.2.3;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.1.3.16;3.6.-.-;5.6.2.4;3.6.1.-", "go_molecular_function": "GO:0005524 ATP binding;GO:0004693 cyclin-dependent protein serine/threonine kinase activity;GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000307 cyclin-dependent protein kinase holoenzyme complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006368 transcription elongation by RNA polymerase II;GO:0032968 positive regulation of transcription elongation by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 3.4, "record_id": "P23293-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P23301-1", "uniprot_id": "IF5A1_YEAST", "mass": 17114.0, "length": 157, "protein_name": "Eukaryotic translation initiation factor 5A-1", "gene_name": "HYP2", "organism": "Yeast", "refseq_name": "translation elongation factor eIF-5A", "refseq_ac": "NP_010880", "gene_names_uniprotkb": "HYP2; SYGP-ORF21; TIF51A", "gene_names_refseq": "HYP2; TIF51A", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 5A-1; Hypusine-containing protein HP2; eIF-4D; eIF-5A-1", "protein_names_refseq": "translation elongation factor eIF-5A", "tax_id": 559292, "disease": "pancreatic ductal adenocarcinoma (Disease Ontology:DOID:3498); pulmonary hypertension (Disease Ontology:DOID:6432); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (sce:YEL034W); (R-SCE-204626)", "pathway_count": 2, "publication_count": 46, "publication_id_list": "10229683;11861547;14675757;15665377;16157662;16215987;16408210;16914118;17330950;18341589;18407956;1903841;19120453;19338753;19424157;19684113;19779198;19795423;19823750;21177495;2135872;22106047;22218487;22814378;23727016;23749301;24374639;24923804;26715760;27115996;27196944;28392174;30516470;3119589;32597660;33481703;33491328;33502312;36804914;641056;8243648;8307948;8314769;8325852;9169868;9582285", "class_list": "", "function": "Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts (PubMed:10229683, PubMed:16157662, PubMed:16914118, PubMed:19338753, PubMed:19424157, PubMed:23727016, PubMed:24923804, PubMed:28392174, PubMed:36804914, PubMed:641056, PubMed:8307948, PubMed:9582285). Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome (PubMed:23727016, PubMed:24923804, PubMed:28392174). Acts as a ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step (PubMed:36804914). Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity (PubMed:16408210)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 17, "reported_mutagensis": 30, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLL5", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0003746 translation elongation factor activity;GO:0043022 ribosome binding;GO:0003743 translation initiation factor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0072344 rescue of stalled ribosome;GO:0002184 cytoplasmic translational termination;GO:0006452 translational frameshifting;GO:0045901 positive regulation of translational elongation;GO:0045905 positive regulation of translational termination", "synthesized_glycan_count": 0, "hit_score": 4.7, "record_id": "P23301-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P23337-1", "uniprot_id": "GYS1_YEAST", "mass": 80510.0, "length": 708, "protein_name": "Glycogen [starch] synthase isoform 1", "gene_name": "GSY1", "organism": "Yeast", "refseq_name": "glycogen (starch) synthase GSY1", "refseq_ac": "NP_116670", "gene_names_uniprotkb": "GSY1", "gene_names_refseq": "GSY1", "protein_names_uniprotkb": "Glycogen [starch] synthase isoform 1; 2.4.1.11", "protein_names_refseq": "glycogen (starch) synthase GSY1", "tax_id": 559292, "disease": "cardiovascular system disease (Disease Ontology:DOID:1287); glycogen storage disease (Disease Ontology:DOID:2747); Lafora disease (Disease Ontology:DOID:3534)", "pathway": " (sce:YFR015C); (R-SCE-3322077)", "pathway_count": 2, "publication_count": 25, "publication_id_list": "11875433;14562106;15665377;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20489023;20702584;21126336;21177495;2123485;22218487;23749301;24374639;30516470;32597660;33481703;33491328;34965436;7670463", "class_list": "", "function": "Glycogen synthase participates in the glycogen biosynthetic process along with glycogenin and glycogen branching enzyme. Extends the primer composed of a few glucose units formed by glycogenin by adding new glucose units to it. In this context, glycogen synthase transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTP6", "ec_number_list": "2.4.1.11;2.4.1.18;2.4.1.186", "go_molecular_function": "GO:0004373 alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0042587 glycogen granule", "go_biological_process": "GO:0005978 glycogen biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 2.6, "record_id": "P23337-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P23394-1", "uniprot_id": "PRP28_YEAST", "mass": 66641.0, "length": 588, "protein_name": "Pre-mRNA-splicing ATP-dependent RNA helicase PRP28", "gene_name": "PRP28", "organism": "Yeast", "refseq_name": "mRNA splicing protein PRP28", "refseq_ac": "NP_010529", "gene_names_uniprotkb": "PRP28; YD8419.10C", "gene_names_refseq": "PRP28", "protein_names_uniprotkb": "Pre-mRNA-splicing ATP-dependent RNA helicase PRP28; 3.6.4.13; Helicase CA8", "protein_names_refseq": "mRNA splicing protein PRP28", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR243C)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "10024879;11172727;11720284;14562095;17287358;18407956;19779198;2010088;21126336;23749301;2406722;24374639;30516470;32597660;33481703;33491328;7520570;9169867;9396812", "class_list": "", "function": "ATP-dependent RNA helicase involved in mRNA splicing. May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site. May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 31, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VSM3;P20450", "ec_number_list": "3.6.4.13;5.6.2.3;3.6.4.10;3.6.-.-;5.6.2.4;3.6.4.-;5.6.1.4;3.6.4.12;3.6.4.6;5.6.2.5;3.6.1.-;2.3.2.27;3.1.-.-;3.4.24.-;3.6.5.-;2.7.4.3;2.7.11.1;7.2.2.-", "go_molecular_function": "GO:0003723 RNA binding;GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0071013 catalytic step 2 spliceosome;GO:0005682 U5 snRNP", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0000395 mRNA 5'-splice site recognition", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P23394-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P23503-1", "uniprot_id": "NAR1_YEAST", "mass": 54151.0, "length": 491, "protein_name": "Cytosolic Fe-S cluster assembly factor NAR1", "gene_name": "NAR1", "organism": "Yeast", "refseq_name": "iron-sulfur cluster assembly protein NAR1", "refseq_ac": "NP_014159", "gene_names_uniprotkb": "NAR1; N1114", "gene_names_refseq": "NAR1", "protein_names_uniprotkb": "Cytosolic Fe-S cluster assembly factor NAR1; Nuclear architecture-related protein 1", "protein_names_refseq": "iron-sulfur cluster assembly protein NAR1", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL240C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "15103330;15667273;16314508;17322287;18407956;19385603;2269430;24374639;33481703;33491328;8896273;9169873", "class_list": "", "function": "Essential component of a cytosolic Fe/S protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 9, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0V3", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0051536 iron-sulfur cluster binding", "go_cellular_component": "GO:0097361 cytosolic [4Fe-4S] assembly targeting complex;GO:0005634 nucleus;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0016226 iron-sulfur cluster assembly", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P23503-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P23542-1", "uniprot_id": "AATC_YEAST", "mass": 46058.0, "length": 418, "protein_name": "Aspartate aminotransferase, cytoplasmic", "gene_name": "AAT2", "organism": "Yeast", "refseq_name": "aspartate transaminase AAT2", "refseq_ac": "NP_013127", "gene_names_uniprotkb": "AAT2; ASP5; L1746", "gene_names_refseq": "AAT2; ASP5; THR5", "protein_names_uniprotkb": "Aspartate aminotransferase, cytoplasmic; 2.6.1.1; Transaminase A", "protein_names_refseq": "aspartate transaminase AAT2", "tax_id": 559292, "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); early infantile epileptic encephalopathy (Disease Ontology:DOID:0050709); developmental and epileptic encephalopathy 82 (Disease Ontology:DOID:0080715); transient cerebral ischemia (Disease Ontology:DOID:224); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); pancreatic ductal adenocarcinoma (Disease Ontology:DOID:3498); amyloidosis (Disease Ontology:DOID:9120)", "pathway": " (sce:YLR027C); (R-SCE-8963693); (R-SCE-9856872)", "pathway_count": 3, "publication_count": 12, "publication_id_list": "14562106;17287358;1859361;2199266;22814378;24374639;33481703;33491328;6811576;9169871;9288922;9655342", "class_list": "", "function": "Plays a key role in amino acid metabolism., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VY29", "ec_number_list": "2.6.1.1", "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity;GO:0043023 ribosomal large subunit binding", "go_cellular_component": "GO:0005777 peroxisome;GO:0005829 cytosol", "go_biological_process": "GO:0006103 2-oxoglutarate metabolic process;GO:0006536 glutamate metabolic process;GO:0006531 aspartate metabolic process;GO:0006532 aspartate biosynthetic process;GO:0032938 negative regulation of translation in response to oxidative stress", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P23542-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P23561-1", "uniprot_id": "STE11_YEAST", "mass": 80721.0, "length": 717, "protein_name": "Serine/threonine-protein kinase STE11", "gene_name": "STE11", "organism": "Yeast", "refseq_name": "mitogen-activated protein kinase kinase kinase STE11", "refseq_ac": "NP_013466", "gene_names_uniprotkb": "STE11; L8039.10", "gene_names_refseq": "STE11", "protein_names_uniprotkb": "Serine/threonine-protein kinase STE11; 2.7.11.25", "protein_names_refseq": "mitogen-activated protein kinase kinase kinase STE11", "tax_id": 559292, "disease": "alcohol use disorder (Disease Ontology:DOID:1574); amphetamine abuse (Disease Ontology:DOID:670)", "pathway": " (sce:YLR362W); (R-SCE-2559580)", "pathway_count": 2, "publication_count": 19, "publication_id_list": "10837245;14562106;15200959;15327964;15544813;1628833;17330950;17563356;18407956;19779198;20702584;21126336;2276621;23749301;24374639;32597660;33481703;33491328;9169871", "class_list": "", "function": "Serine/threonine protein kinase required for cell-type-specific transcription and signal transduction in yeast. It is thought that it phosphorylates the STE7 protein kinase which itself, phosphorylates the FUS3 and or KSS1 kinases., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ00", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0032093 SAM domain binding;GO:0004672 protein kinase activity;GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0004709 MAP kinase kinase kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0007254 JNK cascade;GO:0071474 cellular hyperosmotic response;GO:0038066 p38MAPK cascade;GO:0071507 pheromone response MAPK cascade;GO:0000196 cell integrity MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P23561-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P23585-1", "uniprot_id": "HXT2_YEAST", "mass": 59841.0, "length": 541, "protein_name": "High-affinity glucose transporter HXT2", "gene_name": "HXT2", "organism": "Yeast", "refseq_name": "hexose transporter HXT2", "refseq_ac": "NP_013724", "gene_names_uniprotkb": "HXT2; YM8270.15", "gene_names_refseq": "HXT2", "protein_names_uniprotkb": "High-affinity glucose transporter HXT2", "protein_names_refseq": "hexose transporter HXT2", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR011W)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "11875433;15652479;15665377;16847258;17330950;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22218487;2233722;22814378;23749301;24374639;30516470;32597660;33481703;33491328;9169872", "class_list": "", "function": "High-affinity glucose transporter. Is only indispensable for growth on low glucose-containing media, because S.cerevisiae possesses other sugar transporters., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 17, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VZI5", "ec_number_list": "", "go_molecular_function": "GO:0005353 fructose transmembrane transporter activity;GO:0015578 mannose transmembrane transporter activity;GO:0005351 carbohydrate:proton symporter activity;GO:0055056 D-glucose transmembrane transporter activity;GO:0015146 pentose transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:1904659 D-glucose transmembrane transport;GO:0008643 carbohydrate transport", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P23585-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P23594-1", "uniprot_id": "PP2A1_YEAST", "mass": 41938.0, "length": 369, "protein_name": "Serine/threonine-protein phosphatase PP2A-1 catalytic subunit", "gene_name": "PPH21", "organism": "Yeast", "refseq_name": "phosphoprotein phosphatase 2A catalytic subunit PPH21", "refseq_ac": "NP_010147", "gene_names_uniprotkb": "PPH21; D2180", "gene_names_refseq": "PPH21", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase PP2A-1 catalytic subunit; 3.1.3.16", "protein_names_refseq": "phosphoprotein phosphatase 2A catalytic subunit PPH21", "tax_id": 559292, "disease": "prostate cancer (Disease Ontology:DOID:10283); Parkinson's disease (Disease Ontology:DOID:14330); congestive heart failure (Disease Ontology:DOID:6000); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (sce:YDL134C); (R-SCE-198753); (R-SCE-202670); (R-SCE-389513); (R-SCE-6811558); (R-SCE-69273); (R-SCE-975957)", "pathway_count": 7, "publication_count": 16, "publication_id_list": "11060018;11697862;14551259;14562106;15447631;15689491;15947195;1656215;18407956;19779198;20702584;2176150;24374639;33491328;8972577;9169867", "class_list": "", "function": "Exact function not known, phosphatase 2A performs an essential cellular function., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRL4", "ec_number_list": "3.6.5.-;2.7.11.1;3.1.3.16;3.1.3.43;5.6.2.3;5.6.2.5;3.1.3.48;3.1.1.89;2.7.11.24;2.1.1.233;3.6.4.13", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0000159 protein phosphatase type 2A complex;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0006417 regulation of translation;GO:0000082 G1/S transition of mitotic cell cycle;GO:0031929 TOR signaling;GO:2000786 positive regulation of autophagosome assembly", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P23594-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P23595-1", "uniprot_id": "PP2A2_YEAST", "mass": 43047.0, "length": 377, "protein_name": "Serine/threonine-protein phosphatase PP2A-2 catalytic subunit", "gene_name": "PPH22", "organism": "Yeast", "refseq_name": "phosphoprotein phosphatase 2A catalytic subunit PPH22", "refseq_ac": "NP_010093", "gene_names_uniprotkb": "PPH22; D1271; SIS4", "gene_names_refseq": "PPH22; PPH2", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase PP2A-2 catalytic subunit; 3.1.3.16", "protein_names_refseq": "phosphoprotein phosphatase 2A catalytic subunit PPH22", "tax_id": 559292, "disease": "prostate cancer (Disease Ontology:DOID:10283); Parkinson's disease (Disease Ontology:DOID:14330); congestive heart failure (Disease Ontology:DOID:6000); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (sce:YDL188C); (R-SCE-198753); (R-SCE-202670); (R-SCE-389513); (R-SCE-6811558); (R-SCE-69273)", "pathway_count": 6, "publication_count": 24, "publication_id_list": "11060018;11697862;14551259;14562106;15447631;1656215;17287358;17330950;17563356;18407956;1848673;19779198;20489023;20702584;21177495;2176150;23749301;24374639;30516470;32597660;33481703;33491328;8533471;9169867", "class_list": "", "function": "Exact function not known, phosphatase 2A performs an essential cellular function., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRG5", "ec_number_list": "2.7.11.1;3.1.3.16;3.1.3.43;3.1.3.48;3.1.1.89;2.7.11.24;2.1.1.233", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0000159 protein phosphatase type 2A complex;GO:0034399 nuclear periphery;GO:0000779 condensed chromosome, centromeric region", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0006417 regulation of translation;GO:0000086 G2/M transition of mitotic cell cycle;GO:0000082 G1/S transition of mitotic cell cycle;GO:0031929 TOR signaling", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "P23595-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P23615-1", "uniprot_id": "SPT6_YEAST", "mass": 168291.0, "length": 1451, "protein_name": "Transcription elongation factor SPT6", "gene_name": "SPT6", "organism": "Yeast", "refseq_name": "chromatin-remodeling histone chaperone SPT6", "refseq_ac": "NP_011631", "gene_names_uniprotkb": "SPT6; CRE2; G6169; SSN20", "gene_names_refseq": "CRE2; SPT6; SSN20", "protein_names_uniprotkb": "Transcription elongation factor SPT6; Chromatin elongation factor SPT6", "protein_names_refseq": "chromatin-remodeling histone chaperone SPT6", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR116W)", "pathway_count": 1, "publication_count": 29, "publication_id_list": "12934008;14562095;14562106;15531585;16455495;17287358;17330950;17563356;18407956;19683497;19684113;19779198;20702584;21126336;21177495;2201908;22218487;23749301;24374639;24909858;29905868;30516470;32597660;33481703;33491328;8108857;8905931;9169869;9450930", "class_list": "", "function": "Histone H3-H4 chaperone that plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression. Essential for viability., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 22, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUP7", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0042393 histone binding;GO:0031491 nucleosome binding;GO:0001073 transcription antitermination factor activity, DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0008023 transcription elongation factor complex;GO:0000791 euchromatin", "go_biological_process": "GO:0016973 poly(A)+ mRNA export from nucleus;GO:0034728 nucleosome organization;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006338 chromatin remodeling;GO:0006366 transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 3.0, "record_id": "P23615-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P23638-1", "uniprot_id": "PSA3_YEAST", "mass": 28714.0, "length": 258, "protein_name": "Proteasome subunit alpha type-3", "gene_name": "PRE9", "organism": "Yeast", "refseq_name": "proteasome core particle subunit alpha 3", "refseq_ac": "NP_011651", "gene_names_uniprotkb": "PRE9; PRS5", "gene_names_refseq": "PRE9", "protein_names_uniprotkb": "Proteasome subunit alpha type-3; Macropain subunit Y13; Multicatalytic endopeptidase complex subunit Y13; Proteasome component Y13; Proteinase YSCE subunit 13", "protein_names_refseq": "proteasome core particle subunit alpha 3", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR135W); (R-SCE-1236974); (R-SCE-1236978); (R-SCE-5668541); (R-SCE-5689880); (R-SCE-9907900); (R-SCE-9912633)", "pathway_count": 7, "publication_count": 17, "publication_id_list": "11062564;11081519;14557538;14562106;16531229;16608349;16793518;1898763;20227375;21126336;22106047;22927375;24374639;32597660;33491328;9087403;9169869", "class_list": "", "function": "The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUR7", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0034515 proteasome storage granule;GO:0005634 nucleus;GO:0005829 cytosol;GO:0019773 proteasome core complex, alpha-subunit complex", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0080129 proteasome core complex assembly;GO:0010499 proteasomal ubiquitin-independent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P23638-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P23639-1", "uniprot_id": "PSA2_YEAST", "mass": 27162.0, "length": 250, "protein_name": "Proteasome subunit alpha type-2", "gene_name": "PRE8", "organism": "Yeast", "refseq_name": "proteasome core particle subunit alpha 2", "refseq_ac": "NP_013618", "gene_names_uniprotkb": "PRE8; PRS4", "gene_names_refseq": "PRE8", "protein_names_uniprotkb": "Proteasome subunit alpha type-2; Macropain subunit Y7; Multicatalytic endopeptidase complex subunit Y7; Proteasome component Y7; Proteinase YSCE subunit 7", "protein_names_refseq": "proteasome core particle subunit alpha 2", "tax_id": 559292, "disease": "", "pathway": " (sce:YML092C); (R-SCE-1236974); (R-SCE-1236978); (R-SCE-5668541); (R-SCE-5689880); (R-SCE-6798695); (R-SCE-9907900); (R-SCE-9912633)", "pathway_count": 8, "publication_count": 22, "publication_id_list": "11062564;11081519;14562106;16531229;16608349;16793518;17322287;18407956;1898763;20227375;20486117;21126336;21177495;22106047;22927375;23749301;24374639;27821475;33481703;33491328;9087403;9169872", "class_list": "", "function": "The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0J3", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0034515 proteasome storage granule;GO:0005634 nucleus;GO:0019773 proteasome core complex, alpha-subunit complex", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0010499 proteasomal ubiquitin-independent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "P23639-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P23642-1", "uniprot_id": "VAN1_YEAST", "mass": 61092.0, "length": 535, "protein_name": "Mannan polymerase I complex VAN1 subunit", "gene_name": "VAN1", "organism": "Yeast", "refseq_name": "Van1p", "refseq_ac": "NP_013592", "gene_names_uniprotkb": "VAN1; VRG7; YM8339.04C", "gene_names_refseq": "LDB13; VAN1; VRG7; VRG8", "protein_names_uniprotkb": "Mannan polymerase I complex VAN1 subunit; M-pol I subunit VAN1; Vanadate resistance protein", "protein_names_refseq": "Van1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YML115C)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "11095735;12235155;14562106;18407956;19779198;19795423;19823750;2137555;22218487;23749301;24374639;32597660;33481703;33491328;9169872;9430634;9434768", "class_list": "", "function": "Involved in regulation of the phosphorylation of a number of proteins, some of which appear to be important in cell growth control., [UniProtKB]; The M-Pol I complex possesses alpha-1,6-mannosyltransferase activity and is probably involved in the elongation of the mannan backbone of N-linked glycans on cell wall and periplasmic proteins., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6W0G9", "ec_number_list": "", "go_molecular_function": "GO:0000009 alpha-1,6-mannosyltransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0000136 mannan polymerase complex", "go_biological_process": "GO:0000032 cell wall mannoprotein biosynthetic process;GO:0006487 protein N-linked glycosylation;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P23642-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P23643-1", "uniprot_id": "VPS3_YEAST", "mass": 116922.0, "length": 1011, "protein_name": "Vacuolar protein sorting-associated protein 3", "gene_name": "VPS3", "organism": "Yeast", "refseq_name": "CORVET complex subunit VPS3", "refseq_ac": "NP_010783", "gene_names_uniprotkb": "VPS3; D9719.1; VPT17", "gene_names_refseq": "PEP6; VPL3; VPS3; VPT17", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 3; Vacuolar protein-targeting protein 17", "protein_names_refseq": "CORVET complex subunit VPS3", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR495C)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562106;2202738;23749301;24374639;33481703;33491328;9169867", "class_list": "", "function": "Required for sorting and processing of soluble vacuolar proteins, integrity of vacuolar morphology, efficient segregation of vacuolar material into the bud during the cell cycle, acidification of the vacuolar lumen, and assembly of the vacuolar H(+)-ATPase., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTB7", "ec_number_list": "", "go_molecular_function": "GO:0031267 small GTPase binding", "go_cellular_component": "GO:0030897 HOPS complex;GO:0005737 cytoplasm;GO:0005768 endosome;GO:0031901 early endosome membrane;GO:0033263 CORVET complex", "go_biological_process": "GO:0097352 autophagosome maturation;GO:0097576 vacuole fusion;GO:0007009 plasma membrane organization;GO:0016192 vesicle-mediated transport;GO:0000011 vacuole inheritance", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P23643-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P23724-1", "uniprot_id": "PSB6_YEAST", "mass": 26871.0, "length": 241, "protein_name": "Proteasome subunit beta type-6", "gene_name": "PRE7", "organism": "Yeast", "refseq_name": "proteasome core particle subunit beta 6", "refseq_ac": "NP_009512", "gene_names_uniprotkb": "PRE7; PRS3; PTS1; YBL0407", "gene_names_refseq": "PRE7; PRS3", "protein_names_uniprotkb": "Proteasome subunit beta type-6; Multicatalytic endopeptidase complex subunit C5; Proteasome component C5", "protein_names_refseq": "proteasome core particle subunit beta 6", "tax_id": 559292, "disease": "fetal alcohol spectrum disorder (Disease Ontology:DOID:0050696); intellectual disability (Disease Ontology:DOID:1059); microcephaly (Disease Ontology:DOID:10907); neurodegenerative disease (Disease Ontology:DOID:1289)", "pathway": " (sce:YBL041W)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "11062564;11081519;16531229;16608349;16793518;17287358;17322287;1734860;1773062;18407956;20227375;20486117;2194670;22927375;23749301;24374639;32597660;33481703;33491328;7813418;7871888;9087403", "class_list": "", "function": "Non-catalytic component of the proteasome which degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VPV7", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0019774 proteasome core complex, beta-subunit complex;GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0010499 proteasomal ubiquitin-independent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "P23724-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P23776-1", "uniprot_id": "EXG1_YEAST", "mass": 51311.0, "length": 448, "protein_name": "Glucan 1,3-beta-glucosidase I/II", "gene_name": "EXG1", "organism": "Yeast", "refseq_name": "glucan 1,3-beta-glucosidase", "refseq_ac": "NP_013403", "gene_names_uniprotkb": "EXG1; BGL1; L8003.3; SCW6", "gene_names_refseq": "BGL1; EXG1; SCW6", "protein_names_uniprotkb": "Glucan 1,3-beta-glucosidase I/II; 3.2.1.58; Exo-1,3-beta-glucanase I/II; Soluble cell wall protein 6", "protein_names_refseq": "glucan 1,3-beta-glucosidase", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR300W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "14562106;14730348;17322287;1900250;2125957;24374639;33491328;8298280;8488724;9169871;9748433", "class_list": "", "function": "Glucanases possibly play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme hydrolyzes both 1,3-beta- and 1,6-beta-linkages and even has beta-glucosidase activity. It could also function biosynthetically as a transglycosylase., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 2, "mined_n_glycosites": 2, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 2, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 2, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 2, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VYU4;Q9UR92", "ec_number_list": "", "go_molecular_function": "GO:0004338 glucan exo-1,3-beta-glucosidase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0000324 fungal-type vacuole;GO:0009277 fungal-type cell wall", "go_biological_process": "GO:0009251 glucan catabolic process;GO:0031505 fungal-type cell wall organization;GO:0044042 glucan metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P23776-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P23900-1", "uniprot_id": "FPS1_YEAST", "mass": 73877.0, "length": 669, "protein_name": "Glycerol uptake/efflux facilitator protein", "gene_name": "FPS1", "organism": "Yeast", "refseq_name": "Fps1p", "refseq_ac": "NP_013057", "gene_names_uniprotkb": "FPS1", "gene_names_refseq": "FPS1", "protein_names_uniprotkb": "Glycerol uptake/efflux facilitator protein", "protein_names_refseq": "Fps1p", "tax_id": 559292, "disease": "colitis (Disease Ontology:DOID:0060180); morbid obesity (Disease Ontology:DOID:11981); nephrogenic diabetes insipidus (Disease Ontology:DOID:12387); hypothyroidism (Disease Ontology:DOID:1459); brain ischemia (Disease Ontology:DOID:2316); brain edema (Disease Ontology:DOID:4724); ulcerative colitis (Disease Ontology:DOID:8577); Crohn's disease (Disease Ontology:DOID:8778); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (sce:YLL043W); (R-SCE-432030); (R-SCE-432040); (R-SCE-432047)", "pathway_count": 4, "publication_count": 21, "publication_id_list": "14562106;1648479;16847258;16885417;17330950;17563356;17620418;18407956;19779198;19795423;19823750;20702584;21177495;23749301;24374639;27607883;32597660;33481703;33491328;7729414;9169871", "class_list": "", "function": "Channel protein for glycerol. Has a role in both glycerol influx and efflux. Plays a role in osmoregulation: under osmotic stress the channel is apparently closed to allow accumulation of glycerol in the cell under hyperosmotic conditions., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 32, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VXW3", "ec_number_list": "", "go_molecular_function": "GO:0015168 glycerol transmembrane transporter activity;GO:0015250 water channel activity;GO:0015254 glycerol channel activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0006833 water transport;GO:0015793 glycerol transmembrane transport;GO:0006071 glycerol metabolic process;GO:0015791 polyol transmembrane transport;GO:0006846 acetate transport", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P23900-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P23968-1", "uniprot_id": "VATO_YEAST", "mass": 22596.0, "length": 213, "protein_name": "V-type proton ATPase subunit c''", "gene_name": "VMA16", "organism": "Yeast", "refseq_name": "H(+)-transporting V0 sector ATPase subunit c''", "refseq_ac": "NP_011891", "gene_names_uniprotkb": "VMA16; PPA1", "gene_names_refseq": "PPA1; VMA16", "protein_names_uniprotkb": "V-type proton ATPase subunit c''; V-ATPase 22 kDa proteolipid subunit; V-ATPase subunit c''; Vacuolar proton pump c'' subunit", "protein_names_refseq": "H(+)-transporting V0 sector ATPase subunit c''", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR026W); (R-SCE-1222556); (R-SCE-77387); (R-SCE-917977); (R-SCE-9639288)", "pathway_count": 5, "publication_count": 8, "publication_id_list": "16847258;17322287;2139779;24374639;27776355;29526695;8091229;9030535", "class_list": "", "function": "Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:9030535). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (PubMed:9030535)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DKX3", "ec_number_list": "", "go_molecular_function": "GO:0008553 P-type proton-exporting transporter activity;GO:0046961 proton-transporting ATPase activity, rotational mechanism", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0016020 membrane;GO:0016471 vacuolar proton-transporting V-type ATPase complex;GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0048388 endosomal lumen acidification;GO:0007035 vacuolar acidification;GO:1902600 proton transmembrane transport;GO:0061795 Golgi lumen acidification", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P23968-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P24004-1", "uniprot_id": "PEX1_YEAST", "mass": 117276.0, "length": 1043, "protein_name": "Peroxisomal ATPase PEX1", "gene_name": "PEX1", "organism": "Yeast", "refseq_name": "AAA family ATPase peroxin 1", "refseq_ac": "NP_012724", "gene_names_uniprotkb": "PEX1; PAS1", "gene_names_refseq": "PAS1; PEX1", "protein_names_uniprotkb": "Peroxisomal ATPase PEX1; 3.6.4.-; Peroxin-1; Peroxisomal assembly protein 1; Peroxisome biogenesis protein PAS1", "protein_names_refseq": "AAA family ATPase peroxin 1", "tax_id": 559292, "disease": "peroxisomal biogenesis disorder (Disease Ontology:DOID:0080377); peroxisome biogenesis disorder 1A (Disease Ontology:DOID:0080476); Heimler syndrome 1 (Disease Ontology:DOID:0080623); peroxisome biogenesis disorder 1B (Disease Ontology:DOID:0081240); Zellweger syndrome (Disease Ontology:DOID:905)", "pathway": " (sce:YKL197C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "14562095;14562106;15634331;16007078;16911527;1825027;24374639;26066397;26170309;29321502;33491328;7725796;8196765", "class_list": "", "function": "Component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling (PubMed:15634331, PubMed:16007078, PubMed:16911527, PubMed:26066397, PubMed:26170309, PubMed:29321502). Specifically recognizes PEX5 monoubiquitinated at 'Cys-6', and pulls it out of the peroxisome lumen through the PEX2-PEX10-PEX12 retrotranslocation channel (PubMed:26066397, PubMed:26170309, PubMed:29321502). Extraction by the PEX1-PEX6 AAA ATPase complex is accompanied by unfolding of the TPR repeats and release of bound cargo from PEX5 (PubMed:29321502)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 10, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VX03", "ec_number_list": "3.6.4.13;5.6.2.3;3.6.4.10;3.6.-.-;5.6.2.4;3.6.4.-;5.6.1.4;3.6.4.12;3.6.4.6;5.6.2.5;3.6.1.-;2.3.2.27;3.1.-.-;3.4.24.-;3.6.5.-;2.7.4.3;2.7.11.1;7.2.2.-", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140318 protein transporter activity", "go_cellular_component": "GO:0005777 peroxisome;GO:0005778 peroxisomal membrane;GO:0005829 cytosol;GO:1904949 ATPase complex", "go_biological_process": "GO:0043335 protein unfolding;GO:0016558 protein import into peroxisome matrix;GO:0016562 protein import into peroxisome matrix, receptor recycling", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P24004-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P24276-1", "uniprot_id": "SSD1_YEAST", "mass": 139954.0, "length": 1250, "protein_name": "Protein SSD1", "gene_name": "SSD1", "organism": "Yeast", "refseq_name": "mRNA-binding translational repressor SSD1", "refseq_ac": "NP_010579", "gene_names_uniprotkb": "SSD1; CLA1; D9819.4; RLD1; SRK1", "gene_names_refseq": "CLA1; MCS1; RLT1; SRK1; SSD1", "protein_names_uniprotkb": "Protein SSD1; Protein SRK1", "protein_names_refseq": "mRNA-binding translational repressor SSD1", "tax_id": 559292, "disease": "Perlman syndrome (Disease Ontology:DOID:0060476); nephroblastoma (Disease Ontology:DOID:2154)", "pathway": " (sce:YDR293C)", "pathway_count": 1, "publication_count": 27, "publication_id_list": "11875433;14562106;15665377;1645449;17287358;17330950;17563356;18407956;1848673;19684113;19779198;19795423;19823750;19962308;20702584;21126336;21177495;22218487;22814378;23749301;24374639;27821475;30516470;32597660;33481703;33491328;9169867", "class_list": "", "function": "Can suppress the lethality due to deletion of SIT4, and partially the defects due to BCY1 disruption. Is implicated in the control of the cell cycle G1 phase., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 60, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSS2", "ec_number_list": "", "go_molecular_function": "GO:0000900 mRNA regulatory element binding translation repressor activity;GO:0003729 mRNA binding;GO:0042802 identical protein binding;GO:0003730 mRNA 3'-UTR binding;GO:0000175 3'-5'-RNA exonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000932 P-body;GO:0010494 cytoplasmic stress granule;GO:0005933 cellular bud", "go_biological_process": "GO:0051301 cell division;GO:0017148 negative regulation of translation;GO:0006402 mRNA catabolic process;GO:0008298 intracellular mRNA localization;GO:1903450 regulation of G1 to G0 transition", "synthesized_glycan_count": 0, "hit_score": 2.8, "record_id": "P24276-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P24279-1", "uniprot_id": "MCM3_YEAST", "mass": 107518.0, "length": 971, "protein_name": "DNA replication licensing factor MCM3", "gene_name": "MCM3", "organism": "Yeast", "refseq_name": "MCM DNA helicase complex subunit MCM3", "refseq_ac": "NP_010882", "gene_names_uniprotkb": "MCM3; SYGP-ORF23", "gene_names_refseq": "MCM3", "protein_names_uniprotkb": "DNA replication licensing factor MCM3; 3.6.4.12; Minichromosome maintenance protein 3", "protein_names_refseq": "MCM DNA helicase complex subunit MCM3", "tax_id": 559292, "disease": "", "pathway": " (sce:YEL032W); (R-SCE-176187); (R-SCE-68867); (R-SCE-68962); (R-SCE-69052)", "pathway_count": 5, "publication_count": 25, "publication_id_list": "11875433;14562106;15023545;15665377;17287358;17330950;17563356;18407956;18657510;19684113;19779198;19896182;19910535;20702584;21070963;21126336;21177495;2233713;23749301;24374639;30516470;32597660;33481703;33491328;9169868", "class_list": "", "function": "Acts as a component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Once loaded onto DNA, double hexamers can slide on dsDNA in the absence of ATPase activity. Necessary for cell growth., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 30, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D3DLL7", "ec_number_list": "2.7.11.22;2.7.11.1;3.6.4.13;5.6.2.3;3.6.4.10;2.7.7.-;3.6.-.-;5.6.2.4;2.7.7.7;3.6.4.-;5.6.1.4;3.1.11.-;3.6.4.12;3.6.4.6;5.6.2.5;3.6.1.-;2.3.2.27;3.1.-.-;3.4.24.-;3.6.5.-;2.7.4.3;7.2.2.-", "go_molecular_function": "GO:0003688 DNA replication origin binding;GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0005656 nuclear pre-replicative complex;GO:0031261 DNA replication preinitiation complex;GO:0043596 nuclear replication fork;GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication;GO:0006271 DNA strand elongation involved in DNA replication;GO:0031509 subtelomeric heterochromatin formation;GO:0006260 DNA replication;GO:0006270 DNA replication initiation", "synthesized_glycan_count": 0, "hit_score": 2.6, "record_id": "P24279-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P24280-1", "uniprot_id": "SEC14_YEAST", "mass": 34901.0, "length": 304, "protein_name": "SEC14 cytosolic factor", "gene_name": "SEC14", "organism": "Yeast", "refseq_name": "phosphatidylinositol/phosphatidylcholine transfer protein SEC14", "refseq_ac": "NP_013796", "gene_names_uniprotkb": "SEC14; PIT1; YM9582.04", "gene_names_refseq": "PIT1; SEC14", "protein_names_uniprotkb": "SEC14 cytosolic factor; PI/PC TP; Phosphatidylinositol/phosphatidylcholine transfer protein", "protein_names_refseq": "phosphatidylinositol/phosphatidylcholine transfer protein SEC14", "tax_id": 559292, "disease": "breast cancer (Disease Ontology:DOID:1612); esophageal cancer (Disease Ontology:DOID:5041)", "pathway": " (sce:YMR079W)", "pathway_count": 1, "publication_count": 28, "publication_id_list": "10488334;10848624;12869188;14562106;16997918;18407956;19129178;19779198;19795423;19823750;1997207;20702584;21126336;22106047;2215682;23383173;23749301;2407740;24374639;2466847;29307839;32597660;32828847;33481703;33491328;7816798;9169872;9461221", "class_list": "", "function": "Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidylcholine (PC) between membranes in vitro. Essential for viability and secretion (PubMed:2215682, PubMed:2466847). Exchanges its bound phospholipid with phospholipid monomers that reside in membrane bilayers (PubMed:16997918). Regulates specific trans-Golgi export pathways, like transport from endosomes to the trans-Golgi or transport from the plasma membrane to the vacuole at the level of the endosome (PubMed:19129178). Increased membrane curvature and lipid unsaturation levels at the trans-Golgi membrane promotes membrane binding and phospholipid transfer of SEC14. Thus, SEC14 may act at the trans-Golgi membrane to exchange lipids and promote vesicle formation (PubMed:32828847). The phosphatidylcholine-bound form of SEC14 represses the CDP-choline pathway activity by inhibiting CCTase, the rate-determining enzyme of the CDP-choline pathway (PubMed:7816798). PI binding/transfer is dispensable for function in vivo (PubMed:10488334). Required for trafficking and localization of lipid raft proteins to the plasma membrane (PubMed:23383173)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VZQ3", "ec_number_list": "", "go_molecular_function": "GO:0008526 phosphatidylinositol transfer activity;GO:0008525 phosphatidylcholine transporter activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0005829 cytosol", "go_biological_process": "GO:0015914 phospholipid transport;GO:0043001 Golgi to plasma membrane protein transport;GO:0006892 post-Golgi vesicle-mediated transport;GO:0048194 Golgi vesicle budding;GO:0046488 phosphatidylinositol metabolic process", "synthesized_glycan_count": 0, "hit_score": 2.9, "record_id": "P24280-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P24783-1", "uniprot_id": "DBP2_YEAST", "mass": 60999.0, "length": 546, "protein_name": "ATP-dependent RNA helicase DBP2", "gene_name": "DBP2", "organism": "Yeast", "refseq_name": "DEAD-box ATP-dependent RNA helicase DBP2", "refseq_ac": "NP_014287", "gene_names_uniprotkb": "DBP2; N1945", "gene_names_refseq": "DBP2", "protein_names_uniprotkb": "ATP-dependent RNA helicase DBP2; 3.6.4.13; DEAD box protein 2; p68-like protein", "protein_names_refseq": "DEAD-box ATP-dependent RNA helicase DBP2", "tax_id": 559292, "disease": "abdominal obesity-metabolic syndrome (Disease Ontology:DOID:0060611); alcohol use disorder (Disease Ontology:DOID:1574); cancer (Disease Ontology:DOID:162); skin squamous cell carcinoma (Disease Ontology:DOID:3151)", "pathway": " (sce:YNL112W); (R-SCE-3899300); (R-SCE-9018519)", "pathway_count": 3, "publication_count": 29, "publication_id_list": "11585918;14562095;14562106;17287358;17330950;17563356;18407956;1869554;19779198;19795423;19823750;1996094;20702584;21177495;22106047;22679025;23721653;23749301;24374639;24909858;26046779;32597660;33481703;33491328;33856219;7641698;7883168;9090055;9169873", "class_list": "", "function": "ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing (PubMed:11585918, PubMed:7883168). Associates directly with chromatin, correlating with transcriptional activity (PubMed:22679025). Required for assembly of mRNA-binding proteins YRA1, NAB2, and MEX67 onto poly(A)+ RNA (PubMed:23721653)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W169;Q05456", "ec_number_list": "3.6.4.13;5.6.2.3;3.6.4.10;3.6.-.-;5.6.2.4;3.6.4.-;5.6.1.4;3.6.4.12;3.6.4.6;5.6.2.5;3.6.1.-;2.3.2.27;2.1.1.319;3.1.-.-;3.4.24.-;3.6.5.-;2.3.1.48;2.3.2.-;2.3.1.-;2.7.4.3;2.7.11.1;7.2.2.-", "go_molecular_function": "GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0030515 snoRNA binding;GO:0002151 G-quadruplex RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0071042 nuclear polyadenylation-dependent mRNA catabolic process;GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006364 rRNA processing;GO:0000380 alternative mRNA splicing, via spliceosome;GO:0006369 termination of RNA polymerase II transcription", "synthesized_glycan_count": 0, "hit_score": 3.0, "record_id": "P24783-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P24813-1", "uniprot_id": "AP2_YEAST", "mass": 45752.0, "length": 409, "protein_name": "AP-1-like transcription factor YAP2", "gene_name": "CAD1", "organism": "Yeast", "refseq_name": "Cad1p", "refseq_ac": "NP_010711", "gene_names_uniprotkb": "CAD1; D9461.12; YAP2", "gene_names_refseq": "CAD1; YAP2", "protein_names_uniprotkb": "AP-1-like transcription factor YAP2; Cadmium resistance protein 1; Transcription factor CAD1", "protein_names_refseq": "Cad1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR423C)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "10357825;12006656;14562095;14562106;1514324;15341652;17187783;20145245;24374639;33481703;33491328;7565103;8107671;8226890;8360174;9130715;9169867;9372930", "class_list": "", "function": "Transcription activator involved in oxidative stress response and cadmium resistance. Regulates the transcription of genes overrepresented for the function of stabilizing proteins including the inducible Hsp90-family protein HSP82. Preferentially binds to promoters with the core binding site 5'-TTA[CG]TAA-3'. Activity of the transcription factor is controlled through oxidation of specific cysteine residues resulting in the alteration of its subcellular location. Activation by alkyl hydroperoxides or cadmium induces nuclear accumulation and as a result CAD1/YAP2 transcriptional activity., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VT53;Q02259", "ec_number_list": "", "go_molecular_function": "GO:0000976 transcription cis-regulatory region binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0090575 RNA polymerase II transcription regulator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0046686 response to cadmium ion;GO:0033554 cellular response to stress", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P24813-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P24814-1", "uniprot_id": "GRR1_YEAST", "mass": 132734.0, "length": 1151, "protein_name": "SCF E3 ubiquitin ligase complex F-box protein GRR1", "gene_name": "GRR1", "organism": "Yeast", "refseq_name": "SCF ubiquitin ligase complex subunit GRR1", "refseq_ac": "NP_012623", "gene_names_uniprotkb": "GRR1; CAT80; COT2; J1885", "gene_names_refseq": "CAT80; COT2; GRR1; RMR3; SDC1; SSU2", "protein_names_uniprotkb": "SCF E3 ubiquitin ligase complex F-box protein GRR1; F-box and leucine-rich repeat protein GRR1; F-box/LRR-repeat protein GRR1", "protein_names_refseq": "SCF ubiquitin ligase complex subunit GRR1", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR090C)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "10213692;14747994;17563356;18407956;1922034;20489023;23749301;24374639;32597660;33229814;33481703;33491328;7883165;8641269;8840504;9736614", "class_list": "", "function": "Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and directs ubiquitination of phosphorylated CLN1, CLN2 and GIC2. Probably constitutes the primary response element required for the generation or interpretation of the signal that induces glucose repression., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VWQ8", "ec_number_list": "", "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016020 membrane;GO:0019005 SCF ubiquitin ligase complex;GO:0000142 cellular bud neck contractile ring", "go_biological_process": "GO:0006006 glucose metabolic process;GO:0034599 cellular response to oxidative stress;GO:0000082 G1/S transition of mitotic cell cycle;GO:0000209 protein polyubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P24814-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P24867-1", "uniprot_id": "PCL1_YEAST", "mass": 32095.0, "length": 279, "protein_name": "PHO85 cyclin-1", "gene_name": "PCL1", "organism": "Yeast", "refseq_name": "Pcl1p", "refseq_ac": "NP_014110", "gene_names_uniprotkb": "PCL1; HCS26; N0536", "gene_names_refseq": "HCS26; PCL1", "protein_names_uniprotkb": "PHO85 cyclin-1; Cyclin HCS26; G1/S-specific cyclin PCL1", "protein_names_refseq": "Pcl1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL289W)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "14562106;14688790;15082539;15598647;1832336;20489023;23264631;23749301;24374639;32597660;33481703;33491328;7973730;9032248;9169873;9725902", "class_list": "", "function": "G1/S-specific cyclin partner of the cyclin-dependent kinase (CDK) PHO85. Essential for the control of the cell cycle at the G1/S (start) transition. The PCL1-PHO85 cyclin-CDK holoenzyme is involved in phosphorylation of the CDK inhibitor (CKI) SIC1, which is required for its ubiquitination and degradation, releasing repression of b-type cyclins and promoting exit from mitosis. Together with cyclin PCL2, positively controls degradation of sphingoid long chain base kinase LCB4. PCL1-PHO85 phosphorylates LCB4, which is required for its ubiquitination and degradation. PCL1-PHO85 also phosphorylates HMS1, NCP1 and NPA3, which may all have a role in mitotic exit., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W0Q4", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding;GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000307 cyclin-dependent protein kinase holoenzyme complex;GO:0000131 incipient cellular bud site;GO:0005935 cellular bud neck", "go_biological_process": "GO:0032878 regulation of establishment or maintenance of cell polarity;GO:0001676 long-chain fatty acid metabolic process;GO:0051301 cell division;GO:0000082 G1/S transition of mitotic cell cycle;GO:0016239 positive regulation of macroautophagy", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P24867-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P24868-1", "uniprot_id": "CG21_YEAST", "mass": 54871.0, "length": 471, "protein_name": "G2/mitotic-specific cyclin-1", "gene_name": "CLB1", "organism": "Yeast", "refseq_name": "B-type cyclin CLB1", "refseq_ac": "NP_011622", "gene_names_uniprotkb": "CLB1; G5967; SCB1", "gene_names_refseq": "CLB1; SCB1", "protein_names_uniprotkb": "G2/mitotic-specific cyclin-1", "protein_names_refseq": "B-type cyclin CLB1", "tax_id": 559292, "disease": "prostate cancer (Disease Ontology:DOID:10283); breast cancer (Disease Ontology:DOID:1612); ovary epithelial cancer (Disease Ontology:DOID:2152); prostate adenocarcinoma (Disease Ontology:DOID:2526); endometrial carcinoma (Disease Ontology:DOID:2871); cervical cancer (Disease Ontology:DOID:4362); renal cell carcinoma (Disease Ontology:DOID:4450); in situ carcinoma (Disease Ontology:DOID:8719)", "pathway": " (sce:YGR108W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562106;1849457;1849458;23749301;24374639;33481703;33491328;9169869", "class_list": "", "function": "Essential for the control of the cell cycle at the G2/M (mitosis) transition. Interacts with the CDC2 protein kinase to form MPF. G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUN9", "ec_number_list": "", "go_molecular_function": "GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005815 microtubule organizing center;GO:0000307 cyclin-dependent protein kinase holoenzyme complex", "go_biological_process": "GO:0051301 cell division;GO:0000086 G2/M transition of mitotic cell cycle;GO:0000082 G1/S transition of mitotic cell cycle;GO:0001932 regulation of protein phosphorylation;GO:0007052 mitotic spindle organization", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P24868-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P24869-1", "uniprot_id": "CG22_YEAST", "mass": 56247.0, "length": 491, "protein_name": "G2/mitotic-specific cyclin-2", "gene_name": "CLB2", "organism": "Yeast", "refseq_name": "B-type cyclin CLB2", "refseq_ac": "NP_015444", "gene_names_uniprotkb": "CLB2; P9642.6", "gene_names_refseq": "CLB2", "protein_names_uniprotkb": "G2/mitotic-specific cyclin-2", "protein_names_refseq": "B-type cyclin CLB2", "tax_id": 559292, "disease": "prostate cancer (Disease Ontology:DOID:10283); breast cancer (Disease Ontology:DOID:1612); ovary epithelial cancer (Disease Ontology:DOID:2152); prostate adenocarcinoma (Disease Ontology:DOID:2526); endometrial carcinoma (Disease Ontology:DOID:2871); cervical cancer (Disease Ontology:DOID:4362); renal cell carcinoma (Disease Ontology:DOID:4450); in situ carcinoma (Disease Ontology:DOID:8719)", "pathway": " (sce:YPR119W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "1427070;14562106;1849457;19779198;22814378;24374639;33481703;33491328;7622566;9169875", "class_list": "", "function": "Essential for the control of the cell cycle at the G2/M (mitosis) transition. Interacts with the CDC2 protein kinase to form MPF. G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W4B8", "ec_number_list": "", "go_molecular_function": "GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005819 spindle;GO:0005815 microtubule organizing center;GO:0000307 cyclin-dependent protein kinase holoenzyme complex", "go_biological_process": "GO:0051301 cell division;GO:0000086 G2/M transition of mitotic cell cycle;GO:0006974 DNA damage response;GO:0000082 G1/S transition of mitotic cell cycle;GO:0007089 traversing start control point of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P24869-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P24870-1", "uniprot_id": "CG23_YEAST", "mass": 49476.0, "length": 427, "protein_name": "G2/mitotic-specific cyclin-3", "gene_name": "CLB3", "organism": "Yeast", "refseq_name": "B-type cyclin CLB3", "refseq_ac": "NP_010126", "gene_names_uniprotkb": "CLB3; D1539", "gene_names_refseq": "CLB3", "protein_names_uniprotkb": "G2/mitotic-specific cyclin-3", "protein_names_refseq": "B-type cyclin CLB3", "tax_id": 559292, "disease": "prostate cancer (Disease Ontology:DOID:10283); breast cancer (Disease Ontology:DOID:1612); ovary epithelial cancer (Disease Ontology:DOID:2152); prostate adenocarcinoma (Disease Ontology:DOID:2526); endometrial carcinoma (Disease Ontology:DOID:2871); cervical cancer (Disease Ontology:DOID:4362); renal cell carcinoma (Disease Ontology:DOID:4450); in situ carcinoma (Disease Ontology:DOID:8719)", "pathway": " (sce:YDL155W)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "1387566;1427070;14562106;17322287;18407956;1849457;19779198;20489023;20702584;22031224;23749301;24374639;33481703;33491328;8972581;9169867", "class_list": "", "function": "Essential for the control of the cell cycle at the G2/M (mitosis) transition. Interacts with the CDC2 protein kinase to form MPF. G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRJ5", "ec_number_list": "", "go_molecular_function": "GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005811 lipid droplet;GO:0005815 microtubule organizing center;GO:0000307 cyclin-dependent protein kinase holoenzyme complex", "go_biological_process": "GO:0051301 cell division;GO:0000086 G2/M transition of mitotic cell cycle;GO:0000082 G1/S transition of mitotic cell cycle;GO:0001932 regulation of protein phosphorylation;GO:1901673 regulation of mitotic spindle assembly", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P24870-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25042-1", "uniprot_id": "ROX1_YEAST", "mass": 41838.0, "length": 368, "protein_name": "Repressor ROX1", "gene_name": "ROX1", "organism": "Yeast", "refseq_name": "Rox1p", "refseq_ac": "NP_015390", "gene_names_uniprotkb": "ROX1; YP9499.20", "gene_names_refseq": "REO1; ROX1", "protein_names_uniprotkb": "Repressor ROX1; Heme-dependent repression factor; Hypoxic function repressor", "protein_names_refseq": "Rox1p", "tax_id": 559292, "disease": "intestinal cancer (Disease Ontology:DOID:10155)", "pathway": " (sce:YPR065W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "14562106;18407956;19779198;21177495;24374639;32597660;33481703;33491328;8413209;8600445;9169875", "class_list": "", "function": "Transcription factor that represses the expression of HEM13, COX5B, ANB1, CYC7 or AAC3 (hypoxic function). Binds to the DNA sequence 5'-RRRTAACAAGAG-3'., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W469", "ec_number_list": "", "go_molecular_function": "GO:0008301 DNA binding, bending;GO:0003714 transcription corepressor activity;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000987 cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0071472 cellular response to salt stress", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P25042-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25043-1", "uniprot_id": "PSB2_YEAST", "mass": 28268.0, "length": 261, "protein_name": "Proteasome subunit beta type-2", "gene_name": "PUP1", "organism": "Yeast", "refseq_name": "proteasome core particle subunit beta 2", "refseq_ac": "NP_014800", "gene_names_uniprotkb": "PUP1", "gene_names_refseq": "PUP1", "protein_names_uniprotkb": "Proteasome subunit beta type-2; 3.4.25.1; Macropain subunit PUP1; Multicatalytic endopeptidase complex subunit PUP1; Proteasome component PUP1; Proteinase YSCE subunit PUP1", "protein_names_refseq": "proteasome core particle subunit beta 2", "tax_id": 559292, "disease": "Omenn syndrome (Disease Ontology:DOID:0060010); proteosome-associated autoinflammatory syndrome 5 (Disease Ontology:DOID:0060919); immunodeficiency 121 (Disease Ontology:DOID:0061087)", "pathway": " (sce:YOR157C); (R-SCE-1236974); (R-SCE-1236978); (R-SCE-5668541); (R-SCE-5689880); (R-SCE-6798695); (R-SCE-9907900); (R-SCE-9912633)", "pathway_count": 8, "publication_count": 16, "publication_id_list": "11062564;11081519;14562106;16531229;16608349;16793518;1923775;20227375;22814378;22927375;24374639;33481703;33491328;9046089;9087403;9169874", "class_list": "", "function": "The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W2L4", "ec_number_list": "2.7.1.40;5.4.2.11;2.7.1.1;4.2.1.24;3.6.4.13;2.4.1.1;3.4.23.25;3.6.4.10;5.3.1.9;5.1.3.-;5.2.1.8;1.11.1.6;3.5.4.6;2.7.1.11;2.7.1.2;1.1.1.42;3.4.25.1;3.6.4.6;3.6.5.-;2.7.11.24;3.6.4.12;5.4.2.2;1.11.1.24;2.7.4.6;2.4.1.186;1.1.1.205;2.7.1.35;3.4.19.12;2.4.2.7;2.7.11.1;5.4.2.7;2.3.2.26;2.7.11.23;2.4.2.1;2.7.1.59;3.5.4.5;3.4.11.-;3.3.2.10", "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0004298 threonine-type endopeptidase activity", "go_cellular_component": "GO:0034515 proteasome storage granule;GO:0019774 proteasome core complex, beta-subunit complex;GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0010499 proteasomal ubiquitin-independent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P25043-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25044-1", "uniprot_id": "PTP1_YEAST", "mass": 38868.0, "length": 335, "protein_name": "Tyrosine-protein phosphatase 1", "gene_name": "PTP1", "organism": "Yeast", "refseq_name": "tyrosine protein phosphatase PTP1", "refseq_ac": "NP_010051", "gene_names_uniprotkb": "PTP1", "gene_names_refseq": "PTP1", "protein_names_uniprotkb": "Tyrosine-protein phosphatase 1; 3.1.3.48; PTPase 1; Protein-tyrosine phosphatase 1", "protein_names_refseq": "tyrosine protein phosphatase PTP1", "tax_id": 559292, "disease": "restless legs syndrome (Disease Ontology:DOID:0050425); severe combined immunodeficiency 105 (Disease Ontology:DOID:0061074); Graves ophthalmopathy (Disease Ontology:DOID:0081120); graft-versus-host disease (Disease Ontology:DOID:0081267); chronic lymphocytic leukemia (Disease Ontology:DOID:1040); pre-eclampsia (Disease Ontology:DOID:10591); hypertension (Disease Ontology:DOID:10763); essential hypertension (Disease Ontology:DOID:10825); anogenital venereal wart (Disease Ontology:DOID:11168); vitiligo (Disease Ontology:DOID:12306); Graves' disease (Disease Ontology:DOID:12361); Sjogren's syndrome (Disease Ontology:DOID:12894); proliferative diabetic retinopathy (Disease Ontology:DOID:13207); Behcet's disease (Disease Ontology:DOID:13241); temporal arteritis (Disease Ontology:DOID:13375); Addison's disease (Disease Ontology:DOID:13774); hypothyroidism (Disease Ontology:DOID:1459); urticaria (Disease Ontology:DOID:1555); thrombocytopenia (Disease Ontology:DOID:1588); hyperinsulinism (Disease Ontology:DOID:2018); transient cerebral ischemia (Disease Ontology:DOID:224); multiple sclerosis (Disease Ontology:DOID:2377); endometriosis (Disease Ontology:DOID:289); pulmonary tuberculosis (Disease Ontology:DOID:2957); coronary artery disease (Disease Ontology:DOID:3393); pancreatic ductal adenocarcinoma (Disease Ontology:DOID:3498); gastric adenocarcinoma (Disease Ontology:DOID:3717); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung squamous cell carcinoma (Disease Ontology:DOID:3907); lung adenocarcinoma (Disease Ontology:DOID:3910); systemic scleroderma (Disease Ontology:DOID:418); cervical cancer (Disease Ontology:DOID:4362); myasthenia gravis (Disease Ontology:DOID:437); severe combined immunodeficiency (Disease Ontology:DOID:627); systemic juvenile rheumatoid arthritis (Disease Ontology:DOID:676); rheumatoid arthritis (Disease Ontology:DOID:7148); autoimmune thyroiditis (Disease Ontology:DOID:7188); retinal degeneration (Disease Ontology:DOID:8466); Crohn's disease (Disease Ontology:DOID:8778); psoriasis (Disease Ontology:DOID:8893); autoimmune thrombocytopenic purpura (Disease Ontology:DOID:8924); psoriatic arthritis (Disease Ontology:DOID:9008); systemic lupus erythematosus (Disease Ontology:DOID:9074); colorectal cancer (Disease Ontology:DOID:9256); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352); type 1 diabetes mellitus (Disease Ontology:DOID:9744); Meniere's disease (Disease Ontology:DOID:9849); alopecia areata (Disease Ontology:DOID:986); obesity (Disease Ontology:DOID:9970)", "pathway": " (sce:YDL230W); (R-SCE-6798695)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "10480872;14562106;1649172;24374639;33491328;9169867", "class_list": "", "function": "Is not required for vegetative growth., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 50, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRC6", "ec_number_list": "3.6.5.2;3.1.3.48;2.3.1.51;2.3.1.23;2.3.1.n7;3.1.4.4;3.1.3.16;7.6.2.1;3.1.3.2;3.4.11.-;1.2.1.3;1.2.1.64", "go_molecular_function": "GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0007165 signal transduction;GO:0001403 invasive growth in response to glucose limitation;GO:0007124 pseudohyphal growth", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P25044-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25045-1", "uniprot_id": "SPTC1_YEAST", "mass": 62207.0, "length": 558, "protein_name": "Serine palmitoyltransferase 1", "gene_name": "LCB1", "organism": "Yeast", "refseq_name": "serine C-palmitoyltransferase LCB1", "refseq_ac": "NP_014025", "gene_names_uniprotkb": "LCB1; END8; TSC2", "gene_names_refseq": "END8; LCB1; TSC2", "protein_names_uniprotkb": "Serine palmitoyltransferase 1; 2.3.1.50; Long chain base biosynthesis protein 1; SPT 1; SPT1", "protein_names_refseq": "serine C-palmitoyltransferase LCB1", "tax_id": 559292, "disease": "hereditary sensory and autonomic neuropathy (Disease Ontology:DOID:0050548); hereditary sensory and autonomic neuropathy type 1A (Disease Ontology:DOID:0070152); hereditary sensory and autonomic neuropathy type 1 (Disease Ontology:DOID:0070162); juvenile amyotrophic lateral sclerosis type 27 (Disease Ontology:DOID:0081381); amyotrophic lateral sclerosis (Disease Ontology:DOID:332)", "pathway": " (sce:YMR296C)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "10713067;11781309;14562095;14562106;15485854;17322287;17330950;19795423;19823750;20182505;2066332;21177495;24374639;33491328;8058731;9169872", "class_list": "", "function": "Component of serine palmitoyltransferase (SPT), which catalyzes the committed step in the synthesis of sphingolipids, the condensation of serine with palmitoyl CoA to form the long chain base 3-ketosphinganine., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 13, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0C3", "ec_number_list": "2.3.1.50", "go_molecular_function": "GO:0004758 serine C-palmitoyltransferase activity;GO:0030170 pyridoxal phosphate binding", "go_cellular_component": "GO:0017059 serine palmitoyltransferase complex;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0046513 ceramide biosynthetic process;GO:0030148 sphingolipid biosynthetic process;GO:0046512 sphingosine biosynthetic process;GO:0090156 intracellular sphingolipid homeostasis", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P25045-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25046-1", "uniprot_id": "MED19_YEAST", "mass": 24857.0, "length": 220, "protein_name": "Mediator of RNA polymerase II transcription subunit 19", "gene_name": "ROX3", "organism": "Yeast", "refseq_name": "Rox3p", "refseq_ac": "NP_009459", "gene_names_uniprotkb": "ROX3; MED19; NUT3; SSN7; YBL0837", "gene_names_refseq": "MED19; NUT3; RMR1; ROX3; SSN7; SSX2", "protein_names_uniprotkb": "Mediator of RNA polymerase II transcription subunit 19; Hypoxic gene repressor protein 3; Mediator complex subunit 19; Negative regulator of URS2 protein 3; SNF1 suppressor protein 7", "protein_names_refseq": "Rox3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YBL093C)", "pathway_count": 1, "publication_count": 21, "publication_id_list": "11555651;12191485;14562095;14562106;15175151;15477388;16002404;16076843;16263706;1656237;16630888;17192271;17322287;21177495;23749301;24374639;33481703;33491328;7502586;7813418;8995225", "class_list": "", "function": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. The Mediator complex unfolds to an extended conformation and partially surrounds RNA polymerase II, specifically interacting with the unphosphorylated form of the C-terminal domain (CTD) of RNA polymerase II. The Mediator complex dissociates from the RNA polymerase II holoenzyme and stays at the promoter when transcriptional elongation begins., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VPR0", "ec_number_list": "", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016592 mediator complex;GO:0070847 core mediator complex", "go_biological_process": "GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0001113 transcription open complex formation at RNA polymerase II promoter", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P25046-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25087-1", "uniprot_id": "ERG6_YEAST", "mass": 43431.0, "length": 383, "protein_name": "Sterol 24-C-methyltransferase ERG6", "gene_name": "ERG6", "organism": "Yeast", "refseq_name": "sterol 24-C-methyltransferase", "refseq_ac": "NP_013706", "gene_names_uniprotkb": "ERG6; ISE1; LIS1; SED6; YM9571.10C", "gene_names_refseq": "ERG6; ISE1; LIS1; SED6; VID1", "protein_names_uniprotkb": "Sterol 24-C-methyltransferase ERG6; 2.1.1.41; Delta(24)-sterol C-methyltransferase ERG6; Ergosterol biosynthetic protein 6; SCMT", "protein_names_refseq": "sterol 24-C-methyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YML008C)", "pathway_count": 1, "publication_count": 24, "publication_id_list": "11875433;14562106;15522820;15995173;18407956;19779198;2060792;20702584;21126336;22218487;23749301;24374639;29773647;32597660;32679672;33481703;33491328;34965436;37604855;6363386;8038180;8203167;9169872;9298649", "class_list": "", "function": "Sterol 24-C-methyltransferase; part of the third module of ergosterol biosynthesis pathway that includes the late steps of the pathway (PubMed:6363386). ERG6 catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol (PubMed:6363386). The third module or late pathway involves the ergosterol synthesis itself through consecutive reactions that mainly occur in the endoplasmic reticulum (ER) membrane. Firstly, the squalene synthase ERG9 catalyzes the condensation of 2 farnesyl pyrophosphate moieties to form squalene, which is the precursor of all steroids. Squalene synthase is crucial for balancing the incorporation of farnesyl diphosphate (FPP) into sterol and nonsterol isoprene synthesis. Secondly, the squalene epoxidase ERG1 catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, which is considered to be a rate-limiting enzyme in steroid biosynthesis. Then, the lanosterol synthase ERG7 catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol core. In the next steps, lanosterol is transformed to zymosterol through a complex process involving various demethylation, reduction and desaturation reactions. The lanosterol 14-alpha-demethylase ERG11 (also known as CYP51) catalyzes C14-demethylation of lanosterol to produce 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol, which is critical for ergosterol biosynthesis. The C-14 reductase ERG24 reduces the C14=C15 double bond of 4,4-dimethyl-cholesta-8,14,24-trienol to produce 4,4-dimethyl-cholesta-8,24-dienol. 4,4-dimethyl-cholesta-8,24-dienol is substrate of the C-4 demethylation complex ERG25-ERG26-ERG27 in which ERG25 catalyzes the three-step monooxygenation required for the demethylation of 4,4-dimethyl and 4alpha-methylsterols, ERG26 catalyzes the oxidative decarboxylation that results in a reduction of the 3-beta-hydroxy group at the C-3 carbon to an oxo group, and ERG27 is responsible for the reduction of the keto group on the C-3. ERG28 has a role as a scaffold to help anchor ERG25, ERG26 and ERG27 to the endoplasmic reticulum and ERG29 regulates the activity of the iron-containing C4-methylsterol oxidase ERG25. Then, the sterol 24-C-methyltransferase ERG6 catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. The C-8 sterol isomerase ERG2 catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols and thus converts fecosterol to episterol. The sterol-C5-desaturase ERG3 then catalyzes the introduction of a C-5 double bond in the B ring to produce 5-dehydroepisterol. The C-22 sterol desaturase ERG5 further converts 5-dehydroepisterol into ergosta-5,7,22,24(28)-tetraen-3beta-ol by forming the C-22(23) double bond in the sterol side chain. Finally, ergosta-5,7,22,24(28)-tetraen-3beta-ol is substrate of the C-24(28) sterol reductase ERG4 to produce ergosterol (PubMed:32679672)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 16, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZG6", "ec_number_list": "2.1.1.41", "go_molecular_function": "GO:0042802 identical protein binding;GO:0003838 sterol 24-C-methyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0005783 endoplasmic reticulum;GO:0005811 lipid droplet", "go_biological_process": "GO:0006696 ergosterol biosynthetic process;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "P25087-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25296-1", "uniprot_id": "CANB_YEAST", "mass": 19639.0, "length": 175, "protein_name": "Calcineurin subunit B", "gene_name": "CNB1", "organism": "Yeast", "refseq_name": "calcineurin regulatory subunit B", "refseq_ac": "NP_012731", "gene_names_uniprotkb": "CNB1; YCN2; YCNB", "gene_names_refseq": "CNB1; CRV1; YCN2", "protein_names_uniprotkb": "Calcineurin subunit B; Calcineurin regulatory subunit; Protein phosphatase 2B regulatory subunit", "protein_names_refseq": "calcineurin regulatory subunit B", "tax_id": 559292, "disease": "traumatic brain injury (Disease Ontology:DOID:0081292); Alzheimer's disease (Disease Ontology:DOID:10652); dilated cardiomyopathy (Disease Ontology:DOID:12930); schizophrenia (Disease Ontology:DOID:5419)", "pathway": " (sce:YKL190W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "1321337;1659397;23749301;24374639;33481703;33491328;8154185;8196765;8394042", "class_list": "", "function": "Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VX10", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0019902 phosphatase binding;GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity", "go_cellular_component": "GO:0005955 calcineurin complex", "go_biological_process": "GO:0097720 calcineurin-mediated signaling;GO:0045893 positive regulation of DNA-templated transcription;GO:0022604 regulation of cell morphogenesis;GO:0006873 intracellular monoatomic ion homeostasis;GO:0071444 cellular response to pheromone", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P25296-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25297-1", "uniprot_id": "PHO84_YEAST", "mass": 64382.0, "length": 587, "protein_name": "Inorganic phosphate transporter PHO84", "gene_name": "PHO84", "organism": "Yeast", "refseq_name": "phosphate transporter PHO84", "refseq_ac": "NP_013583", "gene_names_uniprotkb": "PHO84; YM7056.03C", "gene_names_refseq": "PHO84", "protein_names_uniprotkb": "Inorganic phosphate transporter PHO84", "protein_names_refseq": "phosphate transporter PHO84", "tax_id": 559292, "disease": "systemic primary carnitine deficiency disease (Disease Ontology:DOID:14365)", "pathway": " (sce:YML123C)", "pathway_count": 1, "publication_count": 27, "publication_id_list": "10518922;11573939;11779791;12581367;12872131;12923174;14562106;17330950;17563356;18407956;19348508;19684113;19779198;20133652;2038328;20702584;21177495;22106047;22218487;22587366;24374639;27875295;32597660;33481703;33491328;7851439;9169872", "class_list": "", "function": "Proton-coupled high-affinity transporter for external inorganic phosphate (PubMed:10518922, PubMed:11573939, PubMed:11779791, PubMed:19348508, PubMed:20133652, PubMed:2038328, PubMed:7851439). Acts as a transceptor, a membrane protein that in addition to its transporter activity also possesses receptor-like signaling activity; mediates activation of the protein kinase A (PKA) pathway targets during growth induction, triggered by phosphate addition to cells growth-arrested due to previous phosphate starvation (PubMed:12581367, PubMed:20133652, PubMed:22587366). Is not an essential protein, since constitutive, low affinity phosphate transporters exist in yeast (PubMed:11779791, PubMed:12581367). Can function as a low affinity metal transporter that transports manganese, zinc, cobalt and copper (PubMed:12923174). Plays a role in manganese homeostasis predominantly under manganese surplus conditions (PubMed:12923174)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 18, "reported_mutagensis": 37, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0G2", "ec_number_list": "", "go_molecular_function": "GO:0005315 phosphate transmembrane transporter activity;GO:0005384 manganese ion transmembrane transporter activity;GO:0097079 selenite:proton symporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0006817 phosphate ion transport;GO:0006828 manganese ion transport;GO:0006797 polyphosphate metabolic process;GO:0097080 plasma membrane selenite transport", "synthesized_glycan_count": 0, "hit_score": 2.8, "record_id": "P25297-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25298-1", "uniprot_id": "RNA14_YEAST", "mass": 79960.0, "length": 677, "protein_name": "mRNA 3'-end-processing protein RNA14", "gene_name": "RNA14", "organism": "Yeast", "refseq_name": "cleavage polyadenylation factor subunit RNA14", "refseq_ac": "NP_013777", "gene_names_uniprotkb": "RNA14; YM9796.14", "gene_names_refseq": "RNA14", "protein_names_uniprotkb": "mRNA 3'-end-processing protein RNA14", "protein_names_refseq": "cleavage polyadenylation factor subunit RNA14", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR061W)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10619842;11344258;12727883;14562106;1674817;19795423;19823750;21177495;24374639;33491328;7992054;8900210;9169872;9223284", "class_list": "", "function": "Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with the cleavage factor NAB4/CFIB and the cleavage and polyadenylation factor (CPF) complex., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZN5", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0005848 mRNA cleavage stimulating factor complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0072423 response to DNA damage checkpoint signaling;GO:0031124 mRNA 3'-end processing;GO:0031123 RNA 3'-end processing", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P25298-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25299-1", "uniprot_id": "RNA15_YEAST", "mass": 32791.0, "length": 296, "protein_name": "mRNA 3'-end-processing protein RNA15", "gene_name": "RNA15", "organism": "Yeast", "refseq_name": "Rna15p", "refseq_ac": "NP_011471", "gene_names_uniprotkb": "RNA15", "gene_names_refseq": "RNA15", "protein_names_uniprotkb": "mRNA 3'-end-processing protein RNA15", "protein_names_refseq": "Rna15p", "tax_id": 559292, "disease": "non-syndromic X-linked intellectual disability (Disease Ontology:DOID:0050776)", "pathway": " (sce:YGL044C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "11344258;11689695;14562106;1674817;23749301;24374639;33481703;33491328;7992054;8900210;9169869;9199303;9234674", "class_list": "", "function": "RNA-binding component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with the cleavage factor NAB4/CFIB and the cleavage and polyadenylation factor (CPF) complex. Binds to A-rich RNA sequence elements., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VU95", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0003729 mRNA binding", "go_cellular_component": "GO:0005847 mRNA cleavage and polyadenylation specificity factor complex;GO:0005848 mRNA cleavage stimulating factor complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0031124 mRNA 3'-end processing", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P25299-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25300-1", "uniprot_id": "BUD5_YEAST", "mass": 75046.0, "length": 642, "protein_name": "Bud site selection protein 5", "gene_name": "BUD5", "organism": "Yeast", "refseq_name": "Ras family guanine nucleotide exchange factor BUD5", "refseq_ac": "NP_009967", "gene_names_uniprotkb": "BUD5; YCR38C; YCR526", "gene_names_refseq": "BUD5", "protein_names_uniprotkb": "Bud site selection protein 5", "protein_names_refseq": "Ras family guanine nucleotide exchange factor BUD5", "tax_id": 559292, "disease": "nicotine dependence (Disease Ontology:DOID:0050742); autistic disorder (Disease Ontology:DOID:12849); congestive heart failure (Disease Ontology:DOID:6000)", "pathway": " (sce:YCR038C); (R-SCE-354192); (R-SCE-392517)", "pathway_count": 3, "publication_count": 15, "publication_id_list": "11313501;11378394;11589573;12176366;14562095;14562106;1574125;1789011;1905981;1905982;1964349;24374639;33481703;33491328;8234337", "class_list": "", "function": "GDP-GTP exchange factor (GEF) for the small GTPase BUD1/RSR1. Regulates the activity of BUD1 together with BUD2 which is a GTPase-activating protein (GAP) of BUD1. Required to produce both the axial and bipolar patterns of bud site selection. Determines the orientation of division axis. Overexpression can suppress mutations in PRP20 which is the GEF for GSP1. May be a cytoplasmic GEF for GSP1. Might also act on the Ras-like protein CDC42. Appears to bind to Ras proteins but not to activate them., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VR48;Q06729", "ec_number_list": "", "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0000131 incipient cellular bud site;GO:0005935 cellular bud neck", "go_biological_process": "GO:0007265 Ras protein signal transduction;GO:0007120 axial cellular bud site selection;GO:0007121 bipolar cellular bud site selection", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P25300-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25301-1", "uniprot_id": "RAD57_YEAST", "mass": 52247.0, "length": 460, "protein_name": "DNA repair protein RAD57", "gene_name": "RAD57", "organism": "Yeast", "refseq_name": "putative DNA-dependent ATPase RAD57", "refseq_ac": "NP_010287", "gene_names_uniprotkb": "RAD57; YD8119.10", "gene_names_refseq": "RAD57", "protein_names_uniprotkb": "DNA repair protein RAD57", "protein_names_refseq": "putative DNA-dependent ATPase RAD57", "tax_id": 559292, "disease": "brain glioma (Disease Ontology:DOID:0060108); hypertension (Disease Ontology:DOID:10763); breast cancer (Disease Ontology:DOID:1612); pancreatic cancer (Disease Ontology:DOID:1793); high grade glioma (Disease Ontology:DOID:3070); coronary artery disease (Disease Ontology:DOID:3393); meningioma (Disease Ontology:DOID:3565); central nervous system cancer (Disease Ontology:DOID:3620); myocardial infarction (Disease Ontology:DOID:5844); familial melanoma (Disease Ontology:DOID:6846); multiple myeloma (Disease Ontology:DOID:9538)", "pathway": " (sce:YDR004W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562106;1937004;21126336;24374639;33491328;9169867", "class_list": "", "function": "Participates in the repair of X-ray-induced damage to DNA and in meiosis. It may act in part by stabilizing a repair complex of other RAD genes., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 11, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRZ2", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0003690 double-stranded DNA binding;GO:0003697 single-stranded DNA binding;GO:0008094 ATP-dependent activity, acting on DNA;GO:0000150 DNA strand exchange activity", "go_cellular_component": "GO:0033065 Rad51C-XRCC3 complex", "go_biological_process": "GO:0006312 mitotic recombination;GO:0000707 meiotic DNA recombinase assembly;GO:0006302 double-strand break repair;GO:0000730 DNA recombinase assembly;GO:0042148 DNA strand invasion", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P25301-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25303-1", "uniprot_id": "SCJ1_YEAST", "mass": 41543.0, "length": 377, "protein_name": "DnaJ-related protein SCJ1", "gene_name": "SCJ1", "organism": "Yeast", "refseq_name": "Scj1p", "refseq_ac": "NP_013941", "gene_names_uniprotkb": "SCJ1; YM8261.08", "gene_names_refseq": "SCJ1", "protein_names_uniprotkb": "DnaJ-related protein SCJ1; J protein SCJ1", "protein_names_refseq": "Scj1p", "tax_id": 559292, "disease": "polycystic kidney disease 6 (Disease Ontology:DOID:0060951)", "pathway": " (sce:YMR214W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "11381090;12748633;14562106;2000136;24374639;7744969;9169872;9817751", "class_list": "", "function": "Regulates protein folding in the endoplasmic reticulum lumen. Probably acts as a J-protein for the Hsp70-type chaperone KAR2 by stimulating its ATP-dependent reaction cycle and initiating folding reactions. Also involved in the endoplasmic reticulum-associated degradation (ERAD) process. Cooperates with KAR2 and another J-protein JEM1 to facilitate the export of ERAD substrates to the cytoplasm by maintaining them in a translocation-competent state and preventing their aggregation in the endoplasmic reticulum lumen., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W039", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0051082 unfolded protein binding;GO:0051087 protein-folding chaperone binding;GO:0001671 ATPase activator activity;GO:0030544 Hsp70 protein binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005788 endoplasmic reticulum lumen", "go_biological_process": "GO:0015031 protein transport;GO:0036503 ERAD pathway;GO:0006986 response to unfolded protein;GO:0034975 protein folding in endoplasmic reticulum", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P25303-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25333-1", "uniprot_id": "HAL4_YEAST", "mass": 66666.0, "length": 603, "protein_name": "Serine/threonine-protein kinase HAL4/SAT4", "gene_name": "SAT4", "organism": "Yeast", "refseq_name": "serine/threonine protein kinase SAT4", "refseq_ac": "NP_009934", "gene_names_uniprotkb": "SAT4; HAL4; YCR046; YCR101; YCR8W", "gene_names_refseq": "HAL4; SAT4", "protein_names_uniprotkb": "Serine/threonine-protein kinase HAL4/SAT4; 2.7.11.1; Halotolerance protein 4", "protein_names_refseq": "serine/threonine protein kinase SAT4", "tax_id": 559292, "disease": "", "pathway": " (sce:YCR008W); (R-SCE-176187); (R-SCE-5693616); (R-SCE-69601)", "pathway_count": 4, "publication_count": 14, "publication_id_list": "10207057;14562106;1574125;1580102;17330950;1767593;19779198;20489023;23749301;24374639;32597660;33481703;33491328;34965436", "class_list": "", "function": "Promotes K(+) uptake, by the potassium transporter TRK1-TRK2, which leads to the subsequent cellular resistance to toxic cations such as Na(+), Li(+) and Ca(2+)., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VR17", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;3.1.3.48;2.7.11.13;3.6.4.-;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0000082 G1/S transition of mitotic cell cycle;GO:0008104 intracellular protein localization;GO:0009249 protein lipoylation;GO:0045807 positive regulation of endocytosis;GO:0030003 intracellular monoatomic cation homeostasis", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P25333-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25336-1", "uniprot_id": "MSH3_YEAST", "mass": 116534.0, "length": 1018, "protein_name": "DNA mismatch repair protein MSH3", "gene_name": "MSH3", "organism": "Yeast", "refseq_name": "mismatch repair protein MSH3", "refseq_ac": "NP_010016", "gene_names_uniprotkb": "MSH3; YCR1152; YCR92C", "gene_names_refseq": "MSH3", "protein_names_uniprotkb": "DNA mismatch repair protein MSH3; MBP; Mismatch-binding protein; MutS protein homolog 3", "protein_names_refseq": "mismatch repair protein MSH3", "tax_id": 559292, "disease": "colorectal carcinoma (Disease Ontology:DOID:0080199); familial adenomatous polyposis 4 (Disease Ontology:DOID:0080412); endometrial cancer (Disease Ontology:DOID:1380); cancer (Disease Ontology:DOID:162); endometrial carcinoma (Disease Ontology:DOID:2871); lung non-small cell carcinoma (Disease Ontology:DOID:3908)", "pathway": " (sce:YCR092C); (R-SCE-5358606)", "pathway_count": 2, "publication_count": 23, "publication_id_list": "10523644;11005803;12748633;14562095;14562106;1574125;16702432;16781730;17157869;17573527;17636021;1803822;18471978;24374639;33491328;8510668;8600025;8805366;8910404;9111357;9256462;9368761;9770499", "class_list": "", "function": "Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. MSH3 provides substrate-binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch binding, forms a ternary complex with either the MutL alpha or MutL beta heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. MutS beta also has a role in regulation of heteroduplex formation during mitotic and meiotic recombination. MutS beta binds to DNA flap structures predicted to form during recombination, and is required for 3' non-homologous tail removal (NHTR). MutS beta-binding alters the DNA conformation of its substrate at the ds/ssDNA junction and may facilitate its recognition and/or cleavage by the downstream nucleotide excision repair (NER) RAD1-RAD10 endonuclease. ATP binding and hydrolysis play a pivotal role in MMR and NHTR., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 8, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VR92", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0003690 double-stranded DNA binding;GO:0000406 double-strand/single-strand DNA junction binding;GO:0032135 DNA insertion or deletion binding;GO:0140664 ATP-dependent DNA damage sensor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0032302 MutSbeta complex", "go_biological_process": "GO:0006312 mitotic recombination;GO:0000710 meiotic mismatch repair;GO:0006310 DNA recombination;GO:0006298 mismatch repair;GO:0043111 replication fork arrest", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P25336-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25340-1", "uniprot_id": "ERG4_YEAST", "mass": 56040.0, "length": 473, "protein_name": "Delta(24(24(1)))-sterol reductase ERG4", "gene_name": "ERG4", "organism": "Yeast", "refseq_name": "delta(24(24(1)))-sterol reductase", "refseq_ac": "NP_011503", "gene_names_uniprotkb": "ERG4; YGL022", "gene_names_refseq": "ERG4", "protein_names_uniprotkb": "Delta(24(24(1)))-sterol reductase ERG4; 1.3.1.71; C-24(28) sterol reductase ERG4; Ergosterol biosynthetic protein 4; Sterol Delta(24(28))-reductase ERG4", "protein_names_refseq": "delta(24(24(1)))-sterol reductase", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL012W)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10722850;12882006;14562106;16847258;17322287;1882553;1882555;24374639;32679672;33491328;37604855;8125337;9169869", "class_list": "", "function": "C-24(28) sterol reductase; part of the third module of ergosterol biosynthesis pathway that includes the late steps of the pathway (PubMed:10722850, PubMed:12882006, PubMed:8125337). ERG4 Catalyzes the last step of ergosterol biosynthesis by converting ergosta-5,7,22,24(28)-tetraen-3beta-ol into ergosterol (PubMed:10722850, PubMed:12882006). The third module or late pathway involves the ergosterol synthesis itself through consecutive reactions that mainly occur in the endoplasmic reticulum (ER) membrane. Firstly, the squalene synthase ERG9 catalyzes the condensation of 2 farnesyl pyrophosphate moieties to form squalene, which is the precursor of all steroids. Squalene synthase is crucial for balancing the incorporation of farnesyl diphosphate (FPP) into sterol and nonsterol isoprene synthesis. Secondly, the squalene epoxidase ERG1 catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, which is considered to be a rate-limiting enzyme in steroid biosynthesis. Then, the lanosterol synthase ERG7 catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol core. In the next steps, lanosterol is transformed to zymosterol through a complex process involving various demethylation, reduction and desaturation reactions. The lanosterol 14-alpha-demethylase ERG11 (also known as CYP51) catalyzes C14-demethylation of lanosterol to produce 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol, which is critical for ergosterol biosynthesis. The C-14 reductase ERG24 reduces the C14=C15 double bond of 4,4-dimethyl-cholesta-8,14,24-trienol to produce 4,4-dimethyl-cholesta-8,24-dienol. 4,4-dimethyl-cholesta-8,24-dienol is substrate of the C-4 demethylation complex ERG25-ERG26-ERG27 in which ERG25 catalyzes the three-step monooxygenation required for the demethylation of 4,4-dimethyl and 4alpha-methylsterols, ERG26 catalyzes the oxidative decarboxylation that results in a reduction of the 3-beta-hydroxy group at the C-3 carbon to an oxo group, and ERG27 is responsible for the reduction of the keto group on the C-3. ERG28 has a role as a scaffold to help anchor ERG25, ERG26 and ERG27 to the endoplasmic reticulum and ERG29 regulates the activity of the iron-containing C4-methylsterol oxidase ERG25. Then, the sterol 24-C-methyltransferase ERG6 catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. The C-8 sterol isomerase ERG2 catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols and thus converts fecosterol to episterol. The sterol-C5-desaturase ERG3 then catalyzes the introduction of a C-5 double bond in the B ring to produce 5-dehydroepisterol. The C-22 sterol desaturase ERG5 further converts 5-dehydroepisterol into ergosta-5,7,22,24(28)-tetraen-3beta-ol by forming the C-22(23) double bond in the sterol side chain. Finally, ergosta-5,7,22,24(28)-tetraen-3beta-ol is substrate of the C-24(28) sterol reductase ERG4 to produce ergosterol (PubMed:32679672)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VUC5;E9P929", "ec_number_list": "1.3.1.71", "go_molecular_function": "GO:0000246 Delta24(24-1) sterol reductase activity;GO:0050614 Delta24-sterol reductase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006696 ergosterol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P25340-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25341-1", "uniprot_id": "KIN82_YEAST", "mass": 81462.0, "length": 720, "protein_name": "Serine/threonine-protein kinase KIN82", "gene_name": "KIN82", "organism": "Yeast", "refseq_name": "putative serine/threonine protein kinase KIN82", "refseq_ac": "NP_010015", "gene_names_uniprotkb": "KIN82; FPK2; YCR1153; YCR91W", "gene_names_refseq": "FPK2; KIN82", "protein_names_uniprotkb": "Serine/threonine-protein kinase KIN82; 2.7.11.1; Flippase kinase 2", "protein_names_refseq": "putative serine/threonine protein kinase KIN82", "tax_id": 559292, "disease": "", "pathway": " (sce:YCR091W)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "1574125;1580103;17330950;17563356;18199685;18407956;19779198;19966303;20489023;21177495;23749301;24374639;30516470;32597660;33060204;33481703;33491328", "class_list": "", "function": "Flippase activator that phosphorylates DFN1 and DFN2 and which is involved in the generation of phospholipid asymmetry in membranes by the inward translocation of phospholipids., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 20, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VR91", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0045332 phospholipid translocation;GO:0000749 response to pheromone triggering conjugation with cellular fusion", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P25341-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25342-1", "uniprot_id": "CDC10_YEAST", "mass": 37025.0, "length": 322, "protein_name": "Cell division control protein 10", "gene_name": "CDC10", "organism": "Yeast", "refseq_name": "septin CDC10", "refseq_ac": "NP_009928", "gene_names_uniprotkb": "CDC10; YCR022; YCR2C", "gene_names_refseq": "CDC10", "protein_names_uniprotkb": "Cell division control protein 10", "protein_names_refseq": "septin CDC10", "tax_id": 559292, "disease": "spermatogenic failure 10 (Disease Ontology:DOID:0070178); brachial plexus neuritis (Disease Ontology:DOID:3689); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (sce:YCR002C)", "pathway_count": 1, "publication_count": 28, "publication_id_list": "12058072;12665577;14562095;14562106;14993234;15282341;1574125;17287358;17330950;17563356;18407956;1872033;18791237;19684113;19779198;20489023;20702584;21126336;21177495;22814378;23749301;24374639;30516470;32597660;33481703;33491328;8791410;9813094", "class_list": "", "function": "Septins are GTPases involved in cytokinesis that assemble early in the cell cycle as a patch at the incipient bud site and form a ring approximate 15 minutes before bud emergence, which transforms into an hour-glass shaped collar of cortical filaments that spans both sides of the mother-bud neck. This collar persists until just before cytokinesis, when it splits into two rings that occupy opposite sides of the neck. The septins at the bud neck serve as a structural scaffold that recruits different components involved in diverse processes at specific stages during the cell cycle. Many proteins bind asymmetrically to the septin collar. The septin assembly is regulated by protein kinases GIN4 and/or CLA4. May act by recruiting MYO1 and HOF1, a protein involved in septation, to the site of cleavage. Septins are also involved in cell morphogenesis, bud site selection, chitin deposition, cell cycle regulation, cell compartmentalization and spore wall formation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VR12", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0010314 phosphatidylinositol-5-phosphate binding;GO:0003924 GTPase activity;GO:0005200 structural constituent of cytoskeleton;GO:0005525 GTP binding", "go_cellular_component": "GO:0005940 septin ring;GO:0015630 microtubule cytoskeleton;GO:0005876 spindle microtubule;GO:0072687 meiotic spindle;GO:0031105 septin complex", "go_biological_process": "GO:0000920 septum digestion after cytokinesis;GO:0010458 exit from mitosis;GO:0000281 mitotic cytokinesis;GO:0008104 intracellular protein localization;GO:0000921 septin ring assembly", "synthesized_glycan_count": 0, "hit_score": 2.9, "record_id": "P25342-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25343-1", "uniprot_id": "RV161_YEAST", "mass": 30250.0, "length": 265, "protein_name": "Reduced viability upon starvation protein 161", "gene_name": "RVS161", "organism": "Yeast", "refseq_name": "amphiphysin-like protein RVS161", "refseq_ac": "NP_009935", "gene_names_uniprotkb": "RVS161; END6; SPE161; YCR9C", "gene_names_refseq": "END6; FUS7; RVS161; SPE161", "protein_names_uniprotkb": "Reduced viability upon starvation protein 161", "protein_names_refseq": "amphiphysin-like protein RVS161", "tax_id": 559292, "disease": "centronuclear myopathy 2 (Disease Ontology:DOID:0111220)", "pathway": " (sce:YCR009C)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "14562106;15665377;1574125;1626432;17287358;1776363;19795423;19823750;2183524;23749301;24374639;32597660;33481703;33491328", "class_list": "", "function": "Component of a cytoskeletal structure that is required for the formation of endocytic vesicles at the plasma membrane level., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VR18", "ec_number_list": "", "go_molecular_function": "GO:0008092 cytoskeletal protein binding", "go_cellular_component": "GO:0005829 cytosol;GO:0015629 actin cytoskeleton;GO:0045121 membrane raft;GO:0030479 actin cortical patch;GO:0005937 mating projection", "go_biological_process": "GO:0006897 endocytosis;GO:0006970 response to osmotic stress;GO:0007015 actin filament organization;GO:0030100 regulation of endocytosis;GO:0042594 response to starvation", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P25343-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25344-1", "uniprot_id": "STE50_YEAST", "mass": 38971.0, "length": 346, "protein_name": "Protein kinase regulator STE50", "gene_name": "STE50", "organism": "Yeast", "refseq_name": "Ste50p", "refseq_ac": "NP_009898", "gene_names_uniprotkb": "STE50; YCL32W", "gene_names_refseq": "STE50", "protein_names_uniprotkb": "Protein kinase regulator STE50", "protein_names_refseq": "Ste50p", "tax_id": 559292, "disease": "", "pathway": " (sce:YCL032W)", "pathway_count": 1, "publication_count": 25, "publication_id_list": "14555477;14562106;14573615;1494345;1574125;16337230;17330950;17563356;18407956;18854322;1897318;19779198;19795423;19823750;20702584;20932477;21177495;23749301;24374639;28270554;31208443;32597660;33229814;33481703;33491328", "class_list": "", "function": "Involved in growth arrest during conjugation. May interact with the G protein alpha subunit., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 9, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 9, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 9, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "D6VQY3;Q3S1N2", "ec_number_list": "", "go_molecular_function": "GO:0032093 SAM domain binding;GO:0019887 protein kinase regulator activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0030010 establishment of cell polarity;GO:0051726 regulation of cell cycle;GO:0038066 p38MAPK cascade;GO:0000750 pheromone-dependent signal transduction involved in conjugation with cellular fusion;GO:0001402 signal transduction involved in filamentous growth", "synthesized_glycan_count": 0, "hit_score": 3.6, "record_id": "P25344-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25346-1", "uniprot_id": "GIT1_YEAST", "mass": 57322.0, "length": 518, "protein_name": "Glycerophosphoinositol transporter 1", "gene_name": "GIT1", "organism": "Yeast", "refseq_name": "Git1p", "refseq_ac": "NP_010022", "gene_names_uniprotkb": "GIT1; YCR137; YCR98C", "gene_names_refseq": "GIT1", "protein_names_uniprotkb": "Glycerophosphoinositol transporter 1", "protein_names_refseq": "Git1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YCR098C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "12912892;1574125;1574927;16141200;16847258;16924500;19779198;20133652;24374639;26928762;33481703;33491328;9691030", "class_list": "", "function": "Glycerophosphodiester transporter that mediates uptake of both glycerophosphoinositol (GroPIns) and glycerophosphocholine (GroPCho) as sources of the nutrients inositol and phosphate (PubMed:12912892, PubMed:16141200, PubMed:9691030). Also transports glycerol-3-phosphate (Gly3P) into the cell (PubMed:20133652)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VR99", "ec_number_list": "", "go_molecular_function": "GO:0015169 glycerol-3-phosphate transmembrane transporter activity;GO:0001406 glycerophosphodiester transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0015794 glycerol-3-phosphate transmembrane transport;GO:0055085 transmembrane transport;GO:0001407 glycerophosphodiester transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P25346-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25353-1", "uniprot_id": "NPP1_YEAST", "mass": 84734.0, "length": 742, "protein_name": "Ectonucleotide pyrophosphatase/phosphodiesterase 1", "gene_name": "NPP1", "organism": "Yeast", "refseq_name": "nucleotide diphosphatase/phosphodiesterase NPP1", "refseq_ac": "NP_009955", "gene_names_uniprotkb": "NPP1; YCR246; YCR26C", "gene_names_refseq": "NPP1", "protein_names_uniprotkb": "Ectonucleotide pyrophosphatase/phosphodiesterase 1; E-NPP 1; Nucleotide diphosphatase", "protein_names_refseq": "nucleotide diphosphatase/phosphodiesterase NPP1", "tax_id": 559292, "disease": "arterial calcification of infancy (Disease Ontology:DOID:0050644); stroke (Disease Ontology:DOID:0051061); ossification of the posterior longitudinal ligament of spine (Disease Ontology:DOID:0060887); aortic valve disease 1 (Disease Ontology:DOID:0080333); otitis media (Disease Ontology:DOID:10754); spondyloarthropathy (Disease Ontology:DOID:1123); tympanosclerosis (Disease Ontology:DOID:1214); cardiovascular system disease (Disease Ontology:DOID:1287); proliferative diabetic retinopathy (Disease Ontology:DOID:13207); pseudoxanthoma elasticum (Disease Ontology:DOID:2738); glioblastoma (Disease Ontology:DOID:3068); end stage renal disease (Disease Ontology:DOID:783); osteoarthritis (Disease Ontology:DOID:8398); type 2 diabetes mellitus (Disease Ontology:DOID:9352); obesity (Disease Ontology:DOID:9970)", "pathway": " (sce:YCR026C); (R-SCE-196843); (R-SCE-6798695); (R-SCE-6814848); (R-SCE-9840310)", "pathway_count": 5, "publication_count": 9, "publication_id_list": "14562106;1574125;1574926;16278456;18407956;19756047;23749301;24374639;33481703", "class_list": "", "function": "Mediates extracellular nucleotide derived phosphate hydrolysis along with NPP2 and PHO5., [UniProtKB, PubMed]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 15, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6VR36;Q8NIL9", "ec_number_list": "3.1.4.1;3.6.1.9", "go_molecular_function": "GO:0004528 phosphodiesterase I activity;GO:0047429 nucleoside triphosphate diphosphatase activity;GO:0017111 ribonucleoside triphosphate phosphatase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0016036 cellular response to phosphate starvation;GO:0009141 nucleoside triphosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P25353-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25357-1", "uniprot_id": "SNT1_YEAST", "mass": 138397.0, "length": 1226, "protein_name": "Probable DNA-binding protein SNT1", "gene_name": "SNT1", "organism": "Yeast", "refseq_name": "Snt1p", "refseq_ac": "NP_009962", "gene_names_uniprotkb": "SNT1; YCR33W; YCR592", "gene_names_refseq": "SNT1", "protein_names_uniprotkb": "Probable DNA-binding protein SNT1; SANT domain-containing protein 1", "protein_names_refseq": "Snt1p", "tax_id": 559292, "disease": "developmental disorder of mental health (Disease Ontology:DOID:0060037); Huntington's disease (Disease Ontology:DOID:12858); breast cancer (Disease Ontology:DOID:1612); endometrial carcinoma (Disease Ontology:DOID:2871); myelofibrosis (Disease Ontology:DOID:4971); osteoarthritis (Disease Ontology:DOID:8398)", "pathway": " (sce:YCR033W)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "11711434;14562106;1574125;17563356;1776366;18407956;1872032;19779198;20702584;21126336;23749301;24374639;30516470;32109413;32597660;33229814;33481703;33491328", "class_list": "", "function": "Part of the Set3C complex, which is required to repress early/middle sporulation genes during meiosis., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 5, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 5, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 5, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 25, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 6, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6VR43;Q02397;Q8NIL8", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0000785 chromatin;GO:0000118 histone deacetylase complex;GO:0034967 Set3 complex", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0006974 DNA damage response;GO:0009267 cellular response to starvation;GO:0045835 negative regulation of meiotic nuclear division", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "P25357-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25358-1", "uniprot_id": "ELO2_YEAST", "mass": 40002.0, "length": 347, "protein_name": "Fatty acid elongase 2", "gene_name": "ELO2", "organism": "Yeast", "refseq_name": "fatty acid elongase ELO2", "refseq_ac": "NP_009963", "gene_names_uniprotkb": "ELO2; FEN1; GNS1; VBM2; YCR34W; YCR521", "gene_names_refseq": "ELO2; FEN1; GNS1; VBM2", "protein_names_uniprotkb": "Fatty acid elongase 2; 2.3.1.199; 3-keto acyl-CoA synthase ELO2; Elongation of fatty acids protein 2; Fenpropimorph resistance protein 1; Glucan synthesis protein 1; Very-long-chain 3-oxoacyl-CoA synthase 2; v-SNARE bypass mutant gene 2 protein", "protein_names_refseq": "fatty acid elongase ELO2", "tax_id": 559292, "disease": "spinocerebellar ataxia 38 (Disease Ontology:DOID:0050985); adrenoleukodystrophy (Disease Ontology:DOID:10588); diabetic retinopathy (Disease Ontology:DOID:8947)", "pathway": " (sce:YCR034W)", "pathway_count": 1, "publication_count": 31, "publication_id_list": "11875433;12087109;12684876;14562095;14562106;1574125;16847258;17287358;17330950;17563356;17719544;1776366;18407956;1964349;19684113;19779198;20702584;21126336;21177495;22218487;22814378;23749301;24374639;29458843;32597660;33481703;33491328;7768822;8246690;9211877;9832547", "class_list": "", "function": "Component of a microsomal membrane-bound long-chain fatty acid elongation system, which produces the 20-26-carbon very long-chain fatty acids (VLCFA) from long-chain fatty acid precursors and is involved ceramide and inositol sphingolipid biosynthesis. Component of elongase II, which elongates 16-18 carbon fatty acyl-CoAs such as palmitoyl-CoA and stearoyl-CoA to 20-22-carbon fatty acids by incorporation of malonyl-CoA (PubMed:12684876, PubMed:9211877). Involved in the synthesis of 1,3-beta-glucan (PubMed:7768822). The enzymes active site faces the cytosol, whereas VLCFA length is determined by a lysine near the luminal end of transmembrane helix 6 (PubMed:17719544). Plays an important role in lipotoxic cell death induced by oleic acid through maintaining a balanced fatty acid composition in thr plasma membrane (PubMed:29458843)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 1, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VR44", "ec_number_list": "2.3.1.199", "go_molecular_function": "GO:0009922 fatty acid elongase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0030148 sphingolipid biosynthetic process;GO:0016192 vesicle-mediated transport;GO:0030497 fatty acid elongation;GO:0034625 fatty acid elongation, monounsaturated fatty acid;GO:0034626 fatty acid elongation, polyunsaturated fatty acid", "synthesized_glycan_count": 0, "hit_score": 3.2, "record_id": "P25358-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25359-1", "uniprot_id": "RRP43_YEAST", "mass": 44011.0, "length": 394, "protein_name": "Exosome complex component RRP43", "gene_name": "RRP43", "organism": "Yeast", "refseq_name": "exosome non-catalytic core subunit RRP43", "refseq_ac": "NP_009964", "gene_names_uniprotkb": "RRP43; YCR35C; YCR522", "gene_names_refseq": "RRP43", "protein_names_uniprotkb": "Exosome complex component RRP43; Ribosomal RNA-processing protein 43", "protein_names_refseq": "exosome non-catalytic core subunit RRP43", "tax_id": 559292, "disease": "pontocerebellar hypoplasia type 1C (Disease Ontology:DOID:0112334)", "pathway": " (sce:YCR035C); (R-SCE-429958); (R-SCE-450385); (R-SCE-450513); (R-SCE-6791226)", "pathway_count": 5, "publication_count": 19, "publication_id_list": "10465791;12364597;14562095;14562106;1574125;16829593;17173052;17174896;1776366;18407956;1964349;22814378;24374639;30181345;32597660;33481703;33491328;9390555;9973615", "class_list": "", "function": "Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and in RNA surveillance pathways, preventing translation of aberrant mRNAs. