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        "length": 1183,
        "protein_name": "Histone-lysine N-methyltransferase EHMT2 isoform X1",
        "gene_name": "ehmt2",
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        "refseq_ac": "NP_001428432",
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        "protein_names_uniprotkb": "Histone-lysine N-methyltransferase EHMT2 isoform X1",
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        "gene_names_uniprotkb": "col14a1b",
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        "protein_names_refseq": "collagen alpha-1(XIV) chain isoform X4",
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        "length": 813,
        "protein_name": "[histone-H3]-N(6),N(6)-dimethyl-L-lysine(4) FAD-dependent demethylase",
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        "protein_names_refseq": "lysine-specific histone demethylase 2 isoform X1",
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        "protein_name": "A-kinase anchor protein 9 isoform X1",
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        "protein_name": "F-actin-uncapping protein LRRC16A isoform X1",
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        "protein_names_refseq": "F-actin-uncapping protein LRRC16A isoform X1",
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        "protein_name": "Zinc transporter ZIP4",
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        "protein_names_refseq": "zinc transporter ZIP4 isoform X1",
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        "protein_name": "Solute carrier family 45 member 4",
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        "length": 269,
        "protein_name": "Secretagogin",
        "gene_name": "LOC141378952",
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        "length": 871,
        "protein_name": "Reverse transcriptase domain-containing protein",
        "gene_name": "LOC141379022",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": "XP_073778421",
        "gene_names_uniprotkb": "LOC141379022; LOC141377611",
        "gene_names_refseq": "LOC141377611",
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        "protein_names_refseq": "uncharacterized protein",
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        "uniprot_id": "A0AC58I091_DANRE",
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        "length": 1847,
        "protein_name": "Regulating synaptic membrane exocytosis protein 2 isoform X1",
        "gene_name": "rims2b",
        "organism": "Zebrafish",
        "refseq_name": "regulating synaptic membrane exocytosis protein 2 isoform X1",
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        "protein_names_refseq": "regulating synaptic membrane exocytosis protein 2 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "missing_score": 10000,
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        "record_id": "A0AC58I091-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58I375-1",
        "uniprot_id": "A0AC58I375_DANRE",
        "mass": 167077.0,
        "length": 1505,
        "protein_name": "Sterile alpha motif domain-containing protein 5",
        "gene_name": "sash1a",
        "organism": "Zebrafish",
        "refseq_name": "SAM and SH3 domain-containing protein 1a isoform 2",
        "refseq_ac": "NP_001429142",
        "gene_names_uniprotkb": "sash1a; fi33a01; ik:tdsubc_2e1; si:dkey-264g21.1; tdsubc_2e1; wu:fi33a01; xx:tdsubc_2e1",
        "gene_names_refseq": "fi33a01; ik:tdsubc_2e1; sash1a; si:dkey-264g21.1; tdsubc_2e1; wu:fi33a01; xx:tdsubc_2e1",
        "protein_names_uniprotkb": "Sterile alpha motif domain-containing protein 5",
        "protein_names_refseq": "SAM and SH3 domain containing 1; SAM and SH3 domain-containing protein 1a isoform 2",
        "tax_id": 7955,
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        "publication_id_list": "37741309",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588730.21410516.1, SRR32588721.3997726.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1. On Jul 30, 2025 this sequence version replaced XP_073788681.1., [RefSeq]; SASH1 contributes to glial cell migration in the early development of the central nervous system., [RefSeq, PubMed]",
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        "missing_score": 10000,
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        "go_cellular_component": "GO:0005737 cytoplasm",
        "go_biological_process": "GO:0036269 swimming behavior;GO:0014002 astrocyte development",
        "synthesized_glycan_count": 0,
        "hit_score": 0.2,
        "record_id": "A0AC58I375-1",
        "record_type": "protein"
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    {
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        "uniprot_id": "A0AC58I1W7_DANRE",
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        "length": 594,
        "protein_name": "BTB/POZ domain-containing protein 2 isoform X1",
        "gene_name": "btbd2b",
        "organism": "Zebrafish",
        "refseq_name": "BTB/POZ domain-containing protein 2 isoform X1",
        "refseq_ac": "XP_073788225",
        "gene_names_uniprotkb": "btbd2b",
        "gene_names_refseq": "btbd2b",
        "protein_names_uniprotkb": "BTB/POZ domain-containing protein 2 isoform X1",
        "protein_names_refseq": "BTB/POZ domain-containing protein 2 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:555499);  (R-DRE-8951664);  (R-DRE-983168)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "go_molecular_function": "",
        "go_cellular_component": "GO:0005829 cytosol;GO:0000932 P-body",
        "go_biological_process": "GO:0022008 neurogenesis",
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        "record_id": "A0AC58I1W7-1",
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        "uniprot_canonical_ac": "A0AC58I1B9-1",
        "uniprot_id": "A0AC58I1B9_DANRE",
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        "length": 562,
        "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25-like isoform X2",
        "gene_name": "ftr30",
        "organism": "Zebrafish",
        "refseq_name": "E3 ubiquitin/ISG15 ligase TRIM25-like isoform X2",
        "refseq_ac": "XP_073788008",
        "gene_names_uniprotkb": "ftr30",
        "gene_names_refseq": "ftr30",
        "protein_names_uniprotkb": "E3 ubiquitin/ISG15 ligase TRIM25-like isoform X2",
        "protein_names_refseq": "E3 ubiquitin/ISG15 ligase TRIM25-like isoform X2",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio                   :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0008270 zinc ion binding",
        "go_cellular_component": "GO:0005737 cytoplasm",
        "go_biological_process": "GO:0045087 innate immune response",
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        "record_id": "A0AC58I1B9-1",
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        "protein_name": "Trace amine associated receptor 14a isoform X1",
        "gene_name": "taar14a",
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        "refseq_name": "trace amine associated receptor 14a isoform X1",
        "refseq_ac": "XP_073788131",
        "gene_names_uniprotkb": "taar14a; si:dkey-246e3.1",
        "gene_names_refseq": "si:dkey-246e3.1; taar14a",
        "protein_names_uniprotkb": "Trace amine associated receptor 14a isoform X1",
        "protein_names_refseq": "trace amine associated receptor 14a isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100034373);  (R-DRE-375280)",
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        "publication_id_list": "19237578;26108469",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "GO:0001594 trace-amine receptor activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway",
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        "hit_score": 0.3,
        "record_id": "A0AC58I1P4-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58I3A7-1",
        "uniprot_id": "A0AC58I3A7_DANRE",
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        "length": 487,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "si:ch211-199m3.1",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein LOC557251",
        "refseq_ac": "NP_001038287",
        "gene_names_uniprotkb": "si:ch211-199m3.1",
        "gene_names_refseq": "si:ch211-199m3.1",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein LOC557251",
        "tax_id": 7955,
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        "pathway": " (dre:557251)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588722.30873080.1, SRR32588728.3426377.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN18715719, SAMN18715720 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1. On or before Sep 16, 2025 this sequence version replaced XP_073788707.1, NP_001038287.1., [RefSeq]",
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    {
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        "mass": 359703.0,
        "length": 3216,
        "protein_name": "Protein furry homolog-like isoform X1",
        "gene_name": "fryl",
        "organism": "Zebrafish",
        "refseq_name": "protein furry homolog-like isoform X1",
        "refseq_ac": "XP_073788777",
        "gene_names_uniprotkb": "fryl; fc84g03; im:6912409; si:dkey-90m5.7; wu:fc84g03",
        "gene_names_refseq": "fc84g03; fryl; im:6912409; si:dkey-90m5.7; wu:fc84g03",
        "protein_names_uniprotkb": "Protein furry homolog-like isoform X1",
        "protein_names_refseq": "protein furry homolog-like isoform X1",
        "tax_id": 7955,
        "disease": "syndromic intellectual disability (Disease Ontology:DOID:0050888); Pan-Chung-Bellen syndrome (Disease Ontology:DOID:0061146)",
        "pathway": " (dre:558173)",
        "pathway_count": 1,
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        "publication_id_list": "15520368;21147602;25533962;26469318;27189481;28252024;30174136",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_biological_process": "GO:0007507 heart development;GO:0000902 cell morphogenesis",
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    {
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        "uniprot_id": "A0AC58I0Y0_DANRE",
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        "length": 763,
        "protein_name": "Terminal nucleotidyltransferase 4A",
        "gene_name": "tent4a",
        "organism": "Zebrafish",
        "refseq_name": "terminal nucleotidyltransferase 4A isoform X1",
        "refseq_ac": "XP_073787879",
        "gene_names_uniprotkb": "tent4a",
        "gene_names_refseq": "tent4a",
        "protein_names_uniprotkb": "Terminal nucleotidyltransferase 4A; 2.7.7.19; DNA polymerase sigma; Non-canonical poly(A) RNA polymerase PAPD7; PAP-associated domain-containing protein 7; TRAMP-like complex polyadenylate polymerase; Terminal guanylyltransferase",
        "protein_names_refseq": "terminal nucleotidyltransferase 4A isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:557829)",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Terminal nucleotidyltransferase that catalyzes preferentially the transfer of ATP and GTP on RNA 3' poly(A) tail creating a heterogeneous 3' poly(A) tail leading to mRNAs stabilization by protecting mRNAs from active deadenylation. Also functions as a catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Has no terminal uridylyltransferase activity, and does not play a role in replication-dependent histone mRNA degradation via uridylation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0046872 metal ion binding;GO:1990817 poly(A) RNA polymerase activity;GO:0070568 guanylyltransferase activity",
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        "go_biological_process": "GO:1905870 positive regulation of 3'-UTR-mediated mRNA stabilization;GO:0060212 negative regulation of nuclear-transcribed mRNA poly(A) tail shortening",
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    {
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        "mass": 114244.0,
        "length": 1021,
        "protein_name": "Voltage-gated delayed rectifier potassium channel KCNH4",
        "gene_name": "kcnh8",
        "organism": "Zebrafish",
        "refseq_name": "voltage-gated delayed rectifier potassium channel KCNH8 isoform X1",
        "refseq_ac": "XP_073787754",
        "gene_names_uniprotkb": "kcnh8",
        "gene_names_refseq": "kcnh8",
        "protein_names_uniprotkb": "Voltage-gated delayed rectifier potassium channel KCNH4; Brain-specific eag-like channel 2; Ether-a-go-go-like potassium channel 1; Potassium voltage-gated channel subfamily H member 4; Voltage-gated potassium channel subunit Kv12.3",
        "protein_names_refseq": "voltage-gated delayed rectifier potassium channel KCNH8 isoform X1",
        "tax_id": 7955,
        "disease": "retinal degeneration (Disease Ontology:DOID:8466)",
        "pathway": " (dre:100002967)",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Pore-forming (alpha) subunit of a voltage-gated delayed rectifier. Activates at more negative voltages, exhibits fast prepulse-independent activation kinetics and deactivates much more slowly, but shows no inactivation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
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        "secondary_ac_list": "A0AC58I0J1",
        "ec_number_list": "2.7.11.1;1.5.1.2",
        "go_molecular_function": "GO:0005249 voltage-gated potassium channel activity",
        "go_cellular_component": "GO:0034702 monoatomic ion channel complex",
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    {
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        "uniprot_id": "A0AC58I2J2_DANRE",
        "mass": 37821.0,
        "length": 347,
        "protein_name": "DNA repair protein RAD51 homolog",
        "gene_name": "rad51",
        "organism": "Zebrafish",
        "refseq_name": "DNA repair protein RAD51 homolog 1 isoform X1",
        "refseq_ac": "XP_073788437",
        "gene_names_uniprotkb": "rad51; wu:fb38e12; zgc:77754",
        "gene_names_refseq": "rad51; wu:fb38e12; zgc:77754",
        "protein_names_uniprotkb": "DNA repair protein RAD51 homolog",
        "protein_names_refseq": "DNA repair protein RAD51 homolog 1 isoform X1",
        "tax_id": 7955,
        "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); mirror movements 2 (Disease Ontology:DOID:0070637); Fanconi anemia complementation group R (Disease Ontology:DOID:0111090); hypertension (Disease Ontology:DOID:10763); Fanconi anemia (Disease Ontology:DOID:13636); breast cancer (Disease Ontology:DOID:1612); pancreatic cancer (Disease Ontology:DOID:1793); ovarian cancer (Disease Ontology:DOID:2394); primary ovarian insufficiency (Disease Ontology:DOID:5426)",
        "pathway": " (dre:406487);  (R-DRE-5685938);  (R-DRE-5685942);  (R-DRE-5693537);  (R-DRE-5693568);  (R-DRE-5693579);  (R-DRE-5693616);  (R-DRE-912446)",
        "pathway_count": 8,
        "publication_count": 10,
        "publication_id_list": "15984772;16109975;16799861;18764902;19146232;34390914;35269606;35341844;35461948;36208295",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Recruited to resolve stalled replication forks during replication stress. Also involved in interstrand cross-link repair., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0005524 ATP binding;GO:0003690 double-stranded DNA binding;GO:0003697 single-stranded DNA binding;GO:0008094 ATP-dependent activity, acting on DNA;GO:0000150 DNA strand exchange activity",
        "go_cellular_component": "GO:0000794 condensed nuclear chromosome",
        "go_biological_process": "GO:0006312 mitotic recombination;GO:0046686 response to cadmium ion;GO:0000724 double-strand break repair via homologous recombination;GO:0051597 response to methylmercury;GO:0071425 hematopoietic stem cell proliferation",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0AC58I2J2-1",
        "record_type": "protein"
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    {
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        "uniprot_id": "A0AC58I1M8_DANRE",
        "mass": 52746.0,
        "length": 470,
        "protein_name": "non-specific serine/threonine protein kinase",
        "gene_name": "pimr133",
        "organism": "Zebrafish",
        "refseq_name": "pim proto-oncogene, serine/threonine kinase, related 133 isoform X1",
        "refseq_ac": "XP_073788133",
        "gene_names_uniprotkb": "pimr133; si:dkey-197d18.1",
        "gene_names_refseq": "pimr133; si:dkey-197d18.1",
        "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1",
        "protein_names_refseq": "pim proto-oncogene, serine/threonine kinase, related 133 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100034408)",
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        "publication_id_list": "27011661",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "ec_number_list": "2.7.11.1;2.7.11.13;2.7.11.25;2.7.10.1;2.7.11.22;2.7.11.21;2.7.11.17;2.7.12.1;2.7.12.2;2.7.11.24;2.7.10.2;2.7.11.23;2.7.1.150;2.7.11.12;2.7.11.39;2.7.11.11;2.7.1.153;2.7.1.137;2.7.1.154;2.7.11.26;2.7.11.31",
        "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0016301 kinase activity",
        "go_cellular_component": "GO:0005737 cytoplasm",
        "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0007346 regulation of mitotic cell cycle",
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    {
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        "mass": 50455.0,
        "length": 467,
        "protein_name": "One cut domain family member 2 isoform X1",
        "gene_name": "onecut3b",
        "organism": "Zebrafish",
        "refseq_name": "one cut domain family member 2 isoform X1",
        "refseq_ac": "XP_073788243",
        "gene_names_uniprotkb": "onecut3b",
        "gene_names_refseq": "onecut3b",
        "protein_names_uniprotkb": "One cut domain family member 2 isoform X1",
        "protein_names_refseq": "one cut domain family member 2 isoform X1",
        "tax_id": 7955,
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        "pathway": " (dre:100332965)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II",
        "synthesized_glycan_count": 0,
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        "record_type": "protein"
    },
    {
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        "length": 502,
        "protein_name": "Gap junction protein",
        "gene_name": "gja10b",
        "organism": "Zebrafish",
        "refseq_name": "gap junction alpha-10 protein isoform X1",
        "refseq_ac": "XP_073788381",
        "gene_names_uniprotkb": "gja10b; cx52.6",
        "gene_names_refseq": "cx52.6; gja10b",
        "protein_names_uniprotkb": "Gap junction protein",
        "protein_names_refseq": "gap junction alpha-10 protein isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0055077 gap junction hemi-channel activity;GO:0005243 gap junction channel activity",
        "go_cellular_component": "GO:0005921 gap junction;GO:0005922 connexin complex",
        "go_biological_process": "GO:0007267 cell-cell signaling",
        "synthesized_glycan_count": 0,
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        "record_id": "A0AC58I2B7-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58I2V4-1",
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        "mass": 51184.0,
        "length": 468,
        "protein_name": "Transcription factor AP-2-beta isoform X1",
        "gene_name": "tfap2b",
        "organism": "Zebrafish",
        "refseq_name": "transcription factor AP-2-beta isoform X1",
        "refseq_ac": "XP_073788562",
        "gene_names_uniprotkb": "tfap2b; si:dkey-5e16.1; zgc:110163",
        "gene_names_refseq": "si:dkey-5e16.1; tfap2b; zgc:110163",
        "protein_names_uniprotkb": "Transcription factor AP-2-beta isoform X1",
        "protein_names_refseq": "transcription factor AP-2-beta isoform X1",
        "tax_id": 7955,
        "disease": "Char syndrome (Disease Ontology:DOID:0060563); angle-closure glaucoma (Disease Ontology:DOID:13550); patent ductus arteriosus (Disease Ontology:DOID:13832); sleep disorder (Disease Ontology:DOID:535)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0030432 peristalsis;GO:0048484 enteric nervous system development;GO:0006351 DNA-templated transcription;GO:0007399 nervous system development;GO:0042127 regulation of cell population proliferation",
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        "hit_score": 0.1,
        "record_id": "A0AC58I2V4-1",
        "record_type": "protein"
    },
    {
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        "uniprot_id": "A0AC58I2W8_DANRE",
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        "length": 748,
        "protein_name": "Proteoglycan 4b isoform X1",
        "gene_name": "prg4b",
        "organism": "Zebrafish",
        "refseq_name": "proteoglycan 4b isoform X1",
        "refseq_ac": "XP_073788577",
        "gene_names_uniprotkb": "prg4b; prg4; si:dkey-97o5.3; zgc:122988",
        "gene_names_refseq": "prg4b; prg4; si:dkey-97o5.3; zgc:122988",
        "protein_names_uniprotkb": "Proteoglycan 4b isoform X1",
        "protein_names_refseq": "proteoglycan 4b isoform X1",
        "tax_id": 7955,
        "disease": "camptodactyly-arthropathy-coxa vara-pericarditis syndrome (Disease Ontology:DOID:0090127); pericarditis (Disease Ontology:DOID:1787)",
        "pathway": " (dre:553377)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 7,
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        "go_molecular_function": "GO:0030247 polysaccharide binding;GO:0005044 scavenger receptor activity",
        "go_cellular_component": "GO:0005576 extracellular region",
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    {
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        "uniprot_id": "A0AC58I1U1_DANRE",
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        "length": 701,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "si:ch211-191a24.4",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073788205",
        "gene_names_uniprotkb": "si:ch211-191a24.4; fd10g01; wu:fd10g01",
        "gene_names_refseq": "fd10g01; si:ch211-191a24.4; wu:fd10g01",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100150331)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_cellular_component": "GO:0016020 membrane;GO:0005847 mRNA cleavage and polyadenylation specificity factor complex",
        "go_biological_process": "GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage",
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    {
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        "length": 605,
        "protein_name": "Phosphatase and actin regulator",
        "gene_name": "phactr1",
        "organism": "Zebrafish",
        "refseq_name": "phosphatase and actin regulator 1 isoform X1",
        "refseq_ac": "XP_073788213",
        "gene_names_uniprotkb": "phactr1",
        "gene_names_refseq": "phactr1",
        "protein_names_uniprotkb": "Phosphatase and actin regulator",
        "protein_names_refseq": "phosphatase and actin regulator 1 isoform X1",
        "tax_id": 7955,
        "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); developmental and epileptic encephalopathy 70 (Disease Ontology:DOID:0112206); essential hypertension (Disease Ontology:DOID:10825); Moyamoya disease (Disease Ontology:DOID:13099); coronary artery disease (Disease Ontology:DOID:3393); cerebral infarction (Disease Ontology:DOID:3526); coronary stenosis (Disease Ontology:DOID:4248); myocardial infarction (Disease Ontology:DOID:5844); migraine (Disease Ontology:DOID:6364)",
        "pathway": " (dre:100334776)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0003779 actin binding;GO:0004864 protein phosphatase inhibitor activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0045202 synapse",
        "go_biological_process": "GO:0001944 vasculature development",
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    {
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        "length": 482,
        "protein_name": "Endonuclease/exonuclease/phosphatase domain-containing protein",
        "gene_name": "LOC141379047",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": "XP_073787710",
        "gene_names_uniprotkb": "LOC141379047",
        "gene_names_refseq": "LOC141379047",
        "protein_names_uniprotkb": "Endonuclease/exonuclease/phosphatase domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "gene_names_uniprotkb": "si:ch73-367f21.4",
        "gene_names_refseq": "si:ch73-367f21.4",
        "protein_names_uniprotkb": "Uncharacterized protein si:ch73-367f21.4",
        "protein_names_refseq": "uncharacterized protein si:ch73-367f21.4",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio                   :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]",
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        "missing_score": 10000,
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        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58I134-1",
        "record_type": "protein"
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        "uniprot_canonical_ac": "A0AC58I167-1",
        "uniprot_id": "A0AC58I167_DANRE",
        "mass": 88042.0,
        "length": 774,
        "protein_name": "Retrotransposon Pao-like RNAseH-like domain-containing protein",
        "gene_name": "LOC141379163",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": "XP_073787972",
        "gene_names_uniprotkb": "LOC141379163",
        "gene_names_refseq": "LOC141379163",
        "protein_names_uniprotkb": "Retrotransposon Pao-like RNAseH-like domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "missing_score": 10000,
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        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58I167-1",
        "record_type": "protein"
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        "uniprot_id": "A0AC58I182_DANRE",
        "mass": 141550.0,
        "length": 1262,
        "protein_name": "Gypsy retrotransposon integrase-like protein 1",
        "gene_name": "LOC141379172",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": "XP_073788012",
        "gene_names_uniprotkb": "LOC141379172",
        "gene_names_refseq": "LOC141379172",
        "protein_names_uniprotkb": "Gypsy retrotransposon integrase-like protein 1; 3.1.26.4",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
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        "publication_id_list": "",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58I182-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58I185-1",
        "uniprot_id": "A0AC58I185_DANRE",
        "mass": 70950.0,
        "length": 614,
        "protein_name": "Calcitonin gene-related peptide type 1 receptor",
        "gene_name": "calcr",
        "organism": "Zebrafish",
        "refseq_name": "calcitonin receptor",
        "refseq_ac": "XP_073788004",
        "gene_names_uniprotkb": "calcr",
        "gene_names_refseq": "calcr",
        "protein_names_uniprotkb": "Calcitonin gene-related peptide type 1 receptor; Calcitonin receptor-like receptor",
        "protein_names_refseq": "calcitonin receptor",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May function as G protein-coupled receptor for calcitonin-gene-related peptides and adrenomedullin. Specificity may be modulated by accessory proteins. May activate cAMP-dependent pathway., [UniProtKB, UniProtKB]",
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
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        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58I185-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58I1C6-1",
        "uniprot_id": "A0AC58I1C6_DANRE",
        "mass": 70648.0,
        "length": 631,
        "protein_name": "Cytoplasmic dynein 1 intermediate chain 1 isoform X1",
        "gene_name": "dync1i1a",
        "organism": "Zebrafish",
        "refseq_name": "cytoplasmic dynein 1 intermediate chain 1 isoform X1",
        "refseq_ac": "XP_073788024",
        "gene_names_uniprotkb": "dync1i1a",
        "gene_names_refseq": "dync1i1a",
        "protein_names_uniprotkb": "Cytoplasmic dynein 1 intermediate chain 1 isoform X1",
        "protein_names_refseq": "cytoplasmic dynein 1 intermediate chain 1 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "uniprot_id": "A0AC58I198_DANRE",
        "mass": 59998.0,
        "length": 530,
        "protein_name": "Uncharacterized protein",
        "gene_name": "LOC141379165",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": "XP_073788000",
        "gene_names_uniprotkb": "LOC141379165",
        "gene_names_refseq": "LOC141379165",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "record_id": "A0AC58I198-1",
        "record_type": "protein"
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    {
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        "uniprot_id": "A0AC58I1A1_DANRE",
        "mass": 76950.0,
        "length": 680,
        "protein_name": "Potassium voltage-gated channel subfamily KQT member 4",
        "gene_name": "kcnq4",
        "organism": "Zebrafish",
        "refseq_name": "potassium voltage-gated channel subfamily KQT member 4",
        "refseq_ac": "XP_073788019",
        "gene_names_uniprotkb": "kcnq4",
        "gene_names_refseq": "kcnq4",
        "protein_names_uniprotkb": "Potassium voltage-gated channel subfamily KQT member 4",
        "protein_names_refseq": "potassium voltage-gated channel subfamily KQT member 4",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": "2.7.11.1;1.5.1.2",
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58I1A1-1",
        "record_type": "protein"
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        "protein_name": "Prolyl endopeptidase",
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        "gene_name": "tnxbb",
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        "refseq_name": "uncharacterized protein tnxbb",
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        "protein_name": "Cilia- and flagella-associated protein 44",
        "gene_name": "cfap44",
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        "protein_name": "DNA-directed RNA polymerases I, II, and III subunit RPABC1",
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        "gene_names_refseq": "polr2ea",
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        "protein_names_refseq": "DNA-directed RNA polymerases I, II, and III subunit RPABC1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_cellular_component": "GO:0000428 DNA-directed RNA polymerase complex",
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        "protein_name": "Protein unc-13 homolog A isoform X2",
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        "refseq_name": "protein unc-13 homolog A isoform X2",
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        "protein_names_refseq": "protein unc-13 homolog A isoform X2",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "length": 938,
        "protein_name": "Reverse transcriptase domain-containing protein",
        "gene_name": "LOC141379212",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
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        "gene_names_uniprotkb": "LOC141379212",
        "gene_names_refseq": "LOC141379212",
        "protein_names_uniprotkb": "Reverse transcriptase domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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    {
        "uniprot_canonical_ac": "A0AC58I1T2-1",
        "uniprot_id": "A0AC58I1T2_DANRE",
        "mass": 353197.0,
        "length": 3211,
        "protein_name": "Laminin subunit alpha-2 isoform X1",
        "gene_name": "lama2",
        "organism": "Zebrafish",
        "refseq_name": "laminin subunit alpha-2 isoform X1",
        "refseq_ac": "XP_073788193",
        "gene_names_uniprotkb": "lama2",
        "gene_names_refseq": "lama2",
        "protein_names_uniprotkb": "Laminin subunit alpha-2 isoform X1",
