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        "gene_name": "lhb",
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        "refseq_name": "lutropin subunit beta isoform X1",
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        "gene_names_refseq": "lhb1; lhbeta1; lhb; zgc:92312",
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        "protein_names_refseq": "lutropin subunit beta isoform X1",
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        "protein_name": "B-cell linker protein isoform X1",
        "gene_name": "blnk",
        "organism": "Zebrafish",
        "refseq_name": "B-cell linker protein isoform X1",
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        "gene_names_refseq": "blnk",
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        "protein_names_refseq": "B-cell linker protein isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Amino acid transporter",
        "gene_name": "slc1a8b",
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        "protein_names_uniprotkb": "Amino acid transporter",
        "protein_names_refseq": "solute carrier family 1 member 8b isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Leucine-rich repeat-containing protein 1 isoform X1",
        "gene_name": "lrrc1",
        "organism": "Zebrafish",
        "refseq_name": "",
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        "gene_names_uniprotkb": "lrrc1; zgc:101523",
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        "protein_names_uniprotkb": "Leucine-rich repeat-containing protein 1 isoform X1",
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        "secondary_ac_list": "A0AC58H0Z0",
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    {
        "uniprot_canonical_ac": "A0AC58H0Z2-1",
        "uniprot_id": "A0AC58H0Z2_DANRE",
        "mass": 58921.0,
        "length": 518,
        "protein_name": "DNA-directed DNA/RNA polymerase mu",
        "gene_name": "dntt",
        "organism": "Zebrafish",
        "refseq_name": "DNA nucleotidylexotransferase isoform X1",
        "refseq_ac": "XP_073775652",
        "gene_names_uniprotkb": "dntt; TdT",
        "gene_names_refseq": "TdT; dntt",
        "protein_names_uniprotkb": "DNA-directed DNA/RNA polymerase mu; 2.7.7.7",
        "protein_names_refseq": "DNA nucleotidylexotransferase isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ)., [UniProtKB, UniProtKB]",
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        "ec_number_list": "2.7.7.7;2.7.7.31;2.7.7.49;3.6.4.12;2.7.7.102;4.2.99.18;4.2.99.-",
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        "uniprot_id": "A0AC58H4F1_DANRE",
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        "length": 366,
        "protein_name": "non-specific serine/threonine protein kinase",
        "gene_name": "pimr47",
        "organism": "Zebrafish",
        "refseq_name": "serine/threonine-protein kinase pim-3 isoform X1",
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        "protein_names_refseq": "serine/threonine-protein kinase pim-3 isoform X1",
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        "ec_number_list": "2.7.11.1;2.7.11.13;2.7.11.25;2.7.10.1;2.7.11.22;2.7.11.21;2.7.11.17;2.7.12.1;2.7.12.2;2.7.11.24;2.7.10.2;2.7.11.23;2.7.1.150;2.7.11.12;2.7.11.39;2.7.11.11;2.7.1.153;2.7.1.137;2.7.1.154;2.7.11.26;2.7.11.31",
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        "protein_name": "Ninein isoform X1",
        "gene_name": "nin",
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        "gene_names_uniprotkb": "nin",
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        "protein_names_uniprotkb": "Ninein isoform X1",
        "protein_names_refseq": "ninein isoform X1",
        "tax_id": 7955,
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        "go_molecular_function": "GO:0005509 calcium ion binding",
        "go_cellular_component": "GO:0005813 centrosome;GO:0005874 microtubule",
        "go_biological_process": "GO:0030917 midbrain-hindbrain boundary development;GO:0001841 neural tube formation",
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    },
    {
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        "uniprot_id": "A0AC58H474_DANRE",
        "mass": 233201.0,
        "length": 2124,
        "protein_name": "Centrosome-associated protein ALMS1 isoform X1",
        "gene_name": "alms1",
        "organism": "Zebrafish",
        "refseq_name": "ALMS1 centrosome and basal body associated protein isoform 1",
        "refseq_ac": "NP_001429403",
        "gene_names_uniprotkb": "alms1",
        "gene_names_refseq": "alms1; fe01b06; si:ch211-243o19.5; si:dkey-265c15.2; wu:fe01b06",
        "protein_names_uniprotkb": "Centrosome-associated protein ALMS1 isoform X1",
        "protein_names_refseq": "ALMS1 centrosome and basal body associated protein isoform 1; Alstrom syndrome 1; Alstrom syndrome protein 1 homolog; Alstrom syndrome protein 1; serine-rich adhesin for platelets",
        "tax_id": 7955,
        "disease": "Alstrom syndrome (Disease Ontology:DOID:0050473); type 2 diabetes mellitus (Disease Ontology:DOID:9352); obesity (Disease Ontology:DOID:9970)",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395028.392614.1, SRR32588722.3513239.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA898400, SAMN18715719 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. On Aug 8, 2025 this sequence version replaced XP_073776788.1., [RefSeq]; Alms1 loss-of-function zebrafish mutant demonstrates conservation of hallmark clinical characteristics alongside metabolic syndrome phenotypes, including a propensity for obesity and fatty livers, hyperinsulinemia and glucose response defects. These observations support the alms1 loss-of-function zebrafish mutant as a monogenic model for mechanistic interrogation of type 2 diabetes mellitus phenotypes., [RefSeq, PubMed]; Alms1 mutant zebrafish do not show hair cell phenotypes seen in other cilia mutants. Publication Status: Online-Only, [RefSeq, PubMed]",
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        "go_cellular_component": "GO:0005813 centrosome;GO:0005829 cytosol;GO:0005814 centriole",
        "go_biological_process": "GO:1990798 pancreas regeneration;GO:0009887 animal organ morphogenesis;GO:0046599 regulation of centriole replication;GO:0044342 type B pancreatic cell proliferation",
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        "length": 275,
        "protein_name": "Tetraspanin",
        "gene_name": "tspan14",
        "organism": "Zebrafish",
        "refseq_name": "tetraspanin-14 isoform X1",
        "refseq_ac": "XP_073776075",
        "gene_names_uniprotkb": "tspan14; zgc:153613",
        "gene_names_refseq": "tspan14; zgc:153613",
        "protein_names_uniprotkb": "Tetraspanin",
        "protein_names_refseq": "tetraspanin-14 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_cellular_component": "GO:0005886 plasma membrane",
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        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "si:dkey-192p21.6",
        "organism": "Zebrafish",
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        "refseq_ac": "XP_073775879",
        "gene_names_uniprotkb": "si:dkey-192p21.6",
        "gene_names_refseq": "si:dkey-192p21.6",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
        "disease": "retinitis pigmentosa 73 (Disease Ontology:DOID:0110389); mucopolysaccharidosis type IIIC (Disease Ontology:DOID:0111393)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "KH domain-containing RNA-binding protein QKI isoform X1",
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        "refseq_ac": "XP_073776633",
        "gene_names_uniprotkb": "qkib",
        "gene_names_refseq": "qkib",
        "protein_names_uniprotkb": "KH domain-containing RNA-binding protein QKI isoform X1",
        "protein_names_refseq": "KH domain-containing RNA-binding protein QKI isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "go_molecular_function": "GO:0003730 mRNA 3'-UTR binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm",
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        "uniprot_id": "A0AC58H1V2_DANRE",
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        "length": 907,
        "protein_name": "Prominin 1 b isoform X1",
        "gene_name": "prom1b",
        "organism": "Zebrafish",
        "refseq_name": "prominin 1 b isoform X1",
        "refseq_ac": "XP_073775965",
        "gene_names_uniprotkb": "prom1b; proml2",
        "gene_names_refseq": "prom1b; proml2",
        "protein_names_uniprotkb": "Prominin 1 b isoform X1",
        "protein_names_refseq": "prominin 1 b isoform X1",
        "tax_id": 7955,
        "disease": "retinal macular dystrophy 2 (Disease Ontology:DOID:0070517); retinitis pigmentosa 41 (Disease Ontology:DOID:0110376); cone-rod dystrophy 12 (Disease Ontology:DOID:0111019); retinal degeneration (Disease Ontology:DOID:8466); diabetes mellitus (Disease Ontology:DOID:9351)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_cellular_component": "GO:0016324 apical plasma membrane;GO:0031528 microvillus membrane",
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        "protein_name": "Centrosomal protein of 170 kDa isoform X1",
        "gene_name": "cep170aa",
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        "refseq_name": "centrosomal protein of 170 kDa isoform X1",
        "refseq_ac": "XP_073776820",
        "gene_names_uniprotkb": "cep170aa",
        "gene_names_refseq": "cep170aa",
        "protein_names_uniprotkb": "Centrosomal protein of 170 kDa isoform X1",
        "protein_names_refseq": "centrosomal protein of 170 kDa isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "5-hydroxytryptamine receptor 1D isoform X1",
        "gene_name": "LOC101886918",
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        "gene_names_uniprotkb": "LOC101886918",
        "gene_names_refseq": "LOC101886918",
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        "protein_names_refseq": "5-hydroxytryptamine receptor 1D isoform X1",
        "tax_id": 7955,
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        "go_molecular_function": "GO:0004930 G protein-coupled receptor activity",
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        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC101886518",
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        "refseq_name": "uncharacterized protein isoform X1",
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        "gene_names_uniprotkb": "LOC101886518",
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        "tax_id": 7955,
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        "protein_name": "Uncharacterized protein si:ch73-105b23.6 isoform X1",
        "gene_name": "si:ch73-105b23.6",
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        "gene_names_refseq": "si:ch73-105b23.6",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "go_molecular_function": "GO:0005509 calcium ion binding",
        "go_cellular_component": "GO:0016020 membrane;GO:0071944 cell periphery",
        "go_biological_process": "GO:0007160 cell-matrix adhesion;GO:0003181 atrioventricular valve morphogenesis",
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        "length": 863,
        "protein_name": "Vitrin",
        "gene_name": "vit",
        "organism": "Zebrafish",
        "refseq_name": "vitrin isoform X1",
        "refseq_ac": "XP_073776524",
        "gene_names_uniprotkb": "vit",
        "gene_names_refseq": "vit",
        "protein_names_uniprotkb": "Vitrin",
        "protein_names_refseq": "vitrin isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Promotes matrix assembly and cell adhesiveness. Plays a role in spinal cord formation by regulating the proliferation and differentiation of neural stem cells., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_biological_process": "GO:0007399 nervous system development;GO:0007601 visual perception",
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        "protein_name": "PHD finger protein 3 isoform X1",
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        "protein_names_refseq": "PHD finger protein 3 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "GO:0008270 zinc ion binding",
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        "length": 475,
        "protein_name": "Threonine aspartase 1",
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        "refseq_ac": "XP_073775918",
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        "gene_names_refseq": "si:dkey-38k3.3; tasp1",
        "protein_names_uniprotkb": "Threonine aspartase 1",
        "protein_names_refseq": "threonine aspartase 1 isoform X1",
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        "pathway": " (dre:566980);  (R-DRE-9772755)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "GO:0004298 threonine-type endopeptidase activity",
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        "gene_names_uniprotkb": "wdr27",
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        "tax_id": 7955,
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        "protein_name": "adenylate cyclase",
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        "protein_name": "C2H2-type domain-containing protein",
        "gene_name": "si:dkeyp-2e4.3",
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        "gene_names_refseq": "si:dkeyp-2e4.3",
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        "protein_names_refseq": "uncharacterized protein LOC100002257",
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        "protein_name": "Signal-induced proliferation-associated 1-like protein 2 isoform X1",
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        "protein_name": "Uncharacterized protein",
        "gene_name": "LOC110440166",
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        "length": 1890,
        "protein_name": "ribonuclease H",
        "gene_name": "LOC141377075",
        "organism": "Zebrafish",
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        "protein_name": "Potassium channel subfamily K member 12 isoform X1",
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        "go_biological_process": "GO:0034220 monoatomic ion transmembrane transport",
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        "gene_name": "foxn2a",
        "organism": "Zebrafish",
        "refseq_name": "forkhead box protein N2",
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        "uniprot_id": "A0AC58H3I4_DANRE",
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        "length": 8238,
        "protein_name": "Dystonin",
        "gene_name": "dst",
        "organism": "Zebrafish",
        "refseq_name": "dystonin isoform X1",
        "refseq_ac": "XP_073776543",
        "gene_names_uniprotkb": "dst",
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        "protein_names_uniprotkb": "Dystonin; Bullous pemphigoid antigen 1; Dystonia musculorum protein; Hemidesmosomal plaque protein",
        "protein_names_refseq": "dystonin isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hemidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional mesh. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport. Mediates docking of the dynein/dynactin motor complex to vesicle cargos for retrograde axonal transport through its interaction with TMEM108 and DCTN1., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Plays a structural role in the assembly of hemidesmosomes of epithelial cells; anchors keratin-containing intermediate filaments to the inner plaque of hemidesmosomes. Required for the regulation of keratinocyte polarity and motility; mediates integrin ITGB4 regulation of RAC1 activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Required for bundling actin filaments around the nucleus., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "protein_name": "GTP-binding protein 2",
        "gene_name": "gtpbp2a",
        "organism": "Zebrafish",
        "refseq_name": "GTP-binding protein 2",
        "refseq_ac": "XP_073776602",
        "gene_names_uniprotkb": "gtpbp2a",
        "gene_names_refseq": "gtpbp2a",
        "protein_names_uniprotkb": "GTP-binding protein 2",
        "protein_names_refseq": "GTP-binding protein 2",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395012.838825.1, SRR32588732.15700326.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. On Aug 21, 2025 this sequence version replaced XP_073776617.1., [RefSeq]",
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        "protein_name": "Exportin-5",
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        "protein_names_refseq": "uncharacterized protein si:ch73-193i2.2",
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        "secondary_ac_list": "A0AC58H3R6",
        "ec_number_list": "2.7.11.1;1.5.1.2",
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        "protein_name": "Uncharacterized protein si:ch211-130h14.4 isoform X1",
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        "protein_name": "Equilibrative nucleoside transporter 3",
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        "protein_name": "CUB and sushi domain-containing protein 1",
        "gene_name": "LOC101885457",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "gene_names_refseq": "id:ibd5135; si:ch211-93n23.6; ttc7a",
        "protein_names_uniprotkb": "Tetratricopeptide repeat protein 7A",
        "protein_names_refseq": "tetratricopeptide repeat protein 7A",
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        "protein_name": "Myomesin-2 isoform X1",
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        "refseq_name": "myomesin-2 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Reverse transcriptase domain-containing protein",
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        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
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        "gene_names_refseq": "LOC141377116",
        "protein_names_uniprotkb": "Reverse transcriptase domain-containing protein",
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        "protein_name": "Serine protease HTRA2, mitochondrial-like isoform X1",
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        "refseq_name": "serine protease HTRA2, mitochondrial-like isoform X1",
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        "gene_names_refseq": "LOC141377125",
        "protein_names_uniprotkb": "Serine protease HTRA2, mitochondrial-like isoform X1",
        "protein_names_refseq": "serine protease HTRA2, mitochondrial-like isoform X1",
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        "protein_name": "non-specific serine/threonine protein kinase",
        "gene_name": "pimr161",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "uniprot_id": "A0AC58H463_DANRE",
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        "length": 303,
        "protein_name": "Epithelial cell adhesion molecule",
        "gene_name": "epcam",
        "organism": "Zebrafish",
        "refseq_name": "epithelial cell adhesion molecule precursor",
        "refseq_ac": "NP_001017593",
        "gene_names_uniprotkb": "epcam",
        "gene_names_refseq": "epcam; sb:cb6; tacstd; wu:fj17g02; zgc:110304; zgc:77119",
        "protein_names_uniprotkb": "Epithelial cell adhesion molecule",
        "protein_names_refseq": "epithelial cell adhesion molecule precursor; pan-epithelial glycoprotein; tumor-associated calcium signal transducer",
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        "function": "##Evidence-Data-START## Transcript exon combination :: BC092861.1, SRR32588715.1291819.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476787, SAMEA708828 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. On or before Sep 23, 2025 this sequence version replaced XP_073776759.1, NP_001017593.1. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; EpCAM acts as a partner of E-cadherin to control adhesiveness and integrity as well as plasticity and morphogenesis within simple epithelia, [RefSeq, PubMed]; Heterogeneously expressed in migrating cells of zebrafish lateral line, [RefSeq, PubMed]",
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        "protein_name": "Serine protease HTRA2, mitochondrial-like",
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        "protein_name": "Serine protease HTRA2, mitochondrial isoform X2",
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        "refseq_ac": "XP_073776769",
        "gene_names_uniprotkb": "si:busm1-sl7.7",
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        "go_molecular_function": "GO:0008233 peptidase activity",
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        "ec_number_list": "2.7.11.1;2.7.11.13;2.7.11.25;2.7.10.1;2.7.11.22;2.7.11.21;2.7.11.17;2.7.12.1;2.7.12.2;2.7.11.24;2.7.10.2;2.7.11.23;2.7.1.150;2.7.11.12;2.7.11.39;2.7.11.11;2.7.1.153;2.7.1.137;2.7.1.154;2.7.11.26;2.7.11.31",
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        "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RNF4 isoform X1",
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        "protein_name": "Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1",
        "gene_name": "arap3",
        "organism": "Zebrafish",
        "refseq_name": "arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1",
        "refseq_ac": "XP_073777974",
        "gene_names_uniprotkb": "arap3",
        "gene_names_refseq": "arap3",
        "protein_names_uniprotkb": "Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1",
        "protein_names_refseq": "arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:558931);  (R-DRE-8980692);  (R-DRE-9013148);  (R-DRE-9013149);  (R-DRE-9013423)",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008270 zinc ion binding",
        "go_cellular_component": "GO:0005737 cytoplasm",
        "go_biological_process": "GO:0007165 signal transduction;GO:0032956 regulation of actin cytoskeleton organization;GO:0001946 lymphangiogenesis",
        "synthesized_glycan_count": 0,
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        "record_type": "protein"
    },
    {
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        "uniprot_id": "A0AC58H5G9_DANRE",
        "mass": 85682.0,
        "length": 752,
        "protein_name": "Relaxin receptor 1 isoform X1",
        "gene_name": "rxfp1",
        "organism": "Zebrafish",
        "refseq_name": "relaxin receptor 1 isoform X1",
        "refseq_ac": "XP_073777221",
        "gene_names_uniprotkb": "rxfp1",
        "gene_names_refseq": "rxfp1",
        "protein_names_uniprotkb": "Relaxin receptor 1 isoform X1",
        "protein_names_refseq": "relaxin receptor 1 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100498669);  (R-DRE-444821)",
        "pathway_count": 2,
        "publication_count": 5,
        "publication_id_list": "21158758;23008798;27189481;28926587;30703485",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "ec_number_list": "",
        "go_molecular_function": "GO:0008528 G protein-coupled peptide receptor activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0009755 hormone-mediated signaling pathway",
        "synthesized_glycan_count": 0,
        "hit_score": 0.6,
        "record_id": "A0AC58H5G9-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58H682-1",
        "uniprot_id": "A0AC58H682_DANRE",
        "mass": 45903.0,
        "length": 403,
        "protein_name": "BSCL2 lipid droplet biogenesis associated, seipin, like isoform X1",
        "gene_name": "bscl2l",
        "organism": "Zebrafish",
        "refseq_name": "BSCL2 lipid droplet biogenesis associated, seipin, like isoform X1",
        "refseq_ac": "XP_073777494",
        "gene_names_uniprotkb": "bscl2l; zgc:110829",
        "gene_names_refseq": "bscl2l; zgc:110829",
        "protein_names_uniprotkb": "BSCL2 lipid droplet biogenesis associated, seipin, like isoform X1",
        "protein_names_refseq": "BSCL2 lipid droplet biogenesis associated, seipin, like isoform X1",
        "tax_id": 7955,
        "disease": "congenital generalized lipodystrophy (Disease Ontology:DOID:0050585); autosomal dominant distal hereditary motor neuronopathy 13 (Disease Ontology:DOID:0081401); hereditary spastic paraplegia 17 (Disease Ontology:DOID:0110770); congenital generalized lipodystrophy type 2 (Disease Ontology:DOID:0111136); male infertility (Disease Ontology:DOID:12336); azoospermia (Disease Ontology:DOID:14227); hereditary spastic paraplegia (Disease Ontology:DOID:2476); lipodystrophy (Disease Ontology:DOID:811)",
        "pathway": "",
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "ec_number_list": "",
        "go_molecular_function": "",
        "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane",
        "go_biological_process": "GO:0006629 lipid metabolic process;GO:0140042 lipid droplet formation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58H682-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58H7M1-1",
        "uniprot_id": "A0AC58H7M1_DANRE",
        "mass": 136254.0,
        "length": 1238,
        "protein_name": "Protocadherin-11 X-linked isoform X1",
        "gene_name": "pcdh11",
        "organism": "Zebrafish",
        "refseq_name": "protocadherin-11 X-linked isoform X1",
        "refseq_ac": "XP_073777978",
        "gene_names_uniprotkb": "pcdh11",
        "gene_names_refseq": "pcdh11",
        "protein_names_uniprotkb": "Protocadherin-11 X-linked isoform X1",
        "protein_names_refseq": "protocadherin-11 X-linked isoform X1",
        "tax_id": 7955,
        "disease": "prostate cancer (Disease Ontology:DOID:10283); cancer (Disease Ontology:DOID:162)",
        "pathway": " (dre:100333121)",
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Potential calcium-dependent cell-adhesion protein., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "biomarker_type": "",
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        "secondary_ac_list": "A0AC58H7M3",
        "ec_number_list": "",
        "go_molecular_function": "GO:0005509 calcium ion binding;GO:0050839 cell adhesion molecule binding",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0007155 cell adhesion;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0009653 anatomical structure morphogenesis",
        "synthesized_glycan_count": 0,
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        "record_id": "A0AC58H7M1-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58H6R0-1",
        "uniprot_id": "A0AC58H6R0_DANRE",
        "mass": 46033.0,
        "length": 411,
        "protein_name": "P2X purinoceptor",
        "gene_name": "p2rx3a",
        "organism": "Zebrafish",
        "refseq_name": "P2X purinoceptor 3a isoform X1",
        "refseq_ac": "XP_073777676",
        "gene_names_uniprotkb": "p2rx3a; fb99b08; p2rx3; p2x3; wu:fb99b08; zP2X3; zfP2X3",
        "gene_names_refseq": "fb99b08; p2rx3a; p2rx3; p2x3; wu:fb99b08; zP2X3; zfP2X3",
        "protein_names_uniprotkb": "P2X purinoceptor; P2X purinoceptor 3",
        "protein_names_refseq": "P2X purinoceptor 3a isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:58147)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "14580944;16413125;17868657;18755773;18850305;25255244;27189481;28710541;30631305;34234366",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Extracellular ATP-activated non-selective cation channel. Plays particularly important role in sensory neurons where its activation is critical for gustatory, nociceptive responses, visceral reflexes and sensory hypersensitization., [UniProtKB, UniProtKB, UniProtKB]; Receptor for ATP that acts as a ligand-gated ion channel., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
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        "missing_score": 10000,
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        "secondary_ac_list": "",
        "ec_number_list": "2.7.11.1;1.5.1.2",
        "go_molecular_function": "GO:0005524 ATP binding;GO:0001614 purinergic nucleotide receptor activity;GO:0004931 extracellularly ATP-gated monoatomic cation channel activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0098794 postsynapse",
        "go_biological_process": "GO:0006812 monoatomic cation transport;GO:0022008 neurogenesis;GO:0033198 response to ATP",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0AC58H6R0-1",
        "record_type": "protein"
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    {
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        "uniprot_id": "A0AC58H7L7_DANRE",
        "mass": 170461.0,
        "length": 1490,
        "protein_name": "Gypsy retrotransposon integrase-like protein 1",
        "gene_name": "LOC137487592",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073777976",
        "gene_names_uniprotkb": "LOC137487592",
        "gene_names_refseq": "LOC137487592",
        "protein_names_uniprotkb": "Gypsy retrotransposon integrase-like protein 1; 2.7.7.49; 3.1.26.4",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:137487592)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "GO:0003964 RNA-directed DNA polymerase activity;GO:0008270 zinc ion binding;GO:0003676 nucleic acid binding;GO:0004523 RNA-DNA hybrid ribonuclease activity;GO:0004190 aspartic-type endopeptidase activity",
        "go_cellular_component": "",
        "go_biological_process": "GO:0006508 proteolysis;GO:0015074 DNA integration",
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        "record_type": "protein"
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    {
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        "uniprot_id": "A0AC58H7J0_DANRE",
        "mass": 83051.0,
        "length": 727,
        "protein_name": "Rho guanine nucleotide exchange factor 37 isoform X1",
        "gene_name": "arhgef37",
        "organism": "Zebrafish",
        "refseq_name": "rho guanine nucleotide exchange factor 37 isoform X1",
        "refseq_ac": "XP_073777949",
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        "protein_names_uniprotkb": "Fibroblast growth factor; FGF",
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        "protein_name": "Four and a half LIM domains protein 1",
        "gene_name": "fhl1a",
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        "refseq_name": "four and a half LIM domains protein 1a isoform X1",
        "refseq_ac": "XP_073777386",
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        "gene_names_refseq": "fhl1a; fhla; fhl; zgc:92025",
        "protein_names_uniprotkb": "Four and a half LIM domains protein 1",
        "protein_names_refseq": "four and a half LIM domains protein 1a isoform X1",
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        "length": 383,
        "protein_name": "Interleukin-12 subunit beta",
        "gene_name": "il12ba",
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        "refseq_name": "interleukin 12Ba precursor isoform X1",
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        "gene_names_refseq": "IL-12 p40; il12ba; il12b; il12p40.b; zgc:152789",
        "protein_names_uniprotkb": "Interleukin-12 subunit beta; Cytotoxic lymphocyte maturation factor 40 kDa subunit; IL-12 subunit p40; IL-12B",
        "protein_names_refseq": "interleukin 12Ba precursor isoform X1",
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        "protein_name": "Hairy-related 11 isoform X1",
        "gene_name": "her11",
        "organism": "Zebrafish",
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        "gene_names_refseq": "her11; him",
        "protein_names_uniprotkb": "Hairy-related 11 isoform X1",
        "protein_names_refseq": "hairy-related 11 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "record_id": "A0AC58H641-1",
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    {
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        "uniprot_id": "A0AC58H6A9_DANRE",
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        "length": 316,
        "protein_name": "COP9 signalosome complex subunit 6",
        "gene_name": "cops6",
        "organism": "Zebrafish",
        "refseq_name": "COP9 signalosome complex subunit 6 isoform X1",
        "refseq_ac": "XP_073777517",
        "gene_names_uniprotkb": "cops6; zgc:112075",
        "gene_names_refseq": "cops6; zgc:112075",
        "protein_names_uniprotkb": "COP9 signalosome complex subunit 6",
        "protein_names_refseq": "COP9 signalosome complex subunit 6 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes., [UniProtKB, UniProtKB]",
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        "length": 395,
        "protein_name": "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating",
        "gene_name": "nsdhl",
        "organism": "Zebrafish",
        "refseq_name": "sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating isoform X1",
        "refseq_ac": "XP_073777512",
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        "gene_names_refseq": "nsdhl; zgc:112474",
        "protein_names_uniprotkb": "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; 1.1.1.170",
        "protein_names_refseq": "sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating isoform X1",
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    {
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        "mass": 33129.0,
        "length": 297,
        "protein_name": "Caspase-3",
        "gene_name": "casp3b",
        "organism": "Zebrafish",
        "refseq_name": "caspase-3b isoform X1",
        "refseq_ac": "XP_073777626",
        "gene_names_uniprotkb": "casp3b; casp3l",
        "gene_names_refseq": "casp3b; casp3l",
        "protein_names_uniprotkb": "Caspase-3; 3.4.22.56",
        "protein_names_refseq": "caspase-3b isoform X1",
        "tax_id": 7955,
        "disease": "stroke (Disease Ontology:DOID:0051061); pre-malignant neoplasm (Disease Ontology:DOID:0060071); brain glioma (Disease Ontology:DOID:0060108); Parkinsonism (Disease Ontology:DOID:0080855); acute necrotizing pancreatitis (Disease Ontology:DOID:0080998); traumatic brain injury (Disease Ontology:DOID:0081292); endometritis (Disease Ontology:DOID:1002); prostate cancer (Disease Ontology:DOID:10283); stomach cancer (Disease Ontology:DOID:10534); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); gastric ulcer (Disease Ontology:DOID:10808); urinary bladder cancer (Disease Ontology:DOID:11054); cryptorchidism (Disease Ontology:DOID:11383); heart disease (Disease Ontology:DOID:114); sciatic neuropathy (Disease Ontology:DOID:11446); bronchopulmonary dysplasia (Disease Ontology:DOID:11650); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); spermatic cord torsion (Disease Ontology:DOID:11996); Huntington's disease (Disease Ontology:DOID:12858); dilated cardiomyopathy (Disease Ontology:DOID:12930); Parkinson's disease (Disease Ontology:DOID:14330); alcohol use disorder (Disease Ontology:DOID:1574); breast cancer (Disease Ontology:DOID:1612); status epilepticus (Disease Ontology:DOID:1824); impotence (Disease Ontology:DOID:1875); atherosclerosis (Disease Ontology:DOID:1936); colon cancer (Disease Ontology:DOID:219); transient cerebral ischemia (Disease Ontology:DOID:224); transitional cell carcinoma (Disease Ontology:DOID:2671); severe acute respiratory syndrome (Disease Ontology:DOID:2945); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); breast carcinoma (Disease Ontology:DOID:3459); middle cerebral artery infarction (Disease Ontology:DOID:3525); intermittent claudication (Disease Ontology:DOID:3669); lung non-small cell carcinoma (Disease Ontology:DOID:3908); cervical cancer (Disease Ontology:DOID:4362); renal cell carcinoma (Disease Ontology:DOID:4450); pancreatitis (Disease Ontology:DOID:4989); ureteral obstruction (Disease Ontology:DOID:5199); intestinal disease (Disease Ontology:DOID:5295); kidney disease (Disease Ontology:DOID:557); retinal disease (Disease Ontology:DOID:5679); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); hepatocellular carcinoma (Disease Ontology:DOID:684); abdominal aortic aneurysm (Disease Ontology:DOID:7693); hyperthyroidism (Disease Ontology:DOID:7998); cataract (Disease Ontology:DOID:83); osteoarthritis (Disease Ontology:DOID:8398); diabetic retinopathy (Disease Ontology:DOID:8947); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352); acute myocardial infarction (Disease Ontology:DOID:9408); diabetic neuropathy (Disease Ontology:DOID:9743); type 1 diabetes mellitus (Disease Ontology:DOID:9744)",
