[ { "uniprot_canonical_ac": "Q71TY3-1", "uniprot_id": "RS27_RAT", "mass": 9461.0, "length": 84, "protein_name": "Small ribosomal subunit protein eS27", "gene_name": "Rps27", "organism": "Rat", "refseq_name": "small ribosomal subunit protein eS27", "refseq_ac": "NP_446049", "gene_names_uniprotkb": "Rps27; S27-1", "gene_names_refseq": "Rps27", "protein_names_uniprotkb": "Small ribosomal subunit protein eS27; 40S ribosomal protein S27", "protein_names_refseq": "40S ribosomal protein S27; small ribosomal subunit protein eS27", "tax_id": 10116, "disease": "", "pathway": " (rno:94266); (R-RNO-141430); (R-RNO-141444); (R-RNO-156827); (R-RNO-1799339); (R-RNO-2467813); (R-RNO-2500257); (R-RNO-5663220); (R-RNO-6791226); (R-RNO-68877); (R-RNO-72649); (R-RNO-72689); (R-RNO-72695); (R-RNO-72702); (R-RNO-72706); (R-RNO-9648025); (R-RNO-975956); (R-RNO-975957); (R-RNO-9954714); (R-RNO-9954716)", "pathway_count": 20, "publication_count": 3, "publication_id_list": "10820185;22673903;38843836", "class_list": "", "function": "Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Required for proper rRNA processing and maturation of 18S rRNAs. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0008270 zinc ion binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0098982 GABA-ergic synapse;GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0006364 rRNA processing;GO:0042274 ribosomal small subunit biogenesis;GO:0000028 ribosomal small subunit assembly;GO:0140236 translation at presynapse;GO:0140242 translation at postsynapse", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q71TY3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q765I2-1", "uniprot_id": "UTS2B_RAT", "mass": 13341.0, "length": 118, "protein_name": "Urotensin-2B", "gene_name": "Uts2b", "organism": "Rat", "refseq_name": "urotensin-2B precursor", "refseq_ac": "NP_937766", "gene_names_uniprotkb": "Uts2b; Urp; Uts2d", "gene_names_refseq": "U2B; Urp; Uts2b; Uts2d", "protein_names_uniprotkb": "Urotensin-2B; U-IIB; UIIB; Urotensin II-related peptide; Urotensin IIB; Urotensin-2 domain-containing protein", "protein_names_refseq": "U-IIB; UIIB; urotensin 2 domain containing; urotensin II-related peptide; urotensin IIB; urotensin-2 domain-containing protein; urotensin-2B precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:378939); (R-RNO-375276); (R-RNO-416476)", "pathway_count": 3, "publication_count": 10, "publication_id_list": "14550283;14621188;15476951;16951045;17628210;18955095;19463745;22039515;22044114;24478001", "class_list": "", "function": "Central urotensin II may play a role in the pathogenesis of hypertension in SHR rats, [RefSeq, PubMed]; In the aorta, expression levels of urotensin II-related peptide mRNA was significantly elevated in 11-12-week-old SHR compared with age-matched WKY, similarly to those in the kidney., [RefSeq, PubMed]; Increased expression of urotensin II-related peptide in kidney with hypertension or renal failure, [RefSeq, PubMed]; Potent vasoconstrictor., [UniProtKB, PubMed]; Remarkable cellular and subcellular distribution led us to test the effect of URP on the GnRH-induced gonadotrophins release in the anterior pituitary, and to discuss its putative role at the level of the median eminence, [RefSeq, PubMed]; Study demonstrated that UII and URP binding sites are totally overlapping and that these sites were functional in regions bordering the fourth ventricle; data support a role for UII/URP at the interface between brain parenchyma and cerebrospinal fluid, [RefSeq, PubMed]; The long-lasting vasoconstriction induced by hU-II alone is PKC dependent and associated with PKC-theta phosphorylation., [RefSeq, PubMed]; These results suggest that urotensin II-related peptide is the endogenous and functional ligand for the urotensin II receptor GPR14 in the rat and mouse, and possibly in the human., [RefSeq, PubMed]; U-II and URP can differentially modulate nuclear UT functions such as gene expression, and both ligands can reach the internal cellular space through a receptor-independent mechanism, [RefSeq, PubMed]; URP is the endogenous and functional ligand for UII receptor in the rat, [RefSeq, PubMed]; URP is the endogenous and functional ligand for urotensin II receptor in the rat. (REVIEW) Review article, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001664 G protein-coupled receptor binding;GO:0005179 hormone activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0008217 regulation of blood pressure;GO:0097746 blood vessel diameter maintenance", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q765I2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q76EQ0-1", "uniprot_id": "SRR_RAT", "mass": 35693.0, "length": 333, "protein_name": "Serine racemase", "gene_name": "Srr", "organism": "Rat", "refseq_name": "serine racemase", "refseq_ac": "NP_942052", "gene_names_uniprotkb": "Srr", "gene_names_refseq": "Srr", "protein_names_uniprotkb": "Serine racemase; 4.3.1.17; 4.3.1.18; 5.1.1.18; D-serine ammonia-lyase; D-serine dehydratase; L-serine ammonia-lyase; L-serine dehydratase", "protein_names_refseq": "D-serine ammonia-lyase; D-serine dehydratase; L-serine ammonia-lyase; L-serine dehydratase; serine racemase", "tax_id": 10116, "disease": "schizophrenia (Disease Ontology:DOID:5419)", "pathway": " (rno:303306); (R-RNO-977347)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "12946565;16713567;17880399;19380732;20106978;26505919;26553873;27387750;27693471;38761177", "class_list": "", "function": "In aging cerebellum, oxidative DNA stress was associated with reduced serine racemase expression., [RefSeq, PubMed]; Pyridoxal-5'-phosphate (PLP)-dependent enzyme that catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors (PubMed:16713567, PubMed:20106978). In addition to racemization, has dehydratase activity towards both L-serine and D-serine, a two-step reaction in which the hydroxyl group of serine is eliminated to produce aminoacrylate (2-aminoprop-2-enoate), and then the aminoacrylate (an unstable intermediate) is deaminated by nonenzymatic hydrolysis to produce pyruvate (By similarity)., [UniProtKB, PubMed, UniProtKB, PubMed]; Results indicate that SRR indeed acts as a d-Asp biosynthetic enzyme in some organs and/or tissues, and also provide evidences that there should be some additional enzyme for d-Asp synthesis in mammals., [RefSeq, PubMed]; Serine racemase expression profile in the prefrontal cortex and hippocampal subregions during aging in male and female rats., [RefSeq, PubMed]; Study to demonstrate that serine racemase inhibitor alleviates neuronal ischemic injury. Serine racemase inhibition acts on the neurovascular unit as a neuroprotectant and ameliorant of reductions in regional cerebral blood flow., [RefSeq, PubMed]; That nuclear translocation of SR provides a fail-safe mechanism to prevent or limit secondary NMDAR-mediated toxicity in nearby synapses. Erratum:[J Biol Chem. 2016 Feb 5;291(6):2630. doi: 10.1074/jbc.A115.699496. Radzishevisky, Inna [corrected to Radzishevsky, Inna]. PMID: 26851299], [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "4.3.1.17;4.3.1.19;5.1.1.3;4.3.1.18;5.1.1.18", "go_molecular_function": "GO:0008721 D-serine ammonia-lyase activity;GO:0018114 threonine racemase activity;GO:0030378 serine racemase activity;GO:0000287 magnesium ion binding;GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0043025 neuronal cell body;GO:0045177 apical part of cell", "go_biological_process": "GO:0042866 pyruvate biosynthetic process;GO:1901986 response to ketamine;GO:0070179 D-serine biosynthetic process;GO:0070178 D-serine metabolic process;GO:0032496 response to lipopolysaccharide", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q76EQ0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q78EG7-1", "uniprot_id": "TP4A1_RAT", "mass": 19815.0, "length": 173, "protein_name": "Protein tyrosine phosphatase type IVA 1", "gene_name": "Ptp4a1", "organism": "Rat", "refseq_name": "protein tyrosine phosphatase type IVA 1", "refseq_ac": "NP_113767", "gene_names_uniprotkb": "Ptp4a1; Prl1", "gene_names_refseq": "PRL-1; Ptp4a1", "protein_names_uniprotkb": "Protein tyrosine phosphatase type IVA 1; 3.1.3.48; PRL-1; Protein-tyrosine phosphatase 4a1; Protein-tyrosine phosphatase of regenerating liver 1", "protein_names_refseq": "protein tyrosine phosphatase 4a1-like; protein tyrosine phosphatase type IVA 1; protein tyrosine phosphatase type IVA, member 1; protein-tyrosine phosphatase of regenerating liver 1", "tax_id": 10116, "disease": "", "pathway": " (rno:29463)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10679780;10960362;16142898;17032584;34689832;35255961;8196618;8840018", "class_list": "", "function": "Activation of the EGFR-PI3K-CaM pathway by PRL-1-overexpressing placenta-derived mesenchymal stem cells ameliorates liver cirrhosis via ER stress-dependent calcium. Publication Status: Online-Only, [RefSeq, PubMed]; Genes induced by FSH in rat Sertoli cells would also show hormonal regulation during rat folliculogenesis, [RefSeq, PubMed]; Increased phosphatase regenerating liver-1 trigger vascular remodeling in injured ovary via platelet-derived growth factor signaling pathway. Publication Status: Online-Only, [RefSeq, PubMed]; Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q4QRA5;Q8VH48", "ec_number_list": "3.1.3.48;2.7.10.1;3.1.3.16;3.1.3.2;3.1.3.21;3.1.3.18;3.1.3.67;3.1.3.