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. RRP43 is part of the hexameric ring of RNase PH domain-containing subunits proposed to form a central channel which threads RNA substrates for degradation., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VR45;Q8NKJ5", "ec_number_list": "", "go_molecular_function": "GO:0035925 mRNA 3'-UTR AU-rich region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0000176 nuclear exosome (RNase complex)", "go_biological_process": "GO:0071028 nuclear mRNA surveillance;GO:0034473 U1 snRNA 3'-end processing;GO:0034476 U5 snRNA 3'-end processing;GO:0071042 nuclear polyadenylation-dependent mRNA catabolic process;GO:0006396 RNA processing", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P25359-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25364-1", "uniprot_id": "HCM1_YEAST", "mass": 63647.0, "length": 564, "protein_name": "Forkhead transcription factor HCM1", "gene_name": "HCM1", "organism": "Yeast", "refseq_name": "Hcm1p", "refseq_ac": "NP_009991", "gene_names_uniprotkb": "HCM1; YCR65W; YCR902", "gene_names_refseq": "HCM1", "protein_names_uniprotkb": "Forkhead transcription factor HCM1; High-copy suppressor of calmodulin protein 1", "protein_names_refseq": "Hcm1p", "tax_id": 559292, "disease": "Kartagener syndrome (Disease Ontology:DOID:0050144); primary ovarian insufficiency 3 (Disease Ontology:DOID:0080860); primary ciliary dyskinesia 43 (Disease Ontology:DOID:0111856); blepharophimosis, ptosis, and epicanthus inversus syndrome (Disease Ontology:DOID:14778); congenital heart disease (Disease Ontology:DOID:1682); laryngeal squamous cell carcinoma (Disease Ontology:DOID:2876); granulosa cell tumor (Disease Ontology:DOID:2999); lung non-small cell carcinoma (Disease Ontology:DOID:3908); type 2 diabetes mellitus (Disease Ontology:DOID:9352); primary ciliary dyskinesia (Disease Ontology:DOID:9562)", "pathway": " (sce:YCR065W); (R-SCE-3232118); (R-SCE-9018519)", "pathway_count": 3, "publication_count": 18, "publication_id_list": "14562095;14562106;14574415;1561837;1574125;18407956;21126336;21177495;22218487;23749301;24374639;26729465;32597660;33481703;33491328;33502312;8441413;9920414", "class_list": "", "function": "Transcription factor regulating the cell cycle specific transcription of a spindle pole body (SPB) calmodulin binding protein SPC110. Required for full induction of SPC110 transcription in late G1. Binds to DNA consensus sequence 5'-[AT]AA[TC]AAACAA[AT]-3'. Dosage dependent suppressor of calmodulin mutants which have specific defects in SPB assembly., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 49, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VR68", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding;GO:0034246 mitochondrial transcription factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0000785 chromatin", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0034599 cellular response to oxidative stress;GO:0007005 mitochondrion organization;GO:1903108 regulation of mitochondrial transcription", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P25364-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25367-1", "uniprot_id": "RNQ1_YEAST", "mass": 42580.0, "length": 405, "protein_name": "[PIN+] prion protein RNQ1", "gene_name": "RNQ1", "organism": "Yeast", "refseq_name": "prion domain-containing protein RNQ1", "refseq_ac": "NP_009902", "gene_names_uniprotkb": "RNQ1; YCL181; YCL28W", "gene_names_refseq": "RNQ1", "protein_names_uniprotkb": "[PIN+] prion protein RNQ1; Rich in asparagine and glutamine protein 1", "protein_names_refseq": "prion domain-containing protein RNQ1", "tax_id": 559292, "disease": "", "pathway": " (sce:YCL028W)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "10678178;11511345;12890024;14562095;14562106;1574125;17097676;18268327;18407956;1897318;22106047;23749301;24374639;3302672;33491328;9335589", "class_list": "", "function": "Transferable epigenetic modifier which forms a prion responsible for the non-Mendelian trait [PIN+]. The native function of the soluble protein is unknown., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQY7;Q8NKJ9;Q8TF94;Q8TFA2;Q8TFC8;Q8TFP4;Q8TFP5;Q8TFP6;Q8TFP7;Q8TFP8", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P25367-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25368-1", "uniprot_id": "RRP7_YEAST", "mass": 34470.0, "length": 297, "protein_name": "Ribosomal RNA-processing protein 7", "gene_name": "RRP7", "organism": "Yeast", "refseq_name": "Rrp7p", "refseq_ac": "NP_009899", "gene_names_uniprotkb": "RRP7; YCL184; YCL31C", "gene_names_refseq": "RRP7", "protein_names_uniprotkb": "Ribosomal RNA-processing protein 7", "protein_names_refseq": "Rrp7p", "tax_id": 559292, "disease": "primary autosomal recessive microcephaly 28 (Disease Ontology:DOID:0051039); primary microcephaly (Disease Ontology:DOID:0070297)", "pathway": " (sce:YCL031C); (R-SCE-6791226)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "14562095;14562106;1574125;17515605;1897318;24374639;33491328;7049842;9271380", "class_list": "", "function": "Plays an important role in the synthesis of 18S rRNA but is not required for the 5.8S and 25S pathway. Is necessary for the cleavage at site A2. Is required for efficient association of RPS27 with the pre-ribosomal particle., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQY4", "ec_number_list": "", "go_molecular_function": "GO:0019843 rRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0032545 CURI complex;GO:0034456 UTP-C complex", "go_biological_process": "GO:0006364 rRNA processing;GO:0030490 maturation of SSU-rRNA;GO:0000028 ribosomal small subunit assembly;GO:0042790 nucleolar large rRNA transcription by RNA polymerase I;GO:0060962 regulation of ribosomal protein gene transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P25368-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25369-1", "uniprot_id": "LSB5_YEAST", "mass": 39872.0, "length": 354, "protein_name": "LAS seventeen-binding protein 5", "gene_name": "LSB5", "organism": "Yeast", "refseq_name": "Lsb5p", "refseq_ac": "NP_009896", "gene_names_uniprotkb": "LSB5; YCL186; YCL34W", "gene_names_refseq": "LSB5", "protein_names_uniprotkb": "LAS seventeen-binding protein 5; LAS17-binding protein 5", "protein_names_refseq": "Lsb5p", "tax_id": 559292, "disease": "", "pathway": " (sce:YCL034W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10512884;12388763;1574125;18407956;1897318;19779198;23749301;24374639;30516470;33481703;33491328", "class_list": "", "function": "Essential for the organization of the actin cytoskeleton, fluid phase endocytosis and vesicle trafficking, together with YSC84., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQY1;P87004;Q8NIM9", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005938 cell cortex;GO:0030479 actin cortical patch", "go_biological_process": "GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0030036 actin cytoskeleton organization;GO:0051666 actin cortical patch localization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P25369-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25373-1", "uniprot_id": "GLRX1_YEAST", "mass": 12380.0, "length": 110, "protein_name": "Glutaredoxin-1", "gene_name": "GRX1", "organism": "Yeast", "refseq_name": "dithiol glutaredoxin GRX1", "refseq_ac": "NP_009895", "gene_names_uniprotkb": "GRX1; YCL35C", "gene_names_refseq": "GRX1", "protein_names_uniprotkb": "Glutaredoxin-1; 1.11.1.9; 2.5.1.18; Glutathione-dependent oxidoreductase 1", "protein_names_refseq": "dithiol glutaredoxin GRX1", "tax_id": 559292, "disease": "Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (sce:YCL035C)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10786615;11875065;12684511;14562095;14562106;1574125;17327665;18473363;18992757;20417731;22106047;24374639;33491328;9571241", "class_list": "", "function": "Component of the glutathione system which performs several activities such as glutathione-dependent oxidoreductase, glutathione peroxidase and glutathione S-transferase (GST) activity (PubMed:11875065, PubMed:12684511). The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing cytosolic protein- and non-protein-disulfides in a coupled system with glutathione reductase. Required for resistance to reactive oxygen species (ROS) by directly reducing hydroperoxides and for the detoxification of ROS-mediated damage. GRX1 is less active as an oxidoreductase than GRX2 (PubMed:18992757, PubMed:20417731, PubMed:9571241)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQY0", "ec_number_list": "1.11.1.9;2.5.1.18;1.8.4.-;1.11.1.24;1.8.5.1", "go_molecular_function": "GO:0004364 glutathione transferase activity;GO:0015038 glutathione disulfide oxidoreductase activity;GO:0004602 glutathione peroxidase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0034599 cellular response to oxidative stress;GO:0010731 protein glutathionylation", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P25373-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25374-1", "uniprot_id": "NFS1_YEAST", "mass": 54467.0, "length": 497, "protein_name": "Cysteine desulfurase", "gene_name": "NFS1", "organism": "Yeast", "refseq_name": "cysteine desulfurase", "refseq_ac": "NP_009912", "gene_names_uniprotkb": "NFS1; SPL1", "gene_names_refseq": "NFS1; SPL1", "protein_names_uniprotkb": "Cysteine desulfurase; 2.8.1.7; tRNA-splicing protein SPL1", "protein_names_refseq": "cysteine desulfurase", "tax_id": 559292, "disease": "combined oxidative phosphorylation deficiency 52 (Disease Ontology:DOID:0070425)", "pathway": " (sce:YCL017C); (R-SCE-1362409); (R-SCE-947581); (R-SCE-9865881)", "pathway_count": 4, "publication_count": 15, "publication_id_list": "10406803;10551871;14562106;14722066;15220327;1574125;19720832;23615440;24374639;28941588;31040179;32597660;33491328;6396161;8444805", "class_list": "", "function": "Catalyzes the removal of elemental sulfur from cysteine to produce alanine (PubMed:15220327). It supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters (PubMed:10406803, PubMed:10551871, PubMed:15220327, PubMed:31040179). Plays a role in both tRNA-processing and mitochondrial metabolism (PubMed:15220327). Involved in the 2-thio-modification of both 5-carboxymethylaminomethyl-2-thiouridine in mitochondrial tRNAs and 5-methoxycarbonylmethyl-2-thiouridine (mcm5s2U) in cytoplasmic tRNAs (PubMed:14722066, PubMed:15220327, PubMed:8444805)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQZ7", "ec_number_list": "7.1.1.8;3.6.4.10;2.8.1.7;1.16.3.1", "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0046872 metal ion binding;GO:0051536 iron-sulfur cluster binding;GO:0031071 cysteine desulfurase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:1990221 L-cysteine desulfurase complex", "go_biological_process": "GO:0016226 iron-sulfur cluster assembly;GO:0034227 tRNA thio-modification;GO:0006879 intracellular iron ion homeostasis;GO:0002098 tRNA wobble uridine modification;GO:0044571 [2Fe-2S] cluster assembly", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P25374-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25375-1", "uniprot_id": "PRTD_YEAST", "mass": 81934.0, "length": 712, "protein_name": "Saccharolysin", "gene_name": "PRD1", "organism": "Yeast", "refseq_name": "metalloendopeptidase", "refseq_ac": "NP_009874", "gene_names_uniprotkb": "PRD1; YCL57W", "gene_names_refseq": "PRD1", "protein_names_uniprotkb": "Saccharolysin; 3.4.24.37; Oligopeptidase YSCD; Protease D; Proteinase yscD", "protein_names_refseq": "metalloendopeptidase", "tax_id": 559292, "disease": "", "pathway": " (sce:YCL057W); (R-SCE-983168)", "pathway_count": 2, "publication_count": 13, "publication_id_list": "14562106;1574125;17322287;17330950;18407956;19779198;19795423;19823750;21126336;24374639;33481703;33491328;8307027", "class_list": "", "function": "Could be involved in late stage of protein degradation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQW0;E9P942", "ec_number_list": "3.4.24.37", "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005758 mitochondrial intermembrane space;GO:0005794 Golgi apparatus;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P25375-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25376-1", "uniprot_id": "AGP1_YEAST", "mass": 69671.0, "length": 633, "protein_name": "General amino acid permease AGP1", "gene_name": "AGP1", "organism": "Yeast", "refseq_name": "amino acid transporter AGP1", "refseq_ac": "NP_009905", "gene_names_uniprotkb": "AGP1; YCL25C", "gene_names_refseq": "AGP1; WAP1; YCC5", "protein_names_uniprotkb": "General amino acid permease AGP1; Asparagine/glutamine permease", "protein_names_refseq": "amino acid transporter AGP1", "tax_id": 559292, "disease": "retinitis pigmentosa 68 (Disease Ontology:DOID:0110374); sensorineural hearing loss (Disease Ontology:DOID:10003); blindness (Disease Ontology:DOID:1432)", "pathway": " (sce:YCL025C)", "pathway_count": 1, "publication_count": 26, "publication_id_list": "10467005;10654085;11154269;12844361;14562106;14697254;15126393;1574125;16751107;16847258;18407956;19779198;19795423;19823750;21177495;22118465;22218487;23749301;24374639;24909858;32597660;33481703;33491328;34965436;9573211;9891035", "class_list": "", "function": "Broad substrate range permease which transports asparagine and glutamine with intermediate specificity. Also transports Ala, Cys, Gly, Ile, Leu, Met, Phe, Ser, Thr, Tyr and Val. Important for the utilization of amino acids as a nitrogen source., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQZ1", "ec_number_list": "", "go_molecular_function": "GO:0015193 L-proline transmembrane transporter activity;GO:0015171 amino acid transmembrane transporter activity;GO:0015192 L-phenylalanine transmembrane transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0055085 transmembrane transport;GO:0006865 amino acid transport;GO:0003333 amino acid transmembrane transport;GO:0098718 serine import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 2.7, "record_id": "P25376-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25377-1", "uniprot_id": "ADH7_YEAST", "mass": 39348.0, "length": 361, "protein_name": "NADP-dependent alcohol dehydrogenase 7", "gene_name": "ADH7", "organism": "Yeast", "refseq_name": "NADP-dependent alcohol dehydrogenase", "refseq_ac": "NP_010030", "gene_names_uniprotkb": "ADH7", "gene_names_refseq": "ADH7; ADHVII", "protein_names_uniprotkb": "NADP-dependent alcohol dehydrogenase 7; 1.1.1.2; ADHVII; NADP-dependent alcohol dehydrogenase VII", "protein_names_refseq": "NADP-dependent alcohol dehydrogenase", "tax_id": 559292, "disease": "", "pathway": " (sce:YCR105W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "12423374;14562106;1574125;17287358;24374639", "class_list": "", "function": "NADP-dependent alcohol dehydrogenase with a broad substrate specificity. The oxidative reactions are more than 100 times less efficient than the corresponding reductions, suggesting that the enzyme acts as an aldehyde reductase, rather than as an alcohol dehydrogenase., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRA5", "ec_number_list": "1.1.1.2;1.6.-.-;1.1.1.265;1.1.1.283", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0008106 alcohol dehydrogenase (NADP+) activity;GO:0052675 3-methylbutanal reductase (NADPH) activity;GO:0045551 cinnamyl-alcohol dehydrogenase activity", "go_cellular_component": "", "go_biological_process": "GO:0006066 alcohol metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P25377-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25378-1", "uniprot_id": "RHEB_YEAST", "mass": 23338.0, "length": 209, "protein_name": "GTP-binding protein RHB1", "gene_name": "RHB1", "organism": "Yeast", "refseq_name": "putative GTPase RHB1", "refseq_ac": "NP_009956", "gene_names_uniprotkb": "RHB1; RSG1; YCR27C", "gene_names_refseq": "RHB1; RSG1", "protein_names_uniprotkb": "GTP-binding protein RHB1; 3.6.5.-; GTP-binding protein RSG1", "protein_names_refseq": "putative GTPase RHB1", "tax_id": 559292, "disease": "disease of metabolism (Disease Ontology:DOID:0014667); tuberous sclerosis (Disease Ontology:DOID:13515); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (sce:YCR027C); (R-SCE-165159); (R-SCE-9639288)", "pathway_count": 3, "publication_count": 8, "publication_id_list": "10753927;12456008;14562106;1574125;17322287;22814378;24374639;2989539", "class_list": "", "function": "Binds GTP and exhibits intrinsic GTPase activity (By similarity). Involved in the regulation of arginine and lysine uptake (PubMed:12456008). Acts through the CAN1 permease (PubMed:12456008)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VR37;Q8NKJ6", "ec_number_list": "3.6.5.2;3.6.5.3;3.6.5.-;3.1.-.-;7.1.2.2;3.6.5.4;3.6.5.5;2.7.1.67;2.7.11.1", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0043539 protein serine/threonine kinase activator activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0007264 small GTPase-mediated signal transduction;GO:0042147 retrograde transport, endosome to Golgi", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P25378-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25384-1", "uniprot_id": "YC21B_YEAST", "mass": 202096.0, "length": 1770, "protein_name": "Transposon Ty2-C Gag-Pol polyprotein", "gene_name": "TY2B-C", "organism": "Yeast", "refseq_name": "gag-pol fusion protein", "refseq_ac": "NP_009909", "gene_names_uniprotkb": "TY2B-C; YCL19W; YCLWTy2-1 POL", "gene_names_refseq": "", "protein_names_uniprotkb": "Transposon Ty2-C Gag-Pol polyprotein; TY2A-TY2B; Transposon Ty2 TYA-TYB polyprotein", "protein_names_refseq": "gag-pol fusion protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YCL019W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "1574125;16093660;17330950;17563356;18407956;19779198;24374639;2997719;3010239;9582191", "class_list": "", "function": "Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA also has nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty2 RNA and initiation of reverse transcription (By similarity)., [UniProtKB]; Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome (By similarity)., [UniProtKB]; Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends (By similarity)., [UniProtKB]; The aspartyl protease (PR) mediates the proteolytic cleavages of the Gag and Gag-Pol polyproteins after assembly of the VLP., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQZ4;P87006", "ec_number_list": "2.7.7.7;3.1.26.4;2.7.7.49;3.4.23.-;3.1.11.-", "go_molecular_function": "GO:0003887 DNA-directed DNA polymerase activity;GO:0003964 RNA-directed DNA polymerase activity;GO:0003677 DNA binding;GO:0003723 RNA binding;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006310 DNA recombination;GO:0006508 proteolysis;GO:0032196 transposition;GO:0015074 DNA integration;GO:0075523 viral translational frameshifting", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P25384-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25385-1", "uniprot_id": "BOS1_YEAST", "mass": 27500.0, "length": 244, "protein_name": "Protein transport protein BOS1", "gene_name": "BOS1", "organism": "Yeast", "refseq_name": "Bos1p", "refseq_ac": "NP_013179", "gene_names_uniprotkb": "BOS1; L9449.9", "gene_names_refseq": "BOS1; SEC32", "protein_names_uniprotkb": "Protein transport protein BOS1; Bet one suppressor 1", "protein_names_refseq": "Bos1p", "tax_id": 559292, "disease": "progressive myoclonus epilepsy 6 (Disease Ontology:DOID:0111449); progressive myoclonus epilepsy (Disease Ontology:DOID:891)", "pathway": " (sce:YLR078C); (R-SCE-204005); (R-SCE-5694530); (R-SCE-6807878)", "pathway_count": 4, "publication_count": 7, "publication_id_list": "11001058;12657649;2007627;22814378;24374639;33491328;9169871", "class_list": "", "function": "SNARE required for targeting and fusion of ER-derived transport vesicles with the Golgi complex., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VY78", "ec_number_list": "", "go_molecular_function": "GO:0000149 SNARE binding;GO:0005484 SNAP receptor activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane;GO:0031902 late endosome membrane", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006906 vesicle fusion;GO:0048280 vesicle fusion with Golgi apparatus", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P25385-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25386-1", "uniprot_id": "USO1_YEAST", "mass": 206452.0, "length": 1790, "protein_name": "Intracellular protein transport protein USO1", "gene_name": "USO1", "organism": "Yeast", "refseq_name": "Uso1p", "refseq_ac": "NP_010225", "gene_names_uniprotkb": "USO1; INT1", "gene_names_refseq": "INT1; USO1", "protein_names_uniprotkb": "Intracellular protein transport protein USO1; Int-1", "protein_names_refseq": "Uso1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL058W); (R-SCE-6807878)", "pathway_count": 2, "publication_count": 21, "publication_id_list": "14562106;17192843;17563356;18407956;19684113;19779198;2010462;23749301;24374639;32597660;33481703;33491328;7582869;7706227;8166741;8603910;8769646;8812994;9169867;9382859;9545229", "class_list": "", "function": "Required for vesicle-mediated protein transport from the ER to the Golgi complex (PubMed:2010462, PubMed:8166741, PubMed:9382859). It is recruited to the ER-derived vesicles and acts as an effector protein on the coated vesicle for the Ypt/Rab GTPase YPT1 on the Golgi membrane, which regulates COP II-coated vesicle trafficking and fusion in a nucleotide (GTP/GDP) bound manner (PubMed:17192843, PubMed:8603910, PubMed:9545229)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRT8;E9PAG8;P89892;Q07380", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005856 cytoskeleton;GO:0005789 endoplasmic reticulum membrane;GO:0012507 ER to Golgi transport vesicle membrane", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0061025 membrane fusion;GO:0035493 SNARE complex assembly;GO:0048211 Golgi vesicle docking", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P25386-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25389-1", "uniprot_id": "KCC4_YEAST", "mass": 116475.0, "length": 1037, "protein_name": "Probable serine/threonine-protein kinase KCC4", "gene_name": "KCC4", "organism": "Yeast", "refseq_name": "serine/threonine protein kinase", "refseq_ac": "NP_009907", "gene_names_uniprotkb": "KCC4; YCL24W", "gene_names_refseq": "KCC4", "protein_names_uniprotkb": "Probable serine/threonine-protein kinase KCC4; 2.7.11.1", "protein_names_refseq": "serine/threonine protein kinase", "tax_id": 559292, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041); depressive disorder (Disease Ontology:DOID:1596)", "pathway": " (sce:YCL024W)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "11165249;12773812;14562106;15665377;1574125;17563356;18086883;18407956;19684113;19779198;19795423;19823750;20489023;20702584;21126336;22218487;23749301;24374639;30516470;32597660;33481703;33491328;9925642", "class_list": "", "function": "Involved in regulation of bud growth during cell cycle and in septin organization. Plays a role in cell wall synthesis., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 63, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VQZ2;P87005;Q8NKJ8", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0001786 phosphatidylserine binding", "go_cellular_component": "GO:0005940 septin ring;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0000131 incipient cellular bud site", "go_biological_process": "GO:0000086 G2/M transition of mitotic cell cycle;GO:0008360 regulation of cell shape;GO:0000921 septin ring assembly;GO:0007117 budding cell bud growth;GO:0044879 mitotic morphogenesis checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P25389-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25441-1", "uniprot_id": "RPC4_YEAST", "mass": 46667.0, "length": 422, "protein_name": "DNA-directed RNA polymerase III subunit RPC4", "gene_name": "RPC53", "organism": "Yeast", "refseq_name": "DNA-directed RNA polymerase III subunit C53", "refseq_ac": "NP_010131", "gene_names_uniprotkb": "RPC53; D1557; RPC4", "gene_names_refseq": "RPC4; RPC53", "protein_names_uniprotkb": "DNA-directed RNA polymerase III subunit RPC4; C53; DNA-directed RNA polymerase III 47 kDa polypeptide; RNA polymerase III subunit C4", "protein_names_refseq": "DNA-directed RNA polymerase III subunit C53", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL150W); (R-SCE-76061); (R-SCE-76066)", "pathway_count": 3, "publication_count": 29, "publication_id_list": "10384303;10393904;1406624;14562095;14562106;15665377;16362040;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22218487;22364741;23749301;24374639;30516470;32597660;33481703;33491328;33502312;8972581;9169867", "class_list": "", "function": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Essential for tRNA synthesis. The RPC53/RPC4-RPC37/RPC5 subcomplex is required for terminator recognition and reinitiation., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 20, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VRJ8;Q12073", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005666 RNA polymerase III complex", "go_biological_process": "GO:0042797 tRNA transcription by RNA polymerase III;GO:0006383 transcription by RNA polymerase III;GO:0006386 termination of RNA polymerase III transcription;GO:0006384 transcription initiation at RNA polymerase III promoter", "synthesized_glycan_count": 0, "hit_score": 3.0, "record_id": "P25441-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25451-1", "uniprot_id": "PSB3_YEAST", "mass": 22605.0, "length": 205, "protein_name": "Proteasome subunit beta type-3", "gene_name": "PUP3", "organism": "Yeast", "refseq_name": "proteasome core particle subunit beta 3", "refseq_ac": "NP_011020", "gene_names_uniprotkb": "PUP3", "gene_names_refseq": "PUP3; SCS32", "protein_names_uniprotkb": "Proteasome subunit beta type-3; Macropain subunit PUP3; Multicatalytic endopeptidase complex subunit PUP3; Proteasome component PUP3", "protein_names_refseq": "proteasome core particle subunit beta 3", "tax_id": 559292, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (sce:YER094C); (R-SCE-1236974); (R-SCE-1236978); (R-SCE-5668541); (R-SCE-5689880); (R-SCE-9907900); (R-SCE-9912633)", "pathway_count": 7, "publication_count": 19, "publication_id_list": "11062564;11081519;1620128;16531229;16608349;16793518;17563356;18407956;20227375;20486117;21126336;22106047;22927375;23749301;24374639;33481703;33491328;9087403;9169868", "class_list": "", "function": "Non-catalytic component of the proteasome which degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity. This subunit may participate in the trypsin-like activity of the enzyme complex., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DM02", "ec_number_list": "", "go_molecular_function": "GO:0061133 endopeptidase activator activity", "go_cellular_component": "GO:0019774 proteasome core complex, beta-subunit complex;GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0010499 proteasomal ubiquitin-independent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P25451-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25453-1", "uniprot_id": "DMC1_YEAST", "mass": 36613.0, "length": 334, "protein_name": "Meiotic recombination protein DMC1", "gene_name": "DMC1", "organism": "Yeast", "refseq_name": "recombinase DMC1", "refseq_ac": "NP_011106", "gene_names_uniprotkb": "DMC1; ISC2", "gene_names_refseq": "DMC1; ISC2", "protein_names_uniprotkb": "Meiotic recombination protein DMC1; 3.6.4.-", "protein_names_refseq": "recombinase DMC1", "tax_id": 559292, "disease": "Sertoli cell-only syndrome (Disease Ontology:DOID:0050457)", "pathway": " (sce:YER179W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "11551925;15620352;1581960;15835894;22955832;23769192;24374639;8455558;9169868;9335591", "class_list": "", "function": "Homologous DNA recombinase that catalyzes strand exchange during meiotic recombination (PubMed:11551925, PubMed:15620352, PubMed:22955832, PubMed:23769192, PubMed:9335591). Specifically required for meiotic recombination, facilitating the search and repair of DNA using the homolog rather than the sister chromatid, and can tolerate mismatches in heteroduplex DNA, unlike the higher-fidelity RAD51 (PubMed:22955832, PubMed:23769192). Recruited to meiosis recombination hotspots by MEI5 and SAE3 (PubMed:15620352)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DM88", "ec_number_list": "3.6.4.13;5.6.2.3;3.6.4.10;3.6.-.-;5.6.2.4;3.6.4.-;5.6.1.4;3.6.4.12;3.6.4.6;5.6.2.5;3.6.1.-;2.3.2.27;3.1.-.-;3.4.24.-;3.6.5.-;2.7.4.3;2.7.11.1;7.2.2.-", "go_molecular_function": "GO:0005524 ATP binding;GO:0003690 double-stranded DNA binding;GO:0003697 single-stranded DNA binding;GO:0042030 ATPase inhibitor activity;GO:0008094 ATP-dependent activity, acting on DNA", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0005634 nucleus", "go_biological_process": "GO:0006312 mitotic recombination;GO:0007130 synaptonemal complex assembly;GO:0007131 reciprocal meiotic recombination;GO:0051321 meiotic cell cycle;GO:0000730 DNA recombinase assembly", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P25453-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25491-1", "uniprot_id": "MAS5_YEAST", "mass": 44671.0, "length": 409, "protein_name": "Mitochondrial protein import protein MAS5", "gene_name": "YDJ1", "organism": "Yeast", "refseq_name": "type I HSP40 co-chaperone YDJ1", "refseq_ac": "NP_014335", "gene_names_uniprotkb": "YDJ1; MAS5; N2418; YNL2418C", "gene_names_refseq": "HSP40; MAB3; MAS5; YDJ1", "protein_names_uniprotkb": "Mitochondrial protein import protein MAS5; Yeast dnaJ protein 1", "protein_names_refseq": "type I HSP40 co-chaperone YDJ1", "tax_id": 559292, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); liver disease (Disease Ontology:DOID:409)", "pathway": " (sce:YNL064C); (R-SCE-3371497); (R-SCE-9841251)", "pathway_count": 3, "publication_count": 17, "publication_id_list": "11689685;14562095;14562106;14656432;1527016;15701512;1729605;18407956;1869583;19779198;22106047;23749301;24374639;33481703;33491328;8533472;9169873", "class_list": "", "function": "Probably involved in mitochondrial protein import. Is also required for efficient translocation of pre-pro-alpha-factor. Involved in heme regulation of HAP1, as a component of the high-molecular-weight (HMC) complex., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1B6", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0051082 unfolded protein binding;GO:0001671 ATPase activator activity;GO:0030544 Hsp70 protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm;GO:0072380 TRC complex", "go_biological_process": "GO:0015031 protein transport;GO:0034605 cellular response to heat;GO:0045892 negative regulation of DNA-templated transcription;GO:0006626 protein targeting to mitochondrion;GO:0009267 cellular response to starvation", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P25491-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25502-1", "uniprot_id": "PUT3_YEAST", "mass": 111414.0, "length": 979, "protein_name": "Proline utilization trans-activator", "gene_name": "PUT3", "organism": "Yeast", "refseq_name": "Put3p", "refseq_ac": "NP_012910", "gene_names_uniprotkb": "PUT3", "gene_names_refseq": "PUT3", "protein_names_uniprotkb": "Proline utilization trans-activator", "protein_names_refseq": "Put3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YKL015W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562106;19574222;2017167;24374639;29242833;33491328;8154185;8196765;9303003;9303004", "class_list": "", "function": "Positive activator of the proline utilization pathway. Binds to the promoters of PUT1 and PUT2 genes. Recognizes and binds to the DNA sequence 5'-CGG-N(10)-CCG-3'., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXS1", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0043565 sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006560 proline metabolic process;GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery;GO:2001158 positive regulation of L-proline catabolic process to L-glutamate", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P25502-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25515-1", "uniprot_id": "VATL1_YEAST", "mass": 16351.0, "length": 160, "protein_name": "V-type proton ATPase subunit c", "gene_name": "VMA3", "organism": "Yeast", "refseq_name": "H(+)-transporting V0 sector ATPase subunit c", "refseq_ac": "NP_010887", "gene_names_uniprotkb": "VMA3; CLS7; CUP5; GEF2", "gene_names_refseq": "CLS7; CUP5; GEF2; VMA3", "protein_names_uniprotkb": "V-type proton ATPase subunit c; Guanine nucleotide exchange factor 2; V-ATPase 16 kDa proteolipid subunit 1; V-ATPase subunit c; Vacuolar proton pump c subunit", "protein_names_refseq": "H(+)-transporting V0 sector ATPase subunit c", "tax_id": 559292, "disease": "early-onset epilepsy 3 (Disease Ontology:DOID:0070472); intellectual disability (Disease Ontology:DOID:1059); epilepsy (Disease Ontology:DOID:1826); thyroid gland carcinoma (Disease Ontology:DOID:3963)", "pathway": " (sce:YEL027W); (R-SCE-1222556); (R-SCE-6798695); (R-SCE-77387); (R-SCE-917977); (R-SCE-9639288)", "pathway_count": 6, "publication_count": 11, "publication_id_list": "14562106;16847258;17322287;1825730;24374639;2540044;25971514;27776355;29526695;9030535;9169868", "class_list": "", "function": "Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:1825730). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (PubMed:1825730)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLM1", "ec_number_list": "", "go_molecular_function": "GO:0015078 proton transmembrane transporter activity;GO:0046961 proton-transporting ATPase activity, rotational mechanism", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0016020 membrane;GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0006878 intracellular copper ion homeostasis;GO:0006897 endocytosis;GO:0006879 intracellular iron ion homeostasis;GO:0048388 endosomal lumen acidification;GO:0007033 vacuole organization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P25515-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25555-1", "uniprot_id": "GBP2_YEAST", "mass": 48729.0, "length": 427, "protein_name": "Serine/arginine (SR)-type shuttling mRNA binding protein GBP2", "gene_name": "GBP2", "organism": "Yeast", "refseq_name": "single-stranded telomeric DNA-binding/mRNA-binding protein", "refseq_ac": "NP_009916", "gene_names_uniprotkb": "GBP2; RLF6; YCL11C", "gene_names_refseq": "GBP2; RLF6", "protein_names_uniprotkb": "Serine/arginine (SR)-type shuttling mRNA binding protein GBP2; G-strand-binding protein 2; Polyadenylate-binding protein GBP2; RAP1 localization factor 6; Single-strand telomeric DNA-binding protein GBP2", "protein_names_refseq": "single-stranded telomeric DNA-binding/mRNA-binding protein", "tax_id": 559292, "disease": "colorectal carcinoma (Disease Ontology:DOID:0080199); leiomyoma (Disease Ontology:DOID:127)", "pathway": " (sce:YCL011C)", "pathway_count": 1, "publication_count": 24, "publication_id_list": "12519786;12634846;14562106;14676199;14769921;1574125;17322287;17563356;18407956;18981231;19684113;21177495;22932476;23749301;24374639;24452287;26602689;32597660;33481703;33491328;33856219;7777547;7800479;9499403", "class_list": "", "function": "Binds to intron-containing transcripts and is involved in quality control for the export of spliced mRNAs from the nucleus (PubMed:14769921, PubMed:24452287). Binds to pre-mRNAs until splicing is completed or until faulty mRNAs are degraded. On correctly spliced mRNAs, GBP2 and HRB1 recruit MEX67 to allow nuclear export. On faulty mRNAs, GBP2 and HRB1 associate with the TRAMP complex that guides those pre-mRNAs to the exosome for degradation (PubMed:24452287). Binds single-stranded telomeric sequences of the type (TG[1-3])n in vitro (PubMed:7800479). Influences the localization of RAP1 in the nuclei (PubMed:7777547). Involved in modulating telomere length (PubMed:12519786)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VR01", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0003729 mRNA binding;GO:0043047 single-stranded telomeric DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0000932 P-body;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0016973 poly(A)+ mRNA export from nucleus;GO:0071028 nuclear mRNA surveillance;GO:0000723 telomere maintenance", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "P25555-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25567-1", "uniprot_id": "SRO9_YEAST", "mass": 48060.0, "length": 434, "protein_name": "RNA-binding protein SRO9", "gene_name": "SRO9", "organism": "Yeast", "refseq_name": "Sro9p", "refseq_ac": "NP_009893", "gene_names_uniprotkb": "SRO9; YCL37C", "gene_names_refseq": "SRO9", "protein_names_uniprotkb": "RNA-binding protein SRO9; Suppressor of RHO3 protein 9", "protein_names_refseq": "Sro9p", "tax_id": 559292, "disease": "", "pathway": " (sce:YCL037C)", "pathway_count": 1, "publication_count": 25, "publication_id_list": "10564276;11689685;12372297;12748633;14562095;14562106;1574125;18407956;19779198;19795423;19823750;21126336;21177495;22106047;22218487;22814378;23749301;24374639;30516470;32597660;33229814;33481703;33491328;34965436;9383048", "class_list": "", "function": "May overlap in function with tropomyosin and may be involved in organization of actin filaments. Acts as a multicopy suppressor of RHO3 mutation. RNA-binding protein which may modulate mRNA translation. Involved in heme regulation of HAP1, as a component of the high-molecular-weight complex (HMC)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 8, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 8, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 8, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 35, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "D6VQX8", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0003729 mRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0006417 regulation of translation;GO:0045892 negative regulation of DNA-templated transcription;GO:0045727 positive regulation of translation;GO:0070482 response to oxygen levels", "synthesized_glycan_count": 0, "hit_score": 3.5, "record_id": "P25567-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25573-1", "uniprot_id": "MGR1_YEAST", "mass": 47156.0, "length": 417, "protein_name": "Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR1", "gene_name": "MGR1", "organism": "Yeast", "refseq_name": "Mgr1p", "refseq_ac": "NP_009886", "gene_names_uniprotkb": "MGR1; YCL314; YCL44C", "gene_names_refseq": "MGR1", "protein_names_uniprotkb": "Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR1; Mitochondrial genome-required protein 1", "protein_names_refseq": "Mgr1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YCL044C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562095;14562106;14576278;1523890;1574125;16267274;18843051;24374639", "class_list": "", "function": "Component of the mitochondrial inner membrane i-AAA protease supercomplex required for mitochondrial inner membrane protein turnover. Together with MGR3, functions in an adapter complex that targets substrates to the i-AAA protease for degradation. Required for growth of cells lacking the mitochondrial genome., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VQX2", "ec_number_list": "", "go_molecular_function": "GO:0051787 misfolded protein binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0031942 i-AAA complex", "go_biological_process": "GO:0045041 protein import into mitochondrial intermembrane space;GO:0030163 protein catabolic process;GO:0006515 protein quality control for misfolded or incompletely synthesized proteins", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P25573-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25574-1", "uniprot_id": "EMC1_YEAST", "mass": 87181.0, "length": 760, "protein_name": "ER membrane protein complex subunit 1", "gene_name": "EMC1", "organism": "Yeast", "refseq_name": "Emc1p", "refseq_ac": "NP_009884", "gene_names_uniprotkb": "EMC1; YCL315; YCL45C", "gene_names_refseq": "EMC1", "protein_names_uniprotkb": "ER membrane protein complex subunit 1", "protein_names_refseq": "Emc1p", "tax_id": 559292, "disease": "cerebellar atrophy, visual impairment, and psychomotor retardation (Disease Ontology:DOID:0081276); intestinal cancer (Disease Ontology:DOID:10155)", "pathway": " (sce:YCL045C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562095;14562106;1523890;1574125;16847258;19325107;19756047;24374639;29809151", "class_list": "", "function": "Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins (PubMed:29809151). Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues (PubMed:29809151). Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices (PubMed:29809151). It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes. By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins (By similarity)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 8, "predicted_n_glycosites": 8, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "D6VQX1", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0072546 EMC complex;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0015914 phospholipid transport;GO:0006644 phospholipid metabolic process;GO:0034975 protein folding in endoplasmic reticulum;GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P25574-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25576-1", "uniprot_id": "POF1_YEAST", "mass": 29673.0, "length": 258, "protein_name": "Nicotinamide mononucleotide adenylyltransferase", "gene_name": "POF1", "organism": "Yeast", "refseq_name": "nicotinamide-nucleotide adenylyltransferase", "refseq_ac": "NP_009883", "gene_names_uniprotkb": "POF1; YCL47C", "gene_names_refseq": "POF1", "protein_names_uniprotkb": "Nicotinamide mononucleotide adenylyltransferase; 2.7.7.1; NMN adenylyltransferase; NMN-specific adenylyltransferase; NMNAT; Promoter of filamentation protein 1", "protein_names_refseq": "nicotinamide-nucleotide adenylyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YCL047C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562106;1574125;21460040;22204397;22814378;24374639;24759102;33491328", "class_list": "", "function": "Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Involved in the salvage pathway for NAD(+) biosynthesis via NMN (PubMed:24759102). Involved in the filamentation pathway. Suppresses the filamentation defect of a KSS1 deletion (PubMed:21460040)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQX0", "ec_number_list": "2.7.7.1;2.7.7.18", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0000309 nicotinamide-nucleotide adenylyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0036503 ERAD pathway;GO:0034355 NAD+ biosynthetic process via the salvage pathway;GO:0001403 invasive growth in response to glucose limitation;GO:0007124 pseudohyphal growth", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P25576-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25580-1", "uniprot_id": "PBN1_YEAST", "mass": 47923.0, "length": 416, "protein_name": "Protein PBN1", "gene_name": "PBN1", "organism": "Yeast", "refseq_name": "Pbn1p", "refseq_ac": "NP_009878", "gene_names_uniprotkb": "PBN1; YCL52C", "gene_names_refseq": "PBN1", "protein_names_uniprotkb": "Protein PBN1; Protease B non-derepressible protein 1", "protein_names_refseq": "Pbn1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YCL052C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562106;15635094;1574125;16418276;17322287;24374639;9090049;9649520", "class_list": "", "function": "Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Aids the autocatalytic processing of PRB1. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6VQW4", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:1990529 glycosylphosphatidylinositol-mannosyltransferase I complex", "go_biological_process": "GO:0016485 protein processing;GO:0036503 ERAD pathway;GO:0006506 GPI anchor biosynthetic process;GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P25580-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25582-1", "uniprot_id": "SPB1_YEAST", "mass": 96485.0, "length": 841, "protein_name": "27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase", "gene_name": "SPB1", "organism": "Yeast", "refseq_name": "27S pre-rRNA (guanosine2922-2'-O)-methyltransferase", "refseq_ac": "NP_009877", "gene_names_uniprotkb": "SPB1; YCL431; YCL54W", "gene_names_refseq": "SPB1", "protein_names_uniprotkb": "27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase; 2'-O-ribose RNA methyltransferase SPB1; 2.1.1.167; AdoMet-dependent rRNA methyltransferase SPB1; S-adenosyl-L-methionine-dependent methyltransferase; Suppressor of PAB1 protein 1", "protein_names_refseq": "27S pre-rRNA (guanosine2922-2'-O)-methyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YCL054W)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "10556316;10648622;12374754;1441748;14636587;15546625;1574125;17330950;17563356;18407956;19779198;19795423;19823750;21177495;23749301;24374639;30516470;33481703;33491328", "class_list": "", "function": "Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit. Specifically methylates the guanosine in position 2922 of the 25S rRNA at the stage of 27S pre-rRNA maturation. Also methylates the uridine in position 2921 in the absence of methylation of this residue guided by snoRNA snR52 at the stage of 35S pre-rRNA maturation., [UniProtKB, HAMAP, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQW3", "ec_number_list": "2.1.1.167", "go_molecular_function": "GO:0016435 rRNA (guanine) methyltransferase activity;GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity;GO:0008650 rRNA (uridine-2'-O-)-methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0030687 preribosome, large subunit precursor", "go_biological_process": "GO:0031167 rRNA methylation;GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P25582-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25586-1", "uniprot_id": "KRR1_YEAST", "mass": 37159.0, "length": 316, "protein_name": "KRR1 small subunit processome component", "gene_name": "KRR1", "organism": "Yeast", "refseq_name": "ribosome biosynthesis protein KRR1", "refseq_ac": "NP_009872", "gene_names_uniprotkb": "KRR1; YCL59C", "gene_names_refseq": "KRR1", "protein_names_uniprotkb": "KRR1 small subunit processome component; KRR-R motif-containing protein 1; Ribosomal RNA assembly protein KRR1", "protein_names_refseq": "ribosome biosynthesis protein KRR1", "tax_id": 559292, "disease": "", "pathway": " (sce:YCL059C); (R-SCE-6791226)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "11027267;11996121;14562095;14562106;15094838;15590835;1574125;17322287;24374639;8675026", "class_list": "", "function": "Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Essential for vegetative growth., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQV7", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0030688 preribosome, small subunit precursor;GO:0030686 90S preribosome;GO:0032040 small-subunit processome", "go_biological_process": "GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364 rRNA processing;GO:0042274 ribosomal small subunit biogenesis;GO:0030490 maturation of SSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P25586-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25588-1", "uniprot_id": "MRC1_YEAST", "mass": 124326.0, "length": 1096, "protein_name": "Mediator of replication checkpoint protein 1", "gene_name": "MRC1", "organism": "Yeast", "refseq_name": "chromatin-modulating protein MRC1", "refseq_ac": "NP_009871", "gene_names_uniprotkb": "MRC1; YCL60C", "gene_names_refseq": "MRC1; YCL060C", "protein_names_uniprotkb": "Mediator of replication checkpoint protein 1; DNA replication checkpoint mediator MRC1", "protein_names_refseq": "chromatin-modulating protein MRC1", "tax_id": 559292, "disease": "", "pathway": " (sce:YCL061C); (R-SCE-176187)", "pathway_count": 2, "publication_count": 27, "publication_id_list": "11715016;12865299;12944972;14562106;14690591;1574125;17287358;17330950;17563356;18407956;19515819;19684113;19779198;19795423;19823750;20190278;20702584;21177495;2169608;23749301;24374639;29371596;30516470;32597660;33229814;33481703;33491328", "class_list": "", "function": "Required for normal DNA replication. Phosphorylated in response to DNA replication stress. Phosphorylation allows it to mediate the activation of RAD53., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 68, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VQV6;P25589;P27513;P87003;Q07218;Q8NIN2", "ec_number_list": "", "go_molecular_function": "GO:0010997 anaphase-promoting complex binding;GO:0140713 histone chaperone activity", "go_cellular_component": "GO:0031298 replication fork protection complex;GO:0043596 nuclear replication fork;GO:0005634 nucleus;GO:0034399 nuclear periphery;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0000076 DNA replication checkpoint signaling;GO:0033262 regulation of nuclear cell cycle DNA replication;GO:0031509 subtelomeric heterochromatin formation;GO:0006281 DNA repair;GO:0000723 telomere maintenance", "synthesized_glycan_count": 0, "hit_score": 3.1, "record_id": "P25588-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25591-1", "uniprot_id": "VAC17_YEAST", "mass": 47843.0, "length": 423, "protein_name": "vacuole-related protein 17", "gene_name": "VAC17", "organism": "Yeast", "refseq_name": "Vac17p", "refseq_ac": "NP_009870", "gene_names_uniprotkb": "VAC17; YCL62W", "gene_names_refseq": "VAC17; YCL062W", "protein_names_uniprotkb": "vacuole-related protein 17; Vacuole-specific MYO2 receptor VAC17", "protein_names_refseq": "Vac17p", "tax_id": 559292, "disease": "", "pathway": " (sce:YCL063W)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "12594460;12642614;15684027;1574125;15821138;16824055;17699591;18804442;19779198;22814378;23749301;24374639;28495836;32597660;32916113;33481703;33491328", "class_list": "", "function": "Vacuole-specific MYO2 receptor required for vacuole inheritance. Binds simultaneously to MYO2 and to VAC8, a vacuolar membrane protein, forming a transport complex which moves the attached vacuole membrane along actin cables into the bud. Once the vacuole arrives in the bud, VAC17 is degraded, depositing the vacuole in its correct location., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 22, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQV5;P25590", "ec_number_list": "", "go_molecular_function": "GO:0043495 protein-membrane adaptor activity", "go_cellular_component": "GO:0000329 fungal-type vacuole membrane;GO:0071563 Myo2p-Vac17p-Vac8p transport complex", "go_biological_process": "GO:0000011 vacuole inheritance", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P25591-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25604-1", "uniprot_id": "STP22_YEAST", "mass": 43330.0, "length": 385, "protein_name": "Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease", "gene_name": "STP22", "organism": "Yeast", "refseq_name": "ubiquitin-binding ESCRT-I subunit protein STP22", "refseq_ac": "NP_009919", "gene_names_uniprotkb": "STP22; VPS23; YCL8C", "gene_names_refseq": "AGS1; STP22; VPL15; VPS23", "protein_names_uniprotkb": "Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease; ESCRT-I complex subunit VPS23; Vacuolar protein sorting-associated protein 23", "protein_names_refseq": "ubiquitin-binding ESCRT-I subunit protein STP22", "tax_id": 559292, "disease": "prostate cancer (Disease Ontology:DOID:10283); breast cancer (Disease Ontology:DOID:1612); cancer (Disease Ontology:DOID:162); ovarian cancer (Disease Ontology:DOID:2394); endometrial adenocarcinoma (Disease Ontology:DOID:2870); cervix carcinoma (Disease Ontology:DOID:2893); carcinoma (Disease Ontology:DOID:305); breast carcinoma (Disease Ontology:DOID:3459)", "pathway": " (sce:YCL008C)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "10207082;11208108;11511343;12844361;12900393;14562106;15044434;15086794;1574125;16615893;16615894;17215868;17442384;23749301;24374639;33491328", "class_list": "", "function": "Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association to the ESCRT-0 complex. Required for vacuolar targeting of temperature-sensitive plasma membrane proteins STE2 and CAN1., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VR04;P87010;P87279;Q86ZT3;Q8NIM6", "ec_number_list": "", "go_molecular_function": "GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005768 endosome;GO:0005829 cytosol;GO:0031902 late endosome membrane;GO:0009898 cytoplasmic side of plasma membrane;GO:0000813 ESCRT I complex", "go_biological_process": "GO:0006612 protein targeting to membrane;GO:0008333 endosome to lysosome transport;GO:0061709 reticulophagy;GO:0045324 late endosome to vacuole transport;GO:0006623 protein targeting to vacuole", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P25604-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25605-1", "uniprot_id": "ILV6_YEAST", "mass": 33987.0, "length": 309, "protein_name": "Acetolactate synthase small subunit, mitochondrial", "gene_name": "ILV6", "organism": "Yeast", "refseq_name": "acetolactate synthase regulatory subunit", "refseq_ac": "NP_009918", "gene_names_uniprotkb": "ILV6; YCL9C", "gene_names_refseq": "ILV6", "protein_names_uniprotkb": "Acetolactate synthase small subunit, mitochondrial; AHAS; ALS; Acetohydroxy-acid synthase small subunit", "protein_names_refseq": "acetolactate synthase regulatory subunit", "tax_id": 559292, "disease": "", "pathway": " (sce:YCL009C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "10213630;1304897;14562106;1574125;18407956;24374639;33481703;33491328;7483834;8972574", "class_list": "", "function": "Regulatory subunit of mitochondrial acetolactate synthase, which catalyzes the first of a series of common steps in the biosynthesis of the branched-chain amino acids. Stimulates activity of the acetolactate synthase catalytic subunit ILV2 seven- to tenfold and confers sensitivity to inhibition by valine and activation by ATP., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VR03;P87009", "ec_number_list": "", "go_molecular_function": "GO:0030234 enzyme regulator activity;GO:1990610 acetolactate synthase regulator activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0042645 mitochondrial nucleoid;GO:0005948 acetolactate synthase complex", "go_biological_process": "GO:0009082 branched-chain amino acid biosynthetic process;GO:0009099 L-valine biosynthetic process;GO:0009097 isoleucine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P25605-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25613-1", "uniprot_id": "ADY2_YEAST", "mass": 30726.0, "length": 283, "protein_name": "Accumulation of dyads protein 2", "gene_name": "ADY2", "organism": "Yeast", "refseq_name": "Ady2p", "refseq_ac": "NP_009936", "gene_names_uniprotkb": "ADY2; ATO1; YCR10C", "gene_names_refseq": "ADY2; ATO1", "protein_names_uniprotkb": "Accumulation of dyads protein 2; Ammonia transport outward protein 1", "protein_names_refseq": "Ady2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YCR010C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "11470404;12429834;14968426;1574125;1626432;16286509;16847258;17233767;17395151;17761666;24374639", "class_list": "", "function": "Transporter protein required for ammonia export and acetate uptake and resistance. Necessary for up-regulation and down-regulation of meiotic plaque (MP) component levels in a dependency on external acetate. Has a role in ascus formation., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VR19", "ec_number_list": "", "go_molecular_function": "GO:0008519 ammonium channel activity;GO:0015123 acetate transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005886 plasma membrane;GO:0005774 vacuolar membrane", "go_biological_process": "GO:0006811 monoatomic ion transport;GO:0055085 transmembrane transport;GO:0072488 ammonium transmembrane transport;GO:0051321 meiotic cell cycle;GO:0006846 acetate transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P25613-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25615-1", "uniprot_id": "DPO4_YEAST", "mass": 67527.0, "length": 582, "protein_name": "DNA polymerase IV", "gene_name": "POL4", "organism": "Yeast", "refseq_name": "DNA-directed DNA polymerase IV", "refseq_ac": "NP_009940", "gene_names_uniprotkb": "POL4; POLX; YCR14C", "gene_names_refseq": "POL4", "protein_names_uniprotkb": "DNA polymerase IV; 2.7.7.7; POL IV", "protein_names_refseq": "DNA-directed DNA polymerase IV", "tax_id": 559292, "disease": "pancreatic cancer (Disease Ontology:DOID:1793); middle cerebral artery infarction (Disease Ontology:DOID:3525); systemic lupus erythematosus (Disease Ontology:DOID:9074)", "pathway": " (sce:YCR014C); (R-SCE-110362)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "10438542;12235149;1304897;1574125;1626432;23874240;24374639;8065914;8265341", "class_list": "", "function": "Repair polymerase. Involved in gap-filling in DNA nonhomologous end joining (NHEJ) required for double-strand break repair. Seems to conduct DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Preferentially acts upon short gaps formed by the alignment of linear duplexes with complementary single-strand ends. Required for filling gaps that need removal of a 5'- or 3'-terminal mismatch, however lacks nuclease activities., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VR22", "ec_number_list": "2.7.7.7;3.1.26.4;2.7.7.49;3.4.23.-;6.5.1.1;3.1.11.-", "go_molecular_function": "GO:0003887 DNA-directed DNA polymerase activity;GO:0003677 DNA binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006284 base-excision repair;GO:0006302 double-strand break repair;GO:0006303 double-strand break repair via nonhomologous end joining", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P25615-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25618-1", "uniprot_id": "CWH43_YEAST", "mass": 107883.0, "length": 953, "protein_name": "Protein CWH43", "gene_name": "CWH43", "organism": "Yeast", "refseq_name": "Cwh43p", "refseq_ac": "NP_009943", "gene_names_uniprotkb": "CWH43; YCR17C", "gene_names_refseq": "CWH43", "protein_names_uniprotkb": "Protein CWH43; Calcofluor white hypersensitive protein", "protein_names_refseq": "Cwh43p", "tax_id": 559292, "disease": "normal pressure hydrocephalus (Disease Ontology:DOID:1572)", "pathway": " (sce:YCR017C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "11427965;1574125;16847258;17714445;17761529;18407956;21126336;23749301;24374639;33491328", "class_list": "", "function": "Involved in the maintenance of cell wall integrity. Required for the replacement of the diacylglycerol moiety by ceramides during GPI-anchor maturation., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 10, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6VR25;Q8NIM1", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane;GO:0005934 cellular bud tip;GO:0005935 cellular bud neck", "go_biological_process": "GO:0006505 GPI anchor metabolic process;GO:0006506 GPI anchor biosynthetic process;GO:0031505 fungal-type cell wall organization;GO:0071555 cell wall organization", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P25618-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25623-1", "uniprot_id": "SYP1_YEAST", "mass": 96137.0, "length": 870, "protein_name": "Suppressor of yeast profilin deletion", "gene_name": "SYP1", "organism": "Yeast", "refseq_name": "Syp1p", "refseq_ac": "NP_009959", "gene_names_uniprotkb": "SYP1; YCR29C", "gene_names_refseq": "SYP1; YCR029C-A", "protein_names_uniprotkb": "Suppressor of yeast profilin deletion", "protein_names_refseq": "Syp1p", "tax_id": 559292, "disease": "early-onset Parkinson's disease (Disease Ontology:DOID:0060894); primary immunodeficiency disease (Disease Ontology:DOID:612)", "pathway": " (sce:YCR030C)", "pathway_count": 1, "publication_count": 27, "publication_id_list": "11014808;14562106;1574125;17330950;17563356;18407956;18791237;19684113;19713939;19776351;19779198;19795423;19823750;20489023;20702584;21126336;21177495;22106047;22218487;23749301;24374639;26179915;30516470;32597660;33229814;33481703;33491328", "class_list": "", "function": "Multi-functional protein that contributes to the endocytic process, but also to events that occur at the neck during budding and/or cytokinesis. Plays a role as an endocytic adapters with membrane-tubulation activity that associates with transmembrane cargo proteins and initiates the formation of endocytic sites. Contributes to the stabilization of the nascent clathrin-coated pit. Also plays a role in late endocytosis by mediating vesiculation. Involved in the regulation of cell cycle-dependent dynamics of the septin cytoskeleton by promoting septin turnover in different cell cycle stages. May act through the RHO2 signaling pathway to repolarize cortical actin patches in profilin-deficient cells., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 13, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 13, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 13, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 62, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 2, "glyco_site_count": 13, "binding_glycan_count": 0, "secondary_ac_list": "D6VR40;P25622;Q96VH0", "ec_number_list": "", "go_molecular_function": "GO:0004857 enzyme inhibitor activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030139 endocytic vesicle;GO:0032153 cell division site;GO:0061645 endocytic patch", "go_biological_process": "GO:0006897 endocytosis;GO:0045807 positive regulation of endocytosis;GO:0032185 septin cytoskeleton organization;GO:0009826 unidimensional cell growth;GO:0000147 actin cortical patch assembly", "synthesized_glycan_count": 0, "hit_score": 4.2, "record_id": "P25623-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25635-1", "uniprot_id": "PWP2_YEAST", "mass": 103983.0, "length": 923, "protein_name": "Periodic tryptophan protein 2", "gene_name": "PWP2", "organism": "Yeast", "refseq_name": "snoRNA-binding rRNA-processing protein PWP2", "refseq_ac": "NP_009984", "gene_names_uniprotkb": "PWP2; UTP1; YCR58C", "gene_names_refseq": "PWP2; UTP1; YCR055C; YCR058C", "protein_names_uniprotkb": "Periodic tryptophan protein 2; U three protein 1; U3 small nucleolar RNA-associated protein 1; U3 snoRNA-associated protein 1", "protein_names_refseq": "snoRNA-binding rRNA-processing protein PWP2", "tax_id": 559292, "disease": "", "pathway": " (sce:YCR057C); (R-SCE-6791226)", "pathway_count": 2, "publication_count": 21, "publication_id_list": "12068309;14562106;1574125;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20190278;20702584;21126336;21177495;22218487;23749301;24374639;32597660;33481703;33491328;8804409", "class_list": "", "function": "Required for bud-site selection and cell separation. Also involved in nucleolar processing of pre-18S ribosomal RNA., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VR63;P25633;P25636", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0034388 Pwp2p-containing subcomplex of 90S preribosome;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0030686 90S preribosome", "go_biological_process": "GO:0000920 septum digestion after cytokinesis;GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0030010 establishment of cell polarity", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P25635-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25637-1", "uniprot_id": "YIH1_YEAST", "mass": 29017.0, "length": 258, "protein_name": "Protein IMPACT homolog", "gene_name": "YIH1", "organism": "Yeast", "refseq_name": "Yih1p", "refseq_ac": "NP_009985", "gene_names_uniprotkb": "YIH1; YCR59C", "gene_names_refseq": "YIH1", "protein_names_uniprotkb": "Protein IMPACT homolog", "protein_names_refseq": "Yih1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YCR059C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "14562095;14562106;15126500;1574125;15937339;17322287;21239490;22106047;22404850;24333428;24374639;33491328;8313894", "class_list": "", "function": "Translational regulator that ensures constant high levels of translation under amino acid starvation. Plays a role as a negative regulator of the GCN2 kinase activity; impairs GCN1-mediated GCN2 activation, and hence GCN2-mediated eIF-2-alpha phosphorylation in amino acid-starved cells and subsequent down-regulation of protein synthesis (PubMed:15126500, PubMed:15937339, PubMed:24333428). In normal conditions, it resides in a actin complex and has no activity (PubMed:15126500)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VR64", "ec_number_list": "", "go_molecular_function": "GO:0003785 actin monomer binding;GO:0004860 protein kinase inhibitor activity;GO:0043022 ribosome binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0001933 negative regulation of protein phosphorylation;GO:0031333 negative regulation of protein-containing complex assembly;GO:0006446 regulation of translational initiation;GO:0033673 negative regulation of kinase activity;GO:0034198 cellular response to amino acid starvation", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P25637-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25641-1", "uniprot_id": "ATG15_YEAST", "mass": 58435.0, "length": 520, "protein_name": "Putative lipase ATG15", "gene_name": "ATG15", "organism": "Yeast", "refseq_name": "triglyceride lipase ATG15", "refseq_ac": "NP_009994", "gene_names_uniprotkb": "ATG15; AUT5; CVT17; YCR68W", "gene_names_refseq": "ATG15; AUT5; CVT17", "protein_names_uniprotkb": "Putative lipase ATG15; 3.1.1.3; Autophagy-related protein 15; Cytoplasm to vacuole targeting protein 17", "protein_names_refseq": "triglyceride lipase ATG15", "tax_id": 559292, "disease": "", "pathway": " (sce:YCR068W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "11085977;11264288;11566994;12499386;14562106;1574125;18690010;21364763;21777356;22843995;24374639", "class_list": "", "function": "Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies. Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles. The intravacuolar membrane disintegration by ATG15 is critical to life span extension., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VR71;Q8NIL6", "ec_number_list": "3.1.1.3;1.1.1.101", "go_molecular_function": "GO:0004620 phospholipase activity;GO:0004806 triacylglycerol lipase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0005774 vacuolar membrane;GO:0032585 multivesicular body membrane;GO:0005773 vacuole", "go_biological_process": "GO:0006660 phosphatidylserine catabolic process;GO:0006914 autophagy;GO:0034727 piecemeal microautophagy of the nucleus;GO:0006624 vacuolar protein processing;GO:0000425 pexophagy", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P25641-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25644-1", "uniprot_id": "PAT1_YEAST", "mass": 88511.0, "length": 796, "protein_name": "Deadenylation-dependent mRNA-decapping factor PAT1", "gene_name": "PAT1", "organism": "Yeast", "refseq_name": "deadenylation-dependent mRNA-decapping factor PAT1", "refseq_ac": "NP_010002", "gene_names_uniprotkb": "PAT1; MRT1; YCR77C", "gene_names_refseq": "MRT1; PAT1", "protein_names_uniprotkb": "Deadenylation-dependent mRNA-decapping factor PAT1; DNA topoisomerase 2-associated protein PAT1; Decapping activator and translational repressor PAT1; Topoisomerase II-associated protein PAT1; mRNA turnover protein 1", "protein_names_refseq": "deadenylation-dependent mRNA-decapping factor PAT1", "tax_id": 559292, "disease": "ovarian disease (Disease Ontology:DOID:1100)", "pathway": " (sce:YCR077C); (R-SCE-430039)", "pathway_count": 2, "publication_count": 59, "publication_id_list": "10394921;10523645;10747033;10761922;10779343;10913177;11027264;11514438;11741542;11780629;11875433;12032091;12730603;12773554;14562106;15703442;1574125;16179257;16357218;16777600;17287358;17330950;17429074;17513695;17563356;17875743;18086885;18407956;18981231;19111170;19684113;19779198;19795423;19823750;19901074;20832728;21126336;21177495;21925385;22814378;23222640;23706738;23749301;23893485;24139796;24247251;24374639;25035297;30059503;30516470;32597660;33039554;33229814;33481703;33491328;34965436;7645349;8816497;8972867", "class_list": "", "function": "Activator of decapping that functions as a general and active mechanism of translational repression and required for P-body formation. First decay factor recruited to mRNA, at a time when the mRNA is still associated with translation factors. Subsequently, PAT1 recruits the hepta-heterodimer LSM1-LSM7 complex to P-bodies (PubMed:10523645, PubMed:10747033, PubMed:10761922, PubMed:10913177, PubMed:11027264, PubMed:16179257, PubMed:17429074, PubMed:17513695, PubMed:17875743, PubMed:18086885, PubMed:18981231, PubMed:24247251, PubMed:25035297, PubMed:8816497). In association with the LSM1-LSM7 complex, stabilizes the 3' terminus of mRNAs (PubMed:11514438). This association is also required for mosaic virus genomic RNA translation (PubMed:12773554). Also together with the LSM1-LSM7 complex, the LSM1-LSM7 complex binds to osmotic stress-activated mRNAs to attenuate the osmotic stress response, probably by limiting ribosome access to the mRNA and consequently translation (PubMed:30059503). Modulates the rates of mRNA-decapping that occur following deadenylation (PubMed:10523645, PubMed:10747033, PubMed:10761922, PubMed:10913177, PubMed:11027264, PubMed:16179257, PubMed:17429074, PubMed:17513695, PubMed:17875743, PubMed:18086885, PubMed:18981231, PubMed:24247251, PubMed:25035297, PubMed:8816497). Might be required for promoting the formation or the stabilization of the pre-initiation translation complexes (PubMed:10779343, PubMed:20832728). Required for 40S ribosomal subunit joining to capped and/or polyadenylated mRNA (PubMed:10779343). With other P-body components, enhances the formation of retrotransposition-competent Ty1 virus-like particles (PubMed:19901074). Structural component of the kinetochore and associates with centromeres in a NDC10-dependent manner. Involved in maintaining the structural integrity of centromeric chromatin to facilitate faithful chromosome segregation and proper kinetochore function (PubMed:10394921, PubMed:23893485, PubMed:8972867)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 4, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 4, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 4, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 24, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VR80;Q8NKJ3", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0003723 RNA binding;GO:0003729 mRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000932 P-body;GO:0000776 kinetochore;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0006397 mRNA processing;GO:0051301 cell division;GO:0042149 cellular response to glucose starvation;GO:0045947 negative regulation of translational initiation", "synthesized_glycan_count": 0, "hit_score": 6.5, "record_id": "P25644-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25646-1", "uniprot_id": "PDP2_YEAST", "mass": 49421.0, "length": 442, "protein_name": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial", "gene_name": "PTC6", "organism": "Yeast", "refseq_name": "type 2C protein phosphatase PTC6", "refseq_ac": "NP_010003", "gene_names_uniprotkb": "PTC6; AUP1; PPP2; YCR79C; YCR79W", "gene_names_refseq": "AUP1; PPP2; PTC6", "protein_names_uniprotkb": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial; 3.1.3.16; 3.1.3.43; Autophagy-related protein phosphatase 1; PDC phosphatase 2; PDP 2; PP2C-6; Phosphatase two C protein 6; Protein phosphatase 2C homolog 6; Protein phosphatase of PDH protein 2; Pyruvate dehydrogenase complex phosphatase 2", "protein_names_refseq": "type 2C protein phosphatase PTC6", "tax_id": 559292, "disease": "mild variant of maple syrup urine disease (Disease Ontology:DOID:0061205); maple syrup urine disease (Disease Ontology:DOID:9269)", "pathway": " (sce:YCR079W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562106;1574125;17002782;17166847;18180296;19795423;19823750;21177495;24374639", "class_list": "", "function": "Protein phosphatase that shows typical type 2C protein phosphatase (PP2C) activity (PubMed:17002782). Catalyzes the dephosphorylation and concomitant reactivation of the E1 alpha subunit (PDA1) of the pyruvate dehydrogenase complex (PubMed:18180296). Required for efficient mitophagy in stationary phase cells (PubMed:17166847)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VR81;Q8NIL5", "ec_number_list": "3.1.3.16;3.1.3.43;3.1.3.48", "go_molecular_function": "GO:0004741 [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005758 mitochondrial intermembrane space;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0007165 signal transduction;GO:0016236 macroautophagy;GO:0000422 autophagy of mitochondrion;GO:1901524 regulation of mitophagy", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P25646-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25648-1", "uniprot_id": "SRB8_YEAST", "mass": 166861.0, "length": 1427, "protein_name": "Mediator of RNA polymerase II transcription subunit 12", "gene_name": "SRB8", "organism": "Yeast", "refseq_name": "Srb8p", "refseq_ac": "NP_010004", "gene_names_uniprotkb": "SRB8; GIG1; MED12; NUT6; SSN5; YCR80W", "gene_names_refseq": "GIG1; MED12; NUT6; SRB8; SSN5; YCR080W", "protein_names_uniprotkb": "Mediator of RNA polymerase II transcription subunit 12; Mediator complex subunit 12; Suppressor of RNA polymerase B 8", "protein_names_refseq": "Srb8p", "tax_id": 559292, "disease": "", "pathway": " (sce:YCR081W)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "12200444;14562106;15175151;15477388;15601835;1574125;16076843;16109375;21177495;24374639;33229814;33933450;7774808", "class_list": "", "function": "Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II RPB1 at serines 2 and 5., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VR82;P25647", "ec_number_list": "", "go_molecular_function": "GO:0003713 transcription coactivator activity", "go_cellular_component": "GO:0016592 mediator complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0000411 positive regulation of transcription by galactose", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P25648-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25651-1", "uniprot_id": "CSM1_YEAST", "mass": 21751.0, "length": 190, "protein_name": "Monopolin complex subunit CSM1", "gene_name": "CSM1", "organism": "Yeast", "refseq_name": "Csm1p", "refseq_ac": "NP_010009", "gene_names_uniprotkb": "CSM1; SPO86; YCR86W", "gene_names_refseq": "CSM1", "protein_names_uniprotkb": "Monopolin complex subunit CSM1; Chromosome segregation in meiosis protein 1", "protein_names_refseq": "Csm1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YCR086W)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "11470404;11489916;12689592;14562095;14562106;15023545;1574125;16487579;17322287;18997772;24374639;33481703;33491328", "class_list": "", "function": "Component of the monopolin complex which promotes monoorientation during meiosis I, required for chromosome segregation during meiosis. Also plays a mitotic role in DNA replication., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VR86", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:1990644 microtubule site clamp", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005730 nucleolus;GO:0034506 chromosome, centromeric core domain;GO:0072686 mitotic spindle;GO:0033551 monopolin complex", "go_biological_process": "GO:0051315 attachment of mitotic spindle microtubules to kinetochore;GO:0051455 spindle attachment to meiosis I kinetochore;GO:0045143 homologous chromosome segregation;GO:0051754 meiotic sister chromatid cohesion, centromeric;GO:0045132 meiotic chromosome segregation", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P25651-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25653-1", "uniprot_id": "FIG2_YEAST", "mass": 166036.0, "length": 1609, "protein_name": "Factor-induced gene 2 protein", "gene_name": "FIG2", "organism": "Yeast", "refseq_name": "Fig2p", "refseq_ac": "NP_010013", "gene_names_uniprotkb": "FIG2; YCR1102; YCR89W", "gene_names_refseq": "FIG2", "protein_names_uniprotkb": "Factor-induced gene 2 protein; Cell wall adhesin FIG2", "protein_names_refseq": "Fig2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YCR089W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "11027318;12455698;12455701;1523889;1574125;19756047;24374639;9023939;9456310", "class_list": "", "function": "Required for efficient mating. Plays a role in maintenance of cell wall integrity during mating. Important for mating cell projection shape and conjugation bridge diameter. Plays a role in cell fusion and nuclear migration., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 16, "predicted_n_glycosites": 15, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 16, "binding_glycan_count": 0, "secondary_ac_list": "D6VR89", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0071944 cell periphery;GO:0005937 mating projection;GO:0009277 fungal-type cell wall;GO:0098552 side of membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0008360 regulation of cell shape;GO:0019236 response to pheromone;GO:0000753 cell morphogenesis involved in conjugation with cellular fusion;GO:0000755 cytogamy", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P25653-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25656-1", "uniprot_id": "CDC50_YEAST", "mass": 44982.0, "length": 391, "protein_name": "Phospholipid-transporting ATPase accessory subunit CDC50", "gene_name": "CDC50", "organism": "Yeast", "refseq_name": "aminophospholipid translocase regulatory protein CDC50", "refseq_ac": "NP_010018", "gene_names_uniprotkb": "CDC50; SWA4; YCR94W", "gene_names_refseq": "CDC50", "protein_names_uniprotkb": "Phospholipid-transporting ATPase accessory subunit CDC50; Cell division control protein 50", "protein_names_refseq": "aminophospholipid translocase regulatory protein CDC50", "tax_id": 559292, "disease": "", "pathway": " (sce:YCR094W); (R-SCE-6798695)", "pathway_count": 2, "publication_count": 16, "publication_id_list": "11180453;12589066;14562106;15090616;1574125;16847258;16956384;19411703;21212072;22791719;24374639;25393116;28302728;31243363;31515475;34023399", "class_list": "", "function": "Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of phosphatidylserine and small amounts of ethanolamine from the lumen to the cytosolic leaflet of the trans-Golgi network and ensures the maintenance of asymmetric distribution of phospholipids (PubMed:16956384, PubMed:19411703, PubMed:22791719, PubMed:25393116, PubMed:28302728, PubMed:31243363, PubMed:31515475, PubMed:34023399). Required for the formation of transport vesicles from endosomes (PubMed:21212072)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 4, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 4, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 4, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6VR94", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0031902 late endosome membrane", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006897 endocytosis;GO:0045332 phospholipid translocation;GO:0042147 retrograde transport, endosome to Golgi;GO:0051666 actin cortical patch localization", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P25656-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25719-1", "uniprot_id": "CYPC_YEAST", "mass": 19919.0, "length": 182, "protein_name": "Peptidyl-prolyl cis-trans isomerase C, mitochondrial", "gene_name": "CPR3", "organism": "Yeast", "refseq_name": "peptidylprolyl isomerase CPR3", "refseq_ac": "NP_013633", "gene_names_uniprotkb": "CPR3; CYP3", "gene_names_refseq": "CPR3; CYP3", "protein_names_uniprotkb": "Peptidyl-prolyl cis-trans isomerase C, mitochondrial; 5.2.1.8; Cyclophilin C; PPI-III; PPIase C; Rotamase C", "protein_names_refseq": "peptidylprolyl isomerase CPR3", "tax_id": 559292, "disease": "childhood-onset asthma (Disease Ontology:DOID:0080815); Bell's palsy (Disease Ontology:DOID:12506); aggressive periodontitis (Disease Ontology:DOID:1474); epilepsy (Disease Ontology:DOID:1826); cholangiocarcinoma (Disease Ontology:DOID:4947); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); nasopharynx carcinoma (Disease Ontology:DOID:9261)", "pathway": " (sce:YML078W); (R-SCE-6798695)", "pathway_count": 2, "publication_count": 16, "publication_id_list": "10025965;1454795;14562095;14562106;14576278;1547957;17322287;17330950;18407956;23749301;24374639;33481703;33491328;7603990;8431466;9169872", "class_list": "", "function": "PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. This isozyme is required for growth on lactate at high temperature., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0K5", "ec_number_list": "2.7.1.40;5.4.2.11;2.7.1.1;4.2.1.24;3.6.4.13;2.4.1.1;3.4.23.25;3.6.4.10;5.3.1.9;5.1.3.-;5.2.1.8;1.11.1.6;3.5.4.6;2.7.1.11;2.7.1.2;1.1.1.42;3.4.25.1;3.6.4.6;3.6.5.-;2.7.11.24;3.6.4.12;5.4.2.2;1.11.1.24;2.7.4.6;2.4.1.186;1.1.1.205;2.7.1.35;3.4.19.12;2.4.2.7;5.4.2.7;2.3.2.26;2.7.11.23;2.4.2.1;2.7.1.59;3.5.4.5;3.4.11.-;3.3.2.10", "go_molecular_function": "GO:0016018 cyclosporin A binding;GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006915 apoptotic process;GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P25719-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25808-1", "uniprot_id": "SPB4_YEAST", "mass": 69422.0, "length": 606, "protein_name": "ATP-dependent rRNA helicase SPB4", "gene_name": "SPB4", "organism": "Yeast", "refseq_name": "ATP-dependent RNA helicase SPB4", "refseq_ac": "NP_116654", "gene_names_uniprotkb": "SPB4", "gene_names_refseq": "SPB4", "protein_names_uniprotkb": "ATP-dependent rRNA helicase SPB4; 3.6.4.13; Suppressor of PAB1 protein 4", "protein_names_refseq": "ATP-dependent RNA helicase SPB4", "tax_id": 559292, "disease": "", "pathway": " (sce:YFL002C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "14562095;14562106;17287358;21825077;22735702;23874617;2408148;24374639;25579579;7670463;8789262;9769101", "class_list": "", "function": "ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits (PubMed:2408148, PubMed:25579579). Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA (PubMed:21825077). Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5.8S rRNAs through the processing of pre-rRNAs at sites C1 and C2 (PubMed:9769101). Also required for recruitment of NOG2 to pre-ribosomes (PubMed:22735702)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTM9", "ec_number_list": "3.6.4.13;5.6.2.3;3.6.4.10;3.6.-.-;5.6.2.4;3.6.4.-;5.6.1.4;3.6.4.12;3.6.4.6;5.6.2.5;3.6.1.-;2.3.2.27;3.1.-.-;3.4.24.-;3.6.5.-;2.7.4.3;2.7.11.1;7.2.2.-", "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0030687 preribosome, large subunit precursor;GO:0030686 90S preribosome", "go_biological_process": "GO:0000027 ribosomal large subunit assembly;GO:0000470 maturation of LSU-rRNA;GO:1902626 assembly of large subunit precursor of preribosome", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P25808-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25846-1", "uniprot_id": "MSH1_YEAST", "mass": 109409.0, "length": 959, "protein_name": "DNA mismatch repair protein MSH1, mitochondrial", "gene_name": "MSH1", "organism": "Yeast", "refseq_name": "mismatch repair ATPase MSH1", "refseq_ac": "NP_011988", "gene_names_uniprotkb": "MSH1", "gene_names_refseq": "MSH1", "protein_names_uniprotkb": "DNA mismatch repair protein MSH1, mitochondrial; MutS protein homolog 1", "protein_names_refseq": "mismatch repair ATPase MSH1", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR120W)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "11862493;1334021;14562095;14562106;14576278;1459447;15010316;15611870;16337661;19795423;19823750;24374639;33229814;33491328;7961998;7961999;8091229;9726974", "class_list": "", "function": "Important for mitochondrial DNA (mtDNA) stability and repair. Recognizes and binds to base-base and small insertion-deletion mismatches in mtDNA. ATP binding and hydrolysis is crucial for function. Binding to a mismatched base pair attenuates ATP hydrolysis. Also involved in proper sorting of mtDNA during mtDNA transmission., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 4, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D3DL70", "ec_number_list": "", "go_molecular_function": "GO:0032139 dinucleotide insertion or deletion binding;GO:0005524 ATP binding;GO:0003690 double-stranded DNA binding;GO:0008094 ATP-dependent activity, acting on DNA;GO:0032137 guanine/thymine mispair binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion", "go_biological_process": "GO:0006281 DNA repair;GO:0006298 mismatch repair;GO:0007005 mitochondrion organization;GO:0043504 mitochondrial DNA repair", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P25846-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25847-1", "uniprot_id": "MSH2_YEAST", "mass": 108884.0, "length": 964, "protein_name": "DNA mismatch repair protein MSH2", "gene_name": "MSH2", "organism": "Yeast", "refseq_name": "mismatch repair ATPase MSH2", "refseq_ac": "NP_014551", "gene_names_uniprotkb": "MSH2; O0935", "gene_names_refseq": "MSH2; PMS5", "protein_names_uniprotkb": "DNA mismatch repair protein MSH2; MutS protein homolog 2", "protein_names_refseq": "mismatch repair ATPase MSH2", "tax_id": 559292, "disease": "Muir-Torre syndrome (Disease Ontology:DOID:0050465); colitis (Disease Ontology:DOID:0060180); hereditary nonpolyposis colorectal cancer type 8 (Disease Ontology:DOID:0070270); Lynch syndrome 1 (Disease Ontology:DOID:0070271); mismatch repair cancer syndrome (Disease Ontology:DOID:0112182); prostate cancer (Disease Ontology:DOID:10283); urinary bladder cancer (Disease Ontology:DOID:11054); lung cancer (Disease Ontology:DOID:1324); breast cancer (Disease Ontology:DOID:1612); cancer (Disease Ontology:DOID:162); colon cancer (Disease Ontology:DOID:219); ovarian cancer (Disease Ontology:DOID:2394); transitional cell carcinoma (Disease Ontology:DOID:2671); laryngeal squamous cell carcinoma (Disease Ontology:DOID:2876); osteosarcoma (Disease Ontology:DOID:3347); breast carcinoma (Disease Ontology:DOID:3459); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); Lynch syndrome (Disease Ontology:DOID:3883); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); renal cell carcinoma (Disease Ontology:DOID:4450); primary ovarian insufficiency (Disease Ontology:DOID:5426); cervix uteri carcinoma in situ (Disease Ontology:DOID:8991); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (sce:YOL090W); (R-SCE-5358565); (R-SCE-5358606)", "pathway_count": 3, "publication_count": 45, "publication_id_list": "10066781;10077621;10469597;10480869;10518225;10523644;11005803;11237611;11555625;11641390;12435741;12509278;12820877;12875840;1334021;14562095;14562106;1459447;15513922;15746000;15811858;16214425;16337600;16600868;16702432;16781730;17157869;17636021;18471978;21177495;24374639;33491328;8066446;8533473;8600025;8805366;8816473;8858149;9111357;9169874;9256462;9368761;9545323;9770499;9819445", "class_list": "", "function": "Component of the post-replicative DNA mismatch repair system (MMR). Forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer), which bind to DNA mismatches thereby initiating DNA repair. MSH2 seems to act as a scaffold for the other MutS homologs that provide substrate-binding and substrate specificity. When bound, heterodimers bend the DNA helix and shield approximately 20 base pairs. MutS alpha acts mainly to repair base-base and single insertion-deletion mismatches that occur during replication, but can also repair longer insertion-deletion loops (IDLs), although with decreasing efficiency as the size of the extrahelical loop increases. MutS beta acts mainly to repair IDLs from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches. After mismatch binding, MutS alpha or beta form a ternary complex with a MutL heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. Both subunits bind ATP, but with differing affinities, and their ATPase kinetics are also very different. MSH6 binds and hydrolyzes ATP rapidly, whereas MSH2 catalyzes ATP at a substantially slower rate. Binding to a mismatched base pair suppresses MSH6-catalyzed ATP hydrolysis, but not the activity of MSH2. ATP binding to both subunits is necessary to trigger a change in MutS alpha interaction with mismatched DNA, converting MutS alpha into a sliding clamp capable of hydrolysis-independent movement along DNA, and also facilitates formation of ternary complexes containing MutS and MutL proteins and the mismatch. MutS beta also has a role in regulation of heteroduplex formation during mitotic and meiotic recombination. MutS beta binds to DNA flap structures predicted to form during recombination, and is required for 3' non-homologous tail removal (NHTR). MutS beta-binding alters the DNA conformation of its substrate at the ds/ssDNA junction and may facilitate its recognition and/or cleavage by the downstream nucleotide excision repair (NER) RAD1-RAD10 endonuclease., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 33, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 24, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1X8;Q12423", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0000400 four-way junction DNA binding;GO:0030983 mismatched DNA binding;GO:0000406 double-strand/single-strand DNA junction binding", "go_cellular_component": "GO:0032301 MutSalpha complex;GO:0005634 nucleus;GO:0000228 nuclear chromosome;GO:0032302 MutSbeta complex", "go_biological_process": "GO:0006312 mitotic recombination;GO:0000710 meiotic mismatch repair;GO:0006310 DNA recombination;GO:0006298 mismatch repair;GO:0036297 interstrand cross-link repair", "synthesized_glycan_count": 0, "hit_score": 4.6, "record_id": "P25847-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P26188-1", "uniprot_id": "MGMT_YEAST", "mass": 21499.0, "length": 188, "protein_name": "Methylated-DNA--protein-cysteine methyltransferase", "gene_name": "MGT1", "organism": "Yeast", "refseq_name": "methylated-DNA--protein-cysteine methyltransferase", "refseq_ac": "NP_010081", "gene_names_uniprotkb": "MGT1; D1204", "gene_names_refseq": "MGT1", "protein_names_uniprotkb": "Methylated-DNA--protein-cysteine methyltransferase; 2.1.1.63; 6-O-methylguanine-DNA methyltransferase; DNA repair MTase; MGMT; O-6-methylguanine-DNA-alkyltransferase", "protein_names_refseq": "methylated-DNA--protein-cysteine methyltransferase", "tax_id": 559292, "disease": "urinary bladder cancer (Disease Ontology:DOID:11054); breast cancer (Disease Ontology:DOID:1612); pancreatic cancer (Disease Ontology:DOID:1793); pancreatic endocrine carcinoma (Disease Ontology:DOID:1798); melanoma (Disease Ontology:DOID:1909); colon adenocarcinoma (Disease Ontology:DOID:234); cervix carcinoma (Disease Ontology:DOID:2893); granulosa cell tumor (Disease Ontology:DOID:2999); glioblastoma (Disease Ontology:DOID:3068); oligodendroglioma (Disease Ontology:DOID:3181); pancreatic ductal carcinoma (Disease Ontology:DOID:3587); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); cholangiocarcinoma (Disease Ontology:DOID:4947); gastrinoma (Disease Ontology:DOID:5577); retinoblastoma (Disease Ontology:DOID:768)", "pathway": " (sce:YDL200C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "12748633;12775844;1641326;1993655;2065659;2403555;24374639;7549791;8896272;9046097;9169867", "class_list": "", "function": "Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. Prefers double-stranded DNA over single-stranded DNA as substrate., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 15, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRF4", "ec_number_list": "2.1.1.63", "go_molecular_function": "GO:0003908 methylated-DNA-[protein]-cysteine S-methyltransferase activity;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005777 peroxisome", "go_biological_process": "GO:0006307 DNA alkylation repair;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P26188-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P26263-1", "uniprot_id": "PDC6_YEAST", "mass": 61580.0, "length": 563, "protein_name": "Pyruvate decarboxylase isozyme 3", "gene_name": "PDC6", "organism": "Yeast", "refseq_name": "indolepyruvate decarboxylase 6", "refseq_ac": "NP_011601", "gene_names_uniprotkb": "PDC6", "gene_names_refseq": "PDC6", "protein_names_uniprotkb": "Pyruvate decarboxylase isozyme 3; 2ODC; 4.1.1.