        "pathway": " (dre:566604)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "16888647;19265122;22213104;22546086;23921180;37106740;37256068;38042913;39141879;39165716",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "CD40 ligand isoform X1",
        "gene_name": "cd40lg",
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        "length": 374,
        "protein_name": "Arrestin-C",
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        "protein_names_uniprotkb": "Arrestin-C; Cone arrestin",
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        "protein_name": "LOW QUALITY PROTEIN: uncharacterized protein",
        "gene_name": "LOC100148897",
        "organism": "Zebrafish",
        "refseq_name": "LOW QUALITY PROTEIN: uncharacterized protein",
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        "protein_names_refseq": "LOW QUALITY PROTEIN: uncharacterized protein",
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        "protein_name": "Trypsin inhibitor ClTI-1-like",
        "gene_name": "LOC108192158",
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        "gene_names_refseq": "LOC108192158",
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        "protein_names_refseq": "trypsin inhibitor ClTI-1-like",
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        "length": 216,
        "protein_name": "Uncharacterized protein",
        "gene_name": "LOC141377471",
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        "gene_names_uniprotkb": "LOC141377471",
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        "protein_name": "SCAN box domain-containing protein",
        "gene_name": "LOC141377487",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Induces gene transcription inhibition., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Acts as a ligand of the ADGRL1 and ADGRL3 receptors that are expressed at the surface of adjacent cells. Promotes the formation of filopodia and enlarged growth cone in neuronal cells. Mediates axon guidance and homophilic and heterophilic cell-cell adhesion. May function as a cellular signal transducer., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "protein_name": "Phosphatase and actin regulator",
        "gene_name": "LOC137487611",
        "organism": "Zebrafish",
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        "protein_name": "alanine transaminase",
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        "organism": "Zebrafish",
        "refseq_name": "alanine aminotransferase 2 isoform X1",
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        "protein_names_refseq": "alanine aminotransferase 2 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "ec_number_list": "2.6.1.2",
        "go_molecular_function": "GO:0008483 transaminase activity",
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        "gene_names_uniprotkb": "LOC141377531",
        "gene_names_refseq": "LOC141377531",
        "protein_names_uniprotkb": "Reverse transcriptase domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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    {
        "uniprot_canonical_ac": "A0AC58H7Z7-1",
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        "mass": 48431.0,
        "length": 437,
        "protein_name": "Probable G-protein coupled receptor 101",
        "gene_name": "gpr101",
        "organism": "Zebrafish",
        "refseq_name": "probable G-protein coupled receptor 101",
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        "gene_names_uniprotkb": "gpr101",
        "gene_names_refseq": "gpr101",
        "protein_names_uniprotkb": "Probable G-protein coupled receptor 101",
        "protein_names_refseq": "probable G-protein coupled receptor 101",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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    {
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        "uniprot_id": "A0AC58H809_DANRE",
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        "length": 303,
        "protein_name": "NAD-dependent protein deacylase sirtuin-5, mitochondrial",
        "gene_name": "LOC100536119",
        "organism": "Zebrafish",
        "refseq_name": "NAD-dependent protein deacylase sirtuin-5, mitochondrial isoform X2",
        "refseq_ac": "XP_073778126",
        "gene_names_uniprotkb": "LOC100536119; SIRT5",
        "gene_names_refseq": "LOC100536119",
        "protein_names_uniprotkb": "NAD-dependent protein deacylase sirtuin-5, mitochondrial; 2.3.1.-; Regulatory protein SIR2 homolog 5; SIR2-like protein 5",
        "protein_names_refseq": "NAD-dependent protein deacylase sirtuin-5, mitochondrial isoform X2",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo., [UniProtKB, HAMAP, UniProtKB]",
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        "protein_name": "Coiled-coil domain-containing protein 160",
        "gene_name": "ccdc160",
        "organism": "Zebrafish",
        "refseq_name": "coiled-coil domain-containing protein 160",
        "refseq_ac": "XP_073778118",
        "gene_names_uniprotkb": "ccdc160",
        "gene_names_refseq": "ccdc160",
        "protein_names_uniprotkb": "Coiled-coil domain-containing protein 160",
        "protein_names_refseq": "coiled-coil domain-containing protein 160",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Phospholipid-transporting ATPase",
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        "protein_name": "Unconventional myosin-Ic",
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        "protein_names_uniprotkb": "A-type potassium channel modulatory protein KCNIP1 isoform X3",
        "protein_names_refseq": "A-type potassium channel modulatory protein KCNIP1 isoform X3",
        "tax_id": 7955,
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        "protein_name": "Mitofusin-1 isoform X1",
        "gene_name": "mfn1a",
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        "refseq_name": "mitofusin-1 isoform X1",
        "refseq_ac": "XP_073778770",
        "gene_names_uniprotkb": "mfn1a",
        "gene_names_refseq": "mfn1a",
        "protein_names_uniprotkb": "Mitofusin-1 isoform X1",
        "protein_names_refseq": "mitofusin-1 isoform X1",
        "tax_id": 7955,
        "disease": "Charcot-Marie-Tooth disease type 2 (Disease Ontology:DOID:0050539); Charcot-Marie-Tooth disease type 2A2A (Disease Ontology:DOID:0110155); Charcot-Marie-Tooth disease type 2A2B (Disease Ontology:DOID:0111557); Charcot-Marie-Tooth disease (Disease Ontology:DOID:10595); Alzheimer's disease (Disease Ontology:DOID:10652); adult respiratory distress syndrome (Disease Ontology:DOID:11394); dental fluorosis (Disease Ontology:DOID:13711); primary pulmonary hypertension (Disease Ontology:DOID:14557); status epilepticus (Disease Ontology:DOID:1824); acute kidney failure (Disease Ontology:DOID:3021); rhinitis (Disease Ontology:DOID:4483); migraine (Disease Ontology:DOID:6364); pulmonary hypertension (Disease Ontology:DOID:6432); chronic kidney disease (Disease Ontology:DOID:784)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding",
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        "protein_name": "Colorectal cancer associated 2 isoform X1",
        "gene_name": "linc.pou2af1; pou2af1",
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        "refseq_name": "colorectal cancer associated 2 isoform X1",
        "refseq_ac": "XP_073779287",
        "gene_names_uniprotkb": "linc.pou2af1; pou2af1; fb09h07; linc.pou2af1; si:ch211-213d14.2; wu:fb09h07",
        "gene_names_refseq": "fb09h07; linc.pou2af1; si:ch211-213d14.2; wu:fb09h07",
        "protein_names_uniprotkb": "Colorectal cancer associated 2 isoform X1",
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        "protein_name": "Leucine-rich repeat-containing protein 52 isoform X1",
        "gene_name": "LOC101882074",
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        "protein_names_refseq": "leucine-rich repeat-containing protein 52 isoform X1",
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        "ec_number_list": "3.1.3.2;3.1.3.48;3.1.3.1",
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
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        "record_id": "A0AC58H9U2-1",
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    },
    {
        "uniprot_canonical_ac": "A0AC58H9V3-1",
        "uniprot_id": "A0AC58H9V3_DANRE",
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        "length": 340,
        "protein_name": "Guanine nucleotide-binding protein subunit beta-4",
        "gene_name": "gnb4a",
        "organism": "Zebrafish",
        "refseq_name": "guanine nucleotide-binding protein subunit beta-4",
        "refseq_ac": "XP_073778764",
        "gene_names_uniprotkb": "gnb4a",
        "gene_names_refseq": "gnb4a",
        "protein_names_uniprotkb": "Guanine nucleotide-binding protein subunit beta-4",
        "protein_names_refseq": "guanine nucleotide-binding protein subunit beta-4",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction., [UniProtKB, UniProtKB]",
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        "missing_score": 10000,
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        "secondary_ac_list": "A0AC58H9X5",
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        "synthesized_glycan_count": 0,
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        "record_id": "A0AC58H9V3-1",
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    },
    {
        "uniprot_canonical_ac": "A0AC58HAA9-1",
        "uniprot_id": "A0AC58HAA9_DANRE",
        "mass": 44242.0,
        "length": 391,
        "protein_name": "P2X purinoceptor",
        "gene_name": "p2rx8",
        "organism": "Zebrafish",
        "refseq_name": "purinergic receptor P2X, ligand-gated ion channel, 8 isoform X1",
        "refseq_ac": "XP_073778908",
        "gene_names_uniprotkb": "p2rx8; P2X.514; p2xr514",
        "gene_names_refseq": "P2X.514; p2rx8; p2xr514",
        "protein_names_uniprotkb": "P2X purinoceptor",
        "protein_names_refseq": "purinergic receptor P2X, ligand-gated ion channel, 8 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Receptor for ATP that acts as a ligand-gated ion channel., [UniProtKB, UniProtKB, UniProtKB]",
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        "record_id": "A0AC58HAA9-1",
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        "length": 403,
        "protein_name": "Glia-derived nexin isoform X1",
        "gene_name": "serpine2",
        "organism": "Zebrafish",
        "refseq_name": "glia-derived nexin isoform X1",
        "refseq_ac": "XP_073778914",
        "gene_names_uniprotkb": "serpine2; zgc:55929",
        "gene_names_refseq": "serpine2; zgc:55929",
        "protein_names_uniprotkb": "Glia-derived nexin isoform X1",
        "protein_names_refseq": "glia-derived nexin isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "uniprot_canonical_ac": "A0AC58HAE6-1",
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        "length": 1238,
        "protein_name": "non-specific serine/threonine protein kinase",
        "gene_name": "sik3",
        "organism": "Zebrafish",
        "refseq_name": "serine/threonine-protein kinase SIK3 homolog isoform X1",
        "refseq_ac": "XP_073778929",
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        "gene_names_refseq": "sik3; zgc:66101; zgc:85904",
        "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1",
        "protein_names_refseq": "serine/threonine-protein kinase SIK3 homolog isoform X1",
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        "predicted_glycosites": 3,
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        "ec_number_list": "2.7.11.1;2.7.11.13;2.7.11.25;2.7.10.1;2.7.11.22;2.7.11.21;2.7.11.17;2.7.12.1;2.7.12.2;2.7.11.24;2.7.10.2;2.7.11.23;2.7.1.150;2.7.11.12;2.7.11.39;2.7.11.11;2.7.1.153;2.7.1.137;2.7.1.154;2.7.11.26;2.7.11.31",
        "go_molecular_function": "GO:0016301 kinase activity",
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        "record_id": "A0AC58HAE6-1",
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    {
        "uniprot_canonical_ac": "A0AC58HAI0-1",
        "uniprot_id": "A0AC58HAI0_DANRE",
        "mass": 60602.0,
        "length": 536,
        "protein_name": "Serine--tRNA ligase, mitochondrial",
        "gene_name": "sars2",
        "organism": "Zebrafish",
        "refseq_name": "serine--tRNA ligase, mitochondrial isoform X1",
        "refseq_ac": "XP_073778986",
        "gene_names_uniprotkb": "sars2; SerRS2; zgc:66345",
        "gene_names_refseq": "SerRS2; sars2; zgc:66345",
        "protein_names_uniprotkb": "Serine--tRNA ligase, mitochondrial; 6.1.1.11; SerRSmt; Seryl-tRNA synthetase; Seryl-tRNA(Ser/Sec) synthetase",
        "protein_names_refseq": "serine--tRNA ligase, mitochondrial isoform X1",
        "tax_id": 7955,
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    {
        "uniprot_canonical_ac": "A0AC58HAJ2-1",
        "uniprot_id": "A0AC58HAJ2_DANRE",
        "mass": 25989.0,
        "length": 238,
        "protein_name": "Myelin protein zero-like protein 3 isoform X1",
        "gene_name": "mpzl3",
        "organism": "Zebrafish",
        "refseq_name": "myelin protein zero-like protein 3 precursor",
        "refseq_ac": "NP_998334",
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        "gene_names_refseq": "hm:zeh0677; mpzl3; wu:fi33f03; zgc:85923",
        "protein_names_uniprotkb": "Myelin protein zero-like protein 3 isoform X1",
        "protein_names_refseq": "myelin protein zero-like protein 3 precursor",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01026819.1, SRR32588733.840189.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On or before Jul 8, 2025 this sequence version replaced XP_073779009.1, NP_998334.1., [RefSeq]",
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        "ec_number_list": "",
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HB12-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HB33-1",
        "uniprot_id": "A0AC58HB33_DANRE",
        "mass": 52724.0,
        "length": 476,
        "protein_name": "Heat shock 70 kDa protein 13",
        "gene_name": "hspa13",
        "organism": "Zebrafish",
        "refseq_name": "heat shock 70 kDa protein 13 isoform X1",
        "refseq_ac": "XP_073779198",
        "gene_names_uniprotkb": "hspa13; stch; zgc:162281",
        "gene_names_refseq": "hspa13; stch; zgc:162281",
        "protein_names_uniprotkb": "Heat shock 70 kDa protein 13; Stress-70 protein chaperone microsome-associated 60 kDa protein",
        "protein_names_refseq": "heat shock 70 kDa protein 13 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Has peptide-independent ATPase activity., [UniProtKB, UniProtKB, UniProtKB]",
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        "missing_score": 10000,
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        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HB33-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HEV2-1",
        "uniprot_id": "A0AC58HEV2_DANRE",
        "mass": 14559.0,
        "length": 132,
        "protein_name": "TYRO protein tyrosine kinase-binding protein",
        "gene_name": "tyrobp",
        "organism": "Zebrafish",
        "refseq_name": "TYRO protein tyrosine kinase-binding protein isoform X2",
        "refseq_ac": "XP_073780525",
        "gene_names_uniprotkb": "tyrobp; dap12; tyrpbp",
        "gene_names_refseq": "dap12; tyrobp; tyrpbp",
        "protein_names_uniprotkb": "TYRO protein tyrosine kinase-binding protein; DNAX-activation protein 12",
        "protein_names_refseq": "TYRO protein tyrosine kinase-binding protein isoform X2",
        "tax_id": 7955,
        "disease": "Nasu-Hakola disease (Disease Ontology:DOID:0090112); rheumatoid arthritis (Disease Ontology:DOID:7148)",
        "pathway": " (dre:100101461)",
        "pathway_count": 1,
        "publication_count": 2,
        "publication_id_list": "17719728;17891481",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0046872 metal ion binding;GO:0016301 kinase activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface",
        "go_biological_process": "GO:0030316 osteoclast differentiation;GO:0002283 neutrophil activation involved in immune response;GO:1904151 positive regulation of microglial cell mediated cytotoxicity;GO:0007166 cell surface receptor signaling pathway;GO:0034241 positive regulation of macrophage fusion",
        "synthesized_glycan_count": 0,
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        "record_type": "protein"
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        "uniprot_id": "A0AC58HD37_DANRE",
        "mass": 322727.0,
        "length": 2899,
        "protein_name": "Neurobeachin",
        "gene_name": "nbeab",
        "organism": "Zebrafish",
        "refseq_name": "neurobeachin isoform X1",
        "refseq_ac": "XP_073779907",
        "gene_names_uniprotkb": "nbeab",
        "gene_names_refseq": "nbeab",
        "protein_names_uniprotkb": "Neurobeachin; Lysosomal-trafficking regulator 2",
        "protein_names_refseq": "neurobeachin isoform X1",
        "tax_id": 7955,
        "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041); stomach cancer (Disease Ontology:DOID:10534)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 2,
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        "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane",
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        "length": 1040,
        "protein_name": "Cilia- and flagella-associated protein 337 isoform X1",
        "gene_name": "wdr95",
        "organism": "Zebrafish",
        "refseq_name": "cilia- and flagella-associated protein 337 isoform X1",
        "refseq_ac": "XP_073779939",
        "gene_names_uniprotkb": "wdr95",
        "gene_names_refseq": "wdr95",
        "protein_names_uniprotkb": "Cilia- and flagella-associated protein 337 isoform X1",
        "protein_names_refseq": "cilia- and flagella-associated protein 337 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "GO:0005509 calcium ion binding",
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        "uniprot_id": "A0AC58HCT5_DANRE",
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        "length": 506,
        "protein_name": "Na(+)/H(+) exchange regulatory cofactor NHE-RF4 isoform X2",
        "gene_name": "nherf4a",
        "organism": "Zebrafish",
        "refseq_name": "Na(+)/H(+) exchange regulatory cofactor NHE-RF4 isoform X2",
        "refseq_ac": "XP_073779792",
        "gene_names_uniprotkb": "nherf4a",
        "gene_names_refseq": "nherf4a",
        "protein_names_uniprotkb": "Na(+)/H(+) exchange regulatory cofactor NHE-RF4 isoform X2",
        "protein_names_refseq": "Na(+)/H(+) exchange regulatory cofactor NHE-RF4 isoform X2",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0043495 protein-membrane adaptor activity",
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        "protein_name": "small monomeric GTPase",
        "gene_name": "zgc:171704",
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        "refseq_ac": "XP_073780526",
        "gene_names_uniprotkb": "zgc:171704; zgc:171704",
        "gene_names_refseq": "zgc:171704",
        "protein_names_uniprotkb": "small monomeric GTPase; 3.6.5.2",
        "protein_names_refseq": "ras-related and estrogen-regulated growth inhibitor-like protein isoform X1",
        "tax_id": 7955,
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        "pathway": " (dre:100124619)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0AC58HEW3;A0AC58HEW4;A0AC58HEX3;A0AC58HEX6;A0AC58HEY4;A0AC58HF01",
        "ec_number_list": "3.6.5.2;3.6.5.3;3.6.5.5;3.6.1.5;3.6.5.-;3.6.1.-;3.6.5.4",
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    },
    {
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        "uniprot_id": "A0AC58HE66_DANRE",
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        "protein_name": "Kelch repeat and BTB domain-containing protein 3 isoform X1",
        "gene_name": "kbtbd3",
        "organism": "Zebrafish",
        "refseq_name": "kelch repeat and BTB domain-containing protein 3 isoform X1",
        "refseq_ac": "XP_073780249",
        "gene_names_uniprotkb": "kbtbd3",
        "gene_names_refseq": "kbtbd3",
        "protein_names_uniprotkb": "Kelch repeat and BTB domain-containing protein 3 isoform X1",
        "protein_names_refseq": "kelch repeat and BTB domain-containing protein 3 isoform X1",
        "tax_id": 7955,
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        "pathway": " (dre:100003277)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "protein_name": "Sialate:O-sulfotransferase 1",
        "gene_name": "wscd1a",
        "organism": "Zebrafish",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01016584.1, SRR32588729.37603446.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505372, SAMEA3505373 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Jun 12, 2025 this sequence version replaced XP_073779897.1., [RefSeq]",
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        "record_id": "A0AC58HDU1-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HDY3-1",
        "uniprot_id": "A0AC58HDY3_DANRE",
        "mass": 82098.0,
        "length": 738,
        "protein_name": "guanylate cyclase",
        "gene_name": "gucy1a2",
        "organism": "Zebrafish",
        "refseq_name": "guanylate cyclase soluble subunit alpha-2 isoform X1",
        "refseq_ac": "XP_073780175",
        "gene_names_uniprotkb": "gucy1a2",
        "gene_names_refseq": "gucy1a2",
        "protein_names_uniprotkb": "guanylate cyclase; 4.6.1.2",
        "protein_names_refseq": "guanylate cyclase soluble subunit alpha-2 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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    {
        "uniprot_canonical_ac": "A0AC58HDW2-1",
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        "length": 565,
        "protein_name": "NADPH oxidase 4",
        "gene_name": "nox4",
        "organism": "Zebrafish",
        "refseq_name": "NADPH oxidase 4 isoform X1",
        "refseq_ac": "XP_073780177",
        "gene_names_uniprotkb": "nox4",
        "gene_names_refseq": "nox4",
        "protein_names_uniprotkb": "NADPH oxidase 4; 1.6.3.1",
        "protein_names_refseq": "NADPH oxidase 4 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; NADPH oxidase that catalyzes predominantly the reduction of oxygen to H2O2. Can also catalyze to a smaller extent, the reduction of oxygen to superoxide. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation. Promotes ferroptosis, reactive oxygen species production and reduced glutathione (GSH) levels by activating NLRP3 inflammasome activation and cytokine release., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "ec_number_list": "1.6.3.1;1.14.13.225;1.-.-.-;1.6.99.1",
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        "gene_name": "LOC141377923",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": "XP_073780188",
        "gene_names_uniprotkb": "LOC141377923",
        "gene_names_refseq": "LOC141377923",
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        "protein_names_refseq": "uncharacterized protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]",
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        "record_id": "A0AC58HDX0-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58HDX5-1",
        "uniprot_id": "A0AC58HDX5_DANRE",
        "mass": 36027.0,
        "length": 309,
        "protein_name": "C2H2-type domain-containing protein",
        "gene_name": "LOC101883356",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized LOC101883356",
        "refseq_ac": "NP_001429543",
        "gene_names_uniprotkb": "LOC101883356",
        "gene_names_refseq": "LOC101883356",
        "protein_names_uniprotkb": "C2H2-type domain-containing protein",
        "protein_names_refseq": "uncharacterized LOC101883356",
        "tax_id": 7955,
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588722.28180924.1, SRR32588725.46616129.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN18715719, SAMN18715720 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Aug 15, 2025 this sequence version replaced XP_073780193.1., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]",
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "A0AC58HDY5",
        "ec_number_list": "",
        "go_molecular_function": "",
        "go_cellular_component": "",
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        "synthesized_glycan_count": 0,
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        "record_id": "A0AC58HDX5-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58HDY2-1",
        "uniprot_id": "A0AC58HDY2_DANRE",
        "mass": 23758.0,
        "length": 211,
        "protein_name": "Ras-related protein Rab",
        "gene_name": "rab38a",
        "organism": "Zebrafish",
        "refseq_name": "ras-related protein Rab-38",
        "refseq_ac": "XP_073780197",
        "gene_names_uniprotkb": "rab38a",
        "gene_names_refseq": "rab38a",
        "protein_names_uniprotkb": "Ras-related protein Rab",
        "protein_names_refseq": "ras-related protein Rab-38",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; The small GTPases Rab are key regulators in vesicle trafficking., [UniProtKB, UniProtKB]",
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        "missing_score": 10000,
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        "record_id": "A0AC58HDY2-1",
        "record_type": "protein"
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    {
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        "length": 413,
        "protein_name": "Myb/SANT-like DNA-binding domain-containing protein 4",
        "gene_name": "msantd4",
        "organism": "Zebrafish",
        "refseq_name": "myb/SANT-like DNA-binding domain-containing protein 4",
        "refseq_ac": "XP_073780201",
        "gene_names_uniprotkb": "msantd4",
        "gene_names_refseq": "msantd4",
        "protein_names_uniprotkb": "Myb/SANT-like DNA-binding domain-containing protein 4",
        "protein_names_refseq": "myb/SANT-like DNA-binding domain-containing protein 4",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "missing_score": 10000,
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        "secondary_ac_list": "A0AC58HDZ2;A0AC58HE25",
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        "synthesized_glycan_count": 0,
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        "record_id": "A0AC58HDY8-1",
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    {
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        "mass": 77855.0,
        "length": 679,
        "protein_name": "Interleukin-1 receptor accessory protein isoform X1",
        "gene_name": "il1rap",
        "organism": "Zebrafish",
        "refseq_name": "interleukin-1 receptor accessory protein isoform X1",
        "refseq_ac": "XP_073780208",
        "gene_names_uniprotkb": "il1rap",
        "gene_names_refseq": "il1rap",
        "protein_names_uniprotkb": "Interleukin-1 receptor accessory protein isoform X1",
        "protein_names_refseq": "interleukin-1 receptor accessory protein isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "refseq_name": "presenilin-associated rhomboid-like protein, mitochondrial isoform X1",
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        "gene_name": "LOC101886389",
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        "protein_name": "Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 isoform X1",
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        "organism": "Zebrafish",
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        "refseq_ac": "NP_001429982",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01020784.1, SRR32588733.2256712.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from JBMGRA010000015.1. On Sep 4, 2025 this sequence version replaced XP_073780231.1., [RefSeq]",
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        "length": 944,
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        "gene_name": "LOC137487689",
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        "protein_name": "Centrosomal protein of 164 kDa",
        "gene_name": "cep164",
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        "protein_name": "Uncharacterized protein",
        "gene_name": "LOC100002043",
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        "refseq_name": "uncharacterized protein LOC100002043",
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        "gene_names_uniprotkb": "LOC100002043",
        "gene_names_refseq": "LOC100002043",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "uncharacterized protein LOC100002043",
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    },
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        "length": 877,
        "protein_name": "Mitogen-activated protein kinase kinase kinase kinase",
        "gene_name": "map4k1",
        "organism": "Zebrafish",
        "refseq_name": "mitogen-activated protein kinase kinase kinase kinase 5 isoform X1",
        "refseq_ac": "XP_073780260",
        "gene_names_uniprotkb": "map4k1",
        "gene_names_refseq": "map4k1",
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        "protein_names_refseq": "mitogen-activated protein kinase kinase kinase kinase 5 isoform X1",
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        "ec_number_list": "2.7.11.1;2.7.11.13;2.7.11.25;2.7.10.1;2.7.11.22;2.7.11.21;2.7.11.17;2.7.12.1;2.7.12.2;2.7.11.24;2.7.10.2;2.7.11.23;2.7.1.150;2.7.11.12;2.7.11.39;2.7.11.11;2.7.1.153;2.7.1.137;2.7.1.154;2.7.11.26;2.7.11.31",
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        "length": 394,
        "protein_name": "Transmembrane protein 25 isoform X2",
        "gene_name": "tmem25",
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        "refseq_name": "transmembrane protein 25 isoform X2",
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        "gene_names_uniprotkb": "tmem25",
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        "gene_names_refseq": "LOC141377947",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
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        "protein_name": "Myelin protein zero-like protein 2",
        "gene_name": "LOC141377950",
        "organism": "Zebrafish",
        "refseq_name": "myelin protein zero-like protein 2",
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        "organism": "Zebrafish",
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        "gene_names_uniprotkb": "LOC137487800",
        "gene_names_refseq": "LOC137487800",
        "protein_names_uniprotkb": "C2H2-type domain-containing protein",
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        "gene_name": "LOC141377977",
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        "length": 1373,
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        "gene_name": "cep295",
        "organism": "Zebrafish",
        "refseq_name": "centrosomal protein 295",
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        "gene_names_uniprotkb": "cep295",
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        "protein_names_refseq": "centrosomal protein 295",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588722.12582884.1, SRR32588734.3521071.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Aug 7, 2025 this sequence version replaced XP_073780324.1., [RefSeq]",
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        "gene_name": "LOC141377967",
        "organism": "Zebrafish",
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        "length": 305,
        "protein_name": "Odorant receptor 128-7",
        "gene_name": "or64g1",
        "organism": "Zebrafish",
        "refseq_name": "odorant receptor 128-7",
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        "protein_name": "Fibronectin type-III domain-containing protein 3A",
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        "protein_name": "Uncharacterized protein",
        "gene_name": "LOC141377975",
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        "refseq_ac": "XP_073780395",
        "gene_names_uniprotkb": "si:dkey-77f5.4",
        "gene_names_refseq": "si:dkey-77f5.4",
        "protein_names_uniprotkb": "Uncharacterized protein si:dkey-77f5.4",
        "protein_names_refseq": "uncharacterized protein si:dkey-77f5.4",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]",
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        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HEI9-1",
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        "mass": 48530.0,
        "length": 424,
        "protein_name": "Uncharacterized protein si:ch73-144d13.4",
        "gene_name": "si:ch73-144d13.4",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:ch73-144d13.4",
        "refseq_ac": "XP_073780397",
        "gene_names_uniprotkb": "si:ch73-144d13.4",
        "gene_names_refseq": "si:ch73-144d13.4",
        "protein_names_uniprotkb": "Uncharacterized protein si:ch73-144d13.4",
        "protein_names_refseq": "uncharacterized protein si:ch73-144d13.4",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "length": 200,
        "protein_name": "LHFPL tetraspan subfamily member 6 protein isoform X1",
        "gene_name": "LOC100334706",
        "organism": "Zebrafish",
        "refseq_name": "LHFPL tetraspan subfamily member 6 protein isoform X1",
        "refseq_ac": "XP_073780417",
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        "gene_names_refseq": "LOC100334706",
        "protein_names_uniprotkb": "LHFPL tetraspan subfamily member 6 protein isoform X1",
        "protein_names_refseq": "LHFPL tetraspan subfamily member 6 protein isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "missing_score": 10000,
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        "record_type": "protein"
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        "uniprot_id": "A0AC58HEJ2_DANRE",
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        "length": 412,
        "protein_name": "Uncharacterized protein si:dkey-7i4.24 isoform X1",
        "gene_name": "si:dkey-7i4.24",
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        "refseq_name": "uncharacterized protein si:dkey-7i4.24 isoform X1",
        "refseq_ac": "XP_073780398",
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        "gene_names_refseq": "si:dkey-7i4.24",
        "protein_names_uniprotkb": "Uncharacterized protein si:dkey-7i4.24 isoform X1",
        "protein_names_refseq": "uncharacterized protein si:dkey-7i4.24 isoform X1",
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        "secondary_ac_list": "A0AC58HEM5",
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        "length": 242,
        "protein_name": "TPA-induced transmembrane protein",
        "gene_name": "c15h3orf52",
        "organism": "Zebrafish",
        "refseq_name": "TPA-induced transmembrane protein",
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        "gene_names_refseq": "c15h3orf52",
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        "protein_names_refseq": "TPA-induced transmembrane protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58HEJ9-1",