-;3.1.3.27;3.1.3.5", "go_molecular_function": "GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005769 early endosome;GO:0005783 endoplasmic reticulum;GO:0005819 spindle", "go_biological_process": "GO:0030335 positive regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q78EG7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q794C0-1", "uniprot_id": "VA0E1_RAT", "mass": 9340.0, "length": 81, "protein_name": "V-type proton ATPase subunit e 1", "gene_name": "Atp6v0e1", "organism": "Rat", "refseq_name": "V-type proton ATPase subunit e 1", "refseq_ac": "NP_446030", "gene_names_uniprotkb": "Atp6v0e1; Atp6v0e; Dsr1", "gene_names_refseq": "Atp6k; Atp6v0e1; Atp6v0e; Dsr-1A; dsr-1", "protein_names_uniprotkb": "V-type proton ATPase subunit e 1; D-serine-regulated transcript 1 protein; DSR-1; V-ATPase 9.2 kDa membrane accessory protein; V-ATPase M9.2 subunit; V-ATPase subunit e 1; Vacuolar proton pump subunit e 1", "protein_names_refseq": "ATPase, H+ transporting, V0 subunit E; ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1; ATPase, H+ transporting, lysosomal V0 subunit E1; ATPase, H+ transporting, lysosomal, V0 subunit e1; D-serine-regulated transcript 1 protein; V-ATPase 9.2 kDa membrane accessory protein; V-ATPase M9.2 subunit; V-ATPase subunit e 1; V-type proton ATPase subunit e 1; vacuolar proton pump subunit e 1; vacuolar proton-ATPase subunit M9.2", "tax_id": 10116, "disease": "", "pathway": " (rno:94170); (R-RNO-1222556); (R-RNO-77387); (R-RNO-917977); (R-RNO-9639288); (R-RNO-983712)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "11162653", "class_list": "", "function": "Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it promotes acidification of the extracellular environment (By similarity). The V-ATPase complex also acts as an activator for mTORC1 on lysosomal membrane by promoting the guanine nucleotide exchange factor (GEF) of the Ragulator complex, thereby enabling mTORC1 recruitment (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046961 proton-transporting ATPase activity, rotational mechanism", "go_cellular_component": "GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain;GO:0033179 proton-transporting V-type ATPase, V0 domain", "go_biological_process": "GO:0043200 response to amino acid;GO:1902600 proton transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q794C0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7M6Z3-1", "uniprot_id": "SMYD2_RAT", "mass": 49648.0, "length": 433, "protein_name": "N-lysine methyltransferase SMYD2", "gene_name": "Smyd2", "organism": "Rat", "refseq_name": "N-lysine methyltransferase SMYD2", "refseq_ac": "NP_996733", "gene_names_uniprotkb": "Smyd2", "gene_names_refseq": "HSKM-B; Smyd2", "protein_names_uniprotkb": "N-lysine methyltransferase SMYD2; 2.1.1.-; 2.1.1.354; Histone methyltransferase SMYD2; SET and MYND domain-containing protein 2", "protein_names_refseq": "N-lysine methyltransferase SMYD2; SET and MYND domain-containing protein 2; histone methyltransferase SMYD2", "tax_id": 10116, "disease": "", "pathway": " (rno:289372); (R-RNO-3214841); (R-RNO-6804760)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "12783626;22673903;30337525;32096186;38770649", "class_list": "", "function": "LncRNA NEAT1 promotes cardiac hypertrophy through microRNA-19a-3p/SMYD2 axis., [RefSeq, PubMed]; Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically trimethylates histone H3 'Lys-4' (H3K4me3) in vivo. The activity requires interaction with HSP90alpha. Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'., [UniProtKB, UniProtKB]; SMYD2 glutathionylation is a novel molecular mechanism by which reactive oxygen species contribute to sarcomere destabilization. Publication Status: Online-Only, [RefSeq, PubMed]; SMYD2-Methylated PPARgamma Facilitates Hypoxia-Induced Pulmonary Hypertension by Activating Mitophagy., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.1.1.361;2.1.1.357;2.1.1.359;2.1.1.367;2.1.1.-;2.1.1.354;2.1.1.355;2.1.1.362", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000993 RNA polymerase II complex binding;GO:0002039 p53 binding;GO:0046975 histone H3K36 methyltransferase activity;GO:0016279 protein-lysine N-methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0007507 heart development;GO:0008285 negative regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q7M6Z3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7TM96-1", "uniprot_id": "ZN622_RAT", "mass": 43890.0, "length": 386, "protein_name": "Cytoplasmic 60S subunit biogenesis factor ZNF622", "gene_name": "Znf622", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Znf622; Ac1133; Ac2-061; Zfp622", "gene_names_refseq": "", "protein_names_uniprotkb": "Cytoplasmic 60S subunit biogenesis factor ZNF622; Liver regeneration-related protein LRRG121; Zinc finger protein 622", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Pre-60S-associated cytoplasmic factor involved in the cytoplasmic maturation of the 60S subunit., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:1990275 preribosome binding;GO:0008270 zinc ion binding;GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005829 cytosol;GO:0030687 preribosome, large subunit precursor", "go_biological_process": "GO:0043065 positive regulation of apoptotic process;GO:0043410 positive regulation of MAPK cascade;GO:0046330 positive regulation of JNK cascade;GO:0042273 ribosomal large subunit biogenesis;GO:0033674 positive regulation of kinase activity", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q7TM96-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7TN40-1", "uniprot_id": "MRGRE_RAT", "mass": 34511.0, "length": 309, "protein_name": "Mas-related G protein-coupled receptor member E", "gene_name": "Mrgpre", "organism": "Rat", "refseq_name": "mas-related G-protein coupled receptor member E", "refseq_ac": "NP_001002288", "gene_names_uniprotkb": "Mrgpre; Mrge", "gene_names_refseq": "Mgrf; MrgE; Mrgpre", "protein_names_uniprotkb": "Mas-related G protein-coupled receptor member E", "protein_names_refseq": "MAS-related G-protein coupled receptor, member E; MAS-related GPR, member E; MAS-related gene E; Mas-related G protein-coupled receptor f; mas-related G-protein coupled receptor member E", "tax_id": 10116, "disease": "", "pathway": " (rno:404660)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12909716;16282220;29393594", "class_list": "", "function": "G protein-coupled receptor for L-tryptophanocholate (Trp-CA), an amino-acid-conjugated bile acid produced by the microbiome, which regulates glucose homeostasis. Expressed in enteroendocrine L cells of the gut epithelium: Trp-CA binding causes a conformation change that triggers signaling via G(s) G protein, mediating activation of adenylate cyclase activity. In addition to G(s), MRGPRE also associates with beta-arrestin-1 (ARRB1), promoting phosphorylation of ALDOA. Both G(s) and beta-arrestin-1 signaling pathways improves glucose tolerance by enhancing GLP-1 secretion., [UniProtKB, UniProtKB]; Interactions between rMrgD and rMrgE modulate the function of rMrgD., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0038182 G protein-coupled bile acid receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0007186 G protein-coupled receptor signaling pathway;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0001678 intracellular glucose homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q7TN40-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7TN41-1", "uniprot_id": "MRGRD_RAT", "mass": 35830.0, "length": 319, "protein_name": "Mas-related G protein-coupled receptor member D", "gene_name": "Mrgprd", "organism": "Rat", "refseq_name": "mas-related G-protein coupled receptor member D", "refseq_ac": "NP_001001506", "gene_names_uniprotkb": "Mrgprd; Mrgd", "gene_names_refseq": "Mgrd; Mrgd; Mrgprd; TGR7", "protein_names_uniprotkb": "Mas-related G protein-coupled receptor member D; Beta-alanine receptor; G protein-coupled receptor TGR7", "protein_names_refseq": "G-protein coupled receptor TGR7; MAS-related G-protein coupled receptor, member D; MAS-related GPR, member D; MAS-related gene D; MRGD G protein-coupled receptor; Mas-related G protein-coupled receptor d; beta-alanine receptor; mas-related G-protein coupled receptor member D", "tax_id": 10116, "disease": "dilated cardiomyopathy (Disease Ontology:DOID:12930)", "pathway": " (rno:293648)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "12909716;15037633;16282220;17442834;24078284;33129833", "class_list": "", "function": "Activation of recombinant rat MrgD protein promotes opening of the endogenous calcium-activated chloride channels in Xenopus oocytes., [RefSeq, PubMed]; Alamandine through MrgD receptor induces antidepressant-like effect in transgenic rats with low brain angiotensinogen., [RefSeq, PubMed]; G protein-coupled receptor that acts as a mediator of peripheral pain and itch sensations. Activated by various ligands, such as beta-alanine, beta-aminoisobutyrate, angiotensin 1-7, alamandine