-; 4.1.1.43; 4.1.1.72; 4.1.1.74; Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase", "protein_names_refseq": "indolepyruvate decarboxylase 6", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR087C)", "pathway_count": 1, "publication_count": 21, "publication_id_list": "10234824;10753893;11141278;12499363;12902239;14562095;14562106;1744053;18407956;21177495;22904058;23642236;23749301;24374639;33491328;6383467;9169869;9341119;9655908;9655924;9748245", "class_list": "", "function": "Minor of three pyruvate decarboxylases (PDC1, PDC5, PDC6) implicated in the nonoxidative conversion of pyruvate to acetaldehyde and carbon dioxide during alcoholic fermentation. Most of the produced acetaldehyde is subsequently reduced to ethanol, but some is required for cytosolic acetyl-CoA production for biosynthetic pathways. The enzyme is also one of five 2-oxo acid decarboxylases (PDC1, PDC5, PDC6, ARO10, and THI3) able to decarboxylate more complex 2-oxo acids (alpha-keto-acids) than pyruvate, which seem mainly involved in amino acid catabolism. Here the enzyme catalyzes the decarboxylation of amino acids, which, in a first step, have been transaminated to the corresponding 2-oxo acids. In a third step, the resulting aldehydes are reduced to alcohols, collectively referred to as fusel oils or alcohols. Its preferred substrates are the transaminated amino acids derived from threonine (2-oxobutanoate), norvaline (2-oxopentanoate), valine (3-methyl-2-oxobutanoate, also alpha-keto-isovalerate), isoleucine ((3S)-3-methyl-2-oxopentanoate, also alpha-keto-beta-methylvalerate), phenylalanine (phenylpyruvate), and tryptophan (3-(indol-3-yl)pyruvate), whereas transaminated leucine is no substrate. In a side-reaction the carbanionic intermediate (or active aldehyde) generated by decarboxylation or by activation of an aldehyde can react with an aldehyde via condensation (or carboligation) yielding a 2-hydroxy ketone, collectively called acyloins. The expression level of this protein in the presence of fermentable carbon sources is so low that it cannot compensate for the other two pyruvate decarboxylases to sustain fermentation., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUL9", "ec_number_list": "4.1.1.-;4.1.1.43;4.1.1.72;4.1.1.74;4.1.1.80", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0030976 thiamine pyrophosphate binding;GO:0004737 pyruvate decarboxylase activity;GO:0047433 branched-chain-2-oxoacid decarboxylase activity;GO:0047434 indolepyruvate decarboxylase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006569 L-tryptophan catabolic process;GO:0009083 branched-chain amino acid catabolic process;GO:0006559 L-phenylalanine catabolic process;GO:0006067 ethanol metabolic process;GO:0000949 aromatic amino acid family catabolic process to alcohol via Ehrlich pathway", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P26263-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P26309-1", "uniprot_id": "CDC20_YEAST", "mass": 67360.0, "length": 610, "protein_name": "APC/C activator protein CDC20", "gene_name": "CDC20", "organism": "Yeast", "refseq_name": "ubiquitin-protein transferase activating protein CDC20", "refseq_ac": "NP_011399", "gene_names_uniprotkb": "CDC20", "gene_names_refseq": "CDC20; PAC5", "protein_names_uniprotkb": "APC/C activator protein CDC20; Cell division control protein 20", "protein_names_refseq": "ubiquitin-protein transferase activating protein CDC20", "tax_id": 559292, "disease": "melanoma (Disease Ontology:DOID:1909)", "pathway": " (sce:YGL116W); (R-SCE-141405); (R-SCE-141430); (R-SCE-983168)", "pathway_count": 4, "publication_count": 20, "publication_id_list": "10704439;11553328;11562348;11566880;12152084;12456658;14562095;14574415;14743219;15198982;15879521;18407956;1922065;24374639;33481703;33491328;9169869;9461437;9501986;9651679", "class_list": "", "function": "Activator protein that regulates the ubiquitin ligase activity and substrate specificity of the anaphase promoting complex/cyclosome (APC/C). At the metaphase-to-anaphase transition, recognizes and binds proteins containing a D-box including the B-type cyclins CLB2 and CLB5, HSL1 and securin PDS1, and recruits them in a C-box-dependent manner to the APC/C for ubiquitination and subsequent proteolysis. Required for sister chromatid separation and disassembly of the mitotic spindle. Target of the spindle checkpoint pathway through participation in the mitotic checkpoint complex (MCC) and the MAD2-CDC20 subcomplex. MCC and presumably the MAD2-CDC20 subcomplex inhibit the ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) by preventing its activation by CDC20 until proper attachment of all chromosomes to the spindle., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VU31", "ec_number_list": "", "go_molecular_function": "GO:0010997 anaphase-promoting complex binding;GO:1990757 ubiquitin ligase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005680 anaphase-promoting complex;GO:0034399 nuclear periphery;GO:0033597 mitotic checkpoint complex", "go_biological_process": "GO:0051301 cell division;GO:0007346 regulation of mitotic cell cycle;GO:0016567 protein ubiquitination;GO:0031398 positive regulation of protein ubiquitination;GO:0007094 mitotic spindle assembly checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P26309-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P26364-1", "uniprot_id": "KAD3_YEAST", "mass": 25194.0, "length": 225, "protein_name": "GTP:AMP phosphotransferase, mitochondrial", "gene_name": "ADK2", "organism": "Yeast", "refseq_name": "adenylate kinase ADK2", "refseq_ac": "NP_011097", "gene_names_uniprotkb": "ADK2; AKY3; PAK3", "gene_names_refseq": "ADK2; AKY3; PAK3", "protein_names_uniprotkb": "GTP:AMP phosphotransferase, mitochondrial; 2.7.4.10; AK 3; Adenylate kinase 3", "protein_names_refseq": "adenylate kinase ADK2", "tax_id": 559292, "disease": "chronic lymphocytic leukemia (Disease Ontology:DOID:1040); acute kidney tubular necrosis (Disease Ontology:DOID:12556); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (sce:YER170W); (R-SCE-499943); (R-SCE-983231)", "pathway_count": 3, "publication_count": 8, "publication_id_list": "14562106;15753074;1587477;1620094;17322287;24374639;8537371;9169868", "class_list": "", "function": "Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. Does not accept ATP as phosphate donor., [UniProtKB, HAMAP, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DM78", "ec_number_list": "2.7.4.10", "go_molecular_function": "GO:0004017 AMP kinase activity;GO:0046899 nucleoside triphosphate adenylate kinase activity;GO:0005524 ATP binding;GO:0005525 GTP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006172 ADP biosynthetic process;GO:0046033 AMP metabolic process;GO:0046041 ITP metabolic process;GO:0009117 nucleotide metabolic process;GO:0046039 GTP metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P26364-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P26370-1", "uniprot_id": "UGA3_YEAST", "mass": 61224.0, "length": 528, "protein_name": "Transcriptional activator protein UGA3", "gene_name": "UGA3", "organism": "Yeast", "refseq_name": "Uga3p", "refseq_ac": "NP_010111", "gene_names_uniprotkb": "UGA3", "gene_names_refseq": "UGA3", "protein_names_uniprotkb": "Transcriptional activator protein UGA3", "protein_names_refseq": "Uga3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL170W)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562106;2109179;24374639;33491328;9169867", "class_list": "", "function": "GABA-dependent positive regulation of genes required for catabolism of GABA (UGA4, UGA1, and UGA2)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRI1", "ec_number_list": "", "go_molecular_function": "GO:0001010 RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity;GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000976 transcription cis-regulatory region binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0009450 gamma-aminobutyric acid catabolic process;GO:0019740 nitrogen utilization", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P26370-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P26448-1", "uniprot_id": "BUB2_YEAST", "mass": 35028.0, "length": 306, "protein_name": "Mitotic check point protein BUB2", "gene_name": "BUB2", "organism": "Yeast", "refseq_name": "Bub2p", "refseq_ac": "NP_013771", "gene_names_uniprotkb": "BUB2; YM9796.08C", "gene_names_refseq": "BUB2; PAC7", "protein_names_uniprotkb": "Mitotic check point protein BUB2; Cell cycle arrest protein BUB2", "protein_names_refseq": "Bub2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR055C)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "11493673;1651171;24374639;9169872", "class_list": "", "function": "Part of a checkpoint which monitors spindle integrity and prevents premature exit from mitosis. This cell-cycle arrest depends upon inhibition of the GTP-binding protein TEM1 by the BFA1/BUB2 complex., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZN0", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000922 spindle pole;GO:0005816 spindle pole body;GO:1990334 Bfa1-Bub2 complex;GO:0044732 mitotic spindle pole body", "go_biological_process": "GO:0051301 cell division;GO:0031030 negative regulation of septation initiation signaling;GO:1902543 negative regulation of protein localization to mitotic spindle pole body;GO:0031578 mitotic spindle orientation checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P26448-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P26449-1", "uniprot_id": "BUB3_YEAST", "mass": 38445.0, "length": 341, "protein_name": "Spindle assembly checkpoint protein BUB3", "gene_name": "BUB3", "organism": "Yeast", "refseq_name": "Bub3p", "refseq_ac": "NP_014669", "gene_names_uniprotkb": "BUB3; OR26.16", "gene_names_refseq": "BUB3; PAC9", "protein_names_uniprotkb": "Spindle assembly checkpoint protein BUB3; Cell cycle arrest protein BUB3", "protein_names_refseq": "Bub3p", "tax_id": 559292, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (sce:YOR026W); (R-SCE-141430)", "pathway_count": 2, "publication_count": 12, "publication_id_list": "10837255;11726501;14562106;15544799;15644329;15879521;1651171;17227844;24066227;24374639;7969164;9169874", "class_list": "", "function": "Involved in mitotic spindle assembly checkpoint signaling, a process that delays anaphase until chromosomes are bioriented on the spindle, and in the repair of incorrect mitotic kinetochore-spindle microtubule attachments (PubMed:15879521, PubMed:24066227). Component of the mitotic checkpoint complex (MCC) which inhibits the ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) by preventing its activation by CDC20 (PubMed:15879521)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 14, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W292", "ec_number_list": "", "go_molecular_function": "GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0000776 kinetochore;GO:0033597 mitotic checkpoint complex;GO:1990298 bub1-bub3 complex", "go_biological_process": "GO:0044774 mitotic DNA integrity checkpoint signaling;GO:0007094 mitotic spindle assembly checkpoint signaling;GO:1902499 positive regulation of protein autoubiquitination", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P26449-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P26570-1", "uniprot_id": "PPZ1_YEAST", "mass": 77491.0, "length": 692, "protein_name": "Serine/threonine-protein phosphatase PP-Z1", "gene_name": "PPZ1", "organism": "Yeast", "refseq_name": "salt homeostasis regulator", "refseq_ac": "NP_013696", "gene_names_uniprotkb": "PPZ1; YM9571.02C", "gene_names_refseq": "PPZ1", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase PP-Z1; 3.1.3.16", "protein_names_refseq": "salt homeostasis regulator", "tax_id": 559292, "disease": "", "pathway": " (sce:YML016C)", "pathway_count": 1, "publication_count": 24, "publication_id_list": "1318299;14562106;15192104;1647215;17330950;18407956;19684113;19779198;19795423;19823750;21177495;2166691;23749301;24374639;30516470;31208443;32597660;32973189;33481703;33491328;34965436;8396031;9169872;9636153", "class_list": "", "function": "Essential for the maintenance of cell size and integrity in response to osmotic stress., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 58, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VZF8;Q00979", "ec_number_list": "3.1.3.16;3.1.3.43;3.1.3.48", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006883 intracellular sodium ion homeostasis;GO:0008104 intracellular protein localization", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "P26570-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P26754-1", "uniprot_id": "RFA2_YEAST", "mass": 29936.0, "length": 273, "protein_name": "Replication factor A protein 2", "gene_name": "RFA2", "organism": "Yeast", "refseq_name": "Rfa2p", "refseq_ac": "NP_014087", "gene_names_uniprotkb": "RFA2; BUF1; N0368", "gene_names_refseq": "BUF1; RFA2; RPA2; RPA32", "protein_names_uniprotkb": "Replication factor A protein 2; DNA-binding protein BUF1; RF-A protein 2; Replication protein A 36 kDa subunit", "protein_names_refseq": "Rfa2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL312W); (R-SCE-176187); (R-SCE-6782135); (R-SCE-6782210); (R-SCE-68962)", "pathway_count": 5, "publication_count": 28, "publication_id_list": "14562106;15494305;15665377;16118184;16294044;17137646;17287358;17330950;17563356;18407956;1885001;19779198;19795423;19823750;20190278;20702584;21126336;2200738;22218487;23749301;24374639;25595672;32597660;33481703;33491328;7502583;8355713;9169873", "class_list": "", "function": "Binds to single-stranded sequences participating in DNA replication in addition to those mediating transcriptional repression (URS1) and activation (CAR1). Stimulates the activity of a cognate strand exchange protein (SEP1). It cooperates with T-AG and DNA topoisomerase I to unwind template DNA containing the simian virus 40 origin of DNA replication., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 23, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0N3;P38905", "ec_number_list": "", "go_molecular_function": "GO:0042162 telomeric DNA binding;GO:0003690 double-stranded DNA binding;GO:0043565 sequence-specific DNA binding;GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0035861 site of double-strand break;GO:0005662 DNA replication factor A complex;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0006312 mitotic recombination;GO:0010833 telomere maintenance via telomere lengthening;GO:0006281 DNA repair;GO:0000723 telomere maintenance;GO:0006260 DNA replication", "synthesized_glycan_count": 0, "hit_score": 2.9, "record_id": "P26754-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P26755-1", "uniprot_id": "RFA3_YEAST", "mass": 13816.0, "length": 122, "protein_name": "Replication factor A protein 3", "gene_name": "RFA3", "organism": "Yeast", "refseq_name": "Rfa3p", "refseq_ac": "NP_012362", "gene_names_uniprotkb": "RFA3; J0506", "gene_names_refseq": "RFA3; RPA14; RPA3", "protein_names_uniprotkb": "Replication factor A protein 3; RF-A; Replication protein A 13 kDa subunit", "protein_names_refseq": "Rfa3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL173C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562106;17322287;1885001;20190278;24374639;33491328;8221926;8641269", "class_list": "", "function": "As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism (By similarity). Stimulates the activity of a cognate strand exchange protein (SEP1)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VW15", "ec_number_list": "", "go_molecular_function": "GO:0003690 double-stranded DNA binding;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0005662 DNA replication factor A complex;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0006312 mitotic recombination;GO:0010833 telomere maintenance via telomere lengthening;GO:0006281 DNA repair;GO:0000723 telomere maintenance;GO:0006260 DNA replication", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P26755-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P26783-1", "uniprot_id": "RS5_YEAST", "mass": 25039.0, "length": 225, "protein_name": "Small ribosomal subunit protein uS7", "gene_name": "RPS5", "organism": "Yeast", "refseq_name": "40S ribosomal protein uS7 RPS5", "refseq_ac": "NP_012657", "gene_names_uniprotkb": "RPS5; J2045; RPS2", "gene_names_refseq": "RPS5", "protein_names_uniprotkb": "Small ribosomal subunit protein uS7; 40S ribosomal protein S5; RP14; S2; YS8", "protein_names_refseq": "40S ribosomal protein uS7 RPS5", "tax_id": 559292, "disease": "intrinsic cardiomyopathy (Disease Ontology:DOID:0060036)", "pathway": " (sce:YJR123W); (R-SCE-156827); (R-SCE-1799339); (R-SCE-6791226); (R-SCE-72649); (R-SCE-72689); (R-SCE-72695); (R-SCE-72702); (R-SCE-72706); (R-SCE-975956); (R-SCE-975957); (R-SCE-9954714)", "pathway_count": 12, "publication_count": 22, "publication_id_list": "10601260;11701127;14976550;1544921;17115051;17322287;18407956;19795423;19823750;21109664;22096102;22106047;23749301;24374639;24524803;29352143;32597660;33481703;33491328;8524651;8641269;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWU2", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0019843 rRNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005840 ribosome;GO:0030686 90S preribosome;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0000054 ribosomal subunit export from nucleus;GO:0006412 translation;GO:0002181 cytoplasmic translation;GO:0030490 maturation of SSU-rRNA;GO:0006450 regulation of translational fidelity", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "P26783-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P26784-1", "uniprot_id": "RL16A_YEAST", "mass": 22201.0, "length": 199, "protein_name": "Large ribosomal subunit protein uL13A", "gene_name": "RPL16A", "organism": "Yeast", "refseq_name": "60S ribosomal protein uL13 RPL16A", "refseq_ac": "NP_012133", "gene_names_uniprotkb": "RPL16A; RPL13; RPL21A", "gene_names_refseq": "RPL13; RPL16A", "protein_names_uniprotkb": "Large ribosomal subunit protein uL13A; 60S ribosomal protein L16-A; L13a; L21; RP22; YL15", "protein_names_refseq": "60S ribosomal protein uL13 RPL16A", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL133C); (R-SCE-156827); (R-SCE-1799339); (R-SCE-72689); (R-SCE-72706); (R-SCE-975956); (R-SCE-975957); (R-SCE-9954709); (R-SCE-9954714)", "pathway_count": 9, "publication_count": 18, "publication_id_list": "11701127;14562095;14562106;14976550;1544921;20702584;21109664;22096102;22106047;22814378;23749301;24374639;24524803;32597660;33481703;33491328;9169870;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVF4", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0003729 mRNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005730 nucleolus;GO:0005829 cytosol;GO:0005840 ribosome;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0017148 negative regulation of translation;GO:0002181 cytoplasmic translation;GO:0000470 maturation of LSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P26784-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P26785-1", "uniprot_id": "RL16B_YEAST", "mass": 22249.0, "length": 198, "protein_name": "Large ribosomal subunit protein uL13B", "gene_name": "RPL16B", "organism": "Yeast", "refseq_name": "60S ribosomal protein uL13 RPL16B", "refseq_ac": "NP_014330", "gene_names_uniprotkb": "RPL16B; N2377; RP23; RPL21B", "gene_names_refseq": "RP23; RPL16B", "protein_names_uniprotkb": "Large ribosomal subunit protein uL13B; 60S ribosomal protein L16-B; L21; RP23; YL15", "protein_names_refseq": "60S ribosomal protein uL13 RPL16B", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL069C)", "pathway_count": 1, "publication_count": 27, "publication_id_list": "10601260;1544921;15665377;17287358;17330950;17563356;18407956;19779198;19795423;19823750;20702584;21126336;21177495;22096102;22106047;22218487;22814378;23749301;24374639;24524803;30516470;32597660;33481703;33491328;8701611;9169873;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1B0", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0003729 mRNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005730 nucleolus;GO:0005829 cytosol;GO:0005840 ribosome;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0017148 negative regulation of translation;GO:0002181 cytoplasmic translation;GO:0000470 maturation of LSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 2.8, "record_id": "P26785-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P26786-1", "uniprot_id": "RS7A_YEAST", "mass": 21622.0, "length": 190, "protein_name": "Small ribosomal subunit protein eS7A", "gene_name": "RPS7A", "organism": "Yeast", "refseq_name": "40S ribosomal protein eS7 RPS7A", "refseq_ac": "NP_014739", "gene_names_uniprotkb": "RPS7A; RPS30; YOR3177W", "gene_names_refseq": "RPS30; RPS7A", "protein_names_uniprotkb": "Small ribosomal subunit protein eS7A; 40S ribosomal protein S7-A; RP30; RP40", "protein_names_refseq": "40S ribosomal protein eS7 RPS7A", "tax_id": 559292, "disease": "Diamond-Blackfan anemia 8 (Disease Ontology:DOID:0111881)", "pathway": " (sce:YOR096W); (R-SCE-156827); (R-SCE-1799339); (R-SCE-6791226); (R-SCE-72649); (R-SCE-72689); (R-SCE-72695); (R-SCE-72702); (R-SCE-72706); (R-SCE-975956); (R-SCE-975957); (R-SCE-9954714)", "pathway_count": 12, "publication_count": 22, "publication_id_list": "10601260;14562095;14562106;1544921;15590835;18407956;19684113;19795423;19823750;20702584;22096102;22106047;23749301;24374639;24524803;30609991;32597660;33481703;33491328;9169874;9200815;9559554", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (PubMed:22096102). eS7 is involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (PubMed:15590835)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2F7;Q08502", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0030686 90S preribosome;GO:0032040 small-subunit processome;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0042254 ribosome biogenesis;GO:0006364 rRNA processing;GO:0002181 cytoplasmic translation;GO:0042274 ribosomal small subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "P26786-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P26793-1", "uniprot_id": "FEN1_YEAST", "mass": 43279.0, "length": 382, "protein_name": "Flap endonuclease 1", "gene_name": "RAD27", "organism": "Yeast", "refseq_name": "multifunctional nuclease RAD27", "refseq_ac": "NP_012809", "gene_names_uniprotkb": "RAD27; FEN1; RTH1; YKL510", "gene_names_refseq": "ERC11; FEN1; RAD27; RTH1", "protein_names_uniprotkb": "Flap endonuclease 1; 3.1.-.-; FEN-1; Flap structure-specific endonuclease 1; RAD2 homolog nuclease 1; RTH1 nuclease; Structure-specific endonuclease RAD27", "protein_names_refseq": "multifunctional nuclease RAD27", "tax_id": 559292, "disease": "breast cancer (Disease Ontology:DOID:1612); cancer (Disease Ontology:DOID:162)", "pathway": " (sce:YKL113C); (R-SCE-69166)", "pathway_count": 2, "publication_count": 20, "publication_id_list": "10899134;11825897;12424238;14562095;14562106;1561835;16837458;17138563;18443037;19075004;19699691;20190278;21126336;22814378;24374639;33491328;7814325;7926735;8196765;9166764", "class_list": "", "function": "Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA., [UniProtKB, HAMAP, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXH5", "ec_number_list": "2.7.7.-;2.7.7.7;3.1.11.-;3.1.-.-", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0003677 DNA binding;GO:0008409 5'-3' exonuclease activity;GO:0017108 5'-flap endonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0006284 base-excision repair;GO:0006303 double-strand break repair via nonhomologous end joining;GO:0043137 DNA replication, removal of RNA primer;GO:0007534 gene conversion at mating-type locus;GO:0035753 maintenance of DNA trinucleotide repeats", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P26793-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P27351-1", "uniprot_id": "AP2B_YEAST", "mass": 80453.0, "length": 700, "protein_name": "AP-2 complex subunit beta", "gene_name": "APL1", "organism": "Yeast", "refseq_name": "Apl1p", "refseq_ac": "NP_012538", "gene_names_uniprotkb": "APL1; J1422; YAP80", "gene_names_refseq": "APL1; YAP80", "protein_names_uniprotkb": "AP-2 complex subunit beta; Beta-2-adaptin; Beta-adaptin; Clathrin assembly protein complex 2 beta large chain; Clathrin assembly protein large beta chain", "protein_names_refseq": "Apl1p", "tax_id": 559292, "disease": "Kartagener syndrome (Disease Ontology:DOID:0050144); visceral heterotaxy (Disease Ontology:DOID:0050545); middle cerebral artery infarction (Disease Ontology:DOID:3525); primary ciliary dyskinesia (Disease Ontology:DOID:9562)", "pathway": " (sce:YJR005W); (R-SCE-437239); (R-SCE-8856825); (R-SCE-8856828); (R-SCE-8866427); (R-SCE-8964038)", "pathway_count": 6, "publication_count": 11, "publication_id_list": "10564262;14562106;17287358;18407956;19779198;2122239;24374639;32597660;33481703;33491328;8641269", "class_list": "", "function": "Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Beta adaptin is a subunit of the plasma membrane adaptor., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWH9", "ec_number_list": "", "go_molecular_function": "GO:0030276 clathrin binding", "go_cellular_component": "GO:0030139 endocytic vesicle;GO:0030122 AP-2 adaptor complex;GO:0005935 cellular bud neck", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006897 endocytosis;GO:0016192 vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P27351-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P27466-1", "uniprot_id": "KCC1_YEAST", "mass": 50296.0, "length": 446, "protein_name": "Calcium/calmodulin-dependent protein kinase I", "gene_name": "CMK1", "organism": "Yeast", "refseq_name": "calmodulin-dependent protein kinase CMK1", "refseq_ac": "NP_116669", "gene_names_uniprotkb": "CMK1", "gene_names_refseq": "CMK1", "protein_names_uniprotkb": "Calcium/calmodulin-dependent protein kinase I; 2.7.11.17", "protein_names_refseq": "calmodulin-dependent protein kinase CMK1", "tax_id": 559292, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); withdrawal disorder (Disease Ontology:DOID:0060001); alcohol use disorder (Disease Ontology:DOID:1574); cocaine dependence (Disease Ontology:DOID:9975)", "pathway": " (sce:YFR014C)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "14562106;17330950;18407956;19684113;19779198;19795423;19823750;2026147;20489023;2061341;20702584;21126336;21177495;23749301;24374639;30516470;32597660;33481703;33491328;7670463", "class_list": "", "function": "Important in cellular regulation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 17, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTP5", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0004683 calcium/calmodulin-dependent protein kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0007165 signal transduction;GO:0034599 cellular response to oxidative stress", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P27466-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P27472-1", "uniprot_id": "GYS2_YEAST", "mass": 80079.0, "length": 705, "protein_name": "Glycogen [starch] synthase isoform 2", "gene_name": "GSY2", "organism": "Yeast", "refseq_name": "glycogen (starch) synthase GSY2", "refseq_ac": "NP_013359", "gene_names_uniprotkb": "GSY2; L8479.8", "gene_names_refseq": "GSY2", "protein_names_uniprotkb": "Glycogen [starch] synthase isoform 2; 2.4.1.11", "protein_names_refseq": "glycogen (starch) synthase GSY2", "tax_id": 559292, "disease": "cardiovascular system disease (Disease Ontology:DOID:1287); glycogen storage disease (Disease Ontology:DOID:2747); Lafora disease (Disease Ontology:DOID:3534)", "pathway": " (sce:YLR258W); (R-SCE-3322077)", "pathway_count": 2, "publication_count": 30, "publication_id_list": "10490639;11875433;12372297;14562106;15665377;15680913;17330950;17563356;18407956;1908457;19684113;19779198;20489023;20702584;20876143;21126336;2114092;21177495;22218487;23749301;24374639;30516470;32597660;33481703;33491328;38832010;8226915;8754836;9169871;9584169", "class_list": "", "function": "Glycogen synthase participates in the glycogen biosynthetic process along with glycogenin and glycogen branching enzyme. Extends the primer composed of a few glucose units formed by glycogenin by adding new glucose units to it. In this context, glycogen synthase transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYQ5", "ec_number_list": "2.4.1.11;2.4.1.18;2.4.1.186", "go_molecular_function": "GO:0042802 identical protein binding;GO:0004373 alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity;GO:2001069 glycogen binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0042587 glycogen granule", "go_biological_process": "GO:0005978 glycogen biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 3.1, "record_id": "P27472-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P27476-1", "uniprot_id": "NSR1_YEAST", "mass": 44535.0, "length": 414, "protein_name": "Nuclear localization sequence-binding protein", "gene_name": "NSR1", "organism": "Yeast", "refseq_name": "Nsr1p", "refseq_ac": "NP_011675", "gene_names_uniprotkb": "NSR1; G7001", "gene_names_refseq": "NSR1; SHE5", "protein_names_uniprotkb": "Nuclear localization sequence-binding protein; p67", "protein_names_refseq": "Nsr1p", "tax_id": 559292, "disease": "silicosis (Disease Ontology:DOID:10325); transient cerebral ischemia (Disease Ontology:DOID:224); uremia (Disease Ontology:DOID:4676); pancreatic carcinoma (Disease Ontology:DOID:4905); hepatocellular carcinoma (Disease Ontology:DOID:684); rheumatoid arthritis (Disease Ontology:DOID:7148)", "pathway": " (sce:YGR159C)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "12756332;14562106;14690591;15604408;1644811;1706724;17873058;18407956;21126336;21177495;22218487;23222640;23749301;24374639;26046779;26081071;32597660;33481703;33491328;33856219;7800479;8585325;9169869", "class_list": "", "function": "Involved in pre-rRNA processing (PubMed:1644811). Specifically binds nuclear localization sequences (PubMed:1706724). Candidate for a receptor at the nucleus that may be involved in both RNA and protein transport (Probable). Binds telomeric sequences of the type (TG[1-3])n in vitro (PubMed:7800479)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 25, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUT9", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0003729 mRNA binding;GO:0051880 G-quadruplex DNA binding;GO:0043047 single-stranded telomeric DNA binding;GO:0008139 nuclear localization sequence binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005730 nucleolus;GO:0005739 mitochondrion", "go_biological_process": "GO:0006310 DNA recombination;GO:0006364 rRNA processing;GO:0051276 chromosome organization;GO:0000028 ribosomal small subunit assembly", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P27476-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P27514-1", "uniprot_id": "PHO91_YEAST", "mass": 99490.0, "length": 894, "protein_name": "Low-affinity phosphate transporter PHO91", "gene_name": "PHO91", "organism": "Yeast", "refseq_name": "Pho91p", "refseq_ac": "NP_014410", "gene_names_uniprotkb": "PHO91; N2052", "gene_names_refseq": "PHO91", "protein_names_uniprotkb": "Low-affinity phosphate transporter PHO91", "protein_names_refseq": "Pho91p", "tax_id": 559292, "disease": "alcohol-related neurodevelopmental disorder (Disease Ontology:DOID:0050667); developmental and epileptic encephalopathy 25 (Disease Ontology:DOID:0080453); Kohlschutter-Tonz syndrome (Disease Ontology:DOID:0111668); epilepsy (Disease Ontology:DOID:1826)", "pathway": " (sce:YNR013C)", "pathway_count": 1, "publication_count": 25, "publication_id_list": "11779791;12821119;14562106;17330950;17563356;17804816;18165238;18407956;19779198;20133652;20702584;21126336;21177495;2169608;22218487;23749301;24374639;24909858;30516470;32597660;33229814;33481703;33491328;7900425;9169873", "class_list": "", "function": "Vacuolar phosphate transporter that probably exports phosphate from the vacuolar lumen to the cytosol., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 4, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 4, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 4, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 4, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6W1I8", "ec_number_list": "", "go_molecular_function": "GO:0015169 glycerol-3-phosphate transmembrane transporter activity;GO:0005315 phosphate transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0000329 fungal-type vacuole membrane;GO:1990816 vacuole-mitochondrion membrane contact site", "go_biological_process": "GO:0015794 glycerol-3-phosphate transmembrane transport;GO:0055085 transmembrane transport;GO:0006817 phosphate ion transport;GO:0006797 polyphosphate metabolic process;GO:2000185 regulation of phosphate transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 3.1, "record_id": "P27514-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P27515-1", "uniprot_id": "URK1_YEAST", "mass": 56296.0, "length": 501, "protein_name": "Uridine kinase", "gene_name": "URK1", "organism": "Yeast", "refseq_name": "uridine kinase URK1", "refseq_ac": "NP_014409", "gene_names_uniprotkb": "URK1; N2050", "gene_names_refseq": "URK1", "protein_names_uniprotkb": "Uridine kinase; 2.7.1.48; Uridine monophosphokinase", "protein_names_refseq": "uridine kinase URK1", "tax_id": 559292, "disease": "", "pathway": " (sce:YNR012W); (R-SCE-73614)", "pathway_count": 2, "publication_count": 19, "publication_id_list": "10501935;14562095;15665377;17330950;17563356;18407956;19779198;20702584;21126336;2169608;23749301;24374639;30516470;32597660;33229814;33481703;33491328;7900425;9169873", "class_list": "", "function": "Catalyzes the conversion of uridine into UMP and cytidine into CMP in the pyrimidine salvage pathway., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6W1I7", "ec_number_list": "2.7.1.48", "go_molecular_function": "GO:0005524 ATP binding;GO:0004849 uridine kinase activity;GO:0043771 cytidine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0008655 pyrimidine-containing compound salvage;GO:0044206 UMP salvage;GO:0044211 CTP salvage", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P27515-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P27614-1", "uniprot_id": "CBPS_YEAST", "mass": 64597.0, "length": 576, "protein_name": "Carboxypeptidase S", "gene_name": "CPS1", "organism": "Yeast", "refseq_name": "Gly-Xaa carboxypeptidase", "refseq_ac": "NP_012363", "gene_names_uniprotkb": "CPS1; CPS; J0510", "gene_names_refseq": "CPS1", "protein_names_uniprotkb": "Carboxypeptidase S; 3.4.17.4; GLY-X carboxypeptidase; YSCS", "protein_names_refseq": "Gly-Xaa carboxypeptidase", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL172W); (R-SCE-9673163)", "pathway_count": 2, "publication_count": 14, "publication_id_list": "11566881;11788821;14562106;1569061;1709881;2026161;22106047;22814378;24374639;32597660;33481703;33491328;8188249;8641269", "class_list": "", "function": "Vacuolar peptidase that is necessary for use of certain peptides as sole nitrogen source (PubMed:2026161). May also cleave intracellularly generated peptides to recycle amino acids for protein synthesis (PubMed:2026161)., [UniProtKB, PubMed]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6VW16", "ec_number_list": "3.4.17.4", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004180 carboxypeptidase activity;GO:0004181 metallocarboxypeptidase activity", "go_cellular_component": "GO:0005774 vacuolar membrane;GO:0005775 vacuolar lumen;GO:0000324 fungal-type vacuole;GO:0000328 fungal-type vacuole lumen", "go_biological_process": "GO:0051603 proteolysis involved in protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P27614-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P27636-1", "uniprot_id": "CDC15_YEAST", "mass": 110242.0, "length": 974, "protein_name": "Cell division control protein 15", "gene_name": "CDC15", "organism": "Yeast", "refseq_name": "serine/threonine protein kinase CDC15", "refseq_ac": "NP_009411", "gene_names_uniprotkb": "CDC15; LYT1", "gene_names_refseq": "CDC15; LYT1; RLT1", "protein_names_uniprotkb": "Cell division control protein 15; 2.7.11.1", "protein_names_refseq": "serine/threonine protein kinase CDC15", "tax_id": 559292, "disease": "diffuse gastric cancer (Disease Ontology:DOID:0080763); 46,XY sex reversal 6 (Disease Ontology:DOID:0111769); stomach cancer (Disease Ontology:DOID:10534); breast cancer (Disease Ontology:DOID:1612); rectum cancer (Disease Ontology:DOID:1993); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung non-small cell carcinoma (Disease Ontology:DOID:3908); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (sce:YAR019C); (R-SCE-2871796)", "pathway_count": 2, "publication_count": 50, "publication_id_list": "10413604;10662594;10744974;10837230;11267871;11290702;11378390;11404483;11598184;12832486;12937277;14562095;14562106;14718561;1495480;15665377;1658741;17330950;17563356;17660551;18407956;1882551;19779198;19795423;19823750;20046099;20123997;20442249;20505077;20702584;21126336;21937712;21987786;22031224;22218487;22385961;22718910;23749301;24013422;24039885;24374639;32597660;33481703;33491328;7731988;7941740;8175878;8407833;8491189;8668128", "class_list": "", "function": "Protein kinase of the mitotic exit network (MEN) essential for late nuclear division in the mitotic cycle. Promotes mitotic exit by phosphorylating DBF2 and directly switching on DBF2 kinase activity. Involved in the localization of DBF2 and DBF20 to the neck which is necessary to undergo cytokinesis. Plays a role in segregation of chromosomes during recovery from spindle checkpoint activation. Required for spindle pole localization of CDK1 and inactivation of CDC2 kinase activity at the end of mitosis. Required for spindle disassembly after meiosis II and plays a role in spore morphogenesis., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 30, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VPM6", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0000922 spindle pole;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005816 spindle pole body;GO:0005935 cellular bud neck", "go_biological_process": "GO:1904750 negative regulation of protein localization to nucleolus;GO:0000165 MAPK cascade;GO:0000281 mitotic cytokinesis;GO:0007096 regulation of exit from mitosis;GO:0051229 meiotic spindle disassembly", "synthesized_glycan_count": 0, "hit_score": 5.1, "record_id": "P27636-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P27637-1", "uniprot_id": "BUD14_YEAST", "mass": 78981.0, "length": 709, "protein_name": "Bud site selection protein 14", "gene_name": "BUD14", "organism": "Yeast", "refseq_name": "protein phosphatase regulator BUD14", "refseq_ac": "NP_009408", "gene_names_uniprotkb": "BUD14; FUN2", "gene_names_refseq": "BUD14", "protein_names_uniprotkb": "Bud site selection protein 14", "protein_names_refseq": "protein phosphatase regulator BUD14", "tax_id": 559292, "disease": "", "pathway": " (sce:YAR014C)", "pathway_count": 1, "publication_count": 28, "publication_id_list": "11452010;12477789;14562106;16107882;1658741;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20489023;20702584;21126336;21177495;21725298;22218487;22814378;23749301;24374639;24909858;30516470;32597660;33481703;33491328;7731988;7941740", "class_list": "", "function": "Important for bud site selection. Seems to be a regulatory subunit of the BUD14-GLC7 type-I phosphatase complex. The BUD14-GLC7 complex is necessary to regulate microtubule dynamics at the cortex and may function as a specific activator of the dynein complex., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 50, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VPM3", "ec_number_list": "", "go_molecular_function": "GO:0019888 protein phosphatase regulator activity", "go_cellular_component": "GO:0051286 cell tip;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0015630 microtubule cytoskeleton;GO:0000131 incipient cellular bud site", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0007010 cytoskeleton organization;GO:0032880 regulation of protein localization;GO:0060627 regulation of vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 2.9, "record_id": "P27637-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P27654-1", "uniprot_id": "TIP1_YEAST", "mass": 20728.0, "length": 210, "protein_name": "Temperature shock-inducible protein 1", "gene_name": "TIP1", "organism": "Yeast", "refseq_name": "putative lipase", "refseq_ac": "NP_009623", "gene_names_uniprotkb": "TIP1; YBR0622", "gene_names_refseq": "TIP1", "protein_names_uniprotkb": "Temperature shock-inducible protein 1; 3.1.1.-", "protein_names_refseq": "putative lipase", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR067C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10216230;11292809;14562106;15781460;16672383;1894636;24374639;7746155;7768807;7813418;9818717", "class_list": "", "function": "Seems to have esterase activity. Prefers ester of fatty acids from 4 to 16 carbon atoms., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VQ66", "ec_number_list": "", "go_molecular_function": "GO:0016298 lipase activity;GO:0005199 structural constituent of cell wall", "go_cellular_component": "GO:0005829 cytosol;GO:0071944 cell periphery;GO:0009277 fungal-type cell wall;GO:0098552 side of membrane", "go_biological_process": "GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P27654-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P27680-1", "uniprot_id": "COQ3_YEAST", "mass": 36331.0, "length": 312, "protein_name": "Ubiquinone biosynthesis O-methyltransferase, mitochondrial", "gene_name": "COQ3", "organism": "Yeast", "refseq_name": "hexaprenyldihydroxybenzoate methyltransferase", "refseq_ac": "NP_014545", "gene_names_uniprotkb": "COQ3; HRF316", "gene_names_refseq": "COQ3", "protein_names_uniprotkb": "Ubiquinone biosynthesis O-methyltransferase, mitochondrial; 2.1.1.-; 2.1.1.114; 2.1.1.64; 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; 3-demethylubiquinol 3-O-methyltransferase; 3-demethylubiquinone 3-O-methyltransferase; 3-demethylubiquinone-6 3-O-methyltransferase; DHHB methyltransferase; DHHB-MTase; DHHB-MT; Hexaprenyldihydroxybenzoate methyltransferase; Polyprenyldihydroxybenzoate methyltransferase", "protein_names_refseq": "hexaprenyldihydroxybenzoate methyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL096C); (R-SCE-2142789)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10419476;12748633;14562095;14562106;14576278;15792955;1885593;24374639;24406904;7502582;9169874", "class_list": "", "function": "O-methyltransferase required for two non-consecutive steps during ubiquinone biosynthesis (By similarity) (PubMed:10419476). Catalyzes the 2 O-methylation of 3,4-dihydroxy-5-(all-trans-hexaprenyl)benzoic acid into 4-hydroxy-3-methoxy-5-(all-trans-hexaprenyl)benzoic acid (By similarity) (PubMed:10419476). Also catalyzes the last step of ubiquinone biosynthesis by mediating methylation of 3-demethylubiquinone into ubiquinone (By similarity). Also able to mediate the methylation of 3-demethylubiquinol-6 into ubiquinol-6 (PubMed:10419476)., [UniProtKB, HAMAP, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1X2", "ec_number_list": "4.1.1.130;2.1.1.-;2.1.1.114;2.1.1.64;2.7.-.-;1.14.99.60;1.14.13.253;2.1.1.201;3.5.-.-;1.14.15.45;1.14.15.46", "go_molecular_function": "GO:0046872 metal ion binding;GO:0010420 polyprenyldihydroxybenzoate methyltransferase activity;GO:0061542 3-demethylubiquinol 3-O-methyltransferase activity;GO:0120537 3-demethylubiquinone 3-O-methyltransferase activity", "go_cellular_component": "GO:0031314 extrinsic component of mitochondrial inner membrane;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006744 ubiquinone biosynthetic process;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P27680-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P27697-1", "uniprot_id": "COQ8_YEAST", "mass": 56742.0, "length": 501, "protein_name": "Atypical kinase COQ8, mitochondrial", "gene_name": "COQ8", "organism": "Yeast", "refseq_name": "protein kinase COQ8", "refseq_ac": "NP_011396", "gene_names_uniprotkb": "COQ8; ABC1", "gene_names_refseq": "ABC1; COQ8", "protein_names_uniprotkb": "Atypical kinase COQ8, mitochondrial; 2.7.-.-; Activity of bc1 complex protein 1; Coenzyme Q protein 8; Ubiquinone biosynthesis protein COQ8", "protein_names_refseq": "protein kinase COQ8", "tax_id": 559292, "disease": "coenzyme Q10 deficiency disease (Disease Ontology:DOID:0050730); primary coenzyme Q10 deficiency 4 (Disease Ontology:DOID:0070241); nephrotic syndrome type 9 (Disease Ontology:DOID:0080391); nephrotic syndrome (Disease Ontology:DOID:1184)", "pathway": " (sce:YGL119W); (R-SCE-2142789)", "pathway_count": 2, "publication_count": 16, "publication_id_list": "10760477;11279158;14562106;15063807;1648478;18801050;19002377;20489023;21296186;24374639;25498144;27499294;33491328;9169869;9210471;9266513", "class_list": "", "function": "Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:27499294). Its substrate specificity is still unclear: may act as a protein kinase that mediates phosphorylation of COQ3, COQ5 and/or COQ7 (PubMed:11279158, PubMed:15063807, PubMed:1648478, PubMed:18801050, PubMed:19002377, PubMed:21296186, PubMed:25498144, PubMed:9210471, PubMed:9266513). According to other reports, acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway, as suggested by its ability to bind coenzyme Q lipid intermediates (By similarity)., [UniProtKB, UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 21, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VU29", "ec_number_list": "4.1.1.130;2.1.1.-;2.1.1.114;2.1.1.64;2.7.-.-;1.14.99.60;1.14.13.253;2.1.1.201;3.5.-.-;1.14.15.45;1.14.15.46", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0008289 lipid binding;GO:0016301 kinase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0016310 phosphorylation;GO:0006744 ubiquinone biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P27697-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P27796-1", "uniprot_id": "THIK_YEAST", "mass": 44730.0, "length": 417, "protein_name": "3-ketoacyl-CoA thiolase, peroxisomal", "gene_name": "POT1", "organism": "Yeast", "refseq_name": "acetyl-CoA C-acyltransferase", "refseq_ac": "NP_012106", "gene_names_uniprotkb": "POT1; FOX3; POX3", "gene_names_refseq": "FOX3; POT1; POX3", "protein_names_uniprotkb": "3-ketoacyl-CoA thiolase, peroxisomal; 2.3.1.16; Acetyl-CoA acyltransferase; Beta-ketothiolase; Peroxisomal 3-oxoacyl-CoA thiolase", "protein_names_refseq": "acetyl-CoA C-acyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL160C); (R-SCE-2046106); (R-SCE-390247); (R-SCE-6798695); (R-SCE-9033241)", "pathway_count": 5, "publication_count": 11, "publication_id_list": "1715273;17322287;1872029;22984289;23812376;24374639;7754706;7812714;8125978;9169870;9402066", "class_list": "", "function": "Responsible for the thiolytic cleavage of straight chain 3-keto fatty acyl-CoAs (3-oxoacyl-CoAs)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVC6", "ec_number_list": "3.5.3.1;3.4.23.25;2.3.1.16;2.7.1.35;3.5.1.3;2.3.2.27;3.2.1.14", "go_molecular_function": "GO:0003729 mRNA binding;GO:0003988 acetyl-CoA C-acyltransferase activity", "go_cellular_component": "GO:0005758 mitochondrial intermembrane space;GO:0005777 peroxisome;GO:0005782 peroxisomal matrix", "go_biological_process": "GO:0010124 phenylacetate catabolic process;GO:0006635 fatty acid beta-oxidation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P27796-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P27809-1", "uniprot_id": "KRE2_YEAST", "mass": 51387.0, "length": 442, "protein_name": "Glycolipid 2-alpha-mannosyltransferase", "gene_name": "KRE2", "organism": "Yeast", "refseq_name": "alpha-1,2-mannosyltransferase KRE2", "refseq_ac": "NP_010771", "gene_names_uniprotkb": "KRE2; D8035.26; MNT1", "gene_names_refseq": "KRE2; MNT1", "protein_names_uniprotkb": "Glycolipid 2-alpha-mannosyltransferase; 2.4.1.-; Alpha-1,2-mannosyltransferase", "protein_names_refseq": "alpha-1,2-mannosyltransferase KRE2", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR483W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562106;1541391;1550992;24374639;33481703;7754710;9169867", "class_list": "", "function": "Mannosyltransferase that transfers an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage. Required for the attachment of the third mannose residue of O-linked saccharides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VTA6", "ec_number_list": "", "go_molecular_function": "GO:0000026 alpha-1,2-mannosyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0005797 Golgi medial cisterna;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0000032 cell wall mannoprotein biosynthetic process;GO:0006493 protein O-linked glycosylation;GO:0006487 protein N-linked glycosylation;GO:0006491 N-glycan processing", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P27809-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P27810-1", "uniprot_id": "KTR1_YEAST", "mass": 46022.0, "length": 393, "protein_name": "Alpha-1,2 mannosyltransferase KTR1", "gene_name": "KTR1", "organism": "Yeast", "refseq_name": "alpha-1,2-mannosyltransferase KTR1", "refseq_ac": "NP_014742", "gene_names_uniprotkb": "KTR1; YOR3189W", "gene_names_refseq": "KTR1", "protein_names_uniprotkb": "Alpha-1,2 mannosyltransferase KTR1; 2.4.1.-", "protein_names_refseq": "alpha-1,2-mannosyltransferase KTR1", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR099W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14562106;1541391;19756047;24374639;9020857;9169874;9200815", "class_list": "", "function": "Mannosyltransferase that transfers a mannose residue from GDP-mannose to a range of acceptors in vitro, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W2G0", "ec_number_list": "", "go_molecular_function": "GO:0000026 alpha-1,2-mannosyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0000329 fungal-type vacuole membrane;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0000032 cell wall mannoprotein biosynthetic process;GO:0006493 protein O-linked glycosylation;GO:0006487 protein N-linked glycosylation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P27810-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P27825-1", "uniprot_id": "CALX_YEAST", "mass": 56968.0, "length": 502, "protein_name": "Calnexin homolog", "gene_name": "CNE1", "organism": "Yeast", "refseq_name": "calnexin", "refseq_ac": "NP_009343", "gene_names_uniprotkb": "CNE1; FUN48", "gene_names_refseq": "CNE1; FUN48", "protein_names_uniprotkb": "Calnexin homolog", "protein_names_refseq": "calnexin", "tax_id": 559292, "disease": "Parkinson's disease (Disease Ontology:DOID:14330); obesity (Disease Ontology:DOID:9970)", "pathway": " (sce:YAL058W); (R-SCE-901042)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "14562106;16002399;17322287;24374639;33491328;7731988;7814381;8465605", "class_list": "", "function": "Interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins., [UniProtKB, PubMed]", "predicted_glycosites": 6, "predicted_n_glycosites": 5, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "D6VPG1", "ec_number_list": "", "go_molecular_function": "GO:0051082 unfolded protein binding;GO:0005509 calcium ion binding;GO:0030246 carbohydrate binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006457 protein folding;GO:0036503 ERAD pathway", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P27825-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P27882-1", "uniprot_id": "ERV1_YEAST", "mass": 21639.0, "length": 189, "protein_name": "Mitochondrial FAD-linked sulfhydryl oxidase ERV1", "gene_name": "ERV1", "organism": "Yeast", "refseq_name": "flavin-linked sulfhydryl oxidase", "refseq_ac": "NP_011543", "gene_names_uniprotkb": "ERV1", "gene_names_refseq": "ERV1", "protein_names_uniprotkb": "Mitochondrial FAD-linked sulfhydryl oxidase ERV1; 1.8.3.2; 14 kDa regulatory protein; Essential for respiration and vegetative growth protein 1", "protein_names_refseq": "flavin-linked sulfhydryl oxidase", "tax_id": 559292, "disease": "renal fibrosis (Disease Ontology:DOID:0050855); autosomal recessive centronuclear myopathy (Disease Ontology:DOID:0111216); kidney failure (Disease Ontology:DOID:1074); cryptorchidism (Disease Ontology:DOID:11383); acute kidney failure (Disease Ontology:DOID:3021); ureteral obstruction (Disease Ontology:DOID:5199); autosomal dominant polycystic kidney disease (Disease Ontology:DOID:898)", "pathway": " (sce:YGR029W)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10899311;11493598;12654008;14576278;1552903;15989955;16181637;16185707;22814378;22984289;24374639;8226973;8972573;9169869;9290212", "class_list": "", "function": "FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation. Required for the import and folding of small cysteine-containing proteins in the mitochondrial intermembrane space (IMS). Forms a redox cycle with MIA40 that involves a disulfide relay system. Important for maintaining the cysteine residues in MIA40 in an oxidized state. Reduced ERV1 is reoxidized by cytochrome c. Required for the maturation of cytoplasmic, but not of mitochondrial Fe/S proteins., [UniProtKB, PubMed, PubMed, UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUG4", "ec_number_list": "1.8.3.2", "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding;GO:0016971 flavin-dependent sulfhydryl oxidase activity;GO:0016972 thiol oxidase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005758 mitochondrial intermembrane space", "go_biological_process": "GO:0045041 protein import into mitochondrial intermembrane space;GO:0006879 intracellular iron ion homeostasis;GO:0034599 cellular response to oxidative stress;GO:0160203 mitochondrial disulfide relay system", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P27882-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P27895-1", "uniprot_id": "CIN8_YEAST", "mass": 113311.0, "length": 1000, "protein_name": "Kinesin-like protein CIN8", "gene_name": "CIN8", "organism": "Yeast", "refseq_name": "kinesin motor protein CIN8", "refseq_ac": "NP_010853", "gene_names_uniprotkb": "CIN8; KSL2", "gene_names_refseq": "CIN8; KSL2; SDS15", "protein_names_uniprotkb": "Kinesin-like protein CIN8; Chromosome instability protein 8", "protein_names_refseq": "kinesin motor protein CIN8", "tax_id": 559292, "disease": "microcephaly with or without chorioretinopathy, lymphedema, or mental retardation (Disease Ontology:DOID:0060349); prostate cancer (Disease Ontology:DOID:10283); lung cancer (Disease Ontology:DOID:1324); breast cancer (Disease Ontology:DOID:1612); uterine cancer (Disease Ontology:DOID:363); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (sce:YEL061C); (R-SCE-983189)", "pathway_count": 2, "publication_count": 20, "publication_id_list": "12748633;14562095;14562106;14576278;1618897;1643659;18407956;19779198;20463882;21126336;22814378;23749301;24374639;25313961;28455557;32597660;33481703;33491328;7867803;9169868", "class_list": "", "function": "Elongates the mitotic spindle by interacting with spindle microtubules to generate an outward force pushing spindle poles apart (PubMed:1618897, PubMed:1643659, PubMed:25313961). Following spindle assembly, CIN8 and KIP1 apparently act to oppose a force, possibly generated by KAR3, that draws separated poles back together (PubMed:1618897, PubMed:1643659)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLI9", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0003777 microtubule motor activity;GO:0008569 minus-end-directed microtubule motor activity;GO:0008574 plus-end-directed microtubule motor activity", "go_cellular_component": "GO:0005828 kinetochore microtubule;GO:0000235 astral microtubule;GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0000776 kinetochore", "go_biological_process": "GO:0051301 cell division;GO:0090307 mitotic spindle assembly;GO:0007018 microtubule-based movement;GO:0007019 microtubule depolymerization;GO:0000070 mitotic sister chromatid segregation", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P27895-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P28495-1", "uniprot_id": "CAPZA_YEAST", "mass": 30699.0, "length": 268, "protein_name": "F-actin-capping protein subunit alpha", "gene_name": "CAP1", "organism": "Yeast", "refseq_name": "Cap1p", "refseq_ac": "NP_012918", "gene_names_uniprotkb": "CAP1; YKL155", "gene_names_refseq": "CAP1", "protein_names_uniprotkb": "F-actin-capping protein subunit alpha", "protein_names_refseq": "Cap1p", "tax_id": 559292, "disease": "intellectual disability (Disease Ontology:DOID:1059); male infertility (Disease Ontology:DOID:12336)", "pathway": " (sce:YKL007W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "1447293;14562106;17322287;18407956;21177495;22814378;24374639;33481703;33491328;38088874;8196765;8488728", "class_list": "", "function": "F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXS9", "ec_number_list": "", "go_molecular_function": "GO:0051015 actin filament binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0015629 actin cytoskeleton;GO:0008290 F-actin capping protein complex;GO:0030863 cortical cytoskeleton;GO:0030479 actin cortical patch", "go_biological_process": "GO:0030036 actin cytoskeleton organization;GO:0051016 barbed-end actin filament capping", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P28495-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P28791-1", "uniprot_id": "SEC20_YEAST", "mass": 43882.0, "length": 383, "protein_name": "Protein transport protein SEC20", "gene_name": "SEC20", "organism": "Yeast", "refseq_name": "Sec20p", "refseq_ac": "NP_010786", "gene_names_uniprotkb": "SEC20; D9719.4", "gene_names_refseq": "SEC20", "protein_names_uniprotkb": "Protein transport protein SEC20", "protein_names_refseq": "Sec20p", "tax_id": 559292, "disease": "Down syndrome (Disease Ontology:DOID:14250)", "pathway": " (sce:YDR498C); (R-SCE-6811434)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "12853481;14562106;1537327;17322287;19795423;19823750;24374639;9169867", "class_list": "", "function": "SNARE required for targeting and fusion of Golgi-derived retrograde transport vesicles with the ER., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTC0", "ec_number_list": "", "go_molecular_function": "GO:0005484 SNAP receptor activity", "go_cellular_component": "GO:0098554 cytoplasmic side of endoplasmic reticulum membrane;GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0031201 SNARE complex;GO:0012508 Golgi to ER transport vesicle membrane", "go_biological_process": "GO:0015031 protein transport;GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0007029 endoplasmic reticulum organization;GO:0048279 vesicle fusion with endoplasmic reticulum", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P28791-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P29055-1", "uniprot_id": "TF2B_YEAST", "mass": 38200.0, "length": 345, "protein_name": "Transcription initiation factor IIB", "gene_name": "SUA7", "organism": "Yeast", "refseq_name": "transcription factor SUA7", "refseq_ac": "NP_015411", "gene_names_uniprotkb": "SUA7; P9513.4", "gene_names_refseq": "SOH4; SUA7", "protein_names_uniprotkb": "Transcription initiation factor IIB; General transcription factor TFIIB; Transcription factor E", "protein_names_refseq": "transcription factor SUA7", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR086W); (R-SCE-674695); (R-SCE-6807505); (R-SCE-73776); (R-SCE-73779); (R-SCE-75953); (R-SCE-76042)", "pathway_count": 7, "publication_count": 6, "publication_id_list": "14562106;1547497;17322287;24374639;33491328;9169875", "class_list": "", "function": "General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W488;E9P939", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000993 RNA polymerase II complex binding;GO:0017025 TBP-class protein binding;GO:0016251 RNA polymerase II general transcription initiation factor activity;GO:0001139 RNA polymerase II complex recruiting activity", "go_cellular_component": "GO:0097550 transcription preinitiation complex;GO:0005634 nucleus", "go_biological_process": "GO:0006352 DNA-templated transcription initiation;GO:0001113 transcription open complex formation at RNA polymerase II promoter;GO:0051123 RNA polymerase II preinitiation complex assembly;GO:0001174 transcriptional start site selection at RNA polymerase II promoter", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P29055-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P29056-1", "uniprot_id": "TF3B_YEAST", "mass": 66906.0, "length": 596, "protein_name": "Transcription factor IIIB 70 kDa subunit", "gene_name": "BRF1", "organism": "Yeast", "refseq_name": "transcription factor TFIIIB subunit BRF1", "refseq_ac": "NP_011762", "gene_names_uniprotkb": "BRF1; PCF4; TDS4", "gene_names_refseq": "BRF1; PCF4; TDS4", "protein_names_uniprotkb": "Transcription factor IIIB 70 kDa subunit; B-related factor 1; BRF-1; TFIIIB", "protein_names_refseq": "transcription factor TFIIIB subunit BRF1", "tax_id": 559292, "disease": "fibroma (Disease Ontology:DOID:0050871); cerebellofaciodental syndrome (Disease Ontology:DOID:0080898); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (sce:YGR246C); (R-SCE-76061); (R-SCE-76066)", "pathway_count": 3, "publication_count": 16, "publication_id_list": "1398071;1423589;1423590;14562106;17287358;18407956;19779198;19795423;19823750;23749301;24374639;32597660;33481703;33491328;9133742;9169869", "class_list": "", "function": "General activator of RNA polymerase III transcription. Interacts with TBP. Binds to Pol III subunit C34 and to the TAU135 component of TFIIIC., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VV26", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0017025 TBP-class protein binding;GO:0001156 TFIIIC-class transcription factor complex binding;GO:0000994 RNA polymerase III core binding", "go_cellular_component": "GO:0097550 transcription preinitiation complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0000126 transcription factor TFIIIB complex", "go_biological_process": "GO:0006383 transcription by RNA polymerase III;GO:0006352 DNA-templated transcription initiation;GO:0070898 RNA polymerase III preinitiation complex assembly;GO:0006359 regulation of transcription by RNA polymerase III;GO:0001112 DNA-templated transcription open complex formation", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P29056-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P29295-1", "uniprot_id": "HRR25_YEAST", "mass": 57340.0, "length": 494, "protein_name": "Casein kinase I homolog HRR25", "gene_name": "HRR25", "organism": "Yeast", "refseq_name": "serine/threonine protein kinase HRR25", "refseq_ac": "NP_015120", "gene_names_uniprotkb": "HRR25", "gene_names_refseq": "HRR25; KTI14", "protein_names_uniprotkb": "Casein kinase I homolog HRR25; 2.7.11.1", "protein_names_refseq": "serine/threonine protein kinase HRR25", "tax_id": 559292, "disease": "familial adenomatous polyposis (Disease Ontology:DOID:0050424); advanced sleep phase syndrome (Disease Ontology:DOID:0050628); syndromic X-linked intellectual disability Najm type (Disease Ontology:DOID:0060807); advanced sleep phase syndrome 2 (Disease Ontology:DOID:0110012); Alzheimer's disease (Disease Ontology:DOID:10652); attention deficit hyperactivity disorder (Disease Ontology:DOID:1094); neurodegenerative disease (Disease Ontology:DOID:1289); cancer (Disease Ontology:DOID:162); colon cancer (Disease Ontology:DOID:219); invasive ductal carcinoma (Disease Ontology:DOID:3008); inclusion body myositis (Disease Ontology:DOID:3429); brain disease (Disease Ontology:DOID:936)", "pathway": " (sce:YPL204W); (R-SCE-6791226); (R-SCE-69601)", "pathway_count": 3, "publication_count": 21, "publication_id_list": "12628929;14562106;1495994;17330950;17563356;18407956;1887218;19779198;19795423;19823750;20489023;20702584;21460040;23749301;24374639;25569479;32597660;33229814;33481703;33491328;9169875", "class_list": "", "function": "Protein kinase which phosphorylates serine and threonine residues (PubMed:1495994). Can use casein as a substrate (PubMed:1495994). Phosphorylates elongator complex member ELP1/IKI3 on 'Ser-1198' and 'Ser-1202' which promotes the tRNA modification function of the complex (PubMed:25569479). Associated with repair of damaged DNA and meiosis (PubMed:1887218)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 7, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 7, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 7, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 12, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "D6W3G5", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;3.1.3.48;2.7.11.13;2.1.1.309;3.1.26.-;2.7.11.21;2.7.1.67;3.1.26.5;3.6.-.-;3.1.-.-;3.6.1.-", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0051455 spindle attachment to meiosis I kinetochore;GO:0060628 regulation of ER to Golgi vesicle-mediated transport;GO:0006281 DNA repair;GO:0006897 endocytosis;GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 3.0, "record_id": "P29295-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P29467-1", "uniprot_id": "MEI4_YEAST", "mass": 48215.0, "length": 408, "protein_name": "Meiosis-specific protein MEI4", "gene_name": "MEI4", "organism": "Yeast", "refseq_name": "Mei4p", "refseq_ac": "NP_010963", "gene_names_uniprotkb": "MEI4; YER044BC", "gene_names_refseq": "MEI4", "protein_names_uniprotkb": "Meiosis-specific protein MEI4", "protein_names_refseq": "Mei4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YER044C-A)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14992724;1545815;16783010;24374639;33491328;9169868", "class_list": "", "function": "Required for meiotic induction of recombination, viable spore production and chromosome synapsis. Component of the MER2-MEI4-REC114 complex which seems to be required for meiotic double-strand break (DSB) formation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLU5;P87265", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0005634 nucleus", "go_biological_process": "GO:0006310 DNA recombination;GO:0042138 meiotic DNA double-strand break formation;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P29467-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P29496-1", "uniprot_id": "MCM5_YEAST", "mass": 86411.0, "length": 775, "protein_name": "Minichromosome maintenance protein 5", "gene_name": "MCM5", "organism": "Yeast", "refseq_name": "MCM DNA helicase complex subunit MCM5", "refseq_ac": "NP_013376", "gene_names_uniprotkb": "MCM5; CDC46; L9328.1", "gene_names_refseq": "BOB1; CDC46; MCM5", "protein_names_uniprotkb": "Minichromosome maintenance protein 5; 3.6.4.12; Cell division control protein 46", "protein_names_refseq": "MCM DNA helicase complex subunit MCM5", "tax_id": 559292, "disease": "Meier-Gorlin syndrome (Disease Ontology:DOID:0060306); Meier-Gorlin syndrome 8 (Disease Ontology:DOID:0080255); alcohol use disorder (Disease Ontology:DOID:1574)", "pathway": " (sce:YLR274W); (R-SCE-176187); (R-SCE-68867); (R-SCE-68962); (R-SCE-69052)", "pathway_count": 5, "publication_count": 14, "publication_id_list": "1438234;14562106;15023545;17563356;18657510;19779198;19896182;19910535;2044962;23749301;24374639;33481703;33491328;9169871", "class_list": "", "function": "Acts as a component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity; specifically the MCM2-MCM5 association is proposed to be reversible and to mediate a open ring conformation which may facilitate DNA loading. Once loaded onto DNA, double hexamers can slide on dsDNA in the absence of ATPase activity., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYS1", "ec_number_list": "2.7.11.22;2.7.11.1;3.6.4.13;5.6.2.3;3.6.4.10;2.7.7.-;3.6.-.-;5.6.2.4;2.7.7.7;3.6.4.-;5.6.1.4;3.1.11.-;3.6.4.12;3.6.4.6;5.6.2.5;3.6.1.-;2.3.2.27;3.1.-.-;3.4.24.-;3.6.5.-;2.7.4.3;7.2.2.-", "go_molecular_function": "GO:0003688 DNA replication origin binding;GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003678 DNA helicase activity", "go_cellular_component": "GO:0005656 nuclear pre-replicative complex;GO:0031261 DNA replication preinitiation complex;GO:0043596 nuclear replication fork;GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication;GO:0030174 regulation of DNA-templated DNA replication initiation;GO:0031509 subtelomeric heterochromatin formation;GO:0006260 DNA replication;GO:0006368 transcription elongation by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P29496-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P29703-1", "uniprot_id": "FNTA_YEAST", "mass": 37508.0, "length": 316, "protein_name": "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "gene_name": "RAM2", "organism": "Yeast", "refseq_name": "bifunctional protein farnesyltransferase/protein geranylgeranyltransferase", "refseq_ac": "NP_012906", "gene_names_uniprotkb": "RAM2", "gene_names_refseq": "RAM2", "protein_names_uniprotkb": "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; 2.5.1.58; 2.5.1.59; CAAX farnesyltransferase subunit alpha; FTase-alpha; GGTase-I-alpha; PFTase/PGGTase I alpha; Ras proteins prenyltransferase subunit alpha; Type I protein geranyl-geranyltransferase subunit alpha", "protein_names_refseq": "bifunctional protein farnesyltransferase/protein geranylgeranyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YKL019W); (R-SCE-9648002)", "pathway_count": 2, "publication_count": 16, "publication_id_list": "10491163;1400380;14562106;1763050;1860864;1918005;2124698;24374639;7639519;8196765;8203154;8424764;8494894;8527442;9109664;9174352", "class_list": "", "function": "Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. If X is Ser, Ala, Met, Cys, or Gln, then the protein is farnesylated, if X is Leu or Phe, then the protein is geranylgeranylated. The alpha subunit wraps partly around the beta subunit forming part of the active site. The beta subunit is responsible for isoprenoid and peptide-binding., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXR6", "ec_number_list": "2.5.1.59;2.5.1.60;2.5.1.58", "go_molecular_function": "GO:0004660 protein farnesyltransferase activity;GO:0004661 protein geranylgeranyltransferase activity;GO:0004662 CAAX-protein geranylgeranyltransferase activity", "go_cellular_component": "GO:0005953 CAAX-protein geranylgeranyltransferase complex;GO:0005965 protein farnesyltransferase complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0018343 protein farnesylation;GO:0051604 protein maturation;GO:0018344 protein geranylgeranylation;GO:0007323 peptide pheromone maturation", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P29703-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P30656-1", "uniprot_id": "PSB5_YEAST", "mass": 31637.0, "length": 287, "protein_name": "Proteasome subunit beta type-5", "gene_name": "PRE2", "organism": "Yeast", "refseq_name": "proteasome core particle subunit beta 5", "refseq_ac": "NP_015428", "gene_names_uniprotkb": "PRE2; DOA3; P8283.10; PRG1", "gene_names_refseq": "DOA3; PRE2; PRG1; SRR2", "protein_names_uniprotkb": "Proteasome subunit beta type-5; 3.4.25.1; Macropain subunit PRE2; Multicatalytic endopeptidase complex subunit PRE2; Proteasome component PRE2; Proteinase YSCE subunit PRE2", "protein_names_refseq": "proteasome core particle subunit beta 5", "tax_id": 559292, "disease": "proteasome-associated autoinflammatory syndrome 1 (Disease Ontology:DOID:0050553); neurodegenerative disease (Disease Ontology:DOID:1289)", "pathway": " (sce:YPR103W); (R-SCE-1236974); (R-SCE-1236978); (R-SCE-5668541); (R-SCE-5689880); (R-SCE-9907900); (R-SCE-9912633)", "pathway_count": 7, "publication_count": 21, "publication_id_list": "11062564;11081519;1452031;14562106;16531229;16608349;16793518;18407956;20227375;20486117;22927375;23749301;24374639;32597660;33481703;33491328;7781614;8164651;8383129;9087403;9169875", "class_list": "", "function": "The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity. This unit is responsible of the chymotrypsin-like activity of the proteasome and is one of the principal target of the proteasome inhibitor bortezomib., [UniProtKB]; This subunit is necessary for chymotryptic activity and degradation of ubiquitinated proteins., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W4A1", "ec_number_list": "3.4.25.1;3.4.19.12;2.7.11.1", "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0004298 threonine-type endopeptidase activity", "go_cellular_component": "GO:0019774 proteasome core complex, beta-subunit complex;GO:0005634 nucleus;GO:0005777 peroxisome;GO:0005829 cytosol", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0080129 proteasome core complex assembly;GO:0010499 proteasomal ubiquitin-independent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P30656-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P31384-1", "uniprot_id": "CCR4_YEAST", "mass": 94670.0, "length": 837, "protein_name": "CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4", "gene_name": "CCR4", "organism": "Yeast", "refseq_name": "CCR4-NOT core exoribonuclease subunit CCR4", "refseq_ac": "NP_009381", "gene_names_uniprotkb": "CCR4; FUN27", "gene_names_refseq": "CCR4; FUN27; NUT21", "protein_names_uniprotkb": "CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4; 3.1.13.4; Carbon catabolite repressor protein 4; Cytoplasmic deadenylase; Glucose-repressible alcohol dehydrogenase transcriptional effector", "protein_names_refseq": "CCR4-NOT core exoribonuclease subunit CCR4", "tax_id": 559292, "disease": "heart disease (Disease Ontology:DOID:114)", "pathway": " (sce:YAL021C)", "pathway_count": 1, "publication_count": 26, "publication_id_list": "10490603;11239395;11733989;11889047;11889048;14562106;1459446;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21177495;23749301;24374639;30516470;32597660;33481703;33491328;7731988;8144453;8458570;9463387", "class_list": "", "function": "Acts as a catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. CCR4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA. Discovered because of its role in the control of ADH2 gene expression. It is required for the expression of genes involved in non-fermentative growth and it mediates or is required for the action of the SPT6 and SPT10 genes., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VPJ7", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0046872 metal ion binding;GO:0000175 3'-5'-RNA exonuclease activity;GO:0004535 poly(A)-specific ribonuclease activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0000932 P-body;GO:0016593 Cdc73/Paf1 complex;GO:0030015 CCR4-NOT core complex", "go_biological_process": "GO:0000076 DNA replication checkpoint signaling;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006260 DNA replication;GO:0006368 transcription elongation by RNA polymerase II;GO:0007089 traversing start control point of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 2.7, "record_id": "P31384-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32333-1", "uniprot_id": "BTAF1_YEAST", "mass": 209977.0, "length": 1867, "protein_name": "TATA-binding protein-associated factor MOT1", "gene_name": "MOT1", "organism": "Yeast", "refseq_name": "DNA-binding ATPase", "refseq_ac": "NP_015243", "gene_names_uniprotkb": "MOT1; LPF4C", "gene_names_refseq": "BUR3; END10; LPF4; MOT1", "protein_names_uniprotkb": "TATA-binding protein-associated factor MOT1; 3.6.4.-; Modifier of transcription 1; TBP-associated factor MOT1", "protein_names_refseq": "DNA-binding ATPase", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL082C)", "pathway_count": 1, "publication_count": 21, "publication_id_list": "11880621;12805227;1312673;14562095;14562106;14576278;16387868;17287358;17330950;18407956;19779198;19795423;19823750;20702584;23749301;24374639;32597660;33481703;33491328;9169875;9234740", "class_list": "", "function": "Regulates transcription in association with TATA binding protein (TBP). Removes TBP from the TATA box via its C-terminal ATPase activity. Both transcription activation and repression require its ATPase activity., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 20, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3T5", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0017025 TBP-class protein binding;GO:0004386 helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0000228 nuclear chromosome", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription;GO:0006364 rRNA processing;GO:0045898 regulation of RNA polymerase II transcription preinitiation complex assembly;GO:0042790 nucleolar large rRNA transcription by RNA polymerase I", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P32333-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32354-1", "uniprot_id": "MCM10_YEAST", "mass": 65815.0, "length": 571, "protein_name": "Minichromosome maintenance protein 10", "gene_name": "MCM10", "organism": "Yeast", "refseq_name": "Mcm10p", "refseq_ac": "NP_012116", "gene_names_uniprotkb": "MCM10; DNA43", "gene_names_refseq": "DNA43; MCM10", "protein_names_uniprotkb": "Minichromosome maintenance protein 10; Protein DNA43", "protein_names_refseq": "Mcm10p", "tax_id": 559292, "disease": "immunodeficiency 80 (Disease Ontology:DOID:0061051)", "pathway": " (sce:YIL150C); (R-SCE-176187); (R-SCE-68962)", "pathway_count": 3, "publication_count": 27, "publication_id_list": "10783164;11168584;12844493;13680157;14562106;1514326;15201046;15494305;16085704;16328881;16675460;16782870;17287358;18407956;19684113;19779198;19795423;19823750;20702584;21177495;23749301;24374639;32597660;33481703;33491328;9154825;9169870", "class_list": "", "function": "Required for DNA synthesis. Required for entry into or completion of S phase. Involved in DNA replication and seems to participate in the activation of the pre-replication complex (pre-RC) and in transcription elongation. May play a role as a key coordinator in assembling the replication fork. Proposed to function at replication origins following the binding of the MCM2-7 complex prior to the recruitment of CDC45. Probably is required to stimulate phosphorylation of the MCM2-7 complex by the CDC7-DBF4 kinase complex. May recruit the DNA polymerase alpha:primase complex to replication origins and is required to maintain it on chromatin independently of CDC45. May also play a role in transcriptional silencing., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 10, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVD7", "ec_number_list": "", "go_molecular_function": "GO:0003688 DNA replication origin binding;GO:0008270 zinc ion binding;GO:0003690 double-stranded DNA binding;GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0043596 nuclear replication fork;GO:0005634 nucleus;GO:0005657 replication fork;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0006271 DNA strand elongation involved in DNA replication;GO:0031509 subtelomeric heterochromatin formation;GO:0006270 DNA replication initiation;GO:0000727 double-strand break repair via break-induced replication;GO:1902969 mitotic DNA replication", "synthesized_glycan_count": 0, "hit_score": 2.8, "record_id": "P32354-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32457-1", "uniprot_id": "CDC3_YEAST", "mass": 60054.0, "length": 520, "protein_name": "Cell division control protein 3", "gene_name": "CDC3", "organism": "Yeast", "refseq_name": "septin CDC3", "refseq_ac": "NP_013418", "gene_names_uniprotkb": "CDC3; L8543.7", "gene_names_refseq": "CDC3", "protein_names_uniprotkb": "Cell division control protein 3", "protein_names_refseq": "septin CDC3", "tax_id": 559292, "disease": "Lewy body dementia (Disease Ontology:DOID:12217); Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (sce:YLR314C); (R-SCE-111457)", "pathway_count": 2, "publication_count": 35, "publication_id_list": "10579719;11587849;12058072;12429908;12665577;15166219;15282341;15542864;15665377;17287358;17330950;17563356;18407956;18791237;19684113;19779198;19795423;19823750;20489023;20702584;21126336;21177495;22218487;22814378;23749301;24374639;24909858;30516470;32597660;33481703;33491328;33502312;8791410;9169871;9813094", "class_list": "", "function": "Septins are GTPases involved in cytokinesis that assemble early in the cell cycle as a patch at the incipient bud site and form a ring approximate 15 minutes before bud emergence, which transforms into an hour-glass shaped collar of cortical filaments that spans both sides of the mother-bud neck. This collar persists until just before cytokinesis, when it splits into two rings that occupy opposite sides of the neck. The septins at the bud neck serve as a structural scaffold that recruits different components involved in diverse processes at specific stages during the cell cycle. Many proteins bind asymmetrically to the septin collar. The septin assembly is regulated by protein kinases GIN4 and/or CLA4. May act by recruiting MYO1 and HOF1, a protein involved in septation, to the site of cleavage. Septins are also involved in cell morphogenesis, bud site selection, chitin deposition, cell cycle regulation, cell compartmentalization and spore wall formation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 31, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYV8;Q06161", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0010314 phosphatidylinositol-5-phosphate binding;GO:0003924 GTPase activity;GO:0005200 structural constituent of cytoskeleton;GO:0005525 GTP binding", "go_cellular_component": "GO:0005940 septin ring;GO:0015630 microtubule cytoskeleton;GO:0031105 septin complex;GO:0032160 septin filament array;GO:0032153 cell division site", "go_biological_process": "GO:0000920 septum digestion after cytokinesis;GO:0000281 mitotic cytokinesis;GO:0008104 intracellular protein localization;GO:0000921 septin ring assembly;GO:0061640 cytoskeleton-dependent cytokinesis", "synthesized_glycan_count": 0, "hit_score": 3.6, "record_id": "P32457-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32489-1", "uniprot_id": "MEI5_YEAST", "mass": 26461.0, "length": 222, "protein_name": "Meiosis protein 5", "gene_name": "MEI5", "organism": "Yeast", "refseq_name": "Mei5p", "refseq_ac": "NP_015204", "gene_names_uniprotkb": "MEI5; LPH6C", "gene_names_refseq": "LPH6; MEI5", "protein_names_uniprotkb": "Meiosis protein 5", "protein_names_refseq": "Mei5p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL121C)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15620352;24374639;9169875", "class_list": "", "function": "Involved in meiotic DNA-break repair. Required for the recruitment of DCM1 to meiosis recombination hot spots., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3P6;Q02946", "ec_number_list": "", "go_molecular_function": "GO:0030234 enzyme regulator activity", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0005634 nucleus;GO:0000228 nuclear chromosome", "go_biological_process": "GO:0000707 meiotic DNA recombinase assembly;GO:0007131 reciprocal meiotic recombination;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P32489-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32490-1", "uniprot_id": "MKK1_YEAST", "mass": 56720.0, "length": 508, "protein_name": "MAP kinase kinase MKK1/SSP32", "gene_name": "MKK1", "organism": "Yeast", "refseq_name": "mitogen-activated protein kinase kinase MKK1", "refseq_ac": "NP_014874", "gene_names_uniprotkb": "MKK1; O5095; SSP32", "gene_names_refseq": "MKK1; SSP32", "protein_names_uniprotkb": "MAP kinase kinase MKK1/SSP32; 2.7.12.2", "protein_names_refseq": "mitogen-activated protein kinase kinase MKK1", "tax_id": 559292, "disease": "RASopathy (Disease Ontology:DOID:0080690); prostate cancer (Disease Ontology:DOID:10283); cancer (Disease Ontology:DOID:162)", "pathway": " (sce:YOR231W); (R-SCE-168638); (R-SCE-2559580); (R-SCE-2871796); (R-SCE-450302); (R-SCE-6811555)", "pathway_count": 6, "publication_count": 15, "publication_id_list": "12361575;14562106;15905473;18407956;19779198;20489023;23749301;24374639;30516470;32597660;33481703;33491328;8386320;8972580;9169874", "class_list": "", "function": "Involved in a signal transduction pathway that play a role in yeast cell morphogenesis and cell growth. This pathway seems to start by SMP3; then involve the kinase PKC1 that may act on the BCK1 kinase that then phosphorylates MKK1 and MKK2 which themselves phosphorylate the MPK1 kinase., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 23, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2T5;Q2VQW6", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;2.7.1.68;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0004708 MAP kinase kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005934 cellular bud tip;GO:0005935 cellular bud neck;GO:0043332 mating projection tip", "go_biological_process": "GO:0007165 signal transduction;GO:0000425 pexophagy;GO:0000196 cell integrity MAPK cascade;GO:0060237 regulation of fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P32490-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32494-1", "uniprot_id": "NGG1_YEAST", "mass": 79282.0, "length": 702, "protein_name": "SAGA complex subunit NGG1", "gene_name": "NGG1", "organism": "Yeast", "refseq_name": "histone acetyltransferase NGG1", "refseq_ac": "NP_010461", "gene_names_uniprotkb": "NGG1; ADA3; SWI7; YD9395.09", "gene_names_refseq": "ADA3; NGG1; SWI7", "protein_names_uniprotkb": "SAGA complex subunit NGG1; Chromatin-remodeling complexes subunit NGG1; Transcriptional adapter 3", "protein_names_refseq": "histone acetyltransferase NGG1", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR176W)", "pathway_count": 1, "publication_count": 35, "publication_id_list": "10026213;10490601;10864329;12186975;12446794;14562106;15260971;15340070;15647753;17330950;17563356;18407956;19779198;19795423;19823750;20489023;20702584;21734642;22218487;23749301;24374639;25216679;28918903;32597660;33481703;33491328;33864814;7862114;8262068;8413201;9154821;9169867;9674426;9756893;9885573", "class_list": "", "function": "Component of the transcription coactivator SAGA complex. SAGA acts as a general cofactor required for essentially all RNA polymerase II transcription (PubMed:10864329, PubMed:25216679, PubMed:28918903). At the promoters, SAGA is required for transcription pre-initiation complex (PIC) recruitment. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (via core/TAF module) and promoter selectivity, interaction with transcription activators (via Tra1/SPT module), and chromatin modification through histone acetylation (via HAT module) and deubiquitination (via DUB module) (PubMed:21734642). SAGA preferentially acetylates histones H3 (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac) and H2B and deubiquitinates histone H2B (PubMed:10026213). SAGA interacts with DNA via upstream activating sequences (UASs) (PubMed:28918903). Also identified in a modified version of SAGA named SALSA or SLIK (PubMed:12186975, PubMed:12446794). The cleavage of SPT7 and the absence of the SPT8 subunit in SLIK neither drive any major conformational differences in its structure compared with SAGA, nor significantly affect HAT, DUB, or DNA-binding activities (PubMed:33864814). Component of the ADA histone acetyltransferase complex, which preferentially acetylates nucleosomal histones H3 (to form H3K14ac and H3K18ac) and H2B (PubMed:10026213). May be involved in response to DNA damage by genotoxic agents (PubMed:15340070)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSF8", "ec_number_list": "", "go_molecular_function": "GO:0003713 transcription coactivator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000124 SAGA complex;GO:0046695 SLIK (SAGA-like) complex;GO:0140671 ADA complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 3.6, "record_id": "P32494-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32523-1", "uniprot_id": "PRP19_YEAST", "mass": 56570.0, "length": 503, "protein_name": "Pre-mRNA-processing factor 19", "gene_name": "PRP19", "organism": "Yeast", "refseq_name": "E3 ubiquitin-protein ligase PRP19", "refseq_ac": "NP_013064", "gene_names_uniprotkb": "PRP19; PSO4", "gene_names_refseq": "PRP19; PSO4", "protein_names_uniprotkb": "Pre-mRNA-processing factor 19; 2.3.2.27; RING-type E3 ubiquitin transferase PRP19", "protein_names_refseq": "E3 ubiquitin-protein ligase PRP19", "tax_id": 559292, "disease": "syndromic intellectual disability (Disease Ontology:DOID:0050888)", "pathway": " (sce:YLL036C); (R-SCE-6782135); (R-SCE-6782210)", "pathway_count": 3, "publication_count": 21, "publication_id_list": "11884590;12627222;14562106;14690591;15601865;17563356;18407956;19779198;20190278;21177495;22814378;23749301;24374639;32597660;33481703;33491328;7680101;8194532;8441419;8918805;9169871", "class_list": "", "function": "Probable ubiquitin-protein ligase involved in pre-mRNA splicing. Acts as a central component of the NTC complex (or PRP19-associated complex) that associates to the spliceosome to mediate conformational rearrangement or to stabilize the structure of the spliceosome after U4 snRNA dissociation, which leads to spliceosome maturation. It is also probably involved in DNA repair., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXW9;Q07870", "ec_number_list": "2.7.7.6;2.7.11.23;5.6.2.3;3.1.-.-;2.7.7.7;3.1.11.-;2.3.2.27;3.6.4.-;3.4.19.12;5.2.1.8;5.6.2.4", "go_molecular_function": "GO:0042802 identical protein binding;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0071006 U2-type catalytic step 1 spliceosome", "go_biological_process": "GO:0000349 generation of catalytic spliceosome for first transesterification step;GO:0006281 DNA repair;GO:0000398 mRNA splicing, via spliceosome;GO:0070534 protein K63-linked ubiquitination", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P32523-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32526-1", "uniprot_id": "KAR9_YEAST", "mass": 74245.0, "length": 644, "protein_name": "Karyogamy protein KAR9", "gene_name": "KAR9", "organism": "Yeast", "refseq_name": "Kar9p", "refseq_ac": "NP_015054", "gene_names_uniprotkb": "KAR9", "gene_names_refseq": "KAR9", "protein_names_uniprotkb": "Karyogamy protein KAR9; Cortical protein KAR9", "protein_names_refseq": "Kar9p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL269W)", "pathway_count": 1, "publication_count": 21, "publication_id_list": "12600318;14562106;16236795;17251549;17322287;18407956;18832349;19779198;19795423;19823750;22031224;23749301;24374639;27682587;32597660;33481703;33491328;34088668;8395015;9169875;9442113", "class_list": "", "function": "Involved in karyogamy. Component of a cortical adaptor complex that orients cytoplasmic microtubules. It may be involved in anchoring cytoplasmic microtubules to the cell cortex., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 31, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3A1;Q08982", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005938 cell cortex;GO:0000776 kinetochore;GO:0005881 cytoplasmic microtubule", "go_biological_process": "GO:0051293 establishment of spindle localization;GO:0030473 nuclear migration along microtubule;GO:0000741 karyogamy;GO:0031578 mitotic spindle orientation checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P32526-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32561-1", "uniprot_id": "RPD3_YEAST", "mass": 48904.0, "length": 433, "protein_name": "Histone deacetylase RPD3", "gene_name": "RPD3", "organism": "Yeast", "refseq_name": "histone deacetylase RPD3", "refseq_ac": "NP_014069", "gene_names_uniprotkb": "RPD3; MOF6; N0305; REC3; SDI2; SDS6", "gene_names_refseq": "MOF6; REC3; RPD3; SDI2; SDS6", "protein_names_uniprotkb": "Histone deacetylase RPD3; 3.5.1.98; Transcriptional regulatory protein RPD3", "protein_names_refseq": "histone deacetylase RPD3", "tax_id": 559292, "disease": "fetal alcohol spectrum disorder (Disease Ontology:DOID:0050696); stroke (Disease Ontology:DOID:0051061); prostate carcinoma (Disease Ontology:DOID:10286); stomach cancer (Disease Ontology:DOID:10534); alcohol use disorder (Disease Ontology:DOID:1574); glaucoma (Disease Ontology:DOID:1686); anxiety disorder (Disease Ontology:DOID:2030); multiple sclerosis (Disease Ontology:DOID:2377); asthma (Disease Ontology:DOID:2841); endometriosis (Disease Ontology:DOID:289); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); temporal lobe epilepsy (Disease Ontology:DOID:3328); breast carcinoma (Disease Ontology:DOID:3459); pancreatic ductal carcinoma (Disease Ontology:DOID:3587); bronchitis (Disease Ontology:DOID:6132); pulmonary hypertension (Disease Ontology:DOID:6432); hepatocellular carcinoma (Disease Ontology:DOID:684); Peyronie's disease (Disease Ontology:DOID:8616); prostate carcinoma in situ (Disease Ontology:DOID:8634); cervix uteri carcinoma in situ (Disease Ontology:DOID:8991); colorectal cancer (Disease Ontology:DOID:9256); pulmonary emphysema (Disease Ontology:DOID:9675); type 1 diabetes mellitus (Disease Ontology:DOID:9744); alopecia areata (Disease Ontology:DOID:986); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (sce:YNL330C); (R-SCE-3214815); (R-SCE-4551638)", "pathway_count": 3, "publication_count": 47, "publication_id_list": "10079324;10359799;10388812;10899127;10931932;11069890;12089521;12110674;12192044;12234935;12672825;12808094;14562095;14562106;14711989;14737171;15141165;15143171;15456858;16079223;16286008;16314178;17322287;17330950;17563356;18407956;1944291;19779198;19795423;19823750;20702584;22218487;23749301;24374639;32597660;33481703;33491328;7645347;8533474;8873448;8962081;8978024;9169873;9234741;9512514;9572144;9710596", "class_list": "", "function": "Catalytic component of the RPD3 histone deacetylase (HDAC) complexes RPD3C(L) and RPD3C(S) responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation plays an important role in transcriptional regulation, cell cycle progression, DNA damage response, osmotic stress response and developmental events. Is involved in rDNA and telomere silencing and in double strand breaks repair. Required for both full transcription repression and activation of many genes including cell type-specific genes (STE6, TY2 and HO), cell differentiation-specific genes (SPO13), genes that respond to external signals (PHO5) and TRK2. The RPD3 complexes regulate also chromosomal replication timing., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 13, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 25, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0L7", "ec_number_list": "3.5.1.98;2.3.2.-", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0003714 transcription corepressor activity;GO:0004407 histone deacetylase activity;GO:0141221 histone deacetylase activity, hydrolytic mechanism", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0034399 nuclear periphery;GO:0000118 histone deacetylase complex;GO:0070822 Sin3-type complex", "go_biological_process": "GO:0030174 regulation of DNA-templated DNA replication initiation;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006979 response to oxidative stress;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 4.8, "record_id": "P32561-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32565-1", "uniprot_id": "RPN2_YEAST", "mass": 104232.0, "length": 945, "protein_name": "26S proteasome regulatory subunit RPN2", "gene_name": "RPN2", "organism": "Yeast", "refseq_name": "proteasome regulatory particle base subunit RPN2", "refseq_ac": "NP_012190", "gene_names_uniprotkb": "RPN2; SEN3", "gene_names_refseq": "RPN2; SEN3", "protein_names_uniprotkb": "26S proteasome regulatory subunit RPN2", "protein_names_refseq": "proteasome regulatory particle base subunit RPN2", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL075C); (R-SCE-1236978); (R-SCE-5668541); (R-SCE-5689880); (R-SCE-6798695); (R-SCE-9907900)", "pathway_count": 6, "publication_count": 14, "publication_id_list": "10688918;12504901;14562106;18407956;20486117;21126336;22814378;22927375;24374639;33481703;33491328;7565784;9169870;9584156", "class_list": "", "function": "Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VVK9", "ec_number_list": "", "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding;GO:0030234 enzyme regulator activity", "go_cellular_component": "GO:0034515 proteasome storage granule;GO:0008540 proteasome regulatory particle, base subcomplex;GO:0005634 nucleus", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0043248 proteasome assembly;GO:0042176 regulation of protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P32565-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32591-1", "uniprot_id": "SWI3_YEAST", "mass": 92926.0, "length": 825, "protein_name": "SWI/SNF complex subunit SWI3", "gene_name": "SWI3", "organism": "Yeast", "refseq_name": "Swi3p", "refseq_ac": "NP_012359", "gene_names_uniprotkb": "SWI3; J0495; TYE2", "gene_names_refseq": "HAF2; SWI3; TYE2", "protein_names_uniprotkb": "SWI/SNF complex subunit SWI3; Transcription factor TYE2; Transcription regulatory protein SWI3", "protein_names_refseq": "Swi3p", "tax_id": 559292, "disease": "opportunistic bacterial infectious disease (Disease Ontology:DOID:0050340); colorectal carcinoma (Disease Ontology:DOID:0080199); Coffin-Siris syndrome 8 (Disease Ontology:DOID:0112367); hydrocephalus (Disease Ontology:DOID:10908); alcohol use disorder (Disease Ontology:DOID:1574); cancer (Disease Ontology:DOID:162); Coffin-Siris syndrome (Disease Ontology:DOID:1925); renal cell carcinoma (Disease Ontology:DOID:4450); hepatocellular carcinoma (Disease Ontology:DOID:684); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (sce:YJL176C)", "pathway_count": 1, "publication_count": 24, "publication_id_list": "12524530;1339306;14562106;15506919;16204215;16461455;17563356;18407956;19779198;19795423;19823750;20190278;21126336;21177495;23749301;24374639;30516470;32597660;33229814;33481703;33491328;33502312;8221926;8641269", "class_list": "", "function": "Involved in transcriptional activation. Component of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 10, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 10, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 10, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 28, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 10, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "D6VW13", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0016514 SWI/SNF complex;GO:0000785 chromatin", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 3.6, "record_id": "P32591-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32598-1", "uniprot_id": "PP12_YEAST", "mass": 35907.0, "length": 312, "protein_name": "Serine/threonine-protein phosphatase PP1-2", "gene_name": "GLC7", "organism": "Yeast", "refseq_name": "type 1 serine/threonine-protein phosphatase catalytic subunit GLC7", "refseq_ac": "NP_011059", "gene_names_uniprotkb": "GLC7; CID1; DIS2", "gene_names_refseq": "CID1; DIS2; GLC7", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase PP1-2; 3.1.3.16", "protein_names_refseq": "type 1 serine/threonine-protein phosphatase catalytic subunit GLC7", "tax_id": 559292, "disease": "Noonan syndrome-like disorder with loose anagen hair 2 (Disease Ontology:DOID:0080693); cancer (Disease Ontology:DOID:162); congestive heart failure (Disease Ontology:DOID:6000); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (sce:YER133W); (R-SCE-2500257)", "pathway_count": 2, "publication_count": 22, "publication_id_list": "10975519;12356757;12477789;12819204;14562106;14690591;16107882;1660885;18407956;19795423;19823750;20190278;20489023;22106047;22521787;22814378;24374639;2544298;33481703;33491328;8150278;9169868", "class_list": "", "function": "Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. Component of the APT complex, which may be involved in polyadenylation-independent transcript 3'-end formation., [UniProtKB]; Involved in control of glycogen metabolism, meiosis, translation, chromosome segregation, cell polarity and G2/M cell cycle progression. PP1 may act in opposition to the IPL1 protein kinase in regulating chromosome segregation by dephosphorylating H3S10ph. The BUD14-GLC7 complex is necessary to regulate microtubule dynamics at the cortex and may function as a specific activator of the dynein complex (PubMed:10975519, PubMed:16107882). May dephosphorylate the outer kinetochore protein SPC105 to oppose the action of kinase MPS1 in spindle assembly checkpoint (SAC) signaling (PubMed:22521787)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DM39", "ec_number_list": "3.1.3.16;3.1.3.43;2.7.11.21;3.1.3.48", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0000164 protein phosphatase type 1 complex;GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0000776 kinetochore", "go_biological_process": "GO:0000076 DNA replication checkpoint signaling;GO:0006397 mRNA processing;GO:0007059 chromosome segregation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0005977 glycogen metabolic process", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "P32598-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32600-1", "uniprot_id": "TOR2_YEAST", "mass": 281568.0, "length": 2474, "protein_name": "Serine/threonine-protein kinase TOR2", "gene_name": "TOR2", "organism": "Yeast", "refseq_name": "phosphatidylinositol kinase-related protein kinase TOR2", "refseq_ac": "NP_012719", "gene_names_uniprotkb": "TOR2; DRR2; TSC14", "gene_names_refseq": "DRR2; TOR2", "protein_names_uniprotkb": "Serine/threonine-protein kinase TOR2; 2.7.1.67; 2.7.11.1; Dominant rapamycin resistance protein 2; PI4-kinase TOR2; PI4K TOR2; Phosphatidylinositol 4-kinase TOR2; PtdIns-4-kinase TOR2; Target of rapamycin kinase 2; Temperature-sensitive CSG2 suppressor protein 14", "protein_names_refseq": "phosphatidylinositol kinase-related protein kinase TOR2", "tax_id": 559292, "disease": "alcohol-associated liver disease (Disease Ontology:DOID:0070658); polycystic kidney disease (Disease Ontology:DOID:0080322); autosomal recessive polycystic kidney disease (Disease Ontology:DOID:0110861); prostate cancer (Disease Ontology:DOID:10283); portal hypertension (Disease Ontology:DOID:10762); hypertension (Disease Ontology:DOID:10763); sciatic neuropathy (Disease Ontology:DOID:11446); crescentic glomerulonephritis (Disease Ontology:DOID:13139); interstitial cystitis (Disease Ontology:DOID:13949); pancreatic cancer (Disease Ontology:DOID:1793); status epilepticus (Disease Ontology:DOID:1824); colon cancer (Disease Ontology:DOID:219); transient cerebral ischemia (Disease Ontology:DOID:224); idiopathic interstitial pneumonia (Disease Ontology:DOID:2797); acute kidney failure (Disease Ontology:DOID:3021); high grade glioma (Disease Ontology:DOID:3070); temporal lobe epilepsy (Disease Ontology:DOID:3328); chondrosarcoma (Disease Ontology:DOID:3371); middle cerebral artery infarction (Disease Ontology:DOID:3525); renal cell carcinoma (Disease Ontology:DOID:4450); ureteral obstruction (Disease Ontology:DOID:5199); lung small cell carcinoma (Disease Ontology:DOID:5409); schizophrenia (Disease Ontology:DOID:5419); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); pulmonary hypertension (Disease Ontology:DOID:6432); hepatocellular carcinoma (Disease Ontology:DOID:684); muscular atrophy (Disease Ontology:DOID:767); end stage renal disease (Disease Ontology:DOID:783); kidney angiomyolipoma (Disease Ontology:DOID:8411); vascular dementia (Disease Ontology:DOID:8725); autosomal dominant polycystic kidney disease (Disease Ontology:DOID:898); type 2 diabetes mellitus (Disease Ontology:DOID:9352); obesity (Disease Ontology:DOID:9970)", "pathway": " (sce:YKL203C); (R-SCE-1257604); (R-SCE-3371571); (R-SCE-389357); (R-SCE-5218920); (R-SCE-6804757); (R-SCE-9639288); (R-SCE-9856530)", "pathway_count": 8, "publication_count": 36, "publication_id_list": "10198052;10329624;10604478;10973982;11741537;12408816;12631735;14593073;15372071;15620355;15689497;16002396;16055732;16959779;17560372;18407956;19779198;20489023;21126336;24374639;25767889;29170376;29698392;32597660;33481703;33491328;7606777;8186460;8196765;8387896;8654975;8741837;8846782;8943012;9539725;9843498", "class_list": "", "function": "Phosphatidylinositol 3-kinase homolog, component of both TORC1 and TORC2. TORC1 regulates multiple cellular processes to control cell growth in response to environmental signals. Nutrient limitation and environmental stress signals cause inactivation of TORC1. Active TORC1 positively controls ribosome biogenesis via control of rRNA, ribosomal protein and tRNA gene expression, and rRNA processing. TORC1 positively controls protein biosynthesis by regulation of mRNA stability, translation initiation factor activity, and high-affinity amino acid permeases that serve to provide amino acids for use by the translation machinery. TORC1 also promotes growth by sequestering a number of nutrient and general stress-responsive transcription factors in the cytoplasm. TORC1 negatively controls macroautophagy, a process to recycle surplus cytoplasmic mass under nutrient starvation conditions. TORC1 controls many of these processes via TIP41-TAP42-mediated inhibition of the type 2A-related phosphatases PP2A and SIT4 (PubMed:10198052, PubMed:10329624, PubMed:10604478, PubMed:11741537, PubMed:15620355, PubMed:7606777, PubMed:8741837, PubMed:9539725, PubMed:9843498). In nutrient-rich conditions, responsible for the phosphorylation of AGC S6 kinase (S6K) YPK3, activating YPK3 kinase activity and promoting phosphorylation of ribosomal protein S6 (PubMed:25767889). Phosphorylates kinase SCH9 at 6 amino acids in the C-terminus, activating SCH9 kinase activity to properly regulate ribosome biogenesis, translation initiation, and entry into stationary phase (PubMed:17560372). TORC2 regulates cell cycle-dependent polarization of the actin-cytoskeleton, cell wall integrity, and receptor endocytosis. TORC2 controls polarity of the actin cytoskeleton, which is required for orienting the secretory pathway toward discrete growth sites, via the RHO1/PKC1/MAPK cell integrity pathway by activating the RHO1 guanine nucleotide exchange factor ROM2. TORC2 phosphorylates the AGC kinase YPK2, an upstream effector of the cell integrity pathway. TORC2 negatively regulates calcineurin-dependent stress signaling via phosphorylation of its effector SLM1-SLM2 (PubMed:14593073, PubMed:15372071, PubMed:16055732, PubMed:16959779, PubMed:8846782, PubMed:8943012)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 19, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 34, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VX00", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;3.1.-.-;7.1.2.2;2.7.11.17;2.7.11.23;2.7.11.25;2.7.11.13;3.6.5.-;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0044877 protein-containing complex binding;GO:0004430 1-phosphatidylinositol 4-kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005886 plasma membrane;GO:0031931 TORC1 complex", "go_biological_process": "GO:0007584 response to nutrient;GO:0007010 cytoskeleton organization;GO:0042254 ribosome biogenesis;GO:0001558 regulation of cell growth;GO:0010507 negative regulation of autophagy", "synthesized_glycan_count": 0, "hit_score": 3.7, "record_id": "P32600-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32622-1", "uniprot_id": "YEF1_YEAST", "mass": 55874.0, "length": 495, "protein_name": "ATP-NADH kinase YEF1", "gene_name": "YEF1", "organism": "Yeast", "refseq_name": "NADH/NAD(+) kinase", "refseq_ac": "NP_010873", "gene_names_uniprotkb": "YEF1; SYGP-ORF17", "gene_names_refseq": "YEF1", "protein_names_uniprotkb": "ATP-NADH kinase YEF1; 2.7.1.86", "protein_names_refseq": "NADH/NAD(+) kinase", "tax_id": 559292, "disease": "", "pathway": " (sce:YEL041W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562106;15978040;16760478;19158096;19779198;24374639;33491328;9169868", "class_list": "", "function": "ATP-NADH kinase with a low phosphorylation activity of both NADH and NAD(+) to produce NADP and NADPH by using ATP. UTR1 is responsible for essentially all of the NAD/NADH kinase activity resident in the cytoplasm, whereas POS5 is responsible for all mitochondrial NAD/NADH kinase activity and consequent mitochondrial genome maintenance. YEF1 can substitute for UTR1 when overexpressed., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLK8", "ec_number_list": "2.7.1.86", "go_molecular_function": "GO:0003951 NAD+ kinase activity;GO:0005524 ATP binding;GO:0042736 NADH kinase activity", "go_cellular_component": "", "go_biological_process": "GO:0006741 NADP+ biosynthetic process;GO:0019674 NAD+ metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P32622-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32642-1", "uniprot_id": "GLRX4_YEAST", "mass": 27493.0, "length": 244, "protein_name": "Monothiol glutaredoxin-4", "gene_name": "GRX4", "organism": "Yeast", "refseq_name": "monothiol glutaredoxin GRX4", "refseq_ac": "NP_011101", "gene_names_uniprotkb": "GRX4; SYGP-ORF64", "gene_names_refseq": "GRX4", "protein_names_uniprotkb": "Monothiol glutaredoxin-4", "protein_names_refseq": "monothiol glutaredoxin GRX4", "tax_id": 559292, "disease": "", "pathway": " (sce:YER174C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "14519092;14562106;18281282;19021767;19715344;19795423;19823750;23749301;24374639;33491328;9169868", "class_list": "", "function": "Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters (By similarity). Binds one iron-sulfur cluster per dimer. The iron-sulfur cluster is bound between subunits, and is complexed by a bound glutathione and a cysteine residue from each subunit (Probable)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DM82", "ec_number_list": "", "go_molecular_function": "GO:0004364 glutathione transferase activity;GO:0015036 disulfide oxidoreductase activity;GO:0046872 metal ion binding;GO:0051537 2 iron, 2 sulfur cluster binding;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:1990229 iron-sulfur cluster assembly complex", "go_biological_process": "GO:0016226 iron-sulfur cluster assembly;GO:0006879 intracellular iron ion homeostasis;GO:0030036 actin cytoskeleton organization;GO:0034599 cellular response to oxidative stress", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P32642-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32774-1", "uniprot_id": "T2AG_YEAST", "mass": 13458.0, "length": 122, "protein_name": "Transcription initiation factor IIA subunit 2", "gene_name": "TOA2", "organism": "Yeast", "refseq_name": "transcription initiation factor IIA subunit gamma", "refseq_ac": "NP_012865", "gene_names_uniprotkb": "TOA2", "gene_names_refseq": "TOA2", "protein_names_uniprotkb": "Transcription initiation factor IIA subunit 2; General transcription factor IIA subunit 2; TFIIA 13.5 kDa subunit; Transcription initiation factor IIA small chain; Transcription initiation factor IIA small subunit", "protein_names_refseq": "transcription initiation factor IIA subunit gamma", "tax_id": 559292, "disease": "", "pathway": " (sce:YKL058W); (R-SCE-674695); (R-SCE-6807505); (R-SCE-73776); (R-SCE-73779); (R-SCE-75953); (R-SCE-76042); (R-SCE-9018519)", "pathway_count": 8, "publication_count": 19, "publication_id_list": "10525531;11238911;14562106;1546313;17322287;17563356;18407956;1918049;19779198;20190278;22218487;23749301;24374639;32597660;33481703;33491328;8091862;8196765;8610010", "class_list": "", "function": "TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXM9", "ec_number_list": "", "go_molecular_function": "GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding;GO:0017025 TBP-class protein binding;GO:0016251 RNA polymerase II general transcription initiation factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005672 transcription factor TFIIA complex", "go_biological_process": "GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter;GO:0051123 RNA polymerase II preinitiation complex assembly", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P32774-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32790-1", "uniprot_id": "SLA1_YEAST", "mass": 135848.0, "length": 1244, "protein_name": "Actin cytoskeleton-regulatory complex protein SLA1", "gene_name": "SLA1", "organism": "Yeast", "refseq_name": "cytoskeletal protein-binding protein SLA1", "refseq_ac": "NP_009546", "gene_names_uniprotkb": "SLA1; YBL0321", "gene_names_refseq": "SLA1", "protein_names_uniprotkb": "Actin cytoskeleton-regulatory complex protein SLA1", "protein_names_refseq": "cytoskeletal protein-binding protein SLA1", "tax_id": 559292, "disease": "", "pathway": " (sce:YBL007C)", "pathway_count": 1, "publication_count": 49, "publication_id_list": "10198057;10594004;11739778;11940605;11950888;12237851;12388763;12734398;12814545;1441753;14562095;14562106;14761940;15265985;15525671;15651983;15665377;17286805;17330950;17363896;17563356;17765920;17978096;18407956;19684113;19779198;19795423;19823750;20489023;20702584;21126336;21177495;22106047;22218487;22814378;23749301;24374639;24909858;30516470;32597660;33229814;33481703;33491328;7813418;8335689;8756649;9008707;9024694;9128251", "class_list": "", "function": "Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 13, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 13, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 13, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 66, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 13, "binding_glycan_count": 0, "secondary_ac_list": "D6VPZ3", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0042802 identical protein binding;GO:0008289 lipid binding;GO:0043130 ubiquitin binding;GO:0140312 cargo adaptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0010008 endosome membrane", "go_biological_process": "GO:0006897 endocytosis;GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation;GO:0030833 regulation of actin filament polymerization;GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation;GO:0000147 actin cortical patch assembly", "synthesized_glycan_count": 0, "hit_score": 6.4, "record_id": "P32790-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32793-1", "uniprot_id": "YSC84_YEAST", "mass": 50902.0, "length": 468, "protein_name": "Protein YSC84", "gene_name": "YSC84", "organism": "Yeast", "refseq_name": "Ysc84p", "refseq_ac": "NP_011880", "gene_names_uniprotkb": "YSC84; LSB4", "gene_names_refseq": "LSB4; YSC84", "protein_names_uniprotkb": "Protein YSC84; LAS seventeen-binding protein 4; LAS17-binding protein 4", "protein_names_refseq": "Ysc84p", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR016C)", "pathway_count": 1, "publication_count": 21, "publication_id_list": "10512884;11875433;12388763;17330950;17563356;18407956;19779198;19795423;19823750;20702584;21126336;21177495;22218487;23749301;24374639;27821475;32597660;33481703;33491328;8091229;8256520", "class_list": "", "function": "Essential for the organization of the actin cytoskeleton, fluid phase endocytosis and vesicle trafficking, together with LSB5., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 18, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DKW1", "ec_number_list": "", "go_molecular_function": "GO:0051015 actin filament binding;GO:0035091 phosphatidylinositol binding", "go_cellular_component": "GO:0005829 cytosol;GO:0030479 actin cortical patch", "go_biological_process": "GO:0006897 endocytosis;GO:0030036 actin cytoskeleton organization;GO:0051017 actin filament bundle assembly;GO:0051666 actin cortical patch localization", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P32793-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32795-1", "uniprot_id": "YME1_YEAST", "mass": 81772.0, "length": 747, "protein_name": "Mitochondrial inner membrane i-AAA protease supercomplex subunit YME1", "gene_name": "YME1", "organism": "Yeast", "refseq_name": "i-AAA protease YME1", "refseq_ac": "NP_015349", "gene_names_uniprotkb": "YME1; OSD1; YP9367.04; YTA11", "gene_names_refseq": "OSD1; YME1; YTA11", "protein_names_uniprotkb": "Mitochondrial inner membrane i-AAA protease supercomplex subunit YME1; 3.4.24.-; Protein OSD1; Tat-binding homolog 11; Yeast mitochondrial escape protein 1", "protein_names_refseq": "i-AAA protease YME1", "tax_id": 559292, "disease": "colorectal adenocarcinoma (Disease Ontology:DOID:0050861); optic atrophy 11 (Disease Ontology:DOID:0111436); dilated cardiomyopathy (Disease Ontology:DOID:12930); mitochondrial metabolism disease (Disease Ontology:DOID:700)", "pathway": " (sce:YPR024W); (R-SCE-9840373)", "pathway_count": 2, "publication_count": 14, "publication_id_list": "14562095;14562106;16267274;16527490;18843051;24374639;32597660;33491328;38964378;7623837;7754704;8355690;8688560;9169875", "class_list": "", "function": "Catalytic subunit of the mitochondrial inner membrane i-AAA protease supercomplex required for mitochondrial inner membrane protein turnover. The protease is probably ATP-dependent. Important to maintain the integrity of the mitochondrial compartment. Required both for the degradation of unassembled subunit 2 of cytochrome c oxidase (COX2) and for efficient assembly of mitochondrial respiratory chain. Binds unfolded substrates in an ATPase-independent manner; binding of folded COX2, a physiological substrate, requires an active ATPase but when COX2 is destabilized an active ATPase is no longer necessary (PubMed:16267274, PubMed:16527490). May process ATG32 (PubMed:38964378)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 19, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W434", "ec_number_list": "7.1.1.9;3.4.24.-", "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0004176 ATP-dependent peptidase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0031942 i-AAA complex", "go_biological_process": "GO:0045041 protein import into mitochondrial intermembrane space;GO:0006457 protein folding;GO:0007005 mitochondrion organization;GO:0030163 protein catabolic process;GO:0051604 protein maturation", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P32795-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32797-1", "uniprot_id": "CDC13_YEAST", "mass": 104904.0, "length": 924, "protein_name": "Cell division control protein 13", "gene_name": "CDC13", "organism": "Yeast", "refseq_name": "telomere-binding protein CDC13", "refseq_ac": "NP_010061", "gene_names_uniprotkb": "CDC13", "gene_names_refseq": "CDC13; EST4", "protein_names_uniprotkb": "Cell division control protein 13", "protein_names_refseq": "telomere-binding protein CDC13", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL220C)", "pathway_count": 1, "publication_count": 28, "publication_id_list": "10898792;11230140;11230149;11390652;11935027;12207228;14562106;15066429;17108359;17287358;17563356;18407956;19135888;19359360;19779198;19795423;19823750;20194442;20702584;20837994;23749301;24164896;24374639;32597660;33481703;33491328;7565765;9169867", "class_list": "", "function": "Single-stranded telomeric DNA-binding protein that regulates telomere replication. Has a role in both positive and negative regulation. Promotes [TG(1-3)] strand lengthening via interaction with EST1. Promotes [C(1-3)A] strand re-synthesis by DNA polymerase alpha via interaction with POL1. Negatively regulates telomere elongation of the G strand via binding with STN1 thereby inhibiting telomerase activity., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 23, "reported_mutagensis": 8, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRD4;Q07650", "ec_number_list": "", "go_molecular_function": "GO:0098505 G-rich strand telomeric DNA binding;GO:0042802 identical protein binding;GO:0043047 single-stranded telomeric DNA binding;GO:0061770 translation elongation factor binding;GO:0010521 telomerase inhibitor activity", "go_cellular_component": "GO:0000783 nuclear telomere cap complex;GO:0000781 chromosome, telomeric region;GO:1990879 CST complex", "go_biological_process": "GO:0051301 cell division;GO:0000723 telomere maintenance;GO:0016233 telomere capping;GO:0071166 ribonucleoprotein complex localization;GO:0032210 regulation of telomere maintenance via telomerase", "synthesized_glycan_count": 0, "hit_score": 2.9, "record_id": "P32797-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32830-1", "uniprot_id": "TIM12_YEAST", "mass": 12284.0, "length": 109, "protein_name": "Mitochondrial import inner membrane translocase subunit TIM12", "gene_name": "TIM12", "organism": "Yeast", "refseq_name": "Tim12p", "refseq_ac": "NP_009649", "gene_names_uniprotkb": "TIM12; MRS5; YBR0812", "gene_names_refseq": "MRS5; TIM12", "protein_names_uniprotkb": "Mitochondrial import inner membrane translocase subunit TIM12; Mitochondrial regulator of splicing 5", "protein_names_refseq": "Tim12p", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR091C)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10369662;10648604;10995434;12637749;17322287;22814378;22984289;24374639;7813418;7900426;8663351;8955274;9430585;9495346;9889188", "class_list": "", "function": "Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force. In the TIM22 complex, it acts as a docking point for the soluble TIM9-TIM10 heterohexamer that guides the target proteins in transit through the aqueous mitochondrial intermembrane space., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQ92", "ec_number_list": "", "go_molecular_function": "GO:0005543 phospholipid binding;GO:0046872 metal ion binding;GO:0032977 membrane insertase activity", "go_cellular_component": "GO:0042719 mitochondrial intermembrane space chaperone complex;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0042721 TIM22 mitochondrial import inner membrane insertion complex", "go_biological_process": "GO:0045039 protein insertion into mitochondrial inner membrane;GO:0071806 protein transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P32830-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32835-1", "uniprot_id": "GSP1_YEAST", "mass": 24810.0, "length": 219, "protein_name": "GTP-binding nuclear protein GSP1/CNR1", "gene_name": "GSP1", "organism": "Yeast", "refseq_name": "Ran GTPase GSP1", "refseq_ac": "NP_013396", "gene_names_uniprotkb": "GSP1; CNR1; CST17; L8003.19", "gene_names_refseq": "CNR1; CST17; GSP1", "protein_names_uniprotkb": "GTP-binding nuclear protein GSP1/CNR1; Chromosome stability protein 17; GTPase Ran homolog; Genetic suppressor of PRP20-1", "protein_names_refseq": "Ran GTPase GSP1", "tax_id": 559292, "disease": "sciatic neuropathy (Disease Ontology:DOID:11446); type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": " (sce:YLR293C); (R-SCE-9615933)", "pathway_count": 2, "publication_count": 21, "publication_id_list": "10921930;11523802;11589573;14729571;15665377;17203074;17322287;18407956;19779198;19795423;19823750;21126336;24374639;29146254;33491328;39601790;7687541;7895733;8455603;8896453;9169871", "class_list": "", "function": "GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. By analogy with Ras, Ran may be activated when GTP is exchanged for bound GDP by RCC1 and inactivated when GTP is hydrolyzed by Ran upon activation by RanGAP1. Also participates in nucleosome assembly by stimulating the release of histone H2A-H2B dimers from their nuclear import chaperone KAP114, to facilitate their deposition into nucleosomes by NAP1 (PubMed:39601790)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYT9", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0016973 poly(A)+ mRNA export from nucleus;GO:0046822 regulation of nucleocytoplasmic transport;GO:0000054 ribosomal subunit export from nucleus;GO:0006334 nucleosome assembly;GO:1901987 regulation of cell cycle phase transition", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P32835-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32841-1", "uniprot_id": "RE114_YEAST", "mass": 48706.0, "length": 428, "protein_name": "Meiotic recombination protein REC114", "gene_name": "REC114", "organism": "Yeast", "refseq_name": "Rec114p", "refseq_ac": "NP_013852", "gene_names_uniprotkb": "REC114; YM9375.02", "gene_names_refseq": "REC114", "protein_names_uniprotkb": "Meiotic recombination protein REC114", "protein_names_refseq": "Rec114p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR133W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "10526232;14992724;15655113;16783010;24374639;8385581;9169872;9177999;9267437", "class_list": "", "function": "Required for the production of double-strand breaks (DSBs) in meiotic recombination initiation; not required for mitosis. Plays a role in activation of the DSB nuclease SPO11 at recombination hotspots. Prevents accumulation of meiotic double strand break intermediates and is needed for the proper timing of the first meiotic division. Component of the MER2-MEI4-REC114 complex which seems to be required for meiotic double-strand break (DSB) formation., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZV6", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0005634 nucleus", "go_biological_process": "GO:0042138 meiotic DNA double-strand break formation;GO:0007131 reciprocal meiotic recombination", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P32841-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32844-1", "uniprot_id": "SEC6_YEAST", "mass": 93428.0, "length": 805, "protein_name": "Exocyst complex component SEC6", "gene_name": "SEC6", "organism": "Yeast", "refseq_name": "SNARE-binding exocyst subunit SEC6", "refseq_ac": "NP_012196", "gene_names_uniprotkb": "SEC6", "gene_names_refseq": "SEC6", "protein_names_uniprotkb": "Exocyst complex component SEC6", "protein_names_refseq": "SNARE-binding exocyst subunit SEC6", "tax_id": 559292, "disease": "focal segmental glomerulosclerosis (Disease Ontology:DOID:1312)", "pathway": " (sce:YIL068C); (R-SCE-264876)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "14562106;1523887;16699513;22814378;24374639;33491328;9169870", "class_list": "", "function": "Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVL6", "ec_number_list": "", "go_molecular_function": "GO:0000149 SNARE binding", "go_cellular_component": "GO:0000145 exocyst;GO:0005628 prospore membrane;GO:0005934 cellular bud tip;GO:0005935 cellular bud neck;GO:0043332 mating projection tip", "go_biological_process": "GO:0051601 exocyst localization;GO:0015031 protein transport;GO:0035544 negative regulation of SNARE complex assembly;GO:0006887 exocytosis;GO:0006893 Golgi to plasma membrane transport", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P32844-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32867-1", "uniprot_id": "SSO1_YEAST", "mass": 33106.0, "length": 290, "protein_name": "Protein SSO1", "gene_name": "SSO1", "organism": "Yeast", "refseq_name": "syntaxin", "refseq_ac": "NP_015092", "gene_names_uniprotkb": "SSO1; P1405", "gene_names_refseq": "SSO1", "protein_names_uniprotkb": "Protein SSO1", "protein_names_refseq": "syntaxin", "tax_id": 559292, "disease": "autosomal recessive nonsyndromic deafness (Disease Ontology:DOID:0050565); congenital diarrhea (Disease Ontology:DOID:0060774); familial hemophagocytic lymphohistiocytosis 4 (Disease Ontology:DOID:0110924); generalized epilepsy with febrile seizures plus 9 (Disease Ontology:DOID:0111301); Hirschsprung's disease (Disease Ontology:DOID:10487); Creutzfeldt-Jakob disease (Disease Ontology:DOID:11949); disease of mental health (Disease Ontology:DOID:150); epilepsy (Disease Ontology:DOID:1826); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (sce:YPL232W); (R-SCE-114516); (R-SCE-199992); (R-SCE-204005); (R-SCE-9609523)", "pathway_count": 5, "publication_count": 14, "publication_id_list": "11157748;12006655;12925750;14562106;18407956;19779198;20948969;23749301;24374639;2900835;33481703;33491328;8223426;9169875", "class_list": "", "function": "Required for vesicle fusion with the plasma membrane., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3D8", "ec_number_list": "", "go_molecular_function": "GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0043325 phosphatidylinositol-3,4-bisphosphate binding;GO:0080025 phosphatidylinositol-3,5-bisphosphate binding;GO:0000149 SNARE binding;GO:0070300 phosphatidic acid binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005886 plasma membrane;GO:0012505 endomembrane system;GO:0071944 cell periphery;GO:0031201 SNARE complex", "go_biological_process": "GO:0048210 Golgi vesicle fusion to target membrane;GO:0006886 intracellular protein transport;GO:0006887 exocytosis;GO:0035493 SNARE complex assembly;GO:0006893 Golgi to plasma membrane transport", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P32867-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32910-1", "uniprot_id": "RPC6_YEAST", "mass": 36135.0, "length": 317, "protein_name": "DNA-directed RNA polymerase III subunit RPC6", "gene_name": "RPC34", "organism": "Yeast", "refseq_name": "DNA-directed RNA polymerase III subunit C34", "refseq_ac": "NP_014400", "gene_names_uniprotkb": "RPC34; N2031", "gene_names_refseq": "RPC34", "protein_names_uniprotkb": "DNA-directed RNA polymerase III subunit RPC6; C34; DNA-directed RNA polymerase III 36 kDa polypeptide; RNA polymerase III subunit C6", "protein_names_refseq": "DNA-directed RNA polymerase III subunit C34", "tax_id": 559292, "disease": "immunodeficiency 101 (Disease Ontology:DOID:0061071)", "pathway": " (sce:YNR003C); (R-SCE-76061); (R-SCE-76066)", "pathway_count": 3, "publication_count": 8, "publication_id_list": "10384303;1400451;24374639;7900425;7941739;8407894;9169873;9312031", "class_list": "", "function": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Involved in recruitment of Pol III to the preinitiation complex. Involved in the configuration of an initiation-competent form of RNA polymerase., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1H9", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005666 RNA polymerase III complex", "go_biological_process": "GO:0042797 tRNA transcription by RNA polymerase III;GO:0006383 transcription by RNA polymerase III;GO:0006386 termination of RNA polymerase III transcription;GO:0006384 transcription initiation at RNA polymerase III promoter", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P32910-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32912-1", "uniprot_id": "VAM7_YEAST", "mass": 36711.0, "length": 316, "protein_name": "Vacuolar morphogenesis protein 7", "gene_name": "VAM7", "organism": "Yeast", "refseq_name": "Vam7p", "refseq_ac": "NP_011303", "gene_names_uniprotkb": "VAM7", "gene_names_refseq": "VAM7; VPL24; VPS43", "protein_names_uniprotkb": "Vacuolar morphogenesis protein 7", "protein_names_refseq": "Vam7p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL212W)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "14562106;1526999;19684113;19779198;19795423;19823750;21126336;22814378;23749301;24374639;32597660;33491328;8813766;9153757;9169869;9710615", "class_list": "", "function": "Essential for proper morphogenesis of the vacuole. May exist as structural reinforcement on the surface of the vacuolar membrane and be required for maintenance against rupture by osmotic pressure., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTU3", "ec_number_list": "", "go_molecular_function": "GO:0000149 SNARE binding;GO:0032266 phosphatidylinositol-3-phosphate binding;GO:0070300 phosphatidic acid binding;GO:0005484 SNAP receptor activity", "go_cellular_component": "GO:0000421 autophagosome membrane;GO:0012505 endomembrane system;GO:0005774 vacuolar membrane;GO:0000407 phagophore assembly site;GO:0031201 SNARE complex", "go_biological_process": "GO:0042144 vacuole fusion, non-autophagic;GO:0006886 intracellular protein transport;GO:0016236 macroautophagy;GO:0034727 piecemeal microautophagy of the nucleus;GO:0032258 cytoplasm to vacuole targeting by the Cvt pathway", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P32912-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32914-1", "uniprot_id": "SPT4_YEAST", "mass": 11158.0, "length": 102, "protein_name": "Transcription elongation factor SPT4", "gene_name": "SPT4", "organism": "Yeast", "refseq_name": "transcription elongation factor SPT4", "refseq_ac": "NP_011577", "gene_names_uniprotkb": "SPT4", "gene_names_refseq": "SPT4", "protein_names_uniprotkb": "Transcription elongation factor SPT4; Chromatin elongation factor SPT4", "protein_names_refseq": "transcription elongation factor SPT4", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR063C); (R-SCE-113418); (R-SCE-674695); (R-SCE-6796648)", "pathway_count": 4, "publication_count": 23, "publication_id_list": "12554661;12556496;14562106;15057281;15780939;16172632;16951060;17322287;19683497;20713510;24374639;27376968;29155810;31462158;33491328;33809333;33846633;36640349;39424994;8483459;8649393;9169869;9450930", "class_list": "", "function": "Component of the SPT4-SPT5 (DISF) complex that manipulates multiple stages of transcription from promoter- proximal pausing (PPP) to termination (PubMed:12554661, PubMed:12556496, PubMed:15780939, PubMed:33846633, PubMed:8483459, PubMed:9450930). Mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing (PubMed:12556496, PubMed:16172632, PubMed:33846633, PubMed:8483459, PubMed:9450930). Binds to single stranded RNA containing AAN repeats in a sequence-specific manner (PubMed:27376968). The complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (PubMed:12554661, PubMed:15780939). Promotes also RNA polymerase I processivity and enhances transcription elongation of the rDNA through regions of the ribosomal DNA that are particularly G-rich (PubMed:33809333). Structural and functional component of the centromeric and heterochromatic loci linking chromatin structure with kinetochore function and gene silencing (PubMed:15057281). SPT4 acts as an aging factor that accelerates cellular senescence through rDNA instability driven by non-coding RNA transcription (PubMed:36640349). Finally, the SPT4-SPT5 complex also negatively regulates the expression of ATG8 and ATG41, inhibiting autophagy activity during active growth. Under autophagy-inducing conditions, the repression is released by SPT5 phosphorylation, allowing an up-regulation of autophagy activity (PubMed:31462158)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUJ8;Q0P6T7;Q45U23", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0044877 protein-containing complex binding;GO:0000993 RNA polymerase II complex binding;GO:0000182 rDNA binding", "go_cellular_component": "GO:0032044 DSIF complex;GO:0005634 nucleus;GO:0000776 kinetochore;GO:0033553 rDNA heterochromatin;GO:0031934 mating-type region heterochromatin", "go_biological_process": "GO:2000232 regulation of rRNA processing;GO:0006355 regulation of DNA-templated transcription;GO:0010507 negative regulation of autophagy;GO:0006325 chromatin organization;GO:0006368 transcription elongation by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P32914-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32944-1", "uniprot_id": "SWE1_YEAST", "mass": 92468.0, "length": 819, "protein_name": "Mitosis inhibitor protein kinase SWE1", "gene_name": "SWE1", "organism": "Yeast", "refseq_name": "tyrosine protein kinase SWE1", "refseq_ac": "NP_012348", "gene_names_uniprotkb": "SWE1; J0406", "gene_names_refseq": "SWE1; WEE1", "protein_names_uniprotkb": "Mitosis inhibitor protein kinase SWE1; 2.7.11.1; Wee1 homolog", "protein_names_refseq": "tyrosine protein kinase SWE1", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL187C); (R-SCE-156711)", "pathway_count": 2, "publication_count": 41, "publication_id_list": "10454545;10490630;10490648;10619027;10805747;11283616;11404321;11408575;11438652;12388757;12593792;12773812;12840070;14565980;14574415;15037762;15118337;15282802;15920482;15956196;16096060;16360682;16571676;17563356;17614281;18407956;19779198;20489023;22106047;23749301;24374639;26332045;32597660;33481703;33491328;8253069;8641269;8647431;8930890;9716410;9822611", "class_list": "", "function": "Protein kinase that acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylating and inhibiting the mitosis-promoting cyclin B-bound CDC28 at 'Tyr-19'. SWE1-mediated inhibition of CDC28 acts in a cell size or morphogenesis checkpoint to delay mitosis in response to defects in growth, actin organization or bud formation. Inhibits the activity of B-type cyclins in replication initiation strongly for CLB2, moderately for CLB3 and CLB4, and there is no apparent inhibition for CLB5 and CLB6, correlating with the normal expression timing of those cyclins. Hyperphosphorylation and degradation of SWE1 when all checkpoint requirement are met releases CLB2-CDC28 from inhibition and allows for progression through the cell cycle. SWE1-dependent CDC28 phosphorylation is also required for pachytene arrest upon activation of the recombination checkpoint during meiosis. Also involved in the regulation of nitrogen starvation- and short chain alcohol-induced filamentous growth, or filamentous differentiation in response to slowed DNA synthesis. Can act both on serines and on tyrosines., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 69, "reported_mutagensis": 18, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VW03", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005935 cellular bud neck", "go_biological_process": "GO:0051301 cell division;GO:0000086 G2/M transition of mitotic cell cycle;GO:0010972 negative regulation of G2/M transition of mitotic cell cycle;GO:0051321 meiotic cell cycle;GO:0000320 re-entry into mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 4.2, "record_id": "P32944-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P33202-1", "uniprot_id": "UFD4_YEAST", "mass": 167843.0, "length": 1483, "protein_name": "Ubiquitin fusion degradation protein 4", "gene_name": "UFD4", "organism": "Yeast", "refseq_name": "putative ubiquitin-protein ligase UFD4", "refseq_ac": "NP_012915", "gene_names_uniprotkb": "UFD4; YKL162", "gene_names_refseq": "UFD4", "protein_names_uniprotkb": "Ubiquitin fusion degradation protein 4; 2.3.2.-; 2.3.2.26; HECT-type E3 ubiquitin transferase UFD4; UB fusion protein 4", "protein_names_refseq": "putative ubiquitin-protein ligase UFD4", "tax_id": 559292, "disease": "Clark-Baraitser syndrome (Disease Ontology:DOID:0080234); cancer (Disease Ontology:DOID:162)", "pathway": " (sce:YKL010C); (R-SCE-983168)", "pathway_count": 2, "publication_count": 18, "publication_id_list": "14562106;1481574;17330950;17563356;18407956;19779198;20489023;20702584;21177495;22031224;22106047;23749301;24374639;32597660;33481703;33491328;7615550;8196765", "class_list": "", "function": "E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXS6", "ec_number_list": "2.3.2.23;2.3.2.27;6.2.1.45;2.3.2.-;2.3.2.26;2.3.2.31;1.14.11.27;2.3.2.34;6.3.2.-", "go_molecular_function": "GO:0061630 ubiquitin protein ligase activity;GO:1904855 proteasome regulatory particle binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0016607 nuclear speck", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0000209 protein polyubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0010994 free ubiquitin chain polymerization;GO:0035519 protein K29-linked ubiquitination", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P33202-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P33299-1", "uniprot_id": "PRS7_YEAST", "mass": 51983.0, "length": 467, "protein_name": "26S proteasome regulatory subunit 7 homolog", "gene_name": "RPT1", "organism": "Yeast", "refseq_name": "proteasome regulatory particle base subunit RPT1", "refseq_ac": "NP_012777", "gene_names_uniprotkb": "RPT1; CIM5; YTA3", "gene_names_refseq": "CIM5; RPT1; YTA3", "protein_names_uniprotkb": "26S proteasome regulatory subunit 7 homolog; Protein CIM5; Tat-binding homolog 3", "protein_names_refseq": "proteasome regulatory particle base subunit RPT1", "tax_id": 559292, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (sce:YKL145W); (R-SCE-1236978); (R-SCE-5668541); (R-SCE-5689880); (R-SCE-6798695); (R-SCE-9907900)", "pathway_count": 6, "publication_count": 18, "publication_id_list": "10688918;11500370;12504901;14562095;14562106;17563356;18407956;20486117;22927375;23749301;24374639;30516470;32597660;33481703;33491328;7754704;8196765;8247132", "class_list": "", "function": "The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VX51", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0031625 ubiquitin protein ligase binding;GO:0036402 proteasome-activating activity", "go_cellular_component": "GO:0008540 proteasome regulatory particle, base subcomplex;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045732 positive regulation of protein catabolic process;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0070682 proteasome regulatory particle assembly;GO:0045899 positive regulation of RNA polymerase II transcription preinitiation complex assembly", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P33299-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P33306-1", "uniprot_id": "BCK2_YEAST", "mass": 93738.0, "length": 851, "protein_name": "Protein BCK2", "gene_name": "BCK2", "organism": "Yeast", "refseq_name": "Bck2p", "refseq_ac": "NP_011094", "gene_names_uniprotkb": "BCK2; CTR7", "gene_names_refseq": "BCK2; CTR7", "protein_names_uniprotkb": "Protein BCK2; Bypass of kinase C protein", "protein_names_refseq": "Bck2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YER167W)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "17287358;18407956;19779198;19795423;19823750;20489023;21177495;23749301;24374639;28270554;31208443;32597660;33229814;33481703;33491328;8395014;9169868", "class_list": "", "function": "Dosage dependent suppressor of PKC1 deletion and MPK1 deletion. Involved in cell lysis., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 8, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 8, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 8, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 48, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "D3DM75", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0010628 positive regulation of gene expression;GO:0000082 G1/S transition of mitotic cell cycle;GO:0051726 regulation of cell cycle", "synthesized_glycan_count": 0, "hit_score": 2.7, "record_id": "P33306-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P33315-1", "uniprot_id": "TKT2_YEAST", "mass": 75029.0, "length": 681, "protein_name": "Transketolase 2", "gene_name": "TKL2", "organism": "Yeast", "refseq_name": "transketolase TKL2", "refseq_ac": "NP_009675", "gene_names_uniprotkb": "TKL2; YBR0912", "gene_names_refseq": "TKL2", "protein_names_uniprotkb": "Transketolase 2; 2.2.1.1; TK 2", "protein_names_refseq": "transketolase TKL2", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR117C)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14562106;24374639;7813418;7900426;7916691", "class_list": "", "function": "Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate (By similarity). Thus, catalyzes the reversible transfer of a two-carbon ketol group from sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate, producing xylulose-5-phosphate and ribose-5-phosphate (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQB5", "ec_number_list": "2.2.1.1", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004802 transketolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006098 pentose-phosphate shunt", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P33315-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P33323-1", "uniprot_id": "RE104_YEAST", "mass": 20744.0, "length": 182, "protein_name": "Meiotic recombination protein REC104", "gene_name": "REC104", "organism": "Yeast", "refseq_name": "Rec104p", "refseq_ac": "NP_012027", "gene_names_uniprotkb": "REC104", "gene_names_refseq": "REC104", "protein_names_uniprotkb": "Meiotic recombination protein REC104", "protein_names_refseq": "Rec104p", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR157W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "1304422;14992724;15044957;17322287;24374639;33481703;39304764;8091229;8462842", "class_list": "", "function": "Involved in double-strand break (DSB) formation during meiotic recombination by facilitating the formation of SPO11-mediated DNA double-strand breaks (DSBs)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLA6", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000794 condensed nuclear chromosome", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0042138 meiotic DNA double-strand break formation;GO:0007131 reciprocal meiotic recombination", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P33323-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P33329-1", "uniprot_id": "PPZ2_YEAST", "mass": 78492.0, "length": 710, "protein_name": "Serine/threonine-protein phosphatase PP-Z2", "gene_name": "PPZ2", "organism": "Yeast", "refseq_name": "salt homeostasis regulator", "refseq_ac": "NP_010724", "gene_names_uniprotkb": "PPZ2; D9461.22", "gene_names_refseq": "PPZ2", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase PP-Z2; 3.1.3.16", "protein_names_refseq": "salt homeostasis regulator", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR436W)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "14562106;1647215;17287358;17330950;17563356;18407956;19779198;19795423;19823750;20489023;20702584;23749301;24374639;28270554;32597660;33481703;33491328;8395014;8396031;9169867", "class_list": "", "function": "Essential for the maintenance of cell size and integrity in response to osmotic stress., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 46, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VT63", "ec_number_list": "3.1.3.16;3.1.3.43;3.1.3.48", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006883 intracellular sodium ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P33329-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P33754-1", "uniprot_id": "SEC66_YEAST", "mass": 24231.0, "length": 206, "protein_name": "Translocation protein SEC66", "gene_name": "SEC66", "organism": "Yeast", "refseq_name": "Sec63 complex subunit SEC66", "refseq_ac": "NP_009730", "gene_names_uniprotkb": "SEC66; HSS1; SEC71; YBR1232", "gene_names_refseq": "HSS1; KAR7; SEC66; SEC71", "protein_names_uniprotkb": "Translocation protein SEC66; Protein HSS1; Sec62/63 complex 31.5 kDa subunit", "protein_names_refseq": "Sec63 complex subunit SEC66", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR171W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562106;17322287;2000150;24374639;7758110;7813418;8212898;8253836;8257794;8257795", "class_list": "", "function": "Acts as a component of the Sec62/63 complex which is involved in SRP-independent post-translational translocation across the endoplasmic reticulum (ER) and functions together with the Sec61 complex and KAR2 in a channel-forming translocon complex. A cycle of assembly and disassembly of Sec62/63 complex from SEC61 may govern the activity of the translocon. SEC66 is required to attach or retain SEC72 in the SEC63 complex. It is essential for growth at elevated temperatures., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VQG7", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0071944 cell periphery;GO:0030867 rough endoplasmic reticulum membrane;GO:0031207 Sec62/Sec63 complex", "go_biological_process": "GO:0031204 post-translational protein targeting to membrane, translocation;GO:0030447 filamentous growth", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P33754-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P33755-1", "uniprot_id": "NPL4_YEAST", "mass": 65782.0, "length": 580, "protein_name": "Nuclear protein localization protein 4", "gene_name": "NPL4", "organism": "Yeast", "refseq_name": "nuclear protein localization protein 4", "refseq_ac": "NP_009729", "gene_names_uniprotkb": "NPL4; HRD4; YBR1231", "gene_names_refseq": "HRD4; NPL4", "protein_names_uniprotkb": "Nuclear protein localization protein 4; HMG-CoA reductase degradation protein 4", "protein_names_refseq": "nuclear protein localization protein 4", "tax_id": 559292, "disease": "neurodegenerative disease (Disease Ontology:DOID:1289)", "pathway": " (sce:YBR170C); (R-SCE-8951664); (R-SCE-9755511)", "pathway_count": 3, "publication_count": 18, "publication_id_list": "11598205;11733065;11739805;11740563;11847109;14562106;14636562;16427015;16873066;21070972;24374639;31249135;32597660;33481703;33491328;7813418;8212898;8930904", "class_list": "", "function": "Substrate-recruiting cofactor of the CDC48-NPL4-UFD1 segregase (PubMed:31249135). Assists CDC48 in the dislocation of misfolded, polyubiquitinated ERAD substrates that are subsequently delivered to the proteasome for degradation (PubMed:11739805, PubMed:11740563, PubMed:11847109). Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus (PubMed:11733065, PubMed:8930904). Required for the proteasome-dependent processing/activation of MGA2 and SPT23 transcription factors leading to the subsequent expression of OLE1 (PubMed:11733065). Regulates ubiquitin-mediated mitochondria protein degradation (PubMed:31249135). Involved in spindle disassembly probably by promoting the degradation of spindle assembly factors ASE1 and CDC5 at the end of mitosis (PubMed:14636562)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQG6", "ec_number_list": "", "go_molecular_function": "GO:0036435 K48-linked polyubiquitin modification-dependent protein binding;GO:0031625 ubiquitin protein ligase binding;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0030894 replisome;GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0072344 rescue of stalled ribosome;GO:0070651 nonfunctional rRNA decay;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0036503 ERAD pathway", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P33755-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P33760-1", "uniprot_id": "PEX6_YEAST", "mass": 115571.0, "length": 1030, "protein_name": "Peroxisomal ATPase PEX6", "gene_name": "PEX6", "organism": "Yeast", "refseq_name": "AAA family ATPase peroxin 6", "refseq_ac": "NP_014070", "gene_names_uniprotkb": "PEX6; N0310; PAS8", "gene_names_refseq": "PAS8; PEX6", "protein_names_uniprotkb": "Peroxisomal ATPase PEX6; 3.6.4.-; Peroxin-6; Peroxisomal assembly protein 8", "protein_names_refseq": "AAA family ATPase peroxin 6", "tax_id": 559292, "disease": "peroxisomal biogenesis disorder (Disease Ontology:DOID:0080377); peroxisome biogenesis disorder 4A (Disease Ontology:DOID:0080479); Heimler syndrome 2 (Disease Ontology:DOID:0080624); Peroxisome biogenesis disorder 4B (Disease Ontology:DOID:0081433); peroxisomal disease (Disease Ontology:DOID:906)", "pathway": " (sce:YNL329C)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "12808025;14562095;14562106;15634331;16007078;16911527;21665945;24374639;26066397;26170309;29321502;33491328;7645347;8241279;8533474;9169873", "class_list": "", "function": "Component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling (PubMed:15634331, PubMed:16007078, PubMed:16911527, PubMed:26066397, PubMed:26170309, PubMed:29321502). Specifically recognizes PEX5 monoubiquitinated at 'Cys-6', and pulls it out of the peroxisome lumen through the PEX2-PEX10-PEX12 retrotranslocation channel (PubMed:26066397, PubMed:26170309, PubMed:29321502). Extraction by the PEX1-PEX6 AAA ATPase complex is accompanied by unfolding of the TPR repeats and release of bound cargo from PEX5 (PubMed:29321502)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W0L8", "ec_number_list": "3.6.4.13;5.6.2.3;3.6.4.10;3.6.-.-;5.6.2.4;3.6.4.-;5.6.1.4;3.6.4.12;3.6.4.6;5.6.2.5;3.6.1.-;2.3.2.27;3.1.-.-;3.4.24.-;3.6.5.-;2.7.4.3;2.7.11.1;7.2.2.-", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140318 protein transporter activity", "go_cellular_component": "GO:0005777 peroxisome;GO:0005778 peroxisomal membrane;GO:0005829 cytosol;GO:1904949 ATPase complex", "go_biological_process": "GO:0043335 protein unfolding;GO:0016558 protein import into peroxisome matrix;GO:0016562 protein import into peroxisome matrix, receptor recycling", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P33760-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P34087-1", "uniprot_id": "RPB7_YEAST", "mass": 19058.0, "length": 171, "protein_name": "DNA-directed RNA polymerase II subunit RPB7", "gene_name": "RPB7", "organism": "Yeast", "refseq_name": "DNA-directed RNA polymerase II subunit RPB7", "refseq_ac": "NP_010692", "gene_names_uniprotkb": "RPB7; D9509.22", "gene_names_refseq": "RPB7", "protein_names_uniprotkb": "DNA-directed RNA polymerase II subunit RPB7; B16; RNA polymerase II subunit B7", "protein_names_refseq": "DNA-directed RNA polymerase II subunit RPB7", "tax_id": 559292, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (sce:YDR404C); (R-SCE-113418); (R-SCE-674695); (R-SCE-6781823); (R-SCE-6782135); (R-SCE-6782210); (R-SCE-6796648); (R-SCE-6807505); (R-SCE-72086); (R-SCE-72203); (R-SCE-73776); (R-SCE-73779); (R-SCE-75953); (R-SCE-76042); (R-SCE-77075); (R-SCE-9018519)", "pathway_count": 16, "publication_count": 16, "publication_id_list": "11087726;12746495;12907709;12914699;14562106;14580350;15304220;15591044;15610738;16341226;16765890;17056745;17875743;24374639;8488730;9169867", "class_list": "", "function": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RPB4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA. The RPB4-RPB7 subcomplex recruits FCP1 to Pol II., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VT36", "ec_number_list": "", "go_molecular_function": "GO:0003727 single-stranded RNA binding;GO:0003697 single-stranded DNA binding;GO:0031369 translation initiation factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000932 P-body;GO:0005665 RNA polymerase II, core complex", "go_biological_process": "GO:0006366 transcription by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter;GO:0006368 transcription elongation by RNA polymerase II;GO:0000956 nuclear-transcribed mRNA catabolic process;GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P34087-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P34216-1", "uniprot_id": "EDE1_YEAST", "mass": 150783.0, "length": 1381, "protein_name": "EH domain-containing and endocytosis protein 1", "gene_name": "EDE1", "organism": "Yeast", "refseq_name": "Ede1p", "refseq_ac": "NP_009506", "gene_names_uniprotkb": "EDE1; BUD15; YBL0501; YBL0520", "gene_names_refseq": "BUD15; EDE1", "protein_names_uniprotkb": "EH domain-containing and endocytosis protein 1; Bud site selection protein 15", "protein_names_refseq": "Ede1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YBL047C); (R-SCE-193648); (R-SCE-416482); (R-SCE-9013148); (R-SCE-9013406); (R-SCE-9013420)", "pathway_count": 6, "publication_count": 37, "publication_id_list": "10954428;11452010;11875433;12529323;14562095;14562106;15665377;16239147;16563434;17287358;17330950;17563356;18407956;18448668;19684113;19713939;19776351;19779198;19795423;19823750;20489023;20702584;21126336;21177495;22106047;22190733;22218487;23749301;24374639;30516470;32597660;33229814;33481703;33491328;7813418;7871888;8154187", "class_list": "", "function": "Functions at the internalization step of the clathrin-mediated endocytosis (CME) as an early-acting scaffold protein. Requires clathrin adapter proteins, ENT1/2 and YAP1801/2, for normal spatiotemporal dynamics and viability. Binds to biological membranes in a ubiquitin-dependent manner., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 9, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 9, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 9, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 116, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "D6VPV1", "ec_number_list": "", "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0005509 calcium ion binding;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030479 actin cortical patch;GO:0005934 cellular bud tip;GO:0005935 cellular bud neck", "go_biological_process": "GO:0006897 endocytosis;GO:0032880 regulation of protein localization;GO:0016197 endosomal transport;GO:0030968 endoplasmic reticulum unfolded protein response;GO:0032467 positive regulation of cytokinesis", "synthesized_glycan_count": 0, "hit_score": 4.8, "record_id": "P34216-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P34217-1", "uniprot_id": "PIN4_YEAST", "mass": 73776.0, "length": 668, "protein_name": "RNA-binding protein PIN4", "gene_name": "PIN4", "organism": "Yeast", "refseq_name": "Pin4p", "refseq_ac": "NP_009502", "gene_names_uniprotkb": "PIN4; MDT1; YBL0506; YBL0516", "gene_names_refseq": "MDT1; PIN4", "protein_names_uniprotkb": "RNA-binding protein PIN4; Psi inducibility protein 4", "protein_names_refseq": "Pin4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YBL051C)", "pathway_count": 1, "publication_count": 27, "publication_id_list": "14562095;14562106;15024067;15665377;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20489023;20702584;21126336;21177495;22218487;23749301;24374639;27821475;30516470;32597660;33229814;33481703;33491328;7813418;8154187", "class_list": "", "function": "Involved in normal G2/M phase transition of the mitotic cell cycle. In association with RAD53, also involved in checkpoint control in response to DNA damage., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 9, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 9, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 9, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 49, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "D6VPU8", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0000086 G2/M transition of mitotic cell cycle;GO:0000077 DNA damage checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 3.8, "record_id": "P34217-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P34223-1", "uniprot_id": "UBX1_YEAST", "mass": 46987.0, "length": 423, "protein_name": "UBX domain-containing protein 1", "gene_name": "SHP1", "organism": "Yeast", "refseq_name": "protein phosphatase regulator SHP1", "refseq_ac": "NP_009495", "gene_names_uniprotkb": "SHP1; UBX1; YBL0509; YBL0515", "gene_names_refseq": "SHP1; UBX1", "protein_names_uniprotkb": "UBX domain-containing protein 1; Suppressor of high-copy PP1 protein", "protein_names_refseq": "protein phosphatase regulator SHP1", "tax_id": 559292, "disease": "", "pathway": " (sce:YBL058W)", "pathway_count": 1, "publication_count": 30, "publication_id_list": "11875433;14562095;14562106;15258615;15665377;16427015;17322287;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20489023;20702584;21126336;21177495;22106047;22218487;23749301;24374639;24909858;30516470;32597660;33481703;33491328;7813418;7891699;8154187", "class_list": "", "function": "Involved in CDC48-dependent protein degradation through the ubiquitin/proteasome pathway. Direct or indirect positive regulator of GLC7 activity., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 34, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VPU2;E9P8S9", "ec_number_list": "", "go_molecular_function": "GO:0036435 K48-linked polyubiquitin modification-dependent protein binding;GO:0019888 protein phosphatase regulator activity;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0031468 nuclear membrane reassembly;GO:0043335 protein unfolding;GO:0000045 autophagosome assembly;GO:0005977 glycogen metabolic process;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 3.1, "record_id": "P34223-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P34730-1", "uniprot_id": "BMH2_YEAST", "mass": 31061.0, "length": 273, "protein_name": "Protein BMH2", "gene_name": "BMH2", "organism": "Yeast", "refseq_name": "14-3-3 family protein BMH2", "refseq_ac": "NP_010384", "gene_names_uniprotkb": "BMH2; YD8557.08", "gene_names_refseq": "BMH2; SCD3", "protein_names_uniprotkb": "Protein BMH2", "protein_names_refseq": "14-3-3 family protein BMH2", "tax_id": 559292, "disease": "Miller-Dieker lissencephaly syndrome (Disease Ontology:DOID:0060469); left ventricular noncompaction (Disease Ontology:DOID:0060480)", "pathway": " (sce:YDR099W); (R-SCE-3371453); (R-SCE-3371511); (R-SCE-5625740); (R-SCE-75035)", "pathway_count": 5, "publication_count": 16, "publication_id_list": "12551942;14562095;14562106;17244705;17351133;18407956;21126336;22320399;24374639;24909858;33481703;33491328;7744048;8524799;9169867;9298649", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A2TBP2;D6VS86;Q06HN5", "ec_number_list": "", "go_molecular_function": "GO:0003688 DNA replication origin binding;GO:0050815 phosphoserine residue binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication;GO:0000278 mitotic cell cycle;GO:0007165 signal transduction;GO:0043066 negative regulation of apoptotic process;GO:0007265 Ras protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P34730-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P35169-1", "uniprot_id": "TOR1_YEAST", "mass": 281140.0, "length": 2470, "protein_name": "Serine/threonine-protein kinase TOR1", "gene_name": "TOR1", "organism": "Yeast", "refseq_name": "phosphatidylinositol kinase-related protein kinase TOR1", "refseq_ac": "NP_012600", "gene_names_uniprotkb": "TOR1; DRR1; J1803", "gene_names_refseq": "DRR1; TOR1", "protein_names_uniprotkb": "Serine/threonine-protein kinase TOR1; 2.7.11.1; Dominant rapamycin resistance protein 1; Phosphatidylinositol kinase homolog TOR1; Target of rapamycin kinase 1", "protein_names_refseq": "phosphatidylinositol kinase-related protein kinase TOR1", "tax_id": 559292, "disease": "alcohol-associated liver disease (Disease Ontology:DOID:0070658); polycystic kidney disease (Disease Ontology:DOID:0080322); autosomal recessive polycystic kidney disease (Disease Ontology:DOID:0110861); prostate cancer (Disease Ontology:DOID:10283); portal hypertension (Disease Ontology:DOID:10762); hypertension (Disease Ontology:DOID:10763); sciatic neuropathy (Disease Ontology:DOID:11446); crescentic glomerulonephritis (Disease Ontology:DOID:13139); interstitial cystitis (Disease Ontology:DOID:13949); cancer (Disease Ontology:DOID:162); pancreatic cancer (Disease Ontology:DOID:1793); status epilepticus (Disease Ontology:DOID:1824); colon cancer (Disease Ontology:DOID:219); transient cerebral ischemia (Disease Ontology:DOID:224); idiopathic interstitial pneumonia (Disease Ontology:DOID:2797); acute kidney failure (Disease Ontology:DOID:3021); high grade glioma (Disease Ontology:DOID:3070); temporal lobe epilepsy (Disease Ontology:DOID:3328); chondrosarcoma (Disease Ontology:DOID:3371); middle cerebral artery infarction (Disease Ontology:DOID:3525); renal cell carcinoma (Disease Ontology:DOID:4450); ureteral obstruction (Disease Ontology:DOID:5199); lung small cell carcinoma (Disease Ontology:DOID:5409); schizophrenia (Disease Ontology:DOID:5419); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); pulmonary hypertension (Disease Ontology:DOID:6432); hepatocellular carcinoma (Disease Ontology:DOID:684); muscular atrophy (Disease Ontology:DOID:767); end stage renal disease (Disease Ontology:DOID:783); kidney angiomyolipoma (Disease Ontology:DOID:8411); vascular dementia (Disease Ontology:DOID:8725); autosomal dominant polycystic kidney disease (Disease Ontology:DOID:898); type 2 diabetes mellitus (Disease Ontology:DOID:9352); obesity (Disease Ontology:DOID:9970)", "pathway": " (sce:YJR066W)", "pathway_count": 1, "publication_count": 32, "publication_id_list": "10198052;10329624;10436010;10604478;10973982;10995454;11741537;12408816;12631735;14562106;15620355;15772072;17560372;23749301;24374639;25767889;28483912;28993463;29698392;32801125;33491328;34535752;36691768;7606777;8186460;8413204;8641269;8654975;8741837;8840504;9539725;9843498", "class_list": "", "function": "Phosphatidylinositol 3-kinase homolog, component of TORC1, which regulates multiple cellular processes to control cell growth in response to environmental signals. Nutrient limitation and environmental stress signals cause inactivation of TORC1. Active TORC1 positively controls ribosome biogenesis via control of rRNA, ribosomal protein and tRNA gene expression, and rRNA processing. TORC1 positively controls protein biosynthesis by regulation of mRNA stability, translation initiation factor activity, and high-affinity amino acid permeases that serve to provide amino acids for use by the translation machinery. TORC1 also promotes growth by sequestering a number of nutrient and general stress-responsive transcription factors in the cytoplasm. TORC1 negatively controls macroautophagy, a process to recycle surplus cytoplasmic mass under nutrient starvation conditions. TORC1 controls many of these processes via TIP41-TAP42-mediated inhibition of the type 2A-related phosphatases PP2A and SIT4 (PubMed:10198052, PubMed:10329624, PubMed:10604478, PubMed:10995454, PubMed:11741537, PubMed:15620355, PubMed:28993463, PubMed:7606777, PubMed:8741837, PubMed:9539725, PubMed:9843498). In nutrient-rich conditions, responsible for the phosphorylation of AGC S6 kinase (S6K) YPK3, activating YPK3 kinase activity and promoting phosphorylation of ribosomal protein S6 (PubMed:25767889). Phosphorylates kinase SCH9 at 6 amino acids in the C-terminus, activating SCH9 kinase activity to properly regulate ribosome biogenesis, translation initiation, and entry into stationary phase (PubMed:17560372). Activates dormant ribosomes by mediating phosphorylation of STM1, leading to STM1 inactivation and reactivation of translation (PubMed:36691768)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 9, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 35, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VWN7", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0044877 protein-containing complex binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0007584 response to nutrient;GO:0034605 cellular response to heat;GO:0006974 DNA damage response;GO:0042254 ribosome biogenesis;GO:0001558 regulation of cell growth", "synthesized_glycan_count": 0, "hit_score": 3.3, "record_id": "P35169-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P35180-1", "uniprot_id": "TOM20_YEAST", "mass": 20317.0, "length": 183, "protein_name": "Mitochondrial import receptor subunit TOM20", "gene_name": "TOM20", "organism": "Yeast", "refseq_name": "TOM complex receptor protein TOM20", "refseq_ac": "NP_011596", "gene_names_uniprotkb": "TOM20; MAS20; MOM19", "gene_names_refseq": "MAS20; MOM19; TOM20", "protein_names_uniprotkb": "Mitochondrial import receptor subunit TOM20; Mitochondrial 20 kDa outer membrane protein; Protein MAS20; Translocase of outer membrane 20 kDa subunit", "protein_names_refseq": "TOM complex receptor protein TOM20", "tax_id": 559292, "disease": "cancer (Disease Ontology:DOID:162); muscular atrophy (Disease Ontology:DOID:767)", "pathway": " (sce:YGR082W); (R-SCE-5205685)", "pathway_count": 2, "publication_count": 17, "publication_id_list": "10519552;14562106;17322287;18407956;19795423;19823750;21126336;21215441;22218487;23749301;24374639;33481703;33491328;8132642;8223428;9169869;9774667", "class_list": "", "function": "Central component of the TOM (translocase of outer membrane) receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUL4", "ec_number_list": "", "go_molecular_function": "GO:0030943 mitochondrion targeting sequence binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0005742 mitochondrial outer membrane translocase complex", "go_biological_process": "GO:0045040 protein insertion into mitochondrial outer membrane;GO:0006886 intracellular protein transport;GO:0030150 protein import into mitochondrial matrix;GO:0016031 tRNA import into mitochondrion", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P35180-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P35187-1", "uniprot_id": "SGS1_YEAST", "mass": 163837.0, "length": 1447, "protein_name": "ATP-dependent helicase SGS1", "gene_name": "SGS1", "organism": "Yeast", "refseq_name": "ATP-dependent DNA helicase SGS1", "refseq_ac": "NP_013915", "gene_names_uniprotkb": "SGS1; TPS1; YM9646.02C", "gene_names_refseq": "SGS1", "protein_names_uniprotkb": "ATP-dependent helicase SGS1; 5.6.2.4; DNA 3'-5' helicase Sgs1; Helicase TPS1", "protein_names_refseq": "ATP-dependent DNA helicase SGS1", "tax_id": 559292, "disease": "Bloom syndrome (Disease Ontology:DOID:2717); Werner syndrome (Disease Ontology:DOID:5688)", "pathway": " (sce:YMR190C)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "10198430;10640278;10647186;12200140;12228808;15889139;15899853;19779198;22820947;23749301;24374639;32597660;33481703;33491328;33764556;7736577;7969174;8878475;9169872;9545297", "class_list": "", "function": "ATP-dependent 3'-5' DNA helicase able to unwind duplex DNA or DNA:RNA heteroduplex (PubMed:8878475, PubMed:9545297). Unwinds G-quadruplex DNA; unwinding occurs in the 3'-5' direction, requires a 3' single-stranded end of at least 7 nucleotides (PubMed:10198430). Helicase activity is higher on G-quadruplex substrates than on duplex DNA substrates (PubMed:10198430). Assayed with a catalytic fragment (residues 400-1268) (PubMed:10198430). Telomeres and rDNA are notably G-rich; formation of G-quadruplex DNA would block DNA replication and transcription (PubMed:10198430). Acts as an integral component of the S-phase checkpoint response, which arrests cells due to DNA damage or blocked fork progression during DNA replication (PubMed:10640278). Can create a deleterious topological substrate that TOP3 preferentially resolves. The TOP3-SGS1 protein complex may function as a eukaryotic reverse gyrase introducing positive supercoils into extrachromosomal ribosomal DNA rings (PubMed:7969174). Together with topoisomerase II has a role in chromosomal segregation (PubMed:7736577). Maintains rDNA structure where it has a role in re-starting stalled replication forks (PubMed:12228808)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 27, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W014", "ec_number_list": "3.6.4.13;5.6.2.3;3.6.4.10;3.6.-.-;5.6.2.4;3.6.4.-;5.6.1.4;3.6.4.12;3.6.4.6;5.6.2.5;3.6.1.-;2.3.2.27;3.1.-.-;3.4.24.-;3.6.5.-;2.7.4.3;2.7.11.1;7.2.2.-", "go_molecular_function": "GO:0043138 3'-5' DNA helicase activity;GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003678 DNA helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005694 chromosome;GO:0031422 RecQ family helicase-topoisomerase III complex", "go_biological_process": "GO:0006281 DNA repair;GO:0000723 telomere maintenance;GO:0006260 DNA replication;GO:0000724 double-strand break repair via homologous recombination;GO:0031573 mitotic intra-S DNA damage checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P35187-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P35189-1", "uniprot_id": "TAF14_YEAST", "mass": 27440.0, "length": 244, "protein_name": "Transcription initiation factor TFIID subunit 14", "gene_name": "TAF14", "organism": "Yeast", "refseq_name": "TATA-binding protein-associated factor TAF14", "refseq_ac": "NP_015196", "gene_names_uniprotkb": "TAF14; ANC1; CST10; SWP29; TAF30; TFG3", "gene_names_refseq": "ANC1; SWP29; TAF14; TAF30; TFG3", "protein_names_uniprotkb": "Transcription initiation factor TFIID subunit 14; Actin non-complementing mutant 1; Chromosome stability protein 10; SWI/SNF chromatin-remodeling complex subunit TAF14; SWI/SNF complex 29 kDa subunit; SWI/SNF complex subunit TAF14; TBP-associated factor 14; TBP-associated factor 30 kDa; Transcription factor G 30 kDa subunit; Transcription initiation factor TFIIF 30 kDa subunit", "protein_names_refseq": "TATA-binding protein-associated factor TAF14", "tax_id": 559292, "disease": "familial adult myoclonic epilepsy 4 (Disease Ontology:DOID:0111693)", "pathway": " (sce:YPL129W)", "pathway_count": 1, "publication_count": 26, "publication_id_list": "10788514;10817755;12093743;12138208;12516863;12524530;12672490;12887900;1331085;14562106;17157260;22106047;23749301;24374639;25104842;26341557;27089029;30385749;32597660;33481703;33491328;7949419;7995524;8423796;9169875;9618449", "class_list": "", "function": "Functions as a component of the DNA-binding general transcription factor complex TFIID, the RNA polymerase II associated general transcription factor complex TFIIF, and the chromatin-remodeling complex SWI/SNF (PubMed:10788514, PubMed:12138208, PubMed:12516863, PubMed:9618449). Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation (PubMed:10788514, PubMed:12138208, PubMed:12516863, PubMed:9618449). TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription (PubMed:10788514, PubMed:12138208, PubMed:12516863, PubMed:9618449). TFIIF is essential for the initiation of transcription by RNA polymerase II (PubMed:10788514, PubMed:12138208, PubMed:12516863, PubMed:9618449). TFIIF functions include the recruitment of RNA polymerase II to the promoter bound DNA-TBP-TFIIB complex, decreasing the affinity of RNA polymerase II for non-specific DNA, allowing for the subsequent recruitment of TFIIE and TFIIH, and facilitating RNA polymerase II elongation (PubMed:10788514, PubMed:12138208, PubMed:12516863, PubMed:30385749, PubMed:9618449). TAF14 acts as a chromatin reader that specifically recognizes and binds histones that are acylated (PubMed:26341557, PubMed:27089029). Recognizes and binds histone H3 acetylated or crotonylated at 'Lys-9' (H3K9ac and H3K9cr, respectively), with some preference for crotonylated lysine (PubMed:26341557, PubMed:27089029, PubMed:30385749). Component of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, is required for the positive and negative regulation of gene expression of a large number of genes (PubMed:12672490). It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors (PubMed:12672490). Component of the NuA3 histone acetyltransferase complex (PubMed:17157260). The NuA3 HAT complex has 2 functionally distinct forms. NuA3a binds H3K4me3, through the PHD finger of YNG1, and acetylates H3K14 at the promoter region of actively transcribed genes to promote transcription initiation. NuA3b binds H3K36me3 at the coding regions of actively transcribed genes, through the PWWP domain of PDP3, and coordinates transcription elongation (PubMed:25104842). Does not bind DNA (PubMed:30385749)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3N8;Q02460", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0042393 histone binding;GO:0016251 RNA polymerase II general transcription initiation factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016514 SWI/SNF complex;GO:0031011 Ino80 complex;GO:0000785 chromatin;GO:0005669 transcription factor TFIID complex", "go_biological_process": "GO:0006281 DNA repair;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 2.7, "record_id": "P35189-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P35193-1", "uniprot_id": "ATG19_YEAST", "mass": 47599.0, "length": 415, "protein_name": "Autophagy-related protein 19", "gene_name": "ATG19", "organism": "Yeast", "refseq_name": "Atg19p", "refseq_ac": "NP_014559", "gene_names_uniprotkb": "ATG19; CVT19; O0980; YOL01", "gene_names_refseq": "ATG19; CVT19", "protein_names_uniprotkb": "Autophagy-related protein 19; Cytoplasm-to-vacuole targeting protein 19", "protein_names_refseq": "Atg19p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL082W)", "pathway_count": 1, "publication_count": 46, "publication_id_list": "11382752;11430817;11675395;12446664;12479807;12479808;14536056;14562095;14562106;15138258;15194695;15659643;15665377;15801807;16186126;17132049;17192412;17238920;17287358;17322287;17563356;17700056;18407956;18497569;19021777;19061865;19398890;19779198;20489023;20659891;20702584;21126336;21177495;21228276;21343297;22123825;23749301;24374639;25287303;32597660;33481703;33491328;35363116;7900427;8533473;9169874", "class_list": "", "function": "Cargo-receptor protein involved in the cytoplasm to vacuole transport (Cvt) and in autophagy. Recognizes cargo proteins, such as APE4, LAP3, LAP4 and AMS1 and delivers them to the pre-autophagosomal structure for eventual engulfment by the autophagosome and targeting to the vacuole. Involved in the organization of the preautophagosomal structure (PAS). ATG19 association with cargo protein is required to localize ATG11 to the PAS. Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates, and is essential for the survival of cells subjected to severe ER stress. Also plays a role in regulation of filamentous growth., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 16, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1Y6;Q6B1A6", "ec_number_list": "", "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0034045 phagophore assembly site membrane;GO:0000407 phagophore assembly site;GO:0034270 Cvt complex", "go_biological_process": "GO:0015031 protein transport;GO:0006914 autophagy;GO:0016050 vesicle organization;GO:0036503 ERAD pathway;GO:0031503 protein-containing complex localization", "synthesized_glycan_count": 0, "hit_score": 4.7, "record_id": "P35193-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P35207-1", "uniprot_id": "SKI2_YEAST", "mass": 146059.0, "length": 1287, "protein_name": "Antiviral helicase SKI2", "gene_name": "SKI2", "organism": "Yeast", "refseq_name": "SKI complex RNA helicase subunit SKI2", "refseq_ac": "NP_013502", "gene_names_uniprotkb": "SKI2; L8084.17", "gene_names_refseq": "SKI2", "protein_names_uniprotkb": "Antiviral helicase SKI2; 3.6.4.13; Superkiller protein 2", "protein_names_refseq": "SKI complex RNA helicase subunit SKI2", "tax_id": 559292, "disease": "trichohepatoenteric syndrome 2 (Disease Ontology:DOID:0111416)", "pathway": " (sce:YLR398C); (R-SCE-429958)", "pathway_count": 2, "publication_count": 28, "publication_id_list": "10611222;10744028;10922069;11532933;11720286;12769863;14562095;14562106;14671320;15044803;17330950;17563356;18407956;19779198;21177495;23749301;24374639;32597660;33481703;33491328;363683;6371496;7739552;7739557;7816623;8321235;9169871;9482746", "class_list": "", "function": "RNA helicase component of the SKI complex involved in 3'-mRNA degradation pathway. Represses dsRNA virus propagation by specifically blocking translation of viral mRNAs, perhaps recognizing the absence of CAP or poly(A). Essential for cell growth only in the presence of M1 replicon., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ33;Q06047", "ec_number_list": "3.6.4.13;5.6.2.3;3.6.4.10;3.6.-.-;5.6.2.4;3.6.4.-;5.6.1.4;3.6.4.12;3.6.4.6;5.6.2.5;3.6.5.-;3.6.1.-;2.3.2.27;3.1.-.-;3.4.24.-;3.1.13.-;3.1.26.-;2.7.4.3;2.7.11.1;7.2.2.-", "go_molecular_function": "GO:0003677 DNA binding;GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:0055087 Ski complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay;GO:0070481 nuclear-transcribed mRNA catabolic process, non-stop decay;GO:0006417 regulation of translation;GO:0051607 defense response to virus;GO:0006402 mRNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 2.9, "record_id": "P35207-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P35734-1", "uniprot_id": "ASK1_YEAST", "mass": 32072.0, "length": 292, "protein_name": "DASH complex subunit ASK1", "gene_name": "ASK1", "organism": "Yeast", "refseq_name": "Ask1p", "refseq_ac": "NP_012872", "gene_names_uniprotkb": "ASK1; YKL306", "gene_names_refseq": "ASK1", "protein_names_uniprotkb": "DASH complex subunit ASK1; Associated with spindles and kinetochores protein 1; Outer kinetochore protein ASK1", "protein_names_refseq": "Ask1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YKL052C)", "pathway_count": 1, "publication_count": 40, "publication_id_list": "11782438;11799062;12408861;12695666;12925767;14562095;14562106;15640796;15664196;16415853;16715078;16777964;17322287;17330950;17460120;17563356;17620411;17643123;18079178;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22218487;23749301;24374639;24909858;24930965;25236177;32597660;32946748;33481703;33491328;36701236;8091862;8196765", "class_list": "", "function": "Component of the DASH complex that connects microtubules with kinetochores and couples microtubule depolymerization to chromosome movement; it is involved in retrieving kinetochores to the spindle poles before their re-orientation on the spindle in early mitosis and allows microtubule depolymerization to pull chromosomes apart and resist detachment during anaphase (PubMed:15664196, PubMed:16415853, PubMed:16777964, PubMed:17460120, PubMed:17643123, PubMed:18079178). Kinetochores, consisting of a centromere-associated inner segment and a microtubule-contacting outer segment, play a crucial role in chromosome segregation by mediating the physical connection between centromeric DNA and microtubules (PubMed:11782438). Kinetochores also serve as an input point for the spindle assembly checkpoint, which delays anaphase until all chromosomes have bioriented on the mitotic spindle (PubMed:11782438, PubMed:12408861). During spindle-kinetochore attachment, kinetochores first attach to the lateral surface of spindle microtubules, which supports the congression of chromosomes toward the middle of the dividing cell; they then slide along towards the spindle pole, a process independent of the DASH complex but requiring the NDC80 complex (PubMed:17620411). When the end of a disassembling microtubule reaches the laterally attached kinetochore, the DASH complex together with the NDC80 complex and STU2 convert lateral attachment to end-on capture to produce a structure that can track with microtubule shortening and sustain attachment when tension is applied across sister kinetochores upon their biorientation (PubMed:15640796, PubMed:15664196, PubMed:17620411, PubMed:18079178, PubMed:25236177). Microtubule depolymerization proceeds by protofilament splaying and induces the kinetochore-attached DASH complex to slide longitudinally, thereby helping to transduce depolymerization energy into pulling forces to disjoin chromatids (PubMed:16415853, PubMed:16777964, PubMed:17620411). Incorrect microtubule attachments are corrected by releasing microubules from the kinetochore through phosphorylation by IPL1 of kinetochore components (PubMed:12408861). Links the microtubule cytoskeleton to chromosomes during interphase (PubMed:36701236). Also contributes to the poleward transport of kinetochores on microtubules following centromeric DNA replication in S-phase (PubMed:18079178)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 26, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VXN5;Q68EC3;Q6B290", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005874 microtubule;GO:0072686 mitotic spindle;GO:0042729 DASH complex;GO:0044732 mitotic spindle pole body", "go_biological_process": "GO:0051301 cell division;GO:0031116 positive regulation of microtubule polymerization;GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore;GO:1990758 mitotic sister chromatid biorientation;GO:1990976 protein transport along microtubule to mitotic spindle pole body", "synthesized_glycan_count": 0, "hit_score": 4.1, "record_id": "P35734-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P36000-1", "uniprot_id": "AP1B1_YEAST", "mass": 81869.0, "length": 726, "protein_name": "AP-1 complex subunit beta-1", "gene_name": "APL2", "organism": "Yeast", "refseq_name": "Apl2p", "refseq_ac": "NP_012787", "gene_names_uniprotkb": "APL2", "gene_names_refseq": "APL2", "protein_names_uniprotkb": "AP-1 complex subunit beta-1; Beta-1-adaptin; Clathrin assembly protein complex 1 beta-1 large chain; Clathrin assembly protein large beta-1 chain", "protein_names_refseq": "Apl2p", "tax_id": 559292, "disease": "Kartagener syndrome (Disease Ontology:DOID:0050144); visceral heterotaxy (Disease Ontology:DOID:0050545); middle cerebral artery infarction (Disease Ontology:DOID:3525); primary ciliary dyskinesia (Disease Ontology:DOID:9562)", "pathway": " (sce:YKL135C); (R-SCE-432720); (R-SCE-437239); (R-SCE-8856825); (R-SCE-8856828); (R-SCE-8866427); (R-SCE-8964038)", "pathway_count": 7, "publication_count": 8, "publication_id_list": "10564262;14562106;18407956;24374639;33481703;33491328;7615679;8196765", "class_list": "", "function": "Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. The AP-1 complex interacts directly with clathrin., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VX61", "ec_number_list": "", "go_molecular_function": "GO:0030276 clathrin binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005905 clathrin-coated pit;GO:0030121 AP-1 adaptor complex", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0016192 vesicle-mediated transport;GO:0048203 vesicle targeting, trans-Golgi to endosome;GO:0006896 Golgi to vacuole transport", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P36000-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P36003-1", "uniprot_id": "NNK1_YEAST", "mass": 103956.0, "length": 928, "protein_name": "Nitrogen network kinase 1", "gene_name": "NNK1", "organism": "Yeast", "refseq_name": "protein kinase NNK1", "refseq_ac": "NP_012750", "gene_names_uniprotkb": "NNK1; YKL635", "gene_names_refseq": "NNK1", "protein_names_uniprotkb": "Nitrogen network kinase 1; 2.7.11.1", "protein_names_refseq": "protein kinase NNK1", "tax_id": 559292, "disease": "", "pathway": " (sce:YKL171W)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "11914276;17557329;17563356;18407956;19779198;19795423;19823750;20489023;23749301;24374639;27821475;32597660;33481703;33491328;8091858;8196765", "class_list": "", "function": "Serine/threonine-protein kinase involved in the phosphorylation of the NAD(+)-dependent glutamate dehydrogenase GDH2. When overexpressed, confers hypersensitivity to rapamycin and induces rapid nuclear accumulation of GLN3 to activate the transcription of nitrogen-regulated genes., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 46, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VX29", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0009931 calcium-dependent protein serine/threonine kinase activity;GO:0004672 protein kinase activity;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0004683 calcium/calmodulin-dependent protein kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006508 proteolysis;GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P36003-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P36024-1", "uniprot_id": "SIS2_YEAST", "mass": 62478.0, "length": 562, "protein_name": "Phosphopantothenoylcysteine decarboxylase subunit SIS2", "gene_name": "SIS2", "organism": "Yeast", "refseq_name": "phosphopantothenoylcysteine decarboxylase complex subunit SIS2", "refseq_ac": "NP_012998", "gene_names_uniprotkb": "SIS2; HAL3", "gene_names_refseq": "HAL3; SIS2", "protein_names_uniprotkb": "Phosphopantothenoylcysteine decarboxylase subunit SIS2; Halotolerance protein HAL3; Sit4 suppressor 2", "protein_names_refseq": "phosphopantothenoylcysteine decarboxylase complex subunit SIS2", "tax_id": 559292, "disease": "neurodegeneration with brain iron accumulation (Disease Ontology:DOID:0110734); dilated cardiomyopathy (Disease Ontology:DOID:12930)", "pathway": " (sce:YKR072C)", "pathway_count": 1, "publication_count": 28, "publication_id_list": "14562106;14690591;15665377;17330950;17563356;18407956;19684113;19779198;19795423;19823750;19915539;20489023;20702584;21126336;21177495;22218487;22814378;23749301;24374639;30516470;32597660;33481703;33491328;34965436;7565698;7705654;8196765;9636153", "class_list": "", "function": "Component of the phosphopantothenoylcysteine decarboxylase (PPCDC) involved in the coenzyme A synthesis. Acts as an inhibitory subunit of protein phosphatase PPZ1, which is involved in many cellular processes such as G1-S transition or salt tolerance. Also modulates the expression of the ENA1 ATPase., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 30, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VXD3", "ec_number_list": "", "go_molecular_function": "GO:0004865 protein serine/threonine phosphatase inhibitor activity;GO:0042802 identical protein binding;GO:0003824 catalytic activity;GO:0010181 FMN binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0071513 phosphopantothenoylcysteine decarboxylase complex;GO:1990143 CoA-synthesizing protein complex", "go_biological_process": "GO:0007346 regulation of mitotic cell cycle;GO:0009651 response to salt stress;GO:0015937 coenzyme A biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 2.9, "record_id": "P36024-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P36027-1", "uniprot_id": "MID2_YEAST", "mass": 39146.0, "length": 376, "protein_name": "Cell wall integrity sensor MID2", "gene_name": "MID2", "organism": "Yeast", "refseq_name": "Mid2p", "refseq_ac": "NP_013436", "gene_names_uniprotkb": "MID2; KAI1; L8543.19; SMS1", "gene_names_refseq": "KAI1; MID2", "protein_names_uniprotkb": "Cell wall integrity sensor MID2; Mating pheromone-induced death protein 2; Protein kinase A interference protein 1; Serine-rich multicopy suppressor protein 1", "protein_names_refseq": "Mid2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR332W)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "10330137;10348843;11113201;12949174;13679573;14562095;16087742;18410496;19779198;20702584;22218487;23749301;24374639;32597660;33481703;33491328;7828875;7999801;8355657;9169871", "class_list": "", "function": "Cell wall stress sensor. Involved in activation of a response that includes both stress-related increased chitin synthesis and the MPK1 mitogen-activated protein kinase cell integrity pathway. High-copy activator of the SKN7 transcription factor. Required during induction of MPK1 tyrosine phosphorylation under a variety of stress conditions. Required for PKC pathway activation under low pH conditions. Required for cell integrity signaling during pheromone-induced morphogenesis. Activates ROM1 or ROM2 catalyzed guanine nucleotide exchange toward RHO1 in cell wall integrity signaling., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 1, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 1, "mined_n_glycosites": 1, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "D6VYX3;P41944", "ec_number_list": "", "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0000324 fungal-type vacuole;GO:0043332 mating projection tip", "go_biological_process": "GO:0006970 response to osmotic stress;GO:0036498 IRE1-mediated unfolded protein response;GO:0010447 response to acidic pH;GO:0000425 pexophagy;GO:0031505 fungal-type cell wall organization", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P36027-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P36046-1", "uniprot_id": "MIA40_YEAST", "mass": 44536.0, "length": 403, "protein_name": "Mitochondrial intermembrane space import and assembly protein 40", "gene_name": "MIA40", "organism": "Yeast", "refseq_name": "Mia40p", "refseq_ac": "NP_012726", "gene_names_uniprotkb": "MIA40; TIM40", "gene_names_refseq": "FMP15; MIA40; TIM40", "protein_names_uniprotkb": "Mitochondrial intermembrane space import and assembly protein 40; Mitochondrial import inner membrane translocase TIM40", "protein_names_refseq": "Mia40p", "tax_id": 559292, "disease": "mitochondrial complex I deficiency (Disease Ontology:DOID:0060536)", "pathway": " (sce:YKL195W)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "12748633;14562095;14562106;14576278;14690591;15359280;15364952;15620710;15989955;16181637;16407407;18407956;19667201;21126336;21944719;24374639;32597660;33481703;33491328;8196765", "class_list": "", "function": "Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Forms a redox cycle with ERV1 that involves a disulfide relay system. Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond and is able to undergo folding in the IMS. Reduced MIA40 is reoxidized by FAD-linked sulfhydryl oxidase ERV1., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VX05", "ec_number_list": "", "go_molecular_function": "GO:0051537 2 iron, 2 sulfur cluster binding;GO:0016491 oxidoreductase activity;GO:0015035 protein-disulfide reductase activity;GO:0003756 protein disulfide isomerase activity;GO:0016972 thiol oxidase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005758 mitochondrial intermembrane space", "go_biological_process": "GO:0045041 protein import into mitochondrial intermembrane space;GO:0006457 protein folding;GO:0051604 protein maturation", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P36046-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P36076-1", "uniprot_id": "CAB3_YEAST", "mass": 65238.0, "length": 571, "protein_name": "Coenzyme A biosynthesis protein 3", "gene_name": "CAB3", "organism": "Yeast", "refseq_name": "phosphopantothenoylcysteine decarboxylase complex subunit CAB3", "refseq_ac": "NP_012835", "gene_names_uniprotkb": "CAB3", "gene_names_refseq": "CAB3", "protein_names_uniprotkb": "Coenzyme A biosynthesis protein 3", "protein_names_refseq": "phosphopantothenoylcysteine decarboxylase complex subunit CAB3", "tax_id": 559292, "disease": "neurodegeneration with brain iron accumulation (Disease Ontology:DOID:0110734); dilated cardiomyopathy (Disease Ontology:DOID:12930)", "pathway": " (sce:YKL088W); (R-SCE-196783)", "pathway_count": 2, "publication_count": 24, "publication_id_list": "14562095;14562106;14690591;15665377;17287358;17330950;17563356;18407956;19266201;19779198;19795423;19823750;19915539;20702584;21177495;22218487;23749301;24374639;24909858;30516470;32597660;33481703;33491328;8196765", "class_list": "", "function": "Component of the phosphopantothenoylcysteine decarboxylase (PPCDC) involved in the coenzyme A synthesis., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 27, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXK0", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0003824 catalytic activity;GO:0010181 FMN binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0071513 phosphopantothenoylcysteine decarboxylase complex;GO:1990143 CoA-synthesizing protein complex", "go_biological_process": "GO:0015937 coenzyme A biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "P36076-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P36123-1", "uniprot_id": "SA190_YEAST", "mass": 117098.0, "length": 1033, "protein_name": "SIT4-associating protein SAP190", "gene_name": "SAP190", "organism": "Yeast", "refseq_name": "Sap190p", "refseq_ac": "NP_012953", "gene_names_uniprotkb": "SAP190", "gene_names_refseq": "SAP190", "protein_names_uniprotkb": "SIT4-associating protein SAP190", "protein_names_refseq": "Sap190p", "tax_id": 559292, "disease": "", "pathway": " (sce:YKR028W); (R-SCE-204005)", "pathway_count": 2, "publication_count": 21, "publication_id_list": "14718557;15367655;15665377;17330950;17563356;18407956;19779198;19795423;19823750;20702584;21126336;21177495;23749301;24374639;30516470;32597660;33229814;33481703;33491328;8196765;8649382", "class_list": "", "function": "Positive regulator of protein phosphatase SIT4. Involved in the general amino acid control (GAAC) response regulated by TOR. Involved in the dephosphorylation of the elongator complex subunit IKI3., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 39, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VX93", "ec_number_list": "", "go_molecular_function": "GO:0019888 protein phosphatase regulator activity;GO:0019903 protein phosphatase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0000082 G1/S transition of mitotic cell cycle;GO:0009966 regulation of signal transduction;GO:0031929 TOR signaling;GO:0002098 tRNA wobble uridine modification", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "P36123-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P36160-1", "uniprot_id": "RPF2_YEAST", "mass": 39599.0, "length": 344, "protein_name": "Ribosome biogenesis protein RPF2", "gene_name": "RPF2", "organism": "Yeast", "refseq_name": "rRNA-binding ribosome biosynthesis protein RPF2", "refseq_ac": "NP_013007", "gene_names_uniprotkb": "RPF2; YKR401", "gene_names_refseq": "RPF2", "protein_names_uniprotkb": "Ribosome biogenesis protein RPF2", "protein_names_refseq": "rRNA-binding ribosome biosynthesis protein RPF2", "tax_id": 559292, "disease": "", "pathway": " (sce:YKR081C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "12702244;14562106;17330950;24374639;33491328;37291423;8196765;8203164", "class_list": "", "function": "Required for biogenesis of the 60S ribosomal subunit., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VXE1", "ec_number_list": "", "go_molecular_function": "GO:0019843 rRNA binding;GO:0008097 5S rRNA binding;GO:0008312 7S RNA binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0030687 preribosome, large subunit precursor", "go_biological_process": "GO:0000027 ribosomal large subunit assembly;GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:1902626 assembly of large subunit precursor of preribosome", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P36160-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P36517-1", "uniprot_id": "RM04_YEAST", "mass": 36965.0, "length": 319, "protein_name": "Large ribosomal subunit protein uL29m", "gene_name": "MRPL4", "organism": "Yeast", "refseq_name": "mitochondrial 54S ribosomal protein uL29m MRPL4", "refseq_ac": "NP_013544", "gene_names_uniprotkb": "MRPL4; L9753.1", "gene_names_refseq": "MRPL4; uL29m", "protein_names_uniprotkb": "Large ribosomal subunit protein uL29m; 54S ribosomal protein L4, mitochondrial; YmL4", "protein_names_refseq": "mitochondrial 54S ribosomal protein uL29m MRPL4", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR439W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562095;14562106;14576278;24374639;24675956;25609543;3060376;33491328;7828914;9169871", "class_list": "", "function": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ74", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:1902775 mitochondrial large ribosomal subunit assembly;GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P36517-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38074-1", "uniprot_id": "ANM1_YEAST", "mass": 39786.0, "length": 348, "protein_name": "Protein arginine N-methyltransferase 1", "gene_name": "HMT1", "organism": "Yeast", "refseq_name": "protein-arginine omega-N methyltransferase HMT1", "refseq_ac": "NP_009590", "gene_names_uniprotkb": "HMT1; ODP1; RMT1; YBR0320", "gene_names_refseq": "HCP1; HMT1; ODP1; RMT1", "protein_names_uniprotkb": "Protein arginine N-methyltransferase 1; 2.1.1.319; Major type I protein arginine N-methyltransferase; Type I PRMT; hnRNP arginine N-methyltransferase", "protein_names_refseq": "protein-arginine omega-N methyltransferase HMT1", "tax_id": 559292, "disease": "asthma (Disease Ontology:DOID:2841); cleft palate (Disease Ontology:DOID:674)", "pathway": " (sce:YBR034C); (R-SCE-3214858); (R-SCE-8876725); (R-SCE-9018519)", "pathway_count": 4, "publication_count": 22, "publication_id_list": "10652296;11101900;11779864;12097318;12756332;14562106;15314027;17158743;17322287;20035717;20053728;20823272;22997150;24374639;29183786;33491328;7813418;7896706;8091864;8647869;8668183;9499403", "class_list": "", "function": "S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that catalyzes both the mono- and asymmetric (type I) dimethylation of the guanidino nitrogens of arginine residues in a variety of RNA-binding proteins such as heterogeneous nuclear ribonucleoproteins (hnRNPs) and small nuclear ribonucleoproteins (snRNPs) (PubMed:8647869, PubMed:8668183). Methylates NAB2, NPL3, HRP1 and YRA1, shuttling hnRNPs involved in mRNA processing and export, facilitating their export out of the nucleus (PubMed:10652296, PubMed:11779864, PubMed:15314027, PubMed:8668183, PubMed:9499403). Methylation of NPL3 weakens its interaction with THO2, a component of the TREX (transcription/export) complex important for transcriptional elongation and recruitment of mRNA export factors (PubMed:15314027, PubMed:20053728). Methylates the hnRNP HRB1, but does not influence its subcellular location (PubMed:9499403). Methylates the nucleolar proteins GAR1, NOP1 and NSR1 (PubMed:12756332). Methylates the snRNP SNP1 and modulates the cotranscriptional recruitment of splicing factors (PubMed:20823272). Dimethylates free histone H4 (HHF1/HHF2) at 'Arg-4' (H4R3me2a) and plays a role in preservation and establishment of silent chromatin domains (PubMed:12097318, PubMed:17158743). Mono- and dimethylates ribosomal protein S2 (RPS2) at 'Arg-11' (PubMed:20035717). Methylates the catalytic subunit of the SWI/SNF chromatin-remodeling complex SNF2 (PubMed:22997150)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQ34", "ec_number_list": "3.6.4.13;2.1.1.319;2.3.1.48;2.3.1.