        "protein_names_refseq": "laminin subunit alpha-2 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Anti-angiogenic and anti-tumor peptide that inhibits endothelial cell migration, collagen-induced endothelial tube morphogenesis and blood vessel growth in the chorioallantoic membrane. Blocks endothelial cell adhesion to fibronectin and type I collagen. Anti-tumor agent in neovascularization. Interaction with its ligand, integrin alpha2/beta1, is required for the anti-angiogenic properties. Evokes a reduction in phosphorylation of receptor tyrosine kinases via alpha2/beta1 integrin-mediated activation of the tyrosine phosphatase, PTPN6., [UniProtKB, UniProtKB, UniProtKB]; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Has anti-angiogenic properties that require binding of calcium ions for full activity., [UniProtKB, UniProtKB, UniProtKB]",
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    {
        "uniprot_canonical_ac": "A0AC58I1W5-1",
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        "mass": 60786.0,
        "length": 585,
        "protein_name": "RNA-binding protein MEX3B",
        "gene_name": "LOC100331115",
        "organism": "Zebrafish",
        "refseq_name": "RNA-binding protein MEX3B",
        "refseq_ac": "NP_001429972",
        "gene_names_uniprotkb": "LOC100331115",
        "gene_names_refseq": "LOC100331115; mex3d",
        "protein_names_uniprotkb": "RNA-binding protein MEX3B",
        "protein_names_refseq": "RNA-binding protein MEX3B; RNA-binding protein MEX3D; mex-3 RNA binding family member D",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01005078.1, SRR26395015.1639612.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476733, SAMEA4476761 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1. On Sep 4, 2025 this sequence version replaced XP_073788230.1., [RefSeq]",
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        "uniprot_canonical_ac": "A0AC58I203-1",
        "uniprot_id": "A0AC58I203_DANRE",
        "mass": 42466.0,
        "length": 389,
        "protein_name": "Ankyrin repeat domain-containing protein 34B",
        "gene_name": "LOC110438154",
        "organism": "Zebrafish",
        "refseq_name": "ankyrin repeat domain-containing protein 34B",
        "refseq_ac": "XP_073788249",
        "gene_names_uniprotkb": "LOC110438154",
        "gene_names_refseq": "LOC110438154",
        "protein_names_uniprotkb": "Ankyrin repeat domain-containing protein 34B",
        "protein_names_refseq": "ankyrin repeat domain-containing protein 34B",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "length": 403,
        "protein_name": "Ena/VASP-like protein",
        "gene_name": "evlb",
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        "protein_names_uniprotkb": "Lethal(3)malignant brain tumor-like protein 3 isoform X1",
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        "go_molecular_function": "GO:0005509 calcium ion binding",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "tax_id": 7955,
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        "length": 475,
        "protein_name": "non-specific serine/threonine protein kinase",
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        "organism": "Zebrafish",
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        "refseq_ac": "NP_001108157",
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        "gene_names_refseq": "pimr132; si:dkey-197d18.2",
        "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1",
        "protein_names_refseq": "Pim proto-oncogene, serine/threonine kinase, related 132; novel potein similar to vertebrate PIM family oncogenes",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588722.40745275.1, SRR32588725.33807244.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN18715719 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1. On or before Jul 21, 2025 this sequence version replaced XP_073788828.1, NP_001108157.1., [RefSeq]",
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        "ec_number_list": "2.7.11.1;2.7.11.13;2.7.11.25;2.7.10.1;2.7.11.22;2.7.11.21;2.7.11.17;2.7.12.1;2.7.12.2;2.7.11.24;2.7.10.2;2.7.11.23;2.7.1.150;2.7.11.12;2.7.11.39;2.7.11.11;2.7.1.153;2.7.1.137;2.7.1.154;2.7.11.26;2.7.11.31",
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        "gene_names_refseq": "asap2b; fe36f09; si:dkey-81b15.3; wu:fe36f09; zgc:158353",
        "protein_names_uniprotkb": "Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2b isoform X1",
        "protein_names_refseq": "arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2b isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "HMG domain-containing protein",
        "gene_name": "LOC110438158",
        "organism": "Zebrafish",
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        "gene_names_uniprotkb": "LOC110438158",
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        "protein_name": "SGNH hydrolase-type esterase domain-containing protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "length": 499,
        "protein_name": "Cholesterol 24-hydroxylase",
        "gene_name": "cyp46a1.3",
        "organism": "Zebrafish",
        "refseq_name": "cytochrome P450 46A1.3 isoform X1",
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        "gene_names_refseq": "cyp46a1.3; zgc:136808",
        "protein_names_uniprotkb": "Cholesterol 24-hydroxylase; 1.14.14.25; Cholesterol 24-monooxygenase; Cholesterol 24S-hydroxylase; Cytochrome P450 46A1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; P450 monooxygenase that plays a major role in cholesterol homeostasis in the brain. Primarily catalyzes the hydroxylation (with S stereochemistry) at C-24 of cholesterol side chain, triggering cholesterol diffusion out of neurons and its further degradation. By promoting constant cholesterol elimination in neurons, may activate the mevalonate pathway and coordinate the synthesis of new cholesterol and nonsterol isoprenoids involved in synaptic activity and learning. Further hydroxylates cholesterol derivatives and hormone steroids on both the ring and side chain of these molecules, converting them into active oxysterols involved in lipid signaling and biosynthesis. Acts as an epoxidase converting cholesta-5,24-dien-3beta-ol/desmosterol into (24S),25-epoxycholesterol, an abundant lipid ligand of nuclear NR1H2 and NR1H3 receptors shown to promote neurogenesis in developing brain. May also catalyze the oxidative metabolism of xenobiotics, such as clotrimazole., [UniProtKB, UniProtKB]",
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        "protein_name": "Interactor protein for cytohesin exchange factors 1 isoform X1",
        "gene_name": "ipcef1",
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        "length": 336,
        "protein_name": "Trace amine-associated receptor 1",
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        "protein_name": "non-specific serine/threonine protein kinase",
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        "gene_names_refseq": "LOC137487771",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio                   :: 18% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "GO:0016301 kinase activity",
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        "record_id": "A0AC58I719-1",
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        "length": 1072,
        "protein_name": "Band 4.1-like protein 2 isoform X1",
        "gene_name": "wu:fi46h04",
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        "refseq_name": "band 4.1-like protein 2 isoform X1",
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        "protein_names_uniprotkb": "Band 4.1-like protein 2 isoform X1",
        "protein_names_refseq": "band 4.1-like protein 2 isoform X1",
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        "uniprot_id": "A0AC58I7A9_DANRE",
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        "length": 421,
        "protein_name": "A-kinase anchoring protein 7 isoform X1",
        "gene_name": "akap7",
        "organism": "Zebrafish",
        "refseq_name": "A-kinase anchoring protein 7 isoform X1",
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        "protein_names_uniprotkb": "A-kinase anchoring protein 7 isoform X1",
        "protein_names_refseq": "A-kinase anchoring protein 7 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "record_id": "A0AC58I7A9-1",
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        "length": 454,
        "protein_name": "Vesicular inhibitory amino acid transporter",
        "gene_name": "si:dkey-126h10.1",
        "organism": "Zebrafish",
        "refseq_name": "vesicular inhibitory amino acid transporter isoform X1",
        "refseq_ac": "XP_073790127",
        "gene_names_uniprotkb": "si:dkey-126h10.1",
        "gene_names_refseq": "si:dkey-126h10.1",
        "protein_names_uniprotkb": "Vesicular inhibitory amino acid transporter; Solute carrier family 32 member 1; Vesicular GABA transporter",
        "protein_names_refseq": "vesicular inhibitory amino acid transporter isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Antiporter that exchanges vesicular protons for cytosolic 4-aminobutanoate or to a lesser extend glycine, thus allowing their secretion from nerve terminals. The transport is equally dependent on the chemical and electrical components of the proton gradient. May also transport beta-alanine. Acidification of GABAergic synaptic vesicles is a prerequisite for 4-aminobutanoate uptake., [UniProtKB, UniProtKB, UniProtKB]",
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    {
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        "length": 1163,
        "protein_name": "Nidogen-2 isoform X1",
        "gene_name": "nid2b",
        "organism": "Zebrafish",
        "refseq_name": "nidogen-2 isoform X1",
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        "gene_names_uniprotkb": "nid2b",
        "gene_names_refseq": "nid2b",
        "protein_names_uniprotkb": "Nidogen-2 isoform X1",
        "protein_names_refseq": "nidogen-2 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Male-specific lethal 1-like 1 isoform X1",
        "gene_name": "msl1a",
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        "length": 388,
        "protein_name": "Uncharacterized protein isoform X2",
        "gene_name": "zgc:174623",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X2",
        "refseq_ac": "XP_073790250",
        "gene_names_uniprotkb": "zgc:174623; zgc:174623",
        "gene_names_refseq": "zgc:174623",
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        "protein_names_refseq": "uncharacterized protein isoform X2",
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        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific",
        "go_cellular_component": "GO:0005634 nucleus",
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        "protein_name": "Thromboxane A2 receptor",
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        "length": 377,
        "protein_name": "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase",
        "gene_name": "st6galnac2",
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        "length": 1762,
        "protein_name": "Protein Shroom3 isoform X1",
        "gene_name": "shroom3",
        "organism": "Zebrafish",
        "refseq_name": "protein Shroom3 isoform X1",
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        "gene_names_uniprotkb": "shroom3; Shr3v1; Shr3v2; Shroom3v1; Shroom3v2",
        "gene_names_refseq": "Shr3v1; Shr3v2; Shroom3v1; Shroom3v2; shroom3",
        "protein_names_uniprotkb": "Protein Shroom3 isoform X1",
        "protein_names_refseq": "protein Shroom3 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "",
        "go_cellular_component": "",
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        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58I7X0-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58I891-1",
        "uniprot_id": "A0AC58I891_DANRE",
        "mass": 101953.0,
        "length": 905,
        "protein_name": "Complement component C6 isoform X1",
        "gene_name": "c6.2",
        "organism": "Zebrafish",
        "refseq_name": "complement component C6 precursor",
        "refseq_ac": "NP_956932",
        "gene_names_uniprotkb": "c6.2; c6; si:ch211-22d5.4; zgc:64073",
        "gene_names_refseq": "c6.2; c6; si:ch211-22d5.4; zgc:64073",
        "protein_names_uniprotkb": "Complement component C6 isoform X1",
        "protein_names_refseq": "complement component 6; complement component C6 precursor",
        "tax_id": 7955,
        "disease": "",
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        "pathway_count": 0,
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        "publication_id_list": "",
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        "function": "##Evidence-Data-START## Transcript exon combination :: BC057429.1, SRR32588729.15151578.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On Jun 25, 2025 this sequence version replaced NP_956932.2. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "missing_score": 10000,
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        "synthesized_glycan_count": 0,
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        "record_id": "A0AC58I891-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58I876-1",
        "uniprot_id": "A0AC58I876_DANRE",
        "mass": 56928.0,
        "length": 509,
        "protein_name": "Lymphocyte cytosolic protein 2",
        "gene_name": "lcp2a",
        "organism": "Zebrafish",
        "refseq_name": "lymphocyte cytosolic protein 2a isoform X1",
        "refseq_ac": "XP_073790427",
        "gene_names_uniprotkb": "lcp2a; wu:fj47a12; zgc:101809",
        "gene_names_refseq": "lcp2a; wu:fj47a12; zgc:101809",
        "protein_names_uniprotkb": "Lymphocyte cytosolic protein 2; SH2 domain-containing leukocyte protein of 76 kDa; SLP-76 tyrosine phosphoprotein",
        "protein_names_refseq": "lymphocyte cytosolic protein 2a isoform X1",
        "tax_id": 7955,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Adapter protein primarily involved in signaling pathways within T-cells, as well as other immune cells such as platelets, mast cells, and natural killer (NK) cells. Plays a crucial role for transducing signal from the T-cell receptor (TCR) after antigen recognition leading to T-cell activation. Mechanistically, once phosphorylated by the kinase ZAP70, mediates interactions with the guanine-nucleotide exchange factor VAV1, the adapter protein NCK and the kinase ITK. In turn, stimulates the activation of PKC-theta/PRKCQ and NF-kappa-B transcriptional activity in response to CD3 and CD28 costimulation. Also plays an essential role in AGER-induced signaling pathways including p38 MAPK and ERK1/2 activation leading to cytokine release and pro-inflammatory responses., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
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    {
        "uniprot_canonical_ac": "A0AC58I8A6-1",
        "uniprot_id": "A0AC58I8A6_DANRE",
        "mass": 107253.0,
        "length": 947,
        "protein_name": "protein kinase C",
        "gene_name": "pkn1b",
        "organism": "Zebrafish",
        "refseq_name": "serine/threonine-protein kinase N1b isoform X1",
        "refseq_ac": "XP_073790458",
        "gene_names_uniprotkb": "pkn1b; zgc:162290",
        "gene_names_refseq": "pkn1b; zgc:162290",
        "protein_names_uniprotkb": "protein kinase C; 2.7.11.13",
        "protein_names_refseq": "serine/threonine-protein kinase N1b isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "ec_number_list": "2.7.11.1;2.7.11.13;2.7.11.25;2.7.10.1;2.7.11.22;2.7.11.21;2.7.11.17;2.7.12.1;2.7.12.2;2.7.11.24;2.7.10.2;2.7.11.23;2.7.1.150;2.7.11.12;2.7.11.39;2.7.11.11;2.7.1.153;2.7.1.137;2.7.1.154;2.7.11.26;2.7.11.31",
        "go_molecular_function": "GO:0016301 kinase activity",
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    {
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        "uniprot_id": "A0AC58I8M6_DANRE",
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        "length": 285,
        "protein_name": "Deoxycytidine kinase isoform X1",
        "gene_name": "dck",
        "organism": "Zebrafish",
        "refseq_name": "deoxycytidine kinase isoform X1",
        "refseq_ac": "XP_073790587",
        "gene_names_uniprotkb": "dck; wu:fc15f06; zgc:101771",
        "gene_names_refseq": "dck; wu:fc15f06; zgc:101771",
        "protein_names_uniprotkb": "Deoxycytidine kinase isoform X1",
        "protein_names_refseq": "deoxycytidine kinase isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "ec_number_list": "2.7.1.113",
        "go_molecular_function": "GO:0016301 kinase activity",
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    {
        "uniprot_canonical_ac": "A0AC58I8R3-1",
        "uniprot_id": "A0AC58I8R3_DANRE",
        "mass": 42290.0,
        "length": 373,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "si:rp71-1h20.5",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073790613",
        "gene_names_uniprotkb": "si:rp71-1h20.5; bZ1H20.5; fj37h12; wu:fj37h12; zgc:113122",
        "gene_names_refseq": "bZ1H20.5; fj37h12; si:rp71-1h20.5; wu:fj37h12; zgc:113122",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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    {
        "uniprot_canonical_ac": "A0AC58I8S8-1",
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        "mass": 35184.0,
        "length": 320,
        "protein_name": "WD repeat-containing protein 38 isoform X1",
        "gene_name": "wdr38",
        "organism": "Zebrafish",
        "refseq_name": "WD repeat-containing protein 38 isoform 1",
        "refseq_ac": "NP_001429115",
        "gene_names_uniprotkb": "wdr38; zgc:112026",
        "gene_names_refseq": "wdr38; zgc:112026",
        "protein_names_uniprotkb": "WD repeat-containing protein 38 isoform X1",
        "protein_names_refseq": "WD repeat-containing protein 38 isoform 1",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588721.939825.1, SRR32588723.1477074.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705, SAMN06350654 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On Jul 29, 2025 this sequence version replaced XP_073790630.1., [RefSeq]",
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    {
        "uniprot_canonical_ac": "A0AC58I937-1",
        "uniprot_id": "A0AC58I937_DANRE",
        "mass": 43365.0,
        "length": 376,
        "protein_name": "Interleukin 21 receptor, tandem duplicate 2 isoform X1",
        "gene_name": "il21r.2",
        "organism": "Zebrafish",
        "refseq_name": "interleukin 21 receptor, tandem duplicate 2 precursor",
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        "gene_names_uniprotkb": "il21r.2; il-21r.b; il21rl",
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        "length": 631,
        "protein_name": "Multidrug and toxin extrusion protein",
        "gene_name": "slc47a2.2",
        "organism": "Zebrafish",
        "refseq_name": "solute carrier family 47 member 2, tandem duplicate 2 isoform X1",
        "refseq_ac": "XP_073790879",
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        "gene_names_refseq": "mate4; slc47a2.2",
        "protein_names_uniprotkb": "Multidrug and toxin extrusion protein",
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        "protein_name": "RNA helicase",
        "gene_name": "dhx58",
        "organism": "Zebrafish",
        "refseq_name": "ATP-dependent RNA helicase DHX58 isoform X1",
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        "gene_names_uniprotkb": "dhx58",
        "gene_names_refseq": "dhx58",
        "protein_names_uniprotkb": "RNA helicase; 3.6.4.13",
        "protein_names_refseq": "ATP-dependent RNA helicase DHX58 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "ec_number_list": "2.3.2.-;2.3.2.27;3.6.4.-;4.2.99.18;5.6.2.4;5.6.2.3;3.6.4.12;3.6.4.13;2.7.4.3;7.6.2.2;5.6.1.6;7.6.2.3;3.6.1.5;3.6.4.6;3.6.1.15;3.6.4.10;5.6.2.-;2.7.7.7;2.7.7.49;5.6.2.5;3.6.5.-;3.6.1.-",
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        "protein_name": "Vimentin isoform X1",
        "gene_name": "LOC572200",
        "organism": "Zebrafish",
        "refseq_name": "vimentin isoform X1",
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        "gene_names_uniprotkb": "LOC572200",
        "gene_names_refseq": "LOC572200",
        "protein_names_uniprotkb": "Vimentin isoform X1",
        "protein_names_refseq": "vimentin isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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    {
        "uniprot_canonical_ac": "A0AC58IA14-1",
        "uniprot_id": "A0AC58IA14_DANRE",
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        "length": 595,
        "protein_name": "Polypeptide N-acetylgalactosaminyltransferase",
        "gene_name": "galnt10",
        "organism": "Zebrafish",
        "refseq_name": "polypeptide N-acetylgalactosaminyltransferase 10",
        "refseq_ac": "NP_001428848",
        "gene_names_uniprotkb": "galnt10; wu:fb37e08; zgc:153114",
        "gene_names_refseq": "galnt10; wu:fb37e08; zgc:153114",
        "protein_names_uniprotkb": "Polypeptide N-acetylgalactosaminyltransferase; 2.4.1.-; Protein-UDP acetylgalactosaminyltransferase",
        "protein_names_refseq": "polypeptide N-acetylgalactosaminyltransferase 10",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01011153.1, MN850438.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505372, SAMEA3505375 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On Jul 10, 2025 this sequence version replaced XP_073791083.1., [RefSeq]; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward Muc5Ac and EA2 peptide substrates., [UniProtKB, UniProtKB]",
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        "secondary_ac_list": "A0AC58IA19;A0AC58IA28;A0AC58IA32;A0AC58IA46;A0AC58IA52",
        "ec_number_list": "2.4.1.-",
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        "record_id": "A0AC58IA14-1",
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    {
        "uniprot_canonical_ac": "A0AC58IA45-1",
        "uniprot_id": "A0AC58IA45_DANRE",
        "mass": 108443.0,
        "length": 966,
        "protein_name": "Glutamate receptor",
        "gene_name": "grin1a",
        "organism": "Zebrafish",
        "refseq_name": "glutamate receptor ionotropic, NMDA 1a isoform X1",
        "refseq_ac": "XP_073791110",
        "gene_names_uniprotkb": "grin1a; NMDAR1.1; zgc:152678",
        "gene_names_refseq": "NMDAR1.1; grin1a; zgc:152678",
        "protein_names_uniprotkb": "Glutamate receptor",
        "protein_names_refseq": "glutamate receptor ionotropic, NMDA 1a isoform X1",
        "tax_id": 7955,
        "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041); autosomal dominant neurodevelopmental disorder with or without hyperkinetic movements and seizures (Disease Ontology:DOID:0070038); developmental and epileptic encephalopathy 101 (Disease Ontology:DOID:0070387); Alzheimer's disease (Disease Ontology:DOID:10652); opioid abuse (Disease Ontology:DOID:11206); sciatic neuropathy (Disease Ontology:DOID:11446); neurodegenerative disease (Disease Ontology:DOID:1289); cognitive disorder (Disease Ontology:DOID:1561); alcohol use disorder (Disease Ontology:DOID:1574); status epilepticus (Disease Ontology:DOID:1824); middle cerebral artery infarction (Disease Ontology:DOID:3525); cerebral infarction (Disease Ontology:DOID:3526); placental insufficiency (Disease Ontology:DOID:3891); schizophrenia (Disease Ontology:DOID:5419); vascular dementia (Disease Ontology:DOID:8725)",
        "pathway": " (dre:767745)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "16123982;17258920;18715895;19005681;19500364;36637428;37114543;38336823;38598053;39199302",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "ec_number_list": "2.7.11.1;1.5.1.2",
        "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity;GO:0046872 metal ion binding;GO:0004972 NMDA glutamate receptor activity",
        "go_cellular_component": "GO:0017146 NMDA selective glutamate receptor complex;GO:0098839 postsynaptic density membrane",
        "go_biological_process": "GO:0070588 calcium ion transmembrane transport",
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    {
        "uniprot_canonical_ac": "A0AC58IB39-1",
        "uniprot_id": "A0AC58IB39_DANRE",
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        "length": 494,
        "protein_name": "5-hydroxytryptamine receptor 3A",
        "gene_name": "htr3a",
        "organism": "Zebrafish",
        "refseq_name": "5-hydroxytryptamine receptor 3A isoform X1",
        "refseq_ac": "XP_073791438",
        "gene_names_uniprotkb": "htr3a",
        "gene_names_refseq": "htr3a",
        "protein_names_uniprotkb": "5-hydroxytryptamine receptor 3A; 5-hydroxytryptamine receptor 3; Serotonin receptor 3A; Serotonin-gated ion channel receptor",
        "protein_names_refseq": "5-hydroxytryptamine receptor 3A isoform X1",
        "tax_id": 7955,
        "disease": "alcohol dependence (Disease Ontology:DOID:0050741); nicotine dependence (Disease Ontology:DOID:0050742); irritable bowel syndrome (Disease Ontology:DOID:9778); cocaine dependence (Disease Ontology:DOID:9975); heroin dependence (Disease Ontology:DOID:9976)",
        "pathway": " (dre:571641)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0005886 plasma membrane;GO:0045202 synapse;GO:0045211 postsynaptic membrane;GO:0043005 neuron projection;GO:1902495 transmembrane transporter complex",
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        "protein_name": "Unconventional myosin-VIIa isoform X1",
        "gene_name": "myo7ab",
        "organism": "Zebrafish",
        "refseq_name": "unconventional myosin-VIIa isoform X1",
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        "gene_names_uniprotkb": "myo7ab",
        "gene_names_refseq": "myo7ab",
        "protein_names_uniprotkb": "Unconventional myosin-VIIa isoform X1",
        "protein_names_refseq": "unconventional myosin-VIIa isoform X1",
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        "disease": "Usher syndrome type 1B (Disease Ontology:DOID:0070655); autosomal recessive nonsyndromic deafness 2 (Disease Ontology:DOID:0110477); autosomal dominant nonsyndromic deafness 11 (Disease Ontology:DOID:0110543); Usher syndrome type 1 (Disease Ontology:DOID:0110826); sensorineural hearing loss (Disease Ontology:DOID:10003); Leber congenital amaurosis (Disease Ontology:DOID:14791); auditory system disease (Disease Ontology:DOID:2742); congenital nystagmus (Disease Ontology:DOID:9649)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "GO:0003779 actin binding;GO:0005524 ATP binding;GO:0003774 cytoskeletal motor activity",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0045177 apical part of cell;GO:0005902 microvillus;GO:0016459 myosin complex",
        "go_biological_process": "GO:0009887 animal organ morphogenesis;GO:0030182 neuron differentiation;GO:0007605 sensory perception of sound;GO:0007423 sensory organ development",
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        "length": 1484,
        "protein_name": "RIMS-binding protein 2",
        "gene_name": "rimbp2a",
        "organism": "Zebrafish",
        "refseq_name": "RIMS-binding protein 2 isoform X1",
        "refseq_ac": "XP_073791235",
        "gene_names_uniprotkb": "rimbp2a",
        "gene_names_refseq": "rimbp2a",
        "protein_names_uniprotkb": "RIMS-binding protein 2",
        "protein_names_refseq": "RIMS-binding protein 2 isoform X1",
        "tax_id": 7955,
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        "pathway": " (dre:100535071)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays a role in the synaptic transmission as bifunctional linker that interacts simultaneously with RIMS1, RIMS2, CACNA1D and CACNA1B., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "uniprot_canonical_ac": "A0AC58ICB1-1",
        "uniprot_id": "A0AC58ICB1_DANRE",
        "mass": 123642.0,
        "length": 1116,
        "protein_name": "AP-3 complex subunit beta",
        "gene_name": "ap3b1a",
        "organism": "Zebrafish",
        "refseq_name": "AP-3 complex subunit beta-1 isoform X1",
        "refseq_ac": "XP_073791871",
        "gene_names_uniprotkb": "ap3b1a",
        "gene_names_refseq": "ap3b1a",
        "protein_names_uniprotkb": "AP-3 complex subunit beta",
        "protein_names_refseq": "AP-3 complex subunit beta-1 isoform X1",
        "tax_id": 7955,
        "disease": "Hermansky-Pudlak syndrome 2 (Disease Ontology:DOID:0060540); neutropenia (Disease Ontology:DOID:1227); platelet storage pool deficiency (Disease Ontology:DOID:2223); interstitial lung disease (Disease Ontology:DOID:3082); Hermansky-Pudlak syndrome (Disease Ontology:DOID:3753); pulmonary fibrosis (Disease Ontology:DOID:3770)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0030665 clathrin-coated vesicle membrane;GO:0030123 AP-3 adaptor complex;GO:0030131 clathrin adaptor complex;GO:1904115 axon cytoplasm",
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        "protein_name": "Potassium channel subfamily T member 1 isoform X1",
        "gene_name": "kcnt1a",
        "organism": "Zebrafish",
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        "gene_names_uniprotkb": "kcnt1a",
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        "protein_names_uniprotkb": "Potassium channel subfamily T member 1 isoform X1",
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        "tax_id": 7955,
        "disease": "autosomal dominant nocturnal frontal lobe epilepsy 5 (Disease Ontology:DOID:0060686); developmental and epileptic encephalopathy 14 (Disease Ontology:DOID:0080439); epilepsy (Disease Ontology:DOID:1826)",
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        "gene_name": "LOC101883468",
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        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "GO:0005525 GTP binding",
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    {
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        "protein_name": "Glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X1",
        "gene_name": "gdpd4b",
        "organism": "Zebrafish",
        "refseq_name": "glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X1",
        "refseq_ac": "XP_073791432",
        "gene_names_uniprotkb": "gdpd4b",
        "gene_names_refseq": "gdpd4b",
        "protein_names_uniprotkb": "Glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X1",
        "protein_names_refseq": "glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "exo-alpha-sialidase",
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        "gene_names_refseq": "im:7158396; neu3.1; zgc:158400",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_names_refseq": "rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta isoform X1",
        "tax_id": 7955,
        "disease": "retinitis pigmentosa 40 (Disease Ontology:DOID:0110375); congenital stationary night blindness autosomal dominant 2 (Disease Ontology:DOID:0110863); retinitis pigmentosa (Disease Ontology:DOID:10584); retinal degeneration (Disease Ontology:DOID:8466)",
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        "ec_number_list": "3.1.4.-",
        "go_molecular_function": "GO:0046872 metal ion binding;GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity;GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity",
        "go_cellular_component": "GO:0042622 photoreceptor outer segment membrane",
        "go_biological_process": "GO:0007165 signal transduction;GO:0007601 visual perception;GO:0060041 retina development in camera-type eye;GO:0141162 negative regulation of cAMP/PKA signal transduction",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IAR7-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IC42-1",
        "uniprot_id": "A0AC58IC42_DANRE",
        "mass": 35819.0,
        "length": 311,
        "protein_name": "Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform X1",
        "gene_name": "st6galnac6",
        "organism": "Zebrafish",