and allantoin, causing a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors (By similarity). MRGPRD is both coupled to G(q) and G(i) G proteins: G(q) coupling activates phospholipase C-beta, releasing diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) second messengers, while G(i) coupling mediates inhibition of adenylate cyclase activity (By similarity). MRGPRD is specifically expressed in neurons that innervate the epidermis and acts as a key mediator of skin stimuli, such as itch, pain and mechanical stimuli. Required to maintain skin homeostasis in response to irritant dermatitis by initiating a signaling that promotes glutamate release, inhibiting mast cell hyperresponsiveness and skin inflammation. Required to prevent cardiomyocyte hypertrophy following activation by alamandine, a decarboxylation product of angiotensin 1-7. Acts as a receptor for allantoin in dorsal root ganglion neurons, eliciting chronic itch (pruritus) (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Interactions between rMrgD and rMrgE modulate the function of rMrgD., [RefSeq, PubMed]; TGR7 participates in the modulation of neuropathic pain, [RefSeq, PubMed]; We provide evidence for a novel interaction between MrgD and KCNQ/M-type potassium channels that contributes to an increase in excitability of DRG neurons and thus may enhance the signaling of primary afferent nociceptive neurons., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6L788", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0008528 G protein-coupled peptide receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0002033 angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q7TN41-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7TN49-1", "uniprot_id": "MRGRA_RAT", "mass": 34346.0, "length": 304, "protein_name": "Mas-related G protein-coupled receptor member A", "gene_name": "Mrgpra; Mrgprx3", "organism": "Rat", "refseq_name": "mas-related G-protein coupled receptor member A", "refseq_ac": "NP_665730", "gene_names_uniprotkb": "Mrgpra; Mrgprx3; Mrga", "gene_names_refseq": "Mgrg1; MrgA; Mrga10; Mrgpra; Mrgprx3", "protein_names_uniprotkb": "Mas-related G protein-coupled receptor member A", "protein_names_refseq": "G-protein coupled receptor; MAS-related G-protein coupled receptor, member A; MAS-related GPR, member X3; Mas-related G protein-coupled receptor g1; Mas-related gene A; adenine receptor; mas-related G-protein coupled receptor member A; nuclear receptor MrgA10 RF-amide G protein-coupled receptor; rc 56.1.3", "tax_id": 10116, "disease": "", "pathway": " (rno:252960)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "12084918;12909716;15604413;17728165;35770633", "class_list": "", "function": "Kinetics of adenine binding to the adenine receptor of the rat brain cortex., [RefSeq, PubMed]; Orphan receptor activated by a subset of RFamide-family neuropeptides such as FLRF-amide and FMRF-amide. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. May regulate the function of nociceptive neurons by modulation of pain perception (By similarity)., [UniProtKB]; Results validate the predicted structure for MrgA and should be useful for seeking other small molecule agonists and antagonists., [RefSeq, PubMed]; [The distribution of Mas-related G protein-coupled receptor A in cerebrospinal fluid-contacting nucleus of normal rats and its up-regulation in neuropathic pain]., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5FVU1;Q91YB7", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0005525 GTP binding;GO:0008188 neuropeptide receptor activity;GO:0031409 pigment binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:1905237 response to cyclosporin A;GO:1901652 response to peptide;GO:0160025 sensory perception of itch", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q7TN49-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7TN50-1", "uniprot_id": "MRGB8_RAT", "mass": 37041.0, "length": 328, "protein_name": "Mas-related G protein-coupled receptor member B8", "gene_name": "Mrgprb8", "organism": "Rat", "refseq_name": "mas-related G-protein coupled receptor member B8", "refseq_ac": "NP_001002283", "gene_names_uniprotkb": "Mrgprb8; Mrgb8", "gene_names_refseq": "MrgB8; Mrgprb13; Mrgprb8", "protein_names_uniprotkb": "Mas-related G protein-coupled receptor member B8", "protein_names_refseq": "MAS-related G protein-coupled receptor, member B8; MAS-related gene B8; mas-related G-protein coupled receptor member B8", "tax_id": 10116, "disease": "", "pathway": " (rno:404643)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "12909716", "class_list": "", "function": "Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q7TN50-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7TNK3-1", "uniprot_id": "ZNF24_RAT", "mass": 41910.0, "length": 368, "protein_name": "Zinc finger protein 24", "gene_name": "Znf24", "organism": "Rat", "refseq_name": "zinc finger protein 24", "refseq_ac": "NP_892000", "gene_names_uniprotkb": "Znf24; Zfp191; Znf191", "gene_names_refseq": "Zfp191; Zfp24; Znf24", "protein_names_uniprotkb": "Zinc finger protein 24; Zfp-191; Zinc finger protein 191", "protein_names_refseq": "zfp-191; zinc finger protein 191; zinc finger protein 24", "tax_id": 10116, "disease": "", "pathway": " (rno:360204)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5'-TCAT-3' DNA sequence. Has transcription repressor activity in vitro (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0042552 myelination;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q7TNK3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7TPB1-1", "uniprot_id": "TCPD_RAT", "mass": 58099.0, "length": 539, "protein_name": "T-complex protein 1 subunit delta", "gene_name": "Cct4", "organism": "Rat", "refseq_name": "T-complex protein 1 subunit delta", "refseq_ac": "NP_877966", "gene_names_uniprotkb": "Cct4", "gene_names_refseq": "Cct4", "protein_names_uniprotkb": "T-complex protein 1 subunit delta; 3.6.1.-; CCT-delta; TCP-1-delta", "protein_names_refseq": "CCT-delta; T-complex protein 1 subunit delta; TCP-1-delta; chaperonin containing Tcp1, subunit 4 (delta); chaperonin subunit 4 (delta)", "tax_id": 10116, "disease": "hereditary sensory and autonomic neuropathy (Disease Ontology:DOID:0050548); intrinsic cardiomyopathy (Disease Ontology:DOID:0060036)", "pathway": " (rno:29374); (R-RNO-390471); (R-RNO-5620922); (R-RNO-6814122)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "12874111;15193290;25124038", "class_list": "", "function": "C450Y CCT4 is defective in protein stability., [RefSeq, PubMed]; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; The mutation in Cct4 underlies cutaneous nerve degeneration in mutilated-foot rats., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.6.2.3;3.6.4.13;3.6.4.12;2.7.11.1;3.6.1.5;3.6.4.10;3.6.4.-;2.3.2.27;5.6.2.4;3.6.5.-;5.6.2.-;3.1.-.-;2.7.7.7;2.7.7.49;3.1.13.1;4.2.99.18;7.6.2.2;7.6.2.3;7.6.2.-;5.6.1.6;7.2.2.-;3.6.1.15;3.6.4.6;3.1.3.1;3.9.1.1;6.1.1.12;3.6.1.-;2.7.4.3;3.1.4.-;3.4.24.-;3.6.-.-;2.7.1.91;2.3.1.-;3.4.21.53;5.6.2.5", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0051082 unfolded protein binding;GO:0016887 ATP hydrolysis activity;GO:0044183 protein folding chaperone", "go_cellular_component": "GO:0005813 centrosome;GO:0005829 cytosol;GO:0005874 microtubule;GO:0042470 melanosome;GO:0044297 cell body", "go_biological_process": "GO:0090666 scaRNA localization to Cajal body;GO:0007339 binding of sperm to zona pellucida;GO:0032212 positive regulation of telomere maintenance via telomerase;GO:0050821 protein stabilization;GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q7TPB1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7TPF1-1", "uniprot_id": "SMAGP_RAT", "mass": 10712.0, "length": 97, "protein_name": "Small cell adhesion glycoprotein", "gene_name": "Smagp", "organism": "Rat", "refseq_name": "small cell adhesion glycoprotein", "refseq_ac": "NP_877969", "gene_names_uniprotkb": "Smagp", "gene_names_refseq": "Smagp", "protein_names_uniprotkb": "Small cell adhesion glycoprotein; Small transmembrane and glycosylated protein", "protein_names_refseq": "small cell adhesion glycoprotein; small cell transmembrane and glycosylated protein; small trans-membrane and glycosylated protein", "tax_id": 10116, "disease": "", "pathway": " (rno:300236)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15021913;15986429;22673903", "class_list": "", "function": "May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation., [UniProtKB, PubMed]", "predicted_glycosites": 6, "predicted_n_glycosites": 0, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030054 cell junction;GO:0030659 cytoplasmic vesicle membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q7TPF1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7TQ82-1", "uniprot_id": "RT10_RAT", "mass": 17960.0, "length": 155, "protein_name": "Small ribosomal subunit protein uS10m", "gene_name": "Mrps10", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Mrps10; Ac1179", "gene_names_refseq": "", "protein_names_uniprotkb": "Small ribosomal subunit protein uS10m; 28S ribosomal protein S10, mitochondrial; Liver regeneration-related protein