        "uniprot_id": "A0AC58HEJ9_DANRE",
        "mass": 23236.0,
        "length": 215,
        "protein_name": "Claudin",
        "gene_name": "LOC100333863",
        "organism": "Zebrafish",
        "refseq_name": "claudin-3-like",
        "refseq_ac": "NP_001429823",
        "gene_names_uniprotkb": "LOC100333863",
        "gene_names_refseq": "LOC100333863",
        "protein_names_uniprotkb": "Claudin",
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        "function": "##Evidence-Data-START## Transcript is intronless :: SRR32588723.3786949.1, SRR32588722.1962049.1 [ECO:0000345] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1., [RefSeq]; Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia., [UniProtKB, UniProtKB]",
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    {
        "uniprot_canonical_ac": "A0AC58HEK3-1",
        "uniprot_id": "A0AC58HEK3_DANRE",
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        "length": 908,
        "protein_name": "Reverse transcriptase domain-containing protein",
        "gene_name": "LOC141377999",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
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        "gene_names_uniprotkb": "LOC141377999",
        "gene_names_refseq": "LOC141377999",
        "protein_names_uniprotkb": "Reverse transcriptase domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "record_id": "A0AC58HEK3-1",
        "record_type": "protein"
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        "uniprot_canonical_ac": "A0AC58HEK7-1",
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        "length": 290,
        "protein_name": "C2H2-type domain-containing protein",
        "gene_name": "LOC110437883",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
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        "organism": "Zebrafish",
        "refseq_name": "TRPM8 channel-associated factor homolog",
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        "gene_names_refseq": "si:ch211-210b2.4",
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        "protein_names_refseq": "TRPM8 channel-associated factor homolog",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "record_id": "A0AC58HEK9-1",
        "record_type": "protein"
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        "uniprot_canonical_ac": "A0AC58HEL1-1",
        "uniprot_id": "A0AC58HEL1_DANRE",
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        "length": 186,
        "protein_name": "V-set and transmembrane domain-containing protein 5",
        "gene_name": "vstm5",
        "organism": "Zebrafish",
        "refseq_name": "V-set and transmembrane domain-containing protein 5",
        "refseq_ac": "XP_073780421",
        "gene_names_uniprotkb": "vstm5",
        "gene_names_refseq": "vstm5",
        "protein_names_uniprotkb": "V-set and transmembrane domain-containing protein 5",
        "protein_names_refseq": "V-set and transmembrane domain-containing protein 5",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "record_id": "A0AC58HEL1-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58HEL4-1",
        "uniprot_id": "A0AC58HEL4_DANRE",
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        "length": 461,
        "protein_name": "Serine/threonine-protein kinase Nek3 isoform X1",
        "gene_name": "nek3",
        "organism": "Zebrafish",
        "refseq_name": "serine/threonine-protein kinase Nek3 isoform X1",
        "refseq_ac": "XP_073780424",
        "gene_names_uniprotkb": "nek3",
        "gene_names_refseq": "nek3",
        "protein_names_uniprotkb": "Serine/threonine-protein kinase Nek3 isoform X1",
        "protein_names_refseq": "serine/threonine-protein kinase Nek3 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "secondary_ac_list": "",
        "ec_number_list": "2.7.11.1;2.7.11.13;2.7.11.25;2.7.10.1;2.7.11.22;2.7.11.21;2.7.11.17;2.7.12.1;2.7.12.2;2.7.11.24;2.7.10.2;2.7.11.23;2.7.1.150;2.7.11.12;2.7.11.39;2.7.11.11;2.7.1.153;2.7.1.137;2.7.1.154;2.7.11.26;2.7.11.31",
        "go_molecular_function": "GO:0016301 kinase activity",
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    {
        "uniprot_canonical_ac": "A0AC58HEP7-1",
        "uniprot_id": "A0AC58HEP7_DANRE",
        "mass": 57272.0,
        "length": 503,
        "protein_name": "Ubiquitin carboxyl-terminal hydrolase MINDY",
        "gene_name": "mindy4b",
        "organism": "Zebrafish",
        "refseq_name": "inactive ubiquitin carboxyl-terminal hydrolase MINDY-4B isoform X9",
        "refseq_ac": "XP_073780455",
        "gene_names_uniprotkb": "mindy4b",
        "gene_names_refseq": "mindy4b",
        "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase MINDY; 3.4.19.12",
        "protein_names_refseq": "inactive ubiquitin carboxyl-terminal hydrolase MINDY-4B isoform X9",
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        "go_molecular_function": "GO:0016787 hydrolase activity",
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        "length": 460,
        "protein_name": "CCHC-type domain-containing protein",
        "gene_name": "LOC141377982",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
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        "gene_names_uniprotkb": "LOC141377982",
        "gene_names_refseq": "LOC141377982",
        "protein_names_uniprotkb": "CCHC-type domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "hit_score": 0.1,
        "record_id": "A0AC58HEN0-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HEN1-1",
        "uniprot_id": "A0AC58HEN1_DANRE",
        "mass": 66147.0,
        "length": 590,
        "protein_name": "Protein Atg16l2",
        "gene_name": "atg16l2",
        "organism": "Zebrafish",
        "refseq_name": "ATG16 autophagy related 16-like 2",
        "refseq_ac": "NP_001428389",
        "gene_names_uniprotkb": "atg16l2",
        "gene_names_refseq": "atg16l2; si:ch211-152c12.1",
        "protein_names_uniprotkb": "Protein Atg16l2; APG16-like 2; Autophagy-related protein 16-2",
        "protein_names_refseq": "ATG16 autophagy related 16-like 2; protein Atg16l2",
        "tax_id": 7955,
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        "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01011462.1, GFIL01020797.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505375 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Jun 11, 2025 this sequence version replaced XP_073780440.1., [RefSeq]; May play a role in regulating epithelial homeostasis in an ATG16L1-dependent manner., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "missing_score": 10000,
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        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58HEN8-1",
        "uniprot_id": "A0AC58HEN8_DANRE",
        "mass": 159586.0,
        "length": 1425,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC110437863",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073780443",
        "gene_names_uniprotkb": "LOC110437863",
        "gene_names_refseq": "LOC110437863",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HEN8-1",
        "record_type": "protein"
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        "uniprot_canonical_ac": "A0AC58HEP3-1",
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        "mass": 46607.0,
        "length": 409,
        "protein_name": "E3 ubiquitin-protein ligase RNF14",
        "gene_name": "LOC110437942",
        "organism": "Zebrafish",
        "refseq_name": "E3 ubiquitin-protein ligase RNF14-like",
        "refseq_ac": "XP_073780462",
        "gene_names_uniprotkb": "LOC110437942",
        "gene_names_refseq": "LOC110437942",
        "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RNF14; 2.3.2.31; RING finger protein 14",
        "protein_names_refseq": "E3 ubiquitin-protein ligase RNF14-like",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HEP3-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58HEQ2-1",
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        "mass": 72550.0,
        "length": 607,
        "protein_name": "C2H2-type domain-containing protein",
        "gene_name": "LOC141378017",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": "XP_073780480",
        "gene_names_uniprotkb": "LOC141378017",
        "gene_names_refseq": "LOC141378017",
        "protein_names_uniprotkb": "C2H2-type domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio                   :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]",
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        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HEQ2-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58HEQ5-1",
        "uniprot_id": "A0AC58HEQ5_DANRE",
        "mass": 55470.0,
        "length": 492,
        "protein_name": "Thymus-specific serine protease",
        "gene_name": "prss16",
        "organism": "Zebrafish",
        "refseq_name": "thymus-specific serine protease",
        "refseq_ac": "XP_073780478",
        "gene_names_uniprotkb": "prss16",
        "gene_names_refseq": "prss16",
        "protein_names_uniprotkb": "Thymus-specific serine protease",
        "protein_names_refseq": "thymus-specific serine protease",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "GO:0008233 peptidase activity",
        "go_cellular_component": "",
        "go_biological_process": "GO:0006508 proteolysis",
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        "record_id": "A0AC58HEQ5-1",
        "record_type": "protein"
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        "length": 763,
        "protein_name": "Ras and Rab interactor-like protein isoform X1",
        "gene_name": "rinl",
        "organism": "Zebrafish",
        "refseq_name": "ras and Rab interactor-like protein isoform X1",
        "refseq_ac": "XP_073780474",
        "gene_names_uniprotkb": "rinl",
        "gene_names_refseq": "rinl",
        "protein_names_uniprotkb": "Ras and Rab interactor-like protein isoform X1",
        "protein_names_refseq": "ras and Rab interactor-like protein isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "A0AC58HEV4",
        "ec_number_list": "",
        "go_molecular_function": "",
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        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58HEQ9-1",
        "uniprot_id": "A0AC58HEQ9_DANRE",
        "mass": 37230.0,
        "length": 327,
        "protein_name": "Probable G-protein coupled receptor 34",
        "gene_name": "LOC141378002",
        "organism": "Zebrafish",
        "refseq_name": "G-protein coupled receptor 87-like",
        "refseq_ac": "XP_073780469",
        "gene_names_uniprotkb": "LOC141378002",
        "gene_names_refseq": "LOC141378002",
        "protein_names_uniprotkb": "Probable G-protein coupled receptor 34",
        "protein_names_refseq": "G-protein coupled receptor 87-like",
        "tax_id": 7955,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; G-protein-coupled receptor of lysophosphatidylserine (LysoPS) that plays different roles in immune response. Acts a damage-sensing receptor that triggers tissue repair upon recognition of dying neutrophils. Mechanistically, apoptotic neutrophils release lysophosphatydilserine that are recognized by type 3 innate lymphoid cells (ILC3s) via GPR34, which activates downstream PI3K-AKT and RAS-ERK signaling pathways leading to STAT3 activation and IL-22 production. Plays an important role in microglial function, controlling morphology and phagocytosis., [UniProtKB, UniProtKB]",
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        "missing_score": 10000,
        "biomarker_type": "",
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        "protein_name": "non-specific serine/threonine protein kinase",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "ec_number_list": "2.7.11.1;2.7.11.13;2.7.11.25;2.7.10.1;2.7.11.22;2.7.11.21;2.7.11.17;2.7.12.1;2.7.12.2;2.7.11.24;2.7.10.2;2.7.11.23;2.7.1.150;2.7.11.12;2.7.11.39;2.7.11.11;2.7.1.153;2.7.1.137;2.7.1.154;2.7.11.26;2.7.11.31",
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        "protein_name": "Probable G-protein coupled receptor 34",
        "gene_name": "LOC141378003",
        "organism": "Zebrafish",
        "refseq_name": "P2Y purinoceptor 14-like",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; G-protein-coupled receptor of lysophosphatidylserine (LysoPS) that plays different roles in immune response. Acts a damage-sensing receptor that triggers tissue repair upon recognition of dying neutrophils. Mechanistically, apoptotic neutrophils release lysophosphatydilserine that are recognized by type 3 innate lymphoid cells (ILC3s) via GPR34, which activates downstream PI3K-AKT and RAS-ERK signaling pathways leading to STAT3 activation and IL-22 production. Plays an important role in microglial function, controlling morphology and phagocytosis., [UniProtKB, UniProtKB]",
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        "protein_name": "LOW QUALITY PROTEIN: uncharacterized protein",
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        "protein_name": "Uncharacterized protein isoform X1",
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        "refseq_ac": "XP_073780499",
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        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
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        "protein_name": "Probable G-protein coupled receptor 34",
        "gene_name": "LOC141378004",
        "organism": "Zebrafish",
        "refseq_name": "P2Y purinoceptor 14-like",
        "refseq_ac": "XP_073780471",
        "gene_names_uniprotkb": "LOC141378004",
        "gene_names_refseq": "LOC141378004",
        "protein_names_uniprotkb": "Probable G-protein coupled receptor 34",
        "protein_names_refseq": "P2Y purinoceptor 14-like",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; G-protein-coupled receptor of lysophosphatidylserine (LysoPS) that plays different roles in immune response. Acts a damage-sensing receptor that triggers tissue repair upon recognition of dying neutrophils. Mechanistically, apoptotic neutrophils release lysophosphatydilserine that are recognized by type 3 innate lymphoid cells (ILC3s) via GPR34, which activates downstream PI3K-AKT and RAS-ERK signaling pathways leading to STAT3 activation and IL-22 production. Plays an important role in microglial function, controlling morphology and phagocytosis., [UniProtKB, UniProtKB]",
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        "protein_name": "V-set and Ig domain-containing protein isoform X2",
        "gene_name": "si:dkey-11p23.7",
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        "refseq_name": "V-set and Ig domain-containing protein isoform X2",
        "refseq_ac": "XP_073780500",
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        "gene_names_refseq": "si:dkey-11p23.7",
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        "protein_names_refseq": "V-set and Ig domain-containing protein isoform X2",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "length": 860,
        "protein_name": "Rap guanine nucleotide exchange factor 5b isoform X1",
        "gene_name": "rapgef5b",
        "organism": "Zebrafish",
        "refseq_name": "rap guanine nucleotide exchange factor 5b isoform 2",
        "refseq_ac": "NP_001429536",
        "gene_names_uniprotkb": "rapgef5b; rapgef5; si:dkey-233k19.1; zgc:165655",
        "gene_names_refseq": "rapgef5b; rapgef5; si:dkey-233k19.1; zgc:165655",
        "protein_names_uniprotkb": "Rap guanine nucleotide exchange factor 5b isoform X1",
        "protein_names_refseq": "rap guanine nucleotide exchange factor 5b isoform 2",
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        "function": "##Evidence-Data-START## Transcript exon combination :: GFIL01016590.1, GDQH01014903.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN06350654, SAMN06350655 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1. On Aug 15, 2025 this sequence version replaced XP_073780523.1., [RefSeq]",
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        "protein_name": "APC membrane recruitment protein 3",
        "gene_name": "amer3",
        "organism": "Zebrafish",
        "refseq_name": "APC membrane recruitment protein 3",
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        "gene_names_uniprotkb": "amer3",
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        "protein_names_uniprotkb": "APC membrane recruitment protein 3",
        "protein_names_refseq": "APC membrane recruitment protein 3",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "uniprot_id": "A0AC58HF58_DANRE",
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        "length": 1231,
        "protein_name": "Focal adhesion kinase 1",
        "gene_name": "ptk2ab",
        "organism": "Zebrafish",
        "refseq_name": "focal adhesion kinase 1 isoform X1",
        "refseq_ac": "XP_073780623",
        "gene_names_uniprotkb": "ptk2ab; fak1a; fak; ptk2.1; ptk2a; ptk2; wu:fa18c04; zgc:66114",
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        "protein_names_uniprotkb": "Focal adhesion kinase 1; 2.7.10.2; Protein-tyrosine kinase 2; pp125FAK",
        "protein_names_refseq": "focal adhesion kinase 1 isoform X1",
        "tax_id": 7955,
        "disease": "ductal carcinoma in situ (Disease Ontology:DOID:0060074); endometrial hyperplasia (Disease Ontology:DOID:0080365); prostate cancer (Disease Ontology:DOID:10283); hypertension (Disease Ontology:DOID:10763); nephritis (Disease Ontology:DOID:10952); leiomyoma (Disease Ontology:DOID:127); endometrial carcinoma (Disease Ontology:DOID:2871); endometriosis (Disease Ontology:DOID:289); cervix carcinoma (Disease Ontology:DOID:2893); ischemia (Disease Ontology:DOID:326); lung squamous cell carcinoma (Disease Ontology:DOID:3907); ovarian carcinoma (Disease Ontology:DOID:4001); cervical cancer (Disease Ontology:DOID:4362); uremia (Disease Ontology:DOID:4676); lung small cell carcinoma (Disease Ontology:DOID:5409); pulmonary hypertension (Disease Ontology:DOID:6432); hepatocellular carcinoma (Disease Ontology:DOID:684)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "ec_number_list": "2.7.10.1;2.7.10.2;2.7.11.1;2.7.12.1;2.7.12.2",
        "go_molecular_function": "GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0004713 protein tyrosine kinase activity;GO:0016301 kinase activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0005925 focal adhesion;GO:0005737 cytoplasm;GO:0042995 cell projection",
        "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0030154 cell differentiation;GO:0007172 signal complex assembly;GO:0021555 midbrain-hindbrain boundary morphogenesis;GO:0032880 regulation of protein localization",
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        "protein_name": "Kinesin-like protein KIF13A isoform X1",
        "gene_name": "kif13a",
        "organism": "Zebrafish",
        "refseq_name": "kinesin-like protein KIF13A isoform X1",
        "refseq_ac": "XP_073781621",
        "gene_names_uniprotkb": "kif13a",
        "gene_names_refseq": "kif13a",
        "protein_names_uniprotkb": "Kinesin-like protein KIF13A isoform X1",
        "protein_names_refseq": "kinesin-like protein KIF13A isoform X1",
        "tax_id": 7955,
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        "pathway": " (dre:100331282)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "reported_snv": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0003777 microtubule motor activity",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule",
        "go_biological_process": "GO:0048731 system development;GO:0045184 establishment of protein localization;GO:0007018 microtubule-based movement",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HHV3-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HGM6-1",
        "uniprot_id": "A0AC58HGM6_DANRE",
        "mass": 122518.0,
        "length": 1105,
        "protein_name": "Sema domain, transmembrane domain (TM), and cytoplasmic domain, (Semaphorin) 6C isoform X1",
        "gene_name": "sema6cb",
        "organism": "Zebrafish",
        "refseq_name": "sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C isoform X1",
        "refseq_ac": "XP_073781138",
        "gene_names_uniprotkb": "sema6cb; bZ1N7.1; sema6e; si:rp71-1n7.1",
        "gene_names_refseq": "bZ1N7.1; sema6cb; sema6e; si:rp71-1n7.1",
        "protein_names_uniprotkb": "Sema domain, transmembrane domain (TM), and cytoplasmic domain, (Semaphorin) 6C isoform X1",
        "protein_names_refseq": "sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:556743)",
        "pathway_count": 1,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0030215 semaphorin receptor binding;GO:0045499 chemorepellent activity",
        "go_cellular_component": "",
        "go_biological_process": "GO:0007399 nervous system development",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HGM6-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HI94-1",
        "uniprot_id": "A0AC58HI94_DANRE",
        "mass": 71077.0,
        "length": 637,
        "protein_name": "alpha-1,2-Mannosidase",
        "gene_name": "LOC101882461",
        "organism": "Zebrafish",
        "refseq_name": "mannosyl-oligosaccharide 1,2-alpha-mannosidase IA isoform X1",
        "refseq_ac": "XP_073781661",
        "gene_names_uniprotkb": "LOC101882461",
        "gene_names_refseq": "LOC101882461",
        "protein_names_uniprotkb": "alpha-1,2-Mannosidase; 3.2.1.-",
        "protein_names_refseq": "mannosyl-oligosaccharide 1,2-alpha-mannosidase IA isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:101882461)",
        "pathway_count": 1,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2)., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 1,
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        "secondary_ac_list": "",
        "ec_number_list": "3.2.1.-",
        "go_molecular_function": "GO:0005509 calcium ion binding;GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity",
        "go_cellular_component": "GO:0016020 membrane;GO:0012505 endomembrane system",
        "go_biological_process": "GO:0005975 carbohydrate metabolic process",
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        "record_id": "A0AC58HI94-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HGI7-1",
        "uniprot_id": "A0AC58HGI7_DANRE",
        "mass": 53517.0,
        "length": 466,
        "protein_name": "Lysophospholipid acyltransferase 5",
        "gene_name": "lpcat3",
        "organism": "Zebrafish",
        "refseq_name": "lysophospholipid acyltransferase 5 isoform X1",
        "refseq_ac": "XP_073781106",
        "gene_names_uniprotkb": "lpcat3; im:7145298; si:dkey-197a20.5",
        "gene_names_refseq": "im:7145298; lpcat3; si:dkey-197a20.5",
        "protein_names_uniprotkb": "Lysophospholipid acyltransferase 5; 2.3.1.23; 2.3.1.n6",
        "protein_names_refseq": "lysophospholipid acyltransferase 5 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:555566)",
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        "publication_count": 4,
        "publication_id_list": "26083432;30863400;37043308;37714372",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "go_molecular_function": "GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity;GO:0016746 acyltransferase activity",
        "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane",
        "go_biological_process": "GO:0008654 phospholipid biosynthetic process",
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        "hit_score": 0.5,
        "record_id": "A0AC58HGI7-1",
        "record_type": "protein"
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        "uniprot_id": "A0AC58HH61_DANRE",
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        "length": 314,
        "protein_name": "Apolipoprotein A-IV b, tandem duplicate 2 isoform X1",
        "gene_name": "apoa4b.2; apoa4b.3",
        "organism": "Zebrafish",
        "refseq_name": "apolipoprotein A-IV b, tandem duplicate 2 isoform X1",
        "refseq_ac": "XP_073781327",
        "gene_names_uniprotkb": "apoa4b.2; apoa4b.3; apoa4b.2; fc28d04; si:dkey-7f3.15; wu:fc10a03; wu:fc28d04; zgc:194131",
        "gene_names_refseq": "apoa4b.2; fc28d04; wu:fc10a03; wu:fc28d04; zgc:194131",
        "protein_names_uniprotkb": "Apolipoprotein A-IV b, tandem duplicate 2 isoform X1",
        "protein_names_refseq": "apolipoprotein A-IV b, tandem duplicate 2 isoform X1",
        "tax_id": 7955,
        "disease": "chronic pancreatitis (Disease Ontology:DOID:0051065); colitis (Disease Ontology:DOID:0060180); autosomal dominant tubulointerstitial kidney disease 6 (Disease Ontology:DOID:0061121); graft-versus-host disease (Disease Ontology:DOID:0081267); Alzheimer's disease (Disease Ontology:DOID:10652); hyperlipoproteinemia type V (Disease Ontology:DOID:1171); hyperlipoproteinemia type IV (Disease Ontology:DOID:1172); Guillain-Barre syndrome (Disease Ontology:DOID:12842); Huntington's disease (Disease Ontology:DOID:12858); cardiovascular system disease (Disease Ontology:DOID:1287); polyneuropathy (Disease Ontology:DOID:1389); major depressive disorder (Disease Ontology:DOID:1470); glaucoma (Disease Ontology:DOID:1686); relapsing-remitting multiple sclerosis (Disease Ontology:DOID:2378); coronary artery disease (Disease Ontology:DOID:3393); cerebral infarction (Disease Ontology:DOID:3526); retinal detachment (Disease Ontology:DOID:5327); schizophrenia (Disease Ontology:DOID:5419); myocardial infarction (Disease Ontology:DOID:5844); hepatocellular carcinoma (Disease Ontology:DOID:684); Leber hereditary optic neuropathy (Disease Ontology:DOID:705); rheumatoid arthritis (Disease Ontology:DOID:7148); chronic kidney disease (Disease Ontology:DOID:784); ulcerative colitis (Disease Ontology:DOID:8577); Crohn's disease (Disease Ontology:DOID:8778); intermediate coronary syndrome (Disease Ontology:DOID:8805); diabetic retinopathy (Disease Ontology:DOID:8947); type 2 diabetes mellitus (Disease Ontology:DOID:9352); neovascular inflammatory vitreoretinopathy (Disease Ontology:DOID:9719)",
        "pathway": " (dre:100004607)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "25633982;26469318;27189481;27655916;28252024;31022537;32094353;33513687;34968768;39528516",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 29,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "A0AC58HH79",
        "ec_number_list": "",
        "go_molecular_function": "GO:0008289 lipid binding",
        "go_cellular_component": "GO:0005576 extracellular region",
        "go_biological_process": "GO:0006869 lipid transport;GO:0042157 lipoprotein metabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0AC58HH61-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HHC8-1",
        "uniprot_id": "A0AC58HHC8_DANRE",
        "mass": 29009.0,
        "length": 260,
        "protein_name": "Acyl-coenzyme A thioesterase THEM4",
        "gene_name": "them4",
        "organism": "Zebrafish",
        "refseq_name": "acyl-coenzyme A thioesterase THEM4 isoform X1",
        "refseq_ac": "XP_073781427",
        "gene_names_uniprotkb": "them4; zgc:158847",
        "gene_names_refseq": "them4; zgc:158847",
        "protein_names_uniprotkb": "Acyl-coenzyme A thioesterase THEM4; 3.1.2.2; Thioesterase superfamily member 4",
        "protein_names_refseq": "acyl-coenzyme A thioesterase THEM4 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:791152)",
        "pathway_count": 1,
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        "publication_id_list": "26469318",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": "3.1.2.2;3.1.2.22",
        "go_molecular_function": "GO:0016787 hydrolase activity",
        "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005758 mitochondrial intermembrane space;GO:0032587 ruffle membrane",
        "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0006915 apoptotic process",
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        "hit_score": 0.2,
        "record_id": "A0AC58HHC8-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HI19-1",
        "uniprot_id": "A0AC58HI19_DANRE",
        "mass": 108304.0,
        "length": 957,
        "protein_name": "non-specific serine/threonine protein kinase",
        "gene_name": "LOC100007785",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073781599",
        "gene_names_uniprotkb": "LOC100007785",
        "gene_names_refseq": "LOC100007785",
        "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100007785)",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": "2.7.11.1;2.7.11.13;2.7.11.25;2.7.10.1;2.7.11.22;2.7.11.21;2.7.11.17;2.7.12.1;2.7.12.2;2.7.11.24;2.7.10.2;2.7.11.23;2.7.1.150;2.7.11.12;2.7.11.39;2.7.11.11;2.7.1.153;2.7.1.137;2.7.1.154;2.7.11.26;2.7.11.31",
        "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding",
        "go_cellular_component": "GO:0005737 cytoplasm",
        "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0007346 regulation of mitotic cell cycle",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HI19-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HHV4-1",
        "uniprot_id": "A0AC58HHV4_DANRE",
        "mass": 65658.0,
        "length": 598,
        "protein_name": "Solute carrier family 40 member",
        "gene_name": "si:ch211-254p10.2",
        "organism": "Zebrafish",
        "refseq_name": "ferroportin isoform X1",
        "refseq_ac": "XP_073781536",
        "gene_names_uniprotkb": "si:ch211-254p10.2",
        "gene_names_refseq": "si:ch211-254p10.2",
        "protein_names_uniprotkb": "Solute carrier family 40 member",
        "protein_names_refseq": "ferroportin isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100151035)",
        "pathway_count": 1,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in iron transport and iron homeostasis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "missing_score": 10000,
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        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "GO:0005381 iron ion transmembrane transporter activity",
        "go_cellular_component": "GO:0016020 membrane",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HHV4-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HFV8-1",
        "uniprot_id": "A0AC58HFV8_DANRE",
        "mass": 89414.0,
        "length": 787,
        "protein_name": "Uncharacterized protein si:ch211-153l6.6 isoform X1",
        "gene_name": "si:ch211-153l6.6",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:ch211-153l6.6 isoform X1",
        "refseq_ac": "XP_073780873",
        "gene_names_uniprotkb": "si:ch211-153l6.6",
        "gene_names_refseq": "si:ch211-153l6.6",
        "protein_names_uniprotkb": "Uncharacterized protein si:ch211-153l6.6 isoform X1",
        "protein_names_refseq": "uncharacterized protein si:ch211-153l6.6 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:101884986)",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HFV8-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58HFX7-1",
        "uniprot_id": "A0AC58HFX7_DANRE",
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        "length": 683,
        "protein_name": "MAGUK p55 subfamily member 6a isoform X2",
        "gene_name": "pals2a",
        "organism": "Zebrafish",
        "refseq_name": "MAGUK p55 subfamily member 6a isoform X2",
        "refseq_ac": "XP_073780864",
        "gene_names_uniprotkb": "pals2a; im:6899520; mpp6a",
        "gene_names_refseq": "im:6899520; mpp6a; pals2a",
        "protein_names_uniprotkb": "MAGUK p55 subfamily member 6a isoform X2",
        "protein_names_refseq": "MAGUK p55 subfamily member 6a isoform X2",
        "tax_id": 7955,
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        "pathway": " (dre:402878)",
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        "publication_id_list": "26469318;27189481;28252024;29809138;31852739",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "go_molecular_function": "",
        "go_cellular_component": "GO:0016020 membrane;GO:0043226 organelle;GO:0005886 plasma membrane;GO:0005911 cell-cell junction",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.6,
        "record_id": "A0AC58HFX7-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HGB3-1",
        "uniprot_id": "A0AC58HGB3_DANRE",
        "mass": 46550.0,
        "length": 425,
        "protein_name": "Cell adhesion molecule 4",
        "gene_name": "cadm4",
        "organism": "Zebrafish",
        "refseq_name": "cell adhesion molecule 4 isoform X1",
        "refseq_ac": "XP_073781010",
        "gene_names_uniprotkb": "cadm4; zgc:101704",
        "gene_names_refseq": "cadm4; zgc:101704",
        "protein_names_uniprotkb": "Cell adhesion molecule 4; Immunoglobulin superfamily member 4C",
        "protein_names_refseq": "cell adhesion molecule 4 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:492787)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "18095341;20802085;20935258;21456004;24813897;28392072;29195096;30924555;31014480;33621777",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor-suppressor activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "GO:0043184 vascular endothelial growth factor receptor 2 binding",
        "go_cellular_component": "GO:0016020 membrane;GO:0044291 cell-cell contact zone",
        "go_biological_process": "GO:0021782 glial cell development;GO:0007155 cell adhesion;GO:0060041 retina development in camera-type eye;GO:0003234 bulbus arteriosus formation;GO:0061041 regulation of wound healing",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0AC58HGB3-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HG08-1",
        "uniprot_id": "A0AC58HG08_DANRE",
        "mass": 112980.0,
        "length": 984,
        "protein_name": "Toll-like receptor 19 isoform X1",
        "gene_name": "tlr19.1",
        "organism": "Zebrafish",
        "refseq_name": "toll-like receptor 19 isoform X1",
        "refseq_ac": "XP_073780929",
        "gene_names_uniprotkb": "tlr19.1; LOC137487195; tlr19",
        "gene_names_refseq": "tlr19.1; tlr19",
        "protein_names_uniprotkb": "Toll-like receptor 19 isoform X1",
        "protein_names_refseq": "toll-like receptor 19 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:137487195);  (dre:403134)",
        "pathway_count": 2,
        "publication_count": 5,
        "publication_id_list": "14687934;18248169;23880453;24327191;38055273",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "go_molecular_function": "GO:0038023 signaling receptor activity",
        "go_cellular_component": "GO:0016020 membrane;GO:0005886 plasma membrane",
        "go_biological_process": "GO:0006954 inflammatory response;GO:0007165 signal transduction;GO:0045087 innate immune response;GO:0002224 toll-like receptor signaling pathway",
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        "record_id": "A0AC58HG08-1",
        "record_type": "protein"
    },
    {
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        "uniprot_id": "A0AC58HI33_DANRE",
        "mass": 26556.0,
        "length": 239,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC103908925",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073781611",
        "gene_names_uniprotkb": "LOC103908925",
        "gene_names_refseq": "LOC103908925",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:103908925)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "secondary_ac_list": "",
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        "go_molecular_function": "GO:0003676 nucleic acid binding;GO:0004523 RNA-DNA hybrid ribonuclease activity;GO:0016779 nucleotidyltransferase activity",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HI33-1",
        "record_type": "protein"
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        "uniprot_id": "A0AC58HH25_DANRE",
        "mass": 10994.0,
        "length": 101,
        "protein_name": "FXYD domain-containing ion transport regulator",