        "refseq_name": "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform 1",
        "refseq_ac": "NP_001429431",
        "gene_names_uniprotkb": "st6galnac6",
        "gene_names_refseq": "siat7F; st6galnac6",
        "protein_names_uniprotkb": "Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform X1",
        "protein_names_refseq": "alpha-2,6-sialyltransferase ST6GalNAc VI; alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform 1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:407715)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588719.3357303.1, SRR32588730.9829117.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505392, SAMEA4476742 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On Aug 11, 2025 this sequence version replaced XP_073791802.1., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "ec_number_list": "",
        "go_molecular_function": "GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",
        "go_cellular_component": "GO:0000139 Golgi membrane",
        "go_biological_process": "GO:0009101 glycoprotein biosynthetic process;GO:0009311 oligosaccharide metabolic process;GO:0001574 ganglioside biosynthetic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IC42-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58ICR3-1",
        "uniprot_id": "A0AC58ICR3_DANRE",
        "mass": 56002.0,
        "length": 497,
        "protein_name": "Potassium channel subfamily K member 4 isoform X1",
        "gene_name": "kcnk4b",
        "organism": "Zebrafish",
        "refseq_name": "potassium channel subfamily K member 4 isoform X1",
        "refseq_ac": "XP_073792034",
        "gene_names_uniprotkb": "kcnk4b",
        "gene_names_refseq": "kcnk4b",
        "protein_names_uniprotkb": "Potassium channel subfamily K member 4 isoform X1",
        "protein_names_refseq": "potassium channel subfamily K member 4 isoform X1",
        "tax_id": 7955,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "secondary_ac_list": "A0AC58ICR7",
        "ec_number_list": "2.7.11.1;1.5.1.2",
        "go_molecular_function": "GO:0015271 outward rectifier potassium channel activity;GO:0022841 potassium ion leak channel activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0034220 monoatomic ion transmembrane transport;GO:0071805 potassium ion transmembrane transport",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58ICR3-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58ICB9-1",
        "uniprot_id": "A0AC58ICB9_DANRE",
        "mass": 61242.0,
        "length": 544,
        "protein_name": "Proteinase-activated receptor 1",
        "gene_name": "LOC100149161",
        "organism": "Zebrafish",
        "refseq_name": "proteinase-activated receptor 1-like isoform X2",
        "refseq_ac": "XP_073791874",
        "gene_names_uniprotkb": "LOC100149161",
        "gene_names_refseq": "LOC100149161",
        "protein_names_uniprotkb": "Proteinase-activated receptor 1; Thrombin receptor",
        "protein_names_refseq": "proteinase-activated receptor 1-like isoform X2",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100149161)",
        "pathway_count": 1,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "GO:0015057 thrombin-activated receptor activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0007596 blood coagulation;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0030194 positive regulation of blood coagulation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58ICB9-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IB15-1",
        "uniprot_id": "A0AC58IB15_DANRE",
        "mass": 97288.0,
        "length": 837,
        "protein_name": "Cullin-5",
        "gene_name": "cul5b",
        "organism": "Zebrafish",
        "refseq_name": "cullin-5 isoform X1",
        "refseq_ac": "XP_073791420",
        "gene_names_uniprotkb": "cul5b",
        "gene_names_refseq": "cul5b",
        "protein_names_uniprotkb": "Cullin-5",
        "protein_names_refseq": "cullin-5 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100006147)",
        "pathway_count": 1,
        "publication_count": 1,
        "publication_id_list": "40044042",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "total_reported_n_glycosites": 0,
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        "glycan_count": 1,
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        "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0031461 cullin-RING ubiquitin ligase complex",
        "go_biological_process": "GO:0007165 signal transduction;GO:0016567 protein ubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.4,
        "record_id": "A0AC58IB15-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IC79-1",
        "uniprot_id": "A0AC58IC79_DANRE",
        "mass": 41714.0,
        "length": 370,
        "protein_name": "Hexosyltransferase",
        "gene_name": "b3galt9",
        "organism": "Zebrafish",
        "refseq_name": "beta-1,3-galactosyltransferase 9 isoform X2",
        "refseq_ac": "XP_005161047",
        "gene_names_uniprotkb": "b3galt9",
        "gene_names_refseq": "b3galt9",
        "protein_names_uniprotkb": "Hexosyltransferase; 2.4.1.-",
        "protein_names_refseq": "beta-1,3-galactosyltransferase 9 isoform X2",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:101883349)",
        "pathway_count": 1,
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        "publication_id_list": "",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_005161047.1. COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "ec_number_list": "",
        "go_molecular_function": "GO:0016757 glycosyltransferase activity;GO:0016758 hexosyltransferase activity",
        "go_cellular_component": "GO:0000139 Golgi membrane",
        "go_biological_process": "GO:0009101 glycoprotein biosynthetic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IC79-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IAF3-1",
        "uniprot_id": "A0AC58IAF3_DANRE",
        "mass": 103669.0,
        "length": 968,
        "protein_name": "Whirlin",
        "gene_name": "whrna",
        "organism": "Zebrafish",
        "refseq_name": "whirlin isoform X1",
        "refseq_ac": "XP_073791192",
        "gene_names_uniprotkb": "whrna",
        "gene_names_refseq": "whrna",
        "protein_names_uniprotkb": "Whirlin",
        "protein_names_refseq": "whirlin isoform X1",
        "tax_id": 7955,
        "disease": "autosomal recessive nonsyndromic deafness 31 (Disease Ontology:DOID:0110490); Usher syndrome type 2D (Disease Ontology:DOID:0110840); sensorineural hearing loss (Disease Ontology:DOID:10003)",
        "pathway": " (dre:100334777)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in hearing and vision as member of the USH2 complex. Necessary for elongation and maintenance of inner and outer hair cell stereocilia in the organ of Corti in the inner ear. Involved in the maintenance of the hair bundle ankle region, which connects stereocilia in cochlear hair cells of the inner ear. In retina photoreceptors, required for the maintenance of periciliary membrane complex that seems to play a role in regulating intracellular protein transport., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
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        "missing_score": 10000,
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        "secondary_ac_list": "",
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        "go_molecular_function": "",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005929 cilium;GO:0030426 growth cone;GO:0045202 synapse",
        "go_biological_process": "GO:0007605 sensory perception of sound;GO:0060088 auditory receptor cell stereocilium organization",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IAF3-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IC96-1",
        "uniprot_id": "A0AC58IC96_DANRE",
        "mass": 90734.0,
        "length": 838,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC110438007",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073791842",
        "gene_names_uniprotkb": "LOC110438007",
        "gene_names_refseq": "LOC110438007",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
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        "pathway": " (dre:110438007)",
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        "protein_name": "exo-alpha-sialidase",
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        "go_biological_process": "GO:0016042 lipid catabolic process",
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        "protein_name": "Syncytin-A-like",
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        "protein_name": "Chemokine XC receptor 1-like",
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        "protein_name": "calcium/calmodulin-dependent protein kinase",
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        "ec_number_list": "2.7.11.1;2.7.11.13;2.7.11.25;2.7.10.1;2.7.11.22;2.7.11.21;2.7.11.17;2.7.12.1;2.7.12.2;2.7.11.24;2.7.10.2;2.7.11.23;2.7.1.150;2.7.11.12;2.7.11.39;2.7.11.11;2.7.1.153;2.7.1.137;2.7.1.154;2.7.11.26;2.7.11.31",
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        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
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        "pathway": "",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IAF6-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IAG5-1",
        "uniprot_id": "A0AC58IAG5_DANRE",
        "mass": 32833.0,
        "length": 291,
        "protein_name": "Lysosomal membrane ascorbate-dependent ferrireductase CYB561A3",
        "gene_name": "cyb561a3b",
        "organism": "Zebrafish",
        "refseq_name": "lysosomal membrane ascorbate-dependent ferrireductase CYB561A3-like isoform X1",
        "refseq_ac": "XP_073791228",
        "gene_names_uniprotkb": "cyb561a3b",
        "gene_names_refseq": "cyb561a3b",
        "protein_names_uniprotkb": "Lysosomal membrane ascorbate-dependent ferrireductase CYB561A3; 7.2.1.3; Cytochrome b ascorbate-dependent protein 3; Lysosomal cytochrome b",
        "protein_names_refseq": "lysosomal membrane ascorbate-dependent ferrireductase CYB561A3-like isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Transmembrane reductase that uses ascorbate as an electron donor in the cytoplasm and transfers electrons across membranes to reduce iron cations Fe(3+) into Fe(2+) in the lumen of the late endosome and lysosome. Reduced iron can then be extruded from the late endosome and lysosome to the cytoplasm by divalent metal-specific transporters. It is therefore most probably involved in endosomal and lysosomal cellular iron homeostasis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "secondary_ac_list": "",
        "ec_number_list": "7.2.1.3",
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        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IAG5-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IAM6-1",
        "uniprot_id": "A0AC58IAM6_DANRE",
        "mass": 66127.0,
        "length": 583,
        "protein_name": "Dynein axonemal intermediate chain 1 isoform X1",
        "gene_name": "dnai1.1",
        "organism": "Zebrafish",
        "refseq_name": "dynein axonemal intermediate chain 1 isoform X1",
        "refseq_ac": "XP_073791280",
        "gene_names_uniprotkb": "dnai1.1",
        "gene_names_refseq": "dnai1.1",
        "protein_names_uniprotkb": "Dynein axonemal intermediate chain 1 isoform X1",
        "protein_names_refseq": "dynein axonemal intermediate chain 1 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IAM6-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IAQ2-1",
        "uniprot_id": "A0AC58IAQ2_DANRE",
        "mass": 68240.0,
        "length": 604,
        "protein_name": "MAGUK p55 subfamily member 4-like isoform X1",
        "gene_name": "LOC556594",
        "organism": "Zebrafish",
        "refseq_name": "MAGUK p55 subfamily member 4-like isoform X1",
        "refseq_ac": "XP_073791303",
        "gene_names_uniprotkb": "LOC556594",
        "gene_names_refseq": "LOC556594",
        "protein_names_uniprotkb": "MAGUK p55 subfamily member 4-like isoform X1",
        "protein_names_refseq": "MAGUK p55 subfamily member 4-like isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "record_id": "A0AC58IAQ2-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58IAT1-1",
        "uniprot_id": "A0AC58IAT1_DANRE",
        "mass": 77892.0,
        "length": 704,
        "protein_name": "Amino acid transporter",
        "gene_name": "slc1a9",
        "organism": "Zebrafish",
        "refseq_name": "solute carrier family 1 member 9 isoform X1",
        "refseq_ac": "XP_073791347",
        "gene_names_uniprotkb": "slc1a9",
        "gene_names_refseq": "slc1a9",
        "protein_names_uniprotkb": "Amino acid transporter",
        "protein_names_refseq": "solute carrier family 1 member 9 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "hit_score": 0.1,
        "record_id": "A0AC58IAT1-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IAW7-1",
        "uniprot_id": "A0AC58IAW7_DANRE",
        "mass": 93811.0,
        "length": 833,
        "protein_name": "Complement component C7",
        "gene_name": "LOC141379850",
        "organism": "Zebrafish",
        "refseq_name": "complement component C7-like",
        "refseq_ac": "XP_073791378",
        "gene_names_uniprotkb": "LOC141379850",
        "gene_names_refseq": "LOC141379850",
        "protein_names_uniprotkb": "Complement component C7",
        "protein_names_refseq": "complement component C7-like",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the membrane attack complex (MAC), a multiprotein complex activated by the complement cascade, which inserts into a target cell membrane and forms a pore, leading to target cell membrane rupture and cell lysis. The MAC is initiated by proteolytic cleavage of C5 into complement C5b in response to the classical, alternative, lectin and GZMK complement pathways. The complement pathways consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. C7 serves as a membrane anchor. During MAC assembly, associates with C5b and C6 to form the C5b-7 complex, a key lipophilic precursor of the MAC complex, which associates with the outer leaflet and reduces the energy for membrane bending., [UniProtKB, UniProtKB]",
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    {
        "uniprot_canonical_ac": "A0AC58IAY6-1",
        "uniprot_id": "A0AC58IAY6_DANRE",
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        "length": 633,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC101882370",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073791387",
        "gene_names_uniprotkb": "LOC101882370",
        "gene_names_refseq": "LOC101882370",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "gene_name": "LOC141379869",
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        "gene_names_uniprotkb": "LOC141379890",
        "gene_names_refseq": "LOC141379890",
        "protein_names_uniprotkb": "SGNH hydrolase-type esterase domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
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        "pathway": "",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "missing_score": 10000,
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        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IBE7-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IBG4-1",
        "uniprot_id": "A0AC58IBG4_DANRE",
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        "length": 376,
        "protein_name": "Glucose-dependent insulinotropic receptor",
        "gene_name": "gpr119",
        "organism": "Zebrafish",
        "refseq_name": "glucose-dependent insulinotropic receptor",
        "refseq_ac": "XP_021329117",
        "gene_names_uniprotkb": "gpr119",
        "gene_names_refseq": "gpr119",
        "protein_names_uniprotkb": "Glucose-dependent insulinotropic receptor",
        "protein_names_refseq": "glucose-dependent insulinotropic receptor",
        "tax_id": 7955,
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        "pathway": " (dre:100001479)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "secondary_ac_list": "A0A8M1PUJ3",
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        "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0031210 phosphatidylcholine binding",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane",
        "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway",
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        "record_id": "A0AC58IBG4-1",
        "record_type": "protein"
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        "uniprot_canonical_ac": "A0AC58IBG6-1",
        "uniprot_id": "A0AC58IBG6_DANRE",
        "mass": 61182.0,
        "length": 533,
        "protein_name": "Neuronal acetylcholine receptor subunit alpha-10 isoform X1",
        "gene_name": "LOC101882637",
        "organism": "Zebrafish",
        "refseq_name": "neuronal acetylcholine receptor subunit alpha-10 isoform X1",
        "refseq_ac": "XP_073791579",
        "gene_names_uniprotkb": "LOC101882637",
        "gene_names_refseq": "LOC101882637",
        "protein_names_uniprotkb": "Neuronal acetylcholine receptor subunit alpha-10 isoform X1",
        "protein_names_refseq": "neuronal acetylcholine receptor subunit alpha-10 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "",
        "ec_number_list": "2.7.11.1;1.5.1.2",
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IBG6-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58IBG7-1",
        "uniprot_id": "A0AC58IBG7_DANRE",
        "mass": 134058.0,
        "length": 1176,
        "protein_name": "Leucine--tRNA ligase, cytoplasmic",
        "gene_name": "lars1b",
        "organism": "Zebrafish",
        "refseq_name": "leucine--tRNA ligase, cytoplasmic",
        "refseq_ac": "XP_073791581",
        "gene_names_uniprotkb": "lars1b",
        "gene_names_refseq": "lars1b",
        "protein_names_uniprotkb": "Leucine--tRNA ligase, cytoplasmic; 6.1.1.4; Leucyl-tRNA synthetase",
        "protein_names_refseq": "leucine--tRNA ligase, cytoplasmic",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Aminoacyl-tRNA synthetase that catalyzes the specific attachment of leucine to its cognate tRNA (tRNA(Leu)). It performs tRNA aminoacylation in a two-step reaction: Leu is initially activated by ATP to form a leucyl-adenylate (Leu-AMP) intermediate; then the leucyl moiety is transferred to the acceptor 3' end of the tRNA to yield leucyl-tRNA. To improve the fidelity of catalytic reactions, it is also able to hydrolyze misactivated aminoacyl-adenylate intermediates (pre-transfer editing) and mischarged aminoacyl-tRNAs (post-transfer editing)., [UniProtKB, UniProtKB]",
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        "missing_score": 10000,
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        "secondary_ac_list": "",
        "ec_number_list": "6.1.1.4",
        "go_molecular_function": "GO:0016874 ligase activity",
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    {
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        "uniprot_id": "A0AC58IBH7_DANRE",
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        "length": 285,
        "protein_name": "Protein PIMREG",
        "gene_name": "pimreg",
        "organism": "Zebrafish",
        "refseq_name": "protein PIMREG",
        "refseq_ac": "XP_073791577",
        "gene_names_uniprotkb": "pimreg",
        "gene_names_refseq": "pimreg",
        "protein_names_uniprotkb": "Protein PIMREG",
        "protein_names_refseq": "protein PIMREG",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "uniprot_id": "A0AC58IBJ9_DANRE",
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        "length": 523,
        "protein_name": "Gamma-aminobutyric acid receptor subunit beta-2",
        "gene_name": "gabrb2b",
        "organism": "Zebrafish",
        "refseq_name": "gamma-aminobutyric acid receptor subunit beta-2 isoform X1",
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        "gene_names_uniprotkb": "gabrb2b",
        "gene_names_refseq": "gabrb2b",
        "protein_names_uniprotkb": "Gamma-aminobutyric acid receptor subunit beta-2; GABA(A) receptor subunit beta-2",
        "protein_names_refseq": "gamma-aminobutyric acid receptor subunit beta-2 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "gene_name": "LOC101882530",
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        "gene_names_uniprotkb": "LOC101882530",
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    {
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        "protein_name": "Gamma-aminobutyric acid receptor subunit alpha-3 isoform X1",
        "gene_name": "gabra3",
        "organism": "Zebrafish",
        "refseq_name": "gamma-aminobutyric acid receptor subunit alpha-3 isoform X1",
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        "protein_names_refseq": "solute carrier family 22 member 6-A",
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        "organism": "Zebrafish",
        "refseq_name": "rap guanine nucleotide exchange factor 6 isoform X1",
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        "gene_names_refseq": "rapgef6",
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        "protein_names_refseq": "rap guanine nucleotide exchange factor 6 isoform X1",
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        "length": 2176,
        "protein_name": "C-type mannose receptor 2 isoform X1",
        "gene_name": "LOC100537272",
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        "protein_names_refseq": "C-type mannose receptor 2 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "uniprot_id": "A0AC58IBQ5_DANRE",
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        "length": 722,
        "protein_name": "Long-chain-fatty-acid--CoA ligase",
        "gene_name": "acsl6",
        "organism": "Zebrafish",
        "refseq_name": "long-chain-fatty-acid--CoA ligase 6",
        "refseq_ac": "XP_073791662",
        "gene_names_uniprotkb": "acsl6",
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        "protein_names_uniprotkb": "Long-chain-fatty-acid--CoA ligase; 6.2.1.3",
        "protein_names_refseq": "long-chain-fatty-acid--CoA ligase 6",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation., [UniProtKB, UniProtKB]",
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        "ec_number_list": "6.2.1.3;6.2.1.15",
        "go_molecular_function": "GO:0016874 ligase activity",
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    {
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        "length": 138,
        "protein_name": "4a-hydroxytetrahydrobiopterin dehydratase",
        "gene_name": "LOC137488853",
        "organism": "Zebrafish",
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        "protein_names_refseq": "pterin-4-alpha-carbinolamine dehydratase 2-like",
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        "protein_name": "Uncharacterized protein aff1 isoform X1",
        "gene_name": "aff1",
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        "refseq_name": "uncharacterized protein aff1 isoform X1",
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        "gene_names_uniprotkb": "aff1",
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        "protein_names_uniprotkb": "Uncharacterized protein aff1 isoform X1",
        "protein_names_refseq": "uncharacterized protein aff1 isoform X1",
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        "protein_name": "E3 ubiquitin-protein ligase UHRF",
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        "length": 862,
        "protein_name": "Dimethylglycine dehydrogenase, mitochondrial",
        "gene_name": "dmgdh",
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        "protein_names_refseq": "dimethylglycine dehydrogenase, mitochondrial",
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        "length": 173,
        "protein_name": "Melanoma antigen recognized by T-cells 1",
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        "gene_names_refseq": "LOC141379940",
        "protein_names_uniprotkb": "C2H2-type domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]",
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        "synthesized_glycan_count": 0,
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        "record_type": "protein"
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        "length": 163,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC141379941",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073791768",
        "gene_names_uniprotkb": "LOC141379941",
        "gene_names_refseq": "LOC141379941",
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        "protein_names_refseq": "uncharacterized protein isoform X1",
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        "synthesized_glycan_count": 0,
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        "record_id": "A0AC58IC13-1",
        "record_type": "protein"
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        "length": 1077,
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        "gene_name": "LOC141379950",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073791773",
        "gene_names_uniprotkb": "LOC141379950",
        "gene_names_refseq": "LOC141379950",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "synthesized_glycan_count": 0,
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        "record_type": "protein"
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        "uniprot_id": "A0AC58IC31_DANRE",
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        "length": 618,
        "protein_name": "SHC-transforming protein 3 isoform X1",
        "gene_name": "shc3",
        "organism": "Zebrafish",
        "refseq_name": "SHC-transforming protein 3 isoform X1",
        "refseq_ac": "XP_073791790",
        "gene_names_uniprotkb": "shc3",
        "gene_names_refseq": "shc3",
        "protein_names_uniprotkb": "SHC-transforming protein 3 isoform X1",
        "protein_names_refseq": "SHC-transforming protein 3 isoform X1",
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        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0AC58IC46",
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        "go_cellular_component": "",
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        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IC31-1",
        "record_type": "protein"
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        "uniprot_id": "A0AC58IC38_DANRE",
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        "protein_name": "Zinc finger and BTB domain-containing protein 7C isoform X1",
        "gene_name": "zbtb7c",
        "organism": "Zebrafish",
        "refseq_name": "zinc finger and BTB domain-containing protein 7C isoform X1",
        "refseq_ac": "XP_073791794",
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        "gene_names_refseq": "zbtb7c",
        "protein_names_uniprotkb": "Zinc finger and BTB domain-containing protein 7C isoform X1",
        "protein_names_refseq": "zinc finger and BTB domain-containing protein 7C isoform X1",
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        "protein_name": "CBP80/20-dependent translation initiation factor",
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        "organism": "Zebrafish",
        "refseq_name": "CBP80/20-dependent translation initiation factor isoform X1",
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        "protein_names_refseq": "CBP80/20-dependent translation initiation factor isoform X1",
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        "go_molecular_function": "GO:0003743 translation initiation factor activity",
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        "protein_name": "Dymeclin",
        "gene_name": "dym",
        "organism": "Zebrafish",
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        "uniprot_id": "A0AC58IC59_DANRE",
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        "length": 1880,
        "protein_name": "Uncharacterized protein ntng2b isoform X1",
        "gene_name": "ntng2b",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein ntng2b isoform X1",
        "refseq_ac": "XP_073791807",
        "gene_names_uniprotkb": "ntng2b",
        "gene_names_refseq": "ntng2b",
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        "protein_name": "Endothelial cell-specific chemotaxis regulator isoform X1",
        "gene_name": "ecscr",
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        "refseq_name": "endothelial cell-specific chemotaxis regulator isoform X1",
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        "protein_names_refseq": "endothelial cell-specific chemotaxis regulator isoform X1",
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        "length": 494,
        "protein_name": "Uncharacterized protein",
        "gene_name": "LOC141380020",
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        "refseq_name": "uncharacterized protein",
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        "gene_names_uniprotkb": "LOC141380020",
        "gene_names_refseq": "LOC141380020",
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        "protein_names_refseq": "uncharacterized protein",
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        "length": 856,
        "protein_name": "pre-rRNA processing protein FTSJ3",
        "gene_name": "ftsj3",
        "organism": "Zebrafish",
        "refseq_name": "pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 isoform X1",
        "refseq_ac": "XP_073792389",
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        "gene_names_refseq": "cb410; ftsj3; ftsj; sb:cb410; wu:fa08a09",
        "protein_names_uniprotkb": "pre-rRNA processing protein FTSJ3; 2'-O-ribose RNA methyltransferase SPB1 homolog; 2.1.1.-; Protein ftsJ homolog 3; Putative rRNA methyltransferase 3",
        "protein_names_refseq": "pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 isoform X1",
        "tax_id": 7955,
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        "pathway": " (dre:321247)",
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        "ec_number_list": "2.1.1.-",
        "go_molecular_function": "GO:0016435 rRNA (guanine) methyltransferase activity;GO:0008650 rRNA (uridine-2'-O-)-methyltransferase activity;GO:0008168 methyltransferase activity",
        "go_cellular_component": "GO:0005730 nucleolus;GO:0030687 preribosome, large subunit precursor;GO:0030688 preribosome, small subunit precursor",
        "go_biological_process": "GO:0031167 rRNA methylation;GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0032259 methylation",
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        "protein_name": "Platelet-derived growth factor beta polypeptide a isoform X1",
        "gene_name": "pdgfba",
        "organism": "Zebrafish",
        "refseq_name": "platelet-derived growth factor beta polypeptide a isoform X1",
        "refseq_ac": "XP_073792854",
        "gene_names_uniprotkb": "pdgfba; pdgfb; sb:eu1033; si:ch211-79m20.1; si:dkey-261d11.1",
        "gene_names_refseq": "pdgfba; pdgfb; sb:eu1033; si:ch211-79m20.1; si:dkey-261d11.1",
        "protein_names_uniprotkb": "Platelet-derived growth factor beta polypeptide a isoform X1",
        "protein_names_refseq": "platelet-derived growth factor beta polypeptide a isoform X1",
        "tax_id": 7955,