LRRG099; MRP-S10; S10mt", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:363187); (R-RNO-5389840); (R-RNO-5419276); (R-RNO-9837999); (R-RNO-9937383)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005739 mitochondrion", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q7TQ82-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7TSB7-1", "uniprot_id": "KISS1_RAT", "mass": 14188.0, "length": 130, "protein_name": "Metastasis-suppressor KiSS-1", "gene_name": "Kiss1", "organism": "Rat", "refseq_name": "metastasis-suppressor KiSS-1 precursor", "refseq_ac": "NP_859043", "gene_names_uniprotkb": "Kiss1", "gene_names_refseq": "Eseptin; Kiss1", "protein_names_uniprotkb": "Metastasis-suppressor KiSS-1; Kisspeptin-1; Metastin45-54", "protein_names_refseq": "Kiss1 variant E1a-E2b-E3; Kiss1 variant E1b-E2a-E3; Kiss1 variant E1b-E2b-E3; MLL septin-like fusion; kisspeptin-1; metastasis-suppressor KiSS-1 precursor; metastasis-suppressor KiSS-1; metastin", "tax_id": 10116, "disease": "hypogonadotropic hypogonadism 13 with or without anosmia (Disease Ontology:DOID:0090073); pre-eclampsia (Disease Ontology:DOID:10591); urinary bladder cancer (Disease Ontology:DOID:11054); transitional cell carcinoma (Disease Ontology:DOID:2671); endometrial carcinoma (Disease Ontology:DOID:2871); invasive ductal carcinoma (Disease Ontology:DOID:3008); ovarian carcinoma (Disease Ontology:DOID:4001); trophoblastic neoplasm (Disease Ontology:DOID:4085)", "pathway": " (rno:289023); (R-RNO-375276); (R-RNO-416476)", "pathway_count": 3, "publication_count": 13, "publication_id_list": "12531466;15157736;15219839;15242985;15500545;15593369;15637288;17698953;35729637;36099331;36114434;36273897;37230188", "class_list": "", "function": "Acetate restores hypothalamic-adipose kisspeptin status in a rat model of PCOS by suppression of NLRP3 immunoreactivity., [RefSeq, PubMed]; Binds the G protein-coupled receptor KISS1R/GPR54 and triggers G protein-coupled receptor signaling via activation of G(q) and phosphatidylinositol hydrolysis by phospholipase C (By similarity). Binding to the receptor also activates beta-arrestin-dependent signaling resulting in ERK1/2 phosphorylation (By similarity). Activation of the receptor inhibits cell proliferation and cell migration, and is involved in the regulation of trophoblast invasion during early stages of pregnancy. Is also involved in the modulation of airway smooth muscle cells migration (By similarity). In bone tissue, activation of KISS1R by kisspeptin-10 recruits phosphatase DUSP18 and SRC to the KISS1R C-terminus through a G(q)-dependent signaling pathway. This leads to DUSP18-mediated dephosphorylation of SRC, down-regulation of osteoclast differentiation and activity, and consequently suppression of bone resorption (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Epigenetic modification of Kiss1 gene expression in the AVPV is essential for female reproductive aging., [RefSeq, PubMed]; Hyperandrogenism induces proportional changes in the expression of Kiss-1, Tac2, and DynA in hypothalamic KNDy neurons. Publication Status: Online-Only, [RefSeq, PubMed]; Intrauterine LPS inhibited arcuate Kiss1 expression, LH pulses, and ovarian function in rats. Publication Status: Online-Only, [RefSeq, PubMed]; Kisspeptin and lactational anestrus: Current understanding and future prospects., [RefSeq, PubMed]; Kisspeptins are ligands for the G protein-coupled receptor KISS1R/GPR54 (By similarity). The hypothalamic KISS1/KISS1R signaling system plays a central role in the regulation of the hypothalamic-pituitary-gonadal reproductive axis by modulating the secretion of gonadotropin-releasing hormone (GnRH) from GnRH neurons (PubMed:15219839, PubMed:15242985, PubMed:15500545, PubMed:15637288, PubMed:17698953). In these neurons, kisspeptin binding to its receptor activates G(q)-dependent signaling, leading to phospholipase C (PLC) activation, and hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2). The subsequent rise in intracellular calcium levels results in the inhibition of inward rectifier potassium channels and activation of TRPC-like cation channels, leading to GnRH neurons depolarization and stimulation. In addition to this pathway, kisspeptin also triggers G(q)-independent signaling via beta-arrestin, leading to MAPK cascade activation and ERK1/ERK2 phosphorylation (By similarity). Kisspeptins are also involved in the regulation of other processes including cell growth, cell proliferation and cell migration (By similarity)., [UniProtKB, PubMed, UniProtKB, PubMed, PubMed, PubMed, PubMed]; Metastin-like immunoreactivity is present in the spinal cord and medulla oblongata, and the pattern of distribution in these regions suggests that this novel peptide may participate in autonomic and sensory neural signaling., [RefSeq, PubMed]; Metastin/OT7T175 signaling may participate in implantation of the mammalian embryo, placenta formation, and maintenance of pregnancy, [RefSeq, PubMed]; Receptor binding triggers G protein-coupled receptor signaling via activation of G(q) and phosphatidylinositol 4,5-bisphosphate (PIP2) hydrolysis by phospholipase C., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001664 G protein-coupled receptor binding;GO:0048018 receptor ligand activity;GO:0031773 kisspeptin receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0043025 neuronal cell body;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0008285 negative regulation of cell population proliferation;GO:0043410 positive regulation of MAPK cascade;GO:0060112 generation of ovulation cycle rhythm", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q7TSB7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7TSV3-1", "uniprot_id": "ZMY19_RAT", "mass": 26433.0, "length": 227, "protein_name": "Zinc finger MYND domain-containing protein 19", "gene_name": "Zmynd19", "organism": "Rat", "refseq_name": "zinc finger MYND domain-containing protein 19", "refseq_ac": "NP_942065", "gene_names_uniprotkb": "Zmynd19; Mizip", "gene_names_refseq": "Zmynd19; mizip", "protein_names_uniprotkb": "Zinc finger MYND domain-containing protein 19; MCH-R1-interacting zinc finger protein; Melanin-concentrating hormone receptor 1-interacting zinc finger protein", "protein_names_refseq": "MCH-R1-interacting zinc finger protein; melanin-concentrating hormone receptor 1 interacting zinc-finger protein; zinc finger MYND domain-containing protein 19-like; zinc finger MYND domain-containing protein 19; zinc finger, MYND domain containing 19", "tax_id": 10116, "disease": "", "pathway": " (rno:311791)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12208518;15950311", "class_list": "", "function": "Data support the notion that MIZIP might interact with melanin-concentrating hormone receptor 1 (MCHR1) in a cell type specific manner in vivo, suggesting a role in the regulation of MCH signalling in distinct regions of the mammalian brain, [RefSeq, PubMed]; May be involved as a regulatory molecule in GPR24/MCH-R1 signaling., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0045202 synapse", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q7TSV3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7TSX5-1", "uniprot_id": "SMS1_RAT", "mass": 49014.0, "length": 419, "protein_name": "Phosphatidylcholine:ceramide cholinephosphotransferase 1", "gene_name": "Sgms1", "organism": "Rat", "refseq_name": "phosphatidylcholine:ceramide cholinephosphotransferase 1", "refseq_ac": "NP_852051", "gene_names_uniprotkb": "Sgms1; Mob; Tmem23", "gene_names_refseq": "Mob; Sgms1; Tmem23; mob-1", "protein_names_uniprotkb": "Phosphatidylcholine:ceramide cholinephosphotransferase 1; 2.7.8.27; Protein Mob; Sphingomyelin synthase 1; Transmembrane protein 23", "protein_names_refseq": "phosphatidylcholine:ceramide cholinephosphotransferase 1; protein Mob; transmembrane protein 23", "tax_id": 10116, "disease": "pulmonary edema (Disease Ontology:DOID:11396)", "pathway": " (rno:353229); (R-RNO-1660661)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "12353928;21980337;29294205", "class_list": "", "function": "In contrast to Sgms1, Sgms2 does not contain the multi-exon 5'-UTR but encodes circRNAs, which are composed of the coding region of the gene and are expressed at a low level., [RefSeq, PubMed]; Major sphingomyelin synthase at the Golgi apparatus. Catalyzes the reversible transfer of phosphocholine moiety in sphingomyelin biosynthesis: in the forward reaction transfers phosphocholine head group of phosphatidylcholine (PC) on to ceramide (CER) to form ceramide phosphocholine (sphingomyelin, SM) and diacylglycerol (DAG) as by-product, and in the reverse reaction transfers phosphocholine from SM to DAG to form PC and CER. The direction of the reaction depends on the levels of CER and DAG in Golgi membranes. Converts the newly synthesized CER, that is transported from the endoplasmic reticulum to the trans-Golgi by the Cer transport protein (CERT), to SM. Can form a heteromeric complex with glucosylceramide synthase (GCS) increasing SMS activity and reducing glucosylceramide synthesis, a critical mechanism that controls the metabolic fate of CER in the Golgi (By similarity). Does not use free phosphorylcholine or CDP-choline