        "gene_name": "fxyd6l",
        "organism": "Zebrafish",
        "refseq_name": "FXYD domain containing ion transport regulator 6 like isoform X1",
        "refseq_ac": "XP_073781285",
        "gene_names_uniprotkb": "fxyd6l",
        "gene_names_refseq": "fxyd6l",
        "protein_names_uniprotkb": "FXYD domain-containing ion transport regulator",
        "protein_names_refseq": "FXYD domain containing ion transport regulator 6 like isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:566443)",
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        "publication_id_list": "17541769;21423371;27189481;40044042",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "secondary_ac_list": "A0AC58HH42",
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        "go_molecular_function": "GO:0099106 ion channel regulator activity",
        "go_cellular_component": "GO:0016020 membrane",
        "go_biological_process": "GO:0006811 monoatomic ion transport;GO:0043269 regulation of monoatomic ion transport",
        "synthesized_glycan_count": 0,
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        "record_id": "A0AC58HH25-1",
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    },
    {
        "uniprot_canonical_ac": "A0AC58HG02-1",
        "uniprot_id": "A0AC58HG02_DANRE",
        "mass": 107161.0,
        "length": 934,
        "protein_name": "Toll-like receptor 18 isoform X1",
        "gene_name": "tlr18",
        "organism": "Zebrafish",
        "refseq_name": "toll-like receptor 18 isoform X1",
        "refseq_ac": "XP_073780916",
        "gene_names_uniprotkb": "tlr18; TLR1.2",
        "gene_names_refseq": "TLR1.2; tlr18",
        "protein_names_uniprotkb": "Toll-like receptor 18 isoform X1",
        "protein_names_refseq": "toll-like receptor 18 isoform X1",
        "tax_id": 7955,
        "disease": "glucose metabolism disease (Disease Ontology:DOID:4194); primary immunodeficiency disease (Disease Ontology:DOID:612); collagen disease (Disease Ontology:DOID:854)",
        "pathway": " (dre:403133)",
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        "publication_count": 10,
        "publication_id_list": "14687933;14687934;16552074;18248169;23598338;31372513;32554491;34130754;35829917;38882496",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0038023 signaling receptor activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0002224 toll-like receptor signaling pathway",
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    {
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        "length": 975,
        "protein_name": "ADAMTS-like protein 2 isoform X1",
        "gene_name": "si:ch211-267e7.3",
        "organism": "Zebrafish",
        "refseq_name": "ADAMTS-like protein 2 isoform X1",
        "refseq_ac": "XP_073780948",
        "gene_names_uniprotkb": "si:ch211-267e7.3",
        "gene_names_refseq": "si:ch211-267e7.3",
        "protein_names_uniprotkb": "ADAMTS-like protein 2 isoform X1",
        "protein_names_refseq": "ADAMTS-like protein 2 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:567853)",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "go_molecular_function": "GO:0004222 metalloendopeptidase activity",
        "go_cellular_component": "GO:0005576 extracellular region;GO:0031012 extracellular matrix",
        "go_biological_process": "GO:0030198 extracellular matrix organization;GO:0006508 proteolysis",
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    {
        "uniprot_canonical_ac": "A0AC58HG74-1",
        "uniprot_id": "A0AC58HG74_DANRE",
        "mass": 68447.0,
        "length": 618,
        "protein_name": "DNA repair protein XRCC1",
        "gene_name": "xrcc1",
        "organism": "Zebrafish",
        "refseq_name": "DNA repair protein XRCC1",
        "refseq_ac": "NP_001003988",
        "gene_names_uniprotkb": "xrcc1; zgc:91996",
        "gene_names_refseq": "xrcc1; zgc:91996",
        "protein_names_uniprotkb": "DNA repair protein XRCC1; X-ray repair cross-complementing protein 1",
        "protein_names_refseq": "DNA repair protein XRCC1; X-ray repair complementing defective repair in Chinese hamster cells 1",
        "tax_id": 7955,
        "disease": "colorectal adenocarcinoma (Disease Ontology:DOID:0050861); myelodysplastic syndrome (Disease Ontology:DOID:0050908); brain glioma (Disease Ontology:DOID:0060108); colorectal carcinoma (Disease Ontology:DOID:0080199); autosomal recessive spinocerebellar ataxia 26 (Disease Ontology:DOID:0080260); prostate cancer (Disease Ontology:DOID:10283); stomach cancer (Disease Ontology:DOID:10534); hypertension (Disease Ontology:DOID:10763); urinary bladder cancer (Disease Ontology:DOID:11054); asphyxia neonatorum (Disease Ontology:DOID:11088); hepatitis A (Disease Ontology:DOID:12549); leiomyoma (Disease Ontology:DOID:127); lung cancer (Disease Ontology:DOID:1324); malignant mesothelioma (Disease Ontology:DOID:1790); pancreatic cancer (Disease Ontology:DOID:1793); impotence (Disease Ontology:DOID:1875); hepatitis B (Disease Ontology:DOID:2043); transient cerebral ischemia (Disease Ontology:DOID:224); laryngeal carcinoma (Disease Ontology:DOID:2600); transitional cell carcinoma (Disease Ontology:DOID:2671); contact dermatitis (Disease Ontology:DOID:2773); invasive ductal carcinoma (Disease Ontology:DOID:3008); glioblastoma (Disease Ontology:DOID:3068); high grade glioma (Disease Ontology:DOID:3070); gallbladder cancer (Disease Ontology:DOID:3121); coronary artery disease (Disease Ontology:DOID:3393); middle cerebral artery infarction (Disease Ontology:DOID:3525); meningioma (Disease Ontology:DOID:3565); liver cancer (Disease Ontology:DOID:3571); central nervous system cancer (Disease Ontology:DOID:3620); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); papillary thyroid carcinoma (Disease Ontology:DOID:3969); cervical cancer (Disease Ontology:DOID:4362); seminoma (Disease Ontology:DOID:4440); renal cell carcinoma (Disease Ontology:DOID:4450); esophageal cancer (Disease Ontology:DOID:5041); liver cirrhosis (Disease Ontology:DOID:5082); stomach carcinoma (Disease Ontology:DOID:5517); gastric cardia carcinoma (Disease Ontology:DOID:6270); gastric cardia adenocarcinoma (Disease Ontology:DOID:6271); hepatocellular carcinoma (Disease Ontology:DOID:684); chronic myeloid leukemia (Disease Ontology:DOID:8552); in situ carcinoma (Disease Ontology:DOID:8719); diabetic retinopathy (Disease Ontology:DOID:8947); colorectal cancer (Disease Ontology:DOID:9256); nasopharynx carcinoma (Disease Ontology:DOID:9261); type 2 diabetes mellitus (Disease Ontology:DOID:9352); oral mucosa leukoplakia (Disease Ontology:DOID:9655); senile cataract (Disease Ontology:DOID:9669); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)",
        "pathway": " (R-DRE-110381);  (R-DRE-5649702);  (R-DRE-5685939);  (R-DRE-6782210)",
        "pathway_count": 4,
        "publication_count": 7,
        "publication_id_list": "24240475;26469318;29751158;30791195;31561131;33120273;34390914",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: GDQH01001236.1, SRR32588727.2471067.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708828, SAMEA708836 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1. On or before Jul 17, 2025 this sequence version replaced XP_073780994.1, NP_001003988.2. Sequence Note:., [RefSeq]; Scaffold protein involved in DNA single-strand break repair by mediating the assembly of DNA break repair protein complexes. Negatively regulates ADP-ribosyltransferase activity of PARP1 during base-excision repair in order to prevent excessive PARP1 activity. Recognizes and binds poly-ADP-ribose chains: specifically binds auto-poly-ADP-ribosylated PARP1, limiting its activity., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "disease_count": 52,
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        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "GO:0003684 damaged DNA binding",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome",
        "go_biological_process": "GO:0006284 base-excision repair;GO:0006303 double-strand break repair via nonhomologous end joining;GO:0000012 single strand break repair",
        "synthesized_glycan_count": 0,
        "hit_score": 0.8,
        "record_id": "A0AC58HG74-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HF78-1",
        "uniprot_id": "A0AC58HF78_DANRE",
        "mass": 60014.0,
        "length": 543,
        "protein_name": "G protein-activated inward rectifier potassium channel 3",
        "gene_name": "kcnj14",
        "organism": "Zebrafish",
        "refseq_name": "",
        "refseq_ac": "",
        "gene_names_uniprotkb": "kcnj14; si:ch211-120k19.4",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "G protein-activated inward rectifier potassium channel 3; Inward rectifier K(+) channel Kir3.3; Potassium channel, inwardly rectifying subfamily J member 9",
        "protein_names_refseq": "",
        "tax_id": 7955,
        "disease": "EAST syndrome (Disease Ontology:DOID:0060484)",
        "pathway": " (dre:100526806);  (R-DRE-1296053);  (R-DRE-5576886)",
        "pathway_count": 3,
        "publication_count": 5,
        "publication_id_list": "25991088;27189481;31679058;31934309;34558132",
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        "ec_number_list": "2.7.11.1;1.5.1.2",
        "go_molecular_function": "GO:0005242 inward rectifier potassium channel activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0034702 monoatomic ion channel complex",
        "go_biological_process": "GO:0007399 nervous system development;GO:1990573 potassium ion import across plasma membrane;GO:0043010 camera-type eye development;GO:0034220 monoatomic ion transmembrane transport",
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        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HF17-1",
        "uniprot_id": "A0AC58HF17_DANRE",
        "mass": 101282.0,
        "length": 886,
        "protein_name": "Autotaxin isoform X2",
        "gene_name": "enpp2",
        "organism": "Zebrafish",
        "refseq_name": "autotaxin isoform X2",
        "refseq_ac": "XP_073780584",
        "gene_names_uniprotkb": "enpp2; atxa; atx; zgc:63550",
        "gene_names_refseq": "atxa; atx; enpp2; zgc:63550",
        "protein_names_uniprotkb": "Autotaxin isoform X2",
        "protein_names_refseq": "autotaxin isoform X2",
        "tax_id": 7955,
        "disease": "proliferative diabetic retinopathy (Disease Ontology:DOID:13207)",
        "pathway": "",
        "pathway_count": 0,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "ec_number_list": "3.1.4.4;3.1.4.39",
        "go_molecular_function": "GO:0030247 polysaccharide binding;GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity;GO:0004630 phospholipase D activity;GO:0005044 scavenger receptor activity;GO:0008270 zinc ion binding",
        "go_cellular_component": "GO:0005615 extracellular space",
        "go_biological_process": "GO:0034638 phosphatidylcholine catabolic process;GO:0060217 hemangioblast cell differentiation;GO:0006935 chemotaxis;GO:0006955 immune response;GO:0060271 cilium assembly",
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        "record_id": "A0AC58HF17-1",
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    },
    {
        "uniprot_canonical_ac": "A0AC58HG58-1",
        "uniprot_id": "A0AC58HG58_DANRE",
        "mass": 58795.0,
        "length": 513,
        "protein_name": "Diacylglycerol O-acyltransferase 1b isoform X1",
        "gene_name": "dgat1b",
        "organism": "Zebrafish",
        "refseq_name": "diacylglycerol O-acyltransferase 1b isoform X1",
        "refseq_ac": "XP_073780971",
        "gene_names_uniprotkb": "dgat1b; zgc:92327",
        "gene_names_refseq": "dgat1b; zgc:92327",
        "protein_names_uniprotkb": "Diacylglycerol O-acyltransferase 1b isoform X1",
        "protein_names_refseq": "diacylglycerol O-acyltransferase 1b isoform X1",
        "tax_id": 7955,
        "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); congenital diarrhea 7 with exudative enteropathy (Disease Ontology:DOID:0060778); nephrotic syndrome (Disease Ontology:DOID:1184); chronic kidney disease (Disease Ontology:DOID:784)",
        "pathway": "",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "ec_number_list": "3.1.1.23;3.1.1.79;2.3.1.20;2.3.1.76",
        "go_molecular_function": "GO:0004144 diacylglycerol O-acyltransferase activity;GO:0050252 retinol O-fatty-acyltransferase activity",
        "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane",
        "go_biological_process": "GO:0001878 response to yeast;GO:0019432 triglyceride biosynthetic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HG58-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HI21-1",
        "uniprot_id": "A0AC58HI21_DANRE",
        "mass": 41171.0,
        "length": 366,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC101885445",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073781600",
        "gene_names_uniprotkb": "LOC101885445",
        "gene_names_refseq": "LOC101885445",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:101885445)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "",
        "go_cellular_component": "GO:0005886 plasma membrane",
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        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HI21-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58HG91-1",
        "uniprot_id": "A0AC58HG91_DANRE",
        "mass": 42129.0,
        "length": 379,
        "protein_name": "Thioredoxin-interacting protein",
        "gene_name": "txnipb",
        "organism": "Zebrafish",
        "refseq_name": "thioredoxin interacting protein b isoform X1",
        "refseq_ac": "XP_073781002",
        "gene_names_uniprotkb": "txnipb; txnipl",
        "gene_names_refseq": "txnipb; txnipl",
        "protein_names_uniprotkb": "Thioredoxin-interacting protein",
        "protein_names_refseq": "thioredoxin interacting protein b isoform X1",
        "tax_id": 7955,
        "disease": "Reye syndrome (Disease Ontology:DOID:14525); hepatocellular carcinoma (Disease Ontology:DOID:684)",
        "pathway": " (dre:448858)",
        "pathway_count": 1,
        "publication_count": 7,
        "publication_id_list": "24683187;26040990;26061167;26469318;31319311;33159854;36403304",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1)., [UniProtKB, UniProtKB, UniProtKB]",
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        "missing_score": 10000,
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        "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0004857 enzyme inhibitor activity",
        "go_cellular_component": "GO:0005737 cytoplasm",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006979 response to oxidative stress;GO:0007399 nervous system development",
        "synthesized_glycan_count": 0,
        "hit_score": 0.8,
        "record_id": "A0AC58HG91-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58HHS3-1",
        "uniprot_id": "A0AC58HHS3_DANRE",
        "mass": 54365.0,
        "length": 472,
        "protein_name": "Chimaerin",
        "gene_name": "chn2",
        "organism": "Zebrafish",
        "refseq_name": "beta-chimaerin isoform X1",
        "refseq_ac": "XP_073781591",
        "gene_names_uniprotkb": "chn2",
        "gene_names_refseq": "chn2",
        "protein_names_uniprotkb": "Chimaerin; Chimerin",
        "protein_names_refseq": "beta-chimaerin isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (R-DRE-9013149)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; GTPase-activating protein for p21-rac., [UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0008270 zinc ion binding",
        "go_cellular_component": "",
        "go_biological_process": "GO:0007165 signal transduction;GO:0007399 nervous system development;GO:0051056 regulation of small GTPase mediated signal transduction;GO:0001675 acrosome assembly",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HHS3-1",
        "record_type": "protein"
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    {
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        "uniprot_id": "A0AC58HHM4_DANRE",
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        "length": 1006,
        "protein_name": "Espin-like protein isoform X1",
        "gene_name": "espnlb",
        "organism": "Zebrafish",
        "refseq_name": "espin-like protein isoform X1",
        "refseq_ac": "XP_073781447",
        "gene_names_uniprotkb": "espnlb",
        "gene_names_refseq": "espnlb",
        "protein_names_uniprotkb": "Espin-like protein isoform X1",
        "protein_names_refseq": "espin-like protein isoform X1",
        "tax_id": 7955,
        "disease": "autosomal recessive nonsyndromic deafness 36 (Disease Ontology:DOID:0110494)",
        "pathway": " (dre:566645)",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "go_molecular_function": "GO:0051015 actin filament binding",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0032420 stereocilium",
        "go_biological_process": "GO:0051017 actin filament bundle assembly;GO:0007605 sensory perception of sound",
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        "hit_score": 0.1,
        "record_id": "A0AC58HHM4-1",
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    {
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        "uniprot_id": "A0AC58HHL9_DANRE",
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        "length": 293,
        "protein_name": "Zinc transporter ZIP3 isoform X1",
        "gene_name": "slc39a3",
        "organism": "Zebrafish",
        "refseq_name": "zinc transporter ZIP3 isoform X1",
        "refseq_ac": "XP_073781450",
        "gene_names_uniprotkb": "slc39a3; ZIP3; wu:fc84e09; zgc:158334",
        "gene_names_refseq": "ZIP3; slc39a3; wu:fc84e09; zgc:158334",
        "protein_names_uniprotkb": "Zinc transporter ZIP3 isoform X1",
        "protein_names_refseq": "zinc transporter ZIP3 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:792986)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "16500426;18477665;21596156;22912764;24532580;28837703;30851936;32015324;32423892;37068188",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "A0AC58HHM2",
        "ec_number_list": "",
        "go_molecular_function": "GO:0005385 zinc ion transmembrane transporter activity",
        "go_cellular_component": "GO:0016020 membrane",
        "go_biological_process": "GO:0006829 zinc ion transport;GO:0010043 response to zinc ion",
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        "hit_score": 1.1,
        "record_id": "A0AC58HHL9-1",
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    {
        "uniprot_canonical_ac": "A0AC58HHQ0-1",
        "uniprot_id": "A0AC58HHQ0_DANRE",
        "mass": 163476.0,
        "length": 1465,
        "protein_name": "non-specific serine/threonine protein kinase",
        "gene_name": "LOC561283",
        "organism": "Zebrafish",
        "refseq_name": "",
        "refseq_ac": "",
        "gene_names_uniprotkb": "LOC561283",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1",
        "protein_names_refseq": "",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:561283)",
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        "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1",
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        "length": 1008,
        "protein_name": "Dual specificity phosphatase 29",
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        "organism": "Zebrafish",
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        "protein_names_refseq": "uncharacterized protein isoform X2",
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        "protein_names_uniprotkb": "Brevican core protein",
        "protein_names_refseq": "brevican core protein isoform X1",
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        "protein_name": "Thrombospondin, type I, domain containing 7Ab isoform X1",
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        "protein_name": "Integrase catalytic domain-containing protein",
        "gene_name": "LOC137487776",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": "XP_073780621",
        "gene_names_uniprotkb": "LOC137487776",
        "gene_names_refseq": "LOC137487776",
        "protein_names_uniprotkb": "Integrase catalytic domain-containing protein",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "missing_score": 10000,
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        "record_id": "A0AC58HF99-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58HFM5-1",
        "uniprot_id": "A0AC58HFM5_DANRE",
        "mass": 29012.0,
        "length": 258,
        "protein_name": "Ras-related protein Rab-25",
        "gene_name": "rab11al",
        "organism": "Zebrafish",
        "refseq_name": "",
        "refseq_ac": "",
        "gene_names_uniprotkb": "rab11al; fc54g10; wu:fc54g10; zgc:63565",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Ras-related protein Rab-25",
        "protein_names_refseq": "",
        "tax_id": 7955,
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        "function": "The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB25 regulates epithelial cell differentiation, proliferation and survival, thereby playing key roles in tumorigenesis. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia. Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions. May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis., [UniProtKB, UniProtKB]",
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        "record_id": "A0AC58HFM5-1",
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    {
        "uniprot_canonical_ac": "A0AC58HG64-1",
        "uniprot_id": "A0AC58HG64_DANRE",
        "mass": 49094.0,
        "length": 452,
        "protein_name": "Riboflavin transporter",
        "gene_name": "slc52a3-2b",
        "organism": "Zebrafish",
        "refseq_name": "solute carrier family 52, riboflavin transporter, member 3-B isoform X1",
        "refseq_ac": "XP_073780967",
        "gene_names_uniprotkb": "slc52a3-2b; RFT2-B; rft2b; slc52a3b; zgc:91890",
        "gene_names_refseq": "RFT2-B; rft2b; slc52a3-2b; slc52a3b; zgc:91890",
        "protein_names_uniprotkb": "Riboflavin transporter",
        "protein_names_refseq": "solute carrier family 52, riboflavin transporter, member 3-B isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism., [UniProtKB, UniProtKB]",
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        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HG64-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58HG78-1",
        "uniprot_id": "A0AC58HG78_DANRE",
        "mass": 69384.0,
        "length": 614,
        "protein_name": "CTP synthase",
        "gene_name": "ctps1b",
        "organism": "Zebrafish",
        "refseq_name": "CTP synthase 1b isoform X2",
        "refseq_ac": "XP_073780993",
        "gene_names_uniprotkb": "ctps1b; ctpsb; zgc:100914",
        "gene_names_refseq": "ctps1b; ctpsb; zgc:100914",
        "protein_names_uniprotkb": "CTP synthase; 6.3.4.2; UTP--ammonia ligase",
        "protein_names_refseq": "CTP synthase 1b isoform X2",
        "tax_id": 7955,
        "disease": "biliary tract benign neoplasm (Disease Ontology:DOID:0050625); immunodeficiency 24 (Disease Ontology:DOID:0111938); colorectal cancer (Disease Ontology:DOID:9256)",
        "pathway": " (dre:445245)",
        "pathway_count": 1,
        "publication_count": 5,
        "publication_id_list": "19174480;23072875;30241946;34129847;36290180",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "ec_number_list": "6.3.4.2;3.5.1.-",
        "go_molecular_function": "GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0003883 CTP synthase activity",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0097268 cytoophidium",
        "go_biological_process": "GO:0030903 notochord development;GO:0044210 'de novo' CTP biosynthetic process;GO:0006241 CTP biosynthetic process;GO:0019856 pyrimidine nucleobase biosynthetic process",
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        "hit_score": 0.6,
        "record_id": "A0AC58HG78-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58HG85-1",
        "uniprot_id": "A0AC58HG85_DANRE",
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        "length": 2478,
        "protein_name": "Uncharacterized protein",
        "gene_name": "LOC141378041",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
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        "gene_names_uniprotkb": "LOC141378041",
        "gene_names_refseq": "LOC141378041",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "uncharacterized protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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    {
        "uniprot_canonical_ac": "A0AC58HGB0-1",
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        "length": 1909,
        "protein_name": "Nucleoprotein TPR",
        "gene_name": "LOC141378043",
        "organism": "Zebrafish",
        "refseq_name": "nucleoprotein TPR-like isoform X1",
        "refseq_ac": "XP_073781022",
        "gene_names_uniprotkb": "LOC141378043",
        "gene_names_refseq": "LOC141378043",
        "protein_names_uniprotkb": "Nucleoprotein TPR; NPC-associated intranuclear protein",
        "protein_names_refseq": "nucleoprotein TPR-like isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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    {
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        "protein_name": "Uncharacterized protein",
        "gene_name": "LOC141378044",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
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        "gene_names_uniprotkb": "LOC141378044",
        "gene_names_refseq": "LOC141378044",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "uncharacterized protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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    {
        "uniprot_canonical_ac": "A0AC58HI83-1",
        "uniprot_id": "A0AC58HI83_DANRE",
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        "length": 696,
        "protein_name": "CREB-regulated transcription coactivator 2 isoform X1",
        "gene_name": "LOC108179660",
        "organism": "Zebrafish",
        "refseq_name": "CREB-regulated transcription coactivator 2 isoform X1",
        "refseq_ac": "XP_073781741",
        "gene_names_uniprotkb": "LOC108179660",
        "gene_names_refseq": "LOC108179660",
        "protein_names_uniprotkb": "CREB-regulated transcription coactivator 2 isoform X1",
        "protein_names_refseq": "CREB-regulated transcription coactivator 2 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "record_id": "A0AC58HI83-1",
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    {
        "uniprot_canonical_ac": "A0AC58HI90-1",
        "uniprot_id": "A0AC58HI90_DANRE",
        "mass": 46147.0,
        "length": 420,
        "protein_name": "Cyclic AMP-responsive element-binding protein 3-like protein 4",
        "gene_name": "creb3l4",
        "organism": "Zebrafish",
        "refseq_name": "cyclic AMP-responsive element-binding protein 3-like protein 4",
        "refseq_ac": "XP_073781739",
        "gene_names_uniprotkb": "creb3l4",
        "gene_names_refseq": "creb3l4",
        "protein_names_uniprotkb": "Cyclic AMP-responsive element-binding protein 3-like protein 4",
        "protein_names_refseq": "cyclic AMP-responsive element-binding protein 3-like protein 4",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Transcriptional activator. Binds the cAMP response element (CRE). Activates transcription through box-B element and CRE. Seems to function synergistically with atf6. Regulates FGF21 transcription., [UniProtKB, UniProtKB]",
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        "secondary_ac_list": "A0AC58HIG1",
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        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HI90-1",
        "record_type": "protein"
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    {
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        "mass": 31252.0,
        "length": 275,
        "protein_name": "non-specific serine/threonine protein kinase",
        "gene_name": "LOC110439018",
        "organism": "Zebrafish",
        "refseq_name": "serine/threonine-protein kinase pim-2-like",
        "refseq_ac": "XP_073781693",
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        "gene_names_refseq": "LOC110439018",
        "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1",
        "protein_names_refseq": "serine/threonine-protein kinase pim-2-like",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "ec_number_list": "2.7.11.1;2.7.11.13;2.7.11.25;2.7.10.1;2.7.11.22;2.7.11.21;2.7.11.17;2.7.12.1;2.7.12.2;2.7.11.24;2.7.10.2;2.7.11.23;2.7.1.150;2.7.11.12;2.7.11.39;2.7.11.11;2.7.1.153;2.7.1.137;2.7.1.154;2.7.11.26;2.7.11.31",
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        "record_type": "protein"
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    {
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        "uniprot_id": "A0AC58HIA3_DANRE",
        "mass": 27257.0,
        "length": 227,
        "protein_name": "Serine/arginine-rich splicing factor 10",
        "gene_name": "srsf10a",
        "organism": "Zebrafish",
        "refseq_name": "serine/arginine-rich splicing factor 12 isoform X1",
        "refseq_ac": "XP_073781698",
        "gene_names_uniprotkb": "srsf10a",
        "gene_names_refseq": "srsf10a",
        "protein_names_uniprotkb": "Serine/arginine-rich splicing factor 10; FUS-interacting serine-arginine-rich protein 1; Splicing factor, arginine/serine-rich 13A; TLS-associated protein with Ser-Arg repeats; TLS-associated serine-arginine protein",
        "protein_names_refseq": "serine/arginine-rich splicing factor 12 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "uniprot_id": "A0AC58HI95_DANRE",
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        "length": 464,
        "protein_name": "Delayed-rectifier potassium channel regulatory subunit KCNS2",
        "gene_name": "kcns2",
        "organism": "Zebrafish",
        "refseq_name": "delayed-rectifier potassium channel regulatory subunit KCNS2",
        "refseq_ac": "XP_073781759",
        "gene_names_uniprotkb": "kcns2",
        "gene_names_refseq": "kcns2",
        "protein_names_uniprotkb": "Delayed-rectifier potassium channel regulatory subunit KCNS2",
        "protein_names_refseq": "delayed-rectifier potassium channel regulatory subunit KCNS2",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_biological_process": "GO:0034220 monoatomic ion transmembrane transport",
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        "uniprot_id": "A0AC58HI96_DANRE",
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        "length": 500,
        "protein_name": "Transmembrane protease serine 9 isoform X1",
        "gene_name": "LOC137487997",
        "organism": "Zebrafish",
        "refseq_name": "transmembrane protease serine 9 isoform X1",
        "refseq_ac": "XP_073781672",
        "gene_names_uniprotkb": "LOC137487997",
        "gene_names_refseq": "LOC137487997",
        "protein_names_uniprotkb": "Transmembrane protease serine 9 isoform X1",
        "protein_names_refseq": "transmembrane protease serine 9 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "GO:0008233 peptidase activity",
        "go_cellular_component": "",
        "go_biological_process": "GO:0006508 proteolysis",
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        "record_id": "A0AC58HI96-1",
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        "protein_name": "Ribonucleases P/MRP protein subunit POP1 isoform X1",
        "gene_name": "pop1",
        "organism": "Zebrafish",
        "refseq_name": "ribonucleases P/MRP protein subunit POP1 isoform X1",
        "refseq_ac": "XP_073781755",
        "gene_names_uniprotkb": "pop1",
        "gene_names_refseq": "pop1",
        "protein_names_uniprotkb": "Ribonucleases P/MRP protein subunit POP1 isoform X1",
        "protein_names_refseq": "ribonucleases P/MRP protein subunit POP1 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "gene_names_refseq": "LOC141378135",
        "protein_names_uniprotkb": "Dual specificity phosphatase 29; 3.1.3.16; 3.1.3.48; Dual specificity phosphatase DUPD1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
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        "pathway": "",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate. Involved in the modulation of AMPK and MAPK1/2 signaling pathways., [UniProtKB, UniProtKB, UniProtKB]",
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        "ec_number_list": "3.1.3.16;3.1.3.48;3.1.3.2;3.1.3.67;3.1.3.27;3.1.3.21",
        "go_molecular_function": "",
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        "synthesized_glycan_count": 0,
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        "record_id": "A0AC58HIF6-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HIH1-1",
        "uniprot_id": "A0AC58HIH1_DANRE",
        "mass": 31008.0,
        "length": 270,
        "protein_name": "non-specific serine/threonine protein kinase",
        "gene_name": "LOC108179664",
        "organism": "Zebrafish",
        "refseq_name": "serine/threonine-protein kinase pim-2-like",
        "refseq_ac": "XP_073781754",
        "gene_names_uniprotkb": "LOC108179664",
        "gene_names_refseq": "LOC108179664",
        "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1",
        "protein_names_refseq": "serine/threonine-protein kinase pim-2-like",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "ec_number_list": "2.7.11.1;2.7.11.13;2.7.11.25;2.7.10.1;2.7.11.22;2.7.11.21;2.7.11.17;2.7.12.1;2.7.12.2;2.7.11.24;2.7.10.2;2.7.11.23;2.7.1.150;2.7.11.12;2.7.11.39;2.7.11.11;2.7.1.153;2.7.1.137;2.7.1.154;2.7.11.26;2.7.11.31",
        "go_molecular_function": "",
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        "hit_score": 0.1,
        "record_id": "A0AC58HIH1-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HKV0-1",
        "uniprot_id": "A0AC58HKV0_DANRE",
        "mass": 101447.0,
        "length": 925,
        "protein_name": "Calcium-transporting ATPase",
        "gene_name": "atp2c1",
        "organism": "Zebrafish",
        "refseq_name": "calcium-transporting ATPase type 2C member 1 isoform X1",
        "refseq_ac": "XP_073782630",
        "gene_names_uniprotkb": "atp2c1",
        "gene_names_refseq": "atp2c1",
        "protein_names_uniprotkb": "Calcium-transporting ATPase; 7.2.2.10",
        "protein_names_refseq": "calcium-transporting ATPase type 2C member 1 isoform X1",
        "tax_id": 7955,
        "disease": "Hailey-Hailey disease (Disease Ontology:DOID:0050429)",
        "pathway": " (dre:559574);  (R-DRE-936837)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the hydrolysis of ATP coupled with the transport of calcium., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "ec_number_list": "7.2.2.10",
        "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0005388 P-type calcium transporter activity",
        "go_cellular_component": "GO:0032580 Golgi cisterna membrane;GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane",
        "go_biological_process": "GO:0006874 intracellular calcium ion homeostasis;GO:0006828 manganese ion transport;GO:0055071 manganese ion homeostasis;GO:0070588 calcium ion transmembrane transport",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HKV0-1",
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        "uniprot_id": "A0AC58HJ32_DANRE",
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        "protein_name": "Phosphodiesterase",
        "gene_name": "pde4ca",
        "organism": "Zebrafish",
        "refseq_name": "3',5'-cyclic-AMP phosphodiesterase 4C isoform X1",
        "refseq_ac": "XP_073781958",
        "gene_names_uniprotkb": "pde4ca",
        "gene_names_refseq": "pde4ca",