-", "go_molecular_function": "GO:0042802 identical protein binding;GO:0016274 protein-arginine N-methyltransferase activity;GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity;GO:0042054 histone methyltransferase activity;GO:0035241 protein-arginine omega-N monomethyltransferase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0060567 negative regulation of termination of DNA-templated transcription;GO:0006338 chromatin remodeling;GO:0006406 mRNA export from nucleus;GO:0006355 regulation of DNA-templated transcription;GO:0018216 peptidyl-arginine methylation", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "P38074-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38121-1", "uniprot_id": "DPOA2_YEAST", "mass": 78774.0, "length": 705, "protein_name": "DNA polymerase alpha subunit B", "gene_name": "POL12", "organism": "Yeast", "refseq_name": "DNA-directed DNA polymerase alpha subunit POL12", "refseq_ac": "NP_009518", "gene_names_uniprotkb": "POL12; YBL0414", "gene_names_refseq": "POL12", "protein_names_uniprotkb": "DNA polymerase alpha subunit B; DNA polymerase I subunit B; DNA polymerase alpha:primase complex p86 subunit; DNA polymerase-primase complex p74 subunit; Pol alpha-primase complex p86 subunit", "protein_names_refseq": "DNA-directed DNA polymerase alpha subunit POL12", "tax_id": 559292, "disease": "", "pathway": " (sce:YBL035C); (R-SCE-113501); (R-SCE-68952); (R-SCE-68962); (R-SCE-69091); (R-SCE-69166); (R-SCE-69183)", "pathway_count": 7, "publication_count": 20, "publication_id_list": "14562106;16675460;17563356;18407956;19494830;19684113;19779198;19795423;19823750;21126336;23749301;24374639;30516470;3061469;32597660;33481703;33491328;7813418;8091857;8621497", "class_list": "", "function": "Non-catalytic component of DNA polymerase alpha, which in a complex with DNA primase (DNA polymerase alpha:primase) constitutes a replicative polymerase. POL12 may play an essential role at the early stage of chromosomal DNA replication by coupling DNA polymerase alpha to the cellular replication machinery (By similarity). Interacts with MCM10., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 27, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VPW4", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005658 alpha DNA polymerase:primase complex;GO:0005634 nucleus;GO:0005635 nuclear envelope", "go_biological_process": "GO:0071897 DNA biosynthetic process;GO:0016233 telomere capping;GO:0006270 DNA replication initiation", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P38121-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38129-1", "uniprot_id": "TAF5_YEAST", "mass": 88968.0, "length": 798, "protein_name": "SAGA complex/transcription factor TFIID complex subunit TAF5", "gene_name": "TAF5", "organism": "Yeast", "refseq_name": "chromatin modification protein", "refseq_ac": "NP_009757", "gene_names_uniprotkb": "TAF5; TAF90; YBR1410", "gene_names_refseq": "TAF5; TAF90", "protein_names_uniprotkb": "SAGA complex/transcription factor TFIID complex subunit TAF5; TAFII-90; TBP-associated factor 5; TBP-associated factor 90 kDa; Transcription initiation factor TFIID subunit 5", "protein_names_refseq": "chromatin modification protein", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR198C); (R-SCE-674695); (R-SCE-6807505); (R-SCE-73776); (R-SCE-73779); (R-SCE-75953); (R-SCE-76042); (R-SCE-9907900)", "pathway_count": 8, "publication_count": 41, "publication_id_list": "10026213;10788514;10864329;11585915;12052880;12093743;12138208;12186975;12446794;12516863;12600943;14562106;15260971;15448131;15647753;17322287;17397863;17563356;18407956;19731963;19779198;19795423;19823750;20489023;23749301;24374639;25216679;28918900;28918903;30516470;31969703;32597660;33229814;33481703;33491328;33864814;7667272;7813418;7935765;7975899;9674426", "class_list": "", "function": "Functions as a component of both the DNA-binding general transcription initiation factor complex TFIID and the transcription coactivator SAGA complex (PubMed:10788514, PubMed:12052880, PubMed:25216679, PubMed:28918900). Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription (PubMed:12516863, PubMed:12600943, PubMed:15448131, PubMed:28918900). SAGA acts as a general cofactor required for essentially all RNA polymerase II transcription (PubMed:10864329, PubMed:25216679, PubMed:9674426). At the promoters, SAGA is required for transcription pre-initiation complex (PIC) recruitment. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (via core/TAF module) and promoter selectivity, interaction with transcription activators (via Tra1/SPT module), and chromatin modification through histone acetylation (via HAT module) and deubiquitination (via DUB module) (PubMed:31969703). SAGA preferentially acetylates histones H3 (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac) and H2B and deubiquitinates histone H2B (PubMed:10026213). SAGA interacts with DNA via upstream activating sequences (UASs) (PubMed:28918903). Also identified in a modified version of SAGA named SALSA or SLIK (PubMed:12186975, PubMed:12446794). The cleavage of SPT7 and the absence of the SPT8 subunit in SLIK neither drive any major conformational differences in its structure compared with SAGA, nor significantly affect HAT, DUB, or DNA-binding activities (PubMed:33864814)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 5, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 5, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 5, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 16, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "D6VQJ4", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0003682 chromatin binding;GO:0042802 identical protein binding;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005669 transcription factor TFIID complex;GO:0000124 SAGA complex;GO:0046695 SLIK (SAGA-like) complex", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006325 chromatin organization;GO:0006366 transcription by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter", "synthesized_glycan_count": 0, "hit_score": 4.8, "record_id": "P38129-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38132-1", "uniprot_id": "MCM7_YEAST", "mass": 94943.0, "length": 845, "protein_name": "DNA replication licensing factor MCM7", "gene_name": "MCM7", "organism": "Yeast", "refseq_name": "DNA replication licensing factor MCM7", "refseq_ac": "NP_009761", "gene_names_uniprotkb": "MCM7; CDC47; YBR1441", "gene_names_refseq": "CDC47; MCM7", "protein_names_uniprotkb": "DNA replication licensing factor MCM7; 3.6.4.12; Cell division control protein 47; Minichromosome maintenance protein 7", "protein_names_refseq": "DNA replication licensing factor MCM7", "tax_id": 559292, "disease": "pancreatic ductal carcinoma (Disease Ontology:DOID:3587); hepatocellular carcinoma (Disease Ontology:DOID:684); hyperthyroidism (Disease Ontology:DOID:7998)", "pathway": " (sce:YBR202W); (R-SCE-176187); (R-SCE-68867); (R-SCE-68962); (R-SCE-69052)", "pathway_count": 5, "publication_count": 24, "publication_id_list": "11875433;14562095;14562106;15023545;17330950;18407956;18657510;19684113;19779198;19795423;19823750;19896182;19910535;21070963;21126336;23749301;24374639;30516470;33481703;33491328;7708676;7813418;8368014;9154825", "class_list": "", "function": "Acts as a component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Once loaded onto DNA, double hexamers can slide on dsDNA in the absence of ATPase activity., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQK0", "ec_number_list": "2.7.11.22;2.7.11.1;3.6.4.13;5.6.2.3;3.6.4.10;2.7.7.-;3.6.-.-;5.6.2.4;2.7.7.7;3.6.4.-;5.6.1.4;3.1.11.-;3.6.4.12;3.6.4.6;5.6.2.5;3.6.1.-;2.3.2.27;3.1.-.-;3.4.24.-;3.6.5.-;2.7.4.3;7.2.2.-", "go_molecular_function": "GO:0003688 DNA replication origin binding;GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0017116 single-stranded DNA helicase activity", "go_cellular_component": "GO:0005656 nuclear pre-replicative complex;GO:0031261 DNA replication preinitiation complex;GO:0043596 nuclear replication fork;GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication;GO:0006271 DNA strand elongation involved in DNA replication;GO:0031509 subtelomeric heterochromatin formation;GO:0006260 DNA replication;GO:0006270 DNA replication initiation", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "P38132-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38164-1", "uniprot_id": "SEA4_YEAST", "mass": 117636.0, "length": 1038, "protein_name": "SEH-associated protein 4", "gene_name": "SEA4", "organism": "Yeast", "refseq_name": "Sea4p", "refseq_ac": "NP_009446", "gene_names_uniprotkb": "SEA4; YBL0808; YBL103C-A", "gene_names_refseq": "SEA4; YBL103C-A", "protein_names_uniprotkb": "SEH-associated protein 4", "protein_names_refseq": "Sea4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YBL104C)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "12748633;12775844;12844361;14562095;14562106;18407956;19779198;20489023;21126336;21454883;23749301;24374639;33229814;33481703;33491328;7502586;7813418", "class_list": "", "function": "Component of the SEA complex which coats the vacuolar membrane and is involved in intracellular trafficking, autophagy, response to nitrogen starvation, and amino acid biogenesis., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 4, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 4, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 4, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 20, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "D6VPP9;Q86ZS4", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005774 vacuolar membrane;GO:0035859 Seh1-associated complex", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0015031 protein transport;GO:1903432 regulation of TORC1 signaling", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "P38164-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38203-1", "uniprot_id": "LSM2_YEAST", "mass": 11163.0, "length": 95, "protein_name": "LSM complex subunit LSM2", "gene_name": "LSM2", "organism": "Yeast", "refseq_name": "Sm-like protein LSM2", "refseq_ac": "NP_009527", "gene_names_uniprotkb": "LSM2; SMX5; SNP3; YBL0425", "gene_names_refseq": "LSM2; SMX5; SNP3", "protein_names_uniprotkb": "LSM complex subunit LSM2; Small nuclear ribonucleoprotein D homolog SNP3", "protein_names_refseq": "Sm-like protein LSM2", "tax_id": 559292, "disease": "", "pathway": " (sce:YBL026W); (R-SCE-430039)", "pathway_count": 2, "publication_count": 22, "publication_id_list": "10369684;10428970;10449419;10747033;12077351;12438310;14562106;14627812;15075370;15485930;24139796;24240276;24247251;24374639;24513854;29717126;30059503;33481703;33491328;34965436;7725803;7813418", "class_list": "", "function": "Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner (PubMed:10747033, PubMed:12077351, PubMed:12438310, PubMed:14627812, PubMed:24513854, PubMed:24247251). Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation by activating the decapping step (PubMed:10747033, PubMed:24513854, PubMed:24247251). Together with PAT1, the LSM1-LSM7 complex binds to osmotic stress-activated mRNAs to attenuate the osmotic stress response, probably by limiting ribosome access to the mRNA and consequently translation (PubMed:30059503). Component of the nuclear LSM2-LSM8 complex, which is involved in spliceosome assembly (PubMed:10747033, PubMed:12077351, PubMed:12438310, PubMed:14627812). The LSM2-LSM8 complex plays a role in the biogenesis of the spliceosomal U4/U6-U5 tri-snRNP complex by accelerating PRP24-mediated annealing of U4/U6 di-snRNA (PubMed:10747033, PubMed:24240276, PubMed:29717126). The LSM2-LSM8 complex binds U6 snRNA terminating with a non-cyclic 3' phosphate group (PubMed:29717126). LSM2-LSM8 is probably also involved in degradation of nuclear pre-mRNA by targeting them for decapping (PubMed:15485930). LSM2-LSM8 could be involved in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA, although involvement may be indirect (PubMed:12077351, PubMed:12438310, PubMed:15075370). In a complex that probably contains LSM2-LSM7, but not LSM1 or LSM8, associates with the precursor of the RNA component of RNase P (pre-P RNA) and may be involved in maturing pre-P RNA; the complex also associates with snoRNA SNR5 (PubMed:10369684, PubMed:15075370)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VPX4", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0000932 P-body;GO:0071013 catalytic step 2 spliceosome", "go_biological_process": "GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0008033 tRNA processing;GO:0000398 mRNA splicing, via spliceosome;GO:0006364 rRNA processing", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "P38203-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38261-1", "uniprot_id": "EXO84_YEAST", "mass": 85538.0, "length": 753, "protein_name": "Exocyst complex component EXO84", "gene_name": "EXO84", "organism": "Yeast", "refseq_name": "exocyst subunit EXO84", "refseq_ac": "NP_009660", "gene_names_uniprotkb": "EXO84; USA3; YBR0831", "gene_names_refseq": "EXO84; USA3", "protein_names_uniprotkb": "Exocyst complex component EXO84; Exocyst complex protein of 84 kDa; U1 SNP1-associating protein 3", "protein_names_refseq": "exocyst subunit EXO84", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR102C); (R-SCE-264876)", "pathway_count": 2, "publication_count": 23, "publication_id_list": "10438536;11425851;12872131;14562095;15583031;15788396;16249794;17287358;17563356;18407956;19779198;20702584;21126336;21177495;22814378;23749301;24374639;31171719;32597660;33481703;33491328;7813418;7900426", "class_list": "", "function": "Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Plays a role in both the assembly of the exocyst and the polarization of this complex to specific sites of the plasma membrane for exocytosis and to the budding site. Also involved in assembly of the spliceosome., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 29, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQA1", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0030133 transport vesicle;GO:0000145 exocyst;GO:0000131 incipient cellular bud site;GO:0005628 prospore membrane;GO:0005934 cellular bud tip", "go_biological_process": "GO:0051601 exocyst localization;GO:0015031 protein transport;GO:0008104 intracellular protein localization;GO:0006887 exocytosis;GO:0000245 spliceosomal complex assembly", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P38261-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38264-1", "uniprot_id": "PHO88_YEAST", "mass": 21137.0, "length": 188, "protein_name": "SRP-independent targeting protein 3", "gene_name": "PHO88", "organism": "Yeast", "refseq_name": "Snd3p", "refseq_ac": "NP_009664", "gene_names_uniprotkb": "PHO88; SND3; YBR0835", "gene_names_refseq": "PHO88; SND3", "protein_names_uniprotkb": "SRP-independent targeting protein 3; Inorganic phosphate transport protein PHO88; Phosphate metabolism protein PHO88", "protein_names_refseq": "Snd3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR106W)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "14562095;14562106;14576278;16552446;17322287;18407956;20702584;21126336;23749301;24374639;27905431;32597660;33481703;33491328;7813418;7900426;8709965", "class_list": "", "function": "Functions in the SND pathway, a SRP (signal recognition particle) and GET (guided entry of tail-anchored proteins) independent pathway for targeting a broad range of substrate proteins to the endoplasmic reticulum. SND functions in parallel to GET in targeting proteins with downstream hydrophobic motifs (PubMed:27905431). Involved in inorganic phosphate uptake (PubMed:8709965). Also involved in telomere length regulation and maintenance (PubMed:16552446)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQA5", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0015031 protein transport;GO:0051604 protein maturation;GO:0006817 phosphate ion transport;GO:0045047 protein targeting to ER", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P38264-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38283-1", "uniprot_id": "INCE_YEAST", "mass": 79186.0, "length": 698, "protein_name": "Inner centromere protein SLI15", "gene_name": "SLI15", "organism": "Yeast", "refseq_name": "Sli15p", "refseq_ac": "NP_009714", "gene_names_uniprotkb": "SLI15; YBR1206", "gene_names_refseq": "SLI15", "protein_names_uniprotkb": "Inner centromere protein SLI15; INCENP-related protein SLI15", "protein_names_refseq": "Sli15p", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR156C)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "10385519;11724818;11853667;12408861;14562106;17287358;18407956;19684113;19779198;19795423;19823750;20702584;21126336;23749301;24374639;30516470;32597660;33481703;33491328;34502421;7483850;7813418;8488729", "class_list": "", "function": "Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis (By similarity). Stimulates IPL1 kinase activity and facilitates its association with the mitotic spindle. Has a role in attaching the kinetochores to the microtubules and ensuring that sister kinetochores connect to opposite poles (PubMed:10385519, PubMed:11724818, PubMed:11853667)., [UniProtKB, PubMed, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 62, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQF1", "ec_number_list": "", "go_molecular_function": "GO:0030295 protein kinase activator activity", "go_cellular_component": "GO:0005828 kinetochore microtubule;GO:0005634 nucleus;GO:0051233 spindle midzone;GO:0000776 kinetochore;GO:0005876 spindle microtubule", "go_biological_process": "GO:0007059 chromosome segregation;GO:0032147 activation of protein kinase activity;GO:0032185 septin cytoskeleton organization;GO:0032465 regulation of cytokinesis;GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P38283-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38304-1", "uniprot_id": "MED8_YEAST", "mass": 25268.0, "length": 223, "protein_name": "Mediator of RNA polymerase II transcription subunit 8", "gene_name": "MED8", "organism": "Yeast", "refseq_name": "RNA polymerase II mediator complex subunit MED8", "refseq_ac": "NP_009752", "gene_names_uniprotkb": "MED8; YBR1403", "gene_names_refseq": "MED8", "protein_names_uniprotkb": "Mediator of RNA polymerase II transcription subunit 8; Mediator complex subunit 8", "protein_names_refseq": "RNA polymerase II mediator complex subunit MED8", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR193C)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "10526178;11555651;12054864;12191485;14562106;15175151;15477388;16002404;16076843;16263706;16885025;16964259;17192271;17322287;18407956;19779198;24374639;33229814;33491328;7813418;8346681;9420330;9918841", "class_list": "", "function": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. The Mediator complex unfolds to an extended conformation and partially surrounds RNA polymerase II, specifically interacting with the unphosphorylated form of the C-terminal domain (CTD) of RNA polymerase II. The Mediator complex dissociates from the RNA polymerase II holoenzyme and stays at the promoter when transcriptional elongation begins. MED8 binds to the consensus sequence 5'-[AC][AG]GAAAT-3' in both the UAS of SUC2 and the DRS2 of HXK2., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 6, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 6, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 6, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6VQI7", "ec_number_list": "", "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0003714 transcription corepressor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003712 transcription coregulator activity;GO:0017025 TBP-class protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016592 mediator complex;GO:0070847 core mediator complex", "go_biological_process": "GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0032968 positive regulation of transcription elongation by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 3.1, "record_id": "P38304-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38315-1", "uniprot_id": "YBP1_YEAST", "mass": 77741.0, "length": 674, "protein_name": "YAP1-binding protein 1", "gene_name": "YBP1", "organism": "Yeast", "refseq_name": "Ybp1p", "refseq_ac": "NP_009775", "gene_names_uniprotkb": "YBP1; YBR1505", "gene_names_refseq": "YBP1", "protein_names_uniprotkb": "YAP1-binding protein 1; Activator of YAP1", "protein_names_refseq": "Ybp1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR216C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "11283351;12743123;14562095;14562106;15075262;19684113;23749301;24374639;33491328;7813418", "class_list": "", "function": "Involved in oxidative stress response and redox homeostasis. Required for hydrogen peroxide-induced oxidation and nuclear localization (activation) of YAP1. Functions probably in concert with HYP1/GPX3, the actual YAP1 modifying enzyme. YBP1 is not required for HYP1/GPX3-independent, diamide-induced oxidation of YAP1., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQL2", "ec_number_list": "", "go_molecular_function": "GO:0015035 protein-disulfide reductase activity;GO:0140297 DNA-binding transcription factor binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0034599 cellular response to oxidative stress;GO:0018158 protein oxidation;GO:0065003 protein-containing complex assembly", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P38315-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38333-1", "uniprot_id": "ENP1_YEAST", "mass": 55137.0, "length": 483, "protein_name": "Essential nuclear protein 1", "gene_name": "ENP1", "organism": "Yeast", "refseq_name": "snoRNA-binding rRNA-processing protein ENP1", "refseq_ac": "NP_009806", "gene_names_uniprotkb": "ENP1; MEG1; YBR1635", "gene_names_refseq": "ENP1; MEG1", "protein_names_uniprotkb": "Essential nuclear protein 1", "protein_names_refseq": "snoRNA-binding rRNA-processing protein ENP1", "tax_id": 559292, "disease": "", "pathway": " (sce:YBR247C); (R-SCE-6791226)", "pathway_count": 2, "publication_count": 18, "publication_id_list": "12628929;14562106;16159874;17563356;18407956;19779198;19795423;19823750;20190278;21177495;23749301;24374639;32138239;32597660;33481703;33491328;7813418;9034325", "class_list": "", "function": "Required for normal export of the pre-40S particles from the nucleus to the cytoplasm. Its subcellular location and association with pre-40S subunit shifts from mixed cytoplasm/nucleus to all nuclear in RPS19 disruptions, suggesting it acts after the ribosomal protein., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 17, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQP3", "ec_number_list": "", "go_molecular_function": "GO:0030515 snoRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0030688 preribosome, small subunit precursor;GO:0030686 90S preribosome", "go_biological_process": "GO:0016973 poly(A)+ mRNA export from nucleus;GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364 rRNA processing;GO:0030490 maturation of SSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P38333-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38349-1", "uniprot_id": "UBX7_YEAST", "mass": 50031.0, "length": 436, "protein_name": "UBX domain-containing protein 7", "gene_name": "UBX7", "organism": "Yeast", "refseq_name": "Ubx7p", "refseq_ac": "NP_009832", "gene_names_uniprotkb": "UBX7; YBR1741", "gene_names_refseq": "CUI3; UBX7", "protein_names_uniprotkb": "UBX domain-containing protein 7", "protein_names_refseq": "Ubx7p", "tax_id": 559292, "disease": "candidiasis (Disease Ontology:DOID:1508)", "pathway": " (sce:YBR273C)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "14562095;14562106;15258615;18407956;19779198;20702584;21126336;21177495;22106047;22814378;23749301;24374639;32597660;33481703;33491328;34965436;7813418", "class_list": "", "function": "Involved in CDC48-dependent protein degradation through the ubiquitin/proteasome pathway., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VQR9", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0006511 ubiquitin-dependent protein catabolic process;GO:0036503 ERAD pathway;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P38349-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38431-1", "uniprot_id": "IF5_YEAST", "mass": 45261.0, "length": 405, "protein_name": "Eukaryotic translation initiation factor 5", "gene_name": "TIF5", "organism": "Yeast", "refseq_name": "translation initiation factor eIF5", "refseq_ac": "NP_015366", "gene_names_uniprotkb": "TIF5; YP3085.05", "gene_names_refseq": "SUI5; TIF5", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 5; eIF-5", "protein_names_refseq": "translation initiation factor eIF5", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR041W); (R-SCE-72702)", "pathway_count": 2, "publication_count": 27, "publication_id_list": "10075937;11875433;12651896;14562106;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;21280672;23749301;24374639;32027465;32597660;33481703;33491328;35031321;8486705;9169875;9671501;9730282", "class_list": "", "function": "Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]). eIF-5 is essential for cell viability., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 24, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W450", "ec_number_list": "", "go_molecular_function": "GO:0071074 eukaryotic initiation factor eIF2 binding;GO:0005096 GTPase activator activity;GO:0005525 GTP binding;GO:0003743 translation initiation factor activity;GO:0005092 GDP-dissociation inhibitor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0033290 eukaryotic 48S preinitiation complex;GO:0043614 multi-eIF complex", "go_biological_process": "GO:0045947 negative regulation of translational initiation;GO:0006446 regulation of translational initiation;GO:0001732 formation of cytoplasmic translation initiation complex;GO:0042256 cytosolic ribosome assembly", "synthesized_glycan_count": 0, "hit_score": 2.8, "record_id": "P38431-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38615-1", "uniprot_id": "RIM11_YEAST", "mass": 43005.0, "length": 370, "protein_name": "Serine/threonine-protein kinase RIM11/MSD1", "gene_name": "RIM11", "organism": "Yeast", "refseq_name": "serine/threonine protein kinase RIM11", "refseq_ac": "NP_013859", "gene_names_uniprotkb": "RIM11; GSK3; MDS1; YM9375.08", "gene_names_refseq": "GSK3; MDS1; RIM11", "protein_names_uniprotkb": "Serine/threonine-protein kinase RIM11/MSD1; 2.7.11.1; Regulator of IME2 protein 11", "protein_names_refseq": "serine/threonine protein kinase RIM11", "tax_id": 559292, "disease": "diabetic encephalopathy (Disease Ontology:DOID:0050850); colorectal adenocarcinoma (Disease Ontology:DOID:0050861); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); Parkinsonism (Disease Ontology:DOID:0080855); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); heart disease (Disease Ontology:DOID:114); sciatic neuropathy (Disease Ontology:DOID:11446); Parkinson's disease (Disease Ontology:DOID:14330); depressive disorder (Disease Ontology:DOID:1596); status epilepticus (Disease Ontology:DOID:1824); colon cancer (Disease Ontology:DOID:219); endometrial carcinoma (Disease Ontology:DOID:2871); substance-related disorder (Disease Ontology:DOID:303); bipolar disorder (Disease Ontology:DOID:3312); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); middle cerebral artery infarction (Disease Ontology:DOID:3525); schizophrenia (Disease Ontology:DOID:5419); myocardial infarction (Disease Ontology:DOID:5844); vascular dementia (Disease Ontology:DOID:8725); degenerative disc disease (Disease Ontology:DOID:90); type 2 diabetes mellitus (Disease Ontology:DOID:9352); acute myocardial infarction (Disease Ontology:DOID:9408)", "pathway": " (sce:YMR139W); (R-SCE-3371453); (R-SCE-69601); (R-SCE-9856649)", "pathway_count": 4, "publication_count": 25, "publication_id_list": "10679022;14562106;15665377;17322287;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20489023;20702584;21177495;21460040;22218487;23749301;24374639;32597660;33481703;33491328;7969131;8244030;8264650;9169872", "class_list": "", "function": "Serine/threonine protein kinase that is thought to function in regulating kinetochore activity and entry into meiosis. Could phosphorylate IME1., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 23, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZW2;Q6Q5K4", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;3.1.3.48;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004712 protein serine/threonine/tyrosine kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0007165 signal transduction;GO:0030154 cell differentiation;GO:0030437 ascospore formation", "synthesized_glycan_count": 0, "hit_score": 2.6, "record_id": "P38615-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38753-1", "uniprot_id": "HSE1_YEAST", "mass": 51161.0, "length": 452, "protein_name": "Class E vacuolar protein-sorting machinery protein HSE1", "gene_name": "HSE1", "organism": "Yeast", "refseq_name": "ESCRT-0 subunit protein HSE1", "refseq_ac": "NP_011861", "gene_names_uniprotkb": "HSE1", "gene_names_refseq": "HSE1", "protein_names_uniprotkb": "Class E vacuolar protein-sorting machinery protein HSE1", "protein_names_refseq": "ESCRT-0 subunit protein HSE1", "tax_id": 559292, "disease": "polycystic kidney disease (Disease Ontology:DOID:0080322)", "pathway": " (sce:YHL002W); (R-SCE-9013420)", "pathway_count": 2, "publication_count": 22, "publication_id_list": "12055639;14562095;14562106;14581452;15086794;17079730;17330950;17563356;18407956;18508771;19779198;19795423;19823750;20702584;21177495;22814378;23749301;24374639;32597660;33481703;33491328;8091229", "class_list": "", "function": "Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DKR2", "ec_number_list": "", "go_molecular_function": "GO:0019904 protein domain specific binding;GO:0046982 protein heterodimerization activity;GO:0035091 phosphatidylinositol binding;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0033565 ESCRT-0 complex;GO:0005768 endosome;GO:0010008 endosome membrane;GO:0005774 vacuolar membrane;GO:0032991 protein-containing complex", "go_biological_process": "GO:0071985 multivesicular body sorting pathway;GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0009306 protein secretion;GO:0045324 late endosome to vacuole transport;GO:1903319 positive regulation of protein maturation", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "P38753-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38757-1", "uniprot_id": "NEM1_YEAST", "mass": 50642.0, "length": 446, "protein_name": "Nuclear envelope morphology protein 1", "gene_name": "NEM1", "organism": "Yeast", "refseq_name": "Nem1-Spo7 phosphatase catalytic subunit NEM1", "refseq_ac": "NP_011867", "gene_names_uniprotkb": "NEM1", "gene_names_refseq": "NEM1", "protein_names_uniprotkb": "Nuclear envelope morphology protein 1; 3.1.3.16", "protein_names_refseq": "Nem1-Spo7 phosphatase catalytic subunit NEM1", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR004C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "14562106;15889145;17322287;19779198;24374639;25117580;29305265;30201607;31501244;33491328;8091229;9822591", "class_list": "", "function": "Catalytic component of the NEM1-SPO7 complex which acts as a phosphatase and dephosphorylates the phosphatidic acid phosphohydrolase PAH1 (PubMed:15889145). Essential for the formation of a spherical nucleus and meiotic division (PubMed:9822591). The NEM1-SPOo7 protein phosphatase is required for efficient mitophagy under prolonged respiration, as well as for reticulophagy and pexophagy (PubMed:29305265)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DKU7", "ec_number_list": "3.1.3.16;3.1.3.43;3.1.3.48", "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005811 lipid droplet;GO:0016020 membrane;GO:0031965 nuclear membrane", "go_biological_process": "GO:0046889 positive regulation of lipid biosynthetic process;GO:0006998 nuclear envelope organization;GO:0071072 negative regulation of phospholipid biosynthetic process;GO:0140042 lipid droplet formation;GO:0071071 regulation of phospholipid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P38757-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38785-1", "uniprot_id": "GIC1_YEAST", "mass": 35238.0, "length": 314, "protein_name": "GTPase-interacting component 1", "gene_name": "GIC1", "organism": "Yeast", "refseq_name": "Gic1p", "refseq_ac": "NP_011928", "gene_names_uniprotkb": "GIC1", "gene_names_refseq": "GIC1", "protein_names_uniprotkb": "GTPase-interacting component 1", "protein_names_refseq": "Gic1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR061C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562106;23749301;24374639;33481703;33491328;8091229;9367979;9367980", "class_list": "", "function": "Required for cell size and shape control, bud site selection, bud emergence, actin cytoskeletal organization, mitotic spindle orientation/positioning, and mating projection formation in response to mating pheromone., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DL10", "ec_number_list": "", "go_molecular_function": "GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0005938 cell cortex;GO:0000131 incipient cellular bud site", "go_biological_process": "GO:0008360 regulation of cell shape;GO:0007096 regulation of exit from mitosis;GO:0030010 establishment of cell polarity;GO:0032488 Cdc42 protein signal transduction;GO:0031106 septin ring organization", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P38785-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38791-1", "uniprot_id": "DHYS_YEAST", "mass": 42892.0, "length": 387, "protein_name": "Deoxyhypusine synthase", "gene_name": "DYS1", "organism": "Yeast", "refseq_name": "deoxyhypusine synthase", "refseq_ac": "NP_011935", "gene_names_uniprotkb": "DYS1", "gene_names_refseq": "DYS1", "protein_names_uniprotkb": "Deoxyhypusine synthase; 2.5.1.46; DHS", "protein_names_refseq": "deoxyhypusine synthase", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR068W); (R-SCE-204626)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "14562106;17322287;19795423;19823750;23749301;24374639;33481703;33491328;7629166;8091229;8612813", "class_list": "", "function": "Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DL17", "ec_number_list": "2.5.1.46", "go_molecular_function": "GO:0034038 deoxyhypusine synthase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0008216 spermidine metabolic process;GO:0008612 peptidyl-lysine modification to peptidyl-hypusine", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P38791-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38794-1", "uniprot_id": "PCL5_YEAST", "mass": 26467.0, "length": 229, "protein_name": "PHO85 cyclin-5", "gene_name": "PCL5", "organism": "Yeast", "refseq_name": "Pcl5p", "refseq_ac": "NP_011938", "gene_names_uniprotkb": "PCL5; H8025.1", "gene_names_refseq": "PCL5", "protein_names_uniprotkb": "PHO85 cyclin-5; G1/S-specific cyclin PCL5", "protein_names_refseq": "Pcl5p", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR071W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "12101234;17322287;18794371;24374639;33481703;8091229;9032248", "class_list": "", "function": "Cyclin partner of the cyclin-dependent kinase (CDK) PHO85. Positively controls degradation of transcription factor GCN4 under favorable growth conditions. The PCL5-PHO85 cyclin-CDK holoenzyme phosphorylates GCN4, which is required for its degradation by the E3 ubiquitin ligase complex SCF(Cdc4). Amino acid starvation reduces PCL5-PHO85-associated GCN4 kinase activity and leads to stabilization of GCN4., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DL20", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding;GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000307 cyclin-dependent protein kinase holoenzyme complex", "go_biological_process": "GO:0051301 cell division;GO:0031647 regulation of protein stability;GO:0016242 negative regulation of macroautophagy", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P38794-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38796-1", "uniprot_id": "PPME1_YEAST", "mass": 44888.0, "length": 400, "protein_name": "Protein phosphatase methylesterase 1", "gene_name": "PPE1", "organism": "Yeast", "refseq_name": "phosphoprotein phosphatase methylesterase 1", "refseq_ac": "NP_011942", "gene_names_uniprotkb": "PPE1", "gene_names_refseq": "PPE1", "protein_names_uniprotkb": "Protein phosphatase methylesterase 1; 3.1.1.89; PME-1; Yms2", "protein_names_refseq": "phosphoprotein phosphatase methylesterase 1", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR075C); (R-SCE-69273)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "11060018;14645503;15022016;15447631;24374639;28154081;8091229;9151978", "class_list": "", "function": "Demethylates proteins that have been reversibly carboxymethylated. Demethylates the phosphatase PP2A catalytic subunits PPH21 and PPH22. Forms inactive complexes (PP2Ai) with phosphatase PP2A-like catalytic subunits. Involved in the regulation of cell cycle progression at START., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DL25", "ec_number_list": "3.1.3.16;3.1.1.89", "go_molecular_function": "GO:0051723 protein methylesterase activity", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit", "go_biological_process": "GO:1990577 C-terminal protein demethylation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P38796-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38797-1", "uniprot_id": "PP2C7_YEAST", "mass": 37782.0, "length": 343, "protein_name": "Protein phosphatase 2C homolog 7, mitochondrial", "gene_name": "PTC7", "organism": "Yeast", "refseq_name": "type 2C protein phosphatase PTC7", "refseq_ac": "NP_011943", "gene_names_uniprotkb": "PTC7", "gene_names_refseq": "PTC7", "protein_names_uniprotkb": "Protein phosphatase 2C homolog 7, mitochondrial; 3.1.3.16; PP2C-7", "protein_names_refseq": "type 2C protein phosphatase PTC7", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR076W)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "11327310;12220683;14576278;17244705;17351133;22814378;23940037;24374639;28076776;30267671;8091229", "class_list": "", "function": "Protein phosphatase which positively regulates biosynthesis of the ubiquinone, coenzyme Q (PubMed:12220683, PubMed:23940037, PubMed:28076776, PubMed:30267671). Dephosphorylates and activates the ubiquinone biosynthesis protein CAT5/COQ7 (PubMed:23940037, PubMed:30267671). Also dephosphorylates CIT1 on 'Ser-462', which leads to its activation (PubMed:28076776)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A2TBN2;D3DL26;Q06HN3", "ec_number_list": "3.1.3.16;3.1.3.43;3.1.3.48", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity;GO:0004721 phosphoprotein phosphatase activity", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005739 mitochondrion", "go_biological_process": "GO:0070262 peptidyl-serine dephosphorylation;GO:0006470 protein dephosphorylation;GO:1904775 positive regulation of ubiquinone biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P38797-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38826-1", "uniprot_id": "ORC6_YEAST", "mass": 50296.0, "length": 435, "protein_name": "Origin recognition complex subunit 6", "gene_name": "ORC6", "organism": "Yeast", "refseq_name": "origin recognition complex subunit 6", "refseq_ac": "NP_011986", "gene_names_uniprotkb": "ORC6; AAP1", "gene_names_refseq": "ORC6", "protein_names_uniprotkb": "Origin recognition complex subunit 6; ACS-associated protein 1; Origin recognition complex 50 kDa subunit", "protein_names_refseq": "origin recognition complex subunit 6", "tax_id": 559292, "disease": "Meier-Gorlin syndrome (Disease Ontology:DOID:0060306)", "pathway": " (sce:YHR118C)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "14562106;15665377;17287358;17563356;17825064;18006685;18407956;19779198;19795423;19823750;20702584;21126336;21177495;21289063;22218487;23749301;24374639;32597660;33481703;33491328;34088668;8091229;8266075", "class_list": "", "function": "Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcriptional silencing. Binds to the ARS consensus sequence (ACS) of origins of replication., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 26, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DL68", "ec_number_list": "", "go_molecular_function": "GO:0003688 DNA replication origin binding", "go_cellular_component": "GO:0005656 nuclear pre-replicative complex;GO:0031261 DNA replication preinitiation complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005664 nuclear origin of replication recognition complex", "go_biological_process": "GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication;GO:0006270 DNA replication initiation;GO:0030466 silent mating-type cassette heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P38826-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38856-1", "uniprot_id": "AP18A_YEAST", "mass": 71660.0, "length": 637, "protein_name": "Clathrin coat assembly protein AP180A", "gene_name": "YAP1801", "organism": "Yeast", "refseq_name": "Yap1801p", "refseq_ac": "NP_012031", "gene_names_uniprotkb": "YAP1801", "gene_names_refseq": "YAP1801", "protein_names_uniprotkb": "Clathrin coat assembly protein AP180A", "protein_names_refseq": "Yap1801p", "tax_id": 559292, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); acute myeloid leukemia (Disease Ontology:DOID:9119)", "pathway": " (sce:YHR161C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "13679512;14562095;14562106;14704157;18407956;19795423;19823750;24374639;33481703;33491328;8091229;9531549", "class_list": "", "function": "Involved in endocytosis and clathrin cage assembly., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLB0", "ec_number_list": "", "go_molecular_function": "GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0005545 1-phosphatidylinositol binding;GO:0030276 clathrin binding;GO:0000149 SNARE binding;GO:0032050 clathrin heavy chain binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005905 clathrin-coated pit;GO:0030136 clathrin-coated vesicle;GO:0005628 prospore membrane;GO:0005935 cellular bud neck", "go_biological_process": "GO:0006897 endocytosis;GO:0006900 vesicle budding from membrane;GO:0048268 clathrin coat assembly;GO:0072583 clathrin-dependent endocytosis", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P38856-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38859-1", "uniprot_id": "DNA2_YEAST", "mass": 171694.0, "length": 1522, "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "organism": "Yeast", "refseq_name": "bifunctional ATP-dependent DNA helicase/ssDNA endodeoxyribonuclease DNA2", "refseq_ac": "NP_012034", "gene_names_uniprotkb": "DNA2", "gene_names_refseq": "DNA2; WEB2", "protein_names_uniprotkb": "DNA replication ATP-dependent helicase/nuclease DNA2; DNA 5'-3' helicase DNA2", "protein_names_refseq": "bifunctional ATP-dependent DNA helicase/ssDNA endodeoxyribonuclease DNA2", "tax_id": 559292, "disease": "Seckel syndrome (Disease Ontology:DOID:0050569); isolated growth hormone deficiency type IA (Disease Ontology:DOID:0060873); Seckel syndrome 8 (Disease Ontology:DOID:0070009); autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 6 (Disease Ontology:DOID:0111519); microcephaly (Disease Ontology:DOID:10907); cancer (Disease Ontology:DOID:162); Bloom syndrome (Disease Ontology:DOID:2717); Werner syndrome (Disease Ontology:DOID:5688); mitochondrial myopathy (Disease Ontology:DOID:699)", "pathway": " (sce:YHR164C)", "pathway_count": 1, "publication_count": 25, "publication_id_list": "15448135;17563356;18407956;18805091;19520826;19684113;19779198;19795423;19823750;20190278;20702584;20811461;20929864;21126336;21841787;22684504;23749301;24374639;32597660;32638513;33481703;33491328;7644470;8091229;9756935", "class_list": "", "function": "Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA. Possesses different enzymatic activities, such as single-stranded DNA (ssDNA)-dependent ATPase (PubMed:7644470, PubMed:9756935), 5'-3' helicase (PubMed:7644470, PubMed:9756935) and single-strand endodeoxyribonuclease activities (PubMed:7644470, PubMed:9756935). While the ATPase and endonuclease activities are well-defined and play a key role in Okazaki fragments processing and DSB repair, the 5'-3' DNA helicase activity is atypical: it cannot load onto its tracking strand internally and has an absolute free 5'-end requirement (PubMed:20929864). Helicase activity may promote the motion of DNA2 on the flap, helping the nuclease function., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 36, "reported_mutagensis": 13, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLB3", "ec_number_list": "3.6.4.13;5.6.2.3;3.6.4.10;3.6.-.-;5.6.2.4;3.6.4.-;5.6.1.4;3.6.4.12;3.6.4.6;5.6.2.5;3.6.1.-;2.3.2.27;3.1.-.-;3.4.24.-;3.6.5.-;2.7.4.3;2.7.11.1;7.2.2.-", "go_molecular_function": "GO:0032448 DNA hairpin binding;GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0035861 site of double-strand break;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0006273 lagging strand elongation;GO:0006281 DNA repair;GO:0000723 telomere maintenance;GO:0006974 DNA damage response;GO:0000706 meiotic DNA double-strand break processing", "synthesized_glycan_count": 0, "hit_score": 2.6, "record_id": "P38859-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38879-1", "uniprot_id": "NACA_YEAST", "mass": 18709.0, "length": 174, "protein_name": "Nascent polypeptide-associated complex subunit alpha", "gene_name": "EGD2", "organism": "Yeast", "refseq_name": "Egd2p", "refseq_ac": "NP_012063", "gene_names_uniprotkb": "EGD2", "gene_names_refseq": "EGD2", "protein_names_uniprotkb": "Nascent polypeptide-associated complex subunit alpha; Alpha-NAC; GAL4 DNA-binding enhancer protein 2; NAC-alpha", "protein_names_refseq": "Egd2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR193C)", "pathway_count": 1, "publication_count": 24, "publication_id_list": "10219998;10512867;10518932;11683391;11959135;14562095;14562106;16926149;17287358;17322287;18407956;19779198;21126336;22218487;22814378;23749301;24374639;24909858;33481703;33491328;8091229;8509419;8522175;9482879", "class_list": "", "function": "Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLE1", "ec_number_list": "", "go_molecular_function": "GO:0051082 unfolded protein binding;GO:0080025 phosphatidylinositol-3,5-bisphosphate binding;GO:0070273 phosphatidylinositol-4-phosphate binding;GO:0032266 phosphatidylinositol-3-phosphate binding;GO:0070300 phosphatidic acid binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005854 nascent polypeptide-associated complex", "go_biological_process": "GO:0051083 'de novo' cotranslational protein folding;GO:0015031 protein transport;GO:0006612 protein targeting to membrane;GO:0006613 cotranslational protein targeting to membrane", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "P38879-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38888-1", "uniprot_id": "MNL1_YEAST", "mass": 91246.0, "length": 796, "protein_name": "ER degradation-enhancing alpha-mannosidase-like protein 1", "gene_name": "MNL1", "organism": "Yeast", "refseq_name": "alpha-1,2-mannosidase MNL1", "refseq_ac": "NP_012074", "gene_names_uniprotkb": "MNL1; HTM1", "gene_names_refseq": "HTM1; MNL1", "protein_names_uniprotkb": "ER degradation-enhancing alpha-mannosidase-like protein 1; 3.2.1.210; 3.2.1.24", "protein_names_refseq": "alpha-1,2-mannosidase MNL1", "tax_id": 559292, "disease": "cystic fibrosis (Disease Ontology:DOID:1485)", "pathway": " (sce:YHR204W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "11254655;11375935;14562095;14562106;15078901;15215312;15809311;19124653;21700223;24374639;39930008;8091229", "class_list": "", "function": "Alpha-1,2-specific exomannosidase involved in endoplasmic reticulum-associated degradation (ERAD) via delivering fs misfolded glycoproteins to proteasomes (PubMed:11254655, PubMed:11375935, PubMed:15078901, PubMed:15215312, PubMed:15809311). Forms a complex with PDI1 to process unfolded protein-bound Man8GlcNAc2 oligosaccharides to Man7GlcNAc2, promoting degradation in unfolded protein response. The MNL11-PDI1 complex initiates ERAD by performing two crucial reactions on glycoprotein substrates, trimming the glycan and reducing disulfide bonds. The mannosidase component MNL1 uses its CTD to act on globular, misfolded proteins, generating an exposed alpha1,6-mannose residue that serves as a degradation signal. In a subsequent reaction, the PDI11 component of the complex uses GSH to reduce the disulfides of the demannosylated protein, gen- erating an unfolded polypeptide that can be retrotranslocated across the ER membrane (PubMed:19124653, PubMed:21700223, PubMed:39930008)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "D3DLF3", "ec_number_list": "3.2.1.24;3.2.1.210", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0030246 carbohydrate binding;GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005788 endoplasmic reticulum lumen;GO:0016020 membrane;GO:0044322 endoplasmic reticulum quality control compartment", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:1904380 endoplasmic reticulum mannose trimming;GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response;GO:0006986 response to unfolded protein;GO:0097466 ubiquitin-dependent glycoprotein ERAD pathway", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P38888-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38902-1", "uniprot_id": "RPB11_YEAST", "mass": 13616.0, "length": 120, "protein_name": "DNA-directed RNA polymerase II subunit RPB11", "gene_name": "RPB11", "organism": "Yeast", "refseq_name": "DNA-directed RNA polymerase II core subunit RPB11", "refseq_ac": "NP_014638", "gene_names_uniprotkb": "RPB11", "gene_names_refseq": "RPB11", "protein_names_uniprotkb": "DNA-directed RNA polymerase II subunit RPB11; B13.6; DNA-directed RNA polymerase II 13.6 kDa polypeptide; RNA polymerase II subunit B11", "protein_names_refseq": "DNA-directed RNA polymerase II core subunit RPB11", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL005C); (R-SCE-113418); (R-SCE-674695); (R-SCE-6781823); (R-SCE-6782135); (R-SCE-6782210); (R-SCE-6796648); (R-SCE-6807505); (R-SCE-72086); (R-SCE-72203); (R-SCE-73776); (R-SCE-73779); (R-SCE-75953); (R-SCE-76042); (R-SCE-77075); (R-SCE-9018519)", "pathway_count": 16, "publication_count": 19, "publication_id_list": "11313498;11313499;11805306;12746495;12746498;12914699;14562106;14580350;14963322;15537538;15591044;15610738;16341226;16537912;16765890;17322287;24374639;8508029;9169874", "class_list": "", "function": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft. Seems to be involved transcript termination., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W262", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0046983 protein dimerization activity;GO:0003899 DNA-directed RNA polymerase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005665 RNA polymerase II, core complex", "go_biological_process": "GO:0006366 transcription by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter;GO:0006368 transcription elongation by RNA polymerase II;GO:0006369 termination of RNA polymerase II transcription;GO:0001172 RNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P38902-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38920-1", "uniprot_id": "MLH1_YEAST", "mass": 87062.0, "length": 769, "protein_name": "DNA mismatch repair protein MLH1", "gene_name": "MLH1", "organism": "Yeast", "refseq_name": "mismatch repair ATPase MLH1", "refseq_ac": "NP_013890", "gene_names_uniprotkb": "MLH1; PMS2; YM8520.16", "gene_names_refseq": "MLH1; PMS2", "protein_names_uniprotkb": "DNA mismatch repair protein MLH1; MutL protein homolog 1; Post meiotic segregation protein 2", "protein_names_refseq": "mismatch repair ATPase MLH1", "tax_id": 559292, "disease": "Muir-Torre syndrome (Disease Ontology:DOID:0050465); hereditary nonpolyposis colorectal cancer type 2 (Disease Ontology:DOID:0070274); mismatch repair cancer syndrome (Disease Ontology:DOID:0112182); urinary bladder cancer (Disease Ontology:DOID:11054); lung cancer (Disease Ontology:DOID:1324); colon cancer (Disease Ontology:DOID:219); laryngeal squamous cell carcinoma (Disease Ontology:DOID:2876); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); Lynch syndrome (Disease Ontology:DOID:3883); lung carcinoma (Disease Ontology:DOID:3905); lung non-small cell carcinoma (Disease Ontology:DOID:3908); renal cell carcinoma (Disease Ontology:DOID:4450); primary ovarian insufficiency (Disease Ontology:DOID:5426); malignant pleural mesothelioma (Disease Ontology:DOID:7474); sporadic breast cancer (Disease Ontology:DOID:8029); cervix uteri carcinoma in situ (Disease Ontology:DOID:8991); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (sce:YMR167W); (R-SCE-5358565)", "pathway_count": 2, "publication_count": 25, "publication_id_list": "10570173;10938116;11555625;11717305;12222686;12529393;12682353;14562095;14562106;16492773;17563356;18407956;19779198;19795423;19823750;22031224;23749301;24374639;32597660;33481703;33491328;8264608;9169872;9234704;9545323", "class_list": "", "function": "Required for DNA mismatch repair (MMR), correcting base-base mismatches and insertion-deletion loops (IDLs) resulting from DNA replication, DNA damage or from recombination events between non-identical sequences during meiosis. Component of different MutL heterodimers that form a ternary complex with the MutS heterodimers, which initially recognize the DNA mismatches. This complex is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. Plays a major role in maintaining the genetic stability of simple sequence repeats, the repair of heteroduplex sites present in meiotic recombination intermediates, and the promotion of meiotic crossing-over., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 31, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 17, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZY9;Q2I028;Q2I029;Q2I031;Q2I032;Q2I033;Q2I034;Q2I035;Q2I036;Q2I038;Q2I039;Q2I041", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0030983 mismatched DNA binding;GO:0140664 ATP-dependent DNA damage sensor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0032389 MutLalpha complex;GO:0097587 MutLgamma complex", "go_biological_process": "GO:0000710 meiotic mismatch repair;GO:0006298 mismatch repair;GO:0007131 reciprocal meiotic recombination;GO:0000713 meiotic heteroduplex formation", "synthesized_glycan_count": 0, "hit_score": 2.6, "record_id": "P38920-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38928-1", "uniprot_id": "AXL2_YEAST", "mass": 90783.0, "length": 823, "protein_name": "Axial budding pattern protein 2", "gene_name": "AXL2", "organism": "Yeast", "refseq_name": "Axl2p", "refseq_ac": "NP_012126", "gene_names_uniprotkb": "AXL2; BUD10; SRO4", "gene_names_refseq": "AXL2; BUD10; SRO4", "protein_names_uniprotkb": "Axial budding pattern protein 2; Bud site selection protein 10; Suppressor of RHO3 protein 4", "protein_names_refseq": "Axl2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL140W)", "pathway_count": 1, "publication_count": 30, "publication_id_list": "10366591;11065362;11134078;11313501;12221111;1448099;14562095;14562106;15282802;17330950;17460121;19779198;19795423;19823750;20702584;21177495;21725298;22218487;23749301;24374639;24909858;30516470;32597660;33481703;33491328;7871890;8805277;8846915;9169870;9732282", "class_list": "", "function": "Required for haploid cells axial budding pattern. Acts as an anchor to help direct new growth components and/or polarity establishment components like the BUD5 GTP/GDP exchange factor to localize at the cortical axial budding site. Regulates septin organization in late G1 independently of its role in polarity-axis determination., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 17, "predicted_n_glycosites": 16, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 32, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 17, "binding_glycan_count": 0, "secondary_ac_list": "D6VVE6;Q96VY8", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0032153 cell division site;GO:0000131 incipient cellular bud site;GO:0000144 cellular bud neck septin ring;GO:0000324 fungal-type vacuole", "go_biological_process": "GO:0007120 axial cellular bud site selection", "synthesized_glycan_count": 0, "hit_score": 3.1, "record_id": "P38928-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38930-1", "uniprot_id": "CSK2C_YEAST", "mass": 29842.0, "length": 258, "protein_name": "Casein kinase II subunit beta'", "gene_name": "CKB2", "organism": "Yeast", "refseq_name": "casein kinase 2 regulatory subunit CKB2", "refseq_ac": "NP_014682", "gene_names_uniprotkb": "CKB2; OR26.32", "gene_names_refseq": "CKB2", "protein_names_uniprotkb": "Casein kinase II subunit beta'; CK II beta'", "protein_names_refseq": "casein kinase 2 regulatory subunit CKB2", "tax_id": 559292, "disease": "leiomyoma (Disease Ontology:DOID:127); myocardial infarction (Disease Ontology:DOID:5844)", "pathway": " (sce:YOR039W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "12242279;14562106;17322287;21126336;22156209;24374639;32597660;33481703;33491328;8027080;8135547;9169874", "class_list": "", "function": "Regulatory subunit of casein kinase II/CK2 (By similarity). As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2A6", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0019887 protein kinase regulator activity;GO:0030291 protein serine/threonine kinase inhibitor activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005956 protein kinase CK2 complex;GO:0032040 small-subunit processome;GO:0032545 CURI complex", "go_biological_process": "GO:0006974 DNA damage response;GO:0051726 regulation of cell cycle;GO:0006359 regulation of transcription by RNA polymerase III;GO:0000028 ribosomal small subunit assembly;GO:0006356 regulation of transcription by RNA polymerase I", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P38930-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38953-1", "uniprot_id": "RAD55_YEAST", "mass": 46350.0, "length": 406, "protein_name": "DNA repair protein RAD55", "gene_name": "RAD55", "organism": "Yeast", "refseq_name": "putative DNA-dependent ATPase RAD55", "refseq_ac": "NP_010361", "gene_names_uniprotkb": "RAD55; D4426", "gene_names_refseq": "RAD55", "protein_names_uniprotkb": "DNA repair protein RAD55", "protein_names_refseq": "putative DNA-dependent ATPase RAD55", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR076W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "14562106;16793401;16966380;17322287;18407956;20061370;23749301;24374639;33491328;7483840;8181742;9169867", "class_list": "", "function": "Required for radiation resistance and meiotic viability and presumably acts in recombination and recombinational DNA repair pathways., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS62", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0008094 ATP-dependent activity, acting on DNA;GO:0140664 ATP-dependent DNA damage sensor activity", "go_cellular_component": "GO:0033065 Rad51C-XRCC3 complex;GO:0005657 replication fork;GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex", "go_biological_process": "GO:0000707 meiotic DNA recombinase assembly;GO:0006302 double-strand break repair;GO:0007131 reciprocal meiotic recombination;GO:0000730 DNA recombinase assembly;GO:0042275 error-free postreplication DNA repair", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P38953-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38956-1", "uniprot_id": "SNF11_YEAST", "mass": 18667.0, "length": 169, "protein_name": "Transcription regulatory protein SNF11", "gene_name": "SNF11", "organism": "Yeast", "refseq_name": "Snf11p", "refseq_ac": "NP_010358", "gene_names_uniprotkb": "SNF11; D4411", "gene_names_refseq": "SNF11", "protein_names_uniprotkb": "Transcription regulatory protein SNF11; SWI/SNF complex component SNF11", "protein_names_refseq": "Snf11p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR073W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "12524530;14562106;17322287;22814378;24374639;7623818;9169867", "class_list": "", "function": "Involved in transcriptional activation. Component of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS59", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0016514 SWI/SNF complex;GO:0000785 chromatin", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P38956-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38959-1", "uniprot_id": "VPS41_YEAST", "mass": 113412.0, "length": 992, "protein_name": "Vacuolar protein sorting-associated protein 41", "gene_name": "VPS41", "organism": "Yeast", "refseq_name": "Vps41p", "refseq_ac": "NP_010365", "gene_names_uniprotkb": "VPS41; D446; FET2; VAM2; YD8554.13", "gene_names_refseq": "CVT8; FET2; SVL2; VAM2; VPL20; VPS41", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 41; Vacuolar morphogenesis protein 2", "protein_names_refseq": "Vps41p", "tax_id": 559292, "disease": "autosomal recessive spinocerebellar ataxia 29 (Disease Ontology:DOID:0070410); Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (sce:YDR080W)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "14562106;16601699;17330950;17563356;18407956;19193765;19779198;21079247;21126336;22218487;23749301;24374639;32597660;33481703;33491328;7483840;9111041;9159129;9169867", "class_list": "", "function": "Required for vacuolar assembly and vacuolar traffic. Acts as component of the HOPS complex that acts during the docking stage of vacuole fusion. HOPS is an effector for the vacuolar Rab GTPase YPT7 and is required for vacuolar SNARE complex assembly. It remains bound to SNARE complexes after vacuole fusion., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 24, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS67;P87334;Q12011", "ec_number_list": "", "go_molecular_function": "GO:0031267 small GTPase binding;GO:0043495 protein-membrane adaptor activity", "go_cellular_component": "GO:0030897 HOPS complex;GO:0005768 endosome;GO:0005770 late endosome;GO:0005774 vacuolar membrane;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0007034 vacuolar transport;GO:0035542 regulation of SNARE complex assembly;GO:0042144 vacuole fusion, non-autophagic;GO:0015031 protein transport;GO:0016236 macroautophagy", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P38959-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38968-1", "uniprot_id": "SEC31_YEAST", "mass": 138717.0, "length": 1273, "protein_name": "Protein transport protein SEC31", "gene_name": "SEC31", "organism": "Yeast", "refseq_name": "Sec31p", "refseq_ac": "NP_010086", "gene_names_uniprotkb": "SEC31; D1229; WEB1", "gene_names_refseq": "SEC31; WEB1", "protein_names_uniprotkb": "Protein transport protein SEC31; Protein WEB1", "protein_names_refseq": "Sec31p", "tax_id": 559292, "disease": "Halperin-Birk syndrome (Disease Ontology:DOID:0070539)", "pathway": " (sce:YDL195W); (R-SCE-204005)", "pathway_count": 2, "publication_count": 43, "publication_id_list": "10564255;10720463;11389436;11535824;11560939;11717432;11875433;12235121;12671686;14562095;14562106;14627716;15665377;17330950;17563356;17604721;17981133;18407956;19684113;19779198;19795423;19823750;20696705;20702584;21126336;21177495;22218487;22814378;23749301;24374639;32597660;33229814;33481703;33491328;7760818;8548805;8852839;8896272;9023343;9169867;9190202;9325247;9568718", "class_list": "", "function": "Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 16, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 16, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 16, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 46, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 16, "binding_glycan_count": 0, "secondary_ac_list": "D6VRF8", "ec_number_list": "", "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0070971 endoplasmic reticulum exit site;GO:0030127 COPII vesicle coat;GO:0043332 mating projection tip", "go_biological_process": "GO:0090110 COPII-coated vesicle cargo loading;GO:0015031 protein transport;GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport;GO:0070863 positive regulation of protein exit from endoplasmic reticulum;GO:0007029 endoplasmic reticulum organization", "synthesized_glycan_count": 0, "hit_score": 6.1, "record_id": "P38968-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38987-1", "uniprot_id": "TEM1_YEAST", "mass": 27296.0, "length": 245, "protein_name": "Protein TEM1", "gene_name": "TEM1", "organism": "Yeast", "refseq_name": "Ras family GTPase TEM1", "refseq_ac": "NP_013647", "gene_names_uniprotkb": "TEM1", "gene_names_refseq": "TEM1", "protein_names_uniprotkb": "Protein TEM1", "protein_names_refseq": "Ras family GTPase TEM1", "tax_id": 559292, "disease": "", "pathway": " (sce:YML064C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "12628189;14562106;17322287;19684113;19779198;21126336;21177495;23749301;24374639;32597660;33491328;7935462;9169872", "class_list": "", "function": "GTP-binding protein involved in termination of M phase. May play a role in triggering the degradation of G2 cyclin to inactivate M-phase promoting factor at the termination of mitosis. Acts upstream of CDC15 kinase and may be required to activate the CDC15 protein kinase pathway., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VZA9", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0005816 spindle pole body", "go_biological_process": "GO:1904750 negative regulation of protein localization to nucleolus;GO:0051301 cell division;GO:0031536 positive regulation of exit from mitosis;GO:0040001 establishment of mitotic spindle localization;GO:0023056 positive regulation of signaling", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P38987-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P39001-1", "uniprot_id": "UME6_YEAST", "mass": 91124.0, "length": 836, "protein_name": "Transcriptional regulatory protein UME6", "gene_name": "UME6", "organism": "Yeast", "refseq_name": "DNA-binding transcriptional regulator UME6", "refseq_ac": "NP_010493", "gene_names_uniprotkb": "UME6; CAR80; CARGR1; NIM2; RIM16; YD8142.04C", "gene_names_refseq": "CAR80; NIM2; RIM16; UME6", "protein_names_uniprotkb": "Transcriptional regulatory protein UME6; Negative transcriptional regulator of IME2; Regulator of inducer of meiosis protein 16; Unscheduled meiotic gene expression protein 6", "protein_names_refseq": "DNA-binding transcriptional regulator UME6", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR207C)", "pathway_count": 1, "publication_count": 43, "publication_id_list": "10891485;10931932;11081629;11238941;12370439;12693549;12799429;14562095;14562106;1579492;15837806;1592244;16314178;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;21177495;23749301;24374639;2690066;30516470;32597660;33229814;33481703;33491328;33502312;7760793;7926768;8528081;8614637;8618927;8628320;9150136;9169867;9343383;9372955;9572144;9710596", "class_list": "", "function": "Component of the RPD3C(L) histone deacetylase complex (HDAC) responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Binds to the URS1 site (5'-AGCCGCCGA-3') and recruits the RPD3 histone deacetylase complex to the promoters to negatively regulate the expression of many genes including CAR1 (arginase), several required for sporulation, mating type switching, inositol metabolism, and oxidative carbon metabolism. Also recruits the ISW2 chromatin remodeling complex to promoters in a second gene repression pathway. Associates with the master regulator of meiosis IME1 in order to activate the expression of meiosis genes. Has both a positive and negative role in regulating phospholipid biosynthesis., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 5, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 5, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 5, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 49, "reported_mutagensis": 15, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "D6VSI8", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0043565 sequence-specific DNA binding;GO:0140297 DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0070210 Rpd3L-Expanded complex;GO:0033698 Rpd3L complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0000278 mitotic cell cycle;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 5.0, "record_id": "P39001-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P39008-1", "uniprot_id": "POP2_YEAST", "mass": 49682.0, "length": 433, "protein_name": "Poly(A) ribonuclease POP2", "gene_name": "POP2", "organism": "Yeast", "refseq_name": "CCR4-NOT core DEDD family RNase subunit POP2", "refseq_ac": "NP_014450", "gene_names_uniprotkb": "POP2; CAF1; N3470", "gene_names_refseq": "CAF1; POP2", "protein_names_uniprotkb": "Poly(A) ribonuclease POP2; 3.1.13.4; CCR4-associated factor 1", "protein_names_refseq": "CCR4-NOT core DEDD family RNase subunit POP2", "tax_id": 559292, "disease": "heart disease (Disease Ontology:DOID:114); male infertility (Disease Ontology:DOID:12336)", "pathway": " (sce:YNR052C)", "pathway_count": 1, "publication_count": 26, "publication_id_list": "10490603;11239395;11358866;11410650;11733989;14562106;14618157;1475183;17322287;18407956;19684113;19779198;20386698;20702584;21177495;22218487;22814378;23749301;24374639;30973945;32597660;33481703;33491328;7791755;9169873;9463387", "class_list": "", "function": "Acts as a probably catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. In vitro, POP2 has 3'-exoribonuclease activity with a preference for poly(A) RNAs, but also degrades poly(U) and poly(C) RNAs. Is part of a glucose-sensing system involved in growth control in response to glucose availability., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1M7", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0046872 metal ion binding;GO:0000175 3'-5'-RNA exonuclease activity;GO:0004535 poly(A)-specific ribonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000932 P-body;GO:0030015 CCR4-NOT core complex;GO:0043332 mating projection tip", "go_biological_process": "GO:0006368 transcription elongation by RNA polymerase II;GO:0032968 positive regulation of transcription elongation by RNA polymerase II;GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening", "synthesized_glycan_count": 0, "hit_score": 2.7, "record_id": "P39008-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P39010-1", "uniprot_id": "AKR1_YEAST", "mass": 85840.0, "length": 764, "protein_name": "Palmitoyltransferase AKR1", "gene_name": "AKR1", "organism": "Yeast", "refseq_name": "palmitoyltransferase AKR1", "refseq_ac": "NP_010550", "gene_names_uniprotkb": "AKR1; D9954.9; YD9230B.03C", "gene_names_refseq": "AKR1", "protein_names_uniprotkb": "Palmitoyltransferase AKR1; 2.3.1.225; Ankyrin repeat-containing protein AKR1", "protein_names_refseq": "palmitoyltransferase AKR1", "tax_id": 559292, "disease": "Huntington's disease (Disease Ontology:DOID:12858)", "pathway": " (sce:YDR264C)", "pathway_count": 1, "publication_count": 26, "publication_id_list": "10866691;12370247;14562095;14562106;15105419;15632165;16847258;17287358;17330950;17563356;18407956;19684113;19779198;20702584;21126336;21177495;22814378;23749301;24374639;30516470;32597660;33481703;33491328;8524293;9169867;9243510", "class_list": "", "function": "Palmitoyltransferase specific for casein kinase 1. Palmitoylates isoforms YCK1 and YCK2 at both C-terminal cysteine residues, which is required for their proper plasma membrane localization. Required for constitutive endocytosis of a-factor receptor STE3 and both constitutive and pheromone-induced endocytosis of alpha-factor receptor STE2., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSP8", "ec_number_list": "2.3.1.225", "go_molecular_function": "GO:0031683 G-protein beta/gamma-subunit complex binding;GO:0019706 protein-cysteine S-palmitoyltransferase activity;GO:0016409 palmitoyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0031901 early endosome membrane", "go_biological_process": "GO:0030100 regulation of endocytosis;GO:0006612 protein targeting to membrane;GO:0018345 protein palmitoylation;GO:0090029 negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion", "synthesized_glycan_count": 0, "hit_score": 2.7, "record_id": "P39010-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P39081-1", "uniprot_id": "PCF11_YEAST", "mass": 71898.0, "length": 626, "protein_name": "Protein PCF11", "gene_name": "PCF11", "organism": "Yeast", "refseq_name": "Pcf11p", "refseq_ac": "NP_010514", "gene_names_uniprotkb": "PCF11; YD9934.13C", "gene_names_refseq": "PCF11", "protein_names_uniprotkb": "Protein PCF11; protein 1 of CF I", "protein_names_refseq": "Pcf11p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR228C); (R-SCE-9770562)", "pathway_count": 2, "publication_count": 15, "publication_id_list": "11149954;11344258;12727883;14562106;15241417;15565157;15665873;15998810;23749301;24374639;33481703;33491328;7885847;9032237;9169867", "class_list": "", "function": "Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factor NAB4/CFIB and the cleavage and polyadenylation factor (CPF) complex. Independently involved in RNA polymerase II transcript termination. Binds RNA. Seems to bridge RNA polymerase II and the native transcript and may be involved in dismantling the RNA polymerase II elongation complex., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VSL0;Q04932", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0000993 RNA polymerase II complex binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005849 mRNA cleavage factor complex", "go_biological_process": "GO:0006369 termination of RNA polymerase II transcription;GO:0031124 mRNA 3'-end processing;GO:0030846 termination of RNA polymerase II transcription, poly(A)-coupled;GO:0030847 termination of RNA polymerase II transcription, exosome-dependent", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P39081-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P39107-1", "uniprot_id": "MNN9_YEAST", "mass": 45955.0, "length": 395, "protein_name": "Mannan polymerase complexes subunit MNN9", "gene_name": "MNN9", "organism": "Yeast", "refseq_name": "mannosyltransferase complex subunit MNN9", "refseq_ac": "NP_015275", "gene_names_uniprotkb": "MNN9; P7102.01", "gene_names_refseq": "MNN9", "protein_names_uniprotkb": "Mannan polymerase complexes subunit MNN9; M-Pol II subunit MNN9; M-pol I subunit MNN9", "protein_names_refseq": "mannosyltransferase complex subunit MNN9", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL050C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "11095735;12235155;14562106;22814378;24374639;7818498;8146181;9169875;9430634;9434768", "class_list": "", "function": "The M-Pol I and M-Pol II complexes possess alpha-1,6-mannosyltransferase activity and are probably involved in the elongation of the mannan backbone of N-linked glycans on cell wall and periplasmic proteins. May also provide alpha-1,2-mannosyltransferase activity to the M-Pol I complex., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 1, "mined_n_glycosites": 1, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W3W4", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0005801 cis-Golgi network;GO:0000137 Golgi cis cisterna;GO:0000136 mannan polymerase complex", "go_biological_process": "GO:0000032 cell wall mannoprotein biosynthetic process;GO:0006487 protein N-linked glycosylation", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P39107-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P39108-1", "uniprot_id": "PEX7_YEAST", "mass": 42323.0, "length": 375, "protein_name": "Peroxisomal targeting signal 2 receptor", "gene_name": "PEX7", "organism": "Yeast", "refseq_name": "Pex7p", "refseq_ac": "NP_010426", "gene_names_uniprotkb": "PEX7; PAS7; PEB1; YD2943.01C; YD9302.18C", "gene_names_refseq": "PAS7; PEB1; PEX7", "protein_names_uniprotkb": "Peroxisomal targeting signal 2 receptor; PTS2 receptor; Peroxin-7", "protein_names_refseq": "Pex7p", "tax_id": 559292, "disease": "Peroxisome biogenesis disorder 9B (Disease Ontology:DOID:0081438); rhizomelic chondrodysplasia punctata type 1 (Disease Ontology:DOID:0110851)", "pathway": " (sce:YDR142C); (R-SCE-9033241)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "14562106;14690591;17322287;23812376;24374639;40739340;7535304;7957058;9094717;9169867;9864360", "class_list": "", "function": "Receptor required for the peroxisomal import of proteins containing an N-terminal PTS2-type peroxisomal targeting signal, such as 3-oxoacyl-CoA thiolase (PubMed:23812376, PubMed:7535304, PubMed:7957058). Specifically binds to cargo proteins containing a PTS2 peroxisomal targeting signal in the cytosol (PubMed:23812376). Cargo protein-binding triggers interaction with PEX21 or PEX18 and formation of a ternary complex composed of PEX21 or PEX18 and PEX7 along with PTS2-containing cargo proteins, which is translocated into peroxisomes by passing through the PEX13-PEX14 docking complex (PubMed:23812376, PubMed:9094717, PubMed:9864360)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSC5", "ec_number_list": "", "go_molecular_function": "GO:0005053 peroxisome matrix targeting signal-2 binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005777 peroxisome;GO:0005778 peroxisomal membrane;GO:0005782 peroxisomal matrix;GO:0005829 cytosol", "go_biological_process": "GO:0016558 protein import into peroxisome matrix;GO:0016560 protein import into peroxisome matrix, docking", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P39108-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P39517-1", "uniprot_id": "DHH1_YEAST", "mass": 57544.0, "length": 506, "protein_name": "ATP-dependent RNA helicase DHH1", "gene_name": "DHH1", "organism": "Yeast", "refseq_name": "DExD/H-box ATP-dependent RNA helicase DHH1", "refseq_ac": "NP_010121", "gene_names_uniprotkb": "DHH1", "gene_names_refseq": "DHH1", "protein_names_uniprotkb": "ATP-dependent RNA helicase DHH1; 3.6.4.13; DExD/H-box helicase 1", "protein_names_refseq": "DExD/H-box ATP-dependent RNA helicase DHH1", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL160C); (R-SCE-430039)", "pathway_count": 2, "publication_count": 30, "publication_id_list": "11696541;11780629;12032091;12730603;12930949;14562095;14562106;15166134;15703442;15706350;15987810;18407956;19795423;19823750;20471941;20702584;22218487;24374639;24909858;26098573;30516470;31323064;32597660;32989641;33481703;33491328;35835957;8511971;9169867;9504907", "class_list": "", "function": "ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping by activating the decapping enzyme DCP1 (PubMed:11696541, PubMed:11780629, PubMed:12032091, PubMed:12730603, PubMed:15703442, PubMed:15706350). Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs (PubMed:15166134). May also have a role in translation and mRNA nuclear export (PubMed:12930949). Required for sporulation (PubMed:12930949). Blocks autophagy in nutrient-rich conditions by, at least partly, binding and repressing the expression of a set of ATG genes, including ATG3, ATG7, ATG8, ATG19, ATG20, ATG22 and SNX4/ATG24 (PubMed:26098573)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 8, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRJ0", "ec_number_list": "3.6.4.13;5.6.2.3;3.6.4.10;3.6.-.-;5.6.2.4;3.6.4.-;5.6.1.4;3.6.4.12;3.6.4.6;5.6.2.5;3.6.1.-;2.3.2.27;3.1.-.-;3.4.24.-;3.6.5.-;3.6.1.62;2.7.4.3;2.7.11.1;7.2.2.-", "go_molecular_function": "GO:0003682 chromatin binding;GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0000932 P-body;GO:0010494 cytoplasmic stress granule;GO:0098562 cytoplasmic side of membrane", "go_biological_process": "GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0006397 mRNA processing;GO:0042149 cellular response to glucose starvation;GO:0017148 negative regulation of translation;GO:0045727 positive regulation of translation", "synthesized_glycan_count": 0, "hit_score": 3.1, "record_id": "P39517-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P39524-1", "uniprot_id": "ATC3_YEAST", "mass": 153765.0, "length": 1355, "protein_name": "Phospholipid-transporting ATPase DRS2", "gene_name": "DRS2", "organism": "Yeast", "refseq_name": "aminophospholipid-translocating P4-type ATPase DRS2", "refseq_ac": "NP_009376", "gene_names_uniprotkb": "DRS2; FUN38; SWA3", "gene_names_refseq": "DRS2; FUN38; SWA3", "protein_names_uniprotkb": "Phospholipid-transporting ATPase DRS2; 7.6.2.1", "protein_names_refseq": "aminophospholipid-translocating P4-type ATPase DRS2", "tax_id": 559292, "disease": "cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome (Disease Ontology:DOID:0050997); cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome 4 (Disease Ontology:DOID:0070559)", "pathway": " (sce:YAL026C); (R-SCE-6798695); (R-SCE-936837)", "pathway_count": 3, "publication_count": 38, "publication_id_list": "10601336;12372257;12631737;14562095;14562106;14734650;15090616;15249668;15665377;16452632;16847258;16956384;17330950;18407956;19411703;19684113;19779198;19805341;19898464;20702584;21212072;22308393;22791719;23302692;23749301;24045945;24374639;25393116;27235400;28302728;30824614;31243363;31515475;33481703;33491328;34023399;7731988;8247005", "class_list": "", "function": "Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of phosphatidylserine and small amounts of ethanolamine from the lumen to the cytosolic leaflet of the trans-Golgi network and ensures the maintenance of asymmetric distribution of phospholipids (PubMed:15249668, PubMed:16452632, PubMed:16956384, PubMed:19411703, PubMed:19805341, PubMed:19898464, PubMed:22308393, PubMed:24045945, PubMed:25393116, PubMed:28302728, PubMed:30824614, PubMed:31243363, PubMed:31515475, PubMed:34023399). Contributes to clathrin-coated vesicle formation, endocytosis, and protein trafficking between the Golgi and endosomal system (PubMed:10601336, PubMed:12372257, PubMed:15249668, PubMed:16452632, PubMed:16956384, PubMed:21212072, PubMed:8247005). Does not appear to transport phosphatidylcholine or sphingomyelin (PubMed:15249668, PubMed:19805341, PubMed:24045945)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 21, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VPJ2", "ec_number_list": "3.6.5.2;3.1.3.48;7.6.2.1;2.3.1.51;2.3.1.23;2.3.1.n7;3.1.4.4;1.2.1.3;1.2.1.64", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0090555 phosphatidylethanolamine flippase activity;GO:0090556 phosphatidylserine floppase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0010008 endosome membrane;GO:0005802 trans-Golgi network;GO:1990530 Cdc50p-Drs2p complex", "go_biological_process": "GO:0006897 endocytosis;GO:0045332 phospholipid translocation;GO:0006892 post-Golgi vesicle-mediated transport;GO:0032456 endocytic recycling", "synthesized_glycan_count": 0, "hit_score": 3.9, "record_id": "P39524-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P39742-1", "uniprot_id": "SEC72_YEAST", "mass": 21607.0, "length": 193, "protein_name": "Translocation protein SEC72", "gene_name": "SEC72", "organism": "Yeast", "refseq_name": "Sec63 complex subunit SEC72", "refseq_ac": "NP_013395", "gene_names_uniprotkb": "SEC72; L8003.18; SEC67; SIM2", "gene_names_refseq": "SEC67; SEC72; SIM2", "protein_names_uniprotkb": "Translocation protein SEC72; Sec62/63 complex 23 kDa subunit; p23", "protein_names_refseq": "Sec63 complex subunit SEC72", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR292C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "12518317;14562106;17322287;2000150;24374639;7758110;8051213;8253836;8441423;8455603;9169871", "class_list": "", "function": "Acts as a non-essential component of the Sec62/63 complex which is involved in SRP-independent post-translational translocation across the endoplasmic reticulum (ER) and functions together with the Sec61 complex and KAR2 in a channel-forming translocon complex. A cycle of assembly and disassembly of Sec62/63 complex from SEC61 may govern the activity of the translocon. SEC72 may be involved in signal peptide recognition for a defined subset of leader peptides, or may increase the efficiency of unusual or 'difficult' secretory precursors to the translocation pore, it may be that this protein binds charged leader peptides to the membrane until they engage the translocation apparatus., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYT8", "ec_number_list": "", "go_molecular_function": "GO:0008320 protein transmembrane transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0030867 rough endoplasmic reticulum membrane;GO:0031207 Sec62/Sec63 complex", "go_biological_process": "GO:0031204 post-translational protein targeting to membrane, translocation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P39742-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P39743-1", "uniprot_id": "RV167_YEAST", "mass": 52774.0, "length": 482, "protein_name": "Reduced viability upon starvation protein 167", "gene_name": "RVS167", "organism": "Yeast", "refseq_name": "amphiphysin", "refseq_ac": "NP_010676", "gene_names_uniprotkb": "RVS167; D9509.8", "gene_names_refseq": "RVS167", "protein_names_uniprotkb": "Reduced viability upon starvation protein 167", "protein_names_refseq": "amphiphysin", "tax_id": 559292, "disease": "centronuclear myopathy 2 (Disease Ontology:DOID:0111220)", "pathway": " (sce:YDR388W)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "10388809;12857883;12872131;14562106;15561700;15665377;15802519;18407956;21126336;22106047;22814378;23749301;24374639;32597660;33481703;33491328;7719850;8336735;9169867;9843683", "class_list": "", "function": "Component of a cytoskeletal structure that is required for the formation of endocytic vesicles at the plasma membrane level. Could be implicated in cytoskeletal reorganization in response to environmental stresses and could act in the budding site selection mechanism., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 21, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VT22", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0005516 calmodulin binding;GO:0042802 identical protein binding;GO:0008092 cytoskeletal protein binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0015629 actin cytoskeleton;GO:0030479 actin cortical patch;GO:0005934 cellular bud tip", "go_biological_process": "GO:0006897 endocytosis;GO:0030100 regulation of endocytosis;GO:0016192 vesicle-mediated transport;GO:0051666 actin cortical patch localization;GO:0060988 lipid tube assembly", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P39743-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P39960-1", "uniprot_id": "BEM2_YEAST", "mass": 245430.0, "length": 2167, "protein_name": "GTPase-activating protein BEM2/IPL2", "gene_name": "BEM2", "organism": "Yeast", "refseq_name": "GTPase-activating protein BEM2", "refseq_ac": "NP_011082", "gene_names_uniprotkb": "BEM2; IPL2; SUP9", "gene_names_refseq": "BEM2; IPL2; SUP9; TSL1", "protein_names_uniprotkb": "GTPase-activating protein BEM2/IPL2; Bud emergence protein 2", "protein_names_refseq": "GTPase-activating protein BEM2", "tax_id": 559292, "disease": "Duane retraction syndrome 2 (Disease Ontology:DOID:0061028); Duane retraction syndrome (Disease Ontology:DOID:12557)", "pathway": " (sce:YER155C); (R-SCE-6798695); (R-SCE-8980692); (R-SCE-9013148); (R-SCE-9013149); (R-SCE-9013423); (R-SCE-9013424); (R-SCE-9035034)", "pathway_count": 8, "publication_count": 24, "publication_id_list": "14562106;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20489023;20702584;21126336;22106047;23749301;24374639;24909858;32597660;33229814;33481703;33491328;7962097;7962098;8293973;9169868", "class_list": "", "function": "GTPase-activating protein (GAP) for RHO1 and RHO2. Involved in the control of cellular morphogenesis. Required for proper bud site selection and bud emergence., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 47, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 47, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 47, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 93, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 2, "glyco_site_count": 46, "binding_glycan_count": 0, "secondary_ac_list": "D3DM62", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0005096 GTPase activator activity;GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0051286 cell tip;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005886 plasma membrane;GO:0005938 cell cortex", "go_biological_process": "GO:0030036 actin cytoskeleton organization;GO:0007264 small GTPase-mediated signal transduction;GO:0035024 negative regulation of Rho protein signal transduction;GO:0044879 mitotic morphogenesis checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 7.3, "record_id": "P39960-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P39968-1", "uniprot_id": "VAC8_YEAST", "mass": 63208.0, "length": 578, "protein_name": "Vacuolar protein 8", "gene_name": "VAC8", "organism": "Yeast", "refseq_name": "protein anchor VAC8", "refseq_ac": "NP_010903", "gene_names_uniprotkb": "VAC8; YEB3", "gene_names_refseq": "VAC8; YEB3", "protein_names_uniprotkb": "Vacuolar protein 8", "protein_names_refseq": "protein anchor VAC8", "tax_id": 559292, "disease": "", "pathway": " (sce:YEL013W)", "pathway_count": 1, "publication_count": 25, "publication_id_list": "10837477;10888680;11406591;12529432;14562106;16186255;16912077;17330950;18407956;19779198;20702584;21126336;21177495;22106047;22218487;23749301;24374639;28533415;31512555;32597660;33481703;33491328;34965436;9169868;9490720", "class_list": "", "function": "Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole (cvt) (PubMed:9490720). Involved in the formation of nucleus-vacuole junctions (NVJs) during piecemeal microautophagy of the nucleus (PMN) (PubMed:10888680, PubMed:12529432, PubMed:16912077). NVJs are interorganelle interfaces mediated by NVJ1 in the nuclear envelope and VAC8 on the vacuole membrane (PubMed:10888680, PubMed:12529432, PubMed:16912077). Together, NVJ1 and VAC8 form Velcro-like patches through which teardrop-like portions of the nucleus are pinched off into the vacuolar lumen and degraded by the PMN process (PubMed:10888680, PubMed:12529432, PubMed:16912077)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLN6;Q549T0", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0043495 protein-membrane adaptor activity", "go_cellular_component": "GO:0071561 nucleus-vacuole junction;GO:0005829 cytosol;GO:0016020 membrane;GO:0031965 nuclear membrane;GO:0045121 membrane raft", "go_biological_process": "GO:0042144 vacuole fusion, non-autophagic;GO:0000045 autophagosome assembly;GO:0006629 lipid metabolic process;GO:0016236 macroautophagy;GO:0006914 autophagy", "synthesized_glycan_count": 0, "hit_score": 2.6, "record_id": "P39968-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P39990-1", "uniprot_id": "SNU13_YEAST", "mass": 13569.0, "length": 126, "protein_name": "13 kDa ribonucleoprotein-associated protein", "gene_name": "SNU13", "organism": "Yeast", "refseq_name": "RNA binding protein SNU13", "refseq_ac": "NP_010888", "gene_names_uniprotkb": "SNU13", "gene_names_refseq": "SNU13", "protein_names_uniprotkb": "13 kDa ribonucleoprotein-associated protein; Small nuclear ribonucleoprotein-associated protein 1", "protein_names_refseq": "RNA binding protein SNU13", "tax_id": 559292, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (sce:YEL026W); (R-SCE-6791226)", "pathway_count": 2, "publication_count": 15, "publication_id_list": "10377396;10449419;11081632;11804584;12068309;12215523;12810916;14690591;14730029;15963469;17322287;24374639;33481703;33491328;9169868", "class_list": "", "function": "Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for splicing of pre-mRNA. In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs. Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DLM2", "ec_number_list": "", "go_molecular_function": "GO:0030621 U4 snRNA binding;GO:0003723 RNA binding;GO:0034511 U3 snoRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0071011 precatalytic spliceosome;GO:0031428 box C/D methylation guide snoRNP complex", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0000245 spliceosomal complex assembly;GO:0000494 box C/D sno(s)RNA 3'-end processing;GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0030490 maturation of SSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P39990-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40038-1", "uniprot_id": "PCL6_YEAST", "mass": 47007.0, "length": 420, "protein_name": "PHO85 cyclin-6", "gene_name": "PCL6", "organism": "Yeast", "refseq_name": "Pcl6p", "refseq_ac": "NP_010980", "gene_names_uniprotkb": "PCL6", "gene_names_refseq": "PCL6", "protein_names_uniprotkb": "PHO85 cyclin-6", "protein_names_refseq": "Pcl6p", "tax_id": 559292, "disease": "", "pathway": " (sce:YER059W)", "pathway_count": 1, "publication_count": 25, "publication_id_list": "10760578;11069666;11602261;11864988;12098764;12407105;14562095;14562106;15721288;17563356;18407956;19779198;19795423;20489023;20702584;21126336;21177495;23749301;24374639;32597660;33229814;33481703;33491328;9032248;9169868", "class_list": "", "function": "Cyclin partner of the cyclin-dependent kinase (CDK) PHO85. Together with cyclin PCL7, controls glycogen phosphorylase and glycogen synthase activities in response to nutrient availablility. The PCL6-PHO85 cyclin-CDK holoenzyme has GLC8 kinase activity and phosphorylates and inactivates the phosphatase PP1-2 inhibitor GLC8, causing activation of PP1-2, which then dephosphorylates and activates glycogen phosphorylase. PCL6-PHO85 also phosphorylates YJL084C., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 24, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D3DLW3", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding;GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000307 cyclin-dependent protein kinase holoenzyme complex", "go_biological_process": "GO:0005981 regulation of glycogen catabolic process;GO:0005977 glycogen metabolic process;GO:0005979 regulation of glycogen biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 3.0, "record_id": "P40038-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40065-1", "uniprot_id": "MAM1_YEAST", "mass": 35753.0, "length": 302, "protein_name": "Monopolin complex subunit MAM1", "gene_name": "MAM1", "organism": "Yeast", "refseq_name": "Mam1p", "refseq_ac": "NP_011032", "gene_names_uniprotkb": "MAM1", "gene_names_refseq": "MAM1", "protein_names_uniprotkb": "Monopolin complex subunit MAM1; Monopolar microtubule attachment during meiosis 1 protein 1", "protein_names_refseq": "Mam1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YER106W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "11163190;11470404;12586695;12663816;12689592;12717442;15226378;15620645;17322287;24374639;33502312;9169868", "class_list": "", "function": "Component of the monopolin complex which promotes monoorientation during meiosis I, required for chromosome segregation during meiosis., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DM13;E9P8Y3", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0000776 kinetochore;GO:0033551 monopolin complex", "go_biological_process": "GO:0051455 spindle attachment to meiosis I kinetochore;GO:0045143 homologous chromosome segregation;GO:0010789 meiotic sister chromatid cohesion involved in meiosis I;GO:0045132 meiotic chromosome segregation", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P40065-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40070-1", "uniprot_id": "LSM4_YEAST", "mass": 21276.0, "length": 187, "protein_name": "LSM complex subunit LSM4", "gene_name": "LSM4", "organism": "Yeast", "refseq_name": "U6 snRNA complex subunit LSM4", "refseq_ac": "NP_011037", "gene_names_uniprotkb": "LSM4; SDB23; USS1", "gene_names_refseq": "LSM4; SDB23; USS1", "protein_names_uniprotkb": "LSM complex subunit LSM4; Like-SM protein 4", "protein_names_refseq": "U6 snRNA complex subunit LSM4", "tax_id": 559292, "disease": "cancer (Disease Ontology:DOID:162); atherosclerosis (Disease Ontology:DOID:1936)", "pathway": " (sce:YER112W); (R-SCE-430039)", "pathway_count": 2, "publication_count": 24, "publication_id_list": "10369684;10428970;10449419;10747033;10761922;12077351;12438310;14562095;14562106;15075370;15485930;18407956;24139796;24240276;24374639;24513854;26046779;29717126;30059503;33491328;33856219;7744012;8497280;9169868", "class_list": "", "function": "Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner (PubMed:10747033, PubMed:12077351, PubMed:12438310, PubMed:24513854). Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation by activating the decapping step (PubMed:10747033, PubMed:10761922, PubMed:24513854). Together with PAT1, the LSM1-LSM7 complex binds to osmotic stress-activated mRNAs to attenuate the osmotic stress response, probably by limiting ribosome access to the mRNA and consequently translation (PubMed:30059503). Component of the nuclear LSM2-LSM8 complex, which is involved in spliceosome assembly (PubMed:10747033, PubMed:12077351, PubMed:12438310). The LSM2-LSM8 complex plays a role in the biogenesis of the spliceosomal U4/U6-U5 tri-snRNP complex by accelerating PRP24-mediated annealing of U4/U6 di-snRNA (PubMed:10747033, PubMed:24240276, PubMed:29717126). The LSM2-LSM8 complex binds U6 snRNA terminating with a non-cyclic 3' phosphate group (PubMed:29717126). LSM2-LSM8 is probably also involved in degradation of nuclear pre-mRNA by targeting them for decapping (PubMed:15485930). LSM2-LSM8 could be involved in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA, although involvement may be indirect (PubMed:12077351, PubMed:12438310, PubMed:15075370). In a complex that probably contains LSM2-LSM7, but not LSM1 or LSM8, associates with the precursor of the RNA component of RNase P (pre-P RNA) and may be involved in maturing pre-P RNA; the complex also associates with snoRNA SNR5 (PubMed:10369684, PubMed:15075370)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DM18;Q07091", "ec_number_list": "", "go_molecular_function": "GO:0017070 U6 snRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005681 spliceosomal complex;GO:0000932 P-body", "go_biological_process": "GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0008033 tRNA processing;GO:0042149 cellular response to glucose starvation;GO:0000387 spliceosomal snRNP assembly;GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "P40070-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40075-1", "uniprot_id": "SCS2_YEAST", "mass": 26926.0, "length": 244, "protein_name": "Vesicle-associated membrane protein-associated protein SCS2", "gene_name": "SCS2", "organism": "Yeast", "refseq_name": "phosphatidylinositol-binding protein SCS2", "refseq_ac": "NP_011046", "gene_names_uniprotkb": "SCS2", "gene_names_refseq": "SCS2", "protein_names_uniprotkb": "Vesicle-associated membrane protein-associated protein SCS2; Choline sensitivity suppressor protein 2; VAMP-associated protein SCS2; VAP homolog 1", "protein_names_refseq": "phosphatidylinositol-binding protein SCS2", "tax_id": 559292, "disease": "amyotrophic lateral sclerosis type 8 (Disease Ontology:DOID:0050752); autosomal dominant adult-onset proximal spinal muscular atrophy (Disease Ontology:DOID:0111194); spinal muscular atrophy (Disease Ontology:DOID:12377); neurodegenerative disease (Disease Ontology:DOID:1289); motor neuron disease (Disease Ontology:DOID:231); amyotrophic lateral sclerosis (Disease Ontology:DOID:332)", "pathway": " (sce:YER120W); (R-SCE-6798695); (R-SCE-9013106); (R-SCE-9609523)", "pathway_count": 4, "publication_count": 27, "publication_id_list": "12727870;14562095;14562106;15455074;15665377;15668246;16004875;17322287;17563356;19779198;19795423;19823750;21126336;21177495;22218487;23237950;23749301;24366873;24374639;25083872;32597660;33481703;33491328;34965436;8537323;9169868;9537365", "class_list": "", "function": "Acts as an endoplasmic reticulum (ER) membrane anchor for cytoplasmic proteins via binding to the FFAT motif of targeted proteins (PubMed:12727870, PubMed:15668246, PubMed:25083872). Regulates phospholipid biosynthesis by modulating the subcellular localization of the transcriptional repressor OPI1 (PubMed:12727870). Also contributes to the tethering of the ER to the plasma membrane (PubMed:23237950). Allows interorganelle phosphatidylserine (PtdSer) transport via a process that involves the acceptor membrane complex PDR17-PDS2 that binds to PBI1 which in turn ligates to SCS2 and phosphatidic acid present in the donor membrane, forming a zone of apposition that facilitates PtdSer transfer (PubMed:24366873)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DM26", "ec_number_list": "", "go_molecular_function": "GO:0043495 protein-membrane adaptor activity;GO:0035091 phosphatidylinositol binding;GO:0033149 FFAT motif binding", "go_cellular_component": "GO:0071561 nucleus-vacuole junction;GO:0005635 nuclear envelope;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0031965 nuclear membrane", "go_biological_process": "GO:0061163 endoplasmic reticulum polarization;GO:0031509 subtelomeric heterochromatin formation;GO:0090158 endoplasmic reticulum membrane organization;GO:0060304 regulation of phosphatidylinositol dephosphorylation;GO:0042308 negative regulation of protein import into nucleus", "synthesized_glycan_count": 0, "hit_score": 2.8, "record_id": "P40075-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40078-1", "uniprot_id": "NSA2_YEAST", "mass": 29723.0, "length": 261, "protein_name": "Ribosome biogenesis protein NSA2", "gene_name": "NSA2", "organism": "Yeast", "refseq_name": "rRNA-processing protein NSA2", "refseq_ac": "NP_011052", "gene_names_uniprotkb": "NSA2; SYGP-ORF47", "gene_names_refseq": "NSA2", "protein_names_uniprotkb": "Ribosome biogenesis protein NSA2; NOP7-associated protein 2", "protein_names_refseq": "rRNA-processing protein NSA2", "tax_id": 559292, "disease": "", "pathway": " (sce:YER126C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "11583614;14562106;15100437;16544271;16861225;17322287;17443350;22814378;24374639;25404745;27251291;33491328;9169868", "class_list": "", "function": "Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles. Under normal, rapid growth conditions, high levels of NSA2 would allow the progression of pre-60S particles through the ITS2 processing., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DM32", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0030687 preribosome, large subunit precursor", "go_biological_process": "GO:0042273 ribosomal large subunit biogenesis;GO:0000460 maturation of 5.8S rRNA;GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000470 maturation of LSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P40078-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40164-1", "uniprot_id": "PP4R3_YEAST", "mass": 98053.0, "length": 858, "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 3", "gene_name": "PSY2", "organism": "Yeast", "refseq_name": "Psy2p", "refseq_ac": "NP_014198", "gene_names_uniprotkb": "PSY2; N1366", "gene_names_refseq": "PSY2", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase 4 regulatory subunit 3; PP4R3", "protein_names_refseq": "Psy2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL201C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562095;14562106;16085932;16299494;23749301;24374639;33491328;7725799;9169873", "class_list": "", "function": "Core regulatory subunit of the histone H2A phosphatase complex, which dephosphorylates H2AS128ph (gamma-H2A) that has been displaced from sites of DNA lesions in the double-stranded DNA break repair process. Dephosphorylation is necessary for efficient recovery from the DNA damage checkpoint., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W0Y7", "ec_number_list": "", "go_molecular_function": "GO:0019888 protein phosphatase regulator activity;GO:0072542 protein phosphatase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0030289 protein phosphatase 4 complex", "go_biological_process": "GO:0051598 meiotic recombination checkpoint signaling;GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining;GO:0006974 DNA damage response;GO:2000002 negative regulation of DNA damage checkpoint;GO:2000779 regulation of double-strand break repair", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P40164-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40186-1", "uniprot_id": "PCL7_YEAST", "mass": 32037.0, "length": 285, "protein_name": "PHO85 cyclin-7", "gene_name": "PCL7", "organism": "Yeast", "refseq_name": "Pcl7p", "refseq_ac": "NP_012214", "gene_names_uniprotkb": "PCL7; PAP1", "gene_names_refseq": "PCL7", "protein_names_uniprotkb": "PHO85 cyclin-7; PHO85-associated protein 1", "protein_names_refseq": "Pcl7p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL050W)", "pathway_count": 1, "publication_count": 24, "publication_id_list": "11069666;11602261;12006994;12098764;12174291;12407105;14562095;14562106;15721288;18407956;19779198;19795423;19823750;20489023;20702584;21126336;21177495;24374639;32597660;33481703;33491328;34965436;9032248;9169870", "class_list": "", "function": "Cyclin partner of the cyclin-dependent kinase (CDK) PHO85. Together with cyclin PCL6, controls glycogen phosphorylase and glycogen synthase activities in response to nutrient availablility. The PCL7-PHO85 cyclin-CDK holoenzyme has GLC8 kinase activity and phosphorylates and inactivates the phosphatase PP1-2 inhibitor GLC8, causing activation of PP1-2, which then dephosphorylates and activates glycogen phosphorylase. PCL7-PHO85 also phosphorylates MMR1 and YJL084C., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 16, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVN1", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding;GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000307 cyclin-dependent protein kinase holoenzyme complex", "go_biological_process": "GO:0005981 regulation of glycogen catabolic process;GO:0051301 cell division;GO:0005977 glycogen metabolic process;GO:0031647 regulation of protein stability;GO:0005979 regulation of glycogen biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "P40186-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40303-1", "uniprot_id": "PSA4_YEAST", "mass": 28439.0, "length": 254, "protein_name": "Proteasome subunit alpha type-4", "gene_name": "PRE6", "organism": "Yeast", "refseq_name": "proteasome core particle subunit alpha 4", "refseq_ac": "NP_014604", "gene_names_uniprotkb": "PRE6", "gene_names_refseq": "PRE6", "protein_names_uniprotkb": "Proteasome subunit alpha type-4; Macropain subunit PRE6; Multicatalytic endopeptidase complex subunit PRE6; Proteasome component PRE6; Proteinase YSCE subunit PRE6", "protein_names_refseq": "proteasome core particle subunit alpha 4", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL038W); (R-SCE-1236974); (R-SCE-1236978); (R-SCE-5668541); (R-SCE-5689880); (R-SCE-9907900); (R-SCE-9912633)", "pathway_count": 7, "publication_count": 22, "publication_id_list": "11062564;11081519;11493007;11500370;14562095;14562106;16531229;16608349;16793518;17287358;18407956;20227375;20486117;22927375;23749301;24374639;32597660;33481703;33491328;7918444;9087403;9169874", "class_list": "", "function": "The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W229", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding", "go_cellular_component": "GO:0034515 proteasome storage granule;GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0019773 proteasome core complex, alpha-subunit complex;GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0010499 proteasomal ubiquitin-independent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "P40303-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40343-1", "uniprot_id": "VPS27_YEAST", "mass": 70974.0, "length": 622, "protein_name": "Vacuolar protein sorting-associated protein 27", "gene_name": "VPS27", "organism": "Yeast", "refseq_name": "ESCRT-0 subunit protein VPS27", "refseq_ac": "NP_014403", "gene_names_uniprotkb": "VPS27; DID7; GRD11; N2038; SSV17; VPL23; VPT27", "gene_names_refseq": "DID7; GRD11; SSV17; VPL23; VPS27; VPT27", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 27; Golgi retention defective protein 11", "protein_names_refseq": "ESCRT-0 subunit protein VPS27", "tax_id": 559292, "disease": "Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (sce:YNR006W)", "pathway_count": 1, "publication_count": 50, "publication_id_list": "10367894;11208109;11416128;11872141;11988742;12006563;12055639;12706728;12750381;12900393;12970172;14562095;14562106;14581452;1493335;15086794;15107463;15166140;15169871;15665377;17101773;17101785;17135292;17330950;17563356;18407956;18508771;19779198;19795423;19823750;20702584;21126336;21177495;22106047;22218487;22918958;23749301;24374639;30527664;3062374;32597660;33481703;33491328;7593183;7900425;8649377;9015300;9169873;9265642;9702203", "class_list": "", "function": "Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane (PubMed:11416128, PubMed:11872141, PubMed:12055639, PubMed:12900393, PubMed:14581452, PubMed:1493335, PubMed:15086794, PubMed:15107463, PubMed:15166140, PubMed:17135292, PubMed:18508771, PubMed:3062374, PubMed:9265642). Controls exit from the prevacuolar compartment (PVC) in both the forward direction to the vacuole and the return to the Golgi (PubMed:11208109, PubMed:8649377, PubMed:9015300). Allows VPS10 to return to the (trans-Golgi network) TGN from the PVC (PubMed:8649377). Might also function as an alternate adapter in the COPIb clathrin-like coat (PubMed:17101773)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 21, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1I1", "ec_number_list": "", "go_molecular_function": "GO:0036435 K48-linked polyubiquitin modification-dependent protein binding;GO:0008270 zinc ion binding;GO:0019904 protein domain specific binding;GO:0046982 protein heterodimerization activity;GO:0032266 phosphatidylinositol-3-phosphate binding", "go_cellular_component": "GO:0033565 ESCRT-0 complex;GO:0005768 endosome;GO:0010008 endosome membrane;GO:0005774 vacuolar membrane;GO:0032991 protein-containing complex", "go_biological_process": "GO:0071985 multivesicular body sorting pathway;GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0045053 protein retention in Golgi apparatus;GO:0009306 protein secretion;GO:0006995 cellular response to nitrogen starvation", "synthesized_glycan_count": 0, "hit_score": 5.1, "record_id": "P40343-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40356-1", "uniprot_id": "MED3_YEAST", "mass": 43079.0, "length": 397, "protein_name": "Mediator of RNA polymerase II transcription subunit 3", "gene_name": "PGD1", "organism": "Yeast", "refseq_name": "Pgd1p", "refseq_ac": "NP_011490", "gene_names_uniprotkb": "PGD1; HRS1; MED3", "gene_names_refseq": "HRS1; MED3; PGD1", "protein_names_uniprotkb": "Mediator of RNA polymerase II transcription subunit 3; Hyper-recombination suppressor protein 1; Mediator complex subunit 3; Poly-glutamine domain protein 1", "protein_names_refseq": "Pgd1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL025C)", "pathway_count": 1, "publication_count": 25, "publication_id_list": "10722672;12191485;12748633;14562095;14562106;15175151;15477388;16002404;16076843;16109375;16263706;16630888;17192271;17322287;19779198;22814378;23749301;24374639;33229814;33481703;33491328;7975891;8849881;9169869;9420330", "class_list": "", "function": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. The Mediator complex unfolds to an extended conformation and partially surrounds RNA polymerase II, specifically interacting with the unphosphorylated form of the C-terminal domain (CTD) of RNA polymerase II. The Mediator complex dissociates from the RNA polymerase II holoenzyme and stays at the promoter when transcriptional elongation begins. PGD1/MED3 is also involved in direct repeat recombination., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 5, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 5, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 5, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "D6VUB3;Q6B1W3", "ec_number_list": "", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016592 mediator complex;GO:0070847 core mediator complex", "go_biological_process": "GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0034605 cellular response to heat;GO:0032968 positive regulation of transcription elongation by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 3.2, "record_id": "P40356-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40362-1", "uniprot_id": "UTP18_YEAST", "mass": 66424.0, "length": 594, "protein_name": "U3 small nucleolar RNA-associated protein 18", "gene_name": "UTP18", "organism": "Yeast", "refseq_name": "Utp18p", "refseq_ac": "NP_012466", "gene_names_uniprotkb": "UTP18; HRE594; J1098", "gene_names_refseq": "UTP18", "protein_names_uniprotkb": "U3 small nucleolar RNA-associated protein 18; U three protein 18; U3 snoRNA-associated protein 18", "protein_names_refseq": "Utp18p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL069C); (R-SCE-6791226)", "pathway_count": 2, "publication_count": 14, "publication_id_list": "14562095;14562106;15590835;17322287;18407956;19779198;20884785;23749301;24374639;24466140;33481703;33491328;7762302;8641269", "class_list": "", "function": "Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWB4", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0034388 Pwp2p-containing subcomplex of 90S preribosome;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0030686 90S preribosome;GO:0032040 small-subunit processome", "go_biological_process": "GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0030490 maturation of SSU-rRNA;GO:0000292 RNA fragment catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P40362-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40368-1", "uniprot_id": "NUP82_YEAST", "mass": 82085.0, "length": 713, "protein_name": "Nucleoporin NUP82", "gene_name": "NUP82", "organism": "Yeast", "refseq_name": "linker nucleoporin NUP82", "refseq_ac": "NP_012474", "gene_names_uniprotkb": "NUP82; HRB187; J1135", "gene_names_refseq": "HRB187; NUP82", "protein_names_uniprotkb": "Nucleoporin NUP82; Nuclear pore protein NUP82", "protein_names_refseq": "linker nucleoporin NUP82", "tax_id": 559292, "disease": "fetal akinesia deformation sequence syndrome 4 (Disease Ontology:DOID:0111379)", "pathway": " (sce:YJL061W)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "10684247;10801828;10891509;11689687;11739405;12791264;14562106;17546040;18407956;21930948;22480613;23749301;24374639;25646085;32597660;33481703;33491328;7559750;7559751;7762302;8641269;9843582", "class_list": "", "function": "Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. It is specifically involved as part of the NUP82-NUP159-NSP1 subcomplex in nuclear mRNA and pre-ribosome export by acting as a linker tethering nucleoporins that are directly involved in nuclear transport to the NPC via its coiled-coil domain., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWC1", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0017056 structural constituent of nuclear pore", "go_cellular_component": "GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005643 nuclear pore;GO:0005829 cytosol;GO:0031965 nuclear membrane", "go_biological_process": "GO:0000055 ribosomal large subunit export from nucleus;GO:0006406 mRNA export from nucleus;GO:0006913 nucleocytoplasmic transport;GO:0006611 protein export from nucleus;GO:0006606 protein import into nucleus", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "P40368-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40454-1", "uniprot_id": "PTPA1_YEAST", "mass": 45082.0, "length": 393, "protein_name": "Serine/threonine-protein phosphatase 2A activator 1", "gene_name": "RRD1", "organism": "Yeast", "refseq_name": "peptidylprolyl isomerase RRD1", "refseq_ac": "NP_012113", "gene_names_uniprotkb": "RRD1; NCS1; YPA1", "gene_names_refseq": "RRD1; YPA1", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase 2A activator 1; 5.2.1.8; PPIase PTPA-1; Peptidyl-prolyl cis-trans isomerase PTPA-1; Phosphotyrosyl phosphatase activator 1; Rotamase PTPA-1", "protein_names_refseq": "peptidylprolyl isomerase RRD1", "tax_id": 559292, "disease": "Parkinson's disease 25 (Disease Ontology:DOID:0070486)", "pathway": " (sce:YIL153W)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "11134337;11262194;12952889;14562095;14562106;15150670;15447631;15689491;16380387;16885030;18407956;19779198;22218487;23749301;24374639;32801125;33481703;33491328;9169870", "class_list": "", "function": "PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for TAP42-associated PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex. Involved in the regulation of cell cycle progression, mitotic spindle formation, bud morphogenesis and DNA repair., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVD4", "ec_number_list": "5.2.1.8", "go_molecular_function": "GO:0019888 protein phosphatase regulator activity;GO:0008160 protein tyrosine phosphatase activator activity;GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000159 protein phosphatase type 2A complex;GO:0000785 chromatin", "go_biological_process": "GO:0006281 DNA repair;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006914 autophagy;GO:0000082 G1/S transition of mitotic cell cycle;GO:0031929 TOR signaling", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P40454-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40458-1", "uniprot_id": "ATG32_YEAST", "mass": 58969.0, "length": 529, "protein_name": "Autophagy-related protein 32", "gene_name": "ATG32", "organism": "Yeast", "refseq_name": "mitophagy protein ATG32", "refseq_ac": "NP_012120", "gene_names_uniprotkb": "ATG32; ECM17", "gene_names_refseq": "ATG32; ECM37", "protein_names_uniprotkb": "Autophagy-related protein 32; Extracellular mutant protein 37", "protein_names_refseq": "mitophagy protein ATG32", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL146C)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "17322287;19619494;19619495;19770589;19793921;21576396;21757540;22157017;22308029;22643220;22914317;23749301;23897086;24374639;33481703;33491328;38964378;9169870;9335584", "class_list": "", "function": "Mitophagy-specific receptor that recruits the autophagic machinery to mitochondria and regulates selective degradation of mitochondria. Mitophagy contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Recruits ATG11 to the surface of mitochondria. Also promotes autophagy-dependent peroxisome degradation., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVE1", "ec_number_list": "", "go_molecular_function": "GO:0140580 mitochondrion autophagosome adaptor activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0005774 vacuolar membrane;GO:0034045 phagophore assembly site membrane", "go_biological_process": "GO:0000422 autophagy of mitochondrion;GO:0031930 mitochondria-nucleus signaling pathway", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P40458-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40482-1", "uniprot_id": "SEC24_YEAST", "mass": 103636.0, "length": 926, "protein_name": "Protein transport protein SEC24", "gene_name": "SEC24", "organism": "Yeast", "refseq_name": "COPII subunit SEC24", "refseq_ac": "NP_012157", "gene_names_uniprotkb": "SEC24; ANU1", "gene_names_refseq": "ANU1; SEC24", "protein_names_uniprotkb": "Protein transport protein SEC24; Abnormal nuclear morphology 1", "protein_names_refseq": "COPII subunit SEC24", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL109C); (R-SCE-204005); (R-SCE-5694530); (R-SCE-983170)", "pathway_count": 4, "publication_count": 43, "publication_id_list": "10097109;10198022;10564255;10712514;10720463;10749860;10753972;11086000;11389436;11535824;11560939;11717432;11726510;12235121;12239560;12655150;12671686;12778054;12941276;12941277;14562095;14627716;16269340;17261844;17322287;17330950;18407956;19684113;21126336;23749301;24374639;27855785;32597660;33481703;33491328;8548805;8930902;9023343;9169870;9325247;9428766;9568718;9685263", "class_list": "", "function": "Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. SEC24 specifically recruits cargo proteins like BET1 or SYS1 to the COPII vesicles. The SEC23/24 complex is also involved in internalization of plasma membrane proteins like the maltose transporter., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVH8", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0005048 signal sequence binding;GO:0000149 SNARE binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0070971 endoplasmic reticulum exit site;GO:0030127 COPII vesicle coat", "go_biological_process": "GO:0090110 COPII-coated vesicle cargo loading;GO:0006886 intracellular protein transport;GO:0016236 macroautophagy;GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport;GO:0070863 positive regulation of protein exit from endoplasmic reticulum", "synthesized_glycan_count": 0, "hit_score": 4.4, "record_id": "P40482-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40484-1", "uniprot_id": "MOB1_YEAST", "mass": 35882.0, "length": 314, "protein_name": "DBF2 kinase activator protein MOB1", "gene_name": "MOB1", "organism": "Yeast", "refseq_name": "Mob1p", "refseq_ac": "NP_012160", "gene_names_uniprotkb": "MOB1", "gene_names_refseq": "MOB1", "protein_names_uniprotkb": "DBF2 kinase activator protein MOB1; MPS1 binder 1; Maintenance of ploidy protein MOB1", "protein_names_refseq": "Mob1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL106W)", "pathway_count": 1, "publication_count": 30, "publication_id_list": "11404483;11434459;11564880;11875433;14562095;14562106;15665377;16176976;16934835;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20489023;20702584;21126336;21177495;22218487;23749301;24374639;30516470;32597660;33481703;33491328;9169870;9436989;9528782", "class_list": "", "function": "Functions as an activator subunit for the DBF2 protein kinase. Binds to DBF2, which is required for the phosphorylation and activation of DBF2 by the upstream kinase CDC15 in late anaphase. DBF2-MOB1 is part of the mitotic exit network (MEN) signaling cascade, which regulates release from the nucleus and activity of phosphatase CDC14. Required for inactivation of mitotic cyclin-dependent kinase for exit from mitosis, cytokinesis and G1 gene transcription., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 18, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVI1", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0030295 protein kinase activator activity;GO:0019207 kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000775 chromosome, centromeric region;GO:0034399 nuclear periphery;GO:0005816 spindle pole body", "go_biological_process": "GO:0007165 signal transduction;GO:0051301 cell division;GO:0010458 exit from mitosis;GO:0000281 mitotic cytokinesis;GO:0007096 regulation of exit from mitosis", "synthesized_glycan_count": 0, "hit_score": 3.1, "record_id": "P40484-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40494-1", "uniprot_id": "PRK1_YEAST", "mass": 91032.0, "length": 810, "protein_name": "Actin-regulating kinase PRK1", "gene_name": "PRK1", "organism": "Yeast", "refseq_name": "serine/threonine protein kinase PRK1", "refseq_ac": "NP_012171", "gene_names_uniprotkb": "PRK1; PAK1", "gene_names_refseq": "PAK1; PRK1", "protein_names_uniprotkb": "Actin-regulating kinase PRK1; 2.7.11.1; p53-regulating kinase 1", "protein_names_refseq": "serine/threonine protein kinase PRK1", "tax_id": 559292, "disease": "Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (sce:YIL095W)", "pathway_count": 1, "publication_count": 30, "publication_id_list": "10087264;11668184;11694597;11739778;12956961;13679512;14562095;14562106;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20489023;20702584;21126336;21177495;23749301;24374639;30516470;32597660;33229814;33481703;33491328;7597081;9169870;9885245", "class_list": "", "function": "Protein kinase involved in the regulation of actin cytoskeleton organization and endocytosis (PubMed:10087264, PubMed:11694597, PubMed:11739778, PubMed:9885245). Phosphorylates PAN1 which disrupts the interaction between PAN1 and END3, and between PAN1 and SLA1 (PubMed:11739778, PubMed:13679512, PubMed:9885245). Phosphorylates SCD5 (PubMed:12956961, PubMed:13679512). Preferentially, phosphorylates substrates on threonine residues in a [L/I/V/M]-x-x-[Q/N/T/S]-x-T-G motif (PubMed:11739778, PubMed:12956961, PubMed:13679512, PubMed:9885245)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 10, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 10, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 10, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 37, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "D6VVJ2;Q02553", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0030479 actin cortical patch;GO:0043332 mating projection tip", "go_biological_process": "GO:0007015 actin filament organization;GO:0031333 negative regulation of protein-containing complex assembly;GO:0000147 actin cortical patch assembly;GO:1900186 negative regulation of clathrin-dependent endocytosis;GO:0120133 negative regulation of actin cortical patch assembly", "synthesized_glycan_count": 0, "hit_score": 4.2, "record_id": "P40494-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40563-1", "uniprot_id": "AIM21_YEAST", "mass": 74763.0, "length": 679, "protein_name": "Altered inheritance of mitochondria protein 21", "gene_name": "AIM21", "organism": "Yeast", "refseq_name": "Aim21p", "refseq_ac": "NP_012268", "gene_names_uniprotkb": "AIM21; YIB3W", "gene_names_refseq": "AIM21", "protein_names_uniprotkb": "Altered inheritance of mitochondria protein 21", "protein_names_refseq": "Aim21p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIR003W)", "pathway_count": 1, "publication_count": 32, "publication_id_list": "11668184;14562095;14562106;14737190;15665377;16702403;17164236;17287358;17330950;17563356;18407956;19053807;19300474;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22218487;23749301;24374639;24909858;28270554;30516470;31208443;32597660;33481703;33491328;7762303;9169870", "class_list": "", "function": "Involved in mitochondrial migration along actin filaments., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 64, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VVT3", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0015629 actin cytoskeleton;GO:0030479 actin cortical patch;GO:0110131 Aim21-Tda2 complex;GO:0043332 mating projection tip", "go_biological_process": "GO:0034642 mitochondrion migration along actin filament;GO:0030837 negative regulation of actin filament polymerization;GO:2000813 negative regulation of barbed-end actin filament capping", "synthesized_glycan_count": 0, "hit_score": 3.3, "record_id": "P40563-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40568-1", "uniprot_id": "DSN1_YEAST", "mass": 65692.0, "length": 576, "protein_name": "Kinetochore-associated protein DSN1", "gene_name": "DSN1", "organism": "Yeast", "refseq_name": "MIND complex subunit DSN1", "refseq_ac": "NP_012275", "gene_names_uniprotkb": "DSN1; YIB10W", "gene_names_refseq": "DSN1", "protein_names_uniprotkb": "Kinetochore-associated protein DSN1", "protein_names_refseq": "MIND complex subunit DSN1", "tax_id": 559292, "disease": "", "pathway": " (sce:YIR010W); (R-SCE-6798695)", "pathway_count": 2, "publication_count": 25, "publication_id_list": "12455957;14562106;14581449;14602074;14633972;14657030;14690591;15665377;18407956;19779198;19795423;19823750;20489023;20819936;20923974;22218487;23749301;24374639;30516470;31037469;32597660;33481703;33491328;7762303;9169870", "class_list": "", "function": "Acts as an essential component of the kinetochore MIND complex, which is required for the spindle checkpoint and kinetochore integrity. MIND plays a role in establishing a bipolar spindle-kinetochore interaction by joining kinetochore subunits contacting DNA to those contacting microtubules., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVU0", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000922 spindle pole;GO:0005634 nucleus;GO:0000776 kinetochore;GO:0000940 outer kinetochore;GO:0000444 MIS12/MIND type complex", "go_biological_process": "GO:0051455 spindle attachment to meiosis I kinetochore;GO:0007059 chromosome segregation;GO:0008608 attachment of spindle microtubules to kinetochore;GO:0051301 cell division;GO:0051754 meiotic sister chromatid cohesion, centromeric", "synthesized_glycan_count": 0, "hit_score": 2.6, "record_id": "P40568-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40577-1", "uniprot_id": "MND2_YEAST", "mass": 42826.0, "length": 368, "protein_name": "Anaphase-promoting complex subunit MND2", "gene_name": "MND2", "organism": "Yeast", "refseq_name": "Mnd2p", "refseq_ac": "NP_012291", "gene_names_uniprotkb": "MND2", "gene_names_refseq": "MND2", "protein_names_uniprotkb": "Anaphase-promoting complex subunit MND2; Meiotic nuclear division protein 2", "protein_names_refseq": "Mnd2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YIR025W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "12477395;12609981;19779198;23749301;24374639;32597660;33481703;33491328;9169870", "class_list": "", "function": "Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome. In early mitosis, the APC/C is activated by CDC20 and targets securin PDS1, the B-type cyclin CLB5, and other anaphase inhibitory proteins for proteolysis, thereby triggering the separation of sister chromatids at the metaphase-to-anaphase transition. In late mitosis and in G1, degradation of CLB5 allows activation of the APC/C by CDH1, which is needed to destroy CDC20 and the B-type cyclin CLB2 to allow exit from mitosis and creating the low CDK state necessary for cytokinesis and for reforming prereplicative complexes in G1 prior to another round of replication., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVV6", "ec_number_list": "", "go_molecular_function": "GO:1990948 ubiquitin ligase inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005680 anaphase-promoting complex", "go_biological_process": "GO:1902426 deactivation of mitotic spindle assembly checkpoint;GO:0051301 cell division;GO:0007346 regulation of mitotic cell cycle;GO:0016567 protein ubiquitination;GO:0031145 anaphase-promoting complex-dependent catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P40577-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40856-1", "uniprot_id": "SA185_YEAST", "mass": 121403.0, "length": 1058, "protein_name": "SIT4-associating protein SAP185", "gene_name": "SAP185", "organism": "Yeast", "refseq_name": "Sap185p", "refseq_ac": "NP_012437", "gene_names_uniprotkb": "SAP185; J0840", "gene_names_refseq": "SAP185", "protein_names_uniprotkb": "SIT4-associating protein SAP185", "protein_names_refseq": "Sap185p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL098W); (R-SCE-204005)", "pathway_count": 2, "publication_count": 16, "publication_id_list": "14562106;15665377;18407956;19779198;20190278;20489023;22106047;23749301;24374639;32597660;33481703;33491328;7483851;7871887;8641269;8649382", "class_list": "", "function": "Associates with the SIT4 phosphatase in a cell cycle dependent manner. May be directly or indirectly involved in SIT4-dependent functions in budding and in normal G1 cyclin expression., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 27, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VW86", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0019888 protein phosphatase regulator activity;GO:0019903 protein phosphatase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0000082 G1/S transition of mitotic cell cycle;GO:0009966 regulation of signal transduction;GO:1903766 positive regulation of potassium ion export across plasma membrane;GO:0002098 tRNA wobble uridine modification", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P40856-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40957-1", "uniprot_id": "MAD1_YEAST", "mass": 87651.0, "length": 749, "protein_name": "Spindle assembly checkpoint component MAD1", "gene_name": "MAD1", "organism": "Yeast", "refseq_name": "coiled-coil domain-containing protein MAD1", "refseq_ac": "NP_011429", "gene_names_uniprotkb": "MAD1", "gene_names_refseq": "MAD1", "protein_names_uniprotkb": "Spindle assembly checkpoint component MAD1; Mitotic arrest deficient protein 1", "protein_names_refseq": "coiled-coil domain-containing protein MAD1", "tax_id": 559292, "disease": "lymphoma (Disease Ontology:DOID:0060058); mosaic variegated aneuploidy syndrome 7 with inflammation and tumor predisposition (Disease Ontology:DOID:0060982); prostate cancer (Disease Ontology:DOID:10283); microcephaly (Disease Ontology:DOID:10907)", "pathway": " (sce:YGL086W)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "10436016;10837255;11726501;14562106;18407956;19779198;19795423;19823750;23749301;24374639;30516470;33481703;33491328;7593191;8688079;9169869;9290212", "class_list": "", "function": "Central component of the spindle assembly checkpoint. Thought to recruit MAD2 to unattached kinetochores. During checkpoint activity, MAD2 is relayed from the MAD1-MAD2 complex to the mitotic checkpoint complex (MCC). The formation of a MAD1-BUB1-BUB3 complex seems to be required for the spindle checkpoint mechanism., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VU58", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0000776 kinetochore;GO:0072686 mitotic spindle", "go_biological_process": "GO:0051315 attachment of mitotic spindle microtubules to kinetochore;GO:0044774 mitotic DNA integrity checkpoint signaling;GO:0006913 nucleocytoplasmic transport;GO:0051301 cell division;GO:0007094 mitotic spindle assembly checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P40957-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40958-1", "uniprot_id": "MAD2_YEAST", "mass": 22284.0, "length": 196, "protein_name": "Mitotic spindle checkpoint component MAD2", "gene_name": "MAD2", "organism": "Yeast", "refseq_name": "spindle checkpoint protein MAD2", "refseq_ac": "NP_012504", "gene_names_uniprotkb": "MAD2; J1256", "gene_names_refseq": "MAD2", "protein_names_uniprotkb": "Mitotic spindle checkpoint component MAD2; Mitotic MAD2 protein", "protein_names_refseq": "spindle checkpoint protein MAD2", "tax_id": 559292, "disease": "microcephaly (Disease Ontology:DOID:10907); cancer (Disease Ontology:DOID:162)", "pathway": " (sce:YJL030W); (R-SCE-141405); (R-SCE-141430)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10436016;11726501;14562106;15879521;1651172;17322287;24374639;33491328;8232541;8641269;9461437", "class_list": "", "function": "Central component of the spindle assembly checkpoint which is a feedback control that prevents cells with incompletely assembled spindles from leaving mitosis. Thought to be recruited to unattached kinetochores by MAD1. During checkpoint activity, MAD2 is relayed from the MAD1-MAD2 complex to the mitotic checkpoint complex (MCC). MCC and presumably the MAD2-CDC20 subcomplex inhibit the ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) by preventing its activation by CDC20., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWF2", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000776 kinetochore;GO:0033597 mitotic checkpoint complex", "go_biological_process": "GO:0044774 mitotic DNA integrity checkpoint signaling;GO:0051301 cell division;GO:0007094 mitotic spindle assembly checkpoint signaling;GO:1902499 positive regulation of protein autoubiquitination", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P40958-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40969-1", "uniprot_id": "CBF3B_YEAST", "mass": 71358.0, "length": 608, "protein_name": "Centromere DNA-binding protein complex CBF3 subunit B", "gene_name": "CEP3", "organism": "Yeast", "refseq_name": "Cep3p", "refseq_ac": "NP_013891", "gene_names_uniprotkb": "CEP3; CBF3B; CBF3; CSL1; YM8520.17C", "gene_names_refseq": "CBF3; CEP3; CSL1", "protein_names_uniprotkb": "Centromere DNA-binding protein complex CBF3 subunit B; Centromere protein 3", "protein_names_refseq": "Cep3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR168C)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "14562106;14581449;15090617;17563356;18407956;20190278;23749301;24374639;24440502;26829389;33491328;7876302;7957085;9169872", "class_list": "", "function": "Acts as a component of the centromere DNA-binding protein complex CBF3, which is essential for chromosome segregation and movement of centromeres along microtubules. CBF3 is required for the recruitment of other kinetochore complexes to CEN DNA. It plays a role in the attachment of chromosomes to the spindle and binds selectively to a highly conserved DNA sequence called CDEIII, found in centromers and in several promoters., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZZ0", "ec_number_list": "", "go_molecular_function": "GO:0008301 DNA binding, bending;GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0019237 centromeric DNA binding", "go_cellular_component": "GO:0000776 kinetochore;GO:0031518 CBF3 complex", "go_biological_process": "GO:0051382 kinetochore assembly;GO:0007094 mitotic spindle assembly checkpoint signaling;GO:0000921 septin ring assembly", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P40969-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40970-1", "uniprot_id": "LCB2_YEAST", "mass": 63111.0, "length": 561, "protein_name": "Serine palmitoyltransferase 2", "gene_name": "LCB2", "organism": "Yeast", "refseq_name": "serine C-palmitoyltransferase LCB2", "refseq_ac": "NP_010347", "gene_names_uniprotkb": "LCB2; D4246; SCS1; TSC1; YD9609.16", "gene_names_refseq": "LCB2; SCS1; TSC1", "protein_names_uniprotkb": "Serine palmitoyltransferase 2; 2.3.1.50; Long chain base biosynthesis protein 2; SPT 2", "protein_names_refseq": "serine C-palmitoyltransferase LCB2", "tax_id": 559292, "disease": "hereditary sensory and autonomic neuropathy type 1C (Disease Ontology:DOID:0070157); hereditary sensory and autonomic neuropathy type 1 (Disease Ontology:DOID:0070162); psoriasis (Disease Ontology:DOID:8893)", "pathway": " (sce:YDR062W)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10713067;11781309;14562095;14562106;15485854;17322287;20182505;24374639;33481703;33491328;8058731;8063782;8789263;9169867", "class_list": "", "function": "Catalytic subunit of serine palmitoyltransferase (SPT), which catalyzes the committed step in the synthesis of sphingolipids, the condensation of serine with palmitoyl CoA to form the long chain base 3-ketosphinganine., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS48;Q66RG8", "ec_number_list": "2.3.1.50", "go_molecular_function": "GO:0004758 serine C-palmitoyltransferase activity;GO:0030170 pyridoxal phosphate binding", "go_cellular_component": "GO:0017059 serine palmitoyltransferase complex;GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0046513 ceramide biosynthetic process;GO:0030148 sphingolipid biosynthetic process;GO:0046512 sphingosine biosynthetic process;GO:0090156 intracellular sphingolipid homeostasis", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P40970-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40994-1", "uniprot_id": "ARF3_YEAST", "mass": 20696.0, "length": 183, "protein_name": "ADP-ribosylation factor 3", "gene_name": "ARF3", "organism": "Yeast", "refseq_name": "Arf family GTPase ARF3", "refseq_ac": "NP_014737", "gene_names_uniprotkb": "ARF3; YOR3172W", "gene_names_refseq": "ARF3; ARL2", "protein_names_uniprotkb": "ADP-ribosylation factor 3", "protein_names_refseq": "Arf family GTPase ARF3", "tax_id": 559292, "disease": "candidiasis (Disease Ontology:DOID:1508); alcohol use disorder (Disease Ontology:DOID:1574)", "pathway": " (sce:YOR094W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562106;15504911;17322287;24374639;33481703;33491328;8063710;9169874;9200815", "class_list": "", "function": "GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2F5", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0008047 enzyme activator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005934 cellular bud tip", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006897 endocytosis;GO:0051017 actin filament bundle assembly;GO:0010513 positive regulation of phosphatidylinositol biosynthetic process;GO:0016192 vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P40994-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P41695-1", "uniprot_id": "BUB1_YEAST", "mass": 117868.0, "length": 1021, "protein_name": "Spindle assembly checkpoint serine/threonine-protein kinase BUB1", "gene_name": "BUB1", "organism": "Yeast", "refseq_name": "protein kinase BUB1", "refseq_ac": "NP_011704", "gene_names_uniprotkb": "BUB1; G7542", "gene_names_refseq": "BUB1", "protein_names_uniprotkb": "Spindle assembly checkpoint serine/threonine-protein kinase BUB1; 2.7.11.1; Checkpoint serine/threonine-protein kinase BUB1", "protein_names_refseq": "protein kinase BUB1", "tax_id": 559292, "disease": "primary autosomal recessive microcephaly 30 (Disease Ontology:DOID:0051041); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (sce:YGR188C); (R-SCE-141430)", "pathway_count": 2, "publication_count": 19, "publication_id_list": "10837255;12769845;14562106;17227844;19779198;20489023;21298086;22031224;22521787;23749301;24066227;24374639;32597660;33481703;33491328;34861183;7969164;9133739;9169869", "class_list": "", "function": "Involved in mitotic spindle assembly checkpoint signaling, a process that delays anaphase until chromosomes are bioriented on the spindle, and in the repair of incorrect mitotic kinetochore-spindle microtubule attachments (PubMed:12769845, PubMed:24066227, PubMed:7969164). The formation of a MAD1-BUB1-BUB3 complex seems to be required for the spindle checkpoint mechanism (PubMed:7969164). Phosphorylates BUB3 (PubMed:7969164). Also autophosphorylates (PubMed:7969164). Associates with centromere (CEN) DNA via interaction with SKP1 (PubMed:12769845). The association with SKP1 is required for the mitotic delay induced by kinetochore tension defects, but not for the arrest induced by spindle depolymerization or kinetochore assembly defects (PubMed:12769845)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 19, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUX1", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000776 kinetochore;GO:1990298 bub1-bub3 complex;GO:0000779 condensed chromosome, centromeric region;GO:0000940 outer kinetochore", "go_biological_process": "GO:0016236 macroautophagy;GO:0051754 meiotic sister chromatid cohesion, centromeric;GO:0007094 mitotic spindle assembly checkpoint signaling;GO:0034501 protein localization to kinetochore;GO:0031134 sister chromatid biorientation", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P41695-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P41834-1", "uniprot_id": "UFE1_YEAST", "mass": 40539.0, "length": 346, "protein_name": "Syntaxin UFE1", "gene_name": "UFE1", "organism": "Yeast", "refseq_name": "Ufe1p", "refseq_ac": "NP_014718", "gene_names_uniprotkb": "UFE1; YOR29-26", "gene_names_refseq": "UFE1", "protein_names_uniprotkb": "Syntaxin UFE1", "protein_names_refseq": "Ufe1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR075W); (R-SCE-6811434)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "24374639;33491328;8929391;9133743;9169874;9214619", "class_list": "", "function": "Syntaxin required for targeting and fusion of Golgi-derived retrograde transport vesicles with the ER., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2D8", "ec_number_list": "", "go_molecular_function": "GO:0005484 SNAP receptor activity", "go_cellular_component": "GO:0098554 cytoplasmic side of endoplasmic reticulum membrane;GO:0005783 endoplasmic reticulum;GO:0031201 SNARE complex;GO:0012508 Golgi to ER transport vesicle membrane", "go_biological_process": "GO:0015031 protein transport;GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0016320 endoplasmic reticulum membrane fusion;GO:0048279 vesicle fusion with endoplasmic reticulum", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P41834-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P42846-1", "uniprot_id": "KRI1_YEAST", "mass": 68654.0, "length": 591, "protein_name": "Protein KRI1", "gene_name": "KRI1", "organism": "Yeast", "refseq_name": "Kri1p", "refseq_ac": "NP_014091", "gene_names_uniprotkb": "KRI1; N0388", "gene_names_refseq": "KRI1", "protein_names_uniprotkb": "Protein KRI1; KRR1-interacting protein 1", "protein_names_refseq": "Kri1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL308C)", "pathway_count": 1, "publication_count": 24, "publication_id_list": "11027267;14562095;14562106;15665377;17330950;17563356;18407956;19684113;19756047;19779198;20702584;21126336;21177495;22218487;23749301;24374639;27821475;30516470;32597660;33481703;33491328;33502312;7502583;9169873", "class_list": "", "function": "Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 16, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0N7", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005730 nucleolus;GO:0030686 90S preribosome", "go_biological_process": "GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "P42846-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P42939-1", "uniprot_id": "MVB12_YEAST", "mass": 11968.0, "length": 101, "protein_name": "Multivesicular body sorting factor 12", "gene_name": "MVB12", "organism": "Yeast", "refseq_name": "ubiquitin-binding ESCRT-I subunit protein MVB12", "refseq_ac": "NP_011722", "gene_names_uniprotkb": "MVB12; G7740", "gene_names_refseq": "MVB12", "protein_names_uniprotkb": "Multivesicular body sorting factor 12; 12 kDa multivesicular body sorting factor; ESCRT-I complex subunit MVB12", "protein_names_refseq": "ubiquitin-binding ESCRT-I subunit protein MVB12", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR206W)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "14562106;17135292;17215868;17287358;17322287;17442384;21177495;22814378;23749301;24374639;32597660;33481703;33491328;8904340;9169869", "class_list": "", "function": "Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Appears to be involved in cargo sorting and release of the ESCRT-I complex from the MVBs., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUY9", "ec_number_list": "", "go_molecular_function": "GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005768 endosome;GO:0005829 cytosol;GO:0031902 late endosome membrane;GO:0000813 ESCRT I complex", "go_biological_process": "GO:0031333 negative regulation of protein-containing complex assembly;GO:0032509 endosome transport via multivesicular body sorting pathway;GO:0006623 protein targeting to vacuole;GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:1904669 ATP export", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P42939-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P43565-1", "uniprot_id": "RIM15_YEAST", "mass": 196531.0, "length": 1770, "protein_name": "Serine/threonine-protein kinase RIM15", "gene_name": "RIM15", "organism": "Yeast", "refseq_name": "protein kinase RIM15", "refseq_ac": "NP_116620", "gene_names_uniprotkb": "RIM15; TAK1", "gene_names_refseq": "RIM15; TAK1", "protein_names_uniprotkb": "Serine/threonine-protein kinase RIM15; 2.7.11.1", "protein_names_refseq": "protein kinase RIM15", "tax_id": 559292, "disease": "thrombocytopenia (Disease Ontology:DOID:1588)", "pathway": " (sce:YFL033C); (R-SCE-2465910)", "pathway_count": 2, "publication_count": 23, "publication_id_list": "16308562;16751660;17330950;17563356;18407956;19779198;19795423;19823750;20471941;20489023;20702584;21078689;21126336;21177495;23749301;24374639;32597660;33229814;33481703;33491328;7670463;9111339;9744870", "class_list": "", "function": "Protein kinase that positively regulates proper entry into stationary phase of cells under nutrient starvation conditions. Involved in glycogen and trehalose accumulation, derepression of stress-induced genes, induction of thermotolerance and starvation resistance, and proper G1 cell cycle arrest. Also involved in the activation of a meiotic genes activation pathway. Phosphorylates IGO1 and IGO2, both involved in the TORC1 control of gene expression and chronological life span., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 4, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 4, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 4, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 83, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "D6VTJ8", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0034605 cellular response to heat;GO:0007346 regulation of mitotic cell cycle;GO:0034599 cellular response to oxidative stress", "synthesized_glycan_count": 0, "hit_score": 2.9, "record_id": "P43565-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P43586-1", "uniprot_id": "LOC1_YEAST", "mass": 23590.0, "length": 204, "protein_name": "60S ribosomal subunit assembly/export protein LOC1", "gene_name": "LOC1", "organism": "Yeast", "refseq_name": "Loc1p", "refseq_ac": "NP_116656", "gene_names_uniprotkb": "LOC1", "gene_names_refseq": "LOC1", "protein_names_uniprotkb": "60S ribosomal subunit assembly/export protein LOC1; Localization of ASH1 mRNA protein 1", "protein_names_refseq": "Loc1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YFR001W)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "11309412;11583614;14562095;14562106;15100437;15769876;16871394;17322287;19244342;19779198;23749301;24374639;33481703;33491328;7670463;8789262", "class_list": "", "function": "Required for efficient assembly and nuclear export of the 60S ribosomal subunit. Involved in asymmetric localization of ASH1 mRNA., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTN1", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0042802 identical protein binding;GO:0019843 rRNA binding;GO:0043022 ribosome binding;GO:0033592 RNA strand annealing activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0030687 preribosome, large subunit precursor;GO:0101031 protein folding chaperone complex", "go_biological_process": "GO:0000055 ribosomal large subunit export from nucleus;GO:0042273 ribosomal large subunit biogenesis;GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P43586-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P43605-1", "uniprot_id": "ECO1_YEAST", "mass": 31845.0, "length": 281, "protein_name": "N-acetyltransferase ECO1", "gene_name": "ECO1", "organism": "Yeast", "refseq_name": "Eco1p", "refseq_ac": "NP_116683", "gene_names_uniprotkb": "ECO1; CTF7", "gene_names_refseq": "CTF7; ECO1", "protein_names_uniprotkb": "N-acetyltransferase ECO1; 2.3.1.-; Chromosome transmission fidelity protein 7; Establishment of cohesion protein 1", "protein_names_refseq": "Eco1p", "tax_id": 559292, "disease": "lung cancer (Disease Ontology:DOID:1324); lung adenocarcinoma (Disease Ontology:DOID:3910); Roberts syndrome (Disease Ontology:DOID:5325); rheumatoid arthritis (Disease Ontology:DOID:7148)", "pathway": " (sce:YFR027W); (R-SCE-2468052)", "pathway_count": 2, "publication_count": 16, "publication_id_list": "11864574;12665596;15020404;15355977;15668154;18614053;21126336;21549314;23314252;23749301;24374639;32597660;7670463;8686381;9990855;9990856", "class_list": "", "function": "Required for establishment of sister chromatid cohesion during S phase but not for its further maintenance during G2 or M phases or for loading the cohesin complex onto DNA. Interacts with the three known alternate replication factor C (RFC) complexes, suggesting that these complexes have essential but redundant activity in cohesion establishment. Acts by acetylating the cohesin complex component SMC3. In vitro, possesses acetyltransferase activity where it can acetylate itself and components of the cohesin complex (MCD1, IRR1 and PDS5), but is unable to acetylate histones., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTQ7", "ec_number_list": "2.3.1.-", "go_molecular_function": "GO:0061733 protein-lysine-acetyltransferase activity;GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0016407 acetyltransferase activity", "go_cellular_component": "GO:0043596 nuclear replication fork;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000785 chromatin", "go_biological_process": "GO:0032200 telomere organization;GO:0006281 DNA repair;GO:0006260 DNA replication;GO:0006302 double-strand break repair;GO:0007076 mitotic chromosome condensation", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P43605-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P43612-1", "uniprot_id": "SA155_YEAST", "mass": 115002.0, "length": 1002, "protein_name": "SIT4-associating protein SAP155", "gene_name": "SAP155", "organism": "Yeast", "refseq_name": "Sap155p", "refseq_ac": "NP_116698", "gene_names_uniprotkb": "SAP155", "gene_names_refseq": "SAP155", "protein_names_uniprotkb": "SIT4-associating protein SAP155", "protein_names_refseq": "Sap155p", "tax_id": 559292, "disease": "", "pathway": " (sce:YFR040W); (R-SCE-204005)", "pathway_count": 2, "publication_count": 19, "publication_id_list": "11779790;14562095;14562106;15367655;15947196;17287358;17563356;18407956;19684113;19779198;21126336;23749301;24374639;32597660;33481703;33491328;7670463;8649382;8686379", "class_list": "", "function": "Positive regulator of protein phosphatase SIT4. Involved in directing expression of TOR-repressed genes and in dephosphorylation of NPR1 in response to nutrient starvation. Negatively modulates K(+) efflux of the cell by the Na(+)-K(+)/H(+) antiporter NHA1., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTS3;Q96VG4", "ec_number_list": "", "go_molecular_function": "GO:0019888 protein phosphatase regulator activity;GO:0019903 protein phosphatase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005684 U2-type spliceosomal complex", "go_biological_process": "GO:1903765 negative regulation of potassium ion export across plasma membrane;GO:0000082 G1/S transition of mitotic cell cycle;GO:0009966 regulation of signal transduction", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P43612-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P43636-1", "uniprot_id": "ALG2_YEAST", "mass": 58047.0, "length": 503, "protein_name": "Alpha-1,3/1,6-mannosyltransferase ALG2", "gene_name": "ALG2", "organism": "Yeast", "refseq_name": "GDP-Man:Man(1)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase", "refseq_ac": "NP_011450", "gene_names_uniprotkb": "ALG2", "gene_names_refseq": "ALG2", "protein_names_uniprotkb": "Alpha-1,3/1,6-mannosyltransferase ALG2; 2.4.1.132; 2.4.1.257; Asparagine-linked glycosylation protein 2; GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase; GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "protein_names_refseq": "GDP-Man:Man(1)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase", "tax_id": 559292, "disease": "congenital disorder of glycosylation Ii (Disease Ontology:DOID:0080561); congenital myasthenic syndrome 14 (Disease Ontology:DOID:0110669)", "pathway": " (sce:YGL065C); (R-SCE-446193)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "12684507;14562106;15044395;16878994;17287358;24374639;35136180;8400550;9169869;9234674;9290212", "class_list": "", "function": "Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "D6VU76", "ec_number_list": "2.4.1.132;2.4.1.257", "go_molecular_function": "GO:0000033 alpha-1,3-mannosyltransferase activity;GO:0000009 alpha-1,6-mannosyltransferase activity;GO:0004378 GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity;GO:0102704 GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity;GO:0033164 initiation-specific glycolipid 1,6-alpha-mannosyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0006488 dolichol-linked oligosaccharide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P43636-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P43639-1", "uniprot_id": "CSK2B_YEAST", "mass": 32265.0, "length": 278, "protein_name": "Casein kinase II subunit beta", "gene_name": "CKB1", "organism": "Yeast", "refseq_name": "casein kinase 2 regulatory subunit CKB1", "refseq_ac": "NP_011496", "gene_names_uniprotkb": "CKB1", "gene_names_refseq": "CKB1", "protein_names_uniprotkb": "Casein kinase II subunit beta; CK II beta", "protein_names_refseq": "casein kinase 2 regulatory subunit CKB1", "tax_id": 559292, "disease": "leiomyoma (Disease Ontology:DOID:127); myocardial infarction (Disease Ontology:DOID:5844)", "pathway": " (sce:YGL019W); (R-SCE-2514853); (R-SCE-6798695); (R-SCE-6804756); (R-SCE-8934903); (R-SCE-8948751)", "pathway_count": 6, "publication_count": 19, "publication_id_list": "12242279;14562106;15665377;17563356;18407956;19684113;19779198;19795423;19823750;21177495;22156209;22218487;22814378;24374639;33481703;33491328;7737972;8135547;9169869", "class_list": "", "function": "Regulatory subunit of casein kinase II/CK2 (By similarity). As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUB8;Q9URG5", "ec_number_list": "", "go_molecular_function": "GO:0019887 protein kinase regulator activity;GO:0030291 protein serine/threonine kinase inhibitor activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005956 protein kinase CK2 complex;GO:0032040 small-subunit processome;GO:0032545 CURI complex", "go_biological_process": "GO:0006974 DNA damage response;GO:0051726 regulation of cell cycle;GO:0006359 regulation of transcription by RNA polymerase III;GO:0000028 ribosomal small subunit assembly;GO:0006356 regulation of transcription by RNA polymerase I", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P43639-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P46677-1", "uniprot_id": "TAF1_YEAST", "mass": 120696.0, "length": 1066, "protein_name": "Transcription initiation factor TFIID subunit 1", "gene_name": "TAF1", "organism": "Yeast", "refseq_name": "histone acetyltransferase", "refseq_ac": "NP_011790", "gene_names_uniprotkb": "TAF1; G9374; TAF130; TAF145", "gene_names_refseq": "KAT4; TAF130; TAF145; TAF1", "protein_names_uniprotkb": "Transcription initiation factor TFIID subunit 1; 2.3.1.48; TAFII-130; TAFII-145; TBP-associated factor 145 kDa; TBP-associated factor 1", "protein_names_refseq": "histone acetyltransferase", "tax_id": 559292, "disease": "syndromic X-linked intellectual disability (Disease Ontology:DOID:0060309); X-linked dystonia-parkinsonism (Disease Ontology:DOID:0090057)", "pathway": " (sce:YGR274C); (R-SCE-674695); (R-SCE-73776); (R-SCE-73779); (R-SCE-75953); (R-SCE-76042)", "pathway_count": 6, "publication_count": 20, "publication_id_list": "10788514;12093743;12138208;12516863;14562095;14562106;18407956;20489023;23749301;24374639;32597660;33229814;33481703;33491328;33502312;7667272;7935765;8980232;9133740;9169869", "class_list": "", "function": "Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 21, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 2, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6VV51", "ec_number_list": "2.7.7.6;2.7.11.23;5.6.2.3;2.3.1.48;5.6.2.4;2.3.1.-", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0003682 chromatin binding;GO:0046982 protein heterodimerization activity;GO:0017025 TBP-class protein binding;GO:0004402 histone acetyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005669 transcription factor TFIID complex", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006366 transcription by RNA polymerase II;GO:0051123 RNA polymerase II preinitiation complex assembly", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "P46677-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P46948-1", "uniprot_id": "RRP41_YEAST", "mass": 27561.0, "length": 246, "protein_name": "Exosome complex component SKI6", "gene_name": "SKI6", "organism": "Yeast", "refseq_name": "exosome non-catalytic core subunit SKI6", "refseq_ac": "NP_011711", "gene_names_uniprotkb": "SKI6; ECM20; G7587; RRP41", "gene_names_refseq": "ECM20; RRP41; SKI6", "protein_names_uniprotkb": "Exosome complex component SKI6; Extracellular mutant protein 20; Ribosomal RNA-processing protein 41; Superkiller protein 6", "protein_names_refseq": "exosome non-catalytic core subunit SKI6", "tax_id": 559292, "disease": "developmental disorder of mental health (Disease Ontology:DOID:0060037)", "pathway": " (sce:YGR195W); (R-SCE-429958); (R-SCE-450385); (R-SCE-450513); (R-SCE-6791226)", "pathway_count": 5, "publication_count": 14, "publication_id_list": "10465791;14562095;14562106;17173052;17174896;17322287;19879841;24374639;30181345;32597660;33491328;7502584;9169869;9390555", "class_list": "", "function": "Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and in RNA surveillance pathways, preventing translation of aberrant mRNAs. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. SKI6 is part of the hexameric ring of RNase PH domain-containing subunits proposed to form a central channel which threads RNA substrates for degradation., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUX7", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0000176 nuclear exosome (RNase complex);GO:0000177 cytoplasmic exosome (RNase complex)", "go_biological_process": "GO:0071028 nuclear mRNA surveillance;GO:0034473 U1 snRNA 3'-end processing;GO:0034476 U5 snRNA 3'-end processing;GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay;GO:0006396 RNA processing", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P46948-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P46957-1", "uniprot_id": "DPOD2_YEAST", "mass": 55296.0, "length": 487, "protein_name": "DNA polymerase delta small subunit", "gene_name": "POL31", "organism": "Yeast", "refseq_name": "DNA-directed DNA polymerase delta subunit POL31", "refseq_ac": "NP_012539", "gene_names_uniprotkb": "POL31; HUS2; HYS2; J1427; SDP5; YJR83.7", "gene_names_refseq": "HUS2; HYS2; POL31; SDP5", "protein_names_uniprotkb": "DNA polymerase delta small subunit; 2.7.7.7; Hydroxyurea-sensitive protein 2", "protein_names_refseq": "DNA-directed DNA polymerase delta subunit POL31", "tax_id": 559292, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (sce:YJR006W); (R-SCE-69166); (R-SCE-69183)", "pathway_count": 3, "publication_count": 14, "publication_id_list": "11568188;14562106;18407956;20190278;21126336;22814378;23749301;24374639;32597660;33491328;7567461;8641269;9421503;9677405", "class_list": "", "function": "DNA polymerase delta (DNA polymerase III) participates in chromosomal DNA replication. It is required during synthesis of the leading and lagging DNA strands at the replication fork and binds at/or near replication origins and moves along DNA with the replication fork. It has 3'-5' proofreading exonuclease activity that correct errors arising during DNA replication. It is also involved in DNA synthesis during DNA repair., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VWI1", "ec_number_list": "2.7.7.7;3.1.26.4;2.7.7.49;3.4.23.-;2.7.7.-;3.1.11.-;3.1.-.-", "go_molecular_function": "GO:0003887 DNA-directed DNA polymerase activity;GO:0003677 DNA binding", "go_cellular_component": "GO:0043625 delta DNA polymerase complex;GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0016035 zeta DNA polymerase complex", "go_biological_process": "GO:0006278 RNA-templated DNA biosynthetic process;GO:0006271 DNA strand elongation involved in DNA replication;GO:0006272 leading strand elongation;GO:0006273 lagging strand elongation;GO:0006284 base-excision repair", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P46957-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P47027-1", "uniprot_id": "DPB11_YEAST", "mass": 87241.0, "length": 764, "protein_name": "DNA replication regulator DPB11", "gene_name": "DPB11", "organism": "Yeast", "refseq_name": "protein kinase activating protein DPB11", "refseq_ac": "NP_012445", "gene_names_uniprotkb": "DPB11; J0918", "gene_names_refseq": "DPB11", "protein_names_uniprotkb": "DNA replication regulator DPB11", "protein_names_refseq": "protein kinase activating protein DPB11", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL090C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10097122;12730134;14562106;18407956;21126336;23749301;24374639;33481703;33491328;7483841;8524850;8641269;9742127", "class_list": "", "function": "Has a role in the initiation of DNA replication. Required at S-phase checkpoint. Required for the association of PSF1 with origins. Also required for the proper activation of RAD53 in response to DNA damage and replication blocks. Multicopy suppressor of DPB2 mutation. Overexpression restores the growth defect conferred by POL2 mutation., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 18, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VW94;Q05712", "ec_number_list": "", "go_molecular_function": "GO:0030295 protein kinase activator activity;GO:0070182 DNA polymerase binding;GO:0140463 chromatin-protein adaptor activity", "go_cellular_component": "GO:0031261 DNA replication preinitiation complex;GO:0005634 nucleus;GO:0005657 replication fork;GO:0070532 BRCA1-B complex", "go_biological_process": "GO:0000076 DNA replication checkpoint signaling;GO:0007095 mitotic G2 DNA damage checkpoint signaling;GO:0006270 DNA replication initiation;GO:0000725 recombinational repair;GO:0000727 double-strand break repair via break-induced replication", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P47027-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P47049-1", "uniprot_id": "UBX6_YEAST", "mass": 45016.0, "length": 396, "protein_name": "UBX domain-containing protein 6", "gene_name": "UBX6", "organism": "Yeast", "refseq_name": "Ubx6p", "refseq_ac": "NP_012487", "gene_names_uniprotkb": "UBX6; J1164", "gene_names_refseq": "CUI2; UBX6", "protein_names_uniprotkb": "UBX domain-containing protein 6", "protein_names_refseq": "Ubx6p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJL048C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562106;15258615;17322287;18407956;19779198;20489023;23749301;24374639;33491328;8641269", "class_list": "", "function": "Involved in CDC48-dependent protein degradation through the ubiquitin/proteasome pathway., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWD5", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0006511 ubiquitin-dependent protein catabolic process;GO:0036503 ERAD pathway;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P47049-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P47074-1", "uniprot_id": "MAD3_YEAST", "mass": 59521.0, "length": 515, "protein_name": "Spindle assembly checkpoint component MAD3", "gene_name": "MAD3", "organism": "Yeast", "refseq_name": "Mad3p", "refseq_ac": "NP_012521", "gene_names_uniprotkb": "MAD3; J1341", "gene_names_refseq": "MAD3", "protein_names_uniprotkb": "Spindle assembly checkpoint component MAD3; Mitotic MAD3 protein", "protein_names_refseq": "Mad3p", "tax_id": 559292, "disease": "mosaic variegated aneuploidy syndrome 1 (Disease Ontology:DOID:0080141); tongue carcinoma (Disease Ontology:DOID:0080641); pancreatic cancer (Disease Ontology:DOID:1793); gallbladder cancer (Disease Ontology:DOID:3121); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (sce:YJL013C); (R-SCE-141430)", "pathway_count": 2, "publication_count": 16, "publication_id_list": "10704439;11726501;14562106;15665377;15879521;17227844;17504936;17563356;18407956;19779198;22218487;23749301;24374639;33481703;33491328;8641269", "class_list": "", "function": "Component of the spindle assembly checkpoint which is a feedback control that prevents cells with incompletely assembled spindles from leaving mitosis. Component of the mitotic checkpoint complex (MCC) which inhibits the ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) by preventing its activation by CDC20., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWG4", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0033597 mitotic checkpoint complex", "go_biological_process": "GO:0044774 mitotic DNA integrity checkpoint signaling;GO:0051301 cell division;GO:0051754 meiotic sister chromatid cohesion, centromeric;GO:0007094 mitotic spindle assembly checkpoint signaling;GO:1902499 positive regulation of protein autoubiquitination", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P47074-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P47076-1", "uniprot_id": "RPC9_YEAST", "mass": 18596.0, "length": 161, "protein_name": "DNA-directed RNA polymerase III subunit RPC9", "gene_name": "RPC17", "organism": "Yeast", "refseq_name": "DNA-directed RNA polymerase III subunit RPC17", "refseq_ac": "NP_012523", "gene_names_uniprotkb": "RPC17; J1349", "gene_names_refseq": "RPC17", "protein_names_uniprotkb": "DNA-directed RNA polymerase III subunit RPC9; RNA polymerase III subunit C17; RNA polymerase III subunit C9", "protein_names_refseq": "DNA-directed RNA polymerase III subunit RPC17", "tax_id": 559292, "disease": "sciatic neuropathy (Disease Ontology:DOID:11446)", "pathway": " (sce:YJL011C); (R-SCE-76061); (R-SCE-76066)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10384303;10611227;12482973;14562095;14562106;16818233;17322287;22814378;24374639;33491328;8641269", "class_list": "", "function": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. The RPC25/RPC8-RPC17/RPC9 subcomplex may bind Pol III transcripts emerging from the adjacent exit pore during elongation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWG6", "ec_number_list": "", "go_molecular_function": "GO:0000166 nucleotide binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005666 RNA polymerase III complex", "go_biological_process": "GO:0042797 tRNA transcription by RNA polymerase III;GO:0006383 transcription by RNA polymerase III;GO:0006386 termination of RNA polymerase III transcription;GO:0006384 transcription initiation at RNA polymerase III promoter", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P47076-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P47104-1", "uniprot_id": "RAV1_YEAST", "mass": 154933.0, "length": 1357, "protein_name": "Regulator of V-ATPase in vacuolar membrane protein 1", "gene_name": "RAV1", "organism": "Yeast", "refseq_name": "Rav1p", "refseq_ac": "NP_012567", "gene_names_uniprotkb": "RAV1; J1590; SOI3", "gene_names_refseq": "RAV1; SOI3", "protein_names_uniprotkb": "Regulator of V-ATPase in vacuolar membrane protein 1; Suppression of the onset of impotence protein 3", "protein_names_refseq": "Rav1p", "tax_id": 559292, "disease": "autosomal dominant nonsyndromic deafness 71 (Disease Ontology:DOID:0080267); developmental and epileptic encephalopathy 81 (Disease Ontology:DOID:0112217)", "pathway": " (sce:YJR033C)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "11283612;11844802;14562106;15090613;15665377;18407956;19779198;19795423;19823750;21126336;22218487;23749301;24374639;32597660;33481703;33491328;7668047;8619316;8641269", "class_list": "", "function": "Component of the RAVE complex, which is required for stable assembly of the vacuolar ATPase complex V-ATPase under many conditions. Required for transport between the early endosome and the late endosome/prevacuolar compartment (PVC), suggesting that assembly of vacuolar ATPase at the early endosome is required for transport from the early endosome to the PVC., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWK6", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0043291 RAVE complex;GO:0005737 cytoplasm;GO:0012505 endomembrane system", "go_biological_process": "GO:0015031 protein transport;GO:0045022 early endosome to late endosome transport;GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly;GO:0043254 regulation of protein-containing complex assembly;GO:0007035 vacuolar acidification", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P47104-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P47113-1", "uniprot_id": "BFA1_YEAST", "mass": 66086.0, "length": 574, "protein_name": "Mitotic check point protein BFA1", "gene_name": "BFA1", "organism": "Yeast", "refseq_name": "Bfa1p", "refseq_ac": "NP_012587", "gene_names_uniprotkb": "BFA1; J1667", "gene_names_refseq": "BFA1; IBD1", "protein_names_uniprotkb": "Mitotic check point protein BFA1; Cell cycle arrest protein BFA1", "protein_names_refseq": "Bfa1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR053W)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "10220406;11493673;11733064;14562106;17967947;19779198;20702584;21126336;22031224;22253605;23749301;24374639;24850890;27159239;32597660;33481703;33491328;7668047;8641269", "class_list": "", "function": "Part of a checkpoint which monitors spindle integrity and prevents premature exit from mitosis. This cell-cycle arrest depends upon inhibition of the G protein TEM1 by the BFA1/BUB2 complex., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 50, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWM4", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005092 GDP-dissociation inhibitor activity", "go_cellular_component": "GO:0000922 spindle pole;GO:0005816 spindle pole body;GO:1990334 Bfa1-Bub2 complex;GO:0044732 mitotic spindle pole body", "go_biological_process": "GO:0051301 cell division;GO:0001100 negative regulation of exit from mitosis;GO:0031578 mitotic spindle orientation checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P47113-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P47120-1", "uniprot_id": "DOHH_YEAST", "mass": 36165.0, "length": 325, "protein_name": "Deoxyhypusine hydroxylase", "gene_name": "LIA1", "organism": "Yeast", "refseq_name": "deoxyhypusine monooxygenase", "refseq_ac": "NP_012604", "gene_names_uniprotkb": "LIA1; J1814; MMD1", "gene_names_refseq": "LIA1; MMD1", "protein_names_uniprotkb": "Deoxyhypusine hydroxylase; 1.14.99.29; DOHH; Deoxyhypusine dioxygenase; Deoxyhypusine monooxygenase; Ligand of eIF5A protein 1", "protein_names_refseq": "deoxyhypusine monooxygenase", "tax_id": 559292, "disease": "pulmonary hypertension (Disease Ontology:DOID:6432)", "pathway": " (sce:YJR070C); (R-SCE-204626)", "pathway_count": 2, "publication_count": 17, "publication_id_list": "14562095;14562106;16371467;17330950;17563356;18407956;19779198;19956996;24374639;32597660;33481703;33491328;34965436;8641269;8840504;8962070;9298649", "class_list": "", "function": "Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor., [UniProtKB, PubMed, PubMed, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 11, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWP1", "ec_number_list": "1.14.99.29", "go_molecular_function": "GO:0019135 deoxyhypusine monooxygenase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0000226 microtubule cytoskeleton organization;GO:0008612 peptidyl-lysine modification to peptidyl-hypusine", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P47120-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P47136-1", "uniprot_id": "BUD4_YEAST", "mass": 164486.0, "length": 1447, "protein_name": "Bud site selection protein 4", "gene_name": "BUD4", "organism": "Yeast", "refseq_name": "Bud4p", "refseq_ac": "NP_012625", "gene_names_uniprotkb": "BUD4; J1905", "gene_names_refseq": "BUD4", "protein_names_uniprotkb": "Bud site selection protein 4", "protein_names_refseq": "Bud4p", "tax_id": 559292, "disease": "", "pathway": " (sce:YJR092W)", "pathway_count": 1, "publication_count": 28, "publication_id_list": "11875433;12176366;12221111;12446742;14562095;14562106;14574415;15665377;15784684;17460121;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21177495;22218487;23749301;24374639;24909858;30516470;32597660;33481703;33491328;8641269;8707826", "class_list": "", "function": "Required for establishment of the axial budding pattern in haploid cells. Cooperates with other bud site selection proteins to recognize a spatial landmark during mitosis and they subsequently become a landmark for downstream polarity establishment factors that coordinate axial budding and cytokinesis. Involved in the septin organization at the bud neck., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 88, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWR0", "ec_number_list": "", "go_molecular_function": "GO:0005525 GTP binding", "go_cellular_component": "GO:0000142 cellular bud neck contractile ring;GO:0005621 cellular bud scar;GO:0005935 cellular bud neck", "go_biological_process": "GO:0031106 septin ring organization;GO:0007120 axial cellular bud site selection;GO:0097271 protein localization to bud neck", "synthesized_glycan_count": 0, "hit_score": 2.9, "record_id": "P47136-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P48234-1", "uniprot_id": "NOL10_YEAST", "mass": 81734.0, "length": 707, "protein_name": "Ribosome biogenesis protein ENP2", "gene_name": "ENP2", "organism": "Yeast", "refseq_name": "ribosome biosynthesis protein ENP2", "refseq_ac": "NP_011661", "gene_names_uniprotkb": "ENP2; G6623", "gene_names_refseq": "ENP2", "protein_names_uniprotkb": "Ribosome biogenesis protein ENP2; Essential nuclear protein 2", "protein_names_refseq": "ribosome biosynthesis protein ENP2", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR145W)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "12150911;14690591;15590835;16429126;16544271;17287358;17330950;17563356;18407956;19684113;19779198;20702584;21126336;21177495;22218487;23749301;24374639;32597660;33481703;33491328;8585325;9169869", "class_list": "", "function": "May be involved in rRNA-processing and ribosome biosynthesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUS5", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005730 nucleolus;GO:0030686 90S preribosome;GO:0032040 small-subunit processome", "go_biological_process": "GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0042274 ribosomal small subunit biogenesis;GO:0030490 maturation of SSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "P48234-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P48415-1", "uniprot_id": "SEC16_YEAST", "mass": 241696.0, "length": 2195, "protein_name": "COPII coat assembly protein SEC16", "gene_name": "SEC16", "organism": "Yeast", "refseq_name": "COPII coat assembly protein SEC16", "refseq_ac": "NP_015240", "gene_names_uniprotkb": "SEC16; LPF1W", "gene_names_refseq": "LPF1; SEC16", "protein_names_uniprotkb": "COPII coat assembly protein SEC16; Protein transport protein SEC16", "protein_names_refseq": "COPII coat assembly protein SEC16", "tax_id": 559292, "disease": "obesity (Disease Ontology:DOID:9970)", "pathway": " (sce:YPL085W)", "pathway_count": 1, "publication_count": 33, "publication_id_list": "10712514;11694599;12235121;14562095;14562106;15665377;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;2188733;22218487;22814378;23273919;23749301;24374639;30516470;32597660;33229814;33481703;33491328;7593161;7593162;9023343;9169875;9325247;9880808", "class_list": "", "function": "Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 17, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 17, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 17, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 148, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 17, "binding_glycan_count": 0, "secondary_ac_list": "D6W3T2;Q02822", "ec_number_list": "", "go_molecular_function": "GO:0043495 protein-membrane adaptor activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0012507 ER to Golgi transport vesicle membrane;GO:0070971 endoplasmic reticulum exit site", "go_biological_process": "GO:0015031 protein transport;GO:0016236 macroautophagy;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0048208 COPII vesicle coating;GO:0070973 protein localization to endoplasmic reticulum exit site", "synthesized_glycan_count": 0, "hit_score": 5.2, "record_id": "P48415-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P48524-1", "uniprot_id": "BUL1_YEAST", "mass": 109174.0, "length": 976, "protein_name": "Ubiquitin ligase-binding protein BUL1", "gene_name": "BUL1", "organism": "Yeast", "refseq_name": "ubiquitin-ubiquitin ligase BUL1", "refseq_ac": "NP_014002", "gene_names_uniprotkb": "BUL1; DAG1; RDS1; SMM2; YM8021.01C; YM8156.17C", "gene_names_refseq": "BUL1; DAG1; RDS1; SMM2", "protein_names_uniprotkb": "Ubiquitin ligase-binding protein BUL1; Respiration deficiency suppressor 1", "protein_names_refseq": "ubiquitin-ubiquitin ligase BUL1", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR275C)", "pathway_count": 1, "publication_count": 34, "publication_id_list": "10958669;11352928;11500494;12821147;14560004;14562095;14562106;15020711;15190065;15247235;15665377;16864574;17287358;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22218487;22966204;23749301;24374639;28270554;32597660;33229814;33481703;33491328;34965436;8668140;9169872;9931424", "class_list": "", "function": "Component of a RSP5 ubiquitin ligase complex which specifies polyubiquitination and intracellular trafficking of the general amino acid permease GAP1 as well as other permeases such as PMA1. The RSP5-BUL1/2 complex is also necessary for the heat-shock element (HSE)-mediated gene expression, nitrogen starvation GLN3-dependent transcription and pressure-induced differential regulation of the 2 tryptophan permeases TAT1 and TAT2., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 36, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6W0A2", "ec_number_list": "", "go_molecular_function": "GO:0034450 ubiquitin-ubiquitin ligase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0000151 ubiquitin ligase complex", "go_biological_process": "GO:2000397 positive regulation of ubiquitin-dependent endocytosis;GO:0009749 response to glucose;GO:0000209 protein polyubiquitination;GO:0006513 protein monoubiquitination;GO:0070086 ubiquitin-dependent endocytosis", "synthesized_glycan_count": 0, "hit_score": 3.9, "record_id": "P48524-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P48743-1", "uniprot_id": "RFX1_YEAST", "mass": 90584.0, "length": 811, "protein_name": "RFX-like DNA-binding protein RFX1", "gene_name": "RFX1", "organism": "Yeast", "refseq_name": "Rfx1p", "refseq_ac": "NP_013277", "gene_names_uniprotkb": "RFX1; CRT1; L9470.18", "gene_names_refseq": "CRT1; RFX1", "protein_names_uniprotkb": "RFX-like DNA-binding protein RFX1", "protein_names_refseq": "Rfx1p", "tax_id": 559292, "disease": "visceral heterotaxy (Disease Ontology:DOID:0050545)", "pathway": " (sce:YLR176C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "14562106;18407956;19779198;20190278;21126336;23749301;24374639;32597660;33481703;33491328;9169871", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VYI0", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P48743-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P48813-1", "uniprot_id": "GNP1_YEAST", "mass": 73598.0, "length": 663, "protein_name": "High-affinity glutamine permease", "gene_name": "GNP1", "organism": "Yeast", "refseq_name": "glutamine permease GNP1", "refseq_ac": "NP_010796", "gene_names_uniprotkb": "GNP1; D9719.14", "gene_names_refseq": "GNP1", "protein_names_uniprotkb": "High-affinity glutamine permease", "protein_names_refseq": "glutamine permease GNP1", "tax_id": 559292, "disease": "retinitis pigmentosa 68 (Disease Ontology:DOID:0110374); sensorineural hearing loss (Disease Ontology:DOID:10003); blindness (Disease Ontology:DOID:1432)", "pathway": " (sce:YDR508C)", "pathway_count": 1, "publication_count": 28, "publication_id_list": "10467005;10654085;11875433;12872131;14562106;14576278;15665377;16847258;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22106047;22218487;23749301;24374639;30516470;32597660;33481703;33491328;8660458;9169867", "class_list": "", "function": "High affinity transport of glutamine. Also transports Leu, Ser, Thr, Cys, Met and Asn., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 20, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTD0", "ec_number_list": "", "go_molecular_function": "GO:0015193 L-proline transmembrane transporter activity;GO:0015171 amino acid transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0031966 mitochondrial membrane;GO:0071944 cell periphery", "go_biological_process": "GO:0055085 transmembrane transport;GO:0006865 amino acid transport;GO:0003333 amino acid transmembrane transport;GO:0090156 intracellular sphingolipid homeostasis;GO:0098718 serine import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 2.9, "record_id": "P48813-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P48836-1", "uniprot_id": "VATG_YEAST", "mass": 12713.0, "length": 114, "protein_name": "V-type proton ATPase subunit G", "gene_name": "VMA10", "organism": "Yeast", "refseq_name": "H(+)-transporting V1 sector ATPase subunit G", "refseq_ac": "NP_011905", "gene_names_uniprotkb": "VMA10; YHR039BC; YHR039C-B", "gene_names_refseq": "VMA10; YHR039C-B", "protein_names_uniprotkb": "V-type proton ATPase subunit G; V-ATPase 13 kDa subunit; V-ATPase subunit G; Vacuolar proton pump subunit G", "protein_names_refseq": "H(+)-transporting V1 sector ATPase subunit G", "tax_id": 559292, "disease": "", "pathway": " (sce:YHR039C-A); (R-SCE-1222556); (R-SCE-77387); (R-SCE-917977); (R-SCE-9639288)", "pathway_count": 5, "publication_count": 11, "publication_id_list": "14562106;19795423;19823750;22814378;24374639;25971514;27295975;33481703;33491328;7775427;8091229", "class_list": "", "function": "Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:7775427). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (PubMed:7775427)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3DKY7", "ec_number_list": "", "go_molecular_function": "GO:0046961 proton-transporting ATPase activity, rotational mechanism", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0048388 endosomal lumen acidification;GO:0007035 vacuolar acidification;GO:1902600 proton transmembrane transport;GO:0061795 Golgi lumen acidification", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P48836-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P48837-1", "uniprot_id": "NUP57_YEAST", "mass": 57499.0, "length": 541, "protein_name": "Nucleoporin NUP57", "gene_name": "NUP57", "organism": "Yeast", "refseq_name": "FG-nucleoporin NUP57", "refseq_ac": "NP_011634", "gene_names_uniprotkb": "NUP57; G6320", "gene_names_refseq": "NUP57", "protein_names_uniprotkb": "Nucleoporin NUP57; Nuclear pore protein NUP57", "protein_names_refseq": "FG-nucleoporin NUP57", "tax_id": 559292, "disease": "dystonia 37, early-onset with striatal lesions (Disease Ontology:DOID:0060956)", "pathway": " (sce:YGR119C)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "10684247;11387327;11689687;12604785;12791264;14562106;15039779;17322287;17563356;18407956;19684113;19779198;23749301;24374639;32597660;33491328;7828598;8905931;9017593;9046098;9169869;9725905", "class_list": "", "function": "Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope (GSP1 and GSP2 GTPases associated predominantly with GTP in the nucleus, with GDP in the cytoplasm). NUP57 plays an important role in several nuclear transport pathways including poly(A)+ RNA, tRNA, and pre-ribosome transport., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUQ0", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0017056 structural constituent of nuclear pore", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005643 nuclear pore;GO:0031965 nuclear membrane;GO:0044613 nuclear pore central transport channel", "go_biological_process": "GO:0006999 nuclear pore organization;GO:0006913 nucleocytoplasmic transport;GO:0051028 mRNA transport;GO:0036228 protein localization to nuclear inner membrane;GO:0006607 NLS-bearing protein import into nucleus", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "P48837-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P50091-1", "uniprot_id": "PEX21_YEAST", "mass": 33050.0, "length": 288, "protein_name": "Peroxisomal protein PEX21", "gene_name": "PEX21", "organism": "Yeast", "refseq_name": "Pex21p", "refseq_ac": "NP_011755", "gene_names_uniprotkb": "PEX21; G8593", "gene_names_refseq": "PEX21", "protein_names_uniprotkb": "Peroxisomal protein PEX21; Peroxin-21", "protein_names_refseq": "Pex21p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR239C)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "11606420;12167700;12204379;14562095;17322287;17451428;18407956;23812376;24374639;33481703;33491328;8701610;9090057;9169869;9864360", "class_list": "", "function": "Receptor that mediates peroxisomal import of proteins containing a C-terminal PTS2-type peroxisomal targeting signal via its interaction with PEX7 (PubMed:12167700, PubMed:23812376, PubMed:9864360). Interaction with PEX7 only takes place when PEX7 is associated with cargo proteins containing a PTS2 peroxisomal targeting signal (By similarity). PEX7 along with PTS2-containing cargo proteins are then translocated through the PEX13-PEX14 docking complex together with PEX21 (PubMed:23812376). Acts as an activator of the seryl-tRNA synthetase SES1 by increasing its binding to tRNA (PubMed:12204379, PubMed:17451428)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VV19;O11855;Q6Q597", "ec_number_list": "", "go_molecular_function": "GO:0140597 protein carrier chaperone", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005777 peroxisome;GO:0005829 cytosol", "go_biological_process": "GO:0016558 protein import into peroxisome matrix", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P50091-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P50110-1", "uniprot_id": "SAM37_YEAST", "mass": 37493.0, "length": 327, "protein_name": "Sorting assembly machinery 37 kDa subunit", "gene_name": "SAM37", "organism": "Yeast", "refseq_name": "SAM complex subunit SAM37", "refseq_ac": "NP_013776", "gene_names_uniprotkb": "SAM37; MAS37; PET3027; TOM37; YM9796.13C", "gene_names_refseq": "MAS37; PET3027; SAM37; TOM37", "protein_names_uniprotkb": "Sorting assembly machinery 37 kDa subunit; MAS37 protein; Mitochondrial 37 kDa outer membrane protein", "protein_names_refseq": "SAM complex subunit SAM37", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR060C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "12891361;14562106;14570913;15590639;16823961;17322287;24374639;33481703;33491328;7698990;9169872", "class_list": "", "function": "Component of the mitochondrial outer membrane sorting assembly machinery (SAM or TOB) complex, which is required for the sorting of proteins with complicated topology, such as beta-barrel proteins, to the mitochondrial outer membrane after import by the TOM complex., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZN4", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0001401 SAM complex;GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0045040 protein insertion into mitochondrial outer membrane;GO:0015914 phospholipid transport;GO:0030150 protein import into mitochondrial matrix;GO:0070096 mitochondrial outer membrane translocase complex assembly", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P50110-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P50111-1", "uniprot_id": "ZDS1_YEAST", "mass": 103358.0, "length": 915, "protein_name": "Protein ZDS1", "gene_name": "ZDS1", "organism": "Yeast", "refseq_name": "Zds1p", "refseq_ac": "NP_014000", "gene_names_uniprotkb": "ZDS1; CES1; CKM1; HST1; NRC1; OSS1; STM2; YM8156.15C", "gene_names_refseq": "CES1; CKM1; NRC1; OSS1; ZDS1", "protein_names_uniprotkb": "Protein ZDS1; Protein NRC1; RT2GS1", "protein_names_refseq": "Zds1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR273C)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "11134339;11489916;12704202;14562106;15619606;16157662;17287358;17330950;19779198;23749301;24374639;24909858;32597660;33481703;33491328;8647431;8816439;8836740;8918228;9169872", "class_list": "", "function": "Has a role in establishing cell polarity. Together with cAMP-dependent protein kinase regulatory subunit BCY1, provides a negative feedback control on the cell wall integrity-signaling pathway by acting as a negative regulator of MAP kinase SLT2/MPK1. In heat-stressed cells appears to play a role in localizing BCY1 to the cytoplasm. Seems to interact with, and down-regulate, CDC42. Also acts as a suppressor of PKC1. May act as an integration point for distinct signaling pathways helping to maintain a balance among these different pathways., [UniProtKB]; When associated with DBP5, GFD1 and nucleoporins at the cytosolic fibrils of the nuclear pore complex, is required for mRNA export form the nucleus., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 23, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0A0;P41373", "ec_number_list": "", "go_molecular_function": "GO:0004864 protein phosphatase inhibitor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0000131 incipient cellular bud site;GO:0005934 cellular bud tip;GO:0005935 cellular bud neck", "go_biological_process": "GO:0006406 mRNA export from nucleus;GO:0010971 positive regulation of G2/M transition of mitotic cell cycle;GO:0032880 regulation of protein localization;GO:0030010 establishment of cell polarity;GO:0031507 heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P50111-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P50942-1", "uniprot_id": "INP52_YEAST", "mass": 133331.0, "length": 1183, "protein_name": "Polyphosphatidylinositol phosphatase INP52", "gene_name": "INP52", "organism": "Yeast", "refseq_name": "phosphatidylinositol-3-/phosphoinositide 5-phosphatase INP52", "refseq_ac": "NP_014293", "gene_names_uniprotkb": "INP52; N2160; SJL2", "gene_names_refseq": "INP52; SJL2", "protein_names_uniprotkb": "Polyphosphatidylinositol phosphatase INP52; Synaptojanin-like protein 2", "protein_names_refseq": "phosphatidylinositol-3-/phosphoinositide 5-phosphatase INP52", "tax_id": 559292, "disease": "early-onset Parkinson's disease (Disease Ontology:DOID:0060894); Parkinson's disease 20 (Disease Ontology:DOID:0060898); developmental and epileptic encephalopathy 53 (Disease Ontology:DOID:0080464); Down syndrome (Disease Ontology:DOID:14250); Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (sce:YNL106C); (R-SCE-1660499); (R-SCE-1855183); (R-SCE-1855204)", "pathway_count": 4, "publication_count": 34, "publication_id_list": "10224048;10625610;10962003;11094088;11311145;12606027;14562095;15169871;15665377;15691741;15798181;16406366;17330950;17452534;17563356;18407956;19684113;19779198;19795423;19823750;21126336;21177495;22218487;23749301;24374639;32597660;33481703;33491328;8701612;9090055;9169873;9265642;9560389;9788876", "class_list": "", "function": "Dephosphorylates a number of phosphatidylinositols (PIs) like phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), but also phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4-phosphate (PtdIns(4)P), and phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Controls the cellular levels and subcellular distribution of phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-bisphosphate. Specifically functions within the early endocytic pathway and actin organization., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 39, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W174", "ec_number_list": "3.1.3.36;3.1.3.