as donor. Can also transfer phosphoethanolamine head group of phosphatidylethanolamine (PE) on to CER to form ceramide phosphoethanolamine (CPE) (By similarity). Regulates receptor-mediated signal transduction via mitogenic DAG and proapoptotic CER, as well as via SM, a structural component of membrane rafts that serve as platforms for signal transduction and protein sorting. Plays a role in secretory transport via regulation of DAG pool at the Golgi apparatus and its downstream effects on PRKD1 (PubMed:21980337)., [UniProtKB, PubMed, UniProtKB, UniProtKB]; Mob-1 and TNF-alpha interact to promote lung inflammation, [RefSeq, PubMed]; SMS1 and SMS2 are capable of regulating TGN-mediated protein trafficking and secretion, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.4.62;2.7.8.27", "go_molecular_function": "GO:0002950 ceramide phosphoethanolamine synthase activity;GO:0033188 sphingomyelin synthase activity;GO:0047493 ceramide cholinephosphotransferase activity;GO:0016301 kinase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane;GO:0000138 Golgi trans cisterna;GO:1990676 Golgi trans cisterna membrane", "go_biological_process": "GO:0006686 sphingomyelin biosynthetic process;GO:0010628 positive regulation of gene expression;GO:0046513 ceramide biosynthetic process;GO:0006915 apoptotic process;GO:0071222 cellular response to lipopolysaccharide", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q7TSX5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7TSX9-1", "uniprot_id": "ZAR1_RAT", "mass": 40357.0, "length": 361, "protein_name": "Zygote arrest protein 1", "gene_name": "Zar1", "organism": "Rat", "refseq_name": "zygote arrest protein 1", "refseq_ac": "NP_852050", "gene_names_uniprotkb": "Zar1", "gene_names_refseq": "Zar1", "protein_names_uniprotkb": "Zygote arrest protein 1", "protein_names_refseq": "oocyte-specific maternal effect factor; zygote arrest protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:353228)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "12773403", "class_list": "", "function": "The carboxyl-termini of these ZAR1 proteins contain an important functional domain that is conserved through vertebrate evolution and that may be necessary for normal female reproduction in the transition from oocyte to embryonic life., [RefSeq, PubMed]; mRNA-binding protein that mediates formation of MARDO (mitochondria-associated ribonucleoprotein domain), a membraneless compartment that stores maternal mRNAs in oocytes. MARDO assembly around mitochondria is directed by an increase in mitochondrial membrane potential during oocyte growth. Promotes formation of MARDO phase-separated membraneless compartment by undergoing liquid-liquid phase separation upon binding to maternal mRNAs. Binds to the 3'-UTR of maternal mRNAs. Maternal mRNAs stored in the MARDO are translationally repressed. Essential for female fertility and oocyte-to-embryo transition by coordinating maternal mRNA storage, translation and degradation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003730 mRNA 3'-UTR binding;GO:0140693 molecular condensate scaffold activity;GO:0140610 RNA sequestering activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0036464 cytoplasmic ribonucleoprotein granule;GO:0035770 ribonucleoprotein granule;GO:0043232 intracellular membraneless organelle", "go_biological_process": "GO:0048255 mRNA stabilization;GO:0017148 negative regulation of translation;GO:0001556 oocyte maturation;GO:0140694 membraneless organelle assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q7TSX9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q80VX4-1", "uniprot_id": "ZHX2_RAT", "mass": 92107.0, "length": 836, "protein_name": "Zinc fingers and homeoboxes protein 2", "gene_name": "Zhx2", "organism": "Rat", "refseq_name": "zinc fingers and homeoboxes protein 2", "refseq_ac": "NP_001257985", "gene_names_uniprotkb": "Zhx2; Afr1; Raf", "gene_names_refseq": "Zhx2", "protein_names_uniprotkb": "Zinc fingers and homeoboxes protein 2; AFP regulator 1; Alpha-fetoprotein regulator 1; Regulator of AFP; Zinc finger and homeodomain protein 2", "protein_names_refseq": "AFP regulator 1; alpha-fetoprotein regulator 1; regulator of AFP; transcription factor ZHX2; zinc finger and homeodomain protein 2; zinc fingers and homeoboxes protein 2", "tax_id": 10116, "disease": "", "pathway": " (rno:314988)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12741956;17056598;17457373", "class_list": "", "function": "Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA. May play a role in retinal development where it regulates the composition of bipolar cell populations, by promoting differentiation of bipolar OFF-type cells. In the brain, may promote maintenance and suppress differentiation of neural progenitor cells in the developing cortex., [UniProtKB, UniProtKB, UniProtKB]; Upregulation of B7.1 with the downregulation of GLEPP1, Wilms' tumor gene (WT1), megalin, and vascular endothelial growth factor started early and persisted through the course of primary glomerular disease., [RefSeq, PubMed]; ZHX proteins 1, 2 and 3 are major transcriptional mediators of podocyte disease Erratum:[J Biol Chem. 2007 Apr 27;282(17):13140], [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "G3V6P3", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045665 negative regulation of neuron differentiation;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q80VX4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q80W98-1", "uniprot_id": "SGTB_RAT", "mass": 33488.0, "length": 304, "protein_name": "Small glutamine-rich tetratricopeptide repeat-containing protein beta", "gene_name": "Sgtb", "organism": "Rat", "refseq_name": "small glutamine-rich tetratricopeptide repeat-containing protein beta", "refseq_ac": "NP_853660", "gene_names_uniprotkb": "Sgtb; Sgt2", "gene_names_refseq": "Sgt2; Sgtb", "protein_names_uniprotkb": "Small glutamine-rich tetratricopeptide repeat-containing protein beta; Beta-SGT; Small glutamine-rich protein with tetratricopeptide repeats 2", "protein_names_refseq": "beta-SGT; small glutamine rich tetratricopeptide repeat containing beta; small glutamine-rich protein with tetratricopeptide repeats 2; small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta; small glutamine-rich tetratricopeptide repeat-containing protein beta", "tax_id": 10116, "disease": "", "pathway": " (rno:294708)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12878599;22673903;23820636", "class_list": "", "function": "Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity., [UniProtKB, PubMed, UniProtKB, UniProtKB]; Up-regulation of SGTB is associated with neuronal apoptosis in the rat neuroinflammation model., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0042802 identical protein binding;GO:0051087 protein-folding chaperone binding;GO:0030544 Hsp70 protein binding", "go_cellular_component": "GO:0016020 membrane;GO:0072380 TRC complex", "go_biological_process": "GO:0006620 post-translational protein targeting to endoplasmic reticulum membrane;GO:0051260 protein homooligomerization;GO:0051291 protein heterooligomerization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q80W98-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q80ZG5-1", "uniprot_id": "SLU7_RAT", "mass": 68337.0, "length": 586, "protein_name": "Pre-mRNA-splicing factor SLU7", "gene_name": "Slu7", "organism": "Rat", "refseq_name": "pre-mRNA-splicing factor SLU7", "refseq_ac": "NP_001094020", "gene_names_uniprotkb": "Slu7", "gene_names_refseq": "Slu7", "protein_names_uniprotkb": "Pre-mRNA-splicing factor SLU7", "protein_names_refseq": "SLU7 homolog, splicing factor; SLU7 splicing factor homolog; pre-mRNA-splicing factor SLU7; step II splicing factor SLU7", "tax_id": 10116, "disease": "", "pathway": " (rno:303057); (R-RNO-159236); (R-RNO-72163)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "15181151;22673903", "class_list": "", "function": "Required for pre-mRNA splicing as component of the spliceosome. Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6P6G1", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0030628 pre-mRNA 3'-splice site binding;GO:0000386 second spliceosomal transesterification activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0016607 nuclear speck;GO:0005681 spliceosomal complex", "go_biological_process": "GO:0000375 RNA splicing, via transesterification reactions;GO:0006886 intracellular protein transport;GO:0034605 cellular response to heat;GO:0000380 alternative mRNA splicing, via spliceosome;GO:0045292 mRNA cis splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q80ZG5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q810T5-1", "uniprot_id": "KAT7_RAT", "mass": 70514.0, "length": 612, "protein_name": "Histone acetyltransferase KAT7", "gene_name": "Kat7", "organism": "Rat", "refseq_name": "histone acetyltransferase KAT7 isoform 1", "refseq_ac": "NP_851595", "gene_names_uniprotkb": "Kat7; Hbo1; Myst2", "gene_names_refseq": "Kat7; Myst2", "protein_names_uniprotkb": "Histone acetyltransferase KAT7; 2.3.1.48; Histone acetyltransferase binding to ORC1; Lysine acetyltransferase 7; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2; MYST-2", "protein_names_refseq": "K (lysine) acetyltransferase 7; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2; MYST histone acetyltransferase 2; MYST protein 2; MYST-2; histone acetyltransferase KAT7 isoform 1; histone acetyltransferase KAT7; histone acetyltransferase MYST2; histone acetyltransferase binding to ORC1", "tax_id": 10116, "disease": "breast cancer (Disease Ontology:DOID:1612); androgen insensitivity syndrome (Disease Ontology:DOID:4674)", "pathway": " (rno:303470); (R-RNO-3214847)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15005629;22673903", "class_list": "", "function": "Alteration of histone acetyltransferase CREB-binding protein acetylation of high mobility group box protein(HMGB)-1 and -2 and truncated forms lacking C-terminal tails is regarded as a mechanism by which the acidic tail modulates some properties of HMGBs., [RefSeq, PubMed]; Catalytic subunit of histone acetyltransferase HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), thereby regulating various processes, such as gene transcription, protein ubiquitination, immune regulation, stem cell pluripotent and self-renewal maintenance and embryonic development. Some complexes also catalyze acetylation of histone H4 at 'Lys-5', 'Lys-8' and 'Lys-12' (H4K5ac, H4K8ac and H4K12ac, respectively), regulating DNA replication initiation, regulating DNA replication initiation. Specificity of the HBO1 complexes is determined by the scaffold subunit: complexes containing BRPF scaffold (BRPF1, BRD1/BRPF2 or BRPF3) direct KAT7/HBO1 specificity towards H3K14ac, while complexes containing JADE (JADE1, JADE2 and JADE3) scaffold direct KAT7/HBO1 specificity towards histone H4. H3K14ac promotes transcriptional elongation by facilitating the processivity of RNA polymerase II. Acts as a key regulator of hematopoiesis by forming a complex with BRD1/BRPF2, directing KAT7/HBO1 specificity towards H3K14ac and promoting erythroid differentiation (By similarity). H3K14ac is also required for T-cell development (By similarity). KAT7/HBO1-mediated acetylation facilitates two consecutive steps, licensing and activation, in DNA replication initiation: H3K14ac facilitates the activation of replication origins, and histone H4 acetylation (H4K5ac, H4K8ac and H4K12ac) facilitates chromatin loading of MCM complexes, promoting DNA replication licensing. Acts as a positive regulator of centromeric CENPA assembly: recruited to centromeres and mediates histone acetylation, thereby preventing centromere inactivation mediated by SUV39H1, possibly by increasing histone turnover/exchange. Involved in nucleotide excision repair: phosphorylation by ATR in response to ultraviolet irradiation promotes its localization to DNA damage sites, where it mediates histone acetylation to facilitate recruitment of XPC at the damaged DNA sites. Acts as an inhibitor of NF-kappa-B independently of its histone acetyltransferase activity (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 17, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q80YN5", "ec_number_list": "2.3.1.48;2.3.1.-;2.7.11.1;2.7.11.4;2.3.1.259;2.3.1.80", "go_molecular_function": "GO:0003688 DNA replication origin binding;GO:0043997 histone H4K12 acetyltransferase activity;GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0000775 chromosome, centromeric region;GO:0000785 chromatin", "go_biological_process": "GO:0001779 natural killer cell differentiation;GO:0030174 regulation of DNA-templated DNA replication initiation;GO:0072708 response to sorbitol;GO:2000278 regulation of DNA biosynthetic process;GO:2000819 regulation of nucleotide-excision repair", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q810T5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8CF97-1", "uniprot_id": "VCIP1_RAT", "mass": 134566.0, "length": 1221, "protein_name": "Deubiquitinating protein VCPIP1", "gene_name": "Vcpip1", "organism": "Rat", "refseq_name": "deubiquitinating protein VCPIP1", "refseq_ac": "NP_789827", "gene_names_uniprotkb": "Vcpip1; Vcip135", "gene_names_refseq": "Vcip135; Vcpip1", "protein_names_uniprotkb": "Deubiquitinating protein VCPIP1; 3.4.19.12; VCP/p47 complex-interacting 135-kDa protein; Valosin-containing protein p97/p47 complex-interacting protein 1; Valosin-containing protein p97/p47 complex-interacting protein p135", "protein_names_refseq": "VCP(p97)/p47-interacting protein; VCP/p47 complex-interacting 135-kDa protein; deubiquitinating protein VCIP135; deubiquitinating protein VCPIP1; valosin-containing protein (p97)/p47 complex-interacting protein 135; valosin-containing protein p97/p47 complex-interacting protein 1; valosin-containing protein p97/p47 complex-interacting protein p135", "tax_id": 10116, "disease": "progeria (Disease Ontology:DOID:3911)", "pathway": " (rno:286761); (R-RNO-5689896)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "12473691;12810701;15037600;15328197;17550236;20871144;21811234;22673903;29393594", "class_list": "", "function": "Deubiquitinating enzyme involved in DNA repair and reassembly of the Golgi apparatus and the endoplasmic reticulum following mitosis (PubMed:12473691, PubMed:15037600). Necessary for VCP-mediated reassembly of Golgi stacks after mitosis (PubMed:12473691, PubMed:15037600). Plays a role in VCP-mediated formation of transitional endoplasmic reticulum (tER) (PubMed:12473691, PubMed:15037600). Mediates dissociation of the ternary complex containing STX5A, NSFL1C and VCP (PubMed:12473691, PubMed:15037600). Also involved in DNA repair following phosphorylation by ATM or ATR: acts by catalyzing deubiquitination of SPRTN, thereby promoting SPRTN recruitment to chromatin and subsequent proteolytic cleavage of covalent DNA-protein cross-links (DPCs) (By similarity). Hydrolyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitin chains (By similarity)., [UniProtKB, PubMed, PubMed, UniProtKB]; Electrical stimulation increased valosin-containing protein (VCP) expression and decreased cleaved caspase-12 expression in denervated muscles., [RefSeq, PubMed]; Expression is ignificant in the prognosis of esophageal squamous cell carcinoma, [RefSeq, PubMed]; Findings clearly reveal that native CYPs 3A undergo UPD and implicate a role for p97 in this process., [RefSeq, PubMed]; P47 localizes to the nucleus during interphase and is phosphorylated on Serine-140 by Cdc2 at mitosis. Phosphorylated p47 does not bind to Golgi membranes., [RefSeq, PubMed]; P97-p47-mediated reassembly of Golgi cisternae requires ubiquitin, but is not dependent on proteasome-mediated proteolysis. Erratum:[J Cell Biol. 2004 Aug 2;166(3):433. Wang, Yangzhuang [corrected to Wang, Yanzhuang]], [RefSeq, PubMed]; VCIP135 is required for golgi and endoplasmic reticulum assembly., [RefSeq, PubMed]; WAC is hence thought to function in p97/p47-mediated Golgi membrane fusion by activating the deubiquitinating function of VCIP135. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q7TNK5", "ec_number_list": "2.7.11.22;2.7.11.23;3.4.19.12", "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0045202 synapse", "go_biological_process": "GO:1905634 regulation of protein localization to chromatin;GO:0006508 proteolysis;GO:0016579 protein deubiquitination;GO:0006974 DNA damage response;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q8CF97-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8CFD0-1", "uniprot_id": "SFXN5_RAT", "mass": 37304.0, "length": 342, "protein_name": "Sideroflexin-5", "gene_name": "Sfxn5", "organism": "Rat", "refseq_name": "sideroflexin-5", "refseq_ac": "NP_695210", "gene_names_uniprotkb": "Sfxn5", "gene_names_refseq": "BBG-TCC; SLC64A5; Sfxn5", "protein_names_uniprotkb": "Sideroflexin-5; Tricarboxylate carrier BBG-TCC", "protein_names_refseq": "sideroflexin-5; solute carrier family 64 member 5; tricarboxylate carrier BBG-TCC", "tax_id": 10116, "disease": "", "pathway": " (rno:261737)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12150972;38843836", "class_list": "", "function": "Identification and functional characterization and possible role in biosynthesis and bioenergetics in the brain, [RefSeq, PubMed]; Mitochondrial amino-acid transporter (By similarity). Transports citrate (PubMed:12150972). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity) (PubMed:12150972). In brown adipose tissue, plays a role in the regulation of UCP1-dependent thermogenesis probably by supporting mitochondrial glycerol-3-phosphate utilization (By similarity)., [UniProtKB, PubMed, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015137 citrate transmembrane transporter activity;GO:0015075 monoatomic ion transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0006865 amino acid transport;GO:0015746 citrate transport;GO:0120162 positive regulation of cold-induced thermogenesis;GO:1990542 mitochondrial transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q8CFD0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8CGX0-1", "uniprot_id": "IF2B1_RAT", "mass": 63437.0, "length": 577, "protein_name": "Insulin-like growth factor 2 mRNA-binding protein 1", "gene_name": "Igf2bp1", "organism": "Rat", "refseq_name": "insulin-like growth factor 2 mRNA-binding protein 1", "refseq_ac": "NP_783184", "gene_names_uniprotkb": "Igf2bp1; Imp1; Vickz1", "gene_names_refseq": "Igf2bp1; Imp1; ZBP1", "protein_names_uniprotkb": "Insulin-like growth factor 2 mRNA-binding protein 1; B-actin zipcode-binding protein 1; IGF-II mRNA-binding protein 1; IGF2 mRNA-binding protein 1; IMP-1; VICKZ family member 1; ZBP1; rZBP-1", "protein_names_refseq": "B-actin zipcode-binding protein 1; IGF-II mRNA-binding protein 1; IGF2 mRNA-binding protein 1; IMP-1; VICKZ family member 1; insulin-like growth factor 2 mRNA-binding protein 1; insulin-like growth factor 2, binding protein 1; rZBP-1; zipcode-binding protein-1", "tax_id": 10116, "disease": "acquired metabolic disease (Disease Ontology:DOID:0060158)", "pathway": " (rno:303477)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "12716932;14614102;21471362;21964071;23069990;23897586;32918374;38563050;9178888", "class_list": "", "function": "Data support a role for SMN in the regulation of mRNA localization and axonal transport through its interaction with mRNA-binding proteins such as IMP1, [RefSeq, PubMed]; Inhibition of IGF2BP1 attenuates the progression of endometriosis through PTBP1., [RefSeq, PubMed]; RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Preferentially binds to N6-methyladenosine (m6A)-containing mRNAs and increases their stability (By similarity). During neuronal development, key regulator of neurite outgrowth, growth cone guidance and neuronal cell migration, presumably through the spatiotemporal fine tuning of protein synthesis, such as that of beta-actin/ACTB (By similarity). May regulate mRNA transport to activated synapses (By similarity). Binds to the 3'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells (By similarity). Binds to the oncofetal H19 transcript and to the neuron-specific TAU mRNA and regulates their localization (By similarity). Binds to and stabilizes BTRC/FBW1A mRNA (By similarity). Binds to the adenine-rich autoregulatory sequence (ARS) located in PABPC1 mRNA and represses its translation. PABPC1 mRNA-binding is stimulated by PABPC1 protein. Prevents BTRC/FBW1A mRNA degradation by disrupting microRNA-dependent interaction with AGO2 (By similarity). During cellular stress, such as oxidative stress or heat shock, stabilizes target mRNAs that are recruited to stress granules, including CD44, IGF2, MAPK4, MYC, PTEN, RAPGEF2 and RPS6KA5 transcripts (By similarity). Binds to the 3'-UTR of IGF2 mRNA by a mechanism of cooperative and sequential dimerization and regulates IGF2 mRNA subcellular localization and translation. Binds to MYC mRNA, in the coding region instability determinant (CRD) of the open reading frame (ORF), hence prevents MYC cleavage by endonucleases and possibly microRNA targeting to MYC-CRD (By similarity). Binding to MYC mRNA is enhanced by m6A-modification of the CRD (By similarity). Binds to and stabilizes ABCB1/MDR-1 mRNA (By similarity). During interstinal wound repair, interacts with and stabilizes PTGS2 transcript. PTGS2 mRNA stabilization may be crucial for colonic mucosal wound healing (By similarity). Interacts with GAP43 transcript and transports it to axons. Regulates localized ACTB mRNA translation, a crucial process for cell polarity, cell migration and neurite outgrowth. Co-transcriptionally associates with the ACTB mRNA in the nucleus. This binding involves a conserved 54-nucleotide element in the ACTB mRNA 3'-UTR, known as the 'zipcode'. The RNP thus formed is exported to the cytoplasm, binds to a motor protein and is transported along the cytoskeleton to the cell periphery. During transport, prevents ACTB mRNA from being translated into protein. When the RNP complex reaches its destination near the plasma membrane, IGF2BP1 is phosphorylated. This releases the mRNA, allowing ribosomal 40S and 60S subunits to assemble and initiate ACTB protein synthesis. Monomeric ACTB then assembles into the subcortical actin cytoskeleton. Plays a direct role in the transport and translation of transcripts required for axonal regeneration in adult sensory neurons., [UniProtKB, PubMed, PubMed, PubMed, PubMed, UniProtKB]; ZBP1 is required for the localization of beta-actin mRNA to dendrites of hippocampal neurons, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B1WBP3", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0003729 mRNA binding;GO:0003730 mRNA 3'-UTR binding;GO:0045182 translation regulator activity;GO:0048027 mRNA 5'-UTR binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0030027 lamellipodium;GO:0030424 axon", "go_biological_process": "GO:0010610 regulation of mRNA stability involved in response to stress;GO:0022013 pallium cell proliferation in forebrain;GO:0070934 CRD-mediated mRNA stabilization;GO:2000767 positive regulation of cytoplasmic translation;GO:0007399 nervous system development", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q8CGX0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8CHN6-1", "uniprot_id": "SGPL1_RAT", "mass": 63758.0, "length": 568, "protein_name": "Sphingosine-1-phosphate lyase 1", "gene_name": "Sgpl1", "organism": "Rat", "refseq_name": "sphingosine-1-phosphate lyase 1", "refseq_ac": "NP_775139", "gene_names_uniprotkb": "Sgpl1; Spl", "gene_names_refseq": "S1PL; Sgpl1; Spgl1; spl", "protein_names_uniprotkb": "Sphingosine-1-phosphate lyase 1; 4.1.2.27; S1PL; SP-lyase 1; SPL 1; SPL; Sphingosine-1-phosphate aldolase", "protein_names_refseq": "SP-lyase 1; SPL 1; sphingosine phosphate lyase 1; sphingosine-1-phosphate aldolase; sphingosine-1-phosphate lyase 1", "tax_id": 10116, "disease": "RENI syndrome (Disease Ontology:DOID:0080265); Charcot-Marie-Tooth disease (Disease Ontology:DOID:10595); nephrotic syndrome (Disease Ontology:DOID:1184); obesity (Disease Ontology:DOID:9970)", "pathway": " (rno:286896); (R-RNO-9845614)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "25630683;28165339;29070677;29393594;38843836", "class_list": "", "function": "Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis (By similarity). Required for global lipid homeostasis in liver and cholesterol homeostasis in fibroblasts. Involved in the regulation of pro-inflammatory response and neutrophil trafficking. Modulates neuronal autophagy via phosphoethanolamine production which regulates accumulation of aggregate-prone proteins such as APP (By similarity). Seems to play a role in establishing neuronal contact sites and axonal maintenance (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency, [RefSeq, PubMed]; Studied pathological alterations associated with only partially reduced activity of S1P lyase (as may be encountered upon pharmacological inhibition)., [RefSeq, PubMed]; The relatively low endogenous Spl expression level in insulin-secreting cells contributes to their extraordinary vulnerability to proinflammatory cytokine toxicity, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "4.1.2.27", "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0008117 sphinganine-1-phosphate aldolase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0016020 membrane", "go_biological_process": "GO:0008210 estrogen metabolic process;GO:0030149 sphingolipid catabolic process;GO:0001570 vasculogenesis;GO:0006631 fatty acid metabolic process;GO:0007283 spermatogenesis", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q8CHN6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8CJ99-1", "uniprot_id": "SCLT1_RAT", "mass": 80329.0, "length": 688, "protein_name": "Sodium channel and clathrin linker 1", "gene_name": "Sclt1", "organism": "Rat", "refseq_name": "sodium channel and clathrin linker 1", "refseq_ac": "NP_714962", "gene_names_uniprotkb": "Sclt1; Sap1", "gene_names_refseq": "CAP-1A; Sap1; Sclt1", "protein_names_uniprotkb": "Sodium channel and clathrin linker 1; CAP-1A; Clathrin-associated protein 1A; Sodium channel Nav1.8-binding protein; Sodium channel-associated protein 1", "protein_names_refseq": "clathrin-associated protein 1A; sodium channel Nav1.8-binding protein; sodium channel and clathrin linker 1; sodium channel-associated protein 1", "tax_id": 10116, "disease": "ciliopathy (Disease Ontology:DOID:0060340); autosomal recessive polycystic kidney disease (Disease Ontology:DOID:0110861)", "pathway": " (rno:266809); (R-RNO-5620912)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15797711;21586605", "class_list": "", "function": "Adapter protein that links SCN10A to clathrin. Regulates SCN10A channel activity, possibly by promoting channel internalization., [UniProtKB, PubMed]; Coexpression of beta-subunits of NaV1.8 strongly influences the affinity of the muO-conotoxin MrVIB conopeptide for the channel., [RefSeq, PubMed]; SAP-1 is the first example of an adapter protein that links clathrin and a sodium channel and may regulate Na(v)1.8 channel density at the cell surface., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8CJ83;Q8CJ84;Q8CJ98", "ec_number_list": "", "go_molecular_function": "GO:0017080 sodium channel regulator activity;GO:0030276 clathrin binding", "go_cellular_component": "GO:0005813 centrosome;GO:0005814 centriole;GO:0036064 ciliary basal body;GO:0097539 ciliary transition fiber;GO:0071439 clathrin complex", "go_biological_process": "GO:0060271 