        "protein_names_uniprotkb": "Phosphodiesterase; 3.1.4.-",
        "protein_names_refseq": "3',5'-cyclic-AMP phosphodiesterase 4C isoform X1",
        "tax_id": 7955,
        "disease": "depressive disorder (Disease Ontology:DOID:1596)",
        "pathway": " (dre:565259)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "ec_number_list": "3.1.4.-;3.1.4.53",
        "go_molecular_function": "GO:0046872 metal ion binding;GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity;GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity",
        "go_cellular_component": "",
        "go_biological_process": "GO:0007165 signal transduction;GO:0006198 cAMP catabolic process;GO:0141162 negative regulation of cAMP/PKA signal transduction",
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        "hit_score": 0.1,
        "record_id": "A0AC58HJ32-1",
        "record_type": "protein"
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        "length": 1391,
        "protein_name": "non-specific serine/threonine protein kinase",
        "gene_name": "pik3r4",
        "organism": "Zebrafish",
        "refseq_name": "phosphoinositide 3-kinase regulatory subunit 4 isoform X1",
        "refseq_ac": "XP_073782553",
        "gene_names_uniprotkb": "pik3r4",
        "gene_names_refseq": "pik3r4",
        "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1",
        "protein_names_refseq": "phosphoinositide 3-kinase regulatory subunit 4 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:564088)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding",
        "go_cellular_component": "GO:0005776 autophagosome;GO:0071561 nucleus-vacuole junction;GO:0005770 late endosome;GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I;GO:0034272 phosphatidylinositol 3-kinase complex, class III, type II",
        "go_biological_process": "GO:0016236 macroautophagy;GO:0045324 late endosome to vacuole transport;GO:0006623 protein targeting to vacuole;GO:0000425 pexophagy",
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        "record_id": "A0AC58HKM8-1",
        "record_type": "protein"
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    {
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        "uniprot_id": "A0AC58HJB7_DANRE",
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        "length": 958,
        "protein_name": "Chloride channel protein 1 isoform X2",
        "gene_name": "clcn1b",
        "organism": "Zebrafish",
        "refseq_name": "chloride channel protein 1 isoform X2",
        "refseq_ac": "XP_073782104",
        "gene_names_uniprotkb": "clcn1b",
        "gene_names_refseq": "clcn1b",
        "protein_names_uniprotkb": "Chloride channel protein 1 isoform X2",
        "protein_names_refseq": "chloride channel protein 1 isoform X2",
        "tax_id": 7955,
        "disease": "Becker disease (Disease Ontology:DOID:0081335); Thomsen disease (Disease Ontology:DOID:0081336); myotonia congenita (Disease Ontology:DOID:2106); myopathy (Disease Ontology:DOID:423)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "secondary_ac_list": "A0AC58HJC7",
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        "go_molecular_function": "GO:0005247 voltage-gated chloride channel activity;GO:0005254 chloride channel activity",
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        "length": 4648,
        "protein_name": "Dynein axonemal heavy chain 5 isoform X1",
        "gene_name": "dnah5",
        "organism": "Zebrafish",
        "refseq_name": "dynein axonemal heavy chain 5 isoform X1",
        "refseq_ac": "XP_073781887",
        "gene_names_uniprotkb": "dnah5",
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        "protein_names_uniprotkb": "Dynein axonemal heavy chain 5 isoform X1",
        "protein_names_refseq": "dynein axonemal heavy chain 5 isoform X1",
        "tax_id": 7955,
        "disease": "Kartagener syndrome (Disease Ontology:DOID:0050144); visceral heterotaxy (Disease Ontology:DOID:0050545); primary ciliary dyskinesia 3 (Disease Ontology:DOID:0110599); sensorineural hearing loss (Disease Ontology:DOID:10003); otitis media (Disease Ontology:DOID:10754); tetralogy of Fallot (Disease Ontology:DOID:6419); primary ciliary dyskinesia (Disease Ontology:DOID:9562)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "missing_score": 10000,
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        "glycan_count": 0,
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        "go_molecular_function": "GO:0005524 ATP binding;GO:0008569 minus-end-directed microtubule motor activity;GO:0051959 dynein light intermediate chain binding;GO:0045505 dynein intermediate chain binding",
        "go_cellular_component": "GO:0005874 microtubule;GO:0036157 outer dynein arm;GO:0097729 9+2 motile cilium;GO:0005930 axoneme;GO:0030286 dynein complex",
        "go_biological_process": "GO:0060294 cilium movement involved in cell motility;GO:0036158 outer dynein arm assembly;GO:0007018 microtubule-based movement",
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        "record_type": "protein"
    },
    {
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        "uniprot_id": "A0AC58HIZ5_DANRE",
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        "length": 380,
        "protein_name": "Zinc-binding protein A33 isoform X1",
        "gene_name": "si:ch73-54f23.4",
        "organism": "Zebrafish",
        "refseq_name": "zinc-binding protein A33 isoform X1",
        "refseq_ac": "XP_073781980",
        "gene_names_uniprotkb": "si:ch73-54f23.4",
        "gene_names_refseq": "si:ch73-54f23.4",
        "protein_names_uniprotkb": "Zinc-binding protein A33 isoform X1",
        "protein_names_refseq": "zinc-binding protein A33 isoform X1",
        "tax_id": 7955,
        "disease": "myelodysplastic syndrome (Disease Ontology:DOID:0050908); Sweet syndrome (Disease Ontology:DOID:0080746); IgA vasculitis (Disease Ontology:DOID:11123); asthma (Disease Ontology:DOID:2841); familial Mediterranean fever (Disease Ontology:DOID:2987); lung disease (Disease Ontology:DOID:850); acute myeloid leukemia (Disease Ontology:DOID:9119); multiple myeloma (Disease Ontology:DOID:9538); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Uncharacterized protein C10orf67 homolog, mitochondrial isoform X1",
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        "gene_names_refseq": "si:dkey-188g12.1",
        "protein_names_uniprotkb": "Uncharacterized protein C10orf67 homolog, mitochondrial isoform X1",
        "protein_names_refseq": "uncharacterized protein C10orf67 homolog, mitochondrial isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Mirror-image polydactyly gene 1 protein isoform X1",
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        "gene_names_refseq": "hm:zeh0377; mipol1; zeh0377",
        "protein_names_uniprotkb": "Mirror-image polydactyly gene 1 protein isoform X1",
        "protein_names_refseq": "mirror-image polydactyly gene 1 protein isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Uncharacterized protein si:dkey-199f5.3 isoform X1",
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        "gene_names_refseq": "si:dkey-199f5.3",
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        "protein_names_refseq": "uncharacterized protein si:dkey-199f5.3 isoform X1",
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        "length": 145,
        "protein_name": "Uncharacterized protein si:rp71-77l1.2 isoform X1",
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        "refseq_name": "uncharacterized protein si:rp71-77l1.2 isoform X1",
        "refseq_ac": "XP_073782825",
        "gene_names_uniprotkb": "si:rp71-77l1.2",
        "gene_names_refseq": "si:rp71-77l1.2",
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        "protein_names_refseq": "uncharacterized protein si:rp71-77l1.2 isoform X1",
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        "predicted_glycosites": 1,
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        "go_cellular_component": "GO:0016020 membrane",
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        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "si:ch211-278p9.1",
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        "refseq_name": "uncharacterized protein isoform X1",
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        "gene_names_uniprotkb": "si:ch211-278p9.1",
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        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
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        "protein_name": "Protein TUNAR isoform X1",
        "gene_name": "tunar",
        "organism": "Zebrafish",
        "refseq_name": "protein TUNAR isoform X1",
        "refseq_ac": "XP_073783009",
        "gene_names_uniprotkb": "tunar; TUNA; linc86023; megamind",
        "gene_names_refseq": "TUNA; linc86023; megamind; tunar",
        "protein_names_uniprotkb": "Protein TUNAR isoform X1",
        "protein_names_refseq": "protein TUNAR isoform X1",
        "tax_id": 7955,
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        "pathway": " (dre:103909004)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC137487851",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073782665",
        "gene_names_uniprotkb": "LOC137487851",
        "gene_names_refseq": "LOC137487851",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "missing_score": 10000,
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    {
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        "length": 499,
        "protein_name": "Nuclear receptor ROR-alpha A-like isoform X1",
        "gene_name": "rorc",
        "organism": "Zebrafish",
        "refseq_name": "nuclear receptor ROR-alpha A-like isoform X1",
        "refseq_ac": "XP_073782127",
        "gene_names_uniprotkb": "rorc",
        "gene_names_refseq": "rorc",
        "protein_names_uniprotkb": "Nuclear receptor ROR-alpha A-like isoform X1",
        "protein_names_refseq": "nuclear receptor ROR-alpha A-like isoform X1",
        "tax_id": 7955,
        "disease": "immunodeficiency 42 (Disease Ontology:DOID:0111940); Sjogren's syndrome (Disease Ontology:DOID:12894); tuberculosis (Disease Ontology:DOID:399)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0004879 nuclear receptor activity",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HJG5-1",
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    {
        "uniprot_canonical_ac": "A0AC58HIK0-1",
        "uniprot_id": "A0AC58HIK0_DANRE",
        "mass": 23766.0,
        "length": 205,
        "protein_name": "Protein cornichon homolog 4 isoform X1",
        "gene_name": "cnih4",
        "organism": "Zebrafish",
        "refseq_name": "",
        "refseq_ac": "",
        "gene_names_uniprotkb": "cnih4",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "Protein cornichon homolog 4 isoform X1",
        "protein_names_refseq": "",
        "tax_id": 7955,
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        "missing_score": 10000,
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        "secondary_ac_list": "",
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        "go_molecular_function": "GO:0005102 signaling receptor binding",
        "go_cellular_component": "GO:0030134 COPII-coated ER to Golgi transport vesicle;GO:0005789 endoplasmic reticulum membrane",
        "go_biological_process": "GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HIK0-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HJ75-1",
        "uniprot_id": "A0AC58HJ75_DANRE",
        "mass": 217964.0,
        "length": 1984,
        "protein_name": "Glutamate receptor ionotropic, NMDA 2C",
        "gene_name": "grin2db",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein grin2db isoform X1",
        "refseq_ac": "XP_073782035",
        "gene_names_uniprotkb": "grin2db",
        "gene_names_refseq": "grin2db",
        "protein_names_uniprotkb": "Glutamate receptor ionotropic, NMDA 2C; Glutamate [NMDA] receptor subunit epsilon-3; N-methyl D-aspartate receptor subtype 2C",
        "protein_names_refseq": "uncharacterized protein grin2db isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "reported_c_glycosites_with_glycan": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": "2.7.11.1;1.5.1.2",
        "go_molecular_function": "GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential;GO:0004972 NMDA glutamate receptor activity",
        "go_cellular_component": "GO:0017146 NMDA selective glutamate receptor complex;GO:0005886 plasma membrane;GO:0098839 postsynaptic density membrane",
        "go_biological_process": "GO:0060079 excitatory postsynaptic potential;GO:0035249 synaptic transmission, glutamatergic;GO:0098655 monoatomic cation transmembrane transport;GO:0060291 long-term synaptic potentiation",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HJ75-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HJA9-1",
        "uniprot_id": "A0AC58HJA9_DANRE",
        "mass": 37975.0,
        "length": 348,
        "protein_name": "Voltage-dependent calcium channel gamma-7 subunit",
        "gene_name": "cacng7b",
        "organism": "Zebrafish",
        "refseq_name": "voltage-dependent calcium channel gamma-7 subunit isoform X1",
        "refseq_ac": "XP_073782032",
        "gene_names_uniprotkb": "cacng7b",
        "gene_names_refseq": "cacng7b",
        "protein_names_uniprotkb": "Voltage-dependent calcium channel gamma-7 subunit",
        "protein_names_refseq": "voltage-dependent calcium channel gamma-7 subunit isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100003278)",
        "pathway_count": 1,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2., [UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "go_molecular_function": "GO:0005245 voltage-gated calcium channel activity;GO:0016247 channel regulator activity",
        "go_cellular_component": "GO:0032281 AMPA glutamate receptor complex;GO:0098839 postsynaptic density membrane",
        "go_biological_process": "GO:0051968 positive regulation of synaptic transmission, glutamatergic;GO:0019226 transmission of nerve impulse;GO:0098970 postsynaptic neurotransmitter receptor diffusion trapping",
        "synthesized_glycan_count": 0,
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        "record_id": "A0AC58HJA9-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58HIW7-1",
        "uniprot_id": "A0AC58HIW7_DANRE",
        "mass": 42493.0,
        "length": 376,
        "protein_name": "1-acylglycerol-3-phosphate O-acyltransferase ABHD5",
        "gene_name": "abhd5a",
        "organism": "Zebrafish",
        "refseq_name": "1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform X1",
        "refseq_ac": "XP_073781930",
        "gene_names_uniprotkb": "abhd5a",
        "gene_names_refseq": "abhd5a",
        "protein_names_uniprotkb": "1-acylglycerol-3-phosphate O-acyltransferase ABHD5; 2.3.1.51; Abhydrolase domain-containing protein 5",
        "protein_names_refseq": "1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:566493)",
        "pathway_count": 1,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Coenzyme A-dependent lysophosphatidic acid acyltransferase that catalyzes the transfer of an acyl group on a lysophosphatidic acid. Functions preferentially with 1-oleoyl-lysophosphatidic acid followed by 1-palmitoyl-lysophosphatidic acid, 1-stearoyl-lysophosphatidic acid and 1-arachidonoyl-lysophosphatidic acid as lipid acceptor. Functions preferentially with arachidonoyl-CoA followed by oleoyl-CoA as acyl group donors. Functions in phosphatidic acid biosynthesis. May regulate the cellular storage of triacylglycerol through activation of the phospholipase PNPLA2. Involved in keratinocyte differentiation. Regulates lipid droplet fusion., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "ec_number_list": "2.3.1.51;2.3.1.15;2.3.1.23;2.3.1.67;2.3.1.25;2.3.1.-",
        "go_molecular_function": "GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0042171 lysophosphatidic acid acyltransferase activity;GO:0052689 carboxylic ester hydrolase activity;GO:0004620 phospholipase activity",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005811 lipid droplet",
        "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0030154 cell differentiation;GO:0008654 phospholipid biosynthetic process;GO:0006654 phosphatidic acid biosynthetic process;GO:0010898 positive regulation of triglyceride catabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HIW7-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HL81-1",
        "uniprot_id": "A0AC58HL81_DANRE",
        "mass": 165965.0,
        "length": 1489,
        "protein_name": "Regulating synaptic membrane exocytosis protein 2 isoform X1",
        "gene_name": "rims2a",
        "organism": "Zebrafish",
        "refseq_name": "regulating synaptic membrane exocytosis protein 2 isoform X1",
        "refseq_ac": "XP_073782743",
        "gene_names_uniprotkb": "rims2a",
        "gene_names_refseq": "rims2a",
        "protein_names_uniprotkb": "Regulating synaptic membrane exocytosis protein 2 isoform X1",
        "protein_names_refseq": "regulating synaptic membrane exocytosis protein 2 isoform X1",
        "tax_id": 7955,
        "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041); schizophrenia (Disease Ontology:DOID:5419)",
        "pathway": " (dre:393672)",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "go_molecular_function": "GO:0031267 small GTPase binding",
        "go_cellular_component": "GO:0016020 membrane;GO:0045202 synapse",
        "go_biological_process": "GO:0006887 exocytosis",
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        "hit_score": 0.1,
        "record_id": "A0AC58HL81-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HKB0-1",
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        "mass": 75712.0,
        "length": 688,
        "protein_name": "non-specific serine/threonine protein kinase",
        "gene_name": "LOC101885829",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073782395",
        "gene_names_uniprotkb": "LOC101885829",
        "gene_names_refseq": "LOC101885829",
        "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
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        "pathway": " (dre:101885829)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "",
        "ec_number_list": "2.7.11.1;2.7.11.13;2.7.11.25;2.7.10.1;2.7.11.22;2.7.11.21;2.7.11.17;2.7.12.1;2.7.12.2;2.7.11.24;2.7.10.2;2.7.11.23;2.7.1.150;2.7.11.12;2.7.11.39;2.7.11.11;2.7.1.153;2.7.1.137;2.7.1.154;2.7.11.26;2.7.11.31",
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        "record_id": "A0AC58HKB0-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58HKR7-1",
        "uniprot_id": "A0AC58HKR7_DANRE",
        "mass": 74475.0,
        "length": 689,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC101885539",
        "organism": "Zebrafish",
        "refseq_name": "T-cell differentiation antigen CD6 isoform 6 precursor",
        "refseq_ac": "NP_001430310",
        "gene_names_uniprotkb": "LOC101885539",
        "gene_names_refseq": "LOC101885539",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "T-cell differentiation antigen CD6 isoform 6 precursor",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:101885539)",
        "pathway_count": 1,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588718.13179075.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505375, SAMEA3505377 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1. On Sep 12, 2025 this sequence version replaced XP_073782596.1., [RefSeq]",
        "predicted_glycosites": 0,
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        "uniprot_id": "A0AC58HM56_DANRE",
        "mass": 26070.0,
        "length": 238,
        "protein_name": "Galectin",
        "gene_name": "lgals3b",
        "organism": "Zebrafish",
        "refseq_name": "galectin-3b isoform X1",
        "refseq_ac": "XP_073783081",
        "gene_names_uniprotkb": "lgals3b; Drgal3; fc90g02; lgals3l; wu:fc90g02; zgc:123117",
        "gene_names_refseq": "Drgal3; fc90g02; lgals3b; lgals3l; wu:fc90g02; zgc:123117",
        "protein_names_uniprotkb": "Galectin",
        "protein_names_refseq": "galectin-3b isoform X1",
        "tax_id": 7955,
        "disease": "COVID-19 (Disease Ontology:DOID:0080600); hypertension (Disease Ontology:DOID:10763); attention deficit hyperactivity disorder (Disease Ontology:DOID:1094); aortic valve stenosis (Disease Ontology:DOID:1712); colon cancer (Disease Ontology:DOID:219); brain ischemia (Disease Ontology:DOID:2316); asthma (Disease Ontology:DOID:2841); acute kidney failure (Disease Ontology:DOID:3021); high grade glioma (Disease Ontology:DOID:3070); liver cirrhosis (Disease Ontology:DOID:5082); congestive heart failure (Disease Ontology:DOID:6000); steatotic liver disease (Disease Ontology:DOID:9452); type 1 diabetes mellitus (Disease Ontology:DOID:9744)",
        "pathway": " (dre:325599)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "14693912;15750792;17884332;20571107;24683187;26469318;26767746;27189481;29666124;37590563",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "go_molecular_function": "GO:0019863 IgE binding;GO:0030246 carbohydrate binding",
        "go_cellular_component": "GO:0005576 extracellular region;GO:0005737 cytoplasm;GO:0005681 spliceosomal complex",
        "go_biological_process": "GO:0006397 mRNA processing;GO:0030154 cell differentiation;GO:0045087 innate immune response;GO:0008380 RNA splicing",
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        "hit_score": 1.1,
        "record_id": "A0AC58HM56-1",
        "record_type": "protein"
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        "uniprot_id": "A0AC58HLE7_DANRE",
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        "length": 678,
        "protein_name": "non-specific serine/threonine protein kinase",
        "gene_name": "LOC108179511",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073782818",
        "gene_names_uniprotkb": "LOC108179511",
        "gene_names_refseq": "LOC108179511",
        "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
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        "pathway": " (dre:108179511)",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "ec_number_list": "2.7.11.1;2.7.11.13;2.7.11.25;2.7.10.1;2.7.11.22;2.7.11.21;2.7.11.17;2.7.12.1;2.7.12.2;2.7.11.24;2.7.10.2;2.7.11.23;2.7.1.150;2.7.11.12;2.7.11.39;2.7.11.11;2.7.1.153;2.7.1.137;2.7.1.154;2.7.11.26;2.7.11.31",
        "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding",
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    {
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        "mass": 109533.0,
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        "protein_name": "Dual specificity phosphatase 29",
        "gene_name": "LOC108179555",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073781791",
        "gene_names_uniprotkb": "LOC108179555",
        "gene_names_refseq": "LOC108179555",
        "protein_names_uniprotkb": "Dual specificity phosphatase 29; 3.1.3.16; 3.1.3.48; Dual specificity phosphatase DUPD1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:108179555)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate. Involved in the modulation of AMPK and MAPK1/2 signaling pathways., [UniProtKB, UniProtKB, UniProtKB]",
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": "3.1.3.16;3.1.3.48;3.1.3.2;3.1.3.67;3.1.3.27;3.1.3.21",
        "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity;GO:0008138 protein tyrosine/serine/threonine phosphatase activity;GO:0004725 protein tyrosine phosphatase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HIM1-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HKI6-1",
        "uniprot_id": "A0AC58HKI6_DANRE",
        "mass": 35746.0,
        "length": 311,
        "protein_name": "non-specific serine/threonine protein kinase",
        "gene_name": "LOC137487942",
        "organism": "Zebrafish",
        "refseq_name": "serine/threonine-protein kinase pim-2-like isoform X1",
        "refseq_ac": "XP_073782448",
        "gene_names_uniprotkb": "LOC137487942; LOC141378256; LOC141378258; LOC141378263; LOC141378264; LOC141378265; LOC141378266; LOC141378267; LOC141378268; LOC141378269; LOC141378270; LOC141378271; LOC141378272; LOC141378274",
        "gene_names_refseq": "LOC141378256",
        "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1",
        "protein_names_refseq": "serine/threonine-protein kinase pim-2-like isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:137487942)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "secondary_ac_list": "A0AC58HKC2;A0AC58HKH5",
        "ec_number_list": "2.7.11.1;2.7.11.13;2.7.11.25;2.7.10.1;2.7.11.22;2.7.11.21;2.7.11.17;2.7.12.1;2.7.12.2;2.7.11.24;2.7.10.2;2.7.11.23;2.7.1.150;2.7.11.12;2.7.11.39;2.7.11.11;2.7.1.153;2.7.1.137;2.7.1.154;2.7.11.26;2.7.11.31",
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        "record_id": "A0AC58HKI6-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58HIJ8-1",
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        "length": 2086,
        "protein_name": "Microtubule-actin cross-linking factor 1, isoforms 6/7 isoform X1",
        "gene_name": "macf1b",
        "organism": "Zebrafish",
        "refseq_name": "microtubule-actin cross-linking factor 1, isoforms 6/7 isoform X1",
        "refseq_ac": "XP_073781849",
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        "gene_names_refseq": "macf1b",
        "protein_names_uniprotkb": "Microtubule-actin cross-linking factor 1, isoforms 6/7 isoform X1",
        "protein_names_refseq": "microtubule-actin cross-linking factor 1, isoforms 6/7 isoform X1",
        "tax_id": 7955,
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        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "secondary_ac_list": "A0AC58HIN7",
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        "synthesized_glycan_count": 0,
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        "record_id": "A0AC58HIJ8-1",
        "record_type": "protein"
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        "length": 590,
        "protein_name": "WD repeat-containing protein 26",
        "gene_name": "wdr26a",
        "organism": "Zebrafish",
        "refseq_name": "WD repeat-containing protein 26 isoform X1",
        "refseq_ac": "XP_073781793",
        "gene_names_uniprotkb": "wdr26a",
        "gene_names_refseq": "wdr26a",
        "protein_names_uniprotkb": "WD repeat-containing protein 26",
        "protein_names_refseq": "WD repeat-containing protein 26 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "uniprot_id": "A0AC58HIK4_DANRE",
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        "length": 528,
        "protein_name": "Lysophosphatidylcholine acyltransferase 1",
        "gene_name": "LOC101884921",
        "organism": "Zebrafish",
        "refseq_name": "lysophosphatidylcholine acyltransferase 1",
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        "gene_names_refseq": "LOC101884921",
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        "protein_names_refseq": "lysophosphatidylcholine acyltransferase 1",
        "tax_id": 7955,
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        "go_molecular_function": "GO:0016746 acyltransferase activity",
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        "record_id": "A0AC58HIK4-1",
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        "protein_name": "Regulation of nuclear pre-mRNA domain-containing protein 2",
        "gene_name": "rprd2b",
        "organism": "Zebrafish",
        "refseq_name": "regulation of nuclear pre-mRNA domain-containing protein 2",
        "refseq_ac": "XP_073781778",
        "gene_names_uniprotkb": "rprd2b",
        "gene_names_refseq": "rprd2b",
        "protein_names_uniprotkb": "Regulation of nuclear pre-mRNA domain-containing protein 2",
        "protein_names_refseq": "regulation of nuclear pre-mRNA domain-containing protein 2",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 3,
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    {
        "uniprot_canonical_ac": "A0AC58HIN0-1",
        "uniprot_id": "A0AC58HIN0_DANRE",
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        "length": 1262,
        "protein_name": "Zinc finger protein 236",
        "gene_name": "LOC141378155",
        "organism": "Zebrafish",
        "refseq_name": "zinc finger protein 236",
        "refseq_ac": "XP_073781879",
        "gene_names_uniprotkb": "LOC141378155",
        "gene_names_refseq": "LOC141378155",
        "protein_names_uniprotkb": "Zinc finger protein 236",
        "protein_names_refseq": "zinc finger protein 236",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; May be involved in transcriptional regulation., [UniProtKB, UniProtKB]",
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        "protein_name": "Solute carrier family 2, facilitated glucose transporter member 5",
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        "protein_names_refseq": "solute carrier family 2, facilitated glucose transporter member 3 isoform X1",
        "tax_id": 7955,
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        "protein_name": "Hemicentin-1 isoform X1",
        "gene_name": "LOC108179508",
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        "gene_names_refseq": "LOC141378303",
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        "protein_names_refseq": "uncharacterized protein",
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        "length": 208,
        "protein_name": "Uncharacterized protein",
        "gene_name": "LOC137487961",
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        "uniprot_id": "A0AC58HL35_DANRE",
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        "length": 1359,
        "protein_name": "ATPase family AAA domain-containing protein 2",
        "gene_name": "atad2",
        "organism": "Zebrafish",
        "refseq_name": "ATPase family AAA domain-containing protein 2 isoform X1",
        "refseq_ac": "XP_073782714",
        "gene_names_uniprotkb": "atad2",
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        "protein_names_uniprotkb": "ATPase family AAA domain-containing protein 2",
        "protein_names_refseq": "ATPase family AAA domain-containing protein 2 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "length": 829,
        "protein_name": "Zinc fingers and homeoboxes protein 1",
        "gene_name": "zhx1",
        "organism": "Zebrafish",
        "refseq_name": "zinc fingers and homeoboxes protein 1",
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        "predicted_glycosites": 1,
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        "length": 1425,
        "protein_name": "Gypsy retrotransposon integrase-like protein 1",
        "gene_name": "LOC141378312",
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        "refseq_name": "uncharacterized protein",
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        "protein_names_uniprotkb": "Gypsy retrotransposon integrase-like protein 1; 3.1.26.4",
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        "length": 359,
        "protein_name": "Uncharacterized protein",
        "gene_name": "LOC141378314",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": "XP_073782822",
        "gene_names_uniprotkb": "LOC141378314",
        "gene_names_refseq": "LOC141378314",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "uncharacterized protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "secondary_ac_list": "A0AC58HLF3;A0AC58HLH9",
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    {
        "uniprot_canonical_ac": "A0AC58HLH5-1",
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        "length": 1234,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC141378313",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073782811",
        "gene_names_uniprotkb": "LOC141378313",
        "gene_names_refseq": "LOC141378313",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HLH5-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HLF9-1",
        "uniprot_id": "A0AC58HLF9_DANRE",
        "mass": 57934.0,
        "length": 505,
        "protein_name": "Dendritic cell-specific transmembrane protein",
        "gene_name": "dcstamp",
        "organism": "Zebrafish",
        "refseq_name": "dendritic cell-specific transmembrane protein",
        "refseq_ac": "XP_073782796",
        "gene_names_uniprotkb": "dcstamp",
        "gene_names_refseq": "dcstamp",
        "protein_names_uniprotkb": "Dendritic cell-specific transmembrane protein",
        "protein_names_refseq": "dendritic cell-specific transmembrane protein",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
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        "reported_n_glycosites_with_glycan": 0,
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        "reported_c_glycosites_with_glycan": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "glyco_site_count": 1,
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        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HLF9-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HLH0-1",
        "uniprot_id": "A0AC58HLH0_DANRE",
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        "length": 287,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC101886607",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073782833",
        "gene_names_uniprotkb": "LOC101886607",
        "gene_names_refseq": "LOC101886607",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "go_molecular_function": "",
        "go_cellular_component": "",
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        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HLH0-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HLG5-1",
        "uniprot_id": "A0AC58HLG5_DANRE",
        "mass": 32569.0,
        "length": 289,
        "protein_name": "1-phosphatidylinositol phosphodiesterase-like",
        "gene_name": "LOC100150005",
        "organism": "Zebrafish",
        "refseq_name": "1-phosphatidylinositol phosphodiesterase-like",
        "refseq_ac": "XP_073782832",
        "gene_names_uniprotkb": "LOC100150005",
        "gene_names_refseq": "LOC100150005",
        "protein_names_uniprotkb": "1-phosphatidylinositol phosphodiesterase-like",
        "protein_names_refseq": "1-phosphatidylinositol phosphodiesterase-like",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "go_cellular_component": "",
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        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HLG5-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HLH6-1",
        "uniprot_id": "A0AC58HLH6_DANRE",
        "mass": 40249.0,
        "length": 341,
        "protein_name": "Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1",
        "gene_name": "c1galt1b",
        "organism": "Zebrafish",
        "refseq_name": "glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 isoform X1",
        "refseq_ac": "XP_073782847",
        "gene_names_uniprotkb": "c1galt1b",
        "gene_names_refseq": "c1galt1b",
        "protein_names_uniprotkb": "Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; 2.4.1.122; Core 1 O-glycan T-synthase; Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1; Core 1 beta1,3-galactosyltransferase 1",
        "protein_names_refseq": "glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 isoform X1",
        "tax_id": 7955,
        "disease": "",
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        "publication_id_list": "",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins., [UniProtKB, UniProtKB, UniProtKB]",
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": "2.4.1.122",
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        "go_cellular_component": "",