        "disease": "sinusitis (Disease Ontology:DOID:0050127); inflammatory bowel disease (Disease Ontology:DOID:0050589); basal ganglia calcification (Disease Ontology:DOID:0060230); COVID-19 (Disease Ontology:DOID:0080600); graft-versus-host disease (Disease Ontology:DOID:0081267); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); Kuhnt-Junius degeneration (Disease Ontology:DOID:10873); prostatic hypertrophy (Disease Ontology:DOID:11132); oligohydramnios (Disease Ontology:DOID:12215); leiomyoma (Disease Ontology:DOID:127); proliferative diabetic retinopathy (Disease Ontology:DOID:13207); background diabetic retinopathy (Disease Ontology:DOID:13208); cholestasis (Disease Ontology:DOID:13580); Leydig cell tumor (Disease Ontology:DOID:2696); asthma (Disease Ontology:DOID:2841); glomerulonephritis (Disease Ontology:DOID:2921); glioblastoma (Disease Ontology:DOID:3068); high grade glioma (Disease Ontology:DOID:3070); dermatofibrosarcoma protuberans (Disease Ontology:DOID:3507); choriocarcinoma (Disease Ontology:DOID:3594); clear cell renal cell carcinoma (Disease Ontology:DOID:4467); familial meningioma (Disease Ontology:DOID:4586); pancreatitis (Disease Ontology:DOID:4989); liver cirrhosis (Disease Ontology:DOID:5082); ureteral obstruction (Disease Ontology:DOID:5199); pulmonary hypertension (Disease Ontology:DOID:6432); rheumatoid arthritis (Disease Ontology:DOID:7148)",
        "pathway": " (dre:798657)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "16869712;18264099;20593033;23341543;23469178;32738093;33277595;33412105;34310924;37553073",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 28,
        "glyco_site_count": 1,
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        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "GO:0005161 platelet-derived growth factor receptor binding;GO:0008083 growth factor activity",
        "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane",
        "go_biological_process": "GO:1904238 pericyte cell differentiation;GO:0001525 angiogenesis;GO:0008284 positive regulation of cell population proliferation;GO:0030335 positive regulation of cell migration;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0AC58IF46-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IDI5-1",
        "uniprot_id": "A0AC58IDI5_DANRE",
        "mass": 73690.0,
        "length": 638,
        "protein_name": "Centrosomal protein of 70 kDa",
        "gene_name": "cep70",
        "organism": "Zebrafish",
        "refseq_name": "centrosomal protein of 70 kDa isoform X1",
        "refseq_ac": "XP_073792280",
        "gene_names_uniprotkb": "cep70; si:dkey-170g11.4",
        "gene_names_refseq": "cep70; si:dkey-170g11.4",
        "protein_names_uniprotkb": "Centrosomal protein of 70 kDa",
        "protein_names_refseq": "centrosomal protein of 70 kDa isoform X1",
        "tax_id": 7955,
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        "pathway_count": 0,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "missing_score": 10000,
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        "go_molecular_function": "GO:0043015 gamma-tubulin binding",
        "go_cellular_component": "GO:0005576 extracellular region;GO:0005813 centrosome",
        "go_biological_process": "GO:0060271 cilium assembly;GO:0070507 regulation of microtubule cytoskeleton organization;GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IDI5-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IDX9-1",
        "uniprot_id": "A0AC58IDX9_DANRE",
        "mass": 48102.0,
        "length": 427,
        "protein_name": "N-acyl-aliphatic-L-amino acid amidohydrolase",
        "gene_name": "LOC100001620; acy1",
        "organism": "Zebrafish",
        "refseq_name": "aminoacylase-1 isoform X1",
        "refseq_ac": "XP_073792443",
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        "gene_names_refseq": "acy1; si:zfos-226g1.1; zgc:55605; zgc:76955",
        "protein_names_uniprotkb": "N-acyl-aliphatic-L-amino acid amidohydrolase; 3.5.1.14; N-acyl-L-amino-acid amidohydrolase",
        "protein_names_refseq": "aminoacylase-1 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100001620);  (dre:393970)",
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        "publication_count": 2,
        "publication_id_list": "21669877;26104663",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "",
        "ec_number_list": "3.5.1.14;3.5.1.114",
        "go_molecular_function": "GO:0004046 aminoacylase activity;GO:0046872 metal ion binding",
        "go_cellular_component": "GO:0005737 cytoplasm",
        "go_biological_process": "GO:0006520 amino acid metabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "A0AC58IDX9-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IFY8-1",
        "uniprot_id": "A0AC58IFY8_DANRE",
        "mass": 72142.0,
        "length": 651,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC100538212",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073793147",
        "gene_names_uniprotkb": "LOC100538212",
        "gene_names_refseq": "LOC100538212",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100538212)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "record_id": "A0AC58IFY8-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IG96-1",
        "uniprot_id": "A0AC58IG96_DANRE",
        "mass": 32758.0,
        "length": 297,
        "protein_name": "Uncharacterized protein si:ch211-105n15.1 isoform X1",
        "gene_name": "si:ch211-105n15.1",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:ch211-105n15.1 isoform X2",
        "refseq_ac": "XP_009294287",
        "gene_names_uniprotkb": "si:ch211-105n15.1",
        "gene_names_refseq": "si:ch211-105n15.1",
        "protein_names_uniprotkb": "Uncharacterized protein si:ch211-105n15.1 isoform X1",
        "protein_names_refseq": "uncharacterized protein si:ch211-105n15.1 isoform X2",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_009294287.1. COMPLETENESS: full length., [RefSeq]",
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    },
    {
        "uniprot_canonical_ac": "A0AC58IG26-1",
        "uniprot_id": "A0AC58IG26_DANRE",
        "mass": 37707.0,
        "length": 350,
        "protein_name": "Uncharacterized protein si:dkey-222f2.7 isoform X2",
        "gene_name": "si:dkey-222f2.7",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:dkey-222f2.7 isoform X2",
        "refseq_ac": "XP_073793175",
        "gene_names_uniprotkb": "si:dkey-222f2.7",
        "gene_names_refseq": "si:dkey-222f2.7",
        "protein_names_uniprotkb": "Uncharacterized protein si:dkey-222f2.7 isoform X2",
        "protein_names_refseq": "uncharacterized protein si:dkey-222f2.7 isoform X2",
        "tax_id": 7955,
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        "pathway": " (dre:100001516)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "si:ch211-255f4.4; zgc:173486",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073792248",
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        "protein_name": "Si:ch211-255f4.6 isoform X1",
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        "protein_names_refseq": "uncharacterized protein znf1184 isoform X1",
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        "protein_name": "Uncharacterized protein si:ch73-286h23.3 isoform X1",
        "gene_name": "si:ch73-286h23.3",
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        "gene_names_uniprotkb": "si:ch73-286h23.3",
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        "protein_names_uniprotkb": "Uncharacterized protein si:ch73-286h23.3 isoform X1",
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        "go_molecular_function": "GO:0005524 ATP binding",
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        "gene_name": "zgc:171500",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
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        "gene_names_uniprotkb": "zgc:171500; zgc:171500",
        "gene_names_refseq": "zgc:171500",
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        "protein_names_refseq": "uncharacterized protein isoform X1",
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        "record_id": "A0AC58IDE5-1",
        "record_type": "protein"
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        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC137487262",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
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        "gene_names_uniprotkb": "LOC137487262",
        "gene_names_refseq": "LOC137487262",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "record_type": "protein"
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        "uniprot_id": "A0AC58IEN7_DANRE",
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        "length": 809,
        "protein_name": "MICAL-like protein 2a isoform X1",
        "gene_name": "micall2a",
        "organism": "Zebrafish",
        "refseq_name": "MICAL-like protein 2a isoform X1",
        "refseq_ac": "XP_073792708",
        "gene_names_uniprotkb": "micall2a; fd16d06; micall2; wu:fd16d06; wu:fd16d07; zgc:55358",
        "gene_names_refseq": "fd16d06; micall2a; micall2; wu:fd16d06; wu:fd16d07; zgc:55358",
        "protein_names_uniprotkb": "MICAL-like protein 2a isoform X1",
        "protein_names_refseq": "MICAL-like protein 2a isoform X1",
        "tax_id": 7955,
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        "pathway": " (dre:327198)",
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        "publication_id_list": "15520368;16109975;21035094;22438865;31193955;31705559",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "GO:0046872 metal ion binding",
        "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0055037 recycling endosome;GO:0042995 cell projection",
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        "uniprot_id": "A0AC58IDH4_DANRE",
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        "protein_name": "ABI family, member 3 (NESH) binding protein b isoform X1",
        "gene_name": "abi3bpb",
        "organism": "Zebrafish",
        "refseq_name": "ABI family, member 3 (NESH) binding protein b isoform X1",
        "refseq_ac": "XP_073792293",
        "gene_names_uniprotkb": "abi3bpb; abi3bp; wu:fi31h06; zgc:55418",
        "gene_names_refseq": "abi3bpb; abi3bp; wu:fi31h06; zgc:55418",
        "protein_names_uniprotkb": "ABI family, member 3 (NESH) binding protein b isoform X1",
        "protein_names_refseq": "ABI family, member 3 (NESH) binding protein b isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "uniprot_id": "A0AC58IEL7_DANRE",
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        "length": 431,
        "protein_name": "Myocyte-specific enhancer factor 2B isoform X1",
        "gene_name": "mef2b",
        "organism": "Zebrafish",
        "refseq_name": "myocyte-specific enhancer factor 2B isoform X1",
        "refseq_ac": "XP_073792680",
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        "gene_names_refseq": "mef2b; si:ch211-125m10.1",
        "protein_names_uniprotkb": "Myocyte-specific enhancer factor 2B isoform X1",
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        "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding",
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        "hit_score": 0.1,
        "record_id": "A0AC58IEL7-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IDQ0-1",
        "uniprot_id": "A0AC58IDQ0_DANRE",
        "mass": 112342.0,
        "length": 1012,
        "protein_name": "Ephrin type-B receptor 3",
        "gene_name": "ephb3b",
        "organism": "Zebrafish",
        "refseq_name": "ephrin type-B receptor 3b isoform X1",
        "refseq_ac": "XP_073792365",
        "gene_names_uniprotkb": "ephb3b; epha3b; ephb3; sb:eu779",
        "gene_names_refseq": "epha3b; ephb3b; ephb3; sb:eu779",
        "protein_names_uniprotkb": "Ephrin type-B receptor 3; 2.7.10.1",
        "protein_names_refseq": "ephrin type-B receptor 3b isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:108181204)",
        "pathway_count": 1,
        "publication_count": 9,
        "publication_id_list": "16786562;22073277;23234507;26469318;27189481;27825440;31745086;34329618;36830662",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 is involved in the regulation of cell adhesion and cell migration, and plays a central role in heart morphogenesis, angiogenesis and blood vessel remodeling and permeability. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. Involved in somitogenesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": "2.7.10.1;2.7.10.2;2.7.11.1;2.7.12.1;2.7.12.2",
        "go_molecular_function": "GO:0005524 ATP binding;GO:0005003 ephrin receptor activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0030425 dendrite",
        "go_biological_process": "GO:0060429 epithelium development;GO:1990402 embryonic liver development;GO:0007399 nervous system development",
        "synthesized_glycan_count": 0,
        "hit_score": 1.0,
        "record_id": "A0AC58IDQ0-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IDT6-1",
        "uniprot_id": "A0AC58IDT6_DANRE",
        "mass": 31143.0,
        "length": 278,
        "protein_name": "Methyl-CpG-binding domain protein 3b isoform X1",
        "gene_name": "mbd3b",
        "organism": "Zebrafish",
        "refseq_name": "methyl-CpG-binding domain protein 3b isoform X1",
        "refseq_ac": "XP_073792387",
        "gene_names_uniprotkb": "mbd3b; cb357; cb99; mdb3b; sb:cb357; sb:cb99; wu:fc41c05; zgc:111851",
        "gene_names_refseq": "cb357; cb99; mbd3b; mdb3b; sb:cb357; sb:cb99; wu:fc41c05; zgc:111851",
        "protein_names_uniprotkb": "Methyl-CpG-binding domain protein 3b isoform X1",
        "protein_names_refseq": "methyl-CpG-binding domain protein 3b isoform X1",
        "tax_id": 7955,
        "disease": "",
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        "pathway_count": 0,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "GO:0003677 DNA binding",
        "go_cellular_component": "GO:0005654 nucleoplasm",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0060271 cilium assembly;GO:0070121 Kupffer's vesicle development;GO:0002244 hematopoietic progenitor cell differentiation;GO:0060216 definitive hemopoiesis",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IDT6-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IEV2-1",
        "uniprot_id": "A0AC58IEV2_DANRE",
        "mass": 49711.0,
        "length": 438,
        "protein_name": "Src homology 2 domain containing transforming protein D, b isoform X1",
        "gene_name": "shdb",
        "organism": "Zebrafish",
        "refseq_name": "src homology 2 domain containing transforming protein D, b isoform X1",
        "refseq_ac": "XP_073792749",
        "gene_names_uniprotkb": "shdb; shd; si:dkeyp-31e2.2; wu:fb38a12; wu:fi32h10; zgc:153246; zgc:153975; zgc:158798",
        "gene_names_refseq": "shdb; shd; si:dkeyp-31e2.2; wu:fb38a12; wu:fi32h10; zgc:153246; zgc:153975; zgc:158798",
        "protein_names_uniprotkb": "Src homology 2 domain containing transforming protein D, b isoform X1",
        "protein_names_refseq": "src homology 2 domain containing transforming protein D, b isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:564537)",
        "pathway_count": 1,
        "publication_count": 3,
        "publication_id_list": "16109975;19504456;27189481",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "GO:0001784 phosphotyrosine residue binding",
        "go_cellular_component": "",
        "go_biological_process": "GO:0007165 signal transduction;GO:0006915 apoptotic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.4,
        "record_id": "A0AC58IEV2-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58IF41-1",
        "uniprot_id": "A0AC58IF41_DANRE",
        "mass": 24073.0,
        "length": 211,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "si:dkey-169i5.4",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073792849",
        "gene_names_uniprotkb": "si:dkey-169i5.4; fa94f04; wu:fa94f04",
        "gene_names_refseq": "fa94f04; si:dkey-169i5.4; wu:fa94f04",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:796658)",
        "pathway_count": 1,
        "publication_count": 1,
        "publication_id_list": "27189481",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "",
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        "go_molecular_function": "",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0050863 regulation of T cell activation;GO:1903037 regulation of leukocyte cell-cell adhesion",
        "synthesized_glycan_count": 0,
        "hit_score": 0.2,
        "record_id": "A0AC58IF41-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IES5-1",
        "uniprot_id": "A0AC58IES5_DANRE",
        "mass": 88432.0,
        "length": 791,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "si:ch211-129c21.1",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein LOC563087 isoform 1 precursor",
        "refseq_ac": "NP_001428420",
        "gene_names_uniprotkb": "si:ch211-129c21.1; fi18h09; wu:fb73c06; wu:fi18h09",
        "gene_names_refseq": "fi18h09; si:ch211-129c21.1; wu:fb73c06; wu:fi18h09",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "semaphorin 4d; uncharacterized protein LOC563087 isoform 1 precursor",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:563087)",
        "pathway_count": 1,
        "publication_count": 2,
        "publication_id_list": "23499359;26469318",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01035479.1, SRR32588731.1275120.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1. On Jun 12, 2025 this sequence version replaced XP_073792716.1., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
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        "total_reported_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "GO:0030215 semaphorin receptor binding",
        "go_cellular_component": "GO:0016020 membrane",
        "go_biological_process": "GO:0007411 axon guidance",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "A0AC58IES5-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IEY4-1",
        "uniprot_id": "A0AC58IEY4_DANRE",
        "mass": 31278.0,
        "length": 281,
        "protein_name": "Phosphatidylinositol-glycan biosynthesis class X protein",
        "gene_name": "pigx",
        "organism": "Zebrafish",
        "refseq_name": "phosphatidylinositol-glycan biosynthesis class X protein isoform X1",
        "refseq_ac": "XP_073792792",
        "gene_names_uniprotkb": "pigx; si:ch73-159l23.2",
        "gene_names_refseq": "pigx; si:ch73-159l23.2",
        "protein_names_uniprotkb": "Phosphatidylinositol-glycan biosynthesis class X protein",
        "protein_names_refseq": "phosphatidylinositol-glycan biosynthesis class X protein isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:570443);  (R-DRE-162710)",
        "pathway_count": 2,
        "publication_count": 2,
        "publication_id_list": "26469318;27189481",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Stabilizing subunit of the glycosylphosphatidylinositol-mannosyltransferase I complex which catalyzes the transfer of the first mannose, via an alpha-1,4 bond from a dolichol-phosphate-mannose (Dol-P-Man) to the glucosaminyl acyl phosphatidylinositol (GlcN-(acyl)PI) intermediate to generate alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol and participates in the sixth step of the glycosylphosphatidylinositol-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase PIGM., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "predicted_s_glycosites": 0,
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        "total_reported_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane",
        "go_biological_process": "GO:0006506 GPI anchor biosynthetic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "A0AC58IEY4-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IEY8-1",
        "uniprot_id": "A0AC58IEY8_DANRE",
        "mass": 95020.0,
        "length": 854,
        "protein_name": "Elongation factor 2a.2 isoform X1",
        "gene_name": "eef2a.2",
        "organism": "Zebrafish",
        "refseq_name": "elongation factor 2a.2 isoform X1",
        "refseq_ac": "XP_073792776",
        "gene_names_uniprotkb": "eef2a.2; si:dkey-110c1.4",
        "gene_names_refseq": "eef2a.2; si:dkey-110c1.4",
        "protein_names_uniprotkb": "Elongation factor 2a.2 isoform X1",
        "protein_names_refseq": "elongation factor 2a.2 isoform X1",
        "tax_id": 7955,
        "disease": "spinocerebellar ataxia 26 (Disease Ontology:DOID:0050975); prostate cancer (Disease Ontology:DOID:10283); stomach cancer (Disease Ontology:DOID:10534); Alzheimer's disease (Disease Ontology:DOID:10652); glaucoma (Disease Ontology:DOID:1686); rectum adenocarcinoma (Disease Ontology:DOID:1996); colon adenocarcinoma (Disease Ontology:DOID:234); brain glioblastoma multiforme (Disease Ontology:DOID:3073); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); lung small cell carcinoma (Disease Ontology:DOID:5409); colorectal cancer (Disease Ontology:DOID:9256)",
        "pathway": " (dre:568904);  (R-DRE-156902);  (R-DRE-5358493);  (R-DRE-6798695);  (R-DRE-8876725)",
        "pathway_count": 5,
        "publication_count": 2,
        "publication_id_list": "28173755;28252024",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 12,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": "3.6.5.2;3.6.5.3;3.6.5.5;3.6.1.5;3.6.5.-;3.6.1.-;3.6.5.4",
        "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0003746 translation elongation factor activity;GO:0043022 ribosome binding",
        "go_cellular_component": "GO:0005829 cytosol;GO:1990904 ribonucleoprotein complex",
        "go_biological_process": "GO:0006414 translational elongation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "A0AC58IEY8-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IDR3-1",
        "uniprot_id": "A0AC58IDR3_DANRE",
        "mass": 74581.0,
        "length": 668,
        "protein_name": "Anosmin-1b isoform X1",
        "gene_name": "anos1b",
        "organism": "Zebrafish",
        "refseq_name": "anosmin-1b isoform X1",
        "refseq_ac": "XP_073792382",
        "gene_names_uniprotkb": "anos1b; anosmin-1b; kal1.2; kal1b",
        "gene_names_refseq": "anos1b; anosmin-1b; kal1.2; kal1b",
        "protein_names_uniprotkb": "Anosmin-1b isoform X1",
        "protein_names_refseq": "anosmin-1b isoform X1",
        "tax_id": 7955,
        "disease": "hypogonadotropic hypogonadism 1 with or without anosmia (Disease Ontology:DOID:0090094); Kallmann syndrome (Disease Ontology:DOID:3614)",
        "pathway": " (dre:30652);  (R-DRE-190373);  (R-DRE-5654726)",
        "pathway_count": 3,
        "publication_count": 10,
        "publication_id_list": "16109975;16291787;16777316;17064968;18585376;22472058;26278626;26469318;27189481;30122631",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 2,
        "glyco_site_count": 1,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "GO:0030414 peptidase inhibitor activity",
        "go_cellular_component": "GO:0005576 extracellular region;GO:0009986 cell surface",
        "go_biological_process": "GO:0030182 neuron differentiation;GO:0048922 posterior lateral line neuromast deposition",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0AC58IDR3-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IGG2-1",
        "uniprot_id": "A0AC58IGG2_DANRE",
        "mass": 49646.0,
        "length": 442,
        "protein_name": "Uncharacterized protein si:ch73-213k20.5 isoform X1",
        "gene_name": "si:ch73-213k20.5",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:ch73-213k20.5 isoform X1",
        "refseq_ac": "XP_073793319",
        "gene_names_uniprotkb": "si:ch73-213k20.5",
        "gene_names_refseq": "si:ch73-213k20.5",
        "protein_names_uniprotkb": "Uncharacterized protein si:ch73-213k20.5 isoform X1",
        "protein_names_refseq": "uncharacterized protein si:ch73-213k20.5 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100329262)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IGG2-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IFG7-1",
        "uniprot_id": "A0AC58IFG7_DANRE",
        "mass": 56252.0,
        "length": 488,
        "protein_name": "Uncharacterized protein si:ch211-255f4.1 isoform X1",
        "gene_name": "si:ch211-255f4.1",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:ch211-255f4.1 isoform X1",
        "refseq_ac": "XP_073792975",
        "gene_names_uniprotkb": "si:ch211-255f4.1",
        "gene_names_refseq": "si:ch211-255f4.1",
        "protein_names_uniprotkb": "Uncharacterized protein si:ch211-255f4.1 isoform X1",
        "protein_names_refseq": "uncharacterized protein si:ch211-255f4.1 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100534884)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IFG7-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IFY9-1",
        "uniprot_id": "A0AC58IFY9_DANRE",
        "mass": 66414.0,
        "length": 589,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC101884151",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073793157",
        "gene_names_uniprotkb": "LOC101884151",
        "gene_names_refseq": "LOC101884151",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:101884151)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "mined_o_glycosites": 0,
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        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
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        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
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        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IFY9-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IDZ9-1",
        "uniprot_id": "A0AC58IDZ9_DANRE",
        "mass": 91393.0,
        "length": 824,
        "protein_name": "phospholipase A2",
        "gene_name": "pla2g6",
        "organism": "Zebrafish",
        "refseq_name": "85/88 kDa calcium-independent phospholipase A2 isoform X1",
        "refseq_ac": "XP_073792472",
        "gene_names_uniprotkb": "pla2g6; wu:fc06g09; zgc:77476",
        "gene_names_refseq": "pla2g6; wu:fc06g09; zgc:77476",
        "protein_names_uniprotkb": "phospholipase A2; 3.1.1.4",
        "protein_names_refseq": "85/88 kDa calcium-independent phospholipase A2 isoform X1",
        "tax_id": 7955,
        "disease": "Parkinson's disease 14 (Disease Ontology:DOID:0060900); dystonia 12 (Disease Ontology:DOID:0090056); neurodegeneration with brain iron accumulation 2a (Disease Ontology:DOID:0110735); neurodegeneration with brain iron accumulation 2b (Disease Ontology:DOID:0110736); pleurisy (Disease Ontology:DOID:10247); Duchenne muscular dystrophy (Disease Ontology:DOID:11723); neurodegenerative disease (Disease Ontology:DOID:1289); Parkinson's disease (Disease Ontology:DOID:14330); neuroaxonal dystrophy (Disease Ontology:DOID:2367)",
        "pathway": " (dre:406370)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
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        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
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        "total_n_glycosites": 0,
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        "total_c_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 9,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": "3.1.1.32;3.1.1.4;2.3.1.-;3.1.1.3;3.1.1.5",
        "go_molecular_function": "GO:0004623 phospholipase A2 activity",
        "go_cellular_component": "",
        "go_biological_process": "GO:0016042 lipid catabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IDZ9-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IDY2-1",
        "uniprot_id": "A0AC58IDY2_DANRE",
        "mass": 70593.0,
        "length": 647,
        "protein_name": "GTP-binding protein 1",
        "gene_name": "gtpbp1l",
        "organism": "Zebrafish",
        "refseq_name": "GTP binding protein 1, like isoform X1",
        "refseq_ac": "XP_073792452",
        "gene_names_uniprotkb": "gtpbp1l",
        "gene_names_refseq": "gtpbp1l",
        "protein_names_uniprotkb": "GTP-binding protein 1; 3.6.5.3",
        "protein_names_refseq": "GTP binding protein 1, like isoform X1",
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        "pathway": " (dre:402863)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; GTPase that plays a role in the elongation phase of protein synthesis by forming ternary complexes with GTP and aminoacyl-transfer RNAs (aa-tRNAs), and delivering aa-tRNAs to the ribosomal A site in a GTP-dependent manner. Is also able to deliver deacylated tRNA to the A site. Additionally, it is involved in RNA quality control; after GTP hydrolysis, which is not immediately followed by rapid peptide bond formation, GTPBP1 likely retains aa-tRNA in the A site and promotes exosomal degradation of faulty mRNAs engaged in 80S elongation complexes. Plays a role in the regulation of circadian mRNA stability., [UniProtKB, UniProtKB, UniProtKB]",
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        "ec_number_list": "3.6.5.2;3.6.5.3;3.6.5.5;3.6.1.5;3.6.5.-;3.6.1.-;3.6.5.4",
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        "go_cellular_component": "GO:0005737 cytoplasm",
        "go_biological_process": "GO:0001944 vasculature development",
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        "gene_name": "rgs14b",
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        "protein_names_uniprotkb": "Regulator of G-protein signaling 14 isoform X1",
        "protein_names_refseq": "regulator of G-protein signaling 14 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "gene_names_uniprotkb": "gb:ai877918",
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        "protein_names_uniprotkb": "Uncharacterized protein gb:ai877918",
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        "protein_name": "Uncharacterized protein",
        "gene_name": "LOC141380032",
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        "protein_name": "Macrophage mannose receptor 1-like",
        "gene_name": "LOC137487312",
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        "refseq_name": "macrophage mannose receptor 1-like",
        "refseq_ac": "XP_073792203",
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        "gene_names_refseq": "LOC137487312",
        "protein_names_uniprotkb": "Macrophage mannose receptor 1-like",
        "protein_names_refseq": "macrophage mannose receptor 1-like",
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        "predicted_glycosites": 13,
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        "protein_name": "Probable E3 ubiquitin-protein ligase HECTD4",
        "gene_name": "LOC103909470",
        "organism": "Zebrafish",
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        "length": 272,
        "protein_name": "SGNH hydrolase-type esterase domain-containing protein",
        "gene_name": "LOC141380038",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": "XP_073792216",
        "gene_names_uniprotkb": "LOC141380038",
        "gene_names_refseq": "LOC141380038",
        "protein_names_uniprotkb": "SGNH hydrolase-type esterase domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio                   :: 5% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "",
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        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IDB5-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IDC1-1",
        "uniprot_id": "A0AC58IDC1_DANRE",
        "mass": 64933.0,
        "length": 585,
        "protein_name": "Uncharacterized protein",
        "gene_name": "LOC141380041",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": "XP_073792220",
        "gene_names_uniprotkb": "LOC141380041",
        "gene_names_refseq": "LOC141380041",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio                   :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IDC1-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IDC6-1",
        "uniprot_id": "A0AC58IDC6_DANRE",
        "mass": 29685.0,
        "length": 271,
        "protein_name": "Prohibitin",
        "gene_name": "phb",
        "organism": "Zebrafish",
        "refseq_name": "prohibitin 1",
        "refseq_ac": "NP_958454",
        "gene_names_uniprotkb": "phb; fa18f07; fb09f05; sr:nyz128; wu:fa18f07; wu:fb09f05",
        "gene_names_refseq": "fa18f07; fb09f05; phb1; phb; sr:nyz128; wu:fa18f07; wu:fb09f05",
        "protein_names_uniprotkb": "Prohibitin",
        "protein_names_refseq": "prohibitin 1; prohibitin",
        "tax_id": 7955,