-", "go_molecular_function": "GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity;GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity;GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity;GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity;GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0030479 actin cortical patch;GO:0043332 mating projection tip", "go_biological_process": "GO:0006897 endocytosis;GO:0015031 protein transport;GO:0046856 phosphatidylinositol dephosphorylation", "synthesized_glycan_count": 0, "hit_score": 3.5, "record_id": "P50942-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P51534-1", "uniprot_id": "SHE4_YEAST", "mass": 89553.0, "length": 789, "protein_name": "SWI5-dependent HO expression protein 4", "gene_name": "SHE4", "organism": "Yeast", "refseq_name": "She4p", "refseq_ac": "NP_014678", "gene_names_uniprotkb": "SHE4; OR26.26", "gene_names_refseq": "DIM1; SHE4", "protein_names_uniprotkb": "SWI5-dependent HO expression protein 4", "protein_names_refseq": "She4p", "tax_id": 559292, "disease": "myofibrillar myopathy 11 (Disease Ontology:DOID:0081338); cataract 43 (Disease Ontology:DOID:0110259)", "pathway": " (sce:YOR035C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562106;18407956;24374639;27888470;8625407;9169874", "class_list": "", "function": "Required for mother cell-specific ho expression. Might be required for the transport of factors (such as ASH1) that promote HO repression from the mother cell into its bud., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2A2", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0017022 myosin binding;GO:0051879 Hsp90 protein binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0030036 actin cytoskeleton organization;GO:0006457 protein folding;GO:0008298 intracellular mRNA localization;GO:0007533 mating type switching", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P51534-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53096-1", "uniprot_id": "HOS2_YEAST", "mass": 51455.0, "length": 452, "protein_name": "Probable histone deacetylase HOS2", "gene_name": "HOS2", "organism": "Yeast", "refseq_name": "histone deacetylase HOS2", "refseq_ac": "NP_011321", "gene_names_uniprotkb": "HOS2; G1330", "gene_names_refseq": "HOS2; RTL1", "protein_names_uniprotkb": "Probable histone deacetylase HOS2; 3.5.1.98", "protein_names_refseq": "histone deacetylase HOS2", "tax_id": 559292, "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); intrahepatic cholestasis of pregnancy (Disease Ontology:DOID:0070227); prostate carcinoma (Disease Ontology:DOID:10286); impotence (Disease Ontology:DOID:1875); ovarian cancer (Disease Ontology:DOID:2394); endometrial carcinoma (Disease Ontology:DOID:2871); endometriosis (Disease Ontology:DOID:289); acute kidney failure (Disease Ontology:DOID:3021); high grade glioma (Disease Ontology:DOID:3070); lung non-small cell carcinoma (Disease Ontology:DOID:3908); ovarian carcinoma (Disease Ontology:DOID:4001); pulmonary hypertension (Disease Ontology:DOID:6432); colorectal cancer (Disease Ontology:DOID:9256); type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": " (sce:YGL194C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "11711434;12434058;14562106;24374639;33491328;8962081;9046087;9169869", "class_list": "", "function": "Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). It is apparently involved in transcriptional activation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 14, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTW0", "ec_number_list": "3.5.1.98", "go_molecular_function": "GO:0004407 histone deacetylase activity;GO:0141221 histone deacetylase activity, hydrolytic mechanism", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0034399 nuclear periphery;GO:0034967 Set3 complex;GO:0070210 Rpd3L-Expanded complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0006974 DNA damage response;GO:0045727 positive regulation of translation;GO:0009267 cellular response to starvation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P53096-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53124-1", "uniprot_id": "PCL10_YEAST", "mass": 48584.0, "length": 433, "protein_name": "PHO85 cyclin-10", "gene_name": "PCL10", "organism": "Yeast", "refseq_name": "Pcl10p", "refseq_ac": "NP_011381", "gene_names_uniprotkb": "PCL10; G2838", "gene_names_refseq": "PCL10", "protein_names_uniprotkb": "PHO85 cyclin-10", "protein_names_refseq": "Pcl10p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL134W)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10490639;12407105;14562095;14562106;20489023;24374639;32597660;33481703;33491328;8840506;9032248;9169869;9584169", "class_list": "", "function": "Cyclin partner of the cyclin-dependent kinase (CDK) PHO85. Together with cyclin PCL8, negatively controls glycogen accumulation under favorable growth conditions. The PCL10-PHO85 cyclin-CDK holoenzyme has glycogen synthase kinase activity and phosphorylates and negatively regulates glycogen synthase GSY2. Also has minor GLC8 kinase activity., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VU15", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding;GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000307 cyclin-dependent protein kinase holoenzyme complex", "go_biological_process": "GO:0005977 glycogen metabolic process;GO:0005979 regulation of glycogen biosynthetic process;GO:0045719 negative regulation of glycogen biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P53124-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53135-1", "uniprot_id": "SLD3_YEAST", "mass": 77298.0, "length": 668, "protein_name": "DNA replication regulator SLD3", "gene_name": "SLD3", "organism": "Yeast", "refseq_name": "Sld3p", "refseq_ac": "NP_011402", "gene_names_uniprotkb": "SLD3; G2980", "gene_names_refseq": "SLD3", "protein_names_uniprotkb": "DNA replication regulator SLD3", "protein_names_refseq": "Sld3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL113W)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "11296242;12730134;14562106;17167415;17167417;17287358;19779198;20835227;20865002;21487389;21946560;23749301;24374639;30595439;32597660;33229814;33481703;33491328;9046090;9169869", "class_list": "", "function": "Required for loading and maintenance of stable association of CDC45 with chromatin during initiation and elongation of DNA replication. Also involved in temporal regulation of origin firing. Required for the association of PSF1 with origins., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 69, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VU34", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding", "go_cellular_component": "GO:0031261 DNA replication preinitiation complex;GO:0005634 nucleus;GO:0000775 chromosome, centromeric region;GO:0000785 chromatin", "go_biological_process": "GO:0006260 DNA replication;GO:0006270 DNA replication initiation;GO:0000727 double-strand break repair via break-induced replication;GO:0033314 mitotic DNA replication checkpoint signaling;GO:1903466 regulation of mitotic DNA replication initiation", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "P53135-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53224-1", "uniprot_id": "ORM1_YEAST", "mass": 25245.0, "length": 222, "protein_name": "Protein ORM1", "gene_name": "ORM1", "organism": "Yeast", "refseq_name": "sphingolipid homeostasis protein ORM1", "refseq_ac": "NP_011552", "gene_names_uniprotkb": "ORM1", "gene_names_refseq": "ORM1", "protein_names_uniprotkb": "Protein ORM1", "protein_names_refseq": "sphingolipid homeostasis protein ORM1", "tax_id": 559292, "disease": "childhood-onset asthma (Disease Ontology:DOID:0080815); asthma (Disease Ontology:DOID:2841); allergic asthma (Disease Ontology:DOID:9415)", "pathway": " (sce:YGR038W); (R-SCE-6798695)", "pathway_count": 2, "publication_count": 25, "publication_id_list": "14562095;14562106;16847258;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20182505;20702584;22080611;22814378;23749301;24374639;32597660;33481703;33491328;34492164;34965436;39490931;9169869;9290212;9434347", "class_list": "", "function": "Component of the SPOTS complex that acts as a negative regulator of sphingolipid synthesis (PubMed:20182505, PubMed:34492164, PubMed:39490931). Acts by inhibiting serine palmitoyltransferases (LCB1 and LCB2) activity (PubMed:20182505). Along with ORM2, plays a role in the phosphorylation of LAC1 and YPK1, the distribution of actin patches between mother and daughter cells, and in endocytosis (PubMed:39490931). Disruption or inhibition of sphingolipid synthesis leads to the activation and phosphorylation of YPK1 through the TORC2 and PKH1 pathways, which in turn phosphorylates ORM1 and LAG1 to activate sphingolipid synthesis (PubMed:34492164)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUH5", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0017059 serine palmitoyltransferase complex;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006897 endocytosis;GO:0030148 sphingolipid biosynthetic process;GO:0006672 ceramide metabolic process;GO:0090155 negative regulation of sphingolipid biosynthetic process;GO:0006986 response to unfolded protein", "synthesized_glycan_count": 0, "hit_score": 2.6, "record_id": "P53224-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53250-1", "uniprot_id": "TWF1_YEAST", "mass": 37071.0, "length": 332, "protein_name": "Twinfilin-1", "gene_name": "TWF1", "organism": "Yeast", "refseq_name": "twinfilin TWF1", "refseq_ac": "NP_011594", "gene_names_uniprotkb": "TWF1", "gene_names_refseq": "TWF1", "protein_names_uniprotkb": "Twinfilin-1; Twinfilin-A", "protein_names_refseq": "twinfilin TWF1", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR080W)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "14562106;18407956;19779198;20489023;21126336;21177495;23749301;24374639;30516470;32597660;33481703;33491328;9169869;9700161", "class_list": "", "function": "Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. Prevents actin filament assembly by forming a 1:1 complex with actin monomers, and inhibits the nucleotide exchange reaction of actin monomers (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUL2", "ec_number_list": "", "go_molecular_function": "GO:0003785 actin monomer binding;GO:0051015 actin filament binding;GO:0140311 protein sequestering activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005884 actin filament;GO:0043332 mating projection tip", "go_biological_process": "GO:0007015 actin filament organization;GO:0051016 barbed-end actin filament capping;GO:0051014 actin filament severing;GO:0030042 actin filament depolymerization;GO:0030836 positive regulation of actin filament depolymerization", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P53250-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53254-1", "uniprot_id": "UTP22_YEAST", "mass": 140485.0, "length": 1237, "protein_name": "U3 small nucleolar RNA-associated protein 22", "gene_name": "UTP22", "organism": "Yeast", "refseq_name": "rRNA-processing protein UTP22", "refseq_ac": "NP_011604", "gene_names_uniprotkb": "UTP22", "gene_names_refseq": "UTP22", "protein_names_uniprotkb": "U3 small nucleolar RNA-associated protein 22; U three protein 22; U3 snoRNA-associated protein 22", "protein_names_refseq": "rRNA-processing protein UTP22", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR090W); (R-SCE-6791226)", "pathway_count": 2, "publication_count": 23, "publication_id_list": "14562095;14562106;15590835;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22902402;23749301;24374639;26149687;30516470;32597660;33481703;33491328;9169869", "class_list": "", "function": "Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 18, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUM2", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0030686 90S preribosome;GO:0032040 small-subunit processome", "go_biological_process": "GO:0006409 tRNA export from nucleus;GO:0006364 rRNA processing;GO:0030490 maturation of SSU-rRNA;GO:0000028 ribosomal small subunit assembly;GO:0042790 nucleolar large rRNA transcription by RNA polymerase I", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P53254-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53280-1", "uniprot_id": "CF130_YEAST", "mass": 128780.0, "length": 1122, "protein_name": "Protein CAF130", "gene_name": "CAF130", "organism": "Yeast", "refseq_name": "CCR4-NOT core subunit CAF130", "refseq_ac": "NP_011650", "gene_names_uniprotkb": "CAF130", "gene_names_refseq": "CAF130", "protein_names_uniprotkb": "Protein CAF130; 130 kDa CCR4-associated factor", "protein_names_refseq": "CCR4-NOT core subunit CAF130", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR134W)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "11733989;14562106;17322287;18407956;19779198;19795423;19823750;22814378;23749301;24374639;32597660;33481703;33491328;9169869", "class_list": "", "function": "Acts as a component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUR6", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0030015 CCR4-NOT core complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0032968 positive regulation of transcription elongation by RNA polymerase II;GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P53280-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53286-1", "uniprot_id": "BTN2_YEAST", "mass": 47168.0, "length": 410, "protein_name": "Protein BTN2", "gene_name": "BTN2", "organism": "Yeast", "refseq_name": "Btn2p", "refseq_ac": "NP_011658", "gene_names_uniprotkb": "BTN2", "gene_names_refseq": "BTN2", "protein_names_uniprotkb": "Protein BTN2; Batten disease protein 2", "protein_names_refseq": "Btn2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YGR142W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "11053386;12456008;12615067;15701790;17563356;21441304;24374639;33481703;33491328;9169869", "class_list": "", "function": "V-SNARE binding protein that facilitates specific protein retrieval from a late endosome to the Golgi. Modulates the rate of arginine uptake. Involved in pH homeostasis. Required for the correct localization of IST2. May be involved in ion homeostasis together with IST2., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VUS2", "ec_number_list": "", "go_molecular_function": "GO:0051087 protein-folding chaperone binding;GO:0000149 SNARE binding;GO:0140311 protein sequestering activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm;GO:0005770 late endosome;GO:0034399 nuclear periphery", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006457 protein folding;GO:0006865 amino acid transport;GO:0034504 protein localization to nucleus;GO:0042147 retrograde transport, endosome to Golgi", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P53286-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53335-1", "uniprot_id": "PXR1_YEAST", "mass": 31312.0, "length": 271, "protein_name": "Protein PXR1", "gene_name": "PXR1", "organism": "Yeast", "refseq_name": "telomerase inhibitor", "refseq_ac": "NP_011796", "gene_names_uniprotkb": "PXR1; GNO1", "gene_names_refseq": "GNO1; PXR1", "protein_names_uniprotkb": "Protein PXR1; G-patch nucleolar protein; PinX1-related protein 1", "protein_names_refseq": "telomerase inhibitor", "tax_id": 559292, "disease": "cancer (Disease Ontology:DOID:162); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (sce:YGR280C)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "11701125;12107183;14562095;14562106;14977919;16544271;17322287;18407956;19779198;19795423;19823750;20489023;20702584;21126336;22218487;23749301;24374639;30516470;33481703;33491328;9090054;9169869", "class_list": "", "function": "Involved in rRNA-processing at A0, A1 and A2 sites through its action in U18 and U24 snoRNA 3'-end final trimming. Negative regulator of telomerase through competition for binding to EST2 with TLC1., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VV57;Q8TG89", "ec_number_list": "", "go_molecular_function": "GO:0008047 enzyme activator activity;GO:0003676 nucleic acid binding;GO:0010521 telomerase inhibitor activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus", "go_biological_process": "GO:0032211 negative regulation of telomere maintenance via telomerase;GO:0006364 rRNA processing;GO:0000494 box C/D sno(s)RNA 3'-end processing", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "P53335-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53550-1", "uniprot_id": "DCP2_YEAST", "mass": 108667.0, "length": 970, "protein_name": "m7GpppN-mRNA hydrolase", "gene_name": "DCP2", "organism": "Yeast", "refseq_name": "decapping enzyme complex catalytic subunit", "refseq_ac": "NP_014281", "gene_names_uniprotkb": "DCP2; N1917; PSU1", "gene_names_refseq": "DCP2; PSU1", "protein_names_uniprotkb": "m7GpppN-mRNA hydrolase; 3.6.1.62; Protein PSU1; mRNA-decapping enzyme subunit 2", "protein_names_refseq": "decapping enzyme complex catalytic subunit", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL118C); (R-SCE-430039); (R-SCE-450385); (R-SCE-450513)", "pathway_count": 4, "publication_count": 35, "publication_id_list": "10508173;10900456;11139489;11741542;12554866;12730603;14562106;14758354;15665377;17330950;17563356;18280238;18407956;18678652;18780730;19684113;19779198;19795423;19823750;20513766;20702584;21126336;21177495;22218487;23749301;24374639;24909858;26098573;30516470;32597660;33481703;33491328;7883168;9090055;9169873", "class_list": "", "function": "Catalytic component of the decapping complex necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay (PubMed:10508173, PubMed:11139489, PubMed:11741542). Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP (PubMed:12554866). Decapping is the major pathway of mRNA degradation in yeast and occurs through deadenylation, decapping and subsequent 5' to 3' exonucleolytic decay of the transcript body (PubMed:10508173, PubMed:11139489, PubMed:11741542). Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degradation of their transcripts (PubMed:19779198)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 64, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "B0KZS6;B0KZU4;B0KZW2;B0KZY0;B0KZY9;B0KZZ8;B0L007;D6W164;Q6LCS6", "ec_number_list": "3.1.13.-;3.6.4.13;3.6.1.62;3.1.26.-", "go_molecular_function": "GO:0003682 chromatin binding;GO:0003729 mRNA binding;GO:0016787 hydrolase activity;GO:0030145 manganese ion binding;GO:0140933 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000932 P-body;GO:0098562 cytoplasmic side of membrane;GO:0098745 RNA decapping complex", "go_biological_process": "GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0006397 mRNA processing;GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0034063 stress granule assembly", "synthesized_glycan_count": 0, "hit_score": 3.6, "record_id": "P53550-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53738-1", "uniprot_id": "TR112_YEAST", "mass": 15066.0, "length": 135, "protein_name": "Multifunctional methyltransferase subunit TRM112", "gene_name": "TRM112", "organism": "Yeast", "refseq_name": "RNA methylation protein TRM112", "refseq_ac": "NP_014444", "gene_names_uniprotkb": "TRM112; N3445", "gene_names_refseq": "TRM112", "protein_names_uniprotkb": "Multifunctional methyltransferase subunit TRM112; eRF1 MTase subunit TRM112; eRF1 methyltransferase subunit TRM112; tRNA methyltransferase 112", "protein_names_refseq": "RNA methylation protein TRM112", "tax_id": 559292, "disease": "", "pathway": " (sce:YNR046W); (R-SCE-156581); (R-SCE-72764)", "pathway_count": 3, "publication_count": 8, "publication_id_list": "14562095;14562106;15899842;17008308;22493060;22956767;24374639;9169873", "class_list": "", "function": "Acts as an activator of both rRNA/tRNA and protein methyltransferases. Together with methyltransferase MTQ2, required for the methylation of eRF1 on 'Gln-182'. Together with methyltransferase TRM11, required for the formation of 2-methylguanosine at position 10 (m2G10) in tRNA. Together with methyltransferase BUD23, required for the formation of 7-methylguanine at position 1575 (m7G1575) in 18S rRNA. Involved in biogenesis of both 40S and 60S ribosomal subunits., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1M1", "ec_number_list": "", "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0141106 tRNA methyltransferase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005840 ribosome", "go_biological_process": "GO:0070476 rRNA (guanine-N7)-methylation;GO:2000234 positive regulation of rRNA processing;GO:0042273 ribosomal large subunit biogenesis;GO:0002098 tRNA wobble uridine modification;GO:0030488 tRNA methylation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P53738-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53741-1", "uniprot_id": "BRE5_YEAST", "mass": 57674.0, "length": 515, "protein_name": "UBP3-associated protein BRE5", "gene_name": "BRE5", "organism": "Yeast", "refseq_name": "Bre5p", "refseq_ac": "NP_014449", "gene_names_uniprotkb": "BRE5; N3465", "gene_names_refseq": "BRE5", "protein_names_uniprotkb": "UBP3-associated protein BRE5; Brefeldin-A sensitivity protein 5", "protein_names_refseq": "Bre5p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNR051C)", "pathway_count": 1, "publication_count": 27, "publication_id_list": "11875433;12778054;14562106;17287358;17322287;17330950;17563356;17632125;18407956;19684113;19779198;19795423;19823750;20508643;20702584;21126336;21177495;23749301;24374639;24909858;27821475;30516470;32597660;33229814;33481703;33491328;9169873", "class_list": "", "function": "Has a role in de-ubiquitination. In conjunction with UBP3, cleaves ubiquitin, leading to the subsequent mono-ubiquitination of sec23., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 7, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 7, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 7, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 16, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "D6W1M6", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0000932 P-body;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:1901525 negative regulation of mitophagy;GO:0060628 regulation of ER to Golgi vesicle-mediated transport;GO:0045053 protein retention in Golgi apparatus;GO:0016579 protein deubiquitination;GO:0034063 stress granule assembly", "synthesized_glycan_count": 0, "hit_score": 3.6, "record_id": "P53741-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53743-1", "uniprot_id": "ESF2_YEAST", "mass": 36408.0, "length": 316, "protein_name": "Pre-rRNA-processing protein ESF2", "gene_name": "ESF2", "organism": "Yeast", "refseq_name": "RNA-binding ATPase activator ESF2", "refseq_ac": "NP_014452", "gene_names_uniprotkb": "ESF2; ABT1; N3491", "gene_names_refseq": "ABT1; ESF2", "protein_names_uniprotkb": "Pre-rRNA-processing protein ESF2; 18S rRNA factor 2", "protein_names_refseq": "RNA-binding ATPase activator ESF2", "tax_id": 559292, "disease": "", "pathway": " (sce:YNR054C)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "14562095;14562106;15964808;16772403;17330950;17563356;18407956;19779198;19795423;19823750;20702584;21126336;21177495;22218487;23749301;24374639;33481703;33491328;9169873", "class_list": "", "function": "Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2. Stimulates DBP8 RNA helicase ATPase activity., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1M9", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0001671 ATPase activator activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm", "go_biological_process": "GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0034462 small-subunit processome assembly", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P53743-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53756-1", "uniprot_id": "PDR18_YEAST", "mass": 149750.0, "length": 1333, "protein_name": "ABC transporter ATP-binding protein/permease PDR18", "gene_name": "PDR18", "organism": "Yeast", "refseq_name": "ATP-binding cassette multidrug transporter PDR18", "refseq_ac": "NP_014468", "gene_names_uniprotkb": "PDR18; N3568", "gene_names_refseq": "PDR18", "protein_names_uniprotkb": "ABC transporter ATP-binding protein/permease PDR18; Pleiotropic drug resistance protein 18", "protein_names_refseq": "ATP-binding cassette multidrug transporter PDR18", "tax_id": 559292, "disease": "", "pathway": " (sce:YNR070W)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "24374639;33481703;9169873", "class_list": "", "function": "", "predicted_glycosites": 8, "predicted_n_glycosites": 8, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "D6W1P5", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0008559 ABC-type xenobiotic transporter activity;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0071466 cellular response to xenobiotic stimulus;GO:0009410 response to xenobiotic stimulus;GO:0055092 sterol homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P53756-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53840-1", "uniprot_id": "TOF1_YEAST", "mass": 141120.0, "length": 1238, "protein_name": "Topoisomerase 1-associated factor 1", "gene_name": "TOF1", "organism": "Yeast", "refseq_name": "Tof1p", "refseq_ac": "NP_014126", "gene_names_uniprotkb": "TOF1; N0636", "gene_names_refseq": "TOF1", "protein_names_uniprotkb": "Topoisomerase 1-associated factor 1", "protein_names_refseq": "Tof1p", "tax_id": 559292, "disease": "advanced sleep phase syndrome (Disease Ontology:DOID:0050628); advanced sleep phase syndrome 4 (Disease Ontology:DOID:0061006); alcohol use disorder (Disease Ontology:DOID:1574)", "pathway": " (sce:YNL273W)", "pathway_count": 1, "publication_count": 29, "publication_id_list": "10028183;11156979;12944972;14562095;14562106;14742714;15598824;15755447;16024805;16137625;16219777;16418273;16569515;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;23749301;24374639;27017623;32597660;33481703;33491328;9169873", "class_list": "", "function": "Forms a fork protection complex (FPC) with CSM3 and which is required for chromosome segregation during meiosis and DNA damage repair. FPC coordinates leading and lagging strand synthesis and moves with the replication fork. FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors and protects stalled replication forks against the fork-releasing activity of RRM3 helicase., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 21, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0S1", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0031298 replication fork protection complex;GO:0043596 nuclear replication fork;GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0000076 DNA replication checkpoint signaling;GO:0006281 DNA repair;GO:0006260 DNA replication;GO:0043570 maintenance of DNA repeat elements;GO:0051321 meiotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 3.0, "record_id": "P53840-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53859-1", "uniprot_id": "CSL4_YEAST", "mass": 31583.0, "length": 292, "protein_name": "Exosome complex component CSL4", "gene_name": "CSL4", "organism": "Yeast", "refseq_name": "exosome non-catalytic core subunit CSL4", "refseq_ac": "NP_014167", "gene_names_uniprotkb": "CSL4; N1154; SKI4", "gene_names_refseq": "CSL4; SKI4", "protein_names_uniprotkb": "Exosome complex component CSL4; CEP1 synthetic lethal protein 4", "protein_names_refseq": "exosome non-catalytic core subunit CSL4", "tax_id": 559292, "disease": "pontocerebellar hypoplasia type 1F (Disease Ontology:DOID:0112331); microcephaly (Disease Ontology:DOID:10907); scleral disease (Disease Ontology:DOID:11343); dilated cardiomyopathy (Disease Ontology:DOID:12930)", "pathway": " (sce:YNL232W); (R-SCE-429958); (R-SCE-450385); (R-SCE-450513); (R-SCE-6791226)", "pathway_count": 5, "publication_count": 23, "publication_id_list": "10465791;14562095;14562106;16829593;17173052;17174896;17287358;18407956;19046973;19060898;19795423;19823750;20702584;21126336;22218487;24374639;30181345;32597660;33481703;33491328;8896273;9169873;9584087", "class_list": "", "function": "Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and in RNA surveillance pathways, preventing translation of aberrant mRNAs. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0W0", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0000176 nuclear exosome (RNase complex);GO:0000177 cytoplasmic exosome (RNase complex)", "go_biological_process": "GO:0070481 nuclear-transcribed mRNA catabolic process, non-stop decay;GO:0006396 RNA processing;GO:0006397 mRNA processing;GO:0000956 nuclear-transcribed mRNA catabolic process;GO:0006401 RNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P53859-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53866-1", "uniprot_id": "SQS1_YEAST", "mass": 86950.0, "length": 767, "protein_name": "Protein SQS1", "gene_name": "SQS1", "organism": "Yeast", "refseq_name": "Sqs1p", "refseq_ac": "NP_014175", "gene_names_uniprotkb": "SQS1; N1269", "gene_names_refseq": "PFA1; SQS1", "protein_names_uniprotkb": "Protein SQS1; Squelch of splicing suppression protein 1", "protein_names_refseq": "Sqs1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL224C)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "14562095;14562106;16945917;17330950;17563356;18407956;19684113;19779198;20702584;21126336;21177495;23749301;24374639;24909858;30516470;32597660;33481703;33491328;8896273;9169873", "class_list": "", "function": "May be involved in splicing since overexpression antagonizes the suppression of splicing defects by SPP382 mutants., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 21, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W0W6", "ec_number_list": "", "go_molecular_function": "GO:0008047 enzyme activator activity;GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0030687 preribosome, large subunit precursor;GO:0030688 preribosome, small subunit precursor", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0006364 rRNA processing;GO:0030490 maturation of SSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P53866-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53894-1", "uniprot_id": "CBK1_YEAST", "mass": 86946.0, "length": 756, "protein_name": "Serine/threonine-protein kinase CBK1", "gene_name": "CBK1", "organism": "Yeast", "refseq_name": "serine/threonine protein kinase CBK1", "refseq_ac": "NP_014238", "gene_names_uniprotkb": "CBK1; N1727", "gene_names_refseq": "CBK1", "protein_names_uniprotkb": "Serine/threonine-protein kinase CBK1; 2.7.11.1; Cell wall biosynthesis kinase", "protein_names_refseq": "serine/threonine protein kinase CBK1", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL161W)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "11854408;12196508;14562106;17145962;17563356;18407956;19684113;19779198;19967545;20702584;21135117;21177495;22218487;23749301;24374639;32597660;33481703;33491328;8686380;9169873", "class_list": "", "function": "Protein kinase that seems to play a role in the regulation of cell morphogenesis and proliferation., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 26, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W122", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005938 cell cortex;GO:0010494 cytoplasmic stress granule;GO:0000131 incipient cellular bud site", "go_biological_process": "GO:0000920 septum digestion after cytokinesis;GO:0035556 intracellular signal transduction;GO:0050708 regulation of protein secretion;GO:0030950 establishment or maintenance of actin cytoskeleton polarity;GO:0007163 establishment or maintenance of cell polarity", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P53894-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53905-1", "uniprot_id": "LSM7_YEAST", "mass": 13006.0, "length": 115, "protein_name": "LSM complex subunit LSM7", "gene_name": "LSM7", "organism": "Yeast", "refseq_name": "Sm-like protein LSM7", "refseq_ac": "NP_014252", "gene_names_uniprotkb": "LSM7; N1202; N1780", "gene_names_refseq": "LSM7", "protein_names_uniprotkb": "LSM complex subunit LSM7", "protein_names_refseq": "Sm-like protein LSM7", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL147W); (R-SCE-430039)", "pathway_count": 2, "publication_count": 23, "publication_id_list": "10369684;10428970;10449419;10747033;10761922;12077351;12438310;14562095;14562106;14627812;15075370;15485930;17101987;22814378;24139796;24240276;24374639;24513854;29717126;30059503;8619318;8686380;9169873", "class_list": "", "function": "Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner (PubMed:10747033, PubMed:12077351, PubMed:12438310, PubMed:14627812, PubMed:24513854). Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation by activating the decapping step (PubMed:10747033, PubMed:10761922, PubMed:24513854). Together with PAT1, the LSM1-LSM7 complex binds to osmotic stress-activated mRNAs to attenuate the osmotic stress response, probably by limiting ribosome access to the mRNA and consequently translation (PubMed:30059503). Component of the nuclear LSM2-LSM8 complex, which is involved in spliceosome assembly (PubMed:10747033, PubMed:12077351, PubMed:12438310, PubMed:14627812). The LSM2-LSM8 complex plays a role in the biogenesis of the spliceosomal U4/U6-U5 tri-snRNP complex by accelerating PRP24-mediated annealing of U4/U6 di-snRNA (PubMed:10747033, PubMed:24240276, PubMed:29717126). The LSM2-LSM8 complex binds U6 snRNA terminating with a non-cyclic 3' phosphate group (PubMed:29717126). LSM2-LSM8 is probably also involved in degradation of nuclear pre-mRNA by targeting them for decapping (PubMed:15485930). LSM2-LSM8 could be involved in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA, although involvement may be indirect (PubMed:12077351, PubMed:12438310, PubMed:15075370). In a complex that probably contains LSM2-LSM7, but not LSM1 or LSM8, associates with the precursor of the RNA component of RNase P (pre-P RNA) and may be involved in maturing pre-P RNA; the complex also associates with snoRNA SNR5 (PubMed:10369684, PubMed:15075370)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W135", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0000932 P-body;GO:0071013 catalytic step 2 spliceosome", "go_biological_process": "GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0008033 tRNA processing;GO:0000956 nuclear-transcribed mRNA catabolic process;GO:0000398 mRNA splicing, via spliceosome;GO:0006364 rRNA processing", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P53905-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53933-1", "uniprot_id": "APP1_YEAST", "mass": 66134.0, "length": 587, "protein_name": "Phosphatidate phosphatase APP1", "gene_name": "APP1", "organism": "Yeast", "refseq_name": "phosphatidate phosphatase APP1", "refseq_ac": "NP_014305", "gene_names_uniprotkb": "APP1; N2219", "gene_names_refseq": "APP1", "protein_names_uniprotkb": "Phosphatidate phosphatase APP1; 3.1.3.4; Actin patch protein 1; PAP", "protein_names_refseq": "phosphatidate phosphatase APP1", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL094W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "11489916;14562095;14562106;14737190;19756047;23071111;23335564;24374639;8771715;9169873", "class_list": "", "function": "Mg(2+)-dependent phosphatidate (PA) phosphatase which catalyzes the dephosphorylation of PA to yield diacylglycerol. May play a role in vesicular trafficking through its PAP activity at cortical actin patches (PubMed:23071111, PubMed:23335564). Can also utilize diacylglycerol pyrophosphate and lyso-PA as substrates with specificity constants 4- and 7-fold lower, respectively, when compared with PA (PubMed:23335564)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W186", "ec_number_list": "3.1.3.4;3.1.3.106;3.6.1.75", "go_molecular_function": "GO:0008195 phosphatidate phosphatase activity", "go_cellular_component": "GO:0030479 actin cortical patch", "go_biological_process": "GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P53933-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53939-1", "uniprot_id": "NIS1_YEAST", "mass": 45908.0, "length": 407, "protein_name": "Protein NIS1", "gene_name": "NIS1", "organism": "Yeast", "refseq_name": "Nis1p", "refseq_ac": "NP_014321", "gene_names_uniprotkb": "NIS1; JIP1; N2337", "gene_names_refseq": "JIP1; NIS1", "protein_names_uniprotkb": "Protein NIS1; Jumonji domain-interacting protein 1; Neck protein interacting with septins protein 1", "protein_names_refseq": "Nis1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL078W)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "11309124;11817649;12101299;14562095;14562106;15107529;15665377;16923829;17043893;17330950;17728242;18086883;18407956;19779198;19795423;19823750;23749301;24374639;32597660;33481703;33491328;8701611;9169873", "class_list": "", "function": "May be involved in a mitotic signaling network. Binds sumoylated proteins and may stabilize SUMO chains., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1A1", "ec_number_list": "", "go_molecular_function": "GO:0032183 SUMO binding", "go_cellular_component": "GO:0005634 nucleus;GO:0032153 cell division site;GO:0005621 cellular bud scar;GO:0005935 cellular bud neck;GO:0032174 cellular bud neck septin collar", "go_biological_process": "GO:0045184 establishment of protein localization;GO:0140014 mitotic nuclear division;GO:0007120 axial cellular bud site selection", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "P53939-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53953-1", "uniprot_id": "SFB2_YEAST", "mass": 98944.0, "length": 876, "protein_name": "SED5-binding protein 2", "gene_name": "SFB2", "organism": "Yeast", "refseq_name": "COPII subunit SFB2", "refseq_ac": "NP_014349", "gene_names_uniprotkb": "SFB2; ISS1; N2505; YNL2505C", "gene_names_refseq": "ISS1; SFB2", "protein_names_uniprotkb": "SED5-binding protein 2; SEC24-related protein 2", "protein_names_refseq": "COPII subunit SFB2", "tax_id": 559292, "disease": "", "pathway": " (sce:YNL049C)", "pathway_count": 1, "publication_count": 21, "publication_id_list": "10712514;10749860;10753972;14562106;15665377;16269340;17261844;17322287;17330950;18407956;19779198;20702584;21126336;23749301;24374639;32597660;33481703;33491328;8533472;8740423;9169873", "class_list": "", "function": "Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1D0", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0005048 signal sequence binding;GO:0000149 SNARE binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005789 endoplasmic reticulum membrane;GO:0070971 endoplasmic reticulum exit site;GO:0030127 COPII vesicle coat", "go_biological_process": "GO:0090110 COPII-coated vesicle cargo loading;GO:0006886 intracellular protein transport", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P53953-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53954-1", "uniprot_id": "ALG11_YEAST", "mass": 63143.0, "length": 548, "protein_name": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase", "gene_name": "ALG11", "organism": "Yeast", "refseq_name": "alpha-1,2-mannosyltransferase ALG11", "refseq_ac": "NP_014350", "gene_names_uniprotkb": "ALG11; N2510; YNL2510W", "gene_names_refseq": "ALG11", "protein_names_uniprotkb": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase; 2.4.1.131; Alpha-1,2-mannosyltransferase ALG11; Asparagine-linked glycosylation protein 11; Glycolipid 2-alpha-mannosyltransferase", "protein_names_refseq": "alpha-1,2-mannosyltransferase ALG11", "tax_id": 559292, "disease": "congenital disorder of glycosylation Ip (Disease Ontology:DOID:0080567)", "pathway": " (sce:YNL048W)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "11278778;11308030;14562106;15044395;16878994;19929855;24374639;8533472;8740423;9169873", "class_list": "", "function": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes, on the cytoplasmic face of the endoplasmic reticulum, the addition of the fourth and fifth mannose residues to the dolichol-linked oligosaccharide chain, to produce Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide (PubMed:11278778, PubMed:16878994, PubMed:19929855). Man(5)GlcNAc(2)-PP-dolichol is a substrate for ALG3, the following enzyme in the biosynthetic pathway (PubMed:11308030)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 11, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1D1", "ec_number_list": "2.4.1.131", "go_molecular_function": "GO:0004377 GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity;GO:0000026 alpha-1,2-mannosyltransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0009101 glycoprotein biosynthetic process;GO:0006488 dolichol-linked oligosaccharide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P53954-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53969-1", "uniprot_id": "SAM50_YEAST", "mass": 54406.0, "length": 484, "protein_name": "Sorting assembly machinery 50 kDa subunit", "gene_name": "SAM50", "organism": "Yeast", "refseq_name": "SAM complex subunit SAM50", "refseq_ac": "NP_014372", "gene_names_uniprotkb": "SAM50; N2802; TOB55", "gene_names_refseq": "OMP85; SAM50; TOB55", "protein_names_uniprotkb": "Sorting assembly machinery 50 kDa subunit; TOB complex 55 kDa subunit", "protein_names_refseq": "SAM complex subunit SAM50", "tax_id": 559292, "disease": "metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208)", "pathway": " (sce:YNL026W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14570913;14685243;15590639;24374639;33491328;9169873", "class_list": "", "function": "Component of the mitochondrial outer membrane sorting assembly machinery (SAM or TOB) complex, which is required for the sorting of proteins with complicated topology, such as beta-barrel proteins, to the mitochondrial outer membrane after import by the TOM complex., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1F2", "ec_number_list": "", "go_molecular_function": "GO:0032977 membrane insertase activity;GO:0008320 protein transmembrane transporter activity", "go_cellular_component": "GO:0001401 SAM complex;GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0045040 protein insertion into mitochondrial outer membrane;GO:0030150 protein import into mitochondrial matrix;GO:0065003 protein-containing complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P53969-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53974-1", "uniprot_id": "ARK1_YEAST", "mass": 71373.0, "length": 638, "protein_name": "Actin-regulating kinase 1", "gene_name": "ARK1", "organism": "Yeast", "refseq_name": "serine/threonine protein kinase ARK1", "refseq_ac": "NP_014378", "gene_names_uniprotkb": "ARK1; N2823", "gene_names_refseq": "ARK1", "protein_names_uniprotkb": "Actin-regulating kinase 1; 2.7.11.1", "protein_names_refseq": "serine/threonine protein kinase ARK1", "tax_id": 559292, "disease": "Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (sce:YNL020C)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "10087264;11668184;11694597;14562095;14562106;17287358;17563356;18407956;19779198;20489023;21126336;23749301;24374639;24909858;32597660;33229814;33481703;33491328;9169873", "class_list": "", "function": "Involved in regulation of actin cytoskeleton organization and endocytosis., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 13, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 13, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 13, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 17, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 13, "binding_glycan_count": 0, "secondary_ac_list": "D6W1F9", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0030479 actin cortical patch;GO:0043332 mating projection tip", "go_biological_process": "GO:0007015 actin filament organization;GO:2000369 regulation of clathrin-dependent endocytosis;GO:0000147 actin cortical patch assembly", "synthesized_glycan_count": 0, "hit_score": 3.4, "record_id": "P53974-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P54000-1", "uniprot_id": "SUB1_YEAST", "mass": 33102.0, "length": 292, "protein_name": "RNA polymerase II transcriptional coactivator SUB1", "gene_name": "SUB1", "organism": "Yeast", "refseq_name": "chromatin-binding transcription coactivator SUB1", "refseq_ac": "NP_013753", "gene_names_uniprotkb": "SUB1; TSP1; YM9532.04C", "gene_names_refseq": "SUB1; TSP1", "protein_names_uniprotkb": "RNA polymerase II transcriptional coactivator SUB1", "protein_names_refseq": "chromatin-binding transcription coactivator SUB1", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR039C)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "14562106;17330950;17563356;18407956;19779198;19795423;19823750;20702584;21126336;21177495;22218487;23749301;24374639;30516470;32597660;33481703;33491328;8617240;9169872", "class_list": "", "function": "Plays a role in the release of TFIIB from the transcription complex during transcription initiation. Binds to TFIIB and specifically inhibits the formation of the TBP-TFIIB-promoter complexes., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZL4", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0051880 G-quadruplex DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006303 double-strand break repair via nonhomologous end joining;GO:0045945 positive regulation of transcription by RNA polymerase III", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P54000-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P54730-1", "uniprot_id": "UBX4_YEAST", "mass": 46965.0, "length": 416, "protein_name": "UBX domain-containing protein 4", "gene_name": "UBX4", "organism": "Yeast", "refseq_name": "Ubx4p", "refseq_ac": "NP_013783", "gene_names_uniprotkb": "UBX4; YM9916.06C", "gene_names_refseq": "CUI1; UBX4", "protein_names_uniprotkb": "UBX domain-containing protein 4", "protein_names_refseq": "Ubx4p", "tax_id": 559292, "disease": "alveolar soft part sarcoma (Disease Ontology:DOID:4239)", "pathway": " (sce:YMR067C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562095;14562106;15258615;18407956;23749301;24374639;33481703;33491328;9169872", "class_list": "", "function": "Involved in CDC48-dependent protein degradation through the ubiquitin/proteasome pathway., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZP1", "ec_number_list": "", "go_molecular_function": "GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0012506 vesicle membrane", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0036503 ERAD pathway;GO:0030435 sporulation resulting in formation of a cellular spore", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P54730-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P54784-1", "uniprot_id": "ORC1_YEAST", "mass": 104400.0, "length": 914, "protein_name": "Origin recognition complex subunit 1", "gene_name": "ORC1", "organism": "Yeast", "refseq_name": "origin recognition complex subunit 1", "refseq_ac": "NP_013646", "gene_names_uniprotkb": "ORC1", "gene_names_refseq": "ORC1", "protein_names_uniprotkb": "Origin recognition complex subunit 1; Origin recognition complex 120 kDa subunit", "protein_names_refseq": "origin recognition complex subunit 1", "tax_id": 559292, "disease": "Meier-Gorlin syndrome (Disease Ontology:DOID:0060306); Meier-Gorlin syndrome 1 (Disease Ontology:DOID:0080512)", "pathway": " (sce:YML065W); (R-SCE-176187); (R-SCE-68616); (R-SCE-68689); (R-SCE-68949); (R-SCE-68962)", "pathway_count": 6, "publication_count": 20, "publication_id_list": "11168584;14562106;17330950;17563356;17825064;18407956;19520826;19779198;20702584;21126336;21177495;22218487;23749301;24374639;32597660;33481703;33491328;7579692;7585959;9169872", "class_list": "", "function": "Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcriptional silencing. Binds to the ARS consensus sequence (ACS) of origins of replication., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZA8", "ec_number_list": "", "go_molecular_function": "GO:0003688 DNA replication origin binding;GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005656 nuclear pre-replicative complex;GO:0031261 DNA replication preinitiation complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005664 nuclear origin of replication recognition complex", "go_biological_process": "GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication;GO:0034728 nucleosome organization;GO:0006270 DNA replication initiation;GO:0033314 mitotic DNA replication checkpoint signaling;GO:0043007 maintenance of rDNA", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P54784-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P80967-1", "uniprot_id": "TOM5_YEAST", "mass": 5985.0, "length": 50, "protein_name": "Mitochondrial import receptor subunit TOM5", "gene_name": "TOM5", "organism": "Yeast", "refseq_name": "Tom5p", "refseq_ac": "NP_015459", "gene_names_uniprotkb": "TOM5; MOM8A", "gene_names_refseq": "MOM8A; TOM5", "protein_names_uniprotkb": "Mitochondrial import receptor subunit TOM5; Translocase of outer membrane 5 kDa subunit", "protein_names_refseq": "Tom5p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR133W-A)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "17322287;22814378;24374639;9169875;9217162;9774667", "class_list": "", "function": "Component of the TOM (translocase of outer membrane) receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. TOM5 is involved in insertion of preproteins into the TOM40 translocation pore., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W4D0", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0005742 mitochondrial outer membrane translocase complex", "go_biological_process": "GO:0045040 protein insertion into mitochondrial outer membrane;GO:0006626 protein targeting to mitochondrion;GO:0071806 protein transmembrane transport;GO:0070096 mitochondrial outer membrane translocase complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P80967-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q00245-1", "uniprot_id": "RHO3_YEAST", "mass": 25312.0, "length": 231, "protein_name": "GTP-binding protein RHO3", "gene_name": "RHO3", "organism": "Yeast", "refseq_name": "Rho family GTPase RHO3", "refseq_ac": "NP_012148", "gene_names_uniprotkb": "RHO3", "gene_names_refseq": "RHO3", "protein_names_uniprotkb": "GTP-binding protein RHO3; 3.6.5.2", "protein_names_refseq": "Rho family GTPase RHO3", "tax_id": 559292, "disease": "", "pathway": " (sce:YIL118W); (R-SCE-198203); (R-SCE-392451); (R-SCE-416482); (R-SCE-5625740); (R-SCE-6798695); (R-SCE-8980692); (R-SCE-9013106); (R-SCE-9035034); (R-SCE-9696264); (R-SCE-9696270); (R-SCE-9696273)", "pathway_count": 12, "publication_count": 11, "publication_id_list": "10526184;1448099;14562106;1587484;17322287;23749301;24374639;33002606;33491328;8852836;9169870", "class_list": "", "function": "Plays an important role in cell growth (PubMed:1448099). Required to keep the uninucleated state (PubMed:1448099). Modulates morphogenesis during bud growth via directing organization of the actin cytoskeleton and the position of the secretory machinery for exocytosis (PubMed:1448099, PubMed:8852836)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VVG9", "ec_number_list": "3.6.5.2;3.6.5.3;3.6.5.-;3.6.5.4;2.7.11.13;3.1.3.48;3.6.5.5;1.3.1.70;3.1.4.4;3.4.11.-;3.4.-.-;3.6.4.-;1.2.1.3;1.2.1.64;2.7.11.1", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0019901 protein kinase binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005933 cellular bud", "go_biological_process": "GO:0007015 actin filament organization;GO:0007165 signal transduction;GO:0032956 regulation of actin cytoskeleton organization;GO:0007264 small GTPase-mediated signal transduction;GO:0030950 establishment or maintenance of actin cytoskeleton polarity", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q00245-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q00618-1", "uniprot_id": "PGTA_YEAST", "mass": 39675.0, "length": 327, "protein_name": "Geranylgeranyl transferase type-2 subunit alpha", "gene_name": "BET4", "organism": "Yeast", "refseq_name": "Rab geranylgeranyltransferase BET4", "refseq_ac": "NP_012503", "gene_names_uniprotkb": "BET4; J1254", "gene_names_refseq": "BET4", "protein_names_uniprotkb": "Geranylgeranyl transferase type-2 subunit alpha; 2.5.1.60; GGTase-II-alpha; Geranylgeranyl transferase type II subunit alpha; PGGT; Type II protein geranyl-geranyltransferase subunit alpha; YPT1/SEC4 proteins geranylgeranyltransferase subunit alpha", "protein_names_refseq": "Rab geranylgeranyltransferase BET4", "tax_id": 559292, "disease": "Hermansky-Pudlak syndrome (Disease Ontology:DOID:3753)", "pathway": " (sce:YJL031C); (R-SCE-6803205); (R-SCE-8873719)", "pathway_count": 3, "publication_count": 7, "publication_id_list": "12844361;1651172;24374639;33491328;8232541;8232542;8641269", "class_list": "", "function": "Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to proteins having the C-terminal -XCC or -XCXC, where both cysteines may become modified. Acts on YPT1 and SEC4., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VWF1", "ec_number_list": "2.5.1.59;2.5.1.60;2.5.1.58", "go_molecular_function": "GO:0004663 Rab geranylgeranyltransferase activity;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005777 peroxisome;GO:0005829 cytosol;GO:0005968 Rab-protein geranylgeranyltransferase complex", "go_biological_process": "GO:0006612 protein targeting to membrane;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0018344 protein geranylgeranylation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q00618-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q01454-1", "uniprot_id": "CTF4_YEAST", "mass": 104425.0, "length": 927, "protein_name": "DNA polymerase alpha-binding protein", "gene_name": "CTF4", "organism": "Yeast", "refseq_name": "chromatin-binding protein CTF4", "refseq_ac": "NP_015461", "gene_names_uniprotkb": "CTF4; CHL15; P9659.7; POB1", "gene_names_refseq": "CHL15; CTF4; POB1", "protein_names_uniprotkb": "DNA polymerase alpha-binding protein; Chromosome replication protein CHL15; Chromosome transmission fidelity protein 4; Protein POB1", "protein_names_refseq": "chromatin-binding protein CTF4", "tax_id": 559292, "disease": "cholangiocarcinoma (Disease Ontology:DOID:4947)", "pathway": " (sce:YPR135W)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "1341195;1448101;14562106;17330950;17563356;18407956;19779198;19795423;19823750;20702584;21126336;23749301;24374639;27017623;33481703;33491328;8316240;9169875", "class_list": "", "function": "Accessory factor for DNA replication. It plays a role in accurately duplicating the genome in vivo., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W4D2", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0043596 nuclear replication fork;GO:0005634 nucleus;GO:0000228 nuclear chromosome", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0006281 DNA repair;GO:0006334 nucleosome assembly;GO:0006270 DNA replication initiation;GO:0000727 double-strand break repair via break-induced replication", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "Q01454-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q01477-1", "uniprot_id": "UBP3_YEAST", "mass": 101917.0, "length": 912, "protein_name": "Ubiquitin carboxyl-terminal hydrolase 3", "gene_name": "UBP3", "organism": "Yeast", "refseq_name": "mRNA-binding ubiquitin-specific protease UBP3", "refseq_ac": "NP_011078", "gene_names_uniprotkb": "UBP3", "gene_names_refseq": "BLM3; UBP3", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase 3; 3.4.19.12; Deubiquitinating enzyme 3; Ubiquitin thioesterase 3; Ubiquitin-specific-processing protease 3", "protein_names_refseq": "mRNA-binding ubiquitin-specific protease UBP3", "tax_id": 559292, "disease": "", "pathway": " (sce:YER151C)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "12778054;1429680;14562106;17632125;18407956;19779198;19795423;19823750;20508643;20702584;21126336;21177495;21743437;22031224;23749301;24374639;32597660;33229814;33481703;33491328;8752220;9169868", "class_list": "", "function": "Has an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety in natural or engineered linear fusion proteins, irrespective of their size or the presence of an N-terminal extension to ubiquitin (PubMed:12778054, PubMed:17632125). Plays a role in regulation of silencing by interacting with SIR4 (PubMed:8752220). Also, in conjunction with BRE5, cleaves ubiquitin, leading to the subsequent mono-ubiquitination of SEC23 (PubMed:12778054). Required for ribophagy, a process which relocalizes ribosomal particles into the vacuole for degradation in response to starvation (PubMed:20508643)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 15, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 15, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 15, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 35, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 15, "binding_glycan_count": 0, "secondary_ac_list": "D3DM58", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:1990861 Ubp3-Bre5 deubiquitination complex", "go_biological_process": "GO:1901525 negative regulation of mitophagy;GO:0060628 regulation of ER to Golgi vesicle-mediated transport;GO:0045053 protein retention in Golgi apparatus;GO:0006508 proteolysis;GO:0016579 protein deubiquitination", "synthesized_glycan_count": 0, "hit_score": 3.9, "record_id": "Q01477-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q02208-1", "uniprot_id": "TOF2_YEAST", "mass": 86366.0, "length": 771, "protein_name": "Topoisomerase 1-associated factor 2", "gene_name": "TOF2", "organism": "Yeast", "refseq_name": "Tof2p", "refseq_ac": "NP_012935", "gene_names_uniprotkb": "TOF2; YK109", "gene_names_refseq": "TOF2", "protein_names_uniprotkb": "Topoisomerase 1-associated factor 2", "protein_names_refseq": "Tof2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YKR010C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10028183;1441752;14562106;18407956;19779198;20489023;23749301;24374639;30516470;32597660;33481703;33491328;8196765", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 18, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VX76", "ec_number_list": "", "go_molecular_function": "GO:0000182 rDNA binding;GO:0019211 phosphatase activator activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0005739 mitochondrion", "go_biological_process": "GO:0007000 nucleolus organization;GO:0000183 rDNA heterochromatin formation;GO:0070550 rDNA chromatin condensation;GO:0034503 protein localization to nucleolar rDNA repeats", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q02208-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q02354-1", "uniprot_id": "UTP6_YEAST", "mass": 52418.0, "length": 440, "protein_name": "U3 small nucleolar RNA-associated protein 6", "gene_name": "UTP6", "organism": "Yeast", "refseq_name": "snoRNA-binding rRNA-processing protein UTP6", "refseq_ac": "NP_010737", "gene_names_uniprotkb": "UTP6; D9461.34", "gene_names_refseq": "UTP6", "protein_names_uniprotkb": "U3 small nucleolar RNA-associated protein 6; U three protein 6; U3 snoRNA-associated protein 6", "protein_names_refseq": "snoRNA-binding rRNA-processing protein UTP6", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR449C); (R-SCE-6791226)", "pathway_count": 2, "publication_count": 14, "publication_id_list": "12068309;12150911;14562106;14759368;15590835;1638630;17515605;19795423;19823750;24374639;33229814;33481703;33491328;9169867", "class_list": "", "function": "Component of the SSU processome, a pre-ribosomal particle required for the maturation of the 18S rRNA from the 35S pre-rRNA precursor., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VT74;Q04115", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0030515 snoRNA binding;GO:0034511 U3 snoRNA binding", "go_cellular_component": "GO:0034388 Pwp2p-containing subcomplex of 90S preribosome;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0030686 90S preribosome;GO:0032040 small-subunit processome", "go_biological_process": "GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0030490 maturation of SSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q02354-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q02685-1", "uniprot_id": "RMI1_YEAST", "mass": 26860.0, "length": 241, "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "organism": "Yeast", "refseq_name": "Rmi1p", "refseq_ac": "NP_015301", "gene_names_uniprotkb": "RMI1; NCE4", "gene_names_refseq": "NCE4; RMI1", "protein_names_uniprotkb": "RecQ-mediated genome instability protein 1", "protein_names_refseq": "Rmi1p", "tax_id": 559292, "disease": "primary ovarian insufficiency (Disease Ontology:DOID:5426)", "pathway": " (sce:YPL024W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "12482937;14562095;14562106;15889139;15899853;17563356;24374639;33491328;9169875", "class_list": "", "function": "Structure-specific DNA-binding protein with a preference for cruciform structures. Also binds single-stranded DNA (ssDNA). Functions together with SGS1 and TOP3 to maintain genome integrity. Essential for proper meiotic cell division. Required for normal S-phase progression and DNA damage response. Required for resistance to the DNA-damaging agent methyl methanesulfonate (MMS)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3Y8", "ec_number_list": "", "go_molecular_function": "GO:0008047 enzyme activator activity;GO:0003697 single-stranded DNA binding;GO:0000400 four-way junction DNA binding", "go_cellular_component": "GO:0043596 nuclear replication fork;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0031422 RecQ family helicase-topoisomerase III complex", "go_biological_process": "GO:0051301 cell division;GO:0006974 DNA damage response;GO:0000724 double-strand break repair via homologous recombination;GO:0006265 DNA topological change;GO:0051321 meiotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q02685-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q02767-1", "uniprot_id": "VPS28_YEAST", "mass": 27702.0, "length": 242, "protein_name": "Vacuolar protein sorting-associated protein 28", "gene_name": "VPS28", "organism": "Yeast", "refseq_name": "ESCRT-I subunit protein VPS28", "refseq_ac": "NP_015260", "gene_names_uniprotkb": "VPS28; LPE5W; VPT28", "gene_names_refseq": "VPL13; VPS28; VPT28", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 28; ESCRT-I complex subunit VPS28", "protein_names_refseq": "ESCRT-I subunit protein VPS28", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL065W)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "12900393;14562095;14562106;16615893;16615894;16749904;17215868;17322287;17442384;24374639;33491328;8817003;9169875", "class_list": "", "function": "Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for normal endocytic and biosynthetic traffic to the yeast vacuole., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3V0;E9P8X2;P87328", "ec_number_list": "", "go_molecular_function": "GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0005768 endosome;GO:0005829 cytosol;GO:0031902 late endosome membrane;GO:0000813 ESCRT I complex", "go_biological_process": "GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0006612 protein targeting to membrane;GO:0006623 protein targeting to vacuole;GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:1904669 ATP export", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q02767-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q02793-1", "uniprot_id": "SKI8_YEAST", "mass": 44232.0, "length": 397, "protein_name": "Antiviral protein SKI8", "gene_name": "SKI8", "organism": "Yeast", "refseq_name": "SKI complex subunit WD repeat protein SKI8", "refseq_ac": "NP_011302", "gene_names_uniprotkb": "SKI8; REC103", "gene_names_refseq": "REC103; SKI8", "protein_names_uniprotkb": "Antiviral protein SKI8; Superkiller protein 8", "protein_names_refseq": "SKI complex subunit WD repeat protein SKI8", "tax_id": 559292, "disease": "", "pathway": " (sce:YGL213C); (R-SCE-429958)", "pathway_count": 2, "publication_count": 24, "publication_id_list": "10744028;11532933;11720286;14562095;14562106;14671320;14992724;15044803;15044957;15152089;15340168;16816949;24374639;3029964;33491328;39304764;6371496;7739557;8442386;9153757;9169869;9258672;9290212;9482746", "class_list": "", "function": "Involved in double-strand break (DSB) formation during meiotic recombination through stabilization of SPO11 association with meiotic chromosome and helping SPO11 to recruit other DSB proteins like REC102 and REC104 to meiotic chromosomes (PubMed:14992724, PubMed:15044957, PubMed:16816949, PubMed:39304764, PubMed:9258672). Also a component of the SKI complex involved in 3'-mRNA degradation pathway (PubMed:11532933, PubMed:11720286, PubMed:7739557, PubMed:9482746). Represses dsRNA virus propagation by specifically blocking translation of viral mRNAs, perhaps recognizing the absence of CAP or poly(A) (PubMed:10744028, PubMed:14671320, PubMed:7739557). Essential for controlling the propagation of M double-stranded RNA (dsRNA) and thus for preventing virus-induced cytopathology (PubMed:3029964, PubMed:6371496)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTU2", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0055087 Ski complex;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000228 nuclear chromosome", "go_biological_process": "GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay;GO:0070481 nuclear-transcribed mRNA catabolic process, non-stop decay;GO:0051607 defense response to virus;GO:0006402 mRNA catabolic process;GO:0000956 nuclear-transcribed mRNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "Q02793-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q02821-1", "uniprot_id": "IMA1_YEAST", "mass": 60441.0, "length": 542, "protein_name": "Importin subunit alpha", "gene_name": "SRP1", "organism": "Yeast", "refseq_name": "karyopherin alpha", "refseq_ac": "NP_014210", "gene_names_uniprotkb": "SRP1; KAP60; N1606", "gene_names_refseq": "KAP60; SCM1; SRP1", "protein_names_uniprotkb": "Importin subunit alpha; Karyopherin subunit alpha; Karyopherin-60; Serine-rich RNA polymerase I suppressor protein", "protein_names_refseq": "karyopherin alpha", "tax_id": 559292, "disease": "hereditary spastic paraplegia 88 (Disease Ontology:DOID:0070457)", "pathway": " (sce:YNL189W)", "pathway_count": 1, "publication_count": 24, "publication_id_list": "10745017;10913188;1448093;14532109;14562106;14648200;15602554;16929305;17330950;19244342;19779198;21075847;22814378;24374639;32597660;33481703;33491328;7565597;7622450;8041713;8521485;9169873;9258433;9695948", "class_list": "", "function": "Functions in nuclear protein import as an adapter protein for importin beta nuclear receptors (PubMed:10913188). Binds specifically and directly to substrates containing either a simple or bipartite NLS motif (PubMed:10745017). Promotes docking of import substrates to the nuclear envelope (PubMed:8521485). Together with importin beta KAP95, mediates nuclear import of transcription factor GCN4 (PubMed:14648200). Together with tethering factor STS1, targets the proteasome to the nucleus (PubMed:10913188, PubMed:21075847)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W0Z8", "ec_number_list": "", "go_molecular_function": "GO:0044877 protein-containing complex binding;GO:0097718 disordered domain specific binding;GO:0008139 nuclear localization sequence binding;GO:0061608 nuclear import signal receptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0006612 protein targeting to membrane;GO:0051170 import into nucleus;GO:0006607 NLS-bearing protein import into nucleus;GO:0006606 protein import into nucleus;GO:0031144 proteasome localization", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "Q02821-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q02825-1", "uniprot_id": "SEN54_YEAST", "mass": 54649.0, "length": 467, "protein_name": "tRNA-splicing endonuclease subunit SEN54", "gene_name": "SEN54", "organism": "Yeast", "refseq_name": "tRNA splicing endonuclease subunit SEN54", "refseq_ac": "NP_015242", "gene_names_uniprotkb": "SEN54; LPF3C", "gene_names_refseq": "SEN54", "protein_names_uniprotkb": "tRNA-splicing endonuclease subunit SEN54; Splicing endonuclease of 54 kDa; tRNA-intron endonuclease SEN54", "protein_names_refseq": "tRNA splicing endonuclease subunit SEN54", "tax_id": 559292, "disease": "pontocerebellar hypoplasia type 2A (Disease Ontology:DOID:0060267); pontocerebellar hypoplasia type 4 (Disease Ontology:DOID:0060273); pontocerebellar hypoplasia type 5 (Disease Ontology:DOID:0060274)", "pathway": " (sce:YPL083C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "12925762;14562106;16823961;24374639;33481703;33491328;9169875;9200603", "class_list": "", "function": "Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. May be required to embody the molecular ruler of the complex., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3T4", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0012505 endomembrane system;GO:0000214 tRNA-intron endonuclease complex", "go_biological_process": "GO:0000379 tRNA-type intron splice site recognition and cleavage", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q02825-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q03012-1", "uniprot_id": "SPP1_YEAST", "mass": 41468.0, "length": 353, "protein_name": "COMPASS component SPP1", "gene_name": "SPP1", "organism": "Yeast", "refseq_name": "Spp1p", "refseq_ac": "NP_015187", "gene_names_uniprotkb": "SPP1; CPS40; SAF41", "gene_names_refseq": "CPS40; SAF41; SPP1", "protein_names_uniprotkb": "COMPASS component SPP1; Complex proteins associated with SET1 protein SPP1; Set1C component SPP1; Suppressor of PRP protein 1", "protein_names_refseq": "Spp1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL138C)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "11687631;11742990;11752412;11805083;14562106;17563356;18407956;19779198;19795423;19823750;23749301;24374639;29071121;30100186;31253666;31922488;32597660;33481703;33491328;9169875", "class_list": "", "function": "Component of the Set1C/COMPASS complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation (PubMed:11742990, PubMed:11752412, PubMed:11805083). COMPASS recognizes ubiquitinated H2B on one face of the nucleosome which stimulates the methylation of H3 on the opposing face (PubMed:31922488). SPP1/CPS40 can recognize methylated histone lysine residue H3K4me3 or unmethylated H3K4 (PubMed:30100186, PubMed:31253666). Stimulates the RNA binding activity of SET1 (PubMed:29071121)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3N0", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0140002 histone H3K4me3 reader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0048188 Set1C/COMPASS complex;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0031509 subtelomeric heterochromatin formation;GO:0006355 regulation of DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription;GO:1903341 regulation of meiotic DNA double-strand break formation", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "Q03012-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q03063-1", "uniprot_id": "DIG1_YEAST", "mass": 49356.0, "length": 452, "protein_name": "Down-regulator of invasive growth 1", "gene_name": "DIG1", "organism": "Yeast", "refseq_name": "Dig1p", "refseq_ac": "NP_015276", "gene_names_uniprotkb": "DIG1; P7102.02; RST1", "gene_names_refseq": "DIG1; RST1", "protein_names_uniprotkb": "Down-regulator of invasive growth 1; Regulator of STE12 protein 1; Regulator of sterile twelve 1", "protein_names_refseq": "Dig1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL049C)", "pathway_count": 1, "publication_count": 30, "publication_id_list": "10825185;12410840;12732146;14562106;15665377;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20489023;20702584;21126336;21177495;22218487;23749301;24374639;24909858;30516470;32597660;33229814;33481703;33491328;8918885;9094309;9169875;9744865;9860980", "class_list": "", "function": "DIG1 and DIG2 are negative regulators of the filamentation and pheromone induced mating program. DIG1 and DIG2 inhibit the transcriptional activity of STE12 by direct protein-protein interaction. DIG1 colocalizes to promoters with STE12 and redistributes with it during induction of filamentation (by butanol) or mating (by pheromone) to program specific genes, but binding of DIG1 to STE12 is reduced by pheromone treatment., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 17, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 17, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 17, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 51, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 17, "binding_glycan_count": 0, "secondary_ac_list": "D6W3W5", "ec_number_list": "", "go_molecular_function": "GO:0003714 transcription corepressor activity", "go_cellular_component": "GO:0005634 nucleus;GO:1990526 Ste12p-Dig1p-Dig2p complex;GO:1990527 Tec1p-Ste12p-Dig1p complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0071444 cellular response to pheromone;GO:0010570 regulation of filamentous growth;GO:0045894 negative regulation of mating-type specific transcription, DNA-templated;GO:2000218 negative regulation of invasive growth in response to glucose limitation", "synthesized_glycan_count": 0, "hit_score": 4.9, "record_id": "Q03063-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q03308-1", "uniprot_id": "VPS16_YEAST", "mass": 92741.0, "length": 798, "protein_name": "Vacuolar protein sorting-associated protein 16", "gene_name": "VPS16", "organism": "Yeast", "refseq_name": "tethering complex subunit VPS16", "refseq_ac": "NP_015280", "gene_names_uniprotkb": "VPS16; VAM9; VPT16", "gene_names_refseq": "CVT15; SVL6; VAM9; VPS16; VPT16", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 16; Vacuolar morphogenesis protein 9; Vacuolar protein-targeting protein 16", "protein_names_refseq": "tethering complex subunit VPS16", "tax_id": 559292, "disease": "dystonia 30 (Disease Ontology:DOID:0060937); lysosomal storage disease (Disease Ontology:DOID:3211)", "pathway": " (sce:YPL045W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562106;16601699;24374639;33491328;8444873;9169875", "class_list": "", "function": "Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology. Required for growth at elevated temperatures. Acts as a component of the HOPS complex that acts during the docking stage of vacuole fusion. HOPS is an effector for the vacuolar Rab GTPase YPT7 and is required for vacuolar SNARE complex assembly. It remains bound to SNARE complexes after vacuole fusion., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3W9;Q03078", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding", "go_cellular_component": "GO:0030897 HOPS complex;GO:0005768 endosome;GO:0005829 cytosol;GO:0031901 early endosome membrane;GO:0033263 CORVET complex", "go_biological_process": "GO:0035542 regulation of SNARE complex assembly;GO:0042144 vacuole fusion, non-autophagic;GO:0016197 endosomal transport;GO:0006895 Golgi to endosome transport;GO:0007033 vacuole organization", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q03308-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q03373-1", "uniprot_id": "DIG2_YEAST", "mass": 36879.0, "length": 323, "protein_name": "Down-regulator of invasive growth 2", "gene_name": "DIG2", "organism": "Yeast", "refseq_name": "Dig2p", "refseq_ac": "NP_010768", "gene_names_uniprotkb": "DIG2; D8035.23; RST2", "gene_names_refseq": "DIG2; RST2", "protein_names_uniprotkb": "Down-regulator of invasive growth 2; Regulator of STE12 protein 2; Regulator of sterile twelve 2", "protein_names_refseq": "Dig2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR480W)", "pathway_count": 1, "publication_count": 30, "publication_id_list": "10825185;12410840;14562106;15665377;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20489023;21177495;22218487;22814378;23749301;24374639;24909858;26953353;27821475;32597660;33229814;33481703;33491328;8918885;9094309;9169867;9744865;9860980", "class_list": "", "function": "DIG2 and DIG1 are negative regulators of the filamentation and pheromone induced mating program. DIG1 and DIG2 inhibit the transcriptional activity of STE12 by direct protein-protein interaction. DIG2 binds to the DNA binding domain (DBD) of STE12 and thus inhibits transcription when overexpressed., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 23, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VTA3", "ec_number_list": "", "go_molecular_function": "GO:0003714 transcription corepressor activity", "go_cellular_component": "GO:0005634 nucleus;GO:1990526 Ste12p-Dig1p-Dig2p complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0071444 cellular response to pheromone;GO:0045894 negative regulation of mating-type specific transcription, DNA-templated;GO:2000218 negative regulation of invasive growth in response to glucose limitation;GO:2000221 negative regulation of pseudohyphal growth", "synthesized_glycan_count": 0, "hit_score": 3.5, "record_id": "Q03373-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q03497-1", "uniprot_id": "STE20_YEAST", "mass": 102362.0, "length": 939, "protein_name": "Serine/threonine-protein kinase STE20", "gene_name": "STE20", "organism": "Yeast", "refseq_name": "mitogen-activated protein kinase kinase kinase kinase STE20", "refseq_ac": "NP_011856", "gene_names_uniprotkb": "STE20", "gene_names_refseq": "STE20", "protein_names_uniprotkb": "Serine/threonine-protein kinase STE20; 2.7.11.1", "protein_names_refseq": "mitogen-activated protein kinase kinase kinase kinase STE20", "tax_id": 559292, "disease": "stroke (Disease Ontology:DOID:0051061); autism spectrum disorder (Disease Ontology:DOID:0060041); non-syndromic X-linked intellectual disability 30 (Disease Ontology:DOID:0112051); Alzheimer's disease (Disease Ontology:DOID:10652); breast cancer (Disease Ontology:DOID:1612); nephroblastoma (Disease Ontology:DOID:2154); brain ischemia (Disease Ontology:DOID:2316); transitional cell carcinoma (Disease Ontology:DOID:2671); ovarian carcinoma (Disease Ontology:DOID:4001); renal cell carcinoma (Disease Ontology:DOID:4450); ureteral obstruction (Disease Ontology:DOID:5199); schizophrenia (Disease Ontology:DOID:5419)", "pathway": " (sce:YHL007C); (R-SCE-2029482); (R-SCE-389359); (R-SCE-3928662); (R-SCE-445144); (R-SCE-5627123); (R-SCE-5687128); (R-SCE-9013406); (R-SCE-9013420); (R-SCE-9013424)", "pathway_count": 10, "publication_count": 52, "publication_id_list": "10359756;10562285;10837245;10970855;11003652;11046150;11940652;12455995;12586692;12588977;12686605;14562106;1464311;15652479;15665377;15743816;15970663;16428446;17287358;17330950;17563356;18407956;19779198;19795423;19823750;20489023;20702584;21126336;21177495;22218487;22814378;23749301;24374639;27821475;30516470;31208443;32597660;33229814;33481703;33491328;7608157;8091229;8421676;8643578;8722766;9003780;9009270;9215628;9388196;9428767;9742399;9774429", "class_list": "", "function": "MAP4K component of the MAPK pathway required for the mating pheromone response, haploid invasive growth and diploid pseudohyphal development. Links the pheromone response G protein beta gamma subunits to downstream signaling components. Needed for mating in haploid cells, induction of a mating-specific gene FUS1, induction of mating-specific morphologies, and pheromone-induced proliferation arrest. Required for the regulation of the actin polarization and bud emergence during cell cycle in G1. Involved in the high osmolarity glycerol (HOG) response. Phosphorylates 'Thr-307' and 'Ser-302' or 'Ser-306' of STE11 and 'Ser-357' of MYO3. Phosphorylates histone H2B to form H2BS10ph during meiosis and H(2)O(2)-induced apoptosis. Its interaction with CDC42 is required for both invasive growth and the formation of pseudohyphae. Its interaction with STE4 is required for the pheromone signaling., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 19, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 19, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 19, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 109, "reported_mutagensis": 8, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 12, "glyco_site_count": 18, "binding_glycan_count": 0, "secondary_ac_list": "D3DKQ8", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;3.6.5.2;2.7.11.17;2.7.11.23;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;2.3.2.26;3.4.-.-;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0003729 mRNA binding;GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0008349 MAP kinase kinase kinase kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0000131 incipient cellular bud site;GO:0043332 mating projection tip", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0010629 negative regulation of gene expression;GO:0035556 intracellular signal transduction;GO:0043065 positive regulation of apoptotic process;GO:0000165 MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 7.3, "record_id": "Q03497-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q03532-1", "uniprot_id": "HAS1_YEAST", "mass": 56717.0, "length": 505, "protein_name": "ATP-dependent RNA helicase HAS1", "gene_name": "HAS1", "organism": "Yeast", "refseq_name": "ATP-dependent RNA helicase HAS1", "refseq_ac": "NP_014017", "gene_names_uniprotkb": "HAS1", "gene_names_refseq": "HAS1", "protein_names_uniprotkb": "ATP-dependent RNA helicase HAS1; 3.6.4.13; Helicase associated with SET1 protein 1", "protein_names_refseq": "ATP-dependent RNA helicase HAS1", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR290C)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "10684247;14574415;15049817;15100437;15242642;15718299;15769876;17287358;18407956;19779198;19795423;19823750;20702584;21126336;23749301;24374639;32597660;33481703;33491328;34965436;9169872;9398665", "class_list": "", "function": "ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 9, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W0B7", "ec_number_list": "3.6.4.13;5.6.2.3;3.6.4.10;3.6.-.-;5.6.2.4;3.6.4.-;5.6.1.4;3.6.4.12;3.6.4.6;5.6.2.5;3.6.1.-;2.3.2.27;3.1.-.-;3.4.24.-;3.6.5.-;2.7.4.3;2.7.11.1;7.2.2.-", "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0016887 ATP hydrolysis activity;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005730 nucleolus;GO:0030687 preribosome, large subunit precursor;GO:0030686 90S preribosome", "go_biological_process": "GO:0042273 ribosomal large subunit biogenesis;GO:0006364 rRNA processing;GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0042274 ribosomal small subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "Q03532-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q03824-1", "uniprot_id": "INP2_YEAST", "mass": 81467.0, "length": 705, "protein_name": "Inheritance of peroxisomes protein 2", "gene_name": "INP2", "organism": "Yeast", "refseq_name": "Inp2p", "refseq_ac": "NP_013886", "gene_names_uniprotkb": "INP2; YM8520.12C", "gene_names_refseq": "INP2", "protein_names_uniprotkb": "Inheritance of peroxisomes protein 2", "protein_names_refseq": "Inp2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR163C)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "14562095;14562106;16678774;18407956;19795423;19823750;23749301;24374639;30516470;32597660;33481703;33491328;9169872", "class_list": "", "function": "Required for peroxisome inheritance. Acts as the peroxisome-specific receptor for the myosin V motor MYO2., [UniProtKB, PubMed]", "predicted_glycosites": 7, "predicted_n_glycosites": 7, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 22, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "D6VZY5", "ec_number_list": "", "go_molecular_function": "GO:0043495 protein-membrane adaptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005778 peroxisomal membrane", "go_biological_process": "GO:0045033 peroxisome inheritance", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q03824-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q03834-1", "uniprot_id": "MSH6_YEAST", "mass": 140080.0, "length": 1242, "protein_name": "DNA mismatch repair protein MSH6", "gene_name": "MSH6", "organism": "Yeast", "refseq_name": "mismatch repair ATPase MSH6", "refseq_ac": "NP_010382", "gene_names_uniprotkb": "MSH6; PMS3; YD8557.04C", "gene_names_refseq": "MSH6; PMS3; PMS6", "protein_names_uniprotkb": "DNA mismatch repair protein MSH6; MutS protein homolog 6; Postmeiotic segregation protein 3", "protein_names_refseq": "mismatch repair ATPase MSH6", "tax_id": 559292, "disease": "hereditary nonpolyposis colorectal cancer type 5 (Disease Ontology:DOID:0070272); colorectal carcinoma (Disease Ontology:DOID:0080199); mismatch repair cancer syndrome (Disease Ontology:DOID:0112182); urinary bladder cancer (Disease Ontology:DOID:11054); endometrial cancer (Disease Ontology:DOID:1380); breast cancer (Disease Ontology:DOID:1612); cancer (Disease Ontology:DOID:162); ovarian cancer (Disease Ontology:DOID:2394); osteosarcoma (Disease Ontology:DOID:3347); breast carcinoma (Disease Ontology:DOID:3459); Lynch syndrome (Disease Ontology:DOID:3883); primary ovarian insufficiency (Disease Ontology:DOID:5426)", "pathway": " (sce:YDR097C); (R-SCE-5358565)", "pathway_count": 2, "publication_count": 54, "publication_id_list": "10066781;10347163;10480869;10518225;10537275;10615127;10970737;11005803;11062484;11237611;11641390;11986324;12435741;12509278;12820877;14562095;14562106;15513922;15746000;15811858;16214425;16337600;16407100;16600868;16702432;17141577;17157869;17287358;17330950;17563356;17567610;17573527;18407956;19520826;19684113;19779198;20190278;20702584;21126336;22031224;23749301;24374639;30516470;32597660;33481703;33491328;8600025;8723353;8816473;9111357;9169867;9545323;9770499;9819445", "class_list": "", "function": "Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. MSH6 provides substrate-binding and substrate specificity to the complex. When bound, MutS alpha bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair base-base and single insertion-deletion mismatches that occur during replication, but can also repair longer insertion-deletion loops (IDLs), although with decreasing efficiency as the size of the extrahelical loop increases. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis by the MutS alpha complex is crucial for MMR. Both subunits bind ATP, but with differing affinities, and their ATPase kinetics are also very different. MSH6 binds and hydrolyzes ATP rapidly, whereas MSH2 catalyzes ATP at a substantially slower rate. Binding to a mismatched base pair suppresses MSH6-catalyzed ATP hydrolysis, but not the activity of MSH2. ATP binding to both subunits is necessary to trigger a change in MutS alpha interaction with mismatched DNA, converting MutS alpha into a sliding clamp capable of hydrolysis-independent movement along DNA, and also facilitates formation of ternary complexes containing MutS and MutL proteins and the mismatch. May also be involved in resolution of recombination intermediates., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 48, "reported_mutagensis": 29, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 12, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VS82", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003676 nucleic acid binding;GO:0000400 four-way junction DNA binding;GO:0030983 mismatched DNA binding", "go_cellular_component": "GO:0032301 MutSalpha complex;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0000710 meiotic mismatch repair;GO:0006298 mismatch repair;GO:0036297 interstrand cross-link repair;GO:0043111 replication fork arrest", "synthesized_glycan_count": 0, "hit_score": 5.5, "record_id": "Q03834-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q03835-1", "uniprot_id": "GLRX3_YEAST", "mass": 28261.0, "length": 250, "protein_name": "Monothiol glutaredoxin-3", "gene_name": "GRX3", "organism": "Yeast", "refseq_name": "monothiol glutaredoxin GRX3", "refseq_ac": "NP_010383", "gene_names_uniprotkb": "GRX3; YD8557.05C", "gene_names_refseq": "GRX3", "protein_names_uniprotkb": "Monothiol glutaredoxin-3", "protein_names_refseq": "monothiol glutaredoxin GRX3", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR098C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562106;18281282;18703840;19715344;24374639;9169867", "class_list": "", "function": "Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters (By similarity). Binds one iron-sulfur cluster per dimer. The iron-sulfur cluster is bound between subunits, and is complexed by a bound glutathione and a cysteine residue from each subunit (Probable)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS83", "ec_number_list": "", "go_molecular_function": "GO:0015036 disulfide oxidoreductase activity;GO:0046872 metal ion binding;GO:0051537 2 iron, 2 sulfur cluster binding;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding;GO:0051536 iron-sulfur cluster binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:1990229 iron-sulfur cluster assembly complex", "go_biological_process": "GO:0016226 iron-sulfur cluster assembly;GO:0006879 intracellular iron ion homeostasis;GO:0030036 actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q03835-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q03898-1", "uniprot_id": "FIN1_YEAST", "mass": 33186.0, "length": 291, "protein_name": "Filament protein FIN1", "gene_name": "FIN1", "organism": "Yeast", "refseq_name": "Fin1p", "refseq_ac": "NP_010415", "gene_names_uniprotkb": "FIN1; YD9302.05C", "gene_names_refseq": "FIN1", "protein_names_uniprotkb": "Filament protein FIN1; Filaments in between nuclei protein 1", "protein_names_refseq": "Fin1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR130C)", "pathway_count": 1, "publication_count": 23, "publication_id_list": "11929974;11931638;12551942;14574415;17173039;17287358;17322287;17563356;18407956;19779198;19795423;19823750;19948764;20489023;20702584;21126336;21177495;23749301;24374639;32597660;33481703;33491328;9169867", "class_list": "", "function": "Forms cell-cycle specific filaments between the spindle pole bodies of dividing yeast cells., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 21, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSB6", "ec_number_list": "", "go_molecular_function": "GO:0005200 structural constituent of cytoskeleton;GO:0008017 microtubule binding", "go_cellular_component": "GO:0000164 protein phosphatase type 1 complex;GO:0000235 astral microtubule;GO:0000922 spindle pole;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:1902426 deactivation of mitotic spindle assembly checkpoint;GO:0007052 mitotic spindle organization;GO:0045104 intermediate filament cytoskeleton organization;GO:0000070 mitotic sister chromatid segregation;GO:0034501 protein localization to kinetochore", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "Q03898-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q03940-1", "uniprot_id": "RUVB1_YEAST", "mass": 50453.0, "length": 463, "protein_name": "RuvB-like protein 1", "gene_name": "RVB1", "organism": "Yeast", "refseq_name": "RuvB family ATP-dependent DNA helicase pontin", "refseq_ac": "NP_010476", "gene_names_uniprotkb": "RVB1; TIH1; TIP49A", "gene_names_refseq": "RVB1; TIH1; TIP49A; TIP49", "protein_names_uniprotkb": "RuvB-like protein 1; 3.6.4.12; RUVBL1; TIP49-homology protein 1; TIP49a homolog", "protein_names_refseq": "RuvB family ATP-dependent DNA helicase pontin", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR190C)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "10787406;10952318;11278922;12576485;14562095;14562106;14645854;14690591;14690608;15045029;15525518;15766533;18407956;21126336;22814378;24374639;33481703;33491328;9169867", "class_list": "", "function": "DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes. Its ability to induce transcription of some phosphate-responsive genes is modulated by inositol polyphosphates. The INO80 complex is involved in DNA repair by associating to 'Ser-129' phosphorylated H2A histones as a response to DNA damage. RVB1 recruits ARP5 to the INO80 complex. During transcription may recruit SPT15/TBP to the TATA-boxes of involved genes. Required for box C/D and box H/ACA snoRNA accumulation and involved in pre-rRNA processing., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSH3", "ec_number_list": "3.6.4.13;5.6.2.3;3.6.4.10;3.6.-.-;5.6.2.4;3.6.4.-;5.6.1.4;3.6.4.12;3.6.4.6;5.6.2.5;3.6.1.-;2.3.2.27;3.1.-.-;3.4.24.-;3.6.5.-;2.7.4.3;2.7.11.1;7.2.2.-", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003678 DNA helicase activity;GO:0043139 5'-3' DNA helicase activity", "go_cellular_component": "GO:0097255 R2TP complex;GO:0005634 nucleus;GO:0031011 Ino80 complex;GO:0035267 NuA4 histone acetyltransferase complex;GO:0000785 chromatin", "go_biological_process": "GO:0006281 DNA repair;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "Q03940-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04048-1", "uniprot_id": "SYF1_YEAST", "mass": 100229.0, "length": 859, "protein_name": "Pre-mRNA-splicing factor SYF1", "gene_name": "SYF1", "organism": "Yeast", "refseq_name": "mRNA splicing protein SYF1", "refseq_ac": "NP_010704", "gene_names_uniprotkb": "SYF1; NTC90", "gene_names_refseq": "NTC90; SYF1", "protein_names_uniprotkb": "Pre-mRNA-splicing factor SYF1; PRP19-associated complex protein 90; Synthetic lethal with CDC40 protein 1", "protein_names_refseq": "mRNA splicing protein SYF1", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR416W); (R-SCE-6782135); (R-SCE-6782210)", "pathway_count": 3, "publication_count": 12, "publication_id_list": "11102353;11105756;11842115;11884590;12088152;14562095;14562106;14690591;22814378;24374639;33491328;9169867", "class_list": "", "function": "Involved in pre-mRNA splicing and cell cycle control. As a component of the NTC complex (or PRP19-associated complex), associates to the spliceosome to mediate conformational rearrangement or to stabilize the structure of the spliceosome after U4 snRNA dissociation, which leads to spliceosome maturation., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VT47", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0071014 post-mRNA release spliceosomal complex;GO:0071006 U2-type catalytic step 1 spliceosome;GO:0071007 U2-type catalytic step 2 spliceosome", "go_biological_process": "GO:0000349 generation of catalytic spliceosome for first transesterification step;GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q04048-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04049-1", "uniprot_id": "POLH_YEAST", "mass": 71515.0, "length": 632, "protein_name": "DNA polymerase eta", "gene_name": "RAD30", "organism": "Yeast", "refseq_name": "DNA-directed DNA polymerase eta", "refseq_ac": "NP_010707", "gene_names_uniprotkb": "RAD30; DBH1", "gene_names_refseq": "DBH1; RAD30", "protein_names_uniprotkb": "DNA polymerase eta; 2.7.7.7; Radiation-sensitive protein 30", "protein_names_refseq": "DNA-directed DNA polymerase eta", "tax_id": 559292, "disease": "xeroderma pigmentosum (Disease Ontology:DOID:0050427); female breast cancer (Disease Ontology:DOID:0050671); xeroderma pigmentosum variant type (Disease Ontology:DOID:0110847)", "pathway": " (sce:YDR419W)", "pathway_count": 1, "publication_count": 44, "publication_id_list": "10347143;10601233;10713149;10725365;10924462;10932195;11027270;11054429;11062246;11113193;11238937;11545742;11545743;11861920;12110599;12665597;12692307;12888515;12899630;14527996;14562095;14562106;15024063;15157108;15284331;15333698;15520252;15544332;15725627;15743815;15779911;16181813;16366567;16387871;16415180;16866379;23747975;24374639;33033113;33229814;33491328;9169867;9409821;9974380", "class_list": "", "function": "DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. Efficiently incorporates nucleotides opposite to other UV or oxidative DNA damages like O(6)-methylguanine, 7,8-dihydro-8-oxoguanine, 2,6-diamino-4-hydroxy-5-formamidopyrimidine of 2'-deoxyguanosine (FaPydG), or p-benzoquinone DNA adducts., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 5, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 5, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 5, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 5, "reported_mutagensis": 11, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 3, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "D6VT49", "ec_number_list": "2.7.7.7;3.1.26.4;2.7.7.49;3.4.23.-;3.1.11.-", "go_molecular_function": "GO:0003887 DNA-directed DNA polymerase activity;GO:0008270 zinc ion binding;GO:0003684 damaged DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0035861 site of double-strand break;GO:0005657 replication fork", "go_biological_process": "GO:0006281 DNA repair;GO:0007059 chromosome segregation;GO:0009314 response to radiation;GO:0007064 mitotic sister chromatid cohesion;GO:0042276 error-prone translesion synthesis", "synthesized_glycan_count": 0, "hit_score": 5.1, "record_id": "Q04049-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04199-1", "uniprot_id": "CAF1B_YEAST", "mass": 51252.0, "length": 468, "protein_name": "Chromatin assembly factor 1 subunit B", "gene_name": "CAC2", "organism": "Yeast", "refseq_name": "Cac2p", "refseq_ac": "NP_013605", "gene_names_uniprotkb": "CAC2", "gene_names_refseq": "CAC2", "protein_names_uniprotkb": "Chromatin assembly factor 1 subunit B; CAF-1 60 kDa subunit; CAF-1 subunit B; Chromatin assembly factor 1 subunit p60", "protein_names_refseq": "Cac2p", "tax_id": 559292, "disease": "oral squamous cell carcinoma (Disease Ontology:DOID:0050866); prostate cancer (Disease Ontology:DOID:10283); glioblastoma (Disease Ontology:DOID:3068); high grade glioma (Disease Ontology:DOID:3070); skin melanoma (Disease Ontology:DOID:8923)", "pathway": " (sce:YML102W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562106;19683497;24374639;33491328;9030687;9169872", "class_list": "", "function": "Acts as a component of the histone chaperone complex chromatin assembly factor 1 (CAF-1), which assembles histone octamers onto replicating DNA (PubMed:9030687). It performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer (By similarity). Plays a role in the maintenance of heterochromatin (By similarity)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W0I2", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0000775 chromosome, centromeric region;GO:0033186 CAF-1 complex", "go_biological_process": "GO:0006281 DNA repair;GO:0006260 DNA replication;GO:0006325 chromatin organization;GO:0006334 nucleosome assembly;GO:0006335 DNA replication-dependent chromatin assembly", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q04199-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04228-1", "uniprot_id": "UBX2_YEAST", "mass": 66761.0, "length": 584, "protein_name": "UBX domain-containing protein 2", "gene_name": "UBX2", "organism": "Yeast", "refseq_name": "Ubx2p", "refseq_ac": "NP_013699", "gene_names_uniprotkb": "UBX2; SEL1; YM9571.05", "gene_names_refseq": "SEL1; UBX2", "protein_names_uniprotkb": "UBX domain-containing protein 2; Secretion lowering protein 1", "protein_names_refseq": "Ubx2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YML013W); (R-SCE-6798695); (R-SCE-8980692)", "pathway_count": 3, "publication_count": 13, "publication_id_list": "14562095;14562106;15258615;16179952;16179953;16873066;21177495;23749301;24374639;32597660;33481703;33491328;9169872", "class_list": "", "function": "Integral endoplasmic reticulum membrane protein that coordinates the assembly of the ER-associated protein degradation (ERAD) machinery at the ER membrane. Mediates binding of CDC48 to the E3 ubiquitin ligases SSM4/DOA10 and HRD1, and to ERAD substrates. Component of the DOA10 ubiquitin ligase complex, which is part of the ERAD-C pathway responsible for the rapid degradation of membrane proteins with misfolded cytoplasmic domains. ERAD-C substrates are ubiquitinated through DOA10 in conjunction with the E2 ubiquitin-conjugating enzymes UBC6 and UBC7-CUE1. Also a component of the HRD1 ubiquitin ligase complex, which is part of the ERAD-L and ERAD-M pathways responsible for the rapid degradation of soluble lumenal and membrane proteins with misfolded lumenal domains (ERAD-L), or ER-membrane proteins with misfolded transmembrane domains (ERAD-M). ERAD-L substrates are ubiquitinated through HRD1 in conjunction with the E2 ubiquitin-conjugating enzymes UBC1 and UBC7-CUE1. Ubiquitinated substrates are then removed to the cytosol via the action of the CDC48-NPL4-UFD1 ATPase complex and targeted to the proteasome., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZG1", "ec_number_list": "", "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005783 endoplasmic reticulum;GO:0005811 lipid droplet;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0036503 ERAD pathway;GO:0072671 mitochondria-associated ubiquitin-dependent protein catabolic process;GO:0034982 mitochondrial protein processing;GO:0034389 lipid droplet organization", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q04228-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04311-1", "uniprot_id": "VMS1_YEAST", "mass": 72733.0, "length": 632, "protein_name": "tRNA endonuclease VMS1", "gene_name": "VMS1", "organism": "Yeast", "refseq_name": "Vms1p", "refseq_ac": "NP_010334", "gene_names_uniprotkb": "VMS1", "gene_names_refseq": "VMS1", "protein_names_uniprotkb": "tRNA endonuclease VMS1; 3.1.-.