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        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HLH6-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58HLK5-1",
        "uniprot_id": "A0AC58HLK5_DANRE",
        "mass": 35550.0,
        "length": 308,
        "protein_name": "Uncharacterized protein",
        "gene_name": "LOC141378331",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": "XP_073782869",
        "gene_names_uniprotkb": "LOC141378331",
        "gene_names_refseq": "LOC141378331",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
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        "biomarker_type": "",
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        "secondary_ac_list": "",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio                   :: 21% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "length": 560,
        "protein_name": "DNA polymerase epsilon subunit",
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        "refseq_name": "DNA polymerase epsilon subunit 2 isoform X1",
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        "protein_names_uniprotkb": "DNA polymerase epsilon subunit; DNA polymerase II subunit 2",
        "protein_names_refseq": "DNA polymerase epsilon subunit 2 isoform X1",
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        "refseq_ac": "XP_073783047",
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        "protein_names_refseq": "prospero homeobox protein 1a isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Potassium voltage-gated channel subfamily H member 1a isoform X1",
        "gene_name": "kcnh1a",
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        "refseq_name": "potassium voltage-gated channel subfamily H member 1a isoform X1",
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        "gene_names_refseq": "Eag1; Kv10.1; kcnh1a; kcnh1",
        "protein_names_uniprotkb": "Potassium voltage-gated channel subfamily H member 1a isoform X1",
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        "gene_name": "atxn3",
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        "ec_number_list": "3.4.19.12;3.6.4.6",
        "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006508 proteolysis;GO:0016579 protein deubiquitination;GO:0042461 photoreceptor cell development;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process",
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    },
    {
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        "uniprot_id": "A0AC58HQR7_DANRE",
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        "length": 1038,
        "protein_name": "Kinesin-like protein 6",
        "gene_name": "kif28",
        "organism": "Zebrafish",
        "refseq_name": "kinesin-like protein KIF28P isoform X1",
        "refseq_ac": "XP_073784313",
        "gene_names_uniprotkb": "kif28",
        "gene_names_refseq": "kif28",
        "protein_names_uniprotkb": "Kinesin-like protein 6",
        "protein_names_refseq": "kinesin-like protein KIF28P isoform X1",
        "tax_id": 7955,
        "disease": "autosomal dominant polycystic kidney disease (Disease Ontology:DOID:898)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Microtubule-dependent motor protein required for mitochondrion morphology and transport of mitochondria in neuronal cells., [UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0016887 ATP hydrolysis activity;GO:0003777 microtubule motor activity",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0031966 mitochondrial membrane;GO:0005871 kinesin complex",
        "go_biological_process": "GO:0048731 system development;GO:0047496 vesicle transport along microtubule",
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        "record_id": "A0AC58HQR7-1",
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    },
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        "uniprot_id": "A0AC58HQV3_DANRE",
        "mass": 281848.0,
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        "protein_name": "Ral GTPase-activating protein subunit alpha-1 isoform X1",
        "gene_name": "ralgapa1",
        "organism": "Zebrafish",
        "refseq_name": "ral GTPase-activating protein subunit alpha-1 isoform X1",
        "refseq_ac": "XP_073784320",
        "gene_names_uniprotkb": "ralgapa1",
        "gene_names_refseq": "ralgapa1",
        "protein_names_uniprotkb": "Ral GTPase-activating protein subunit alpha-1 isoform X1",
        "protein_names_refseq": "ral GTPase-activating protein subunit alpha-1 isoform X1",
        "tax_id": 7955,
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        "pathway": " (dre:556427)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "GO:0005096 GTPase activator activity",
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        "length": 689,
        "protein_name": "Sentrin-specific protease 6 isoform X1",
        "gene_name": "senp6b",
        "organism": "Zebrafish",
        "refseq_name": "sentrin-specific protease 6 isoform X1",
        "refseq_ac": "XP_073783897",
        "gene_names_uniprotkb": "senp6b",
        "gene_names_refseq": "senp6b",
        "protein_names_uniprotkb": "Sentrin-specific protease 6 isoform X1",
        "protein_names_refseq": "sentrin-specific protease 6 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0008234 cysteine-type peptidase activity;GO:0008233 peptidase activity",
        "go_cellular_component": "",
        "go_biological_process": "GO:0006508 proteolysis",
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        "hit_score": 0.1,
        "record_id": "A0AC58HPH5-1",
        "record_type": "protein"
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        "uniprot_canonical_ac": "A0AC58HN56-1",
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        "length": 568,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "zgc:154055",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073783423",
        "gene_names_uniprotkb": "zgc:154055; zgc:154055",
        "gene_names_refseq": "zgc:154055",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
        "disease": "centronuclear myopathy X-linked (Disease Ontology:DOID:0111225); Charcot-Marie-Tooth disease (Disease Ontology:DOID:10595); centronuclear myopathy (Disease Ontology:DOID:14717)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "record_type": "protein"
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        "uniprot_id": "A0AC58HQ89_DANRE",
        "mass": 53493.0,
        "length": 475,
        "protein_name": "Zinc finger and BTB domain-containing protein 18",
        "gene_name": "zbtb42",
        "organism": "Zebrafish",
        "refseq_name": "zinc finger and BTB domain-containing protein 42 isoform X1",
        "refseq_ac": "XP_073784133",
        "gene_names_uniprotkb": "zbtb42",
        "gene_names_refseq": "zbtb42",
        "protein_names_uniprotkb": "Zinc finger and BTB domain-containing protein 18; Zinc finger protein 238",
        "protein_names_refseq": "zinc finger and BTB domain-containing protein 42 isoform X1",
        "tax_id": 7955,
        "disease": "distal arthrogryposis (Disease Ontology:DOID:0050646); lethal congenital contracture syndrome (Disease Ontology:DOID:0060558)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding",
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        "uniprot_id": "A0AC58HND9_DANRE",
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        "length": 515,
        "protein_name": "Si:dkey-190l8.2 isoform X1",
        "gene_name": "si:dkey-190l8.2",
        "organism": "Zebrafish",
        "refseq_name": "si:dkey-190l8.2 isoform X1",
        "refseq_ac": "XP_073783496",
        "gene_names_uniprotkb": "si:dkey-190l8.2",
        "gene_names_refseq": "si:dkey-190l8.2",
        "protein_names_uniprotkb": "Si:dkey-190l8.2 isoform X1",
        "protein_names_refseq": "si:dkey-190l8.2 isoform X1",
        "tax_id": 7955,
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        "pathway": " (dre:566640);  (R-DRE-196807)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "secondary_ac_list": "A0AC58HNE2",
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        "go_molecular_function": "GO:0022857 transmembrane transporter activity",
        "go_cellular_component": "GO:0016020 membrane",
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        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC110438072",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073783343",
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        "protein_name": "Disheveled-associated activator of morphogenesis 1 isoform X1",
        "gene_name": "daam1a",
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        "refseq_name": "disheveled-associated activator of morphogenesis 1 isoform X1",
        "refseq_ac": "XP_073784340",
        "gene_names_uniprotkb": "daam1a",
        "gene_names_refseq": "daam1a",
        "protein_names_uniprotkb": "Disheveled-associated activator of morphogenesis 1 isoform X1",
        "protein_names_refseq": "disheveled-associated activator of morphogenesis 1 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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    {
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        "mass": 50950.0,
        "length": 458,
        "protein_name": "Steroid hormone receptor ERR2 isoform X1",
        "gene_name": "esrrb",
        "organism": "Zebrafish",
        "refseq_name": "steroid hormone receptor ERR2 isoform X1",
        "refseq_ac": "XP_073783268",
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        "gene_names_refseq": "errbeta; errb; esrrb",
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        "protein_names_refseq": "steroid hormone receptor ERR2 isoform X1",
        "tax_id": 7955,
        "disease": "autosomal recessive nonsyndromic deafness 35 (Disease Ontology:DOID:0110493); dilated cardiomyopathy (Disease Ontology:DOID:12930); azoospermia (Disease Ontology:DOID:14227); cancer (Disease Ontology:DOID:162)",
        "pathway": " (dre:407693)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "GO:0034056 estrogen response element binding;GO:0008270 zinc ion binding;GO:0003707 nuclear steroid receptor activity;GO:0042562 hormone binding;GO:0005496 steroid binding",
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        "gene_name": "daam2",
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        "refseq_ac": "XP_073783764",
        "gene_names_uniprotkb": "daam2",
        "gene_names_refseq": "daam2",
        "protein_names_uniprotkb": "Disheveled-associated activator of morphogenesis 2 isoform X1",
        "protein_names_refseq": "disheveled-associated activator of morphogenesis 2 isoform X1",
        "tax_id": 7955,
        "disease": "nephrotic syndrome type 24 (Disease Ontology:DOID:0061194)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "uniprot_canonical_ac": "A0AC58HPI9-1",
        "uniprot_id": "A0AC58HPI9_DANRE",
        "mass": 20189.0,
        "length": 176,
        "protein_name": "Placenta growth factor isoform X1",
        "gene_name": "pgfb",
        "organism": "Zebrafish",
        "refseq_name": "placenta growth factor isoform X1",
        "refseq_ac": "XP_073783862",
        "gene_names_uniprotkb": "pgfb",
        "gene_names_refseq": "pgfb",
        "protein_names_uniprotkb": "Placenta growth factor isoform X1",
        "protein_names_refseq": "placenta growth factor isoform X1",
        "tax_id": 7955,
        "disease": "pre-eclampsia (Disease Ontology:DOID:10591); hypertension (Disease Ontology:DOID:10763); sickle cell anemia (Disease Ontology:DOID:10923); pyelonephritis (Disease Ontology:DOID:11400); limited scleroderma (Disease Ontology:DOID:1577); breast cancer (Disease Ontology:DOID:1612); pancreatic endocrine carcinoma (Disease Ontology:DOID:1798); epilepsy (Disease Ontology:DOID:1826); brain ischemia (Disease Ontology:DOID:2316); asthma (Disease Ontology:DOID:2841); glioblastoma (Disease Ontology:DOID:3068); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); temporal lobe epilepsy (Disease Ontology:DOID:3328); carotid artery disease (Disease Ontology:DOID:3407); renal cell carcinoma (Disease Ontology:DOID:4450); lymphedema (Disease Ontology:DOID:4977); liver cirrhosis (Disease Ontology:DOID:5082); myocardial infarction (Disease Ontology:DOID:5844); pulmonary hypertension (Disease Ontology:DOID:6432); ankylosing spondylitis (Disease Ontology:DOID:7147); rheumatoid arthritis (Disease Ontology:DOID:7148); Crohn's disease (Disease Ontology:DOID:8778); systemic lupus erythematosus (Disease Ontology:DOID:9074); diabetic neuropathy (Disease Ontology:DOID:9743); obesity (Disease Ontology:DOID:9970)",
        "pathway": " (dre:557468)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0008083 growth factor activity",
        "go_cellular_component": "GO:0005576 extracellular region;GO:0016020 membrane",
        "go_biological_process": "GO:0001525 angiogenesis;GO:0030154 cell differentiation;GO:0051781 positive regulation of cell division;GO:0048513 animal organ development;GO:0051239 regulation of multicellular organismal process",
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    {
        "uniprot_canonical_ac": "A0AC58HMF3-1",
        "uniprot_id": "A0AC58HMF3_DANRE",
        "mass": 97652.0,
        "length": 852,
        "protein_name": "Cell division cycle 5-like protein",
        "gene_name": "cdc5l",
        "organism": "Zebrafish",
        "refseq_name": "cell division cycle 5-like protein isoform X1",
        "refseq_ac": "XP_073783170",
        "gene_names_uniprotkb": "cdc5l; zgc:55853",
        "gene_names_refseq": "cdc5l; zgc:55853",
        "protein_names_uniprotkb": "Cell division cycle 5-like protein",
        "protein_names_refseq": "cell division cycle 5-like protein isoform X1",
        "tax_id": 7955,
        "disease": "osteosarcoma (Disease Ontology:DOID:3347); esophagus adenocarcinoma (Disease Ontology:DOID:4914)",
        "pathway": " (dre:394059);  (R-DRE-72163)",
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        "publication_id_list": "26469318;27189481;28803829;28972010;33785593",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Plays a role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR). As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0019904 protein domain specific binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific",
        "go_cellular_component": "GO:0016607 nuclear speck;GO:0005681 spliceosomal complex;GO:0000974 Prp19 complex",
        "go_biological_process": "GO:0006281 DNA repair;GO:0006357 regulation of transcription by RNA polymerase II;GO:0000398 mRNA splicing, via spliceosome",
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        "protein_name": "Brain-enriched guanylate kinase-associated protein isoform X1",
        "gene_name": "begain",
        "organism": "Zebrafish",
        "refseq_name": "brain-enriched guanylate kinase-associated protein isoform X1",
        "refseq_ac": "XP_073784059",
        "gene_names_uniprotkb": "begain",
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        "protein_names_uniprotkb": "Brain-enriched guanylate kinase-associated protein isoform X1",
        "protein_names_refseq": "brain-enriched guanylate kinase-associated protein isoform X1",
        "tax_id": 7955,
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        "pathway": " (dre:101883656)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0016301 kinase activity",
        "go_cellular_component": "GO:0016020 membrane;GO:0045202 synapse;GO:0098794 postsynapse",
        "go_biological_process": "GO:0098817 evoked excitatory postsynaptic potential",
        "synthesized_glycan_count": 0,
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        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HQF3-1",
        "uniprot_id": "A0AC58HQF3_DANRE",
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        "length": 1344,
        "protein_name": "Uncharacterized protein si:ch211-14a17.10 isoform X1",
        "gene_name": "si:ch211-14a17.10",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:ch211-14a17.10 isoform X1",
        "refseq_ac": "XP_073784209",
        "gene_names_uniprotkb": "si:ch211-14a17.10",
        "gene_names_refseq": "si:ch211-14a17.10",
        "protein_names_uniprotkb": "Uncharacterized protein si:ch211-14a17.10 isoform X1",
        "protein_names_refseq": "uncharacterized protein si:ch211-14a17.10 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "GO:0061630 ubiquitin protein ligase activity",
        "go_cellular_component": "GO:0005737 cytoplasm",
        "go_biological_process": "GO:0045087 innate immune response",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HQF3-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HNG5-1",
        "uniprot_id": "A0AC58HNG5_DANRE",
        "mass": 48340.0,
        "length": 447,
        "protein_name": "Saccharopine dehydrogenase-like oxidoreductase",
        "gene_name": "sccpdha.2",
        "organism": "Zebrafish",
        "refseq_name": "saccharopine dehydrogenase a, tandem duplicate 2 isoform X1",
        "refseq_ac": "XP_073783520",
        "gene_names_uniprotkb": "sccpdha.2; zgc:174379",
        "gene_names_refseq": "sccpdha.2; zgc:174379",
        "protein_names_uniprotkb": "Saccharopine dehydrogenase-like oxidoreductase",
        "protein_names_refseq": "saccharopine dehydrogenase a, tandem duplicate 2 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:569379)",
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        "publication_id_list": "32722765",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "",
        "go_cellular_component": "GO:0005811 lipid droplet;GO:0016020 membrane",
        "go_biological_process": "GO:0009247 glycolipid biosynthetic process",
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    },
    {
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        "length": 486,
        "protein_name": "F-box only protein 33 isoform X1",
        "gene_name": "fbxo33",
        "organism": "Zebrafish",
        "refseq_name": "F-box only protein 33 isoform X1",
        "refseq_ac": "XP_073784334",
        "gene_names_uniprotkb": "fbxo33",
        "gene_names_refseq": "fbxo33",
        "protein_names_uniprotkb": "F-box only protein 33 isoform X1",
        "protein_names_refseq": "F-box only protein 33 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_biological_process": "GO:0031398 positive regulation of protein ubiquitination",
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        "record_type": "protein"
    },
    {
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        "uniprot_id": "A0AC58HQP6_DANRE",
        "mass": 58905.0,
        "length": 510,
        "protein_name": "non-specific serine/threonine protein kinase",
        "gene_name": "LOC110438059",
        "organism": "Zebrafish",
        "refseq_name": "serine/threonine-protein kinase pim-2-like isoform X1",
        "refseq_ac": "XP_073784318",
        "gene_names_uniprotkb": "LOC110438059",
        "gene_names_refseq": "LOC110438059",
        "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1",
        "protein_names_refseq": "serine/threonine-protein kinase pim-2-like isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:110438059)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "glyco_site_count": 0,
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        "secondary_ac_list": "",
        "ec_number_list": "2.7.11.1;2.7.11.13;2.7.11.25;2.7.10.1;2.7.11.22;2.7.11.21;2.7.11.17;2.7.12.1;2.7.12.2;2.7.11.24;2.7.10.2;2.7.11.23;2.7.1.150;2.7.11.12;2.7.11.39;2.7.11.11;2.7.1.153;2.7.1.137;2.7.1.154;2.7.11.26;2.7.11.31",
        "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HQP6-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HN43-1",
        "uniprot_id": "A0AC58HN43_DANRE",
        "mass": 90337.0,
        "length": 794,
        "protein_name": "Kinesin-like protein",
        "gene_name": "kif6",
        "organism": "Zebrafish",
        "refseq_name": "kinesin-like protein KIF6 isoform X1",
        "refseq_ac": "XP_073783383",
        "gene_names_uniprotkb": "kif6; zgc:152746",
        "gene_names_refseq": "kif6; zgc:152746",
        "protein_names_uniprotkb": "Kinesin-like protein",
        "protein_names_refseq": "kinesin-like protein KIF6 isoform X1",
        "tax_id": 7955,
        "disease": "stroke (Disease Ontology:DOID:0051061); idiopathic scoliosis (Disease Ontology:DOID:0060250); aortic dissection (Disease Ontology:DOID:0080685); hypertension (Disease Ontology:DOID:10763); coronary artery disease (Disease Ontology:DOID:3393); myocardial infarction (Disease Ontology:DOID:5844); type 2 diabetes mellitus (Disease Ontology:DOID:9352); acute myocardial infarction (Disease Ontology:DOID:9408)",
        "pathway": " (dre:553436)",
        "pathway_count": 1,
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        "publication_id_list": "25139857;25283277;26469318;27189481;28174019;30475797;33290818",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0003777 microtubule motor activity",
        "go_cellular_component": "GO:0005874 microtubule;GO:0097546 ciliary base",
        "go_biological_process": "GO:0021510 spinal cord development;GO:0007018 microtubule-based movement",
        "synthesized_glycan_count": 0,
        "hit_score": 0.8,
        "record_id": "A0AC58HN43-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HME9-1",
        "uniprot_id": "A0AC58HME9_DANRE",
        "mass": 58234.0,
        "length": 515,
        "protein_name": "Tryptophan--tRNA ligase, cytoplasmic",
        "gene_name": "wars1",
        "organism": "Zebrafish",
        "refseq_name": "tryptophan--tRNA ligase, cytoplasmic isoform 1",
        "refseq_ac": "NP_001430134",
        "gene_names_uniprotkb": "wars1; TrpRS; wars; zgc:73274",
        "gene_names_refseq": "TrpRS; wars1; wars; zgc:73274",
        "protein_names_uniprotkb": "Tryptophan--tRNA ligase, cytoplasmic; 6.1.1.2; Tryptophanyl-tRNA synthetase",
        "protein_names_refseq": "tryptophan--tRNA ligase, cytoplasmic isoform 1; tryptophan--tRNA ligase, cytoplasmic",
        "tax_id": 7955,
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        "pathway_count": 0,
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        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588730.14961307.1, SRR32588722.10997115.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505373, SAMEA3505377 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000017.1. On Sep 8, 2025 this sequence version replaced XP_073783169.1. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
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        "go_molecular_function": "GO:0016874 ligase activity",
        "go_cellular_component": "",
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        "record_id": "A0AC58HME9-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HMG0-1",
        "uniprot_id": "A0AC58HMG0_DANRE",
        "mass": 179225.0,
        "length": 1547,
        "protein_name": "RNA helicase aquarius",
        "gene_name": "aqr",
        "organism": "Zebrafish",
        "refseq_name": "",
        "refseq_ac": "",
        "gene_names_uniprotkb": "aqr; zgc:63611",
        "gene_names_refseq": "",
        "protein_names_uniprotkb": "RNA helicase aquarius; 3.6.4.13; Intron-binding protein of 160 kDa",
        "protein_names_refseq": "",
        "tax_id": 7955,
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        "function": "Involved in pre-mRNA splicing as component of the spliceosome. Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. Has ATP-dependent RNA helicase activity and can unwind double-stranded RNA molecules with a 3' overhang (in vitro)., [UniProtKB, UniProtKB, UniProtKB]",
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        "predicted_n_glycosites": 0,
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        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
        "reported_glycation": 0,
        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
        "disease_count": 0,
        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": "2.3.2.-;2.3.2.27;3.6.4.-;4.2.99.18;5.6.2.4;5.6.2.3;3.6.4.12;3.6.4.13;2.7.4.3;7.6.2.2;5.6.1.6;7.6.2.3;3.6.1.5;3.6.4.6;3.6.1.15;3.6.4.10;5.6.2.-;2.7.7.7;2.7.7.49;5.6.2.5;3.6.5.-;3.6.1.-",
        "go_molecular_function": "GO:0004386 helicase activity",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HMG0-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HN76-1",
        "uniprot_id": "A0AC58HN76_DANRE",
        "mass": 79118.0,
        "length": 718,
        "protein_name": "non-specific serine/threonine protein kinase",
        "gene_name": "LOC137487498",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": "XP_073783441",
        "gene_names_uniprotkb": "LOC137487498",
        "gene_names_refseq": "LOC137487498",
        "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1",
        "protein_names_refseq": "uncharacterized protein",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
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        "mined_glycosites": 0,
        "mined_n_glycosites": 0,
        "mined_o_glycosites": 0,
        "mined_c_glycosites": 0,
        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "total_reported_c_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "reported_snv": 0,
        "reported_interactions": 0,
        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "secondary_ac_list": "",
        "ec_number_list": "2.7.11.1;2.7.11.13;2.7.11.25;2.7.10.1;2.7.11.22;2.7.11.21;2.7.11.17;2.7.12.1;2.7.12.2;2.7.11.24;2.7.10.2;2.7.11.23;2.7.1.150;2.7.11.12;2.7.11.39;2.7.11.11;2.7.1.153;2.7.1.137;2.7.1.154;2.7.11.26;2.7.11.31",
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HN76-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HNP3-1",
        "uniprot_id": "A0AC58HNP3_DANRE",
        "mass": 117150.0,
        "length": 1041,
        "protein_name": "Ribosome quality control complex subunit NEMF",
        "gene_name": "zgc:153813",
        "organism": "Zebrafish",
        "refseq_name": "ribosome quality control complex subunit NEMF",
        "refseq_ac": "NP_001428600",
        "gene_names_uniprotkb": "zgc:153813",
        "gene_names_refseq": "nemf; zgc:153813",
        "protein_names_uniprotkb": "Ribosome quality control complex subunit NEMF; Nuclear export mediator factor",
        "protein_names_refseq": "nuclear export mediator factor NEMF; ribosome quality control complex subunit NEMF",
        "tax_id": 7955,
        "disease": "",
        "pathway": "",
        "pathway_count": 0,
        "publication_count": 1,
        "publication_id_list": "12477932",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR26395015.1154944.1, SRR26395062.761230.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000017.1. On Jun 25, 2025 this sequence version replaced XP_073783634.1., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
        "predicted_c_glycosites": 0,
        "predicted_s_glycosites": 0,
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        "mined_s_glycosites": 0,
        "reported_n_glycosites": 0,
        "reported_o_glycosites": 0,
        "reported_c_glycosites": 0,
        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "go_molecular_function": "",
        "go_cellular_component": "",
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        "synthesized_glycan_count": 0,
        "hit_score": 0.2,
        "record_id": "A0AC58HNP3-1",
        "record_type": "protein"
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        "uniprot_canonical_ac": "A0AC58HNR5-1",
        "uniprot_id": "A0AC58HNR5_DANRE",
        "mass": 58511.0,
        "length": 520,
        "protein_name": "Tetratricopeptide repeat protein 8 isoform X1",
        "gene_name": "ttc8",
        "organism": "Zebrafish",
        "refseq_name": "tetratricopeptide repeat protein 8 isoform X1",
        "refseq_ac": "XP_073783592",
        "gene_names_uniprotkb": "ttc8; bbs8; fk26c02; wu:fk26c02; zgc:136718",
        "gene_names_refseq": "bbs8; fk26c02; ttc8; wu:fk26c02; zgc:136718",
        "protein_names_uniprotkb": "Tetratricopeptide repeat protein 8 isoform X1",
        "protein_names_refseq": "tetratricopeptide repeat protein 8 isoform X1",
        "tax_id": 7955,
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        "pathway_count": 0,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 1,
        "predicted_c_glycosites": 0,
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        "mined_n_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
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        "reported_c_glycosites_with_glycan": 0,
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        "total_reported_n_glycosites": 0,
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        "missing_score": 10000,
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        "go_cellular_component": "",
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        "hit_score": 0.1,
        "record_id": "A0AC58HNR5-1",
        "record_type": "protein"
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        "uniprot_canonical_ac": "A0AC58HP35-1",
        "uniprot_id": "A0AC58HP35_DANRE",
        "mass": 94071.0,
        "length": 825,
        "protein_name": "Phospholipase DDHD1 isoform X1",
        "gene_name": "ddhd1a",
        "organism": "Zebrafish",
        "refseq_name": "phospholipase DDHD1 isoform X1",
        "refseq_ac": "XP_073783768",
        "gene_names_uniprotkb": "ddhd1a",
        "gene_names_refseq": "ddhd1a",
        "protein_names_uniprotkb": "Phospholipase DDHD1 isoform X1",
        "protein_names_refseq": "phospholipase DDHD1 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "A0AC58HP39;A0AC58HP45;A0AC58HP49",
        "ec_number_list": "",
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        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HP35-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58HP85-1",
        "uniprot_id": "A0AC58HP85_DANRE",
        "mass": 123299.0,
        "length": 1108,
        "protein_name": "Myelin transcription factor 1-like protein isoform X1",
        "gene_name": "myt1lb",
        "organism": "Zebrafish",
        "refseq_name": "myelin transcription factor 1-like protein isoform X1",
        "refseq_ac": "XP_073783757",
        "gene_names_uniprotkb": "myt1lb",
        "gene_names_refseq": "myt1lb",
        "protein_names_uniprotkb": "Myelin transcription factor 1-like protein isoform X1",
        "protein_names_refseq": "myelin transcription factor 1-like protein isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 3,
        "predicted_n_glycosites": 0,
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        "missing_score": 10000,
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        "go_molecular_function": "",
        "go_cellular_component": "",
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        "record_id": "A0AC58HP85-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58HP43-1",
        "uniprot_id": "A0AC58HP43_DANRE",
        "mass": 95887.0,
        "length": 843,
        "protein_name": "Coiled-coil domain-containing protein 177",
        "gene_name": "ccdc177",
        "organism": "Zebrafish",
        "refseq_name": "coiled-coil domain-containing protein 177",
        "refseq_ac": "XP_073783767",
        "gene_names_uniprotkb": "ccdc177",
        "gene_names_refseq": "ccdc177",
        "protein_names_uniprotkb": "Coiled-coil domain-containing protein 177",
        "protein_names_refseq": "coiled-coil domain-containing protein 177",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
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        "go_cellular_component": "",
        "go_biological_process": "",
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        "record_id": "A0AC58HP43-1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Serine/threonine protein phosphatase 2A regulatory subunit",
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        "gene_names_refseq": "ppp2r5ca",
        "protein_names_uniprotkb": "Serine/threonine protein phosphatase 2A regulatory subunit",
        "protein_names_refseq": "serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HSV4-1",
        "uniprot_id": "A0AC58HSV4_DANRE",
        "mass": 39334.0,
        "length": 374,
        "protein_name": "Ubiquitin-like protein 7b isoform X1",
        "gene_name": "ubl7b",
        "organism": "Zebrafish",
        "refseq_name": "ubiquitin-like protein 7b isoform X1",
        "refseq_ac": "XP_073785040",
        "gene_names_uniprotkb": "ubl7b; ubl7; zgc:64009",
        "gene_names_refseq": "ubl7b; ubl7; zgc:64009",
        "protein_names_uniprotkb": "Ubiquitin-like protein 7b isoform X1",
        "protein_names_refseq": "ubiquitin-like protein 7b isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:393331)",
        "pathway_count": 1,
        "publication_count": 3,
        "publication_id_list": "26469318;27189481;34208498",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Interferon-stimulated protein that positively regulates RNA virus-triggered innate immune signaling. Mechanistically, promotes 'Lys-27'-linked polyubiquitination of MAVS through TRIM21 leading to enhanced the IFN signaling pathway., [UniProtKB, UniProtKB]",
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "A0AC58HSZ0",
        "ec_number_list": "",
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "GO:0045087 innate immune response",
        "synthesized_glycan_count": 0,
        "hit_score": 0.4,
        "record_id": "A0AC58HSV4-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HRD2-1",
        "uniprot_id": "A0AC58HRD2_DANRE",
        "mass": 36707.0,
        "length": 335,
        "protein_name": "Uncharacterized protein si:ch211-248a14.8 isoform X1",
        "gene_name": "si:ch211-248a14.8",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:ch211-248a14.8 isoform X1",
        "refseq_ac": "XP_073784551",
        "gene_names_uniprotkb": "si:ch211-248a14.8",
        "gene_names_refseq": "si:ch211-248a14.8",
        "protein_names_uniprotkb": "Uncharacterized protein si:ch211-248a14.8 isoform X1",
        "protein_names_refseq": "uncharacterized protein si:ch211-248a14.8 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100001321)",
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
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        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HRD2-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HT36-1",
        "uniprot_id": "A0AC58HT36_DANRE",
        "mass": 51231.0,
        "length": 439,
        "protein_name": "Differentially expressed in FDCP 8 homolog isoform X1",
        "gene_name": "def8",
        "organism": "Zebrafish",
        "refseq_name": "differentially expressed in FDCP 8 homolog isoform X1",
        "refseq_ac": "XP_073785148",
        "gene_names_uniprotkb": "def8; zgc:101815",
        "gene_names_refseq": "def8; zgc:101815",
        "protein_names_uniprotkb": "Differentially expressed in FDCP 8 homolog isoform X1",
        "protein_names_refseq": "differentially expressed in FDCP 8 homolog isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:492523)",
        "pathway_count": 1,
        "publication_count": 1,
        "publication_id_list": "26469318",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts. Involved in bone resorption., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "reported_s_glycosites": 0,
        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
        "reported_s_glycosites_with_glycan": 0,
        "total_reported_n_glycosites": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
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        "reported_snv": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "GO:0008270 zinc ion binding",
        "go_cellular_component": "",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.2,