        "disease": "urinary bladder cancer (Disease Ontology:DOID:11054); breast cancer (Disease Ontology:DOID:1612); transitional cell carcinoma (Disease Ontology:DOID:2671); sporadic breast cancer (Disease Ontology:DOID:8029); prostate carcinoma in situ (Disease Ontology:DOID:8634); cervix uteri carcinoma in situ (Disease Ontology:DOID:8991)",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 10,
        "publication_id_list": "11116086;16872691;17013923;18212345;24198278;26469318;26876635;27189481;28252024;36238691",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: BC055384.1, EH590645.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC055384.1., [RefSeq]; In the plasma membrane, cooperates with CD86 to mediate CD86-signaling in B lymphocytes that regulates the level of IgG1 produced through the activation of distal signaling intermediates. Upon CD40 engagement, required to activate NF-kappa-B signaling pathway via phospholipase C and protein kinase C activation., [UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
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        "reported_n_glycosites": 0,
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        "reported_c_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
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        "reported_c_glycosites_with_glycan": 0,
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        "reported_fully_resolved_glycans": 0,
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        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 6,
        "glyco_site_count": 0,
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        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005743 mitochondrial inner membrane",
        "go_biological_process": "GO:0071897 DNA biosynthetic process",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0AC58IDC6-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IDC8-1",
        "uniprot_id": "A0AC58IDC8_DANRE",
        "mass": 88227.0,
        "length": 795,
        "protein_name": "Serine/threonine-protein kinase MARK1",
        "gene_name": "mark1",
        "organism": "Zebrafish",
        "refseq_name": "serine/threonine-protein kinase MARK1 isoform X1",
        "refseq_ac": "XP_073792238",
        "gene_names_uniprotkb": "mark1",
        "gene_names_refseq": "mark1",
        "protein_names_uniprotkb": "Serine/threonine-protein kinase MARK1; 2.7.11.1; 2.7.11.26; MAP/microtubule affinity-regulating kinase 1",
        "protein_names_refseq": "serine/threonine-protein kinase MARK1 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Serine/threonine-protein kinase. Involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2 and MAP4. Phosphorylates the microtubule-associated protein MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3)., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "secondary_ac_list": "",
        "ec_number_list": "2.7.11.1;2.7.11.13;2.7.11.25;2.7.10.1;2.7.11.22;2.7.11.21;2.7.11.17;2.7.12.1;2.7.12.2;2.7.11.24;2.7.10.2;2.7.11.26;2.7.11.23;2.7.1.150;2.7.11.12;2.7.11.39;2.7.11.11;2.7.1.153;2.7.1.137;2.7.1.154;2.7.11.31",
        "go_molecular_function": "GO:0016301 kinase activity",
        "go_cellular_component": "",
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        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IDC8-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IDE7-1",
        "uniprot_id": "A0AC58IDE7_DANRE",
        "mass": 20998.0,
        "length": 186,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "si:dkey-222p3.1",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073792259",
        "gene_names_uniprotkb": "si:dkey-222p3.1; si:dkey-21o6.3",
        "gene_names_refseq": "si:dkey-21o6.3; si:dkey-222p3.1",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "record_id": "A0AC58IDE7-1",
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    {
        "uniprot_canonical_ac": "A0AC58IDS4-1",
        "uniprot_id": "A0AC58IDS4_DANRE",
        "mass": 100550.0,
        "length": 888,
        "protein_name": "Scaffold attachment factor B1 isoform X1",
        "gene_name": "safb",
        "organism": "Zebrafish",
        "refseq_name": "scaffold attachment factor B1 isoform X1",
        "refseq_ac": "XP_073792392",
        "gene_names_uniprotkb": "safb; wu:fb40a03; wu:fd42g06; zgc:55387",
        "gene_names_refseq": "safb; wu:fb40a03; wu:fd42g06; zgc:55387",
        "protein_names_uniprotkb": "Scaffold attachment factor B1 isoform X1",
        "protein_names_refseq": "scaffold attachment factor B1 isoform X1",
        "tax_id": 7955,
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        "pathway_count": 0,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "record_id": "A0AC58IDS4-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IDV4-1",
        "uniprot_id": "A0AC58IDV4_DANRE",
        "mass": 67542.0,
        "length": 629,
        "protein_name": "F-box only protein 42 isoform X1",
        "gene_name": "fbxo42",
        "organism": "Zebrafish",
        "refseq_name": "F-box only protein 42",
        "refseq_ac": "NP_001428920",
        "gene_names_uniprotkb": "fbxo42; wu:fj14e08; zgc:64224",
        "gene_names_refseq": "fbxo42; wu:fj14e08; zgc:64224",
        "protein_names_uniprotkb": "F-box only protein 42 isoform X1",
        "protein_names_refseq": "F-box only protein 42",
        "tax_id": 7955,
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        "pathway_count": 0,
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395012.1291101.1, SRR26395062.1039222.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505373 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1. On Jul 17, 2025 this sequence version replaced XP_073792399.1., [RefSeq]",
        "predicted_glycosites": 2,
        "predicted_n_glycosites": 0,
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        "protein_name": "DENN/MADD domain containing 2Db isoform X1",
        "gene_name": "dennd2db",
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        "refseq_name": "DENN/MADD domain containing 2Db isoform X1",
        "refseq_ac": "XP_073792564",
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        "protein_name": "Ribonuclease P protein subunit p14 isoform X1",
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        "protein_name": "C2H2-type domain-containing protein",
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        "gene_name": "LOC101884310",
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        "protein_name": "Chromobox protein homolog 6a isoform X1",
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        "gene_names_uniprotkb": "LOC101884504",
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        "record_type": "protein"
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        "length": 932,
        "protein_name": "LOW QUALITY PROTEIN: uncharacterized protein",
        "gene_name": "LOC101882237",
        "organism": "Zebrafish",
        "refseq_name": "LOW QUALITY PROTEIN: uncharacterized protein",
        "refseq_ac": "XP_073792867",
        "gene_names_uniprotkb": "LOC101882237",
        "gene_names_refseq": "LOC101882237",
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        "protein_names_refseq": "LOW QUALITY PROTEIN: uncharacterized protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio                   :: 1% of CDS bases frameshifts                 :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]",
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        "record_id": "A0AC58IF57-1",
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        "length": 213,
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        "gene_name": "LOC141380084",
        "organism": "Zebrafish",
        "refseq_name": "LOW QUALITY PROTEIN: uncharacterized protein",
        "refseq_ac": "XP_073792868",
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        "gene_names_refseq": "LOC141380084",
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        "protein_names_refseq": "LOW QUALITY PROTEIN: uncharacterized protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio                   :: 17% of CDS bases internal stop codons        :: corrected 3 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "gene_name": "LOC141380093",
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        "protein_names_refseq": "uncharacterized protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio                   :: 3% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Ig-like domain-containing protein",
        "gene_name": "LOC141380089",
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        "protein_name": "GRAM domain-containing protein 2B",
        "gene_name": "si:zfos-943e10.1",
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        "protein_name": "Uncharacterized protein si:ch73-138e16.8",
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        "protein_name": "Ig-like domain-containing protein",
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        "length": 641,
        "protein_name": "Eyes absent homolog",
        "gene_name": "eya4",
        "organism": "Zebrafish",
        "refseq_name": "protein phosphatase EYA4 isoform X2",
        "refseq_ac": "XP_073794468",
        "gene_names_uniprotkb": "eya4; im:7221408; zgc:113079",
        "gene_names_refseq": "eya4; im:7221408; zgc:113079",
        "protein_names_uniprotkb": "Eyes absent homolog; 3.1.3.48",
        "protein_names_refseq": "protein phosphatase EYA4 isoform X2",
        "tax_id": 7955,
        "disease": "dilated cardiomyopathy 1J (Disease Ontology:DOID:0110440); autosomal dominant nonsyndromic deafness 10 (Disease Ontology:DOID:0110542); sensorineural hearing loss (Disease Ontology:DOID:10003); otitis media (Disease Ontology:DOID:10754); dilated cardiomyopathy (Disease Ontology:DOID:12930); branchiootorenal syndrome (Disease Ontology:DOID:14702); eye disease (Disease Ontology:DOID:5614); congestive heart failure (Disease Ontology:DOID:6000)",
        "pathway": " (dre:541552)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "15735644;16109975;18799547;20463905;21925157;28878000;34330825;34779143;36553541;38900908",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "ec_number_list": "3.1.3.16;3.1.3.48;3.1.3.2;3.1.3.67;3.1.3.27;3.1.3.21",
        "go_molecular_function": "GO:0046872 metal ion binding;GO:0004725 protein tyrosine phosphatase activity",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0001964 startle response;GO:0006351 DNA-templated transcription;GO:0007507 heart development;GO:0042472 inner ear morphogenesis;GO:0035050 embryonic heart tube development",
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        "hit_score": 1.1,
        "record_id": "A0AC58IJR1-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IJ45-1",
        "uniprot_id": "A0AC58IJ45_DANRE",
        "mass": 43891.0,
        "length": 401,
        "protein_name": "TAR DNA-binding protein 43",
        "gene_name": "tardbpa",
        "organism": "Zebrafish",
        "refseq_name": "TAR DNA binding protein, like isoform X1",
        "refseq_ac": "XP_073794270",
        "gene_names_uniprotkb": "tardbpa; tardbpl; tardbp; wu:fb52e05; wu:fe47c11; wu:fj94b04",
        "gene_names_refseq": "tardbpa; tardbpl; tardbp; wu:fb52e05; wu:fe47c11; wu:fj94b04",
        "protein_names_uniprotkb": "TAR DNA-binding protein 43",
        "protein_names_refseq": "TAR DNA binding protein, like isoform X1",
        "tax_id": 7955,
        "disease": "obstructive sleep apnea (Disease Ontology:DOID:0050848); amyotrophic lateral sclerosis type 10 (Disease Ontology:DOID:0060201); frontotemporal dementia 2 (Disease Ontology:DOID:0060672); Alzheimer's disease (Disease Ontology:DOID:10652); Pick's disease (Disease Ontology:DOID:11870); Lewy body dementia (Disease Ontology:DOID:12217); neurodegenerative disease (Disease Ontology:DOID:1289); Parkinson's disease (Disease Ontology:DOID:14330); motor neuron disease (Disease Ontology:DOID:231); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); progressive supranuclear palsy (Disease Ontology:DOID:678); frontotemporal dementia (Disease Ontology:DOID:9255)",
        "pathway": " (dre:386630)",
        "pathway_count": 1,
        "publication_count": 11,
        "publication_id_list": "17984093;19959528;23427147;23457265;24117801;31342410;32081878;34903892;37384248;38902734;40044042",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "ec_number_list": "",
        "go_molecular_function": "GO:0003723 RNA binding;GO:0003690 double-stranded DNA binding",
        "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005739 mitochondrion;GO:0000785 chromatin;GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006397 mRNA processing;GO:0007409 axonogenesis;GO:0007528 neuromuscular junction development;GO:0007626 locomotory behavior",
        "synthesized_glycan_count": 0,
        "hit_score": 1.4,
        "record_id": "A0AC58IJ45-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IK22-1",
        "uniprot_id": "A0AC58IK22_DANRE",
        "mass": 140901.0,
        "length": 1277,
        "protein_name": "Calcium-transporting ATPase",
        "gene_name": "atp2b3b",
        "organism": "Zebrafish",
        "refseq_name": "plasma membrane calcium-transporting ATPase 3b isoform X1",
        "refseq_ac": "XP_073794584",
        "gene_names_uniprotkb": "atp2b3b",
        "gene_names_refseq": "atp2b3b",
        "protein_names_uniprotkb": "Calcium-transporting ATPase; 7.2.2.10",
        "protein_names_refseq": "plasma membrane calcium-transporting ATPase 3b isoform X1",
        "tax_id": 7955,
        "disease": "Hailey-Hailey disease (Disease Ontology:DOID:0050429); X-linked spinocerebellar ataxia 1 (Disease Ontology:DOID:0111829); pre-eclampsia (Disease Ontology:DOID:10591); gestational diabetes (Disease Ontology:DOID:11714)",
        "pathway": "",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the hydrolysis of ATP coupled with the transport of calcium., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "ec_number_list": "7.2.2.10",
        "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0005388 P-type calcium transporter activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IK22-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58II20-1",
        "uniprot_id": "A0AC58II20_DANRE",
        "mass": 166088.0,
        "length": 1525,
        "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-79 specific",
        "gene_name": "dot1l",
        "organism": "Zebrafish",
        "refseq_name": "histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1",
        "refseq_ac": "XP_073793894",
        "gene_names_uniprotkb": "dot1l",
        "gene_names_refseq": "dot1l",
        "protein_names_uniprotkb": "Histone-lysine N-methyltransferase, H3 lysine-79 specific; 2.1.1.360; Histone H3-K79 methyltransferase",
        "protein_names_refseq": "histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1",
        "tax_id": 7955,
        "disease": "syndromic intellectual disability (Disease Ontology:DOID:0050888); Nil-Deshwar neurodevelopmental syndrome (Disease Ontology:DOID:0070652); dilated cardiomyopathy 1A (Disease Ontology:DOID:0110425); leukemia (Disease Ontology:DOID:1240); acute biphenotypic leukemia (Disease Ontology:DOID:9953)",
        "pathway": " (dre:559945)",
        "pathway_count": 1,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 3,
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        "missing_score": 10000,
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        "ec_number_list": "2.1.1.360",
        "go_molecular_function": "GO:0140956 histone H3K79 trimethyltransferase activity;GO:0031151 histone H3K79 methyltransferase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0000781 chromosome, telomeric region",
        "go_biological_process": "GO:0060070 canonical Wnt signaling pathway;GO:0032259 methylation;GO:0060729 intestinal epithelial structure maintenance;GO:0051726 regulation of cell cycle;GO:0031509 subtelomeric heterochromatin formation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58II20-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58IIA5-1",
        "uniprot_id": "A0AC58IIA5_DANRE",
        "mass": 87081.0,
        "length": 774,
        "protein_name": "DENN domain-containing protein 1B isoform X1",
        "gene_name": "dennd1b",
        "organism": "Zebrafish",
        "refseq_name": "DENN domain-containing protein 1B isoform X1",
        "refseq_ac": "XP_073793981",
        "gene_names_uniprotkb": "dennd1b",
        "gene_names_refseq": "dennd1b",
        "protein_names_uniprotkb": "DENN domain-containing protein 1B isoform X1",
        "protein_names_refseq": "DENN domain-containing protein 1B isoform X1",
        "tax_id": 7955,
        "disease": "childhood-onset asthma (Disease Ontology:DOID:0080815); asthma (Disease Ontology:DOID:2841); intrinsic asthma (Disease Ontology:DOID:9360); allergic asthma (Disease Ontology:DOID:9415)",
        "pathway": " (dre:560720)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "missing_score": 10000,
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        "glyco_site_count": 0,
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        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity;GO:1901981 phosphatidylinositol phosphate binding",
        "go_cellular_component": "GO:0005829 cytosol;GO:0016607 nuclear speck;GO:0030136 clathrin-coated vesicle",
        "go_biological_process": "GO:0006897 endocytosis;GO:0032456 endocytic recycling",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IIA5-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IIX0-1",
        "uniprot_id": "A0AC58IIX0_DANRE",
        "mass": 205478.0,
        "length": 1897,
        "protein_name": "Collagen alpha-1(XX) chain",
        "gene_name": "slc35h1",
        "organism": "Zebrafish",
        "refseq_name": "",
        "refseq_ac": "",
        "gene_names_uniprotkb": "slc35h1; wu:fb99e07; wu:fc49g11; wu:fi09e02; zgc:55285; zgc:77328",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Collagen alpha-1(XX) chain",
        "protein_names_refseq": "",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:323482)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "Probable collagen protein., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
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        "protein_name": "Si:ch211-226m16.3 protein isoform X1",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588722.10441023.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN18715719, SAMN18715721 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1. On Aug 7, 2025 this sequence version replaced XP_073794449.1., [RefSeq]",
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        "protein_name": "Leucine-rich repeat-containing protein 23",
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        "protein_names_refseq": "leucine-rich repeat-containing protein 23 isoform X1",
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        "disease": "spermatogenic failure 92 (Disease Ontology:DOID:0070591)",
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        "go_cellular_component": "GO:0005576 extracellular region;GO:0005737 cytoplasm;GO:0097729 9+2 motile cilium",
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        "protein_name": "Deoxyhypusine synthase",
        "gene_name": "dhps",
        "organism": "Zebrafish",
        "refseq_name": "deoxyhypusine synthase isoform X1",
        "refseq_ac": "XP_073794329",
        "gene_names_uniprotkb": "dhps; wu:fb52g04; wu:fj48f12; zgc:111900; zgc:56018; zgc:77325",
        "gene_names_refseq": "dhps; wu:fb52g04; wu:fj48f12; zgc:111900; zgc:56018; zgc:77325",
        "protein_names_uniprotkb": "Deoxyhypusine synthase; 2.5.1.46",
        "protein_names_refseq": "deoxyhypusine synthase isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:406329)",
        "pathway_count": 1,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a critical lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. This is the first step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "ec_number_list": "2.5.1.46",
        "go_molecular_function": "GO:0034038 deoxyhypusine synthase activity",
        "go_cellular_component": "",
        "go_biological_process": "GO:0008612 peptidyl-lysine modification to peptidyl-hypusine;GO:0003323 type B pancreatic cell development;GO:0031017 exocrine pancreas development",
        "synthesized_glycan_count": 0,
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        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IJR4-1",
        "uniprot_id": "A0AC58IJR4_DANRE",
        "mass": 55925.0,
        "length": 492,
        "protein_name": "Bridging integrator 2a isoform X1",
        "gene_name": "bin2a",
        "organism": "Zebrafish",
        "refseq_name": "bridging integrator 2a isoform X1",
        "refseq_ac": "XP_073794441",
        "gene_names_uniprotkb": "bin2a; bin2; wu:fb62b04; zgc:101542",
        "gene_names_refseq": "bin2a; bin2; wu:fb62b04; zgc:101542",
        "protein_names_uniprotkb": "Bridging integrator 2a isoform X1",
        "protein_names_refseq": "bridging integrator 2a isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_cellular_component": "GO:0005737 cytoplasm;GO:0012505 endomembrane system",
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        "record_id": "A0AC58IJR4-1",
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    },
    {
        "uniprot_canonical_ac": "A0AC58IJA1-1",
        "uniprot_id": "A0AC58IJA1_DANRE",
        "mass": 14104.0,
        "length": 130,
        "protein_name": "Urotensin 2, alpha isoform X1",
        "gene_name": "uts2a",
        "organism": "Zebrafish",
        "refseq_name": "urotensin 2, alpha isoform X1",
        "refseq_ac": "XP_073794323",
        "gene_names_uniprotkb": "uts2a; UII-a",
        "gene_names_refseq": "UII-a; uts2a",
        "protein_names_uniprotkb": "Urotensin 2, alpha isoform X1",
        "protein_names_refseq": "urotensin 2, alpha isoform X1",
        "tax_id": 7955,
        "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); pre-eclampsia (Disease Ontology:DOID:10591); hypertension (Disease Ontology:DOID:10763); heart disease (Disease Ontology:DOID:114); gestational diabetes (Disease Ontology:DOID:11714); endomyocardial fibrosis (Disease Ontology:DOID:12932); asthma (Disease Ontology:DOID:2841); carotid artery disease (Disease Ontology:DOID:3407); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); pulmonary hypertension (Disease Ontology:DOID:6432); diabetic retinopathy (Disease Ontology:DOID:8947); type 2 diabetes mellitus (Disease Ontology:DOID:9352)",
        "pathway": " (dre:405774)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "16467151;18403048;21447629;22433941;25154920;33721592;34375549;34655691;36736605;39388365",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "ec_number_list": "",
        "go_molecular_function": "GO:0005179 hormone activity",
        "go_cellular_component": "GO:0005576 extracellular region",
        "go_biological_process": "GO:0008217 regulation of blood pressure;GO:0097746 blood vessel diameter maintenance",
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        "record_id": "A0AC58IJA1-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58IGZ9-1",
        "uniprot_id": "A0AC58IGZ9_DANRE",
        "mass": 88329.0,
        "length": 768,
        "protein_name": "Phosphoinositide phospholipase C",
        "gene_name": "plcd4a",
        "organism": "Zebrafish",
        "refseq_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1",
        "refseq_ac": "XP_073793517",
        "gene_names_uniprotkb": "plcd4a",
        "gene_names_refseq": "plcd4a",
        "protein_names_uniprotkb": "Phosphoinositide phospholipase C; 3.1.4.11",
        "protein_names_refseq": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (R-DRE-1855204)",
        "pathway_count": 1,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "",
        "ec_number_list": "3.1.4.11",
        "go_molecular_function": "GO:0004435 phosphatidylinositol-4,5-bisphosphate phospholipase C activity;GO:0005096 GTPase activator activity;GO:0005509 calcium ion binding;GO:0051020 GTPase binding;GO:0030695 GTPase regulator activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane",
        "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0016042 lipid catabolic process;GO:0007223 Wnt signaling pathway, calcium modulating pathway;GO:1901232 regulation of convergent extension involved in axis elongation;GO:1904088 positive regulation of epiboly involved in gastrulation with mouth forming second",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IGZ9-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IIJ3-1",
        "uniprot_id": "A0AC58IIJ3_DANRE",
        "mass": 18186.0,
        "length": 161,
        "protein_name": "Endothelin-3",
        "gene_name": "edn3b",
        "organism": "Zebrafish",
        "refseq_name": "endothelin-3b isoform X1",
        "refseq_ac": "XP_073794020",
        "gene_names_uniprotkb": "edn3b; edn3; si:dkey-211h10.1",
        "gene_names_refseq": "edn3b; edn3; si:dkey-211h10.1",
        "protein_names_uniprotkb": "Endothelin-3; Preproendothelin-3",
        "protein_names_refseq": "endothelin-3b isoform X1",
        "tax_id": 7955,
        "disease": "Waardenburg syndrome type 4B (Disease Ontology:DOID:0110954); Hirschsprung's disease (Disease Ontology:DOID:10487); Waardenburg syndrome (Disease Ontology:DOID:9258)",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Endothelins are endothelium-derived vasoconstrictor peptides., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "go_molecular_function": "",
        "go_cellular_component": "GO:0005576 extracellular region",
        "go_biological_process": "GO:0045634 regulation of melanocyte differentiation;GO:0019229 regulation of vasoconstriction;GO:0042310 vasoconstriction;GO:0030318 melanocyte differentiation;GO:0070285 pigment cell development",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IIJ3-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IJV1-1",
        "uniprot_id": "A0AC58IJV1_DANRE",
        "mass": 44487.0,
        "length": 389,
        "protein_name": "Somatostatin receptor type 5 isoform X1",
        "gene_name": "sstr5",
        "organism": "Zebrafish",
        "refseq_name": "somatostatin receptor type 5 isoform X1",
        "refseq_ac": "XP_073794518",
        "gene_names_uniprotkb": "sstr5; zgc:85682",
        "gene_names_refseq": "sstr5; zgc:85682",
        "protein_names_uniprotkb": "Somatostatin receptor type 5 isoform X1",
        "protein_names_refseq": "somatostatin receptor type 5 isoform X1",
        "tax_id": 7955,
        "disease": "Parkinson's disease (Disease Ontology:DOID:14330); bipolar disorder (Disease Ontology:DOID:3312)",
        "pathway": "",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0004994 somatostatin receptor activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
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    {
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        "uniprot_id": "A0AC58II93_DANRE",
        "mass": 83561.0,
        "length": 775,
        "protein_name": "Transducin-like enhancer protein 4 isoform X1",
        "gene_name": "tle2b",
        "organism": "Zebrafish",
        "refseq_name": "transducin-like enhancer protein 4 isoform X1",
        "refseq_ac": "XP_073793911",
        "gene_names_uniprotkb": "tle2b",
        "gene_names_refseq": "tle2b",
        "protein_names_uniprotkb": "Transducin-like enhancer protein 4 isoform X1",
        "protein_names_refseq": "transducin-like enhancer protein 4 isoform X1",
        "tax_id": 7955,
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        "pathway": " (dre:564019)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "missing_score": 10000,
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        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006355 regulation of DNA-templated transcription",
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        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58III5-1",
        "uniprot_id": "A0AC58III5_DANRE",
        "mass": 24089.0,
        "length": 209,
        "protein_name": "Transcription factor HES-5",
        "gene_name": "her4.2; her4.5",
        "organism": "Zebrafish",
        "refseq_name": "hairy-related 4, tandem duplicate 2 isoform X1",
        "refseq_ac": "XP_073794021",
        "gene_names_uniprotkb": "her4.2; her4.5; Hes5d; fe18g04; si:ch73-21g5.3; si:ch73-21g5.6; wu:fb74d11",
        "gene_names_refseq": "Hes5d; fe18g04; her4.2; si:ch73-21g5.3",
        "protein_names_uniprotkb": "Transcription factor HES-5; Hairy and enhancer of split 5",
        "protein_names_refseq": "hairy-related 4, tandem duplicate 2 isoform X1",
        "tax_id": 7955,
        "disease": "diabetes mellitus (Disease Ontology:DOID:9351)",
        "pathway": " (dre:100148329);  (dre:30301)",
        "pathway_count": 2,
        "publication_count": 19,
        "publication_id_list": "10101116;10357943;11066087;12117818;12160468;15309634;15890328;16544152;17274976;29276941;29363581;29378863;29719254;29720695;32493965;32699896;34234366;34325655;37426341",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Transcriptional repressor of genes that require a bHLH protein for their transcription. Plays an important role as neurogenesis negative regulator., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "secondary_ac_list": "A0AC58III8",
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        "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0048936 peripheral nervous system neuron axonogenesis;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0007219 Notch signaling pathway;GO:0009952 anterior/posterior pattern specification",
        "synthesized_glycan_count": 0,
        "hit_score": 2.0,
        "record_id": "A0AC58III5-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IK54-1",
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        "length": 275,
        "protein_name": "Transmembrane protein 269 isoform X1",
        "gene_name": "tmem269",
        "organism": "Zebrafish",
        "refseq_name": "transmembrane protein 269 isoform X1",
        "refseq_ac": "XP_073794620",
        "gene_names_uniprotkb": "tmem269; si:dkey-205h13.1",
        "gene_names_refseq": "si:dkey-205h13.1; tmem269",
        "protein_names_uniprotkb": "Transmembrane protein 269 isoform X1",
        "protein_names_refseq": "transmembrane protein 269 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:559970)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "go_molecular_function": "GO:0016780 phosphotransferase activity, for other substituted phosphate groups",
        "go_cellular_component": "GO:0016020 membrane",
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        "record_type": "protein"
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        "uniprot_id": "A0AC58IGX3_DANRE",
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        "length": 265,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC108181084",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
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        "gene_names_uniprotkb": "LOC108181084",
        "gene_names_refseq": "LOC108181084",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
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        "predicted_glycosites": 0,
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        "record_id": "A0AC58IGX3-1",
        "record_type": "protein"
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    {
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        "uniprot_id": "A0AC58IGV7_DANRE",
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        "length": 259,
        "protein_name": "Ig-like domain-containing protein",
        "gene_name": "LOC141380179",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": "XP_073793461",
        "gene_names_uniprotkb": "LOC141380179",
        "gene_names_refseq": "LOC141380179",
        "protein_names_uniprotkb": "Ig-like domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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    {