-; VCP/CDC48-associated mitochondrial stress-responsive protein 1", "protein_names_refseq": "Vms1p", "tax_id": 559292, "disease": "inflammatory bowel disease (Disease Ontology:DOID:0050589)", "pathway": " (sce:YDR049W)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "14562095;14562106;17322287;19684113;21070972;21148305;24374639;29632312;29875445;31011209;31189955;33491328;9169867;9171100", "class_list": "", "function": "Endonuclease that cleaves polypeptidyl-tRNAs downstream of the ribosome-associated quality control (RQC) pathway to release incompletely synthesized polypeptides for degradation (PubMed:21148305, PubMed:29632312, PubMed:29875445, PubMed:31011209, PubMed:31189955). The RQC pathway disassembles aberrantly stalled translation complexes to recycle or degrade the constituent parts (PubMed:29632312, PubMed:29875445, PubMed:31011209, PubMed:31189955). VMS1 acts downstream disassembly of stalled ribosomes and specifically cleaves off the terminal 3'-CCA nucleotides universal to all tRNAs from polypeptidyl-tRNAs, releasing (1) ubiquitinated polypeptides from 60S ribosomal subunit for degradation by the ERAD pathway and (2) cleaved tRNAs for recycling (PubMed:29632312, PubMed:31011209, PubMed:31189955). Component of an evolutionarily conserved system for ubiquitin-mediated mitochondria-associated protein degradation (MAD), which is necessary to maintain mitochondrial, cellular, and organismal viability (PubMed:21070972)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 13, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS36;Q66RH0", "ec_number_list": "", "go_molecular_function": "GO:0004045 peptidyl-tRNA hydrolase activity;GO:0008270 zinc ion binding;GO:0004521 RNA endonuclease activity;GO:0140101 catalytic activity, acting on a tRNA", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0005789 endoplasmic reticulum membrane;GO:0036266 Cdc48p-Npl4p-Vms1p AAA ATPase complex", "go_biological_process": "GO:0072344 rescue of stalled ribosome;GO:0036503 ERAD pathway;GO:0071630 nuclear protein quality control by the ubiquitin-proteasome system;GO:0072671 mitochondria-associated ubiquitin-dependent protein catabolic process;GO:0006515 protein quality control for misfolded or incompletely synthesized proteins", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q04311-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04372-1", "uniprot_id": "TAP42_YEAST", "mass": 42568.0, "length": 366, "protein_name": "Type 2A phosphatase-associated protein 42", "gene_name": "TAP42", "organism": "Yeast", "refseq_name": "Tap42p", "refseq_ac": "NP_013741", "gene_names_uniprotkb": "TAP42; YM9711.18; YM9973.01C", "gene_names_refseq": "TAP42", "protein_names_uniprotkb": "Type 2A phosphatase-associated protein 42", "protein_names_refseq": "Tap42p", "tax_id": 559292, "disease": "corpus callosum agenesis-intellectual disability-coloboma-micrognathia syndrome (Disease Ontology:DOID:0060816)", "pathway": " (sce:YMR028W)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10329624;11741537;12697813;12820961;14551259;15470255;17322287;19779198;24374639;33481703;33491328;8756348;9169872", "class_list": "", "function": "Involved in negative regulation of the TOR signaling pathway in response to type of available nitrogen source. Inhibitor of PP2A phosphatase SIT4, which results in inhibition of nuclear export of MSN2, due to lack of dephosphorylation by SIT4. Also required for rapamycin induced activation of expression of many nitrogen discrimination pathway (NDP) genes. In complex with PPH21, required for organization of the actin cytoskeletom during the cell cycle via a Rho GTPase-dependent mechanism., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZK2;Q05039", "ec_number_list": "", "go_molecular_function": "GO:0051721 protein phosphatase 2A binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0035303 regulation of dephosphorylation;GO:0031929 TOR signaling;GO:0009968 negative regulation of signal transduction;GO:0045943 positive regulation of transcription by RNA polymerase I;GO:1903432 regulation of TORC1 signaling", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q04372-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04410-1", "uniprot_id": "GRH1_YEAST", "mass": 41119.0, "length": 372, "protein_name": "GRASP65 homolog protein 1", "gene_name": "GRH1", "organism": "Yeast", "refseq_name": "Grh1p", "refseq_ac": "NP_010805", "gene_names_uniprotkb": "GRH1", "gene_names_refseq": "GRH1", "protein_names_uniprotkb": "GRASP65 homolog protein 1", "protein_names_refseq": "Grh1p", "tax_id": 559292, "disease": "obesity (Disease Ontology:DOID:9970)", "pathway": " (sce:YDR517W); (R-SCE-162658)", "pathway_count": 2, "publication_count": 19, "publication_id_list": "10417390;14562095;14562106;16269340;17261844;17330950;17563356;18407956;19779198;20702584;21126336;21177495;22218487;23749301;24374639;32597660;33481703;33491328;9169867", "class_list": "", "function": "Involved in the spindle assembly checkpoint. Involved in ER to Golgi vesicle-mediated transport by either facilitating USO1-dependent and -independent tethering or increasing target accuracy of fusion events of COPII-coated vesicles., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VTD8", "ec_number_list": "", "go_molecular_function": "GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0005801 cis-Golgi network", "go_biological_process": "GO:1990000 amyloid fibril formation;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0009306 protein secretion;GO:0009267 cellular response to starvation;GO:0007030 Golgi organization", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "Q04410-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04636-1", "uniprot_id": "POB3_YEAST", "mass": 62994.0, "length": 552, "protein_name": "FACT complex subunit POB3", "gene_name": "POB3", "organism": "Yeast", "refseq_name": "FACT complex subunit POB3", "refseq_ac": "NP_013642", "gene_names_uniprotkb": "POB3", "gene_names_refseq": "POB3", "protein_names_uniprotkb": "FACT complex subunit POB3; Facilitates chromatin transcription complex subunit POB3", "protein_names_refseq": "FACT complex subunit POB3", "tax_id": 559292, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (sce:YML069W); (R-SCE-674695); (R-SCE-6796648); (R-SCE-6804756)", "pathway_count": 4, "publication_count": 30, "publication_id_list": "10413469;10817755;10924459;11313475;11432837;11927560;12242279;12524332;12682017;12934008;12952948;14562106;14585989;14739930;15082784;15987999;16678108;17287358;17563356;18407956;19683497;23749301;24374639;32597660;33481703;33491328;9169872;9199353;9705338;9832518", "class_list": "", "function": "Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. Transcription elongation is promoted by the repression of transcription initiation from cryptic sites. Also acts in establishing transcription initiation complexes and promotes SPT15/TBP-binding to a TATA box. Together with replication factor-A protein (RPA), FACT may play a role in nucleosome deposition during DNA replication., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 11, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZA4", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0000785 chromatin;GO:0035101 FACT complex", "go_biological_process": "GO:0034728 nucleosome organization;GO:0006281 DNA repair;GO:0006351 DNA-templated transcription;GO:0006325 chromatin organization;GO:0045899 positive regulation of RNA polymerase II transcription preinitiation complex assembly", "synthesized_glycan_count": 0, "hit_score": 3.1, "record_id": "Q04636-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04712-1", "uniprot_id": "RRN11_YEAST", "mass": 59254.0, "length": 507, "protein_name": "RNA polymerase I-specific transcription initiation factor RRN11", "gene_name": "RRN11", "organism": "Yeast", "refseq_name": "Rrn11p", "refseq_ac": "NP_013669", "gene_names_uniprotkb": "RRN11; YM9827.09C", "gene_names_refseq": "RRN11", "protein_names_uniprotkb": "RNA polymerase I-specific transcription initiation factor RRN11", "protein_names_refseq": "Rrn11p", "tax_id": 559292, "disease": "", "pathway": " (sce:YML043C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562095;14562106;17322287;19779198;24374639;7958901;8702872;8887672;9169872", "class_list": "", "function": "Acts as a component of the core factor (CF) complex which is essential for the initiation of rDNA transcription by RNA polymerase I. After binding of UAF (upstream activation factor) to an upstream element of the promoter, CF is recruited in a SPT15/TBP-dependent manner to form a preinitiation complex., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZD2", "ec_number_list": "", "go_molecular_function": "GO:0017025 TBP-class protein binding;GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding;GO:0001181 RNA polymerase I general transcription initiation factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0070860 RNA polymerase I core factor complex", "go_biological_process": "GO:0042790 nucleolar large rRNA transcription by RNA polymerase I", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q04712-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04839-1", "uniprot_id": "GFD1_YEAST", "mass": 21571.0, "length": 188, "protein_name": "mRNA transport factor GFD1", "gene_name": "GFD1", "organism": "Yeast", "refseq_name": "Gfd1p", "refseq_ac": "NP_013982", "gene_names_uniprotkb": "GFD1; YM9920.09", "gene_names_refseq": "GFD1", "protein_names_uniprotkb": "mRNA transport factor GFD1; Good for full DBP5 activity protein 1", "protein_names_refseq": "Gfd1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR255W)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "10523319;10610322;14562106;15208322;15619606;15665377;17330950;18407956;19779198;19795423;19823750;20702584;21177495;22218487;23749301;24374639;30516470;32597660;33481703;33491328;9169872;9698782", "class_list": "", "function": "High-copy suppressor of mutant alleles of ATP-dependent RNA helicase DBP5, which is involved in mRNA export from the nucleus. It may also play an important role in a late stage of NAB2-mRNA export., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W081", "ec_number_list": "", "go_molecular_function": "GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0005643 nuclear pore;GO:0005737 cytoplasm;GO:0031965 nuclear membrane", "go_biological_process": "GO:0006406 mRNA export from nucleus;GO:0015031 protein transport", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "Q04839-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04934-1", "uniprot_id": "IVY1_YEAST", "mass": 49976.0, "length": 453, "protein_name": "Protein IVY1", "gene_name": "IVY1", "organism": "Yeast", "refseq_name": "Ivy1p", "refseq_ac": "NP_010515", "gene_names_uniprotkb": "IVY1; YD9934.14", "gene_names_refseq": "IVY1", "protein_names_uniprotkb": "Protein IVY1; Interaction with VPS33 and YPT7 protein 1", "protein_names_refseq": "Ivy1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR229W)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "12553664;14562106;15665377;17330950;17563356;18407956;19684113;19779198;20702584;21126336;21177495;22814378;23749301;24374639;30516470;32597660;33481703;33491328;9169867", "class_list": "", "function": "May be required for vacuolar fusion. Overexpression leads to fragmentation of vacuoles, missorting of the vacuolar enzyme carboxypeptidase Y (CPY) to the exterior of the cell and accumulation of multivesicular bodies inside the cell., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 38, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSL1", "ec_number_list": "", "go_molecular_function": "GO:0005543 phospholipid binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0045121 membrane raft;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0042144 vacuole fusion, non-autophagic", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "Q04934-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04964-1", "uniprot_id": "SML1_YEAST", "mass": 11834.0, "length": 104, "protein_name": "Ribonucleotide reductase inhibitor protein SML1", "gene_name": "SML1", "organism": "Yeast", "refseq_name": "ribonucleotide reductase inhibiting protein SML1", "refseq_ac": "NP_013653", "gene_names_uniprotkb": "SML1; YM9958.04", "gene_names_refseq": "SML1", "protein_names_uniprotkb": "Ribonucleotide reductase inhibitor protein SML1", "protein_names_refseq": "ribonucleotide reductase inhibiting protein SML1", "tax_id": 559292, "disease": "", "pathway": " (sce:YML058W)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "10593972;11904430;14562106;14684746;15222768;17322287;18832349;20566477;21177495;22218487;22814378;23749301;24374639;33481703;33491328;9169872", "class_list": "", "function": "Strong inhibitor of ribonucleotide reductase (RNR1) and is involved in regulating dNTP production., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZB6", "ec_number_list": "", "go_molecular_function": "GO:1990846 ribonucleoside-diphosphate reductase inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006974 DNA damage response;GO:0007005 mitochondrion organization;GO:0008156 negative regulation of DNA replication", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q04964-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05080-1", "uniprot_id": "CYK2_YEAST", "mass": 76207.0, "length": 669, "protein_name": "Cytokinesis protein 2", "gene_name": "HOF1", "organism": "Yeast", "refseq_name": "formin-binding protein HOF1", "refseq_ac": "NP_013746", "gene_names_uniprotkb": "HOF1; CYK2; YM9973.05", "gene_names_refseq": "CYK2; HOF1", "protein_names_uniprotkb": "Cytokinesis protein 2; Homolog of CDC15 protein 1", "protein_names_refseq": "formin-binding protein HOF1", "tax_id": 559292, "disease": "", "pathway": " (sce:YMR032W)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "14562106;18344988;18407956;19528296;19779198;21177495;21498574;23447700;23749301;24374639;33481703;33491328;9169872;9864366", "class_list": "", "function": "Throughout most of the cell cycle it forms a double ring that coincides with the septins. After the onset of mitosis, forms a ring-like structure which colocalizes with the medial actin ring. Mediates cytoskeletal rearrangements required for cytokinesis. In conjunction with the medial actin ring exhibits contraction-like action., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 35, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZK6", "ec_number_list": "", "go_molecular_function": "GO:0005543 phospholipid binding;GO:0042802 identical protein binding;GO:0051015 actin filament binding;GO:0044877 protein-containing complex binding;GO:0008092 cytoskeletal protein binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0016020 membrane;GO:0030427 site of polarized growth", "go_biological_process": "GO:0051017 actin filament bundle assembly;GO:0007010 cytoskeleton organization;GO:0000281 mitotic cytokinesis;GO:0051126 negative regulation of actin nucleation;GO:0032465 regulation of cytokinesis", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q05080-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05583-1", "uniprot_id": "CIAO1_YEAST", "mass": 37275.0, "length": 330, "protein_name": "Cytosolic iron-sulfur protein assembly protein 1", "gene_name": "CIA1", "organism": "Yeast", "refseq_name": "iron-sulfur cluster assembly protein CIA1", "refseq_ac": "NP_010553", "gene_names_uniprotkb": "CIA1", "gene_names_refseq": "CIA1", "protein_names_uniprotkb": "Cytosolic iron-sulfur protein assembly protein 1", "protein_names_refseq": "iron-sulfur cluster assembly protein CIA1", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR267C)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14562095;14562106;16314508;17937914;24374639;9169867", "class_list": "", "function": "Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins., [UniProtKB, HAMAP, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSQ1", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0097361 cytosolic [4Fe-4S] assembly targeting complex;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0016226 iron-sulfur cluster assembly;GO:0002098 tRNA wobble uridine modification", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q05583-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05789-1", "uniprot_id": "ATG38_YEAST", "mass": 25975.0, "length": 226, "protein_name": "PtdIns3K complex I subunit atg38", "gene_name": "ATG38", "organism": "Yeast", "refseq_name": "Atg38p", "refseq_ac": "NP_013312", "gene_names_uniprotkb": "ATG38; L8167.20", "gene_names_refseq": "ATG38", "protein_names_uniprotkb": "PtdIns3K complex I subunit atg38; Autophagy-related protein 38", "protein_names_refseq": "Atg38p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR211C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "10734188;14562095;22814378;24165940;24374639;27630019;33481703;33491328;9169871", "class_list": "", "function": "Autophagy-related protein required for cytoplasm to vacuole transport (Cvt) and autophagy as a part of the autophagy-specific VPS34 PI3-kinase complex I (PubMed:24165940). This complex is essential to recruit the ATG8-phosphatidylinositol conjugate and the ATG12-ATG5 conjugate to the pre-autophagosomal structure (PubMed:24165940). ATG38 is required for the integrity of the active PI3-kinase complex I by maintaining an association between VPS15-VPS34 and ATG14-VPS30 subcomplexes (PubMed:24165940)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYL2", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0005198 structural molecule activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005774 vacuolar membrane;GO:0034045 phagophore assembly site membrane;GO:0000407 phagophore assembly site;GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I", "go_biological_process": "GO:0016236 macroautophagy;GO:0006914 autophagy;GO:0046854 phosphatidylinositol phosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q05789-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05949-1", "uniprot_id": "BUR2_YEAST", "mass": 45721.0, "length": 395, "protein_name": "Protein BUR2", "gene_name": "BUR2", "organism": "Yeast", "refseq_name": "Bur2p", "refseq_ac": "NP_013327", "gene_names_uniprotkb": "BUR2; CST4", "gene_names_refseq": "BUR2; CST4", "protein_names_uniprotkb": "Protein BUR2; Bypass UAS requirement protein 2; Chromosome stability protein 4", "protein_names_refseq": "Bur2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR226W); (R-SCE-674695); (R-SCE-6796648); (R-SCE-6807505); (R-SCE-9018519)", "pathway_count": 5, "publication_count": 13, "publication_id_list": "10454593;10982824;14562095;14562106;16040246;18407956;23749301;24374639;32597660;33481703;33491328;8293972;9169871", "class_list": "", "function": "Component of the BUR kinase complex involved in transcription regulation. This complex phosphorylates 'Ser-120' of the UBC2/RAD6 ubiquitin-conjugating enzyme (E2), leading to monoubiquitination of histone H2B, the localization of the PAF1 complex to the chromatin, and the silencing of telomeric-associated genes. Also required for histone H3 'Lys-4' trimethylation. May phosphorylate the 'Ser-5' of the RBP1 carboxy-terminal domain (CTD) repeats. Necessary for the recovery from pheromone-induced growth arrest in the cell cycle G1 phase. Also required for vegetative growth itself. The kinase activity of the complex requires the presence of BUR2. Overexpression of BUR2 interferes with mitotic chromosome segregation., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYM6", "ec_number_list": "", "go_molecular_function": "GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity;GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000307 cyclin-dependent protein kinase holoenzyme complex;GO:0008024 cyclin/CDK positive transcription elongation factor complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006368 transcription elongation by RNA polymerase II;GO:0006353 DNA-templated transcription termination;GO:0032786 positive regulation of DNA-templated transcription, elongation", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q05949-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06032-1", "uniprot_id": "CST9_YEAST", "mass": 53863.0, "length": 482, "protein_name": "Chromosome stability protein 9", "gene_name": "CST9", "organism": "Yeast", "refseq_name": "SUMO ligase CST9", "refseq_ac": "NP_013498", "gene_names_uniprotkb": "CST9; ZIP3", "gene_names_refseq": "CST9; ZIP3", "protein_names_uniprotkb": "Chromosome stability protein 9; Molecular zipper protein 3", "protein_names_refseq": "SUMO ligase CST9", "tax_id": 559292, "disease": "spermatogenic failure (Disease Ontology:DOID:0111910)", "pathway": " (sce:YLR394W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10454593;10943844;15035982;15070750;15805472;24374639;33502312;9169871", "class_list": "", "function": "Component of the synapsis initiation complex (SIC) necessary for the synaptonemal complex assembly. Stabilizes the ZIP2 component to the chromosomes. The SIC complex loads onto chromosomes and nucleates ZIP1 polymerization, a molecular zipper that acts to bring homologous chromosomes in close apposition, which is required for meiotic crossover. May also be involved in double strand break repair., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ29", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0019789 SUMO transferase activity", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0000775 chromosome, centromeric region;GO:0035861 site of double-strand break;GO:0000228 nuclear chromosome;GO:0000795 synaptonemal complex", "go_biological_process": "GO:0016925 protein sumoylation;GO:0007130 synaptonemal complex assembly;GO:0000724 double-strand break repair via homologous recombination;GO:0007129 homologous chromosome pairing at meiosis;GO:0007131 reciprocal meiotic recombination", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q06032-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06078-1", "uniprot_id": "UTP21_YEAST", "mass": 104791.0, "length": 939, "protein_name": "U3 small nucleolar RNA-associated protein 21", "gene_name": "UTP21", "organism": "Yeast", "refseq_name": "rRNA-processing protein UTP21", "refseq_ac": "NP_013513", "gene_names_uniprotkb": "UTP21; L8084.22", "gene_names_refseq": "UTP21", "protein_names_uniprotkb": "U3 small nucleolar RNA-associated protein 21; U three protein 21; U3 snoRNA-associated protein 21", "protein_names_refseq": "rRNA-processing protein UTP21", "tax_id": 559292, "disease": "primary open angle glaucoma (Disease Ontology:DOID:1070); glaucoma (Disease Ontology:DOID:1686)", "pathway": " (sce:YLR409C); (R-SCE-6791226)", "pathway_count": 2, "publication_count": 12, "publication_id_list": "14562095;14562106;15590835;18407956;19795423;19823750;21126336;22814378;24374639;24466140;33491328;9169871", "class_list": "", "function": "Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VZ43", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0034388 Pwp2p-containing subcomplex of 90S preribosome;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0030686 90S preribosome", "go_biological_process": "GO:0006364 rRNA processing;GO:0030490 maturation of SSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q06078-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06135-1", "uniprot_id": "GAS2_YEAST", "mass": 62362.0, "length": 555, "protein_name": "1,3-beta-glucanosyltransferase GAS2", "gene_name": "GAS2", "organism": "Yeast", "refseq_name": "1,3-beta-glucanosyltransferase", "refseq_ac": "NP_013447", "gene_names_uniprotkb": "GAS2; L8300.5", "gene_names_refseq": "GAS2", "protein_names_uniprotkb": "1,3-beta-glucanosyltransferase GAS2; 2.4.1.-; Glycolipid-anchored surface protein 2", "protein_names_refseq": "1,3-beta-glucanosyltransferase", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR343W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "17189486;17397106;18468997;19097997;19779198;24374639;33491328;9169871", "class_list": "", "function": "Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall. Involved in spore wall assembly., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 12, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VYY2", "ec_number_list": "", "go_molecular_function": "GO:0042124 1,3-beta-glucanosyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0000324 fungal-type vacuole;GO:0009277 fungal-type cell wall;GO:0098552 side of membrane", "go_biological_process": "GO:0030476 ascospore wall assembly;GO:0031505 fungal-type cell wall organization;GO:0070880 fungal-type cell wall beta-glucan biosynthetic process;GO:0071970 fungal-type cell wall (1->3)-beta-D-glucan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q06135-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06142-1", "uniprot_id": "IMB1_YEAST", "mass": 94776.0, "length": 861, "protein_name": "Importin subunit beta-1", "gene_name": "KAP95", "organism": "Yeast", "refseq_name": "karyopherin beta", "refseq_ac": "NP_013451", "gene_names_uniprotkb": "KAP95; L8300.15", "gene_names_refseq": "KAP95; RSL1", "protein_names_uniprotkb": "Importin subunit beta-1; Importin-95; Karyopherin subunit beta-1; Karyopherin-95", "protein_names_refseq": "karyopherin beta", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR347C); (R-SCE-2995383); (R-SCE-6798695)", "pathway_count": 3, "publication_count": 20, "publication_id_list": "10684247;11309407;11423015;14562106;14648200;15864302;15878174;18407956;18708071;20826343;22814378;23749301;24374639;33481703;33491328;7622450;8521485;8621381;9169871;9321403", "class_list": "", "function": "Importin beta subunit that functions in nuclear protein import through association with the importin alpha subunit, which binds to the classical nuclear localization signal (cNLS) in cargo substrates (PubMed:7622450). Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by importin beta through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism (PubMed:8521485). At the nucleoplasmic side of the NPC, GTP-Ran binds to importin beta and the three components separate, leading to release of the cargo (PubMed:15864302). Importin alpha and beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin beta. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (PubMed:11423015). Mediates the nuclear import of histones H2A and H2B (PubMed:11309407). Mediates the nuclear import of transcription factor GCN4 (PubMed:14648200)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VYY6", "ec_number_list": "", "go_molecular_function": "GO:0061676 importin-alpha family protein binding;GO:0044877 protein-containing complex binding;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0031267 small GTPase binding;GO:0097718 disordered domain specific binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005643 nuclear pore;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0046822 regulation of nucleocytoplasmic transport;GO:0006612 protein targeting to membrane;GO:0051170 import into nucleus;GO:0006656 phosphatidylcholine biosynthetic process;GO:0051292 nuclear pore complex assembly", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "Q06142-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06144-1", "uniprot_id": "ORM2_YEAST", "mass": 24855.0, "length": 216, "protein_name": "Protein ORM2", "gene_name": "ORM2", "organism": "Yeast", "refseq_name": "sphingolipid homeostasis protein ORM2", "refseq_ac": "NP_013454", "gene_names_uniprotkb": "ORM2", "gene_names_refseq": "ORM2", "protein_names_uniprotkb": "Protein ORM2", "protein_names_refseq": "sphingolipid homeostasis protein ORM2", "tax_id": 559292, "disease": "Loeys-Dietz syndrome (Disease Ontology:DOID:0050466); childhood-onset asthma (Disease Ontology:DOID:0080815); asthma (Disease Ontology:DOID:2841); allergic asthma (Disease Ontology:DOID:9415)", "pathway": " (sce:YLR350W); (R-SCE-6798695)", "pathway_count": 2, "publication_count": 28, "publication_id_list": "12093374;14562095;14562106;16847258;17322287;17330950;17563356;18407956;19779198;19795423;19823750;20182505;21126336;22080611;23363605;23749301;24374639;27821475;31208443;31368600;31851579;32597660;32611771;33481703;33491328;34965436;39490931;9169871", "class_list": "", "function": "Component of the SPOTS complex that acts as a negative regulator of sphingolipid synthesis (PubMed:39490931). Acts by inhibiting serine palmitoyltransferases (LCB1 and LCB2) activity (PubMed:20182505). Along with ORM1, plays a role in the phosphorylation of LAC1 and YPK1, the distribution of actin patches between mother and daughter cells, and in endocytosis (PubMed:39490931)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYY8", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding", "go_cellular_component": "GO:0017059 serine palmitoyltransferase complex;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006897 endocytosis;GO:0030148 sphingolipid biosynthetic process;GO:0006672 ceramide metabolic process;GO:0090155 negative regulation of sphingolipid biosynthetic process;GO:0006986 response to unfolded protein", "synthesized_glycan_count": 0, "hit_score": 2.9, "record_id": "Q06144-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06163-1", "uniprot_id": "TERT_YEAST", "mass": 102635.0, "length": 884, "protein_name": "Telomerase reverse transcriptase", "gene_name": "EST2", "organism": "Yeast", "refseq_name": "telomerase reverse transcriptase", "refseq_ac": "NP_013422", "gene_names_uniprotkb": "EST2; L8543.12", "gene_names_refseq": "EST2", "protein_names_uniprotkb": "Telomerase reverse transcriptase; 2.7.7.49; Telomerase catalytic subunit", "protein_names_refseq": "telomerase reverse transcriptase", "tax_id": 559292, "disease": "idiopathic pulmonary fibrosis (Disease Ontology:DOID:0050156); small cell carcinoma (Disease Ontology:DOID:0050685); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); myelodysplastic syndrome (Disease Ontology:DOID:0050908); ductal carcinoma in situ (Disease Ontology:DOID:0060074); autosomal dominant dyskeratosis congenita 2 (Disease Ontology:DOID:0070016); prostate cancer (Disease Ontology:DOID:10283); silicosis (Disease Ontology:DOID:10325); stomach cancer (Disease Ontology:DOID:10534); urinary bladder cancer (Disease Ontology:DOID:11054); beta thalassemia (Disease Ontology:DOID:12241); aplastic anemia (Disease Ontology:DOID:12449); brain cancer (Disease Ontology:DOID:1319); lung cancer (Disease Ontology:DOID:1324); cancer (Disease Ontology:DOID:162); hepatitis C (Disease Ontology:DOID:1883); viral hepatitis (Disease Ontology:DOID:1884); melanoma (Disease Ontology:DOID:1909); leiomyosarcoma (Disease Ontology:DOID:1967); nephroblastoma (Disease Ontology:DOID:2154); transient cerebral ischemia (Disease Ontology:DOID:224); transitional cell carcinoma (Disease Ontology:DOID:2671); teratoma (Disease Ontology:DOID:3307); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung squamous cell carcinoma (Disease Ontology:DOID:3907); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); renal cell carcinoma (Disease Ontology:DOID:4450); gallbladder carcinoma (Disease Ontology:DOID:4948); hepatocellular clear cell carcinoma (Disease Ontology:DOID:5016); pulmonary hypertension (Disease Ontology:DOID:6432); hepatocellular carcinoma (Disease Ontology:DOID:684); familial melanoma (Disease Ontology:DOID:6846); chronic kidney disease (Disease Ontology:DOID:784); chronic myeloid leukemia (Disease Ontology:DOID:8552); cervix uteri carcinoma in situ (Disease Ontology:DOID:8991); acute myeloid leukemia (Disease Ontology:DOID:9119); gastrointestinal stromal tumor (Disease Ontology:DOID:9253); nasopharynx carcinoma (Disease Ontology:DOID:9261); plasma cell leukemia (Disease Ontology:DOID:9513); multiple myeloma (Disease Ontology:DOID:9538); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (sce:YLR318W)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "17563356;20702584;24374639;33481703;33491328;9110970;9169871", "class_list": "", "function": "Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 42, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYW1", "ec_number_list": "2.7.7.7;3.1.26.4;2.7.7.49;3.4.23.-;3.1.11.-", "go_molecular_function": "GO:0046872 metal ion binding;GO:0042162 telomeric DNA binding;GO:0003720 telomerase activity;GO:0070034 telomerase RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005697 telomerase holoenzyme complex;GO:0000781 chromosome, telomeric region;GO:0000333 telomerase catalytic core complex", "go_biological_process": "GO:0007004 telomere maintenance via telomerase", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q06163-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06213-1", "uniprot_id": "MED10_YEAST", "mass": 17908.0, "length": 157, "protein_name": "Mediator of RNA polymerase II transcription subunit 10", "gene_name": "NUT2", "organism": "Yeast", "refseq_name": "mediator complex subunit NUT2", "refseq_ac": "NP_015494", "gene_names_uniprotkb": "NUT2; MED10; P9325.2", "gene_names_refseq": "MED10; NUT2", "protein_names_uniprotkb": "Mediator of RNA polymerase II transcription subunit 10; Mediator complex subunit 10; Negative regulator of URS2 protein 2", "protein_names_refseq": "mediator complex subunit NUT2", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR168W)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "11555651;12191485;14562095;14562106;15175151;15477388;15710619;16002404;16076843;16263706;17192271;23749301;24374639;33481703;33491328;9169875;9671481;9812975", "class_list": "", "function": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. The Mediator complex unfolds to an extended conformation and partially surrounds RNA polymerase II, specifically interacting with the unphosphorylated form of the C-terminal domain (CTD) of RNA polymerase II. The Mediator complex dissociates from the RNA polymerase II holoenzyme and stays at the promoter when transcriptional elongation begins., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W4G9", "ec_number_list": "", "go_molecular_function": "GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016592 mediator complex;GO:0070847 core mediator complex", "go_biological_process": "GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0032968 positive regulation of transcription elongation by RNA polymerase II;GO:0051123 RNA polymerase II preinitiation complex assembly", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "Q06213-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06245-1", "uniprot_id": "SEC10_YEAST", "mass": 100342.0, "length": 871, "protein_name": "Exocyst complex component SEC10", "gene_name": "SEC10", "organism": "Yeast", "refseq_name": "exocyst subunit SEC10", "refseq_ac": "NP_013267", "gene_names_uniprotkb": "SEC10; L9362.12", "gene_names_refseq": "SEC10", "protein_names_uniprotkb": "Exocyst complex component SEC10", "protein_names_refseq": "exocyst subunit SEC10", "tax_id": 559292, "disease": "obstructive nephropathy (Disease Ontology:DOID:0070314); bicuspid aortic valve disease (Disease Ontology:DOID:0080332)", "pathway": " (sce:YLR166C); (R-SCE-264876)", "pathway_count": 2, "publication_count": 14, "publication_id_list": "14562106;15665377;17330950;18407956;19779198;21126336;22218487;23749301;24374639;32597660;33481703;33491328;8978675;9169871", "class_list": "", "function": "Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYH2;P87329", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000145 exocyst;GO:0005935 cellular bud neck;GO:0043332 mating projection tip", "go_biological_process": "GO:0015031 protein transport;GO:0006887 exocytosis;GO:0006893 Golgi to plasma membrane transport;GO:0006904 vesicle docking involved in exocytosis", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q06245-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06344-1", "uniprot_id": "ESF1_YEAST", "mass": 72410.0, "length": 628, "protein_name": "Pre-rRNA-processing protein ESF1", "gene_name": "ESF1", "organism": "Yeast", "refseq_name": "pre-rRNA-processing protein ESF1", "refseq_ac": "NP_010653", "gene_names_uniprotkb": "ESF1", "gene_names_refseq": "ESF1", "protein_names_uniprotkb": "Pre-rRNA-processing protein ESF1; 18S rRNA factor 1", "protein_names_refseq": "pre-rRNA-processing protein ESF1", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR365C)", "pathway_count": 1, "publication_count": 24, "publication_id_list": "14562095;14562106;14690591;15056729;17287358;17330950;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;21725298;22218487;22814378;23749301;24374639;30516470;32597660;33481703;33491328;9169867", "class_list": "", "function": "Involved in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 17, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSZ4", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus", "go_biological_process": "GO:0006364 rRNA processing", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "Q06344-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06505-1", "uniprot_id": "IWS1_YEAST", "mass": 46082.0, "length": 410, "protein_name": "Transcription factor SPN1", "gene_name": "SPN1", "organism": "Yeast", "refseq_name": "transcription factor SPN1", "refseq_ac": "NP_015458", "gene_names_uniprotkb": "SPN1; IWS1", "gene_names_refseq": "IWS1; SPN1", "protein_names_uniprotkb": "Transcription factor SPN1; Interacts with SPT6 protein 1; Suppresses postrecruitment functions protein 1", "protein_names_refseq": "transcription factor SPN1", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR133C)", "pathway_count": 1, "publication_count": 27, "publication_id_list": "12242279;12524336;12556496;14562095;14562106;17287358;17322287;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20190278;20702584;21126336;21177495;22218487;23749301;24374639;30516470;32597660;33229814;33481703;33491328;9169875", "class_list": "", "function": "Transcription factor involved in RNA polymerase II transcription regulation. May function in both SPT15/TBP post-recruitment and recruitment steps of transcription., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 24, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D6W4C9", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0000993 RNA polymerase II complex binding;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005665 RNA polymerase II, core complex", "go_biological_process": "GO:0016973 poly(A)+ mRNA export from nucleus;GO:0034243 regulation of transcription elongation by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006334 nucleosome assembly", "synthesized_glycan_count": 0, "hit_score": 3.2, "record_id": "Q06505-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06604-1", "uniprot_id": "BSP1_YEAST", "mass": 64666.0, "length": 576, "protein_name": "F-actin capping regulator BSP1", "gene_name": "BSP1", "organism": "Yeast", "refseq_name": "Bsp1p", "refseq_ac": "NP_015497", "gene_names_uniprotkb": "BSP1", "gene_names_refseq": "BSP1", "protein_names_uniprotkb": "F-actin capping regulator BSP1; Binding of synaptojanin polyphosphoinositide phosphatase domain protein 1; CPI motif-containing protein BSP1; Capping protein interaction motif-containing protein BSP1", "protein_names_refseq": "Bsp1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR171W)", "pathway_count": 1, "publication_count": 27, "publication_id_list": "11489916;12606027;14562095;14562106;14574415;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22218487;23749301;24374639;24909858;30516470;32597660;33229814;33481703;33491328;38088874;9169875", "class_list": "", "function": "Recruits the capping protein complex to actin patches and the actomyosin contractile ring, and/or stabilizes their interaction (PubMed:12606027, PubMed:38088874). May serve as an adapter to link INP52 and INP53 to the cortical actin cytoskeleton (PubMed:12606027). Binds F-actin (PubMed:38088874)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 8, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 8, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 8, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 43, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "D6W4H2", "ec_number_list": "", "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030479 actin cortical patch;GO:0005934 cellular bud tip;GO:0005935 cellular bud neck", "go_biological_process": "GO:0051666 actin cortical patch localization;GO:1904498 protein localization to mitotic actomyosin contractile ring;GO:0044379 protein localization to actin cortical patch", "synthesized_glycan_count": 0, "hit_score": 3.7, "record_id": "Q06604-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06631-1", "uniprot_id": "BFR2_YEAST", "mass": 61203.0, "length": 534, "protein_name": "Protein BFR2", "gene_name": "BFR2", "organism": "Yeast", "refseq_name": "rRNA-processing protein BFR2", "refseq_ac": "NP_010585", "gene_names_uniprotkb": "BFR2", "gene_names_refseq": "BFR2", "protein_names_uniprotkb": "Protein BFR2; Brefeldin A resistance protein 2", "protein_names_refseq": "rRNA-processing protein BFR2", "tax_id": 559292, "disease": "chromosome 17q12 deletion syndrome (Disease Ontology:DOID:0060404)", "pathway": " (sce:YDR299W)", "pathway_count": 1, "publication_count": 26, "publication_id_list": "11875433;14562095;14562106;14690591;17322287;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21126336;21177495;22218487;23749301;24374639;24909858;30516470;32597660;33481703;33491328;9169867;9472076;9645427", "class_list": "", "function": "Involved in endoplasmic reticulum to Golgi transport. Involved in a protein-transport step blocked by brefeldin A, which disrupts the Golgi apparatus and its incoming protein flux. May also be involved for mass growth or cell proliferation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 17, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSS8;Q66RD8", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005730 nucleolus;GO:0030686 90S preribosome;GO:0032040 small-subunit processome", "go_biological_process": "GO:0015031 protein transport;GO:0016192 vesicle-mediated transport;GO:0006364 rRNA processing;GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 2.7, "record_id": "Q06631-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06682-1", "uniprot_id": "UBX5_YEAST", "mass": 56737.0, "length": 500, "protein_name": "UBX domain-containing protein 5", "gene_name": "UBX5", "organism": "Yeast", "refseq_name": "DNA protein crosslink repair co-factor UBX5", "refseq_ac": "NP_010617", "gene_names_uniprotkb": "UBX5", "gene_names_refseq": "UBX5", "protein_names_uniprotkb": "UBX domain-containing protein 5", "protein_names_refseq": "DNA protein crosslink repair co-factor UBX5", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR330W); (R-SCE-8951664); (R-SCE-9755511)", "pathway_count": 3, "publication_count": 13, "publication_id_list": "14562095;14562106;15258615;17330950;18407956;19684113;19779198;22218487;23749301;24374639;33481703;33491328;9169867", "class_list": "", "function": "Involved in CDC48-dependent protein degradation through the ubiquitin/proteasome pathway., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VSW2", "ec_number_list": "", "go_molecular_function": "GO:0051117 ATPase binding;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q06682-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07468-1", "uniprot_id": "VAM6_YEAST", "mass": 122882.0, "length": 1049, "protein_name": "Vacuolar morphogenesis protein 6", "gene_name": "VAM6", "organism": "Yeast", "refseq_name": "Vam6p", "refseq_ac": "NP_010206", "gene_names_uniprotkb": "VAM6; CVT4; VPL18; VPL22; VPS39", "gene_names_refseq": "CVT4; VAM6; VPL18; VPL22; VPS39", "protein_names_uniprotkb": "Vacuolar morphogenesis protein 6; Vacuolar protein sorting-associated protein 39", "protein_names_refseq": "Vam6p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL077C)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "14562106;16601699;19779198;23749301;24374639;32597660;32801125;33481703;33491328;9111041;9169867", "class_list": "", "function": "Required for vacuolar assembly. Acts as a component of the HOPS complex that acts during the docking stage of vacuole fusion. HOPS is an effector for the vacuolar Rab GTPase YPT7 and is required for vacuolar SNARE complex assembly. It remains bound to SNARE complexes after vacuole fusion., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRS2", "ec_number_list": "", "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0030897 HOPS complex;GO:0005737 cytoplasm;GO:0000329 fungal-type vacuole membrane;GO:0000324 fungal-type vacuole;GO:1990816 vacuole-mitochondrion membrane contact site", "go_biological_process": "GO:0097352 autophagosome maturation;GO:1904263 positive regulation of TORC1 signaling;GO:0097576 vacuole fusion;GO:0035542 regulation of SNARE complex assembly;GO:0042144 vacuole fusion, non-autophagic", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q07468-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07794-1", "uniprot_id": "RT109_YEAST", "mass": 50096.0, "length": 436, "protein_name": "Histone acetyltransferase RTT109", "gene_name": "RTT109", "organism": "Yeast", "refseq_name": "H3 histone acetyltransferase RTT109", "refseq_ac": "NP_013099", "gene_names_uniprotkb": "RTT109; KAT11; KIM2; L1377; REM50", "gene_names_refseq": "KAT11; KIM2; REM50; RTT109", "protein_names_uniprotkb": "Histone acetyltransferase RTT109; 2.3.1.48; Regulator of Ty1 transposition protein 109", "protein_names_refseq": "H3 histone acetyltransferase RTT109", "tax_id": 559292, "disease": "", "pathway": " (sce:YLL002W)", "pathway_count": 1, "publication_count": 27, "publication_id_list": "11779788;14562095;14562106;15282802;17046836;17272722;17272723;17320445;17369253;17690098;18568037;18577595;18707894;18719104;18723682;19172748;19683497;20560668;21256037;21454705;24374639;26468616;29300933;31194870;31387991;8810043;9169871", "class_list": "", "function": "Histone chaperone-dependent acetylase that modifies 'Lys-9', 'Lys-14', 'Lys-23', 'Lys-27', and 'Lys-56' on histone H3 (H3K9Ac, H3K14Ac and H3K23Ac, H3K27Ac, and H3K56Ac) to promote nucleosome assembly, genomic stability, DNA repair and transcriptional regulation during mitotic S-phase (PubMed:17046836, PubMed:17272723, PubMed:17320445, PubMed:17369253, PubMed:18723682, PubMed:19172748, PubMed:19683497, PubMed:20560668, PubMed:21256037, PubMed:29300933, PubMed:31194870). Its residue selectivity is influenced by the acetylation status of histone H3, and also the presence of histone chaperone ASF1 that shifts selectivity to 'Lys-56' when H3K14Ac is already present (PubMed:31194870). H3K56 acetylation weakens the interaction between the histone core and the surrounding DNA in the nucleosomal particle and drives chromatin disassembly (PubMed:18577595). Autoacetylates (PubMed:18568037, PubMed:18707894, PubMed:18719104). Independently of acetyltransferase activity, stimulates histone deposition by VPS75 (PubMed:19172748). Involved in regulation of Ty1 transposition (PubMed:11779788)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 33, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "D6VY01", "ec_number_list": "2.3.1.48;2.3.1.-", "go_molecular_function": "GO:0061733 protein-lysine-acetyltransferase activity;GO:0010484 histone H3 acetyltransferase activity;GO:0043994 histone H3K23 acetyltransferase activity;GO:0036408 histone H3K14 acetyltransferase activity;GO:0044017 histone H3K27 acetyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0070775 H3 histone acetyltransferase complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006974 DNA damage response;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 2.8, "record_id": "Q07794-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07896-1", "uniprot_id": "NOC3_YEAST", "mass": 75582.0, "length": 663, "protein_name": "Nucleolar complex-associated protein 3", "gene_name": "NOC3", "organism": "Yeast", "refseq_name": "Noc3p", "refseq_ac": "NP_013102", "gene_names_uniprotkb": "NOC3", "gene_names_refseq": "NOC3", "protein_names_uniprotkb": "Nucleolar complex-associated protein 3", "protein_names_refseq": "Noc3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YLR002C)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "11371346;11583615;12110182;14562106;18407956;19779198;20702584;21126336;24374639;30516470;32597660;33481703;33491328;8810043;9169871", "class_list": "", "function": "Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Also required for initiation of DNA replication. May function downstream of the origin recognition complex (ORC complex) in the loading of CDC6 and the minichromosome maintenance complex (MCM complex) onto chromatin during the G1 phase of the cell cycle. Essential for growth., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VY04;Q92280", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding", "go_cellular_component": "GO:0005656 nuclear pre-replicative complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0030691 Noc2p-Noc3p complex", "go_biological_process": "GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication;GO:0051301 cell division;GO:0042273 ribosomal large subunit biogenesis;GO:0006364 rRNA processing;GO:0006270 DNA replication initiation", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q07896-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08032-1", "uniprot_id": "CDC45_YEAST", "mass": 74249.0, "length": 650, "protein_name": "Cell division control protein 45", "gene_name": "CDC45", "organism": "Yeast", "refseq_name": "DNA replication initiation factor CDC45", "refseq_ac": "NP_013204", "gene_names_uniprotkb": "CDC45; L8004.11; SLD4", "gene_names_refseq": "CDC45; SLD4", "protein_names_uniprotkb": "Cell division control protein 45", "protein_names_refseq": "DNA replication initiation factor CDC45", "tax_id": 559292, "disease": "Meier-Gorlin syndrome (Disease Ontology:DOID:0060306); chromosome 22q11.2 deletion syndrome, distal (Disease Ontology:DOID:0060413); Meier-Gorlin syndrome 7 (Disease Ontology:DOID:0080518)", "pathway": " (sce:YLR103C); (R-SCE-176187); (R-SCE-68962)", "pathway_count": 3, "publication_count": 14, "publication_id_list": "14562106;15201046;18407956;20702584;21126336;23749301;24374639;30595439;32597660;33481703;33491328;8901577;9001208;9169871", "class_list": "", "function": "Required for initiation of chromosomal DNA replication. Acts at the origin of replication. Also has a role in minichromosome maintenance., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYA3;Q05908", "ec_number_list": "", "go_molecular_function": "GO:0003688 DNA replication origin binding;GO:0003682 chromatin binding;GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0031261 DNA replication preinitiation complex;GO:0043596 nuclear replication fork;GO:0005634 nucleus;GO:0071162 CMG complex", "go_biological_process": "GO:1902977 mitotic DNA replication preinitiation complex assembly;GO:0006260 DNA replication;GO:0006270 DNA replication initiation;GO:0000727 double-strand break repair via break-induced replication", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q08032-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08438-1", "uniprot_id": "VHS3_YEAST", "mass": 73649.0, "length": 674, "protein_name": "Phosphopantothenoylcysteine decarboxylase subunit VHS3", "gene_name": "VHS3", "organism": "Yeast", "refseq_name": "phosphopantothenoylcysteine decarboxylase complex subunit VHS3", "refseq_ac": "NP_014697", "gene_names_uniprotkb": "VHS3; YOR29-05", "gene_names_refseq": "VHS3; YOR29-05", "protein_names_uniprotkb": "Phosphopantothenoylcysteine decarboxylase subunit VHS3; Viable in a HAL3 SIT4 background protein 3", "protein_names_refseq": "phosphopantothenoylcysteine decarboxylase complex subunit VHS3", "tax_id": 559292, "disease": "neurodegeneration with brain iron accumulation (Disease Ontology:DOID:0110734); dilated cardiomyopathy (Disease Ontology:DOID:12930)", "pathway": " (sce:YOR054C)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "12518319;14690591;15192104;15665377;17330950;17563356;18407956;19779198;19915539;20702584;21177495;22814378;23749301;24374639;32597660;33481703;33491328;9133743;9169874", "class_list": "", "function": "Component of the phosphopantothenoylcysteine decarboxylase (PPCDC) involved in the coenzyme A synthesis. Acts as an inhibitory subunit of protein phosphatase PPZ1, which is involved in many cellular processes such as G1-S transition or salt tolerance., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 23, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2B8;O00019", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0003824 catalytic activity;GO:0004864 protein phosphatase inhibitor activity;GO:0010181 FMN binding", "go_cellular_component": "GO:0071513 phosphopantothenoylcysteine decarboxylase complex;GO:1990143 CoA-synthesizing protein complex", "go_biological_process": "GO:0015937 coenzyme A biosynthetic process;GO:0030003 intracellular monoatomic cation homeostasis", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "Q08438-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08496-1", "uniprot_id": "DIA2_YEAST", "mass": 85070.0, "length": 732, "protein_name": "Protein DIA2", "gene_name": "DIA2", "organism": "Yeast", "refseq_name": "DNA-binding SCF ubiquitin ligase subunit DIA2", "refseq_ac": "NP_014723", "gene_names_uniprotkb": "DIA2; YOR29-31", "gene_names_refseq": "DIA2; YOR29-31", "protein_names_uniprotkb": "Protein DIA2; Digs into agar protein 2", "protein_names_refseq": "DNA-binding SCF ubiquitin ligase subunit DIA2", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR080W)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10582239;11063681;14747994;14993228;15579722;15620357;16421250;16487579;18407956;19913425;24374639;33491328;9133743;9169874", "class_list": "", "function": "F-box protein component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins (By similarity). The SCF(DIA2) complex is specifically involved in the pheromone induced degradation of phosphorylated TEC1. The SCF(DIA2) complex binds to DNA replication origins. Involved in DNA replication, genome stability, and the control of cell cycle, probably through its association to replication origins to facilitate the ubiquitination of another origin-binding protein. Required for invasive growth and growth under alkaline conditions., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2E3;O00034;Q7LGN4", "ec_number_list": "", "go_molecular_function": "GO:0003688 DNA replication origin binding", "go_cellular_component": "GO:0043596 nuclear replication fork;GO:0005634 nucleus;GO:0019005 SCF ubiquitin ligase complex;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0031509 subtelomeric heterochromatin formation;GO:0016567 protein ubiquitination;GO:0006275 regulation of DNA replication;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0031573 mitotic intra-S DNA damage checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q08496-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08873-1", "uniprot_id": "SCP1_YEAST", "mass": 22748.0, "length": 200, "protein_name": "Transgelin", "gene_name": "SCP1", "organism": "Yeast", "refseq_name": "Scp1p", "refseq_ac": "NP_015012", "gene_names_uniprotkb": "SCP1", "gene_names_refseq": "SCP1", "protein_names_uniprotkb": "Transgelin; Calponin homolog 1", "protein_names_refseq": "Scp1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR367W); (R-SCE-114608); (R-SCE-6798695)", "pathway_count": 3, "publication_count": 18, "publication_id_list": "12857851;12868959;14562095;14562106;14737190;17287358;17330950;18400761;18407956;19779198;20702584;22814378;23749301;24374639;30516470;33481703;33491328;9169874", "class_list": "", "function": "Has actin-binding and actin-bundling activity. Stabilizes actin filaments against disassembly., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W360", "ec_number_list": "", "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0051015 actin filament binding", "go_cellular_component": "GO:0015629 actin cytoskeleton;GO:0030479 actin cortical patch", "go_biological_process": "GO:0007015 actin filament organization", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "Q08873-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08921-1", "uniprot_id": "TCO89_YEAST", "mass": 88845.0, "length": 799, "protein_name": "Target of rapamycin complex 1 subunit TCO89", "gene_name": "TCO89", "organism": "Yeast", "refseq_name": "Tco89p", "refseq_ac": "NP_015145", "gene_names_uniprotkb": "TCO89", "gene_names_refseq": "TCO89", "protein_names_uniprotkb": "Target of rapamycin complex 1 subunit TCO89; 89 kDa TOR complex 1 protein; TORC1 subunit TCO89", "protein_names_refseq": "Tco89p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL180W)", "pathway_count": 1, "publication_count": 29, "publication_id_list": "14562095;14562106;14736892;15665377;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20489023;20702584;21126336;21177495;22218487;23749301;24374639;24909858;29698392;30516470;32597660;32801125;33229814;33481703;33491328;34965436;9169875", "class_list": "", "function": "Component of TORC1, which regulates multiple cellular processes to control cell growth in response to environmental signals. Nutrient limitation and environmental stress signals cause inactivation of TORC1. Active TORC1 positively controls ribosome biogenesis via control of rRNA, ribosomal protein and tRNA gene expression, and rRNA processing. TORC1 positively controls protein biosynthesis by regulation of mRNA stability, translation initiation factor activity, and high-affinity amino acid permeases that serve to provide amino acids for use by the translation machinery. TORC1 also promotes growth by sequestering a number of nutrient and general stress-responsive transcription factors in the cytoplasm. TORC1 negatively controls macroautophagy, a process to recycle surplus cytoplasmic mass under nutrient starvation conditions., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 87, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6W3I8", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0031931 TORC1 complex;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0007584 response to nutrient;GO:0001558 regulation of cell growth;GO:0031929 TOR signaling;GO:0009651 response to salt stress;GO:0006071 glycerol metabolic process", "synthesized_glycan_count": 0, "hit_score": 3.3, "record_id": "Q08921-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08962-1", "uniprot_id": "NIP7_YEAST", "mass": 20381.0, "length": 181, "protein_name": "60S ribosome subunit biogenesis protein NIP7", "gene_name": "NIP7", "organism": "Yeast", "refseq_name": "ribosome biosynthesis protein NIP7", "refseq_ac": "NP_015113", "gene_names_uniprotkb": "NIP7", "gene_names_refseq": "NIP7", "protein_names_uniprotkb": "60S ribosome subunit biogenesis protein NIP7; Nuclear import protein 7", "protein_names_refseq": "ribosome biosynthesis protein NIP7", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL211W)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "11583615;14562106;17322287;18001138;19779198;24374639;9169875;9271378;9891085", "class_list": "", "function": "Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3F9", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0030687 preribosome, large subunit precursor", "go_biological_process": "GO:0042273 ribosomal large subunit biogenesis;GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:1902626 assembly of large subunit precursor of preribosome", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q08962-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08966-1", "uniprot_id": "PCL8_YEAST", "mass": 55431.0, "length": 492, "protein_name": "PHO85 cyclin-8", "gene_name": "PCL8", "organism": "Yeast", "refseq_name": "Pcl8p", "refseq_ac": "NP_015105", "gene_names_uniprotkb": "PCL8; P1745", "gene_names_refseq": "PCL8", "protein_names_uniprotkb": "PHO85 cyclin-8", "protein_names_refseq": "Pcl8p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL219W)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "12407105;14562106;17322287;19779198;20489023;23749301;24374639;32597660;33481703;33491328;9032248;9169875;9584169", "class_list": "", "function": "Cyclin partner of the cyclin-dependent kinase (CDK) PHO85. Together with cyclin PCL10, negatively controls glycogen accumulation under favorable growth conditions. Involved in phosphorylation and negative regulation of glycogen synthase GSY2. Also has minor GLC8 kinase activity., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3F1;Q6B153", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding;GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000307 cyclin-dependent protein kinase holoenzyme complex", "go_biological_process": "GO:0005977 glycogen metabolic process;GO:0005979 regulation of glycogen biosynthetic process;GO:0045719 negative regulation of glycogen biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q08966-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12045-1", "uniprot_id": "VIK1_YEAST", "mass": 75730.0, "length": 647, "protein_name": "Spindle pole body-associated protein VIK1", "gene_name": "VIK1", "organism": "Yeast", "refseq_name": "Vik1p", "refseq_ac": "NP_015070", "gene_names_uniprotkb": "VIK1", "gene_names_refseq": "VIK1", "protein_names_uniprotkb": "Spindle pole body-associated protein VIK1; Vegetative interaction with KAR3 protein 1", "protein_names_refseq": "Vik1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL253C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10087265;11729143;17382884;22734002;24374639;25313961;33491328;9169875", "class_list": "", "function": "Together with the minus end-directed microtubule motor KAR3, plays a role in microtubule organization (PubMed:17382884, PubMed:22734002, PubMed:25313961). Recruits KAR3 to microtubules, and together they may stabilize the polymers (PubMed:17382884, PubMed:25313961). The KAR3-VIK1 heterodimer cross-links anti-parallel microtubules (PubMed:17382884, PubMed:22734002). Targets and/or maintains KAR3 at the spindle pole body during vegetative growth (PubMed:10087265, PubMed:11729143)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3B8;Q7LGU6", "ec_number_list": "", "go_molecular_function": "GO:0008017 microtubule binding;GO:0008093 cytoskeletal anchor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005871 kinesin complex;GO:0005816 spindle pole body", "go_biological_process": "GO:0007020 microtubule nucleation;GO:0036503 ERAD pathway;GO:0007064 mitotic sister chromatid cohesion;GO:0007017 microtubule-based process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q12045-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12050-1", "uniprot_id": "ELG1_YEAST", "mass": 91262.0, "length": 791, "protein_name": "Telomere length regulation protein ELG1", "gene_name": "ELG1", "organism": "Yeast", "refseq_name": "Elg1p", "refseq_ac": "NP_014787", "gene_names_uniprotkb": "ELG1; O3510; RTT110; YOR3510C", "gene_names_refseq": "ELG1; RTT110", "protein_names_uniprotkb": "Telomere length regulation protein ELG1; Regulator of Ty1 transposition protein 110; Telomere elongation suppressor ELG1", "protein_names_refseq": "Elg1p", "tax_id": 559292, "disease": "neurilemmoma (Disease Ontology:DOID:3192)", "pathway": " (sce:YOR144C)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "12909721;12912927;13678589;14562095;14745004;15964801;17287358;18407956;19779198;23749301;24374639;26177013;31186330;32597660;33481703;33491328;9046089;9169874;9200815", "class_list": "", "function": "Involved in the negative control of telomere length and in telomeric silencing through a replication-mediated pathway. May have a role in Okazaki fragment maturation. Required for S-phase progression. Component of the RFC-like ELG1-RFC complex which appears to have a role in DNA replication, replication fork re-start, recombination and repair., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2K2;O94148;Q03129;Q7LI57", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0031391 Elg1 RFC-like complex;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0006260 DNA replication;GO:0000724 double-strand break repair via homologous recombination;GO:0007064 mitotic sister chromatid cohesion;GO:0031507 heterochromatin formation;GO:0006261 DNA-templated DNA replication", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "Q12050-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12080-1", "uniprot_id": "NOP53_YEAST", "mass": 52556.0, "length": 455, "protein_name": "Ribosome biogenesis protein NOP53", "gene_name": "NOP53", "organism": "Yeast", "refseq_name": "Nop53p", "refseq_ac": "NP_015179", "gene_names_uniprotkb": "NOP53; LPI2C; P2610", "gene_names_refseq": "NOP53", "protein_names_uniprotkb": "Ribosome biogenesis protein NOP53; Nucleolar protein 53", "protein_names_refseq": "Nop53p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL146C)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "14562106;15686447;16043506;16128814;17563356;18407956;18631361;19684113;19779198;19795423;19823750;20702584;21177495;23749301;24374639;30516470;33481703;33491328;8948103;9169875", "class_list": "", "function": "Late-acting factor in the nuclear maturation of 60S ribosomal subunits, which is required for normal acquisition of export competence. Required for the export of the large subunit. Acts to stimulate the RNase activity of the exosome complex, and may recruit the exosome to 7S pre-rRNA for processing. Associates with numerous RNAs including the 27S and 7S pre-rRNAs and the box H/ACA snoRNA snR37. Also interacts (via N-terminal region) with the mature 25S rRNA and the mature 5.8S rRNA., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3M3", "ec_number_list": "", "go_molecular_function": "GO:0019843 rRNA binding;GO:0008097 5S rRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0000176 nuclear exosome (RNase complex)", "go_biological_process": "GO:0000055 ribosomal large subunit export from nucleus;GO:0006364 rRNA processing;GO:0000460 maturation of 5.8S rRNA;GO:0000027 ribosomal large subunit assembly;GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "Q12080-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12084-1", "uniprot_id": "DAS2_YEAST", "mass": 26595.0, "length": 232, "protein_name": "Putative uridine kinase DAS2", "gene_name": "DAS2", "organism": "Yeast", "refseq_name": "putative uridine kinase DAS2", "refseq_ac": "NP_010303", "gene_names_uniprotkb": "DAS2; PZE232; RRT3", "gene_names_refseq": "DAS2; RRT3", "protein_names_uniprotkb": "Putative uridine kinase DAS2; 2.7.1.48; DST1-delta 6-azauracil sensitivity protein 2; Regulator of rDNA transcription 3", "protein_names_refseq": "putative uridine kinase DAS2", "tax_id": 559292, "disease": "pancreatic cancer (Disease Ontology:DOID:1793); nerve compression syndrome (Disease Ontology:DOID:573)", "pathway": " (sce:YDR020C)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "14562095;14562106;17322287;19270272;19795423;19823750;24374639;33491328;8896275;9169867", "class_list": "", "function": "Putative uridine kinase identified in a screen for mutants with increased levels of rDNA transcription., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VS06", "ec_number_list": "2.7.1.48", "go_molecular_function": "GO:0005524 ATP binding;GO:0004849 uridine kinase activity;GO:0043771 cytidine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0044206 UMP salvage;GO:0044211 CTP salvage", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q12084-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12118-1", "uniprot_id": "SGT2_YEAST", "mass": 37218.0, "length": 346, "protein_name": "Small glutamine-rich tetratricopeptide repeat-containing protein 2", "gene_name": "SGT2", "organism": "Yeast", "refseq_name": "Sgt2p", "refseq_ac": "NP_014649", "gene_names_uniprotkb": "SGT2; UNF346", "gene_names_refseq": "SGT2", "protein_names_uniprotkb": "Small glutamine-rich tetratricopeptide repeat-containing protein 2; SGT/UBP; Viral protein U-binding protein", "protein_names_refseq": "Sgt2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR007C); (R-SCE-9609523)", "pathway_count": 2, "publication_count": 13, "publication_id_list": "12482202;14562095;14562106;17441508;18407956;19779198;21126336;23749301;24374639;33481703;33491328;8896276;9169874", "class_list": "", "function": "Co-chaperone that binds to the molecular chaperone Hsp70 (SSA1 and SSA2). Regulates Hsp70 ATPase activity (By similarity). Required for recovery from heat shock., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W273", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0042802 identical protein binding;GO:0031072 heat shock protein binding;GO:0051879 Hsp90 protein binding;GO:0030544 Hsp70 protein binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016020 membrane;GO:0072380 TRC complex", "go_biological_process": "GO:0006620 post-translational protein targeting to endoplasmic reticulum membrane;GO:0009408 response to heat", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q12118-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12125-1", "uniprot_id": "GET4_YEAST", "mass": 36280.0, "length": 312, "protein_name": "Golgi to ER traffic protein 4", "gene_name": "GET4", "organism": "Yeast", "refseq_name": "protein GET4", "refseq_ac": "NP_014807", "gene_names_uniprotkb": "GET4; O3580", "gene_names_refseq": "ENV8; GET4", "protein_names_uniprotkb": "Golgi to ER traffic protein 4; Guided entry of tail-anchored proteins 4", "protein_names_refseq": "protein GET4", "tax_id": 559292, "disease": "congenital disorder of glycosylation type IIy (Disease Ontology:DOID:0051052)", "pathway": " (sce:YOR164C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14562095;14562106;17322287;19325107;20106980;22814378;24374639;8972579;9169874", "class_list": "", "function": "May play a role in insertion of tail-anchored proteins into the endoplasmic reticulum membrane., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2M2", "ec_number_list": "", "go_molecular_function": "GO:0140597 protein carrier chaperone", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0072380 TRC complex", "go_biological_process": "GO:0006620 post-translational protein targeting to endoplasmic reticulum membrane;GO:0045048 protein insertion into ER membrane;GO:0016192 vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q12125-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12134-1", "uniprot_id": "HUA2_YEAST", "mass": 28414.0, "length": 243, "protein_name": "Protein HUA2", "gene_name": "HUA2", "organism": "Yeast", "refseq_name": "Hua2p", "refseq_ac": "NP_014927", "gene_names_uniprotkb": "HUA2", "gene_names_refseq": "HUA2", "protein_names_uniprotkb": "Protein HUA2", "protein_names_refseq": "Hua2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR284W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14562095;14562106;14566057;23749301;24374639;33481703;8896271;9169874", "class_list": "", "function": "May have a role in actin patch assembly., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2Y2", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q12134-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12220-1", "uniprot_id": "UTP12_YEAST", "mass": 106342.0, "length": 943, "protein_name": "U3 small nucleolar RNA-associated protein 12", "gene_name": "DIP2", "organism": "Yeast", "refseq_name": "snoRNA-binding rRNA-processing protein DIP2", "refseq_ac": "NP_013230", "gene_names_uniprotkb": "DIP2; L3116; L9233.1; UTP12", "gene_names_refseq": "DIP2; UTP12", "protein_names_uniprotkb": "U3 small nucleolar RNA-associated protein 12; DOM34-interacting protein 2; U three protein 12; U3 snoRNA-associated protein 12", "protein_names_refseq": "snoRNA-binding rRNA-processing protein DIP2", "tax_id": 559292, "disease": "papillary thyroid carcinoma (Disease Ontology:DOID:3969)", "pathway": " (sce:YLR129W); (R-SCE-6791226)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "12068309;14562106;19684113;19779198;23749301;24374639;33481703;33491328;9169871", "class_list": "", "function": "Involved in nucleolar processing of pre-18S ribosomal RNA., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYC4;Q05386", "ec_number_list": "", "go_molecular_function": "GO:0030515 snoRNA binding;GO:0034511 U3 snoRNA binding", "go_cellular_component": "GO:0034388 Pwp2p-containing subcomplex of 90S preribosome;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0030686 90S preribosome;GO:0032040 small-subunit processome", "go_biological_process": "GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0030490 maturation of SSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q12220-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12229-1", "uniprot_id": "UBX3_YEAST", "mass": 52943.0, "length": 455, "protein_name": "UBX domain-containing protein 3", "gene_name": "UBX3", "organism": "Yeast", "refseq_name": "clathrin-mediated endocytosis regulator UBX3", "refseq_ac": "NP_010192", "gene_names_uniprotkb": "UBX3", "gene_names_refseq": "UBX3", "protein_names_uniprotkb": "UBX domain-containing protein 3", "protein_names_refseq": "clathrin-mediated endocytosis regulator UBX3", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL091C)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "14562095;14562106;15258615;23749301;24374639;25078903;29355480;32597660;33481703;33491328;8923743;9169867", "class_list": "", "function": "Component of the DSC E3 ubiquitin ligase complexes that tag proteins present in Golgi, endosome and vacuole membranes and function in protein homeostasis under non-stress conditions and support a role in protein quality control (PubMed:25078903, PubMed:29355480). Involved in CDC48-dependent protein degradation through the ubiquitin/proteasome pathway. Involved in delivery of substrates to the 26S proteasome. Also required for membrane fusion (By similarity)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRQ7", "ec_number_list": "", "go_molecular_function": "GO:0030276 clathrin binding;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0030136 clathrin-coated vesicle;GO:0044695 Dsc E3 ubiquitin ligase complex", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0072583 clathrin-dependent endocytosis;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0036503 ERAD pathway;GO:0140624 EGAD pathway", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q12229-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12241-1", "uniprot_id": "VAM3_YEAST", "mass": 32498.0, "length": 283, "protein_name": "Syntaxin VAM3", "gene_name": "VAM3", "organism": "Yeast", "refseq_name": "SNAP receptor VAM3", "refseq_ac": "NP_014749", "gene_names_uniprotkb": "VAM3; PTH1; YOR3220W", "gene_names_refseq": "PTH1; VAM3", "protein_names_uniprotkb": "Syntaxin VAM3; Vacuolar morphogenesis protein 3", "protein_names_refseq": "SNAP receptor VAM3", "tax_id": 559292, "disease": "cancer (Disease Ontology:DOID:162); carcinoma (Disease Ontology:DOID:305)", "pathway": " (sce:YOR106W)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "11224573;14562106;18407956;19795423;19823750;24374639;32597660;33481703;33491328;9169874;9200815;9202390;9245783;9880567", "class_list": "", "function": "Required for vacuolar assembly. Provides the t-SNARE function in a late step of the vacuolar assembly. Required for homotypic vacuole membrane fusion, autophagy and fusion of biosynthetic transport vesicles with the vacuole. Required for the delivery of alpha-factor receptor-ligand complexes to the vacuole., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2G5", "ec_number_list": "", "go_molecular_function": "GO:0000149 SNARE binding;GO:0005484 SNAP receptor activity", "go_cellular_component": "GO:0000421 autophagosome membrane;GO:0012505 endomembrane system;GO:0005774 vacuolar membrane;GO:0031201 SNARE complex;GO:0000329 fungal-type vacuole membrane", "go_biological_process": "GO:0097352 autophagosome maturation;GO:0042144 vacuole fusion, non-autophagic;GO:0006886 intracellular protein transport;GO:0034727 piecemeal microautophagy of the nucleus;GO:0006906 vesicle fusion", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q12241-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12263-1", "uniprot_id": "GIN4_YEAST", "mass": 129858.0, "length": 1142, "protein_name": "Serine/threonine-protein kinase GIN4", "gene_name": "GIN4", "organism": "Yeast", "refseq_name": "protein kinase GIN4", "refseq_ac": "NP_010795", "gene_names_uniprotkb": "GIN4; D9719.13", "gene_names_refseq": "ERC47; GIN4", "protein_names_uniprotkb": "Serine/threonine-protein kinase GIN4; 2.7.11.1; Growth inhibitory protein 4", "protein_names_refseq": "protein kinase GIN4", "tax_id": 559292, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041); depressive disorder (Disease Ontology:DOID:1596)", "pathway": " (sce:YDR507C)", "pathway_count": 1, "publication_count": 25, "publication_id_list": "12058072;14562095;14562106;15665377;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20489023;20702584;21126336;21177495;22218487;23749301;24374639;30516470;32597660;33481703;33491328;9169867;9813093", "class_list": "", "function": "Serine/threonine-protein kinase which regulates the localization and the function of the septins during mitosis. Phosphorylates SHS1., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 94, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "D6VTC9", "ec_number_list": "2.7.11.22;2.7.11.11;2.7.11.1;2.7.12.2;2.7.12.1;2.7.11.24;2.7.11.17;2.7.11.23;2.7.11.25;2.7.11.13;3.1.26.-;2.7.11.21;2.7.1.67;3.6.-.-;3.6.1.-", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000144 cellular bud neck septin ring;GO:0005935 cellular bud neck", "go_biological_process": "GO:0000920 septum digestion after cytokinesis;GO:0000086 G2/M transition of mitotic cell cycle;GO:0000921 septin ring assembly;GO:0007117 budding cell bud growth;GO:0044879 mitotic morphogenesis checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 2.6, "record_id": "Q12263-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12265-1", "uniprot_id": "KPR5_YEAST", "mass": 53505.0, "length": 496, "protein_name": "Ribose-phosphate pyrophosphokinase 5", "gene_name": "PRS5", "organism": "Yeast", "refseq_name": "ribose phosphate diphosphokinase subunit PRS5", "refseq_ac": "NP_014580", "gene_names_uniprotkb": "PRS5; O1213; PRPS5", "gene_names_refseq": "PRS5", "protein_names_uniprotkb": "Ribose-phosphate pyrophosphokinase 5; 2.7.6.1; Phosphoribosyl pyrophosphate synthase 5", "protein_names_refseq": "ribose phosphate diphosphokinase subunit PRS5", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL061W)", "pathway_count": 1, "publication_count": 26, "publication_id_list": "10212224;11875433;14562095;14562106;15280369;15665377;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20702584;21177495;23749301;24374639;32597660;33229814;33481703;33491328;34965436;8789261;9169874;9829955", "class_list": "", "function": "5-phosphoribose 1-diphosphate synthase involved in nucleotide, histidine, and tryptophan biosynthesis. Active in heteromultimeric complexes with other 5-phosphoribose 1-diphosphate synthases (PRS2, PRS3, PRS4 and PRS5)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 21, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 21, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 21, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 27, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 20, "binding_glycan_count": 0, "secondary_ac_list": "D6W206", "ec_number_list": "2.7.6.1", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016301 kinase activity;GO:0004749 ribose phosphate diphosphokinase activity", "go_cellular_component": "GO:0002189 ribose phosphate diphosphokinase complex;GO:0005737 cytoplasm;GO:0097268 cytoophidium", "go_biological_process": "GO:0009156 ribonucleoside monophosphate biosynthetic process;GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process;GO:0006164 purine nucleotide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 4.9, "record_id": "Q12265-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12285-1", "uniprot_id": "MDY2_YEAST", "mass": 23732.0, "length": 212, "protein_name": "Ubiquitin-like protein MDY2", "gene_name": "MDY2", "organism": "Yeast", "refseq_name": "Mdy2p", "refseq_ac": "NP_014530", "gene_names_uniprotkb": "MDY2; GET5; TMA24", "gene_names_refseq": "GET5; MDY2; TMA24", "protein_names_uniprotkb": "Ubiquitin-like protein MDY2; Golgi to ER traffic protein 5; Mating-deficient protein 2; Translation machinery-associated protein 24", "protein_names_refseq": "Mdy2p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL111C)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "10514570;14562095;14562106;16390866;20106980;24374639;33491328;7502582;9169874", "class_list": "", "function": "Required for efficient mating. Involved in the production of alpha-factor, the KAR9 and TUB1 location to the shmoo tip and nuclear migration into pheromone-induced shmoos., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1V6", "ec_number_list": "", "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0010494 cytoplasmic stress granule;GO:0072380 TRC complex", "go_biological_process": "GO:0006620 post-translational protein targeting to endoplasmic reticulum membrane;GO:0045048 protein insertion into ER membrane;GO:0000753 cell morphogenesis involved in conjugation with cellular fusion", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q12285-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12292-1", "uniprot_id": "ATG34_YEAST", "mass": 46655.0, "length": 412, "protein_name": "Autophagy-related protein 34", "gene_name": "ATG34", "organism": "Yeast", "refseq_name": "Atg34p", "refseq_ac": "NP_014558", "gene_names_uniprotkb": "ATG34; ATG19-B; O0957", "gene_names_refseq": "ATG34", "protein_names_uniprotkb": "Autophagy-related protein 34", "protein_names_refseq": "Atg34p", "tax_id": 559292, "disease": "", "pathway": " (sce:YOL083W)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "18407956;19779198;20639194;20659891;24374639;33491328;8533473;9169874", "class_list": "", "function": "Cargo-receptor protein involved in the cytoplasm to vacuole transport (Cvt) and in autophagy. Recognizes cargo proteins, such as AMS1 and delivers them to the pre-autophagosomal structure for eventual engulfment by the autophagosome and targeting to the vacuole., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W1Y5", "ec_number_list": "", "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0034045 phagophore assembly site membrane;GO:0034270 Cvt complex", "go_biological_process": "GO:0016236 macroautophagy;GO:0031503 protein-containing complex localization;GO:0071211 protein targeting to vacuole involved in autophagy;GO:0065003 protein-containing complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q12292-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12309-1", "uniprot_id": "CLF1_YEAST", "mass": 82445.0, "length": 687, "protein_name": "Pre-mRNA-splicing factor CLF1", "gene_name": "CLF1", "organism": "Yeast", "refseq_name": "Clf1p", "refseq_ac": "NP_013218", "gene_names_uniprotkb": "CLF1; L2952; NTC77; SYF3", "gene_names_refseq": "CLF1; NTC77; SYF3", "protein_names_uniprotkb": "Pre-mRNA-splicing factor CLF1; Crooked neck-like factor 1; PRP19-associated complex protein 77; Synthetic lethal with CDC40 protein 3", "protein_names_refseq": "Clf1p", "tax_id": 559292, "disease": "basal cell carcinoma (Disease Ontology:DOID:2513)", "pathway": " (sce:YLR117C)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10445879;11102353;11105756;11842115;11884590;11973290;12088152;12509417;14562095;14562106;14690591;24374639;9090053;9169871", "class_list": "", "function": "Involved in pre-mRNA splicing and cell cycle progression. Required for the spliceosome assembly by promoting the functional integration of the U4/U6.U5 tri-snRNP particle into the U1-, U2-dependent pre-spliceosome. Also recruits PRP19 to the spliceosome, as a component of the NTC complex (or PRP19-associated complex). The association of the NTC complex to the spliceosome mediates conformational rearrangement or stabilizes the structure of the spliceosome after U4 snRNA dissociation, which leads to spliceosome maturation. Required for initiation of the DNA replication by binding the RNA replication origins, probably through its interaction with the origin recognition complex (ORC)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYB5", "ec_number_list": "", "go_molecular_function": "GO:0003688 DNA replication origin binding;GO:0003682 chromatin binding", "go_cellular_component": "GO:0000785 chromatin;GO:0071014 post-mRNA release spliceosomal complex;GO:0071006 U2-type catalytic step 1 spliceosome;GO:0071007 U2-type catalytic step 2 spliceosome;GO:0071008 U2-type post-mRNA release spliceosomal complex", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0006270 DNA replication initiation;GO:0000245 spliceosomal complex assembly;GO:0000354 cis assembly of pre-catalytic spliceosome", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q12309-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12321-1", "uniprot_id": "MED1_YEAST", "mass": 64251.0, "length": 566, "protein_name": "Mediator of RNA polymerase II transcription subunit 1", "gene_name": "MED1", "organism": "Yeast", "refseq_name": "Med1p", "refseq_ac": "NP_015395", "gene_names_uniprotkb": "MED1; YP9499.25; YPR063W", "gene_names_refseq": "MED1", "protein_names_uniprotkb": "Mediator of RNA polymerase II transcription subunit 1; Mediator complex subunit 1", "protein_names_refseq": "Med1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR070W)", "pathway_count": 1, "publication_count": 26, "publication_id_list": "11555651;12191485;14562095;14562106;15175151;15477388;16002404;16076843;16109375;16263706;17192271;17330950;17563356;18407956;19779198;19795423;19823750;20702584;21126336;23749301;24374639;32597660;33481703;33491328;9169875;9892641", "class_list": "", "function": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. The Mediator complex unfolds to an extended conformation and partially surrounds RNA polymerase II, specifically interacting with the unphosphorylated form of the C-terminal domain (CTD) of RNA polymerase II. The Mediator complex dissociates from the RNA polymerase II holoenzyme and stays at the promoter when transcriptional elongation begins., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W474", "ec_number_list": "", "go_molecular_function": "GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016592 mediator complex;GO:0070847 core mediator complex", "go_biological_process": "GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0032968 positive regulation of transcription elongation by RNA polymerase II;GO:0051123 RNA polymerase II preinitiation complex assembly", "synthesized_glycan_count": 0, "hit_score": 2.7, "record_id": "Q12321-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12379-1", "uniprot_id": "SWM1_YEAST", "mass": 19356.0, "length": 170, "protein_name": "Anaphase-promoting complex subunit SWM1", "gene_name": "SWM1", "organism": "Yeast", "refseq_name": "Swm1p", "refseq_ac": "NP_010546", "gene_names_uniprotkb": "SWM1; APC13; YD9320A.11c; YD9320A.11", "gene_names_refseq": "APC13; SWM1", "protein_names_uniprotkb": "Anaphase-promoting complex subunit SWM1; Anaphase-promoting complex subunit 13; Spore wall maturation protein 1", "protein_names_refseq": "Swm1p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDR260C)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "12477395;12609981;15060174;17322287;24374639;32597660;33491328;9169867", "class_list": "", "function": "Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome. In early mitosis, the APC/C is activated by CDC20 and targets securin PDS1, the B-type cyclin CLB5, and other anaphase inhibitory proteins for proteolysis, thereby triggering the separation of sister chromatids at the metaphase-to-anaphase transition. In late mitosis and in G1, degradation of CLB5 allows activation of the APC/C by CDH1, which is needed to destroy CDC20 and the B-type cyclin CLB2 to allow exit from mitosis and creating the low CDK state necessary for cytokinesis and for reforming prereplicative complexes in G1 prior to another round of replication. SWM1 is required for APC/C activity in meiosis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VSP0", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005680 anaphase-promoting complex", "go_biological_process": "GO:0051301 cell division;GO:0007346 regulation of mitotic cell cycle;GO:0016567 protein ubiquitination;GO:0031145 anaphase-promoting complex-dependent catabolic process;GO:0030071 regulation of mitotic metaphase/anaphase transition", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q12379-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12432-1", "uniprot_id": "EAF3_YEAST", "mass": 45203.0, "length": 401, "protein_name": "Chromatin modification-related protein EAF3", "gene_name": "EAF3", "organism": "Yeast", "refseq_name": "Eaf3p", "refseq_ac": "NP_015348", "gene_names_uniprotkb": "EAF3; YP9367.03C", "gene_names_refseq": "EAF3", "protein_names_uniprotkb": "Chromatin modification-related protein EAF3; ESA1-associated factor 3", "protein_names_refseq": "Eaf3p", "tax_id": 559292, "disease": "", "pathway": " (sce:YPR023C)", "pathway_count": 1, "publication_count": 21, "publication_id_list": "11036083;14562095;14562106;14701747;15045029;15353583;15485911;17563356;18407956;19779198;19795423;19823750;20190278;21126336;23749301;24374639;30516470;33229814;33481703;33491328;9169875", "class_list": "", "function": "Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 12, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 12, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 12, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 15, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 11, "binding_glycan_count": 0, "secondary_ac_list": "D6W433", "ec_number_list": "", "go_molecular_function": "GO:0140566 histone reader activity;GO:0140003 histone H3K36me3 reader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0035267 NuA4 histone acetyltransferase complex;GO:0000123 histone acetyltransferase complex;GO:0032221 Rpd3S complex", "go_biological_process": "GO:0030174 regulation of DNA-templated DNA replication initiation;GO:0043487 regulation of RNA stability;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006281 DNA repair;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 3.5, "record_id": "Q12432-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12434-1", "uniprot_id": "GDIR_YEAST", "mass": 23138.0, "length": 202, "protein_name": "Rho GDP-dissociation inhibitor", "gene_name": "RDI1", "organism": "Yeast", "refseq_name": "Rdi1p", "refseq_ac": "NP_010146", "gene_names_uniprotkb": "RDI1; D2175", "gene_names_refseq": "RDI1", "protein_names_uniprotkb": "Rho GDP-dissociation inhibitor; Rho GDI", "protein_names_refseq": "Rdi1p", "tax_id": 559292, "disease": "nephrotic syndrome type 8 (Disease Ontology:DOID:0080389); hypertension (Disease Ontology:DOID:10763); nephrotic syndrome (Disease Ontology:DOID:1184)", "pathway": " (sce:YDL135C); (R-SCE-8980692); (R-SCE-9013106); (R-SCE-9013148); (R-SCE-9013149); (R-SCE-9013423)", "pathway_count": 6, "publication_count": 21, "publication_id_list": "14562106;17287358;17322287;17330950;17563356;18407956;19779198;19795423;19823750;20702584;21126336;21177495;22218487;22814378;23749301;24374639;33481703;33491328;8051050;8972577;9169867", "class_list": "", "function": "Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRL3", "ec_number_list": "", "go_molecular_function": "GO:0005094 Rho GDP-dissociation inhibitor activity;GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0005934 cellular bud tip;GO:0005935 cellular bud neck", "go_biological_process": "GO:0007015 actin filament organization;GO:0007266 Rho protein signal transduction;GO:0032889 regulation of vacuole fusion, non-autophagic", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "Q12434-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12446-1", "uniprot_id": "LAS17_YEAST", "mass": 67572.0, "length": 633, "protein_name": "Proline-rich protein LAS17", "gene_name": "LAS17", "organism": "Yeast", "refseq_name": "actin-binding protein LAS17", "refseq_ac": "NP_014824", "gene_names_uniprotkb": "LAS17", "gene_names_refseq": "BEE1; LAS17", "protein_names_uniprotkb": "Proline-rich protein LAS17", "protein_names_refseq": "actin-binding protein LAS17", "tax_id": 559292, "disease": "X-linked severe congenital neutropenia (Disease Ontology:DOID:0112128); thrombocytopenia (Disease Ontology:DOID:1588); IgA glomerulonephritis (Disease Ontology:DOID:2986); Wiskott-Aldrich syndrome (Disease Ontology:DOID:9169)", "pathway": " (sce:YOR181W)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10512884;12237851;14562106;17563356;18407956;19779198;23749301;24374639;32597660;33229814;33481703;33491328;33958621;9169874", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 11, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 11, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 11, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 4, "glyco_site_count": 12, "binding_glycan_count": 0, "secondary_ac_list": "D6W2N7", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0031267 small GTPase binding;GO:0071933 Arp2/3 complex binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0030479 actin cortical patch;GO:0140224 SLAC complex;GO:0043332 mating projection tip", "go_biological_process": "GO:0032233 positive regulation of actin filament bundle assembly;GO:0007015 actin filament organization;GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation;GO:0030041 actin filament polymerization;GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation", "synthesized_glycan_count": 0, "hit_score": 2.7, "record_id": "Q12446-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12460-1", "uniprot_id": "NOP56_YEAST", "mass": 56864.0, "length": 504, "protein_name": "Nucleolar protein 56", "gene_name": "NOP56", "organism": "Yeast", "refseq_name": "snoRNP complex protein NOP56", "refseq_ac": "NP_013298", "gene_names_uniprotkb": "NOP56; L8167.9; SIK1", "gene_names_refseq": "NOP56; SIK1", "protein_names_uniprotkb": "Nucleolar protein 56; Ribosome biosynthesis protein SIK1; Suppressor of I kappa b protein 1", "protein_names_refseq": "snoRNP complex protein NOP56", "tax_id": 559292, "disease": "spinocerebellar ataxia 36 (Disease Ontology:DOID:0050983)", "pathway": " (sce:YLR197W); (R-SCE-6791226)", "pathway_count": 2, "publication_count": 16, "publication_id_list": "12068309;14562106;17563356;18407956;19684113;19795423;19823750;21126336;23749301;24374639;32597660;33481703;33491328;7547500;9169871;9372940", "class_list": "", "function": "Required for 60S ribosomal subunit synthesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VYK0", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0030515 snoRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0031428 box C/D methylation guide snoRNP complex;GO:0030686 90S preribosome", "go_biological_process": "GO:0000154 rRNA modification;GO:0006364 rRNA processing;GO:0000494 box C/D sno(s)RNA 3'-end processing;GO:0030490 maturation of SSU-rRNA;GO:0000452 snoRNA guided rRNA 2'-O-methylation", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q12460-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12461-1", "uniprot_id": "PTPA2_YEAST", "mass": 41452.0, "length": 358, "protein_name": "Serine/threonine-protein phosphatase 2A activator 2", "gene_name": "RRD2", "organism": "Yeast", "refseq_name": "peptidylprolyl isomerase RRD2", "refseq_ac": "NP_015173", "gene_names_uniprotkb": "RRD2; NOH1; YPA2", "gene_names_refseq": "RRD2; YPA2", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase 2A activator 2; 5.2.1.8; PPIase PTPA-2; Peptidyl-prolyl cis-trans isomerase PTPA-2; Phosphotyrosyl phosphatase activator 2; Rotamase PTPA-2", "protein_names_refseq": "peptidylprolyl isomerase RRD2", "tax_id": 559292, "disease": "Parkinson's disease 25 (Disease Ontology:DOID:0070486)", "pathway": " (sce:YPL152W)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "11134337;11262194;12952889;14562095;14562106;15447631;15689491;16380387;24374639;33491328;8948103;9169875", "class_list": "", "function": "PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for TAP42-associated PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex. Acts also inhibitory at high concentrations. Involved in the regulation of cell cycle progression, mitotic spindle formation and bud morphogenesis., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3L7", "ec_number_list": "5.2.1.8", "go_molecular_function": "GO:0019888 protein phosphatase regulator activity;GO:0008160 protein tyrosine phosphatase activator activity;GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000159 protein phosphatase type 2A complex", "go_biological_process": "GO:0006970 response to osmotic stress;GO:0031929 TOR signaling;GO:0007052 mitotic spindle organization", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q12461-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12464-1", "uniprot_id": "RUVB2_YEAST", "mass": 51612.0, "length": 471, "protein_name": "RuvB-like protein 2", "gene_name": "RVB2", "organism": "Yeast", "refseq_name": "RuvB family ATP-dependent DNA helicase reptin", "refseq_ac": "NP_015089", "gene_names_uniprotkb": "RVB2; P1060; TIH2; TIP49B", "gene_names_refseq": "RVB2; TIH2; TIP48; TIP49B", "protein_names_uniprotkb": "RuvB-like protein 2; 3.6.4.12; RUVBL2; TIP49-homology protein 2; TIP49b homolog", "protein_names_refseq": "RuvB family ATP-dependent DNA helicase reptin", "tax_id": 559292, "disease": "", "pathway": " (sce:YPL235W)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "10787406;10952318;11278922;11604509;12576485;14562106;14645854;14690591;14690608;15045029;15525518;15766533;18407956;21126336;23749301;24374639;32597660;33481703;33491328;9169875", "class_list": "", "function": "DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes. Its ability to induce transcription of some phosphate-responsive genes is modulated by inositol polyphosphates. The INO80 complex is involved in DNA repair by associating to 'Ser-129' phosphorylated H2A histones as a response to DNA damage. During transcription may recruit SPT15/TBP to the TATA-boxes of involved genes. Required for box C/D and box H/ACA snoRNA accumulation and involved in pre-rRNA processing., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W3D5", "ec_number_list": "3.6.4.13;5.6.2.3;3.6.4.10;3.6.-.-;5.6.2.4;3.6.4.-;5.6.1.4;3.6.4.12;3.6.4.6;5.6.2.5;3.6.1.-;2.3.2.27;3.1.-.-;3.4.24.-;3.6.5.-;2.7.4.3;2.7.11.1;7.2.2.-", "go_molecular_function": "GO:0043138 3'-5' DNA helicase activity;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003678 DNA helicase activity;GO:0043139 5'-3' DNA helicase activity", "go_cellular_component": "GO:0097255 R2TP complex;GO:0005634 nucleus;GO:0031011 Ino80 complex;GO:0035267 NuA4 histone acetyltransferase complex;GO:0000785 chromatin", "go_biological_process": "GO:0006281 DNA repair;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "Q12464-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12477-1", "uniprot_id": "PCL9_YEAST", "mass": 34798.0, "length": 304, "protein_name": "PHO85 cyclin-9", "gene_name": "PCL9", "organism": "Yeast", "refseq_name": "Pcl9p", "refseq_ac": "NP_010102", "gene_names_uniprotkb": "PCL9; D1408", "gene_names_refseq": "PCL9", "protein_names_uniprotkb": "PHO85 cyclin-9", "protein_names_refseq": "Pcl9p", "tax_id": 559292, "disease": "", "pathway": " (sce:YDL179W)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "17322287;24374639;9032248;9169867;9529390;9593297", "class_list": "", "function": "M/G1-specific cyclin partner of the cyclin-dependent kinase (CDK) PHO85. May have a role in bud site selection in G1 phase., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6VRH3", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding;GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000307 cyclin-dependent protein kinase holoenzyme complex;GO:0000131 incipient cellular bud site;GO:0005935 cellular bud neck", "go_biological_process": "GO:0032878 regulation of establishment or maintenance of cell polarity;GO:0006357 regulation of transcription by RNA polymerase II;GO:0051301 cell division;GO:0006355 regulation of DNA-templated transcription;GO:0000082 G1/S transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q12477-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q12481-1", "uniprot_id": "RRP36_YEAST", "mass": 36125.0, "length": 300, "protein_name": "rRNA biogenesis protein RRP36", "gene_name": "RRP36", "organism": "Yeast", "refseq_name": "rRNA-processing protein RRP36", "refseq_ac": "NP_014930", "gene_names_uniprotkb": "RRP36", "gene_names_refseq": "RRP36", "protein_names_uniprotkb": "rRNA biogenesis protein RRP36; Ribosomal RNA-processing protein 36", "protein_names_refseq": "rRNA-processing protein RRP36", "tax_id": 559292, "disease": "", "pathway": " (sce:YOR287C); (R-SCE-6791226)", "pathway_count": 2, "publication_count": 21, "publication_id_list": "16544271;17287358;17330950;17563356;18407956;19684113;19779198;19795423;19823750;20038530;20702584;21177495;23749301;24374639;27821475;30516470;32597660;33481703;33491328;8896271;9169874", "class_list": "", "function": "Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D6W2Y5", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0030686 90S preribosome", "go_biological_process": "GO:0006364 rRNA processing;GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0042274 ribosomal small subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "Q12481-1", "record_type": "protein" } ]