        "record_id": "A0AC58HT36-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HT46-1",
        "uniprot_id": "A0AC58HT46_DANRE",
        "mass": 39864.0,
        "length": 364,
        "protein_name": "Homeobox protein aristaless-like 4",
        "gene_name": "alx4b",
        "organism": "Zebrafish",
        "refseq_name": "homeobox protein aristaless-like 4b",
        "refseq_ac": "NP_001297007",
        "gene_names_uniprotkb": "alx4b; im:7142878; si:ch73-220n21.1; zgc:162606",
        "gene_names_refseq": "alx4b; im:7142878; si:ch73-220n21.1; zgc:162606",
        "protein_names_uniprotkb": "Homeobox protein aristaless-like 4",
        "protein_names_refseq": "aristaless-like homeobox 4b; homeobox protein aristaless-like 4b",
        "tax_id": 7955,
        "disease": "parietal foramina (Disease Ontology:DOID:0060285); frontonasal dysplasia 2 (Disease Ontology:DOID:0081046); lung cancer (Disease Ontology:DOID:1324); craniosynostosis (Disease Ontology:DOID:2340); gastric adenocarcinoma (Disease Ontology:DOID:3717); lung adenocarcinoma (Disease Ontology:DOID:3910); bronchiolo-alveolar adenocarcinoma (Disease Ontology:DOID:4926); hepatocellular carcinoma (Disease Ontology:DOID:684); colorectal cancer (Disease Ontology:DOID:9256)",
        "pathway": " (dre:497424)",
        "pathway_count": 1,
        "publication_count": 9,
        "publication_id_list": "21740507;23059813;24662046;25630924;30561090;31140974;32914578;33741714;34607603",
        "class_list": "",
        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588725.27389305.1, SRR32588728.7312989.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505376 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000018.1. On or before Jun 10, 2025 this sequence version replaced XP_073785164.1, NP_001297007.1. Sequence Note:. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]",
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        "predicted_n_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "",
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        "go_molecular_function": "",
        "go_cellular_component": "GO:0005634 nucleus",
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        "synthesized_glycan_count": 0,
        "hit_score": 1.0,
        "record_id": "A0AC58HT46-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HS97-1",
        "uniprot_id": "A0AC58HS97_DANRE",
        "mass": 67267.0,
        "length": 584,
        "protein_name": "Tripartite motif containing 35-30 isoform X1",
        "gene_name": "trim35-30",
        "organism": "Zebrafish",
        "refseq_name": "tripartite motif containing 35-30 isoform X1",
        "refseq_ac": "XP_073784857",
        "gene_names_uniprotkb": "trim35-30; si:dkeyp-1h4.3",
        "gene_names_refseq": "si:dkeyp-1h4.3; trim35-30",
        "protein_names_uniprotkb": "Tripartite motif containing 35-30 isoform X1",
        "protein_names_refseq": "tripartite motif containing 35-30 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100034496)",
        "pathway_count": 1,
        "publication_count": 1,
        "publication_id_list": "21789205",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "mined_s_glycosites": 0,
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        "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity",
        "go_cellular_component": "GO:0005737 cytoplasm",
        "go_biological_process": "GO:0045087 innate immune response",
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        "hit_score": 0.2,
        "record_id": "A0AC58HS97-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HR31-1",
        "uniprot_id": "A0AC58HR31_DANRE",
        "mass": 87179.0,
        "length": 776,
        "protein_name": "Transcription regulator protein BACH2 isoform X1",
        "gene_name": "bach2a",
        "organism": "Zebrafish",
        "refseq_name": "transcription regulator protein BACH2 isoform X1",
        "refseq_ac": "XP_073784434",
        "gene_names_uniprotkb": "bach2a",
        "gene_names_refseq": "bach2a",
        "protein_names_uniprotkb": "Transcription regulator protein BACH2 isoform X1",
        "protein_names_refseq": "transcription regulator protein BACH2 isoform X1",
        "tax_id": 7955,
        "disease": "immunodeficiency 60 (Disease Ontology:DOID:0111954)",
        "pathway": " (R-DRE-9707616);  (R-DRE-9708530)",
        "pathway_count": 2,
        "publication_count": 0,
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HR31-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HTE2-1",
        "uniprot_id": "A0AC58HTE2_DANRE",
        "mass": 99621.0,
        "length": 873,
        "protein_name": "FYVE, RhoGEF and PH domain-containing protein 4a isoform X1",
        "gene_name": "fgd4a",
        "organism": "Zebrafish",
        "refseq_name": "FYVE, RhoGEF and PH domain-containing protein 4a isoform X1",
        "refseq_ac": "XP_073785241",
        "gene_names_uniprotkb": "fgd4a; fgd4; si:ch211-194i18.1; si:dkey-57m7.1",
        "gene_names_refseq": "fgd4a; fgd4; si:ch211-194i18.1; si:dkey-57m7.1",
        "protein_names_uniprotkb": "FYVE, RhoGEF and PH domain-containing protein 4a isoform X1",
        "protein_names_refseq": "FYVE, RhoGEF and PH domain-containing protein 4a isoform X1",
        "tax_id": 7955,
        "disease": "Charcot-Marie-Tooth disease type 4H (Disease Ontology:DOID:0110192); Charcot-Marie-Tooth disease (Disease Ontology:DOID:10595); X-linked Aarskog syndrome (Disease Ontology:DOID:6683)",
        "pathway": " (dre:556216)",
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        "protein_name": "Phospholipase B1, membrane-associated",
        "gene_name": "plb1",
        "organism": "Zebrafish",
        "refseq_name": "phospholipase B1, membrane-associated isoform X1",
        "refseq_ac": "XP_073784669",
        "gene_names_uniprotkb": "plb1",
        "gene_names_refseq": "plb1",
        "protein_names_uniprotkb": "Phospholipase B1, membrane-associated; 3.1.1.3; 3.1.1.4; 3.1.1.5; Lysophospholipase; Phospholipase A2; Phospholipase B/lipase; Triacylglycerol lipase",
        "protein_names_refseq": "phospholipase B1, membrane-associated isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:560649)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Calcium-independent membrane-associated phospholipase that catalyzes complete diacylation of phospholipids by hydrolyzing both sn-1 and sn-2 fatty acyl chains attached to the glycerol backbone (phospholipase B activity). Has dual phospholipase and lysophospholipase activities toward diacylphospholipids. Preferentially cleaves sn-2 ester bonds over sn-1 bonds. Acts as a lipase toward glycerolipid substrates. Hydrolyzes fatty acyl chains of diacylglycerols with preference for the sn-2 position and of triacylglycerols with not positional selectivity. May also hydrolyze long chain retinyl esters such as retinyl palmitate. May contribute to digestion of dietary phospholipids, glycerolipids and retinoids, facilitating lipid absorption at the brush border., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "predicted_s_glycosites": 0,
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        "reported_c_glycosites": 0,
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        "reported_n_glycosites_with_glycan": 0,
        "reported_o_glycosites_with_glycan": 0,
        "reported_c_glycosites_with_glycan": 0,
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        "reported_fully_resolved_glycans": 0,
        "reported_phosphosites": 0,
        "reported_mutagensis": 0,
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        "missing_score": 10000,
        "biomarker_type": "",
        "glycan_count": 0,
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        "glyco_site_count": 0,
        "binding_glycan_count": 0,
        "secondary_ac_list": "",
        "ec_number_list": "3.1.1.34;3.1.1.32;3.1.1.4;2.3.1.-;3.1.1.-;3.1.1.5;3.1.1.23;3.1.1.79;3.1.1.3;3.1.1.116;3.1.1.6;3.1.-.-",
        "go_molecular_function": "GO:0004622 phosphatidylcholine lysophospholipase activity;GO:0004623 phospholipase A2 activity;GO:0004806 triacylglycerol lipase activity;GO:0050253 retinyl-palmitate esterase activity",
        "go_cellular_component": "GO:0031526 brush border membrane",
        "go_biological_process": "GO:0006644 phospholipid metabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HRP9-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HSB5-1",
        "uniprot_id": "A0AC58HSB5_DANRE",
        "mass": 161463.0,
        "length": 1433,
        "protein_name": "Tyrosine-protein kinase receptor",
        "gene_name": "igf1ra",
        "organism": "Zebrafish",
        "refseq_name": "insulin-like growth factor 1a receptor isoform X1",
        "refseq_ac": "XP_073784886",
        "gene_names_uniprotkb": "igf1ra; IGF-IRa; sb:eu1090; wu:fi20b10",
        "gene_names_refseq": "IGF-IRa; igf1ra; sb:eu1090; wu:fi20b10",
        "protein_names_uniprotkb": "Tyrosine-protein kinase receptor; 2.7.10.1",
        "protein_names_refseq": "insulin-like growth factor 1a receptor isoform X1",
        "tax_id": 7955,
        "disease": "fetal alcohol spectrum disorder (Disease Ontology:DOID:0050696); cardiomyopathy (Disease Ontology:DOID:0050700); alcohol dependence (Disease Ontology:DOID:0050741); Zollinger-Ellison syndrome (Disease Ontology:DOID:0050782); stroke (Disease Ontology:DOID:0051061); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); prostate cancer (Disease Ontology:DOID:10283); prostate carcinoma (Disease Ontology:DOID:10286); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); Kuhnt-Junius degeneration (Disease Ontology:DOID:10873); gastroschisis (Disease Ontology:DOID:11044); prostatic hypertrophy (Disease Ontology:DOID:11132); cryptorchidism (Disease Ontology:DOID:11383); osteoporosis (Disease Ontology:DOID:11476); portal vein thrombosis (Disease Ontology:DOID:11695); gestational diabetes (Disease Ontology:DOID:11714); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); Lewy body dementia (Disease Ontology:DOID:12217); Graves' disease (Disease Ontology:DOID:12361); dementia (Disease Ontology:DOID:1307); alcoholic neuropathy (Disease Ontology:DOID:14183); Parkinson's disease (Disease Ontology:DOID:14330); breast cancer (Disease Ontology:DOID:1612); cancer (Disease Ontology:DOID:162); pancreatic cancer (Disease Ontology:DOID:1793); nephroblastoma (Disease Ontology:DOID:2154); prostate adenocarcinoma (Disease Ontology:DOID:2526); IgA glomerulonephritis (Disease Ontology:DOID:2986); acute kidney failure (Disease Ontology:DOID:3021); high grade glioma (Disease Ontology:DOID:3070); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); pancreatic ductal carcinoma (Disease Ontology:DOID:3587); toxic encephalopathy (Disease Ontology:DOID:3602); glucose metabolism disease (Disease Ontology:DOID:4194); coronary stenosis (Disease Ontology:DOID:4248); renal cell carcinoma (Disease Ontology:DOID:4450); clear cell renal cell carcinoma (Disease Ontology:DOID:4467); liver cirrhosis (Disease Ontology:DOID:5082); sleep disorder (Disease Ontology:DOID:535); gastrinoma (Disease Ontology:DOID:5577); myocardial infarction (Disease Ontology:DOID:5844); hepatocellular carcinoma (Disease Ontology:DOID:684); neuroblastoma (Disease Ontology:DOID:769); hyperthyroidism (Disease Ontology:DOID:7998); osteoarthritis (Disease Ontology:DOID:8398); ulcerative colitis (Disease Ontology:DOID:8577); vascular dementia (Disease Ontology:DOID:8725); diabetic retinopathy (Disease Ontology:DOID:8947); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352); vesicoureteral reflux (Disease Ontology:DOID:9620); diabetic neuropathy (Disease Ontology:DOID:9743); obesity (Disease Ontology:DOID:9970)",
        "pathway": " (dre:245701)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "15602699;15644436;15797461;15880261;16169945;37061125;37471641;38747698;39081296;39413646",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
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        "reported_c_glycosites_with_glycan": 0,
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        "missing_score": 10000,
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        "ec_number_list": "2.7.10.1;2.7.10.2;2.7.11.1;2.7.12.1;2.7.12.2",
        "go_molecular_function": "GO:0005009 insulin receptor activity;GO:0005524 ATP binding;GO:0005520 insulin-like growth factor binding;GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0043560 insulin receptor substrate binding",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030424 axon;GO:0005899 insulin receptor complex",
        "go_biological_process": "GO:0048752 semicircular canal morphogenesis;GO:0007507 heart development;GO:0043410 positive regulation of MAPK cascade;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0042593 glucose homeostasis",
        "synthesized_glycan_count": 0,
        "hit_score": 1.1,
        "record_id": "A0AC58HSB5-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58HSQ3-1",
        "uniprot_id": "A0AC58HSQ3_DANRE",
        "mass": 60192.0,
        "length": 555,
        "protein_name": "Pyruvate kinase",
        "gene_name": "pkma",
        "organism": "Zebrafish",
        "refseq_name": "pyruvate kinase PKM isoform X2",
        "refseq_ac": "XP_073785021",
        "gene_names_uniprotkb": "pkma; cb1029; fj33f03; pkm2a; pkm2; wu:fj33f03",
        "gene_names_refseq": "cb1029; fj33f03; pkm2a; pkm2; pkma; wu:fj33f03",
        "protein_names_uniprotkb": "Pyruvate kinase; 2.7.1.40",
        "protein_names_refseq": "pyruvate kinase PKM isoform X2",
        "tax_id": 7955,
        "disease": "disease of metabolism (Disease Ontology:DOID:0014667); hypertension (Disease Ontology:DOID:10763)",
        "pathway": " (R-DRE-6798695);  (R-DRE-70171);  (R-DRE-70268);  (R-DRE-9861718)",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "ec_number_list": "4.2.99.18;5.6.2.4;2.7.1.11;2.7.1.40;3.6.4.13;1.1.1.205;5.4.2.11;5.4.2.4;2.7.1.35;1.13.11.34;3.2.1.31;3.6.5.-;2.3.2.27;3.6.4.6;4.1.2.13;2.7.11.24;1.11.1.6",
        "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016301 kinase activity;GO:0030955 potassium ion binding;GO:0004743 pyruvate kinase activity",
        "go_cellular_component": "GO:0005737 cytoplasm",
        "go_biological_process": "GO:0032869 cellular response to insulin stimulus;GO:0002040 sprouting angiogenesis;GO:0006096 glycolytic process",
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        "record_id": "A0AC58HSQ3-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58HSR8-1",
        "uniprot_id": "A0AC58HSR8_DANRE",
        "mass": 47234.0,
        "length": 414,
        "protein_name": "ATP-sensitive inward rectifier potassium channel 1a.1 isoform X1",
        "gene_name": "kcnj1a.1",
        "organism": "Zebrafish",
        "refseq_name": "ATP-sensitive inward rectifier potassium channel 1a.1 isoform X1",
        "refseq_ac": "XP_073785035",
        "gene_names_uniprotkb": "kcnj1a.1; kcnj1; romk2; wu:fl37c05; zgc:63534",
        "gene_names_refseq": "kcnj1a.1; kcnj1; romk2; wu:fl37c05; zgc:63534",
        "protein_names_uniprotkb": "ATP-sensitive inward rectifier potassium channel 1a.1 isoform X1",
        "protein_names_refseq": "ATP-sensitive inward rectifier potassium channel 1a.1 isoform X1",
        "tax_id": 7955,
        "disease": "Bartter disease type 2 (Disease Ontology:DOID:0110143); nephrotic syndrome (Disease Ontology:DOID:1184)",
        "pathway": " (dre:386933)",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "secondary_ac_list": "A0AC58HSS0",
        "ec_number_list": "2.7.11.1;1.5.1.2",
        "go_molecular_function": "GO:0005242 inward rectifier potassium channel activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0034702 monoatomic ion channel complex",
        "go_biological_process": "GO:0007399 nervous system development;GO:0034220 monoatomic ion transmembrane transport;GO:0034765 regulation of monoatomic ion transmembrane transport;GO:1990573 potassium ion import across plasma membrane",
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        "record_id": "A0AC58HSR8-1",
        "record_type": "protein"
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    {
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        "uniprot_id": "A0AC58HSY8_DANRE",
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        "length": 554,
        "protein_name": "Tripartite motif-containing protein 16 isoform X4",
        "gene_name": "ftr06",
        "organism": "Zebrafish",
        "refseq_name": "tripartite motif-containing protein 16 isoform X4",
        "refseq_ac": "XP_073785114",
        "gene_names_uniprotkb": "ftr06",
        "gene_names_refseq": "ftr06",
        "protein_names_uniprotkb": "Tripartite motif-containing protein 16 isoform X4",
        "protein_names_refseq": "tripartite motif-containing protein 16 isoform X4",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0008270 zinc ion binding",
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        "uniprot_id": "A0AC58HR68_DANRE",
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        "length": 319,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC141378550",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073784480",
        "gene_names_uniprotkb": "LOC141378550",
        "gene_names_refseq": "LOC141378550",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
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        "length": 429,
        "protein_name": "Protein FAM161A",
        "gene_name": "LOC141378567",
        "organism": "Zebrafish",
        "refseq_name": "protein FAM161A-like isoform X1",
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        "gene_names_uniprotkb": "LOC141378567",
        "gene_names_refseq": "LOC141378567",
        "protein_names_uniprotkb": "Protein FAM161A",
        "protein_names_refseq": "protein FAM161A-like isoform X1",
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        "length": 287,
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        "protein_name": "Myosin VIIAa isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Extracellular matrix serine protease secreted by pioneer neurons that plays a role in layering of neurons in the cerebral cortex and cerebellum by coordinating cell positioning during neurodevelopment. Regulates microtubule function in neurons and neuronal migration. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "length": 485,
        "protein_name": "Protein C-ets-1 isoform X1",
        "gene_name": "ets1",
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        "refseq_name": "protein C-ets-1 isoform 1",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588723.1505936.1, SRR32588727.3157261.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000018.1. On Aug 11, 2025 this sequence version replaced XP_073784905.1. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Recruitment of transcription factor ETS1 to activated accessible regions promotes the transcriptional program of cilia genes., [RefSeq, PubMed]",
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        "protein_name": "Sine oculis homeobox homolog 1a",
        "gene_name": "six9",
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        "protein_name": "Cyclin B1, like isoform X1",
        "gene_name": "ccnb1l",
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        "refseq_name": "cyclin B1, like isoform X1",
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        "gene_names_refseq": "ccnb1l; zgc:103540",
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        "protein_names_refseq": "cyclin B1, like isoform X1",
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        "length": 1140,
        "protein_name": "DNA damage-binding protein 1",
        "gene_name": "ddb1",
        "organism": "Zebrafish",
        "refseq_name": "DNA damage-binding protein 1",
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        "function": "##Evidence-Data-START## Transcript exon combination :: BC056837.1, JQ692623.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000018.1. On or before Jun 30, 2025 this sequence version replaced XP_073785085.1, NP_956920.1., [RefSeq]",
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        "go_biological_process": "GO:0034220 monoatomic ion transmembrane transport",
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        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
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        "gene_names_refseq": "homer2; zgc:111960; zmp:0000000677",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "missing_score": 10000,
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        "glyco_site_count": 5,
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        "go_molecular_function": "GO:0046556 alpha-L-arabinofuranosidase activity",
        "go_cellular_component": "GO:0005576 extracellular region",
        "go_biological_process": "GO:0048752 semicircular canal morphogenesis;GO:0032474 otolith morphogenesis;GO:0007605 sensory perception of sound;GO:0046373 L-arabinose metabolic process",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HWH3-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HV65-1",
        "uniprot_id": "A0AC58HV65_DANRE",
        "mass": 93677.0,
        "length": 842,
        "protein_name": "Extracellular calcium-sensing receptor-like isoform X2",
        "gene_name": "LOC100007210",
        "organism": "Zebrafish",
        "refseq_name": "extracellular calcium-sensing receptor-like isoform X2",
        "refseq_ac": "XP_073785885",
        "gene_names_uniprotkb": "LOC100007210",
        "gene_names_refseq": "LOC100007210",
        "protein_names_uniprotkb": "Extracellular calcium-sensing receptor-like isoform X2",
        "protein_names_refseq": "extracellular calcium-sensing receptor-like isoform X2",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100007210)",
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        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0004930 G protein-coupled receptor activity",
        "go_cellular_component": "GO:0005886 plasma membrane",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HV65-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58HWB6-1",
        "uniprot_id": "A0AC58HWB6_DANRE",
        "mass": 28825.0,
        "length": 264,
        "protein_name": "Meiotic recombination protein REC114 isoform X1",
        "gene_name": "si:ch1073-75f15.2",
        "organism": "Zebrafish",
        "refseq_name": "meiotic recombination protein REC114 isoform X1",
        "refseq_ac": "XP_073786249",
        "gene_names_uniprotkb": "si:ch1073-75f15.2",
        "gene_names_refseq": "si:ch1073-75f15.2",
        "protein_names_uniprotkb": "Meiotic recombination protein REC114 isoform X1",
        "protein_names_refseq": "meiotic recombination protein REC114 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:795419)",
        "pathway_count": 1,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "",
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        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HWB6-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HUR0-1",
        "uniprot_id": "A0AC58HUR0_DANRE",
        "mass": 301487.0,
        "length": 2616,
        "protein_name": "Spectrin beta chain, non-erythrocytic 1",
        "gene_name": "sptbn4b",
        "organism": "Zebrafish",
        "refseq_name": "spectrin beta chain, non-erythrocytic 4 isoform X1",
        "refseq_ac": "XP_073785723",
        "gene_names_uniprotkb": "sptbn4b",
        "gene_names_refseq": "sptbn4b",
        "protein_names_uniprotkb": "Spectrin beta chain, non-erythrocytic 1; Beta-II spectrin; Fodrin beta chain",
        "protein_names_refseq": "spectrin beta chain, non-erythrocytic 4 isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:100148730)",
        "pathway_count": 1,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. Plays a critical role in central nervous system development and function., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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        "predicted_o_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "GO:0003779 actin binding;GO:0005543 phospholipid binding",
        "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0016020 membrane",
        "go_biological_process": "GO:0051693 actin filament capping",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HUR0-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HX37-1",
        "uniprot_id": "A0AC58HX37_DANRE",
        "mass": 33587.0,
        "length": 298,
        "protein_name": "palmitoyl-CoA hydrolase",
        "gene_name": "ppt2b",
        "organism": "Zebrafish",
        "refseq_name": "lysosomal thioesterase PPT2 isoform X1",
        "refseq_ac": "XP_073786537",
        "gene_names_uniprotkb": "ppt2b; ppt2; zgc:174932",
        "gene_names_refseq": "ppt2b; ppt2; zgc:174932",
        "protein_names_uniprotkb": "palmitoyl-CoA hydrolase; 3.1.2.2",
        "protein_names_refseq": "lysosomal thioesterase PPT2 isoform X1",
        "tax_id": 7955,
        "disease": "neuronal ceroid lipofuscinosis (Disease Ontology:DOID:14503)",
        "pathway": " (dre:100126133);  (R-DRE-75105)",
        "pathway_count": 2,
        "publication_count": 2,
        "publication_id_list": "11120825;27189481",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the cleavage of thioester bonds from S-palmitoyl-CoA or S-palmitoyl-N-acetylcysteamine (unbranched structures) but does not have activity against palmitoylcysteine or palmitoylated proteins, branched structures or bulky head groups. Conversely, hydrolyzes both long and short chain fatty acyl-CoA substrate., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "missing_score": 10000,
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        "secondary_ac_list": "",
        "ec_number_list": "3.1.2.2;3.1.2.22",
        "go_molecular_function": "GO:0016790 thiolester hydrolase activity;GO:0098599 palmitoyl hydrolase activity",
        "go_cellular_component": "GO:0005576 extracellular region;GO:0005764 lysosome",
        "go_biological_process": "",
        "synthesized_glycan_count": 0,
        "hit_score": 0.3,
        "record_id": "A0AC58HX37-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HV46-1",
        "uniprot_id": "A0AC58HV46_DANRE",
        "mass": 65222.0,
        "length": 572,
        "protein_name": "Neuronal acetylcholine receptor subunit alpha-3 isoform X2",
        "gene_name": "chrna3",
        "organism": "Zebrafish",
        "refseq_name": "neuronal acetylcholine receptor subunit alpha-3 isoform X2",
        "refseq_ac": "XP_073785858",
        "gene_names_uniprotkb": "chrna3",
        "gene_names_refseq": "chrna3",
        "protein_names_uniprotkb": "Neuronal acetylcholine receptor subunit alpha-3 isoform X2",
        "protein_names_refseq": "neuronal acetylcholine receptor subunit alpha-3 isoform X2",
        "tax_id": 7955,
        "disease": "alcohol dependence (Disease Ontology:DOID:0050741); nicotine dependence (Disease Ontology:DOID:0050742); stomach cancer (Disease Ontology:DOID:10534); lung cancer (Disease Ontology:DOID:1324); depressive disorder (Disease Ontology:DOID:1596); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); lung carcinoma (Disease Ontology:DOID:3905); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); lung small cell carcinoma (Disease Ontology:DOID:5409); cocaine dependence (Disease Ontology:DOID:9975)",
        "pathway": " (dre:568467)",
        "pathway_count": 1,
        "publication_count": 0,
        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
        "predicted_n_glycosites": 0,
        "predicted_o_glycosites": 0,
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        "ec_number_list": "2.7.11.1;1.5.1.2",
        "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity",
        "go_cellular_component": "GO:0005886 plasma membrane;GO:0005892 acetylcholine-gated channel complex;GO:0045202 synapse;GO:0045211 postsynaptic membrane;GO:0043005 neuron projection",
        "go_biological_process": "GO:0007271 synaptic transmission, cholinergic;GO:0007274 neuromuscular synaptic transmission;GO:0035094 response to nicotine;GO:0095500 acetylcholine receptor signaling pathway;GO:0034220 monoatomic ion transmembrane transport",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HV46-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HU68-1",
        "uniprot_id": "A0AC58HU68_DANRE",
        "mass": 47628.0,
        "length": 431,
        "protein_name": "WT1 transcription factor b isoform X1",
        "gene_name": "wt1b",
        "organism": "Zebrafish",
        "refseq_name": "WT1 transcription factor b isoform X1",
        "refseq_ac": "XP_073785534",
        "gene_names_uniprotkb": "wt1b; si:ch211-160j6.3; wt1; zgc:152697",
        "gene_names_refseq": "si:ch211-160j6.3; wt1b; wt1; zgc:152697",
        "protein_names_uniprotkb": "WT1 transcription factor b isoform X1",
        "protein_names_refseq": "WT1 transcription factor b isoform X1",
        "tax_id": 7955,
        "disease": "Frasier syndrome (Disease Ontology:DOID:0050438); ovarian serous carcinoma (Disease Ontology:DOID:0050933); nephrotic syndrome type 4 (Disease Ontology:DOID:0080383); Alzheimer's disease (Disease Ontology:DOID:10652); lung cancer (Disease Ontology:DOID:1324); endometrial cancer (Disease Ontology:DOID:1380); breast cancer (Disease Ontology:DOID:1612); malignant mesothelioma (Disease Ontology:DOID:1790); nephroblastoma (Disease Ontology:DOID:2154); Denys-Drash syndrome (Disease Ontology:DOID:3764); congenital diaphragmatic hernia (Disease Ontology:DOID:3827); renal Wilms' tumor (Disease Ontology:DOID:5176); chronic kidney disease (Disease Ontology:DOID:784)",
        "pathway": " (dre:568416)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "16292775;17651719;17953490;18282108;18992736;36172839;36247002;36359386;36513650;36659918",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "protein_name": "Sodium/nucleoside cotransporter",
        "gene_name": "slc28a1",
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        "refseq_name": "sodium/nucleoside cotransporter 1 isoform X1",
        "refseq_ac": "XP_073785597",
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        "gene_names_refseq": "si:dkey-24l11.1; slc28a1; zgc:158842",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_molecular_function": "GO:0005415 nucleoside:sodium symporter activity",
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        "length": 550,
        "protein_name": "Thromboxane-A synthase",
        "gene_name": "tbxas1",
        "organism": "Zebrafish",
        "refseq_name": "thromboxane-A synthase isoform X1",
        "refseq_ac": "XP_073785684",
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        "protein_names_uniprotkb": "Thromboxane-A synthase; 1.14.14.1; 4.2.1.152; 5.3.99.5; Cytochrome P450 5A1; Hydroperoxy icosatetraenoate dehydratase",
        "protein_names_refseq": "thromboxane-A synthase isoform X1",
        "tax_id": 7955,
        "disease": "Ghosal hematodiaphyseal syndrome (Disease Ontology:DOID:0112251); cerebral infarction (Disease Ontology:DOID:3526)",
        "pathway": " (dre:792041);  (R-DRE-211979);  (R-DRE-2162123)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the conversion of prostaglandin H2 (PGH2) to thromboxane A2 (TXA2), a potent inducer of blood vessel constriction and platelet aggregation. Also cleaves PGH2 to 12-hydroxy-heptadecatrienoicacid (12-HHT) and malondialdehyde, which is known to act as a mediator of DNA damage. 12-HHT and malondialdehyde are formed stoichiometrically in the same amounts as TXA2. Additionally, displays dehydratase activity, toward (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate (15(S)-HPETE) producing 15-KETE and 15-HETE., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "ec_number_list": "1.14.14.1;4.2.1.152;5.3.99.5;5.3.99.4;5.3.99.3",
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        "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane",
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        "uniprot_canonical_ac": "A0AC58HUK7-1",
        "uniprot_id": "A0AC58HUK7_DANRE",
        "mass": 27583.0,
        "length": 245,
        "protein_name": "Troponin I, skeletal, slow c isoform X1",
        "gene_name": "tnni1c",
        "organism": "Zebrafish",
        "refseq_name": "troponin I, skeletal, slow c isoform X1",
        "refseq_ac": "XP_073785669",
        "gene_names_uniprotkb": "tnni1c; CH1073-380L12.2; im:7161636; zgc:153662",
        "gene_names_refseq": "CH1073-380L12.2; im:7161636; tnni1c; zgc:153662",
        "protein_names_uniprotkb": "Troponin I, skeletal, slow c isoform X1",
        "protein_names_refseq": "troponin I, skeletal, slow c isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity., [UniProtKB, UniProtKB]",
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        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58HUL0-1",
        "uniprot_id": "A0AC58HUL0_DANRE",
        "mass": 52027.0,
        "length": 474,
        "protein_name": "SH2 domain-containing adapter protein F isoform X1",
        "gene_name": "zgc:158464",
        "organism": "Zebrafish",
        "refseq_name": "SH2 domain-containing adapter protein F isoform 1",
        "refseq_ac": "NP_001429064",
        "gene_names_uniprotkb": "zgc:158464; si:ch73-116f3.3",
        "gene_names_refseq": "si:ch73-116f3.3; zgc:158464",
        "protein_names_uniprotkb": "SH2 domain-containing adapter protein F isoform X1",
        "protein_names_refseq": "SH2 domain-containing adapter protein F isoform 1",
        "tax_id": 7955,
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588727.2543723.1, SRR32588728.26452077.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000018.1. On Jul 28, 2025 this sequence version replaced XP_073785675.1., [RefSeq]",
        "predicted_glycosites": 0,
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        "record_id": "A0AC58HUL0-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58HUM1-1",
        "uniprot_id": "A0AC58HUM1_DANRE",
        "mass": 91743.0,
        "length": 818,
        "protein_name": "Phosphodiesterase",
        "gene_name": "pde8a",
        "organism": "Zebrafish",
        "refseq_name": "high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1",
        "refseq_ac": "XP_073785681",
        "gene_names_uniprotkb": "pde8a; zgc:158458",
        "gene_names_refseq": "pde8a; zgc:158458",
        "protein_names_uniprotkb": "Phosphodiesterase; 3.1.4.-",
        "protein_names_refseq": "high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:791145)",
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        "publication_id_list": "26469318;27189481",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development. Binding to RAF1 reduces RAF1 'Ser-259' inhibitory-phosphorylation and stimulates RAF1-dependent EGF-activated ERK-signaling. Protects against cell death induced by hydrogen peroxide and staurosporine., [UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0046872 metal ion binding;GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity;GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity",
        "go_cellular_component": "",
        "go_biological_process": "GO:0007165 signal transduction;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0006355 regulation of DNA-templated transcription;GO:0071364 cellular response to epidermal growth factor stimulus;GO:0006198 cAMP catabolic process",
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        "length": 600,
        "protein_name": "Uncharacterized protein",
        "gene_name": "LOC141378665",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
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        "gene_names_uniprotkb": "LOC141378665",
        "gene_names_refseq": "LOC141378665",
        "protein_names_uniprotkb": "Uncharacterized protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "uniprot_canonical_ac": "A0AC58HUQ6-1",