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        "protein_name": "Ig-like domain-containing protein",
        "gene_name": "LOC141380180",
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        "refseq_name": "uncharacterized protein",
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        "gene_names_uniprotkb": "LOC141380180",
        "gene_names_refseq": "LOC141380180",
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        "protein_names_refseq": "uncharacterized protein",
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        "predicted_glycosites": 0,
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        "length": 938,
        "protein_name": "Reverse transcriptase domain-containing protein",
        "gene_name": "LOC141380189",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
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        "gene_names_uniprotkb": "LOC141380189",
        "gene_names_refseq": "LOC141380189",
        "protein_names_uniprotkb": "Reverse transcriptase domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "5-hydroxytryptamine receptor 3C isoform X1",
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        "protein_names_refseq": "5-hydroxytryptamine receptor 3C isoform X1",
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        "protein_names_refseq": "phospholipid-transporting ATPase IF isoform X1",
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        "refseq_name": "5-hydroxytryptamine receptor 3A-like",
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        "gene_names_uniprotkb": "LOC141380243",
        "gene_names_refseq": "LOC141380243",
        "protein_names_uniprotkb": "5-hydroxytryptamine receptor 3A-like",
        "protein_names_refseq": "5-hydroxytryptamine receptor 3A-like",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons., [UniProtKB, UniProtKB]",
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        "length": 450,
        "protein_name": "BBOX and DUF4200 domain-containing protein",
        "gene_name": "si:dkey-37m8.11",
        "organism": "Zebrafish",
        "refseq_name": "BBOX and DUF4200 domain-containing protein",
        "refseq_ac": "NP_001076355",
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        "gene_names_refseq": "si:dkey-37m8.11",
        "protein_names_uniprotkb": "BBOX and DUF4200 domain-containing protein",
        "protein_names_refseq": "BBOX and DUF4200 domain-containing protein",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01041959.1, SRR32588727.3099757.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708836, SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1. On or before Jun 7, 2025 this sequence version replaced XP_073793738.1, NP_001076355.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments., [RefSeq]",
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        "length": 563,
        "protein_name": "Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein",
        "gene_name": "LOC141380259",
        "organism": "Zebrafish",
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        "gene_names_refseq": "LOC141380259",
        "protein_names_uniprotkb": "Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein; Centaurin-beta; Cnt-b",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; GTPase-activating protein for the ADP ribosylation factor family., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "refseq_name": "coiled-coil domain-containing protein 66 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "non-specific serine/threonine protein kinase",
        "gene_name": "LOC141380267",
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        "refseq_name": "uncharacterized protein isoform X1",
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        "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1",
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        "protein_name": "Protein TASOR",
        "gene_name": "tasora",
        "organism": "Zebrafish",
        "refseq_name": "protein TASOR",
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        "gene_names_uniprotkb": "tasora",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "uniprot_canonical_ac": "A0AC58II07-1",
        "uniprot_id": "A0AC58II07_DANRE",
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        "length": 700,
        "protein_name": "Calpain-2 catalytic subunit",
        "gene_name": "capn2l",
        "organism": "Zebrafish",
        "refseq_name": "calpain 2, (m/II) large subunit, like isoform 1",
        "refseq_ac": "NP_001003485",
        "gene_names_uniprotkb": "capn2l",
        "gene_names_refseq": "CH73-80N6.1; capn2l; wu:fb09d04; wu:fb26a06 gene; xx:hac23b03; zgc:112420; zgc:92480",
        "protein_names_uniprotkb": "Calpain-2 catalytic subunit; 3.4.22.53; Calcium-activated neutral proteinase 2; Calpain M-type; Calpain-2 large subunit; Millimolar-calpain",
        "protein_names_refseq": "calpain 2, (m/II) large subunit, like isoform 1",
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        "function": "##Evidence-Data-START## Transcript exon combination :: BC093295.1, GFIL01003013.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476765, SAMEA4476787 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1. On or before Sep 15, 2025 this sequence version replaced XP_073793840.1, NP_001003485.1., [RefSeq]",
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        "protein_name": "E3 ubiquitin-protein ligase",
        "gene_name": "itchb",
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        "gene_names_refseq": "itcha; itchb; itch",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "length": 202,
        "protein_name": "Parvalbumin",
        "gene_name": "pvalb6",
        "organism": "Zebrafish",
        "refseq_name": "parvalbumin 6 isoform X1",
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        "go_molecular_function": "GO:0005509 calcium ion binding",
        "go_cellular_component": "GO:0005737 cytoplasm",
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        "protein_name": "Laminin subunit alpha-5",
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        "refseq_ac": "NP_001428968",
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        "gene_names_refseq": "cb402; im:7138247; lama5; sb:cb402; wu:fb81a10",
        "protein_names_uniprotkb": "Laminin subunit alpha-5; Laminin-10 subunit alpha; Laminin-11 subunit alpha; Laminin-15 subunit alpha",
        "protein_names_refseq": "fransen; fra; laminin subunit alpha-5 isoform 1 precursor; unm m538",
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        "missing_score": 10000,
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        "mass": 88580.0,
        "length": 772,
        "protein_name": "Signal transducer and activator of transcription",
        "gene_name": "stat6",
        "organism": "Zebrafish",
        "refseq_name": "signal transducer and activator of transcription 6 isoform X1",
        "refseq_ac": "XP_073794221",
        "gene_names_uniprotkb": "stat6; sb:eu508; stat7; wu:fj66g07",
        "gene_names_refseq": "sb:eu508; stat6; stat7; wu:fj66g07",
        "protein_names_uniprotkb": "Signal transducer and activator of transcription",
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        "predicted_glycosites": 0,
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        "length": 811,
        "protein_name": "Probable ATP-dependent RNA helicase DDX23",
        "gene_name": "ddx23",
        "organism": "Zebrafish",
        "refseq_name": "probable ATP-dependent RNA helicase DDX23 isoform X1",
        "refseq_ac": "XP_073794217",
        "gene_names_uniprotkb": "ddx23; wu:fi39b12; zgc:63742",
        "gene_names_refseq": "ddx23; wu:fi39b12; zgc:63742",
        "protein_names_uniprotkb": "Probable ATP-dependent RNA helicase DDX23; 3.6.4.13; DEAD box protein 23",
        "protein_names_refseq": "probable ATP-dependent RNA helicase DDX23 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in pre-mRNA splicing and its phosphorylated form (by SRPK2) is required for spliceosomal B complex formation. Independently of its spliceosome formation function, required for the suppression of incorrect R-loops formed during transcription; R-loops are composed of a DNA:RNA hybrid and the associated non-template single-stranded DNA., [UniProtKB, UniProtKB]",
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        "ec_number_list": "2.3.2.-;2.3.2.27;3.6.4.-;4.2.99.18;5.6.2.4;5.6.2.3;3.6.4.12;3.6.4.13;2.7.4.3;7.6.2.2;5.6.1.6;7.6.2.3;3.6.1.5;3.6.4.6;3.6.1.15;3.6.4.10;5.6.2.-;2.7.7.7;2.7.7.49;5.6.2.5;3.6.5.-;3.6.1.-",
        "go_molecular_function": "GO:0004386 helicase activity",
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    },
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        "uniprot_canonical_ac": "A0AC58IJ54-1",
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        "length": 570,
        "protein_name": "Neuronal pentraxin 1 like isoform X1",
        "gene_name": "nptx1l",
        "organism": "Zebrafish",
        "refseq_name": "neuronal pentraxin 1 like isoform X1",
        "refseq_ac": "XP_073794266",
        "gene_names_uniprotkb": "nptx1l; zgc:85889",
        "gene_names_refseq": "nptx1l; zgc:85889",
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        "protein_names_refseq": "neuronal pentraxin 1 like isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "length": 831,
        "protein_name": "Disks large homolog 4 isoform X1",
        "gene_name": "dlg4b",
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        "gene_names_refseq": "dlg4b; dlg4",
        "protein_names_uniprotkb": "Disks large homolog 4 isoform X1",
        "protein_names_refseq": "disks large homolog 4 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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    {
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        "uniprot_id": "A0AC58IJA0_DANRE",
        "mass": 26566.0,
        "length": 236,
        "protein_name": "Rho-related GTP-binding protein Rho6",
        "gene_name": "rnd1a",
        "organism": "Zebrafish",
        "refseq_name": "rho family GTPase 1a isoform X1",
        "refseq_ac": "XP_073794324",
        "gene_names_uniprotkb": "rnd1a; arhs; rho6; rnd1b; rnd1; rno6",
        "gene_names_refseq": "arhs; rho6; rnd1a; rnd1b; rnd1; rno6",
        "protein_names_uniprotkb": "Rho-related GTP-binding protein Rho6; Rho family GTPase 1; Rnd1",
        "protein_names_refseq": "rho family GTPase 1a isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments., [UniProtKB, UniProtKB]",
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    {
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        "uniprot_id": "A0AC58IJD0_DANRE",
        "mass": 67071.0,
        "length": 605,
        "protein_name": "Nuclear receptor subfamily 4immunitygroup A member 1 isoform X1",
        "gene_name": "nr4a1",
        "organism": "Zebrafish",
        "refseq_name": "nuclear receptor subfamily 4immunitygroup A member 1 isoform X1",
        "refseq_ac": "XP_073794352",
        "gene_names_uniprotkb": "nr4a1; NUR77; zgc:92434",
        "gene_names_refseq": "NUR77; nr4a1; zgc:92434",
        "protein_names_uniprotkb": "Nuclear receptor subfamily 4immunitygroup A member 1 isoform X1",
        "protein_names_refseq": "nuclear receptor subfamily 4immunitygroup A member 1 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "secondary_ac_list": "A0AC58IJF1",
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        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58IJJ9-1",
        "uniprot_id": "A0AC58IJJ9_DANRE",
        "mass": 52789.0,
        "length": 481,
        "protein_name": "Solute carrier family 61 member 1",
        "gene_name": "slc61a1",
        "organism": "Zebrafish",
        "refseq_name": "solute carrier family 61 member 1",
        "refseq_ac": "NP_001002713",
        "gene_names_uniprotkb": "slc61a1; mfsd5; zgc:91807",
        "gene_names_refseq": "mfsd5; slc61a1; zgc:91807",
        "protein_names_uniprotkb": "Solute carrier family 61 member 1; Major facilitator superfamily domain-containing protein 5; Molybdate transporter 2 homolog; Molybdate-anion transporter",
        "protein_names_refseq": "major facilitator superfamily domain containing 5; major facilitator superfamily domain-containing protein 5; molybdate transporter 2 homolog; molybdate-anion transporter; solute carrier family 61 member 1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:436986)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: BC076536.1, CF347264.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505372, SAMEA3505376 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC076536.1., [RefSeq]; Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum., [UniProtKB, UniProtKB]",
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        "missing_score": 10000,
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        "secondary_ac_list": "A0A8M9PKP8;A0AC58IJK4;A0AC58IJL1;A0AC58IJL5;A0AC58IJN7",
        "ec_number_list": "",
        "go_molecular_function": "GO:0015098 molybdate ion transmembrane transporter activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0006811 monoatomic ion transport",
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        "record_id": "A0AC58IJJ9-1",
        "record_type": "protein"
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        "protein_name": "Metalloproteinase inhibitor 2",
        "gene_name": "timp2b",
        "organism": "Zebrafish",
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        "protein_names_uniprotkb": "Metalloproteinase inhibitor 2; Tissue inhibitor of metalloproteinases 2",
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        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "GO:0030414 peptidase inhibitor activity",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IJZ2-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IMW5-1",
        "uniprot_id": "A0AC58IMW5_DANRE",
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        "length": 385,
        "protein_name": "Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase isoform X1",
        "gene_name": "st8sia7.2",
        "organism": "Zebrafish",
        "refseq_name": "alpha-N-acetylneuraminide alpha-2,8-sialyltransferase isoform X1",
        "refseq_ac": "XP_073795565",
        "gene_names_uniprotkb": "st8sia7.2",
        "gene_names_refseq": "st8sia7.2",
        "protein_names_uniprotkb": "Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase isoform X1",
        "protein_names_refseq": "alpha-N-acetylneuraminide alpha-2,8-sialyltransferase isoform X1",
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        "pathway": " (dre:567285)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "go_molecular_function": "GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",
        "go_cellular_component": "GO:0000139 Golgi membrane",
        "go_biological_process": "GO:0009311 oligosaccharide metabolic process;GO:0006491 N-glycan processing",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IMW5-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58IL10-1",
        "uniprot_id": "A0AC58IL10_DANRE",
        "mass": 453260.0,
        "length": 3970,
        "protein_name": "Dynein axonemal heavy chain 12",
        "gene_name": "dnah12",
        "organism": "Zebrafish",
        "refseq_name": "dynein axonemal heavy chain 12 isoform X1",
        "refseq_ac": "XP_073794903",
        "gene_names_uniprotkb": "dnah12",
        "gene_names_refseq": "dnah12",
        "protein_names_uniprotkb": "Dynein axonemal heavy chain 12",
        "protein_names_refseq": "dynein axonemal heavy chain 12 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:799461)",
        "pathway_count": 1,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in spermiogenesis. Plays a role in the proper organization of axoneme in sperm flagella, but not in cilia, by recruiting DNAH1 and DNALI1 to flagellum., [UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0005524 ATP binding;GO:0008569 minus-end-directed microtubule motor activity;GO:0051959 dynein light intermediate chain binding;GO:0045505 dynein intermediate chain binding",
        "go_cellular_component": "GO:0005874 microtubule;GO:0036156 inner dynein arm;GO:0097729 9+2 motile cilium",
        "go_biological_process": "GO:0060294 cilium movement involved in cell motility",
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        "hit_score": 0.1,
        "record_id": "A0AC58IL10-1",
        "record_type": "protein"
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        "uniprot_canonical_ac": "A0AC58IL91-1",
        "uniprot_id": "A0AC58IL91_DANRE",
        "mass": 191110.0,
        "length": 1733,
        "protein_name": "Eukaryotic translation initiation factor 4 gamma 3 isoform X1",
        "gene_name": "eif4g3b",
        "organism": "Zebrafish",
        "refseq_name": "eukaryotic translation initiation factor 4 gamma 3 isoform X1",
        "refseq_ac": "XP_073794999",
        "gene_names_uniprotkb": "eif4g3b",
        "gene_names_refseq": "eif4g3b",
        "protein_names_uniprotkb": "Eukaryotic translation initiation factor 4 gamma 3 isoform X1",
        "protein_names_refseq": "eukaryotic translation initiation factor 4 gamma 3 isoform X1",
        "tax_id": 7955,
        "disease": "Parkinson's disease (Disease Ontology:DOID:14330)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "missing_score": 10000,
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        "go_molecular_function": "GO:0003723 RNA binding;GO:0003743 translation initiation factor activity",
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        "go_biological_process": "GO:0006417 regulation of translation",
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        "record_id": "A0AC58IL91-1",
        "record_type": "protein"
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        "uniprot_id": "A0AC58IMW4_DANRE",
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        "length": 1562,
        "protein_name": "Interferon-induced very large GTPase 1 isoform X1",
        "gene_name": "LOC562362",
        "organism": "Zebrafish",
        "refseq_name": "interferon-induced very large GTPase 1 isoform X1",
        "refseq_ac": "XP_073795534",
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        "gene_names_refseq": "LOC562362",
        "protein_names_uniprotkb": "Interferon-induced very large GTPase 1 isoform X1",
        "protein_names_refseq": "interferon-induced very large GTPase 1 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding",
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        "record_type": "protein"
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        "uniprot_id": "A0AC58IL38_DANRE",
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        "length": 1268,
        "protein_name": "Uncharacterized protein ccdc30 isoform X1",
        "gene_name": "ccdc30",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein ccdc30 isoform X1",
        "refseq_ac": "XP_073794921",
        "gene_names_uniprotkb": "ccdc30",
        "gene_names_refseq": "ccdc30",
        "protein_names_uniprotkb": "Uncharacterized protein ccdc30 isoform X1",
        "protein_names_refseq": "uncharacterized protein ccdc30 isoform X1",
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        "secondary_ac_list": "A0AC58IL45",
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        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC101883438",
        "organism": "Zebrafish",
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        "gene_names_uniprotkb": "LOC101883438",
        "gene_names_refseq": "LOC101883438",
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        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
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        "gene_name": "ttll10",
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        "refseq_name": "inactive polyglycylase TTLL10 isoform X1",
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        "protein_names_refseq": "inactive polyglycylase TTLL10 isoform X1",
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        "protein_name": "Protein FAM131C isoform X1",
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        "gene_names_refseq": "fam131c; zgc:110264",
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        "protein_names_refseq": "protein FAM131C isoform X1",
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        "protein_name": "Uncharacterized protein C1orf87 homolog isoform X1",
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        "protein_names_uniprotkb": "Uncharacterized protein C1orf87 homolog isoform X1",
        "protein_names_refseq": "uncharacterized protein C1orf87 homolog isoform X4",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_009295389.1. COMPLETENESS: full length., [RefSeq]",
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        "protein_names_refseq": "sterile alpha motif domain-containing protein 11 isoform X1",
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        "go_biological_process": "GO:0006351 DNA-templated transcription",
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        "protein_names_uniprotkb": "Coiled-coil domain-containing protein 171 isoform X1",
        "protein_names_refseq": "coiled-coil domain-containing protein 171 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "organism": "Zebrafish",
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        "refseq_ac": "XP_073795664",
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        "go_molecular_function": "GO:0005096 GTPase activator activity",
        "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005634 nucleus",
        "go_biological_process": "GO:0007165 signal transduction",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IN57-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IN11-1",
        "uniprot_id": "A0AC58IN11_DANRE",
        "mass": 68021.0,
        "length": 609,
        "protein_name": "ribonuclease H",
        "gene_name": "si:dkey-150i13.2",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:dkey-150i13.2 isoform X1",
        "refseq_ac": "XP_073795632",
        "gene_names_uniprotkb": "si:dkey-150i13.2",
        "gene_names_refseq": "si:dkey-150i13.2",
        "protein_names_uniprotkb": "ribonuclease H; 3.1.26.4",
        "protein_names_refseq": "uncharacterized protein si:dkey-150i13.2 isoform X1",
        "tax_id": 7955,
        "disease": "lipid metabolism disorder (Disease Ontology:DOID:3146)",
        "pathway": " (dre:100003928)",
        "pathway_count": 1,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "reported_c_glycosites_with_glycan": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 1,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "GO:0015227 O-acyl-L-carnitine transmembrane transporter activity",
        "go_cellular_component": "GO:0031966 mitochondrial membrane;GO:0005740 mitochondrial envelope",
        "go_biological_process": "GO:0055085 transmembrane transport;GO:0006839 mitochondrial transport;GO:1902603 carnitine transmembrane transport",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IN11-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58ILM6-1",
        "uniprot_id": "A0AC58ILM6_DANRE",
        "mass": 36403.0,
        "length": 322,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC137489130",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073795128",
        "gene_names_uniprotkb": "LOC137489130",
        "gene_names_refseq": "LOC137489130",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:137489130)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "total_reported_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
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        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58ILM6-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IMV8-1",
        "uniprot_id": "A0AC58IMV8_DANRE",
        "mass": 28461.0,
        "length": 267,
        "protein_name": "6-phosphogluconolactonase",
        "gene_name": "pgls",
        "organism": "Zebrafish",
        "refseq_name": "6-phosphogluconolactonase isoform X1",
        "refseq_ac": "XP_073795577",
        "gene_names_uniprotkb": "pgls; fb11g07; wu:fb11g07; zgc:100853",
        "gene_names_refseq": "fb11g07; pgls; wu:fb11g07; zgc:100853",
        "protein_names_uniprotkb": "6-phosphogluconolactonase; 3.1.1.31; 6PGL",
        "protein_names_refseq": "6-phosphogluconolactonase isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:445494);  (R-DRE-71336)",
        "pathway_count": 2,
        "publication_count": 5,
        "publication_id_list": "16109975;18803863;20102740;26469318;27189481",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "secondary_ac_list": "",
        "ec_number_list": "3.1.1.31",
        "go_molecular_function": "GO:0017057 6-phosphogluconolactonase activity",
        "go_cellular_component": "GO:0005829 cytosol",
        "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0009051 pentose-phosphate shunt, oxidative branch",
        "synthesized_glycan_count": 0,
        "hit_score": 0.6,
        "record_id": "A0AC58IMV8-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IL79-1",
        "uniprot_id": "A0AC58IL79_DANRE",
        "mass": 580605.0,
        "length": 5240,
        "protein_name": "E3 ubiquitin-protein ligase UBR4 isoform X1",
        "gene_name": "ubr4",
        "organism": "Zebrafish",
        "refseq_name": "E3 ubiquitin-protein ligase UBR4 isoform X1",
        "refseq_ac": "XP_073794949",
        "gene_names_uniprotkb": "ubr4",
        "gene_names_refseq": "ubr4",
        "protein_names_uniprotkb": "E3 ubiquitin-protein ligase UBR4 isoform X1",
        "protein_names_refseq": "E3 ubiquitin-protein ligase UBR4 isoform X1",
        "tax_id": 7955,
        "disease": "intellectual disability (Disease Ontology:DOID:1059)",
        "pathway": " (dre:407625)",
        "pathway_count": 1,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "predicted_s_glycosites": 0,
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        "mined_o_glycosites": 0,
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        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
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        "reported_c_glycosites_with_glycan": 0,
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        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
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        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "GO:0005516 calmodulin binding;GO:0008270 zinc ion binding",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IL79-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IMS5-1",
        "uniprot_id": "A0AC58IMS5_DANRE",
        "mass": 57145.0,
        "length": 509,
        "protein_name": "Coronin",
        "gene_name": "coro2ab",
        "organism": "Zebrafish",
        "refseq_name": "coronin-2B isoform X1",
        "refseq_ac": "XP_073795547",
        "gene_names_uniprotkb": "coro2ab",
        "gene_names_refseq": "coro2ab",
        "protein_names_uniprotkb": "Coronin",
        "protein_names_refseq": "coronin-2B isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:555277)",
        "pathway_count": 1,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
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        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
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        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "GO:0051015 actin filament binding",
        "go_cellular_component": "GO:0005884 actin filament;GO:0005886 plasma membrane",
        "go_biological_process": "GO:0007015 actin filament organization",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IMS5-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IKC5-1",
        "uniprot_id": "A0AC58IKC5_DANRE",
        "mass": 100650.0,
        "length": 901,
        "protein_name": "protein-tyrosine-phosphatase",
        "gene_name": "ptpn22",
        "organism": "Zebrafish",
        "refseq_name": "tyrosine-protein phosphatase non-receptor type 22",
        "refseq_ac": "NP_001092890",
        "gene_names_uniprotkb": "ptpn22; ptpn12; si:dkey-78k11.1",
        "gene_names_refseq": "ptpn12; ptpn22; si:dkey-78k11.1",
        "protein_names_uniprotkb": "protein-tyrosine-phosphatase; 3.1.3.48",
        "protein_names_refseq": "protein-tyrosine phosphatase LyPTP; protein-tyrosine phosphatase PEST; tyrosine-protein phosphatase non-receptor type 22",
        "tax_id": 7955,
        "disease": "Graves ophthalmopathy (Disease Ontology:DOID:0081120); graft-versus-host disease (Disease Ontology:DOID:0081267); chronic lymphocytic leukemia (Disease Ontology:DOID:1040); vitiligo (Disease Ontology:DOID:12306); Graves' disease (Disease Ontology:DOID:12361); Sjogren's syndrome (Disease Ontology:DOID:12894); Behcet's disease (Disease Ontology:DOID:13241); temporal arteritis (Disease Ontology:DOID:13375); Addison's disease (Disease Ontology:DOID:13774); hypothyroidism (Disease Ontology:DOID:1459); urticaria (Disease Ontology:DOID:1555); endometriosis (Disease Ontology:DOID:289); pulmonary tuberculosis (Disease Ontology:DOID:2957); coronary artery disease (Disease Ontology:DOID:3393); systemic scleroderma (Disease Ontology:DOID:418); myasthenia gravis (Disease Ontology:DOID:437); systemic juvenile rheumatoid arthritis (Disease Ontology:DOID:676); rheumatoid arthritis (Disease Ontology:DOID:7148); autoimmune thyroiditis (Disease Ontology:DOID:7188); Crohn's disease (Disease Ontology:DOID:8778); psoriasis (Disease Ontology:DOID:8893); autoimmune thrombocytopenic purpura (Disease Ontology:DOID:8924); psoriatic arthritis (Disease Ontology:DOID:9008); systemic lupus erythematosus (Disease Ontology:DOID:9074); diabetes mellitus (Disease Ontology:DOID:9351); type 1 diabetes mellitus (Disease Ontology:DOID:9744); Meniere's disease (Disease Ontology:DOID:9849); alopecia areata (Disease Ontology:DOID:986)",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01031784.1, SRR32588721.1104266.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476749, SAMEA4476750 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1. On or before Aug 4, 2025 this sequence version replaced XP_073794695.1, NP_001092890.1., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 28,
        "glyco_site_count": 0,
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        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "GO:0004726 non-membrane spanning protein tyrosine phosphatase activity",
        "go_cellular_component": "GO:0005737 cytoplasm",
        "go_biological_process": "GO:0007507 heart development",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IKC5-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IK63-1",
        "uniprot_id": "A0AC58IK63_DANRE",
        "mass": 22079.0,
        "length": 195,
        "protein_name": "Transmembrane protein 107",
        "gene_name": "tmem107l",
        "organism": "Zebrafish",
        "refseq_name": "transmembrane protein 107 like isoform X1",
        "refseq_ac": "XP_073794586",
        "gene_names_uniprotkb": "tmem107l; si:dkey-242a8.4",
        "gene_names_refseq": "si:dkey-242a8.4; tmem107l",
        "protein_names_uniprotkb": "Transmembrane protein 107",
        "protein_names_refseq": "transmembrane protein 107 like isoform X1",
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        "disease": "Meckel syndrome 13 (Disease Ontology:DOID:0080253); orofaciodigital syndrome XVI (Disease Ontology:DOID:0080254)",
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        "go_molecular_function": "",
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        "record_type": "protein"
    },
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        "length": 124,
        "protein_name": "Dynein light chain",
        "gene_name": "dnal4a",
        "organism": "Zebrafish",
        "refseq_name": "dynein, axonemal, light chain 4a isoform X1",
        "refseq_ac": "XP_073795500",
        "gene_names_uniprotkb": "dnal4a; zgc:100999",
        "gene_names_refseq": "dnal4a; zgc:100999",
        "protein_names_uniprotkb": "Dynein light chain",
        "protein_names_refseq": "dynein, axonemal, light chain 4a isoform X1",
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        "record_id": "A0AC58IMM9-1",
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    },
    {
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        "length": 303,
        "protein_name": "Uncharacterized protein",
        "gene_name": "LOC141380556",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": "XP_073795515",
        "gene_names_uniprotkb": "LOC141380556",
        "gene_names_refseq": "LOC141380556",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "V-set and transmembrane domain-containing protein 2-like protein",
        "gene_name": "vstm2la",
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        "refseq_name": "V-set and transmembrane domain-containing protein 2-like protein",
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        "protein_name": "LOW QUALITY PROTEIN: uncharacterized protein cntrob",
        "gene_name": "cntrob",
        "organism": "Zebrafish",
        "refseq_name": "LOW QUALITY PROTEIN: uncharacterized protein cntrob",
        "refseq_ac": "XP_073795543",
        "gene_names_uniprotkb": "cntrob",
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        "protein_names_refseq": "LOW QUALITY PROTEIN: uncharacterized protein cntrob",
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        "length": 891,
        "protein_name": "Reelin domain-containing protein 1",
        "gene_name": "reeld1",
        "organism": "Zebrafish",
        "refseq_name": "reeler domain containing 1 precursor",
        "refseq_ac": "NP_001429410",
        "gene_names_uniprotkb": "reeld1",
        "gene_names_refseq": "reeld1",
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        "protein_names_refseq": "reeler domain containing 1 precursor",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588724.1167677.1, SRR32588732.6534552.1 [ECO:0000332] RNAseq introns :: partial sample support SAMN01765705, SAMN18715719 [ECO:0000350] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1. On Aug 8, 2025 this sequence version replaced XP_073795535.1., [RefSeq]",
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        "protein_name": "Interferon-induced very large GTPase 1-like",
        "gene_name": "LOC141380575",
        "organism": "Zebrafish",
        "refseq_name": "interferon-induced very large GTPase 1-like",
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        "protein_names_uniprotkb": "Interferon-induced very large GTPase 1-like",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "length": 955,
        "protein_name": "Cyclin-dependent kinase-like 5",
        "gene_name": "LOC101886244",
        "organism": "Zebrafish",
        "refseq_name": "cyclin-dependent kinase-like 5 isoform X1",
        "refseq_ac": "XP_073795611",
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        "gene_names_refseq": "LOC101886244",
        "protein_names_uniprotkb": "Cyclin-dependent kinase-like 5; 2.7.11.22",
        "protein_names_refseq": "cyclin-dependent kinase-like 5 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Mediates phosphorylation of MECP2. May regulate ciliogenesis., [UniProtKB, UniProtKB, UniProtKB]",
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        "ec_number_list": "2.7.11.1;2.7.11.13;2.7.11.25;2.7.10.1;2.7.11.22;2.7.11.21;2.7.11.17;2.7.12.1;2.7.12.2;2.7.11.24;2.7.10.2;2.7.11.23;2.7.1.150;2.7.11.12;2.7.11.39;2.7.11.11;2.7.1.153;2.7.1.137;2.7.1.154;2.7.11.26;2.7.11.31",
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        "gene_name": "LOC110438316",
        "organism": "Zebrafish",
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        "gene_names_uniprotkb": "LOC110438316",
        "gene_names_refseq": "LOC110438316",
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        "gene_name": "LOC141380595",
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        "refseq_name": "uncharacterized protein isoform X2",
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        "protein_names_refseq": "uncharacterized protein isoform X2",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "ec_number_list": "2.7.7.7;2.7.7.31;2.7.7.49;3.6.4.12;2.7.7.102;4.2.99.18;4.2.99.-",
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        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC101882499",
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        "gene_name": "LOC141380598",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio                   :: 15% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "organism": "Zebrafish",
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        "gene_names_uniprotkb": "LOC137489167",
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        "length": 986,
        "protein_name": "Histone deacetylase",
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        "gene_names_refseq": "hdac7a",
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        "protein_names_refseq": "PTB domain-containing engulfment adapter protein 1-like",
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        "length": 3523,
        "protein_name": "Utrophin isoform X1",
        "gene_name": "utrn",
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        "length": 614,
        "protein_name": "Transmembrane 9 superfamily member",
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        "protein_names_uniprotkb": "Transmembrane 9 superfamily member",
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        "gene_name": "map3k15",
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        "go_cellular_component": "GO:0015630 microtubule cytoskeleton",
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        "protein_name": "Disco-interacting protein 2 homolog C isoform X1",
        "gene_name": "dip2ca",
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        "refseq_name": "disco-interacting protein 2 homolog C isoform X1",
        "refseq_ac": "XP_073796942",
        "gene_names_uniprotkb": "dip2ca",
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        "protein_names_uniprotkb": "Disco-interacting protein 2 homolog C isoform X1",
        "protein_names_refseq": "disco-interacting protein 2 homolog C isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Synaptonemal complex protein 2-like isoform X1",
        "gene_name": "sycp2l",
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        "refseq_name": "synaptonemal complex protein 2-like isoform X1",
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        "gene_names_uniprotkb": "sycp2l",
        "gene_names_refseq": "sycp2l",
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        "protein_names_refseq": "synaptonemal complex protein 2-like isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "length": 458,
        "protein_name": "Succinyl-CoA:glutarate CoA-transferase",
        "gene_name": "sugct",
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        "refseq_name": "succinyl-CoA:glutarate CoA-transferase isoform X1",
        "refseq_ac": "XP_073796617",
        "gene_names_uniprotkb": "sugct; zgc:113390",
        "gene_names_refseq": "sugct; zgc:113390",
        "protein_names_uniprotkb": "Succinyl-CoA:glutarate CoA-transferase; 2.8.3.13; Dicarboxyl-CoA:dicarboxylic acid coenzyme A transferase SUGCT; Succinate--hydroxymethylglutarate CoA-transferase",
        "protein_names_refseq": "succinyl-CoA:glutarate CoA-transferase isoform X1",
        "tax_id": 7955,
        "disease": "glutaric acidemia type 3 (Disease Ontology:DOID:0112246)",
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        "publication_id_list": "12477932",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Coenzyme A (CoA) transferase that reversibly catalyzes the transfer of a CoA moiety from a dicarboxyl-CoA to a dicarboxylate in a metabolite recycling process. Displays preference for succinyl-CoA and glutarate-CoA as dicarboxyl-CoA donors and glutarate, succinate, adipate/hexanedioate, itaconate and 3-hydroxy-3-methylglutarate as dicarboxylate acceptors. Acts on intermediates or end products of lysine and tryptophan degradation pathway, in particular catalyzes succinyl-CoA-dependent reesterification of free glutarate into glutaryl-CoA to prevent renal excretion of glutarate. Upon inflammation, may convert macrophage-derived itaconate to itaconyl-CoA in erythroid precursors where it negatively regulates the TCA cycle and heme synthesis to limit erythroid differentiation in the context of stress erythropoiesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "ec_number_list": "2.8.3.13",
        "go_molecular_function": "GO:0047369 succinate-hydroxymethylglutarate CoA-transferase activity;GO:0016740 transferase activity",
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        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "Gimap9; zgc:122993",
        "organism": "Zebrafish",
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        "gene_names_refseq": "Gimap9; zgc:122993",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "length": 510,
        "protein_name": "Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 2 isoform X1",
        "gene_name": "gnal2",
        "organism": "Zebrafish",
        "refseq_name": "guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 2 isoform 2",
        "refseq_ac": "NP_001427795",
        "gene_names_uniprotkb": "gnal2; Golf2; wu:fa04g06; zgc:92392",
        "gene_names_refseq": "Golf2; gnal2; wu:fa04g06; zgc:92392",
        "protein_names_uniprotkb": "Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 2 isoform X1",
        "protein_names_refseq": "Galpha olf1; guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 2 isoform 2; guanine nucleotide-binding protein G(s) subunit alpha",
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        "pathway": " (dre:407724)",
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        "publication_id_list": "19164534;21242316;26469318;26555542;28026967;28252024",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588718.24727367.1, SRR32588717.54147514.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000024.1. On Jun 3, 2025 this sequence version replaced XP_073796319.1., [RefSeq]",
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        "protein_names_uniprotkb": "Rho GTPase-activating protein 21a isoform X1",
        "protein_names_refseq": "rho GTPase-activating protein 21a isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 5,
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        "gene_name": "adipoqa",
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        "gene_names_refseq": "adipo-a; adipoqa; adipoql2",
        "protein_names_uniprotkb": "Adiponectin isoform X1",
        "protein_names_refseq": "adiponectin isoform X1",
        "tax_id": 7955,
        "disease": "inflammatory bowel disease (Disease Ontology:DOID:0050589); cardiomyopathy (Disease Ontology:DOID:0050700); peripheral artery disease (Disease Ontology:DOID:0050830); sleep apnea (Disease Ontology:DOID:0050847); tongue squamous cell carcinoma (Disease Ontology:DOID:0050865); stroke (Disease Ontology:DOID:0051061); colitis (Disease Ontology:DOID:0060180); metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); graft-versus-host disease (Disease Ontology:DOID:0081267); Alzheimer's disease (Disease Ontology:DOID:10652); primary open angle glaucoma (Disease Ontology:DOID:1070); polycystic ovary syndrome (Disease Ontology:DOID:11612); familial hyperlipidemia (Disease Ontology:DOID:1168); gestational diabetes (Disease Ontology:DOID:11714); Rett syndrome (Disease Ontology:DOID:1206); Graves' disease (Disease Ontology:DOID:12361); cardiovascular system disease (Disease Ontology:DOID:1287); dementia (Disease Ontology:DOID:1307); proliferative diabetic retinopathy (Disease Ontology:DOID:13207); Behcet's disease (Disease Ontology:DOID:13241); Kawasaki disease (Disease Ontology:DOID:13378); biliary atresia (Disease Ontology:DOID:13608); diffuse scleroderma (Disease Ontology:DOID:1580); breast cancer (Disease Ontology:DOID:1612); vascular disease (Disease Ontology:DOID:178); atherosclerosis (Disease Ontology:DOID:1936); hyperinsulinism (Disease Ontology:DOID:2018); autoimmune hepatitis (Disease Ontology:DOID:2048); multiple sclerosis (Disease Ontology:DOID:2377); prostate adenocarcinoma (Disease Ontology:DOID:2526); Mycobacterium avium complex disease (Disease Ontology:DOID:2755); pulmonary tuberculosis (Disease Ontology:DOID:2957); familial Mediterranean fever (Disease Ontology:DOID:2987); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); bipolar disorder (Disease Ontology:DOID:3312); coronary aneurysm (Disease Ontology:DOID:3362); coronary artery disease (Disease Ontology:DOID:3393); brain infarction (Disease Ontology:DOID:3454); liver cirrhosis (Disease Ontology:DOID:5082); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); hepatocellular carcinoma (Disease Ontology:DOID:684); ankylosing spondylitis (Disease Ontology:DOID:7147); rheumatoid arthritis (Disease Ontology:DOID:7148); end stage renal disease (Disease Ontology:DOID:783); hyperthyroidism (Disease Ontology:DOID:7998); ulcerative colitis (Disease Ontology:DOID:8577); Crohn's disease (Disease Ontology:DOID:8778); diabetic retinopathy (Disease Ontology:DOID:8947); amyloidosis (Disease Ontology:DOID:9120); type 2 diabetes mellitus (Disease Ontology:DOID:9352); steatotic liver disease (Disease Ontology:DOID:9452); type 1 diabetes mellitus (Disease Ontology:DOID:9744); obesity (Disease Ontology:DOID:9970)",
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        "mass": 33970.0,
        "length": 300,
        "protein_name": "Protein FAM13A isoform X1",
        "gene_name": "LOC137489173",
        "organism": "Zebrafish",
        "refseq_name": "protein FAM13A isoform X1",
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        "gene_names_uniprotkb": "LOC137489173",
        "gene_names_refseq": "LOC137489173",
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        "tax_id": 7955,
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        "gene_name": "LOC137489218",
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        "refseq_name": "B-cell receptor CD22-like isoform X1",
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        "protein_names_refseq": "B-cell receptor CD22-like isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "protein_name": "Periplakin isoform X1",
        "gene_name": "ppl",
        "organism": "Zebrafish",
        "refseq_name": "periplakin isoform X1",
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        "gene_names_uniprotkb": "ppl; cb180; im:7140067; im:7149519; sb:cb180",
        "gene_names_refseq": "cb180; im:7140067; im:7149519; ppl; sb:cb180",
        "protein_names_uniprotkb": "Periplakin isoform X1",
        "protein_names_refseq": "periplakin isoform X1",
        "tax_id": 7955,
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        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0016020 membrane;GO:0001533 cornified envelope;GO:0030057 desmosome",
        "go_biological_process": "GO:0031424 keratinization;GO:0042060 wound healing;GO:0045104 intermediate filament cytoskeleton organization",
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        "refseq_ac": "XP_073796788",
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        "gene_names_refseq": "sp100.4; zgc:113411; zgc:173656",
        "protein_names_uniprotkb": "SP110 nuclear antigen, tandem duplicate 4 isoform X1",
        "protein_names_refseq": "SP110 nuclear antigen, tandem duplicate 4 isoform X1",
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        "disease": "hepatic venoocclusive disease with immunodeficiency (Disease Ontology:DOID:0112254); tuberculosis (Disease Ontology:DOID:399)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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    {
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        "length": 1101,
        "protein_name": "Importin-4 isoform X1",
        "gene_name": "ipo4",
        "organism": "Zebrafish",
        "refseq_name": "importin-4 isoform X1",
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        "gene_names_uniprotkb": "ipo4",
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        "protein_names_uniprotkb": "Importin-4 isoform X1",
        "protein_names_refseq": "importin-4 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "GO:0031267 small GTPase binding;GO:0008139 nuclear localization sequence binding;GO:0061608 nuclear import signal receptor activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm",
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        "length": 119,
        "protein_name": "C-C motif chemokine 34b.8 isoform X1",
        "gene_name": "ccl34b.8",
        "organism": "Zebrafish",
        "refseq_name": "C-C motif chemokine 34b.8 precursor",
        "refseq_ac": "NP_001373498",
        "gene_names_uniprotkb": "ccl34b.8; si:dkey-25o1.4",
        "gene_names_refseq": "ccl34b.8; si:dkey-25o1.4",
        "protein_names_uniprotkb": "C-C motif chemokine 34b.8 isoform X1",
        "protein_names_refseq": "C-C motif chemokine 34b.8 precursor; CCL-chr24c; CCL34bh; chemokine CCL-C24c",
        "tax_id": 7955,
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        "pathway": " (dre:100331911)",
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        "publication_id_list": "18482437;23145839;29760055;31072958;35111746",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588725.53894778.1, SRR32588722.22414265.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476783, SAMEA4476810 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000024.1. On or before Jul 21, 2025 this sequence version replaced XP_073796064.1, NP_001373498.2., [RefSeq]",
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        "go_molecular_function": "GO:0008009 chemokine activity",
        "go_cellular_component": "GO:0005615 extracellular space",
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        "uniprot_canonical_ac": "A0AC58INI6-1",
        "uniprot_id": "A0AC58INI6_DANRE",
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        "length": 1688,
        "protein_name": "Coiled-coil and C2 domain-containing protein 2A isoform X1",
        "gene_name": "cc2d2a",
        "organism": "Zebrafish",
        "refseq_name": "coiled-coil and C2 domain-containing protein 2A isoform X1",
        "refseq_ac": "XP_073795759",
        "gene_names_uniprotkb": "cc2d2a",
        "gene_names_refseq": "cc2d2a",
        "protein_names_uniprotkb": "Coiled-coil and C2 domain-containing protein 2A isoform X1",
        "protein_names_refseq": "coiled-coil and C2 domain-containing protein 2A isoform X1",
        "tax_id": 7955,
        "disease": "visceral heterotaxy (Disease Ontology:DOID:0050545); Joubert syndrome (Disease Ontology:DOID:0050777); Meckel syndrome (Disease Ontology:DOID:0050778); ciliopathy (Disease Ontology:DOID:0060340); retinitis pigmentosa 93 (Disease Ontology:DOID:0061105); Meckel syndrome 6 (Disease Ontology:DOID:0070120); Joubert syndrome 9 (Disease Ontology:DOID:0111004); intellectual disability (Disease Ontology:DOID:1059)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "go_cellular_component": "GO:0032391 photoreceptor connecting cilium;GO:0035869 ciliary transition zone",
        "go_biological_process": "GO:0035845 photoreceptor cell outer segment organization;GO:1905515 non-motile cilium assembly;GO:1904491 protein localization to ciliary transition zone",
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        "length": 1025,
        "protein_name": "Multidrug resistance-associated protein 1 isoform X1",
        "gene_name": "abcc13",
        "organism": "Zebrafish",
        "refseq_name": "multidrug resistance-associated protein 1 isoform X1",
        "refseq_ac": "XP_073796816",
        "gene_names_uniprotkb": "abcc13",
        "gene_names_refseq": "abcc13",
        "protein_names_uniprotkb": "Multidrug resistance-associated protein 1 isoform X1",
        "protein_names_refseq": "multidrug resistance-associated protein 1 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140359 ABC-type transporter activity",
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        "protein_name": "Anion exchange protein",
        "gene_name": "slc4a2b",
        "organism": "Zebrafish",
        "refseq_name": "anion exchange protein 2b isoform X1",
        "refseq_ac": "XP_073796609",
        "gene_names_uniprotkb": "slc4a2b; ae2.1; sb:cb330; slc4a2.1",
        "gene_names_refseq": "ae2.1; sb:cb330; slc4a2.1; slc4a2b",
        "protein_names_uniprotkb": "Anion exchange protein",
        "protein_names_refseq": "anion exchange protein 2b isoform X1",
        "tax_id": 7955,
        "disease": "autosomal recessive polycystic kidney disease (Disease Ontology:DOID:0110861); prediabetes syndrome (Disease Ontology:DOID:11716); osteopetrosis (Disease Ontology:DOID:13533); anemia (Disease Ontology:DOID:2355)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "protein_names_refseq": "thyrotropin subunit beta",
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        "length": 668,
        "protein_name": "Glutathione hydrolase",
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        "protein_names_uniprotkb": "Glutathione hydrolase; 2.3.2.2; 3.4.19.13; Gamma-glutamyltransferase; Gamma-glutamyltranspeptidase",
        "protein_names_refseq": "glutathione hydrolase 7 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "protein_name": "Probable ATP-dependent RNA helicase DHX35",
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        "organism": "Zebrafish",
        "refseq_name": "probable ATP-dependent RNA helicase DHX35",
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        "protein_names_refseq": "probable ATP-dependent RNA helicase DHX35",
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        "protein_name": "Inactive serine protease 35",
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        "organism": "Zebrafish",
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        "go_biological_process": "GO:0006508 proteolysis",
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        "gene_name": "LOC137489072",
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        "gene_name": "LOC137489080",
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        "predicted_glycosites": 0,
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        "synthesized_glycan_count": 0,
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        "record_id": "A0AC58INK3-1",
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        "length": 499,
        "protein_name": "NIDO domain-containing protein",
        "gene_name": "LOC141380623",
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        "refseq_name": "uncharacterized protein",
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        "gene_names_refseq": "LOC141380623",
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        "protein_names_refseq": "uncharacterized protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "record_id": "A0AC58INK7-1",
        "record_type": "protein"
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        "uniprot_id": "A0AC58INL7_DANRE",
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        "length": 528,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC103908677",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073795839",
        "gene_names_uniprotkb": "LOC103908677",
        "gene_names_refseq": "LOC103908677",
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        "protein_names_refseq": "uncharacterized protein isoform X1",
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    {
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        "uniprot_id": "A0AC58INP0_DANRE",
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        "length": 495,
        "protein_name": "Patatin-like phospholipase domain-containing protein 2",
        "gene_name": "pnpla1",
        "organism": "Zebrafish",
        "refseq_name": "patatin-like phospholipase domain-containing protein 2",
        "refseq_ac": "XP_073795857",
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        "gene_names_refseq": "pnpla1",
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        "protein_names_refseq": "patatin-like phospholipase domain-containing protein 2",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "length": 170,
        "protein_name": "Troponin I, slow skeletal muscle",
        "gene_name": "tnni1a",
        "organism": "Zebrafish",
        "refseq_name": "troponin I, slow skeletal muscle",
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        "gene_names_uniprotkb": "tnni1a",
        "gene_names_refseq": "tnni1a",
        "protein_names_uniprotkb": "Troponin I, slow skeletal muscle",
        "protein_names_refseq": "troponin I, slow skeletal muscle",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity., [UniProtKB, UniProtKB]",
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    {
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        "mass": 84711.0,
        "length": 749,
        "protein_name": "Reverse transcriptase domain-containing protein",
        "gene_name": "LOC141380632",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
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        "gene_names_uniprotkb": "LOC141380632",
        "gene_names_refseq": "LOC141380632",
        "protein_names_uniprotkb": "Reverse transcriptase domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
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        "length": 440,
        "protein_name": "Glutaryl-CoA dehydrogenase, mitochondrial",
        "gene_name": "gcdhb",
        "organism": "Zebrafish",
        "refseq_name": "glutaryl-CoA dehydrogenase b isoform 1",
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        "protein_names_refseq": "glutaryl-CoA dehydrogenase b isoform 1; glutaryl-Coenzyme A dehydrogenase, like",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588715.1700279.1, SRR32588722.45815732.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505373, SAMEA3505376 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1. On Sep 3, 2025 this sequence version replaced XP_073796080.1., [RefSeq]",
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        "protein_name": "receptor protein-tyrosine kinase",
        "gene_name": "ek1",
        "organism": "Zebrafish",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "ec_number_list": "2.7.10.1;2.7.10.2;2.7.11.1;2.7.12.1;2.7.12.2",
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    },
    {
        "uniprot_canonical_ac": "A0AC58IPJ6-1",
        "uniprot_id": "A0AC58IPJ6_DANRE",
        "mass": 79553.0,
        "length": 739,
        "protein_name": "Granulin b isoform X1",
        "gene_name": "grnb",
        "organism": "Zebrafish",
        "refseq_name": "granulin b isoform X1",
        "refseq_ac": "XP_073796162",
        "gene_names_uniprotkb": "grnb; fj14b08; wu:fj14b08; zgc:111858",
        "gene_names_refseq": "fj14b08; grnb; wu:fj14b08; zgc:111858",
        "protein_names_uniprotkb": "Granulin b isoform X1",
        "protein_names_refseq": "granulin b isoform X1",
        "tax_id": 7955,
        "disease": "primary progressive multiple sclerosis (Disease Ontology:DOID:0050784); frontotemporal dementia 2 (Disease Ontology:DOID:0060672); neuronal ceroid lipofuscinosis 11 (Disease Ontology:DOID:0110732); Alzheimer's disease (Disease Ontology:DOID:10652); nephrogenic diabetes insipidus (Disease Ontology:DOID:12387); autistic disorder (Disease Ontology:DOID:12849); dementia (Disease Ontology:DOID:1307); Parkinson's disease (Disease Ontology:DOID:14330); status epilepticus (Disease Ontology:DOID:1824); atherosclerosis (Disease Ontology:DOID:1936); multiple sclerosis (Disease Ontology:DOID:2377); relapsing-remitting multiple sclerosis (Disease Ontology:DOID:2378); bipolar disorder (Disease Ontology:DOID:3312); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); frontotemporal dementia (Disease Ontology:DOID:9255)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "secondary_ac_list": "A0AC58IPK7",
        "ec_number_list": "",
        "go_molecular_function": "",
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        "go_biological_process": "",
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        "hit_score": 0.1,
        "record_id": "A0AC58IPJ6-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IPQ8-1",
        "uniprot_id": "A0AC58IPQ8_DANRE",
        "mass": 33076.0,
        "length": 295,
        "protein_name": "Translocon-associated protein subunit alpha",
        "gene_name": "ssr1",
        "organism": "Zebrafish",
        "refseq_name": "translocon-associated protein subunit alpha isoform X1",
        "refseq_ac": "XP_073796220",
        "gene_names_uniprotkb": "ssr1; cb758",
        "gene_names_refseq": "cb758; ssr1",
        "protein_names_uniprotkb": "Translocon-associated protein subunit alpha; Signal sequence receptor subunit alpha; TRAP-alpha",
        "protein_names_refseq": "translocon-associated protein subunit alpha isoform X1",
        "tax_id": 7955,
        "disease": "",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins., [UniProtKB, UniProtKB, UniProtKB]",
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    },
    {
        "uniprot_canonical_ac": "A0AC58IQ12-1",
        "uniprot_id": "A0AC58IQ12_DANRE",
        "mass": 19020.0,
        "length": 175,
        "protein_name": "Hemoglobin, alpha adult 2 isoform X1",
        "gene_name": "hbaa2",
        "organism": "Zebrafish",
        "refseq_name": "hemoglobin, alpha adult 2 isoform X1",
        "refseq_ac": "XP_073796316",
        "gene_names_uniprotkb": "hbaa2; si:ch211-5k11.6; si:xx-187g17.5; si:xx-by187g17.5; zgc:112086",
        "gene_names_refseq": "hbaa2; si:ch211-5k11.6; si:xx-187g17.5; si:xx-by187g17.5; zgc:112086",
        "protein_names_uniprotkb": "Hemoglobin, alpha adult 2 isoform X1",
        "protein_names_refseq": "hemoglobin, alpha adult 2 isoform X1",
        "tax_id": 7955,
        "disease": "hemoglobin H disease (Disease Ontology:DOID:0110031); Heinz body anemia (Disease Ontology:DOID:0111363); familial erythrocytosis 7 (Disease Ontology:DOID:0111631); Alzheimer's disease (Disease Ontology:DOID:10652); alpha thalassemia (Disease Ontology:DOID:1099)",
        "pathway": " (dre:497166)",
        "pathway_count": 1,
        "publication_count": 8,
        "publication_id_list": "22537494;23413775;27189481;27340786;28252024;28333290;33321129;38040044",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0019825 oxygen binding;GO:0005344 oxygen carrier activity",
        "go_cellular_component": "GO:0005833 hemoglobin complex;GO:0031838 haptoglobin-hemoglobin complex",
        "go_biological_process": "GO:0048821 erythrocyte development;GO:0015671 oxygen transport",
        "synthesized_glycan_count": 0,
        "hit_score": 0.9,
        "record_id": "A0AC58IQ12-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58IQ20-1",
        "uniprot_id": "A0AC58IQ20_DANRE",
        "mass": 99576.0,
        "length": 842,
        "protein_name": "DNA topoisomerase I",
        "gene_name": "top1mt",
        "organism": "Zebrafish",
        "refseq_name": "DNA topoisomerase I, mitochondrial isoform 2",
        "refseq_ac": "NP_001429250",
        "gene_names_uniprotkb": "top1mt",
        "gene_names_refseq": "top1mt",
        "protein_names_uniprotkb": "DNA topoisomerase I; 5.6.2.1; DNA topoisomerase 1",
        "protein_names_refseq": "DNA topoisomerase I, mitochondrial isoform 2; mitochondrial topoisomerase I; topoisomerase (DNA) I, mitochondrial",
        "tax_id": 7955,
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        "pathway": "",
        "pathway_count": 0,