        "uniprot_id": "A0AC58HUQ6_DANRE",
        "mass": 41908.0,
        "length": 370,
        "protein_name": "C-X-C chemokine receptor type 5",
        "gene_name": "cxcr5",
        "organism": "Zebrafish",
        "refseq_name": "LOW QUALITY PROTEIN: C-X-C chemokine receptor type 5",
        "refseq_ac": "XP_073785701",
        "gene_names_uniprotkb": "cxcr5",
        "gene_names_refseq": "cxcr5",
        "protein_names_uniprotkb": "C-X-C chemokine receptor type 5",
        "protein_names_refseq": "LOW QUALITY PROTEIN: C-X-C chemokine receptor type 5",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## internal stop codons        :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Uncharacterized protein",
        "gene_name": "LOC141378674",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
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        "gene_names_uniprotkb": "LOC141378674",
        "gene_names_refseq": "LOC141378674",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "uncharacterized protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "gene_name": "LOC141375069",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
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        "gene_names_uniprotkb": "LOC141375069",
        "gene_names_refseq": "LOC141375069",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "uncharacterized protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "record_id": "A0AC58HUW0-1",
        "record_type": "protein"
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        "uniprot_canonical_ac": "A0AC58HV04-1",
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        "protein_name": "CXADR-like membrane protein",
        "gene_name": "clmpb",
        "organism": "Zebrafish",
        "refseq_name": "CXADR-like membrane protein",
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        "gene_names_uniprotkb": "clmpb",
        "gene_names_refseq": "clmpb",
        "protein_names_uniprotkb": "CXADR-like membrane protein",
        "protein_names_refseq": "CXADR-like membrane protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "record_id": "A0AC58HV04-1",
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        "uniprot_canonical_ac": "A0AC58HV08-1",
        "uniprot_id": "A0AC58HV08_DANRE",
        "mass": 76680.0,
        "length": 672,
        "protein_name": "Gypsy retrotransposon integrase-like protein 1",
        "gene_name": "LOC141378681",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
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        "gene_names_uniprotkb": "LOC141378681",
        "gene_names_refseq": "LOC141378681",
        "protein_names_uniprotkb": "Gypsy retrotransposon integrase-like protein 1",
        "protein_names_refseq": "uncharacterized protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "record_id": "A0AC58HV08-1",
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        "uniprot_canonical_ac": "A0AC58HV37-1",
        "uniprot_id": "A0AC58HV37_DANRE",
        "mass": 223252.0,
        "length": 2050,
        "protein_name": "Latent-transforming growth factor beta-binding protein 1",
        "gene_name": "ltbp4",
        "organism": "Zebrafish",
        "refseq_name": "latent-transforming growth factor beta-binding protein 4 isoform X1",
        "refseq_ac": "XP_073785826",
        "gene_names_uniprotkb": "ltbp4",
        "gene_names_refseq": "ltbp4",
        "protein_names_uniprotkb": "Latent-transforming growth factor beta-binding protein 1; Latent-transforming growth factor beta-binding protein 2; Latent-transforming growth factor beta-binding protein 4; Transforming growth factor beta-1-binding protein 1",
        "protein_names_refseq": "latent-transforming growth factor beta-binding protein 4 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta. Outcompeted by LRRC32/GARP for binding to LAP regulatory chain of TGF-beta., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; May play an integral structural role in elastic-fiber architectural organization and/or assembly., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "length": 81,
        "protein_name": "Uncharacterized protein C14orf132",
        "gene_name": "LOC108180053",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein C14orf132",
        "refseq_ac": "XP_073785857",
        "gene_names_uniprotkb": "LOC108180053",
        "gene_names_refseq": "LOC108180053",
        "protein_names_uniprotkb": "Uncharacterized protein C14orf132",
        "protein_names_refseq": "uncharacterized protein C14orf132",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "uniprot_canonical_ac": "A0AC58HV58-1",
        "uniprot_id": "A0AC58HV58_DANRE",
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        "length": 860,
        "protein_name": "Extracellular calcium-sensing receptor isoform X1",
        "gene_name": "olfcq8",
        "organism": "Zebrafish",
        "refseq_name": "extracellular calcium-sensing receptor isoform X1",
        "refseq_ac": "XP_073785882",
        "gene_names_uniprotkb": "olfcq8",
        "gene_names_refseq": "olfcq8",
        "protein_names_uniprotkb": "Extracellular calcium-sensing receptor isoform X1",
        "protein_names_refseq": "extracellular calcium-sensing receptor isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "length": 361,
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        "gene_name": "LOC137488271",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": "XP_073786069",
        "gene_names_uniprotkb": "LOC137488271",
        "gene_names_refseq": "LOC137488271",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "uncharacterized protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "uniprot_canonical_ac": "A0AC58HVX4-1",
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        "length": 1795,
        "protein_name": "Phosphoinositide phospholipase C",
        "gene_name": "plch1",
        "organism": "Zebrafish",
        "refseq_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 isoform X5",
        "refseq_ac": "XP_073786090",
        "gene_names_uniprotkb": "plch1",
        "gene_names_refseq": "plch1",
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        "protein_names_refseq": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 isoform X5",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. This phospholipase activity is very sensitive to calcium. May be important for formation and maintenance of the neuronal network in the postnatal brain., [UniProtKB, UniProtKB]",
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        "record_id": "A0AC58HVX4-1",
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        "protein_name": "Protein LEKR1 isoform X1",
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        "organism": "Zebrafish",
        "refseq_name": "protein LEKR1 isoform X1",
        "refseq_ac": "XP_073786091",
        "gene_names_uniprotkb": "lekr1",
        "gene_names_refseq": "lekr1",
        "protein_names_uniprotkb": "Protein LEKR1 isoform X1",
        "protein_names_refseq": "protein LEKR1 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "RRM domain-containing protein",
        "gene_name": "LOC108179987",
        "organism": "Zebrafish",
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        "gene_names_uniprotkb": "LOC108179987",
        "gene_names_refseq": "LOC108179987",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "length": 161,
        "protein_name": "alanine--tRNA ligase",
        "gene_name": "LOC100535229",
        "organism": "Zebrafish",
        "refseq_name": "alanine--tRNA ligase, cytoplasmic-like",
        "refseq_ac": "XP_073786081",
        "gene_names_uniprotkb": "LOC100535229",
        "gene_names_refseq": "LOC100535229",
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        "protein_names_refseq": "alanine--tRNA ligase, cytoplasmic-like",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "protein_name": "E3 SUMO-protein ligase ZBED1-like",
        "gene_name": "LOC141378747",
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        "refseq_name": "E3 SUMO-protein ligase ZBED1-like",
        "refseq_ac": "XP_073786102",
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        "gene_names_refseq": "LOC141378747",
        "protein_names_uniprotkb": "E3 SUMO-protein ligase ZBED1-like",
        "protein_names_refseq": "E3 SUMO-protein ligase ZBED1-like",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "gene_names_refseq": "LOC141378752",
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    },
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        "length": 294,
        "protein_name": "DUF6451 domain-containing protein",
        "gene_name": "LOC100535984",
        "organism": "Zebrafish",
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        "gene_names_uniprotkb": "LOC100535984",
        "gene_names_refseq": "LOC100535984",
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    {
        "uniprot_canonical_ac": "A0AC58HVY6-1",
        "uniprot_id": "A0AC58HVY6_DANRE",
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        "length": 321,
        "protein_name": "Uncharacterized protein isoform X1",
        "gene_name": "LOC141378765",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073786148",
        "gene_names_uniprotkb": "LOC141378765",
        "gene_names_refseq": "LOC141378765",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "record_id": "A0AC58HVY6-1",
        "record_type": "protein"
    },
    {
        "uniprot_canonical_ac": "A0AC58HVY7-1",
        "uniprot_id": "A0AC58HVY7_DANRE",
        "mass": 34400.0,
        "length": 308,
        "protein_name": "tRNA-splicing endonuclease subunit Sen34",
        "gene_name": "tsen34",
        "organism": "Zebrafish",
        "refseq_name": "tRNA-splicing endonuclease subunit Sen34 isoform 1",
        "refseq_ac": "NP_001373676",
        "gene_names_uniprotkb": "tsen34",
        "gene_names_refseq": "si:ch211-203b8.3; tsen34",
        "protein_names_uniprotkb": "tRNA-splicing endonuclease subunit Sen34; 4.6.1.16",
        "protein_names_refseq": "tRNA splicing endonuclease 34 homolog; tRNA-splicing endonuclease subunit Sen34 isoform 1",
        "tax_id": 7955,
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        "function": "##Evidence-Data-START## Transcript exon combination :: GDQQ01055218.1, SRR26395039.1107274.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708828, SAMEA708832 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000018.1. On or before Sep 17, 2025 this sequence version replaced XP_073786154.1, NP_001373676.1., [RefSeq]; Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body., [UniProtKB, UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0004519 endonuclease activity",
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        "hit_score": 0.1,
        "record_id": "A0AC58HVY7-1",
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        "uniprot_canonical_ac": "A0AC58HVY9-1",
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        "mass": 76520.0,
        "length": 686,
        "protein_name": "non-specific serine/threonine protein kinase",
        "gene_name": "LOC559991",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
        "refseq_ac": "XP_073786105",
        "gene_names_uniprotkb": "LOC559991",
        "gene_names_refseq": "LOC559991",
        "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1",
        "protein_names_refseq": "uncharacterized protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "biomarker_type": "",
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        "protein_name": "Apoptosis-associated speck-like protein containing a CARD",
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        "gene_name": "LOC141378779",
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        "gene_names_refseq": "LOC141378779",
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        "protein_names_refseq": "uncharacterized protein isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "length": 525,
        "protein_name": "AT-rich interactive domain-containing protein 3",
        "gene_name": "si:dkey-205h23.1",
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        "refseq_ac": "XP_073786224",
        "gene_names_uniprotkb": "si:dkey-205h23.1",
        "gene_names_refseq": "si:dkey-205h23.1",
        "protein_names_uniprotkb": "AT-rich interactive domain-containing protein 3; ARID domain-containing protein",
        "protein_names_refseq": "AT-rich interactive domain-containing protein 3B isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Transcription factor., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
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        "length": 588,
        "protein_name": "Semaphorin-7A isoform X1",
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        "organism": "Zebrafish",
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        "length": 847,
        "protein_name": "threonine--tRNA ligase",
        "gene_name": "tars3",
        "organism": "Zebrafish",
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        "refseq_ac": "XP_073786215",
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        "protein_names_refseq": "threonine--tRNA ligase 1, cytoplasmic isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged tRNA(Thr) via its editing domain, at the post-transfer stage., [UniProtKB, UniProtKB, UniProtKB]",
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        "ec_number_list": "6.1.1.3",
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        "length": 453,
        "protein_name": "Tyrosine-protein kinase",
        "gene_name": "cskl",
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        "gene_names_uniprotkb": "cskl",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "synthesized_glycan_count": 0,
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        "record_id": "A0AC58HWA2-1",
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        "uniprot_canonical_ac": "A0AC58HWA7-1",
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        "mass": 206092.0,
        "length": 1809,
        "protein_name": "alpha-glucosidase",
        "gene_name": "si",
        "organism": "Zebrafish",
        "refseq_name": "sucrase-isomaltase, intestinal",
        "refseq_ac": "XP_073786286",
        "gene_names_uniprotkb": "si",
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        "protein_names_uniprotkb": "alpha-glucosidase; 3.2.1.20; Maltase",
        "protein_names_refseq": "sucrase-isomaltase, intestinal",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58HWC8-1",
        "uniprot_id": "A0AC58HWC8_DANRE",
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        "length": 783,
        "protein_name": "F-BAR and double SH3 domains protein 2",
        "gene_name": "fchsd2",
        "organism": "Zebrafish",
        "refseq_name": "F-BAR and double SH3 domains protein 2 isoform X1",
        "refseq_ac": "XP_073786264",
        "gene_names_uniprotkb": "fchsd2",
        "gene_names_refseq": "fchsd2",
        "protein_names_uniprotkb": "F-BAR and double SH3 domains protein 2; Protein nervous wreck 1; SH3 multiple domains protein 3",
        "protein_names_refseq": "F-BAR and double SH3 domains protein 2 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Adapter protein that plays a role in endocytosis via clathrin-coated pits. Contributes to the internalization of cell surface receptors, such as integrin ITGB1 and transferrin receptor. Promotes endocytosis of EGFR in cancer cells, and thereby contributes to the down-regulation of EGFR signaling. Recruited to clathrin-coated pits during a mid-to-late stage of assembly, where it is required for normal progress from U-shaped intermediate stage pits to terminal, omega-shaped pits. Binds to membranes enriched in phosphatidylinositol 3,4-bisphosphate or phosphatidylinositol 3,4,5-trisphosphate. When bound to membranes, promotes actin polymerization via its interaction with WAS and/or WASL which leads to the activation of the Arp2/3 complex. Does not promote actin polymerisation in the absence of membranes., [UniProtKB, UniProtKB, UniProtKB]",
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        "length": 1257,
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        "gene_name": "LOC141378791",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073786276",
        "gene_names_uniprotkb": "LOC141378791",
        "gene_names_refseq": "LOC141378791",
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        "protein_names_refseq": "uncharacterized protein isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "length": 351,
        "protein_name": "P2Y purinoceptor 2",
        "gene_name": "p2ry2.2",
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        "refseq_ac": "XP_073786280",
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        "gene_names_refseq": "p2ry2.2",
        "protein_names_uniprotkb": "P2Y purinoceptor 2",
        "protein_names_refseq": "P2Y purinoceptor 2-like isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "protein_name": "Uncharacterized protein si:ch73-167i17.7",
        "gene_name": "si:ch73-167i17.7",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein si:ch73-167i17.7",
        "refseq_ac": "XP_073786296",
        "gene_names_uniprotkb": "si:ch73-167i17.7",
        "gene_names_refseq": "si:ch73-167i17.7",
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        "protein_names_refseq": "uncharacterized protein si:ch73-167i17.7",
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        "length": 2036,
        "protein_name": "ZP domain-containing protein",
        "gene_name": "LOC100535405",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
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        "gene_names_uniprotkb": "LOC100535405",
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        "protein_names_refseq": "uncharacterized protein",
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        "gene_name": "LOC141378797",
        "organism": "Zebrafish",
        "refseq_name": "uncharacterized protein",
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        "gene_names_uniprotkb": "LOC141378797",
        "gene_names_refseq": "LOC141378797",
        "protein_names_uniprotkb": "Uncharacterized protein",
        "protein_names_refseq": "uncharacterized protein",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "refseq_ac": "NP_001429232",
        "gene_names_uniprotkb": "thap7; im:7136959; si:ch211-282e16.1",
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        "protein_names_refseq": "THAP domain-containing protein 7 isoform 2",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588730.458441.1, SRR32588735.3638395.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000019.1. On Jul 31, 2025 this sequence version replaced XP_073786495.1., [RefSeq]",
        "predicted_glycosites": 0,
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        "gene_names_refseq": "pde1cb",
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        "protein_names_refseq": "dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X1",
        "tax_id": 7955,
        "disease": "autosomal dominant nonsyndromic deafness 74 (Disease Ontology:DOID:0112165)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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    {
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        "uniprot_id": "A0AC58HYH8_DANRE",
        "mass": 87299.0,
        "length": 772,
        "protein_name": "Death domain-associated protein 6",
        "gene_name": "daxx",
        "organism": "Zebrafish",
        "refseq_name": "death domain-associated protein 6 isoform 1",
        "refseq_ac": "NP_001429252",
        "gene_names_uniprotkb": "daxx; si:dz179b20.7; wu:fd15c03",
        "gene_names_refseq": "daxx; si:dz179b20.7; wu:fd15c03",
        "protein_names_uniprotkb": "Death domain-associated protein 6; Daxx",
        "protein_names_refseq": "death domain-associated protein 6 isoform 1; death-associated protein 6; fas-binding",
        "tax_id": 7955,
        "disease": "oral squamous cell carcinoma (Disease Ontology:DOID:0050866); lung non-squamous non-small cell carcinoma (Disease Ontology:DOID:0080521); prostate cancer (Disease Ontology:DOID:10283); stomach cancer (Disease Ontology:DOID:10534); appendiceal neoplasm (Disease Ontology:DOID:11240); leukemia (Disease Ontology:DOID:1240); neuroendocrine tumor (Disease Ontology:DOID:169); pancreatic endocrine carcinoma (Disease Ontology:DOID:1798); islet cell tumor (Disease Ontology:DOID:1799); ovary epithelial cancer (Disease Ontology:DOID:2152); transient cerebral ischemia (Disease Ontology:DOID:224); colon adenocarcinoma (Disease Ontology:DOID:234); transitional cell carcinoma (Disease Ontology:DOID:2671); clear cell adenocarcinoma (Disease Ontology:DOID:4468)",
        "pathway": " (dre:561006)",
        "pathway_count": 1,
        "publication_count": 10,
        "publication_id_list": "10799891;10849368;11220619;12869198;15520368;23028350;25862973;26469318;27493218;33279476",
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        "function": "##Evidence-Data-START## Transcript exon combination :: SRR32588732.18081704.1, SRR32588731.2201043.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505373, SAMEA3505374 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000019.1. On Jul 31, 2025 this sequence version replaced XP_073787038.1. Publication Note:  This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications., [RefSeq]; Daxx mRNA was detected in embryonic development from 6 h to 120 h and in all 11 selected zebrafish tissues, and Daxx expression first increased and then decreased during megalocytivirus infectious spleen and kidney necrosis virus infection., [RefSeq, PubMed]",
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        "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0000775 chromosome, centromeric region;GO:0016605 PML body",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006915 apoptotic process;GO:0045892 negative regulation of DNA-templated transcription;GO:0006325 chromatin organization;GO:0042981 regulation of apoptotic process",
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        "hit_score": 1.1,
        "record_id": "A0AC58HYH8-1",
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    {
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        "uniprot_id": "A0AC58HYF2_DANRE",
        "mass": 62802.0,
        "length": 527,
        "protein_name": "dual-specificity kinase",
        "gene_name": "clk2a",
        "organism": "Zebrafish",
        "refseq_name": "dual specificity protein kinase CLK2 isoform X1",
        "refseq_ac": "XP_073787013",
        "gene_names_uniprotkb": "clk2a; clk2; fb20c02; si:ch211-81a5.7; wu:fb20c02",
        "gene_names_refseq": "clk2a; clk2; fb20c02; si:ch211-81a5.7; wu:fb20c02",
        "protein_names_uniprotkb": "dual-specificity kinase; 2.7.12.1",
        "protein_names_refseq": "dual specificity protein kinase CLK2 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "secondary_ac_list": "A0AC58HYG4;A0AC58HYG6",
        "ec_number_list": "2.7.11.1;2.7.11.13;2.7.11.25;2.7.10.1;2.7.10.2;2.7.11.22;2.7.11.21;2.7.11.17;2.7.12.1;2.7.12.2;2.7.11.24;2.7.11.23;2.7.1.150;2.7.11.12;2.7.11.39;2.7.11.11;2.7.1.153;2.7.1.137;2.7.1.154;2.7.11.26;2.7.11.31",
        "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004712 protein serine/threonine/tyrosine kinase activity;GO:0016301 kinase activity",
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        "uniprot_canonical_ac": "A0AC58HZ16-1",
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        "length": 338,
        "protein_name": "Retinol-DH_like_SDR_c domain-containing protein isoform X1",
        "gene_name": "crdh; zgc:153441",
        "organism": "Zebrafish",
        "refseq_name": "retinol-DH_like_SDR_c domain-containing protein isoform X1",
        "refseq_ac": "XP_073787220",
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        "gene_names_refseq": "si:dkey-200h23.4; zgc:153441",
        "protein_names_uniprotkb": "Retinol-DH_like_SDR_c domain-containing protein isoform X1",
        "protein_names_refseq": "retinol-DH_like_SDR_c domain-containing protein isoform X1",
        "tax_id": 7955,
        "disease": "Leber congenital amaurosis (Disease Ontology:DOID:14791)",
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        "protein_name": "Uncharacterized protein si:ch73-281i18.3 isoform X1",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_cellular_component": "GO:0015630 microtubule cytoskeleton",
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        "protein_name": "Interferon-inducible GTPase 5-like isoform X1",
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        "protein_names_refseq": "interferon-inducible GTPase 5-like isoform X1",
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        "protein_name": "Uncharacterized protein isoform X1",
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        "refseq_name": "uncharacterized protein isoform X1",
        "refseq_ac": "XP_073787555",
        "gene_names_uniprotkb": "LOC100004582",
        "gene_names_refseq": "LOC100004582",
        "protein_names_uniprotkb": "Uncharacterized protein isoform X1",
        "protein_names_refseq": "uncharacterized protein isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "go_cellular_component": "GO:0009897 external side of plasma membrane",
        "go_biological_process": "GO:0006955 immune response;GO:0007166 cell surface receptor signaling pathway;GO:0031295 T cell costimulation;GO:0042130 negative regulation of T cell proliferation;GO:0071222 cellular response to lipopolysaccharide",
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        "uniprot_id": "A0AC58HXG3_DANRE",
        "mass": 100987.0,
        "length": 885,
        "protein_name": "Solute carrier family 52, riboflavin transporter, member 2 isoform X1",
        "gene_name": "slc52a2",
        "organism": "Zebrafish",
        "refseq_name": "solute carrier family 52, riboflavin transporter, member 2 isoform X1",
        "refseq_ac": "XP_073786673",
        "gene_names_uniprotkb": "slc52a2; fc11c06; wu:fc11c06; zgc:63774",
        "gene_names_refseq": "fc11c06; slc52a2; wu:fc11c06; zgc:63774",
        "protein_names_uniprotkb": "Solute carrier family 52, riboflavin transporter, member 2 isoform X1",
        "protein_names_refseq": "solute carrier family 52, riboflavin transporter, member 2 isoform X1",
        "tax_id": 7955,
        "disease": "Brown-Vialetto-Van Laere syndrome 2 (Disease Ontology:DOID:0080786)",
        "pathway": " (dre:323832)",
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        "publication_id_list": "27189481",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism., [UniProtKB, UniProtKB]",
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        "go_molecular_function": "GO:0032217 riboflavin transmembrane transporter activity",
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        "length": 568,
        "protein_name": "Tripartite motif-containing protein 16 isoform X1",
        "gene_name": "ftr87",
        "organism": "Zebrafish",
        "refseq_name": "tripartite motif-containing protein 16 isoform X1",
        "refseq_ac": "XP_073787172",
        "gene_names_uniprotkb": "ftr87",
        "gene_names_refseq": "ftr87",
        "protein_names_uniprotkb": "Tripartite motif-containing protein 16 isoform X1",
        "protein_names_refseq": "tripartite motif-containing protein 16 isoform X1",
        "tax_id": 7955,
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "go_molecular_function": "GO:0008270 zinc ion binding",
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        "uniprot_id": "A0AC58HYG8_DANRE",
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        "length": 585,
        "protein_name": "Chondroitin sulfate proteoglycan 5b isoform X1",
        "gene_name": "cspg5b",
        "organism": "Zebrafish",
        "refseq_name": "chondroitin sulfate proteoglycan 5b isoform X1",
        "refseq_ac": "XP_073787018",
        "gene_names_uniprotkb": "cspg5b; si:dkeyp-114f9.4",
        "gene_names_refseq": "cspg5b; si:dkeyp-114f9.4",
        "protein_names_uniprotkb": "Chondroitin sulfate proteoglycan 5b isoform X1",
        "protein_names_refseq": "chondroitin sulfate proteoglycan 5b isoform X1",
        "tax_id": 7955,
        "disease": "",
        "pathway": " (dre:559358)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 1,
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        "go_cellular_component": "GO:0045211 postsynaptic membrane",
        "go_biological_process": "GO:0031103 axon regeneration;GO:0106091 glial cell projection elongation",
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        "uniprot_canonical_ac": "A0AC58I022-1",
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        "mass": 324588.0,
        "length": 2945,
        "protein_name": "[histone H3]-lysine(4) N-methyltransferase",
        "gene_name": "kmt2ba",
        "organism": "Zebrafish",
        "refseq_name": "histone-lysine N-methyltransferase 2B isoform X1",
        "refseq_ac": "XP_073787587",
        "gene_names_uniprotkb": "kmt2ba",
        "gene_names_refseq": "kmt2ba",
        "protein_names_uniprotkb": "[histone H3]-lysine(4) N-methyltransferase; 2.1.1.364",
        "protein_names_refseq": "histone-lysine N-methyltransferase 2B isoform X1",
        "tax_id": 7955,
        "disease": "colorectal adenocarcinoma (Disease Ontology:DOID:0050861); dystonia 28, childhood-onset (Disease Ontology:DOID:0060936); autosomal dominant intellectual developmental disorder 68 (Disease Ontology:DOID:0061041); prostate cancer (Disease Ontology:DOID:10283); breast cancer (Disease Ontology:DOID:1612); congenital heart disease (Disease Ontology:DOID:1682); hepatocellular carcinoma (Disease Ontology:DOID:684)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
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        "length": 1250,
        "protein_name": "Superkiller complex protein 2 isoform X1",
        "gene_name": "skic2",
        "organism": "Zebrafish",
        "refseq_name": "superkiller complex protein 2 isoform X1",
        "refseq_ac": "XP_073787022",
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        "gene_names_refseq": "fb70b07; skic2; skiv2l; wu:fb70b07",
        "protein_names_uniprotkb": "Superkiller complex protein 2 isoform X1",
        "protein_names_refseq": "superkiller complex protein 2 isoform X1",
        "tax_id": 7955,
        "disease": "trichohepatoenteric syndrome 2 (Disease Ontology:DOID:0111416)",
        "pathway": " (dre:559653);  (R-DRE-429958)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "ec_number_list": "2.3.2.-;2.3.2.27;3.6.4.-;4.2.99.18;5.6.2.4;5.6.2.3;3.6.4.12;3.6.4.13;2.7.4.3;7.6.2.2;5.6.1.6;7.6.2.3;3.6.1.5;3.6.4.6;3.6.1.15;3.6.4.10;5.6.2.-;2.7.7.7;2.7.7.49;5.6.2.5;3.6.5.-;3.6.1.-",
        "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003724 RNA helicase activity",
        "go_cellular_component": "GO:0055087 Ski complex;GO:0005737 cytoplasm",
        "go_biological_process": "GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay;GO:0006402 mRNA catabolic process",
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        "hit_score": 0.5,
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        "uniprot_id": "A0AC58HYG5_DANRE",
        "mass": 54221.0,
        "length": 493,
        "protein_name": "[tau protein] kinase",
        "gene_name": "gsk3aa",
        "organism": "Zebrafish",
        "refseq_name": "glycogen synthase kinase 3 alpha a isoform X1",
        "refseq_ac": "XP_073787030",
        "gene_names_uniprotkb": "gsk3aa; sb:eu851; si:ch211-39e15.2; zgc:158379",
        "gene_names_refseq": "gsk3aa; sb:eu851; si:ch211-39e15.2; zgc:158379",
        "protein_names_uniprotkb": "[tau protein] kinase; 2.7.11.26",
        "protein_names_refseq": "glycogen synthase kinase 3 alpha a isoform X1",
        "tax_id": 7955,
        "disease": "amyotrophic lateral sclerosis (Disease Ontology:DOID:332)",
        "pathway": " (dre:560194)",
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        "publication_id_list": "25504979;26469318;27189481;28252024;29232857",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 0,
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        "secondary_ac_list": "",
        "ec_number_list": "2.7.11.26;2.7.11.1;2.7.11.31",
        "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0050321 tau-protein kinase activity;GO:0016301 kinase activity",
        "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0030424 axon",
        "go_biological_process": "GO:0030154 cell differentiation;GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0010508 positive regulation of autophagy;GO:0032007 negative regulation of TOR signaling;GO:0008286 insulin receptor signaling pathway",
        "synthesized_glycan_count": 0,
        "hit_score": 0.6,
        "record_id": "A0AC58HYG5-1",
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    {
        "uniprot_canonical_ac": "A0AC58HZY4-1",
        "uniprot_id": "A0AC58HZY4_DANRE",
        "mass": 76142.0,
        "length": 721,
        "protein_name": "POU domain protein",
        "gene_name": "pou2f2a",
        "organism": "Zebrafish",
        "refseq_name": "POU domain, class 2, transcription factor 2 isoform X1",
        "refseq_ac": "XP_073787549",
        "gene_names_uniprotkb": "pou2f2a",
        "gene_names_refseq": "pou2f2a",
        "protein_names_uniprotkb": "POU domain protein",
        "protein_names_refseq": "POU domain, class 2, transcription factor 2 isoform X1",
        "tax_id": 7955,
        "disease": "immune system disease (Disease Ontology:DOID:2914)",
        "pathway": " (dre:100537384)",
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        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]",
        "predicted_glycosites": 5,
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        "missing_score": 10000,
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        "secondary_ac_list": "",
        "ec_number_list": "",
        "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding",
        "go_cellular_component": "GO:0005634 nucleus",
        "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II",
        "synthesized_glycan_count": 0,
        "hit_score": 0.1,
        "record_id": "A0AC58HZY4-1",
        "record_type": "protein"
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    {
        "uniprot_canonical_ac": "A0AC58HZZ1-1",
        "uniprot_id": "A0AC58HZZ1_DANRE",
        "mass": 60919.0,
        "length": 546,
        "protein_name": "Squalene monooxygenase",
        "gene_name": "sqleb",
        "organism": "Zebrafish",
        "refseq_name": "squalene monooxygenase isoform X1",
        "refseq_ac": "XP_073787558",
        "gene_names_uniprotkb": "sqleb",
        "gene_names_refseq": "sqleb",
        "protein_names_uniprotkb": "Squalene monooxygenase; 1.14.14.17",
        "protein_names_refseq": "squalene monooxygenase isoform X1",
        "tax_id": 7955,
        "disease": "cancer (Disease Ontology:DOID:162)",
        "pathway": " (dre:565329)",
        "pathway_count": 1,
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        "publication_id_list": "",
        "class_list": "",
        "function": "##Genome-Annotation-Data-START## Annotation Provider         :: NCBI RefSeq Annotation Status           :: Full annotation Annotation Name             :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated          :: Gene; mRNA; CDS; ncRNA Annotation Date             :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ:  This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length., [RefSeq]; Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]",
        "predicted_glycosites": 0,
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