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        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01041681.1, SRR32588717.38263517.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN18715719 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000024.1. On Jul 31, 2025 this sequence version replaced XP_073796323.1., [RefSeq]; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "record_id": "A0AC58IQ20-1",
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    {
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        "length": 446,
        "protein_name": "C-C chemokine receptor type 10 isoform X1",
        "gene_name": "ccr10",
        "organism": "Zebrafish",
        "refseq_name": "C-C chemokine receptor type 10 isoform X1",
        "refseq_ac": "XP_073796362",
        "gene_names_uniprotkb": "ccr10; zgc:91924",
        "gene_names_refseq": "ccr10; zgc:91924",
        "protein_names_uniprotkb": "C-C chemokine receptor type 10 isoform X1",
        "protein_names_refseq": "C-C chemokine receptor type 10 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "record_id": "A0AC58IQ60-1",
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    {
        "uniprot_canonical_ac": "A0AC58IQI6-1",
        "uniprot_id": "A0AC58IQI6_DANRE",
        "mass": 54341.0,
        "length": 486,
        "protein_name": "protein disulfide-isomerase",
        "gene_name": "tmx3b",
        "organism": "Zebrafish",
        "refseq_name": "protein disulfide-isomerase TMX3 isoform X2",
        "refseq_ac": "XP_073796484",
        "gene_names_uniprotkb": "tmx3b; zgc:152808",
        "gene_names_refseq": "tmx3b; zgc:152808",
        "protein_names_uniprotkb": "protein disulfide-isomerase; 5.3.4.1",
        "protein_names_refseq": "protein disulfide-isomerase TMX3 isoform X2",
        "tax_id": 7955,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Probable disulfide isomerase, which participates in the folding of proteins containing disulfide bonds. May act as a dithiol oxidase. Acts as a regulator of endoplasmic reticulum-mitochondria contact sites via its ability to regulate redox signals., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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    {
        "uniprot_canonical_ac": "A0AC58IQZ8-1",
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        "mass": 31004.0,
        "length": 278,
        "protein_name": "small monomeric GTPase",
        "gene_name": "zgc:112183",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X3",
        "refseq_ac": "XP_073796670",
        "gene_names_uniprotkb": "zgc:112183; zgc:112183",
        "gene_names_refseq": "zgc:112183",
        "protein_names_uniprotkb": "small monomeric GTPase; 3.6.5.2",
        "protein_names_refseq": "uncharacterized protein isoform X3",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "ec_number_list": "3.6.5.2;3.6.5.3;3.6.5.5;3.6.1.5;3.6.5.-;3.6.1.-;3.6.5.4",
        "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0003925 G protein activity",
        "go_cellular_component": "GO:0005768 endosome;GO:0005886 plasma membrane;GO:0008021 synaptic vesicle;GO:0030140 trans-Golgi network transport vesicle",
        "go_biological_process": "GO:0015031 protein transport;GO:0006887 exocytosis;GO:0032456 endocytic recycling",
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    {
        "uniprot_canonical_ac": "A0AC58IQY5-1",
        "uniprot_id": "A0AC58IQY5_DANRE",
        "mass": 34449.0,
        "length": 295,
        "protein_name": "Elongation of very long chain fatty acids protein 2",
        "gene_name": "elovl2",
        "organism": "Zebrafish",
        "refseq_name": "very long chain fatty acid elongase 2",
        "refseq_ac": "NP_001035452",
        "gene_names_uniprotkb": "elovl2; ELOVL2; zgc:136352",
        "gene_names_refseq": "elovl2; zgc:136352",
        "protein_names_uniprotkb": "Elongation of very long chain fatty acids protein 2; 2.3.1.199; 3-keto acyl-CoA synthase ELOVL2; ELOVL FA elongase 2; ELOVL fatty acid elongase 2; Very long chain 3-ketoacyl-CoA synthase 2; Very long chain 3-oxoacyl-CoA synthase 2",
        "protein_names_refseq": "elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2; very long chain fatty acid elongase 2",
        "tax_id": 7955,
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        "function": "##Evidence-Data-START## Transcript exon combination :: BC115092.1, EH505744.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000024.1. On or before Sep 16, 2025 this sequence version replaced XP_073796653.1, NP_001035452.1. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators., [UniProtKB, HAMAP]; This study investigated the expression of genes encoding enzymes involved in long-chain polyunsaturated fatty acids biosynthesis, namely fatty acyl desaturase (Fad) and Elovl5- and Elovl2-like elongases, during early embryonic development of zebrafish., [RefSeq, PubMed]",
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        "protein_name": "Dystrobrevin",
        "gene_name": "dtna",
        "organism": "Zebrafish",
        "refseq_name": "dystrobrevin alpha isoform X1",
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        "gene_names_refseq": "adtn; atnb; dtna",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Polycystin-1-like protein 1 isoform X1",
        "gene_name": "pkd1l1",
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        "refseq_name": "polycystin-1-like protein 1 isoform X1",
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        "protein_names_uniprotkb": "Polycystin-1-like protein 1 isoform X1",
        "protein_names_refseq": "polycystin-1-like protein 1 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "gene_names_refseq": "zgc:112146",
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        "protein_name": "Uncharacterized protein",
        "gene_name": "LOC141380659",
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        "gene_names_refseq": "LOC141380659",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "ribonuclease H",
        "gene_name": "LOC141380667",
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        "protein_names_uniprotkb": "ribonuclease H; 3.1.26.4",
        "protein_names_refseq": "uncharacterized protein",
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        "protein_names_uniprotkb": "Actin nucleation-promoting factor WASL; Neural Wiskott-Aldrich syndrome protein",
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        "protein_names_refseq": "metalloreductase STEAP2 isoform X2",
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        "protein_name": "Major histocompatibility complex class I LFA isoform X1",
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        "protein_name": "Coiled-coil domain-containing protein 73 isoform X1",
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        "protein_names_uniprotkb": "Coiled-coil domain-containing protein 73 isoform X1",
        "protein_names_refseq": "coiled-coil domain-containing protein 73 isoform X1",
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        "protein_name": "Uncharacterized protein znf271 isoform X2",
        "gene_name": "znf271",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein znf271 isoform X2",
        "refseq_ac": "XP_073797464",
        "gene_names_uniprotkb": "znf271",
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        "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding",
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        "length": 778,
        "protein_name": "Caldesmon 1b isoform X1",
        "gene_name": "cald1b",
        "organism": "Zebrafish",
        "refseq_name": "caldesmon 1b isoform X1",
        "refseq_ac": "XP_073798240",
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        "gene_names_refseq": "CaD; cald1b; cald1; si:dkey-206m15.7",
        "protein_names_uniprotkb": "Caldesmon 1b isoform X1",
        "protein_names_refseq": "caldesmon 1b isoform X1",
        "tax_id": 7955,
        "disease": "proliferative diabetic retinopathy (Disease Ontology:DOID:13207)",
        "pathway": " (dre:563892)",
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        "protein_name": "Protein fantom isoform X1",
        "gene_name": "rpgrip1",
        "organism": "Zebrafish",
        "refseq_name": "protein fantom isoform X1",
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        "gene_names_uniprotkb": "rpgrip1",
        "gene_names_refseq": "rpgrip1",
        "protein_names_uniprotkb": "Protein fantom isoform X1",
        "protein_names_refseq": "protein fantom isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "non-specific serine/threonine protein kinase",
        "gene_name": "pimr63",
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        "refseq_name": "serine/threonine-protein kinase pim-3-like isoform X1",
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        "protein_names_refseq": "serine/threonine-protein kinase pim-3-like isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "ec_number_list": "2.7.11.1;2.7.11.13;2.7.11.25;2.7.10.1;2.7.11.22;2.7.11.21;2.7.11.17;2.7.12.1;2.7.12.2;2.7.11.24;2.7.10.2;2.7.11.23;2.7.1.150;2.7.11.12;2.7.11.39;2.7.11.11;2.7.1.153;2.7.1.137;2.7.1.154;2.7.11.26;2.7.11.31",
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        "protein_name": "Ankyrin repeat and fibronectin type-III domain-containing protein 1 isoform X1",
        "gene_name": "ankfn1b",
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        "refseq_name": "ankyrin repeat and fibronectin type-III domain-containing protein 1 isoform X1",
        "refseq_ac": "XP_073797221",
        "gene_names_uniprotkb": "ankfn1b",
        "gene_names_refseq": "ankfn1b",
        "protein_names_uniprotkb": "Ankyrin repeat and fibronectin type-III domain-containing protein 1 isoform X1",
        "protein_names_refseq": "ankyrin repeat and fibronectin type-III domain-containing protein 1 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_biological_process": "GO:0007165 signal transduction;GO:0050884 neuromuscular process controlling posture;GO:0001966 thigmotaxis",
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        "protein_name": "Coiled-coil-helix-coiled-coil-helix domain containing 3b isoform X1",
        "gene_name": "chchd3b",
        "organism": "Zebrafish",
        "refseq_name": "coiled-coil-helix-coiled-coil-helix domain containing 3b isoform X1",
        "refseq_ac": "XP_073797899",
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        "gene_names_refseq": "chchd3b; fd08g06; mic19b; wu:fd08g06; zgc:162618",
        "protein_names_uniprotkb": "Coiled-coil-helix-coiled-coil-helix domain containing 3b isoform X1",
        "protein_names_refseq": "coiled-coil-helix-coiled-coil-helix domain containing 3b isoform X1",
        "tax_id": 7955,
        "disease": "hypoplastic left heart syndrome (Disease Ontology:DOID:9955)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_cellular_component": "GO:0061617 MICOS complex",
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        "length": 609,
        "protein_name": "Ferric reductase 1",
        "gene_name": "frrs1b",
        "organism": "Zebrafish",
        "refseq_name": "putative ferric-chelate reductase 1",
        "refseq_ac": "XP_073797018",
        "gene_names_uniprotkb": "frrs1b",
        "gene_names_refseq": "frrs1b",
        "protein_names_uniprotkb": "Ferric reductase 1",
        "protein_names_refseq": "putative ferric-chelate reductase 1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Ferric reductase that reduces Fe(3+) to Fe(2+) and could play a role in iron import into cells. The electron donor and therefore the reaction mechanism are not known., [UniProtKB, UniProtKB]",
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        "protein_name": "Uncharacterized protein",
        "gene_name": "LOC141380723",
        "organism": "Zebrafish",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "length": 111,
        "protein_name": "Chemokine CCL-CUa",
        "gene_name": "LOC100141478",
        "organism": "Zebrafish",
        "refseq_name": "chemokine CCL-CUa precursor",
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        "gene_names_uniprotkb": "LOC100141478",
        "gene_names_refseq": "LOC100141478",
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        "protein_names_refseq": "chemokine CCL-CUa precursor",
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        "function": "##Evidence-Data-START## Transcript exon combination :: EH560557.1, EH539367.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000024.1. On or before Aug 13, 2025 this sequence version replaced XP_073796979.1, NP_001108572.1., [RefSeq]",
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        "record_id": "A0AC58IS06-1",
        "record_type": "protein"
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        "uniprot_canonical_ac": "A0AC58IS07-1",
        "uniprot_id": "A0AC58IS07_DANRE",
        "mass": 99155.0,
        "length": 860,
        "protein_name": "Guanine nucleotide exchange factor VAV3 isoform X1",
        "gene_name": "vav3",
        "organism": "Zebrafish",
        "refseq_name": "guanine nucleotide exchange factor VAV3 isoform X1",
        "refseq_ac": "XP_073797007",
        "gene_names_uniprotkb": "vav3",
        "gene_names_refseq": "vav3",
        "protein_names_uniprotkb": "Guanine nucleotide exchange factor VAV3 isoform X1",
        "protein_names_refseq": "guanine nucleotide exchange factor VAV3 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "record_id": "A0AC58IS07-1",
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        "uniprot_canonical_ac": "A0AC58IS15-1",
        "uniprot_id": "A0AC58IS15_DANRE",
        "mass": 111404.0,
        "length": 1023,
        "protein_name": "Dihydropyrimidine dehydrogenase [NADP(+)]",
        "gene_name": "dpyda",
        "organism": "Zebrafish",
        "refseq_name": "dihydropyrimidine dehydrogenase [NADP(+)] isoform X1",
        "refseq_ac": "XP_073797027",
        "gene_names_uniprotkb": "dpyda",
        "gene_names_refseq": "dpyda",
        "protein_names_uniprotkb": "Dihydropyrimidine dehydrogenase [NADP(+)]; 1.3.1.2; DHPDHase; DPD; Dihydrothymine dehydrogenase; Dihydrouracil dehydrogenase",
        "protein_names_refseq": "dihydropyrimidine dehydrogenase [NADP(+)] isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine., [UniProtKB, UniProtKB, UniProtKB]",
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        "secondary_ac_list": "",
        "ec_number_list": "1.3.1.2",
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        "hit_score": 0.1,
        "record_id": "A0AC58IS15-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58IS20-1",
        "uniprot_id": "A0AC58IS20_DANRE",
        "mass": 104702.0,
        "length": 938,
        "protein_name": "Cilia- and flagella-associated protein 70 isoform X3; Uncharacterized protein isoform X1; Uncharacterized protein isoform X2",
        "gene_name": "LOC141380737",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X2",
        "refseq_ac": "XP_073768614",
        "gene_names_uniprotkb": "LOC141380737; LOC141375313; LOC141376079; LOC141377798; LOC141378823; LOC141379219; LOC141381022; cfap70",
        "gene_names_refseq": "LOC141376079",
        "protein_names_uniprotkb": "Cilia- and flagella-associated protein 70 isoform X3; Uncharacterized protein isoform X1; Uncharacterized protein isoform X2",
        "protein_names_refseq": "uncharacterized protein isoform X2",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0AC58G380;A0AC58GFV3;A0AC58HC77;A0AC58HWR9;A0AC58I2A2;A0AC58IZ21;A0AC58J1A9",
        "ec_number_list": "",
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        "record_id": "A0AC58IS20-1",
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    {
        "uniprot_canonical_ac": "A0AC58IS21-1",
        "uniprot_id": "A0AC58IS21_DANRE",
        "mass": 60900.0,
        "length": 609,
        "protein_name": "Uncharacterized protein",
        "gene_name": "LOC141380733",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": "XP_073797022",
        "gene_names_uniprotkb": "LOC141380733",
        "gene_names_refseq": "LOC141380733",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "protein_name": "Receptor protein-tyrosine kinase",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588715.1837039.1, SRR32588717.4973189.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000024.1. On Aug 13, 2025 this sequence version replaced XP_073797090.1., [RefSeq]",
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        "protein_name": "Matrix metalloproteinase-16 isoform X1",
        "gene_name": "mmp16a",
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        "go_molecular_function": "GO:0008237 metallopeptidase activity",
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        "gene_name": "LOC141380764",
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        "refseq_name": "uncharacterized protein",
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        "gene_names_uniprotkb": "LOC141380764",
        "gene_names_refseq": "LOC141380764",
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        "predicted_glycosites": 0,
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        "gene_names_uniprotkb": "kctd5b",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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    {
        "uniprot_canonical_ac": "A0AC58ISL6-1",
        "uniprot_id": "A0AC58ISL6_DANRE",
        "mass": 25463.0,
        "length": 225,
        "protein_name": "Pentraxin family member",
        "gene_name": "crp5",
        "organism": "Zebrafish",
        "refseq_name": "C-reactive protein precursor",
        "refseq_ac": "NP_001410333",
        "gene_names_uniprotkb": "crp5",
        "gene_names_refseq": "CRP5.1; CRP5.2; crp5; crp; si:ch211-234p6.10; zgc:136389; zgc:152809",
        "protein_names_uniprotkb": "Pentraxin family member",
        "protein_names_refseq": "C-reactive protein precursor; PTX5; PTX; c-reactive protein, pentraxin-related; dare-CRP; dare-PTX; pentraxin fusion protein; pentraxin-related C-reactive protein; short-chain pentraxin",
        "tax_id": 7955,
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        "function": "##Evidence-Data-START## Transcript exon combination :: EH524298.1, CV490373.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476747, SAMEA4476751 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000024.1. On Sep 22, 2025 this sequence version replaced NP_001410333.1. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Crystal of C-reactive protein diffracted to 2.3 A resolution and belonged to space group R3, with unit-cell parameters a = b = 114.7, c = 61.0 A, [RefSeq, PubMed]",
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        "secondary_ac_list": "A0AC58IU15;A0AC58IU20;A0AC58IU29;A0AC58IU30;A0AC58IU32",
        "ec_number_list": "4.3.1.3",
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        "uniprot_canonical_ac": "A0AC58IUN4-1",
        "uniprot_id": "A0AC58IUN4_DANRE",
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        "length": 483,
        "protein_name": "Interleukin-1 receptor-associated kinase 4",
        "gene_name": "irak4",
        "organism": "Zebrafish",
        "refseq_name": "interleukin-1 receptor-associated kinase 4",
        "refseq_ac": "NP_001428777",
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        "gene_names_refseq": "irak4; zgc:55553",
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        "protein_names_refseq": "interleukin-1 receptor-associated kinase 4",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01007893.1, AY616584.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000025.1. On Jul 8, 2025 this sequence version replaced XP_073797945.1. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens., [UniProtKB, UniProtKB]",
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        "secondary_ac_list": "A0AC58IUN6;A0AC58IUP0",
        "ec_number_list": "2.7.11.1;2.7.11.13;2.7.11.25;2.7.10.1;2.7.11.22;2.7.11.21;2.7.11.17;2.7.12.1;2.7.12.2;2.7.11.24;2.7.10.2;2.7.11.23;2.7.1.150;2.7.11.12;2.7.11.39;2.7.11.11;2.7.1.153;2.7.1.137;2.7.1.154;2.7.11.26;2.7.11.31",
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    {
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        "length": 1018,
        "protein_name": "Disintegrin and metalloproteinase domain-containing protein 10",
        "gene_name": "adam10b",
        "organism": "Zebrafish",
        "refseq_name": "",
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        "gene_names_uniprotkb": "adam10b; wu:fc03d12; zgc:64203",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Disintegrin and metalloproteinase domain-containing protein 10; 3.4.24.81; Kuzbanian protein homolog",
        "protein_names_refseq": "",
        "tax_id": 7955,
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        "go_molecular_function": "GO:0008237 metallopeptidase activity",
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    {
        "uniprot_canonical_ac": "A0AC58IV13-1",
        "uniprot_id": "A0AC58IV13_DANRE",
        "mass": 28176.0,
        "length": 253,
        "protein_name": "Beta-actin-like protein 2 isoform X1",
        "gene_name": "acte1",
        "organism": "Zebrafish",
        "refseq_name": "beta-actin-like protein 2 isoform X1",
        "refseq_ac": "XP_073798070",
        "gene_names_uniprotkb": "acte1; actc1c; zgc:86725",
        "gene_names_refseq": "actc1c; acte1; zgc:86725",
        "protein_names_uniprotkb": "Beta-actin-like protein 2 isoform X1",
        "protein_names_refseq": "beta-actin-like protein 2 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA., [UniProtKB, UniProtKB]",
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        "synthesized_glycan_count": 0,
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        "record_id": "A0AC58IV13-1",
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    {
        "uniprot_canonical_ac": "A0AC58IVF6-1",
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        "mass": 24834.0,
        "length": 226,
        "protein_name": "Fanconi anemia core complex-associated protein 24 isoform X1",
        "gene_name": "faap24",
        "organism": "Zebrafish",
        "refseq_name": "Fanconi anemia core complex-associated protein 24 isoform X1",
        "refseq_ac": "XP_073798213",
        "gene_names_uniprotkb": "faap24; zgc:162267",
        "gene_names_refseq": "faap24; zgc:162267",
        "protein_names_uniprotkb": "Fanconi anemia core complex-associated protein 24 isoform X1",
        "protein_names_refseq": "Fanconi anemia core complex-associated protein 24 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "record_id": "A0AC58IVF6-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58IVI6-1",
        "uniprot_id": "A0AC58IVI6_DANRE",
        "mass": 147644.0,
        "length": 1292,
        "protein_name": "Paired amphipathic helix protein Sin3a",
        "gene_name": "sin3aa",
        "organism": "Zebrafish",
        "refseq_name": "SIN3 transcription regulator family member Aa isoform X1",
        "refseq_ac": "XP_073798237",
        "gene_names_uniprotkb": "sin3aa; zgc:162128",
        "gene_names_refseq": "sin3aa; zgc:162128",
        "protein_names_uniprotkb": "Paired amphipathic helix protein Sin3a; Histone deacetylase complex subunit Sin3a; Transcriptional corepressor Sin3a",
        "protein_names_refseq": "SIN3 transcription regulator family member Aa isoform X1",
        "tax_id": 7955,
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        "pathway_count": 0,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in the control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation. Cooperates with FOXK1 to regulate cell cycle progression probably by repressing cell cycle inhibitor genes expression. Required for cortical neuron differentiation and callosal axon elongation., [UniProtKB, UniProtKB]",
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    {
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        "uniprot_id": "A0AC58IVL5_DANRE",
        "mass": 92101.0,
        "length": 843,
        "protein_name": "Furin (Paired basic amino acid cleaving enzyme) b isoform X1",
        "gene_name": "furinb",
        "organism": "Zebrafish",
        "refseq_name": "furin (paired basic amino acid cleaving enzyme) b isoform X1",
        "refseq_ac": "XP_073798271",
        "gene_names_uniprotkb": "furinb",
        "gene_names_refseq": "furinb",
        "protein_names_uniprotkb": "Furin (Paired basic amino acid cleaving enzyme) b isoform X1",
        "protein_names_refseq": "furin (paired basic amino acid cleaving enzyme) b isoform X1",
        "tax_id": 7955,
        "disease": "arteriosclerosis (Disease Ontology:DOID:2349)",
        "pathway": " (dre:566591)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "16678149;18462713;20625388;23935514;24178295;34622921;34784297;36017776;37014912;37629102",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0004252 serine-type endopeptidase activity",
        "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005802 trans-Golgi network",
        "go_biological_process": "GO:0016486 peptide hormone processing;GO:0051216 cartilage development;GO:0035622 intrahepatic bile duct development",
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    {
        "uniprot_canonical_ac": "A0AC58IW39-1",
        "uniprot_id": "A0AC58IW39_DANRE",
        "mass": 64890.0,
        "length": 581,
        "protein_name": "Adenosylhomocysteinase",
        "gene_name": "ahcyl2a",
        "organism": "Zebrafish",
        "refseq_name": "adenosylhomocysteinase like 2a isoform X1",
        "refseq_ac": "XP_073798445",
        "gene_names_uniprotkb": "ahcyl2a; zgc:158222",
        "gene_names_refseq": "ahcyl2a; zgc:158222",
        "protein_names_uniprotkb": "Adenosylhomocysteinase; 3.13.2.1",
        "protein_names_refseq": "adenosylhomocysteinase like 2a isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:791167)",
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        "publication_id_list": "27189481;28252024;29213239;37256068",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "secondary_ac_list": "",
        "ec_number_list": "3.13.2.1",
        "go_molecular_function": "GO:0004013 adenosylhomocysteinase activity;GO:0016787 hydrolase activity",
        "go_cellular_component": "GO:0005829 cytosol",
        "go_biological_process": "GO:0006730 one-carbon metabolic process;GO:0033353 S-adenosylmethionine cycle",
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        "protein_name": "Coiled-coil domain-containing protein 33 isoform X1",
        "gene_name": "ccdc33",
        "organism": "Zebrafish",
        "refseq_name": "",
        "refseq_ac": "",
        "gene_names_uniprotkb": "ccdc33",
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        "protein_names_uniprotkb": "Coiled-coil domain-containing protein 33 isoform X1",
        "protein_names_refseq": "",
        "tax_id": 7955,
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        "pathway": " (dre:553442)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395017.408869.1, SRR26395017.751640.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000025.1. On Jun 10, 2025 this sequence version replaced NP_001119902.1., [RefSeq]",
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        "gene_name": "epx",
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        "disease": "lupus nephritis (Disease Ontology:DOID:0080162); Alzheimer's disease 1 (Disease Ontology:DOID:0080348); cardiovascular system disease (Disease Ontology:DOID:1287); lung cancer (Disease Ontology:DOID:1324); cystic fibrosis (Disease Ontology:DOID:1485); renovascular hypertension (Disease Ontology:DOID:1591); keratosis (Disease Ontology:DOID:161); cystitis (Disease Ontology:DOID:1679); pancreatic cancer (Disease Ontology:DOID:1793); asthma (Disease Ontology:DOID:2841); glomerulonephritis (Disease Ontology:DOID:2921); acute kidney failure (Disease Ontology:DOID:3021); interstitial lung disease (Disease Ontology:DOID:3082); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); liver cirrhosis (Disease Ontology:DOID:5082); hepatocellular carcinoma (Disease Ontology:DOID:684); end stage renal disease (Disease Ontology:DOID:783); lung disease (Disease Ontology:DOID:850); vasculitis (Disease Ontology:DOID:865); bacterial pneumonia (Disease Ontology:DOID:874); status asthmaticus (Disease Ontology:DOID:9362)",
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        "protein_name": "Solute carrier family 15 member 5",
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        "protein_names_uniprotkb": "Solute carrier family 15 member 5",
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        "protein_name": "Zinc finger protein 800a isoform X1",
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        "protein_names_uniprotkb": "Zinc finger protein 800a isoform X1",
        "protein_names_refseq": "zinc finger protein 800a isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Carbonic anhydrase",
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        "organism": "Zebrafish",
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        "gene_names_uniprotkb": "ca12",
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        "protein_names_refseq": "carbonic anhydrase 12 isoform X1",
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        "protein_name": "Tripartite motif-containing protein 44 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "NAD(P)H oxidase (H2O2-forming)",
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        "protein_names_uniprotkb": "NAD(P)H oxidase (H2O2-forming); 1.6.3.1",
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        "tax_id": 7955,
        "disease": "congenital hypothyroidism (Disease Ontology:DOID:0050328); primary bacterial infectious disease (Disease Ontology:DOID:0050338); thyroid dyshormonogenesis 6 (Disease Ontology:DOID:0112189); hypothyroidism (Disease Ontology:DOID:1459); cholera (Disease Ontology:DOID:1498); ulcerative colitis (Disease Ontology:DOID:8577); Crohn's disease (Disease Ontology:DOID:8778); phenylketonuria (Disease Ontology:DOID:9281)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_biological_process": "GO:0030878 thyroid gland development;GO:0006952 defense response;GO:0006979 response to oxidative stress;GO:0002523 leukocyte migration involved in inflammatory response;GO:0009617 response to bacterium",
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        "protein_name": "Transporter",
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        "refseq_name": "sodium- and chloride-dependent GABA transporter 2 isoform X1",
        "refseq_ac": "XP_073798676",
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        "gene_names_refseq": "slc6a13",
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        "tax_id": 7955,
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        "protein_name": "Interleukin-17 receptor A isoform X1",
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        "protein_names_refseq": "interleukin-17 receptor A isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IW84-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58IW93-1",
        "uniprot_id": "A0AC58IW93_DANRE",
        "mass": 55879.0,
        "length": 478,
        "protein_name": "Integrase core domain-containing protein",
        "gene_name": "LOC141380841",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": "XP_073798491",
        "gene_names_uniprotkb": "LOC141380841",
        "gene_names_refseq": "LOC141380841",
        "protein_names_uniprotkb": "Integrase core domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
        "total_reported_o_glycosites": 0,
        "total_reported_c_glycosites": 0,
        "total_reported_s_glycosites": 0,
        "total_n_glycosites": 0,
        "total_o_glycosites": 0,
        "total_c_glycosites": 0,
        "total_s_glycosites": 0,
        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58IW93-1",
        "record_type": "protein"
    }
]