cilium assembly;GO:0045162 clustering of voltage-gated sodium channels", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q8CJ99-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8CJD3-1", "uniprot_id": "ZG16_RAT", "mass": 18213.0, "length": 167, "protein_name": "Zymogen granule membrane protein 16", "gene_name": "Zg16", "organism": "Rat", "refseq_name": "zymogen granule membrane protein 16 precursor", "refseq_ac": "NP_599236", "gene_names_uniprotkb": "Zg16", "gene_names_refseq": "Zg-16p; Zg16p; Zg16", "protein_names_uniprotkb": "Zymogen granule membrane protein 16; Secretory lectin ZG16; Zymogen granule protein 16", "protein_names_refseq": "secretory lectin ZG16; zymogen granule membrane protein 16 precursor; zymogen granule membrane protein 16", "tax_id": 10116, "disease": "", "pathway": " (rno:171449)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10099930;21948871;7720729", "class_list": "", "function": "May play a role in protein trafficking. May act as a linker molecule between the submembranous matrix on the luminal side of zymogen granule membrane (ZGM) and aggregated secretory proteins during granule formation in the TGN., [UniProtKB, PubMed]; ZG16p, an animal homolog of beta-prism fold plant lectins, interacts with heparan sulfate proteoglycans in pancreatic zymogen granules., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q63680", "ec_number_list": "", "go_molecular_function": "GO:0042834 peptidoglycan binding;GO:0030246 carbohydrate binding", "go_cellular_component": "GO:0070701 mucus layer;GO:0005615 extracellular space;GO:0005796 Golgi lumen;GO:0042589 zymogen granule membrane", "go_biological_process": "GO:0015031 protein transport;GO:0050830 defense response to Gram-positive bacterium;GO:0052373 suppression of symbiont entry into host", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q8CJD3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8R496-1", "uniprot_id": "SPDYA_RAT", "mass": 36223.0, "length": 312, "protein_name": "Speedy protein A", "gene_name": "Spdya", "organism": "Rat", "refseq_name": "speedy protein A", "refseq_ac": "NP_620210", "gene_names_uniprotkb": "Spdya; Spdy1", "gene_names_refseq": "Gs4; Lm23; Spdy1; Spdya; Spy1", "protein_names_uniprotkb": "Speedy protein A; GS4; RINGO A; Rapid inducer of G2/M progression in oocytes A; Speedy-1; Spy1", "protein_names_refseq": "RINGO A; rapid inducer of G2/M progression in oocytes A; speedy homolog 1; speedy homolog A; speedy protein A; speedy-1; spermatogenesis related protein Gs4", "tax_id": 10116, "disease": "", "pathway": " (rno:192209)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "17376406;19082704;22751172;23129232;23685908", "class_list": "", "function": "In the hippocampus, SpeedyRINGO acts as a savior for neurons that are under apoptosis. Erratum:[J Alzheimers Dis. 2016 Jul 13;53(2):743. doi: 10.3233/JAD-169003. PMID: 27434285], [RefSeq, PubMed]; LM23 played a protective role in H2O2-induced apoptosis of 293T cells, mediated at least in part through the Akt/PI3K signal pathway; these results provide new insights into the role of LM23 in the development of the testes and spermatogenesis., [RefSeq, PubMed]; Peripheral nerve injury induced an up-regulation of Spy1 in lumbar spinal cord, which was associated with glial proliferation., [RefSeq, PubMed]; Regulates the G1/S phase transition of the cell cycle by binding and activating CDK1 and CDK2. Contributes to CDK2 activation without promoting CDK2 phosphorylation, by inducing a conformation change of the CDK2 T-loop that obstructs the substrate-binding cleft prior to kinase activation. Interferes with CDKN1B-mediated inhibition of CDK2. Mediates cell survival during the DNA damage process through activation of CDK2., [UniProtKB, UniProtKB, UniProtKB]; Spy1 participated in the pathological process response to sciatic nerve injury and may be associated with Schwann cells proliferation and axons regeneration., [RefSeq, PubMed]; Testis-specific gene LM23 identified & characterized from rat type A spermatogonia, pachytene spermatocytes, & round spermatids., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q68G34", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding;GO:0030295 protein kinase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005654 nucleoplasm;GO:0070971 endoplasmic reticulum exit site;GO:0001741 XY body", "go_biological_process": "GO:0007283 spermatogenesis;GO:0008284 positive regulation of cell population proliferation;GO:0010628 positive regulation of gene expression;GO:0045860 positive regulation of protein kinase activity;GO:0006974 DNA damage response", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q8R496-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8R4T2-1", "uniprot_id": "SIAH2_RAT", "mass": 34700.0, "length": 325, "protein_name": "E3 ubiquitin-protein ligase SIAH2", "gene_name": "Siah2", "organism": "Rat", "refseq_name": "E3 ubiquitin-protein ligase SIAH2", "refseq_ac": "NP_604452", "gene_names_uniprotkb": "Siah2", "gene_names_refseq": "Siah2", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase SIAH2; 2.3.2.27; RING-type E3 ubiquitin transferase SIAH2; Seven in absentia homolog 2; Siah-2", "protein_names_refseq": "E3 ubiquitin-protein ligase SIAH2; RING-type E3 ubiquitin transferase SIAH2; seven in absentia 2; seven in absentia homolog 2; siah-2", "tax_id": 10116, "disease": "", "pathway": " (rno:140593); (R-RNO-5689880); (R-RNO-983168)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "11786535;15064394;19224863", "class_list": "", "function": "E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:11786535). E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates (PubMed:11786535). Mediates E3 ubiquitin ligase activity either through direct binding to substrates or by functioning as the essential RING domain subunit of larger E3 complexes (By similarity). Mediates ubiquitination and proteasomal degradation of DYRK2 in response to hypoxia (By similarity). Promotes monoubiquitination of SNCA (By similarity). Triggers the ubiquitin-mediated degradation of many substrates, including proteins involved in transcription regulation (GPS2, POU2AF1, PML, NCOR1), a cell surface receptor (DCC), an antiapoptotic protein (BAG1), and a protein involved in synaptic vesicle function in neurons (SYP) (PubMed:11786535). It is thereby involved in apoptosis, tumor suppression, cell cycle, transcription and signaling processes (By similarity). Has some overlapping function with SIAH1 (By similarity). Triggers the ubiquitin-mediated degradation of TRAF2, whereas SIAH1 does not (By similarity). Regulates cellular clock function via ubiquitination of circadian transcriptional repressors NR1D1 and NR1D2 leading to their proteasomal degradation. Plays an important role in mediating the rhythmic degradation/clearance of NR1D1 and NR1D2 contributing to their circadian profile of protein abundance (By similarity). Mediates ubiquitination and degradation of EGLN2 and EGLN3 in response to the unfolded protein response (UPR), leading to their degradation and subsequent stabilization of ATF4 (By similarity). Also part of the Wnt signaling pathway in which it mediates the Wnt-induced ubiquitin-mediated proteasomal degradation of AXIN1 (By similarity)., [UniProtKB, UniProtKB, PubMed, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q920M8", "ec_number_list": "2.3.2.26;2.3.2.32;2.3.2.31;2.3.2.23;2.3.2.27;2.3.2.34;2.3.2.24;2.3.2.-;2.3.2.25;3.4.19.12", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0031624 ubiquitin conjugating enzyme binding;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005769 early endosome;GO:0005829 cytosol;GO:0043025 neuronal cell body", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0006915 apoptotic process;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q8R4T2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8R5K5-1", "uniprot_id": "UTP11_RAT", "mass": 30499.0, "length": 253, "protein_name": "Probable U3 small nucleolar RNA-associated protein 11", "gene_name": "Utp11", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Utp11; Utp11l", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable U3 small nucleolar RNA-associated protein 11; U3 snoRNA-associated protein 11; UTP11-like protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-6791226)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "11860508", "class_list": "", "function": "Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in nucleolar processing of pre-18S ribosomal RNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0032040 small-subunit processome", "go_biological_process": "GO:0007399 nervous system development;GO:0043065 positive regulation of apoptotic process;GO:0006364 rRNA processing;GO:0042274 ribosomal small subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8R5K5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8R5M3-1", "uniprot_id": "LRC15_RAT", "mass": 64128.0, "length": 578, "protein_name": "Leucine-rich repeat-containing protein 15", "gene_name": "Lrrc15", "organism": "Rat", "refseq_name": "leucine-rich repeat-containing protein 15 precursor", "refseq_ac": "NP_659551", "gene_names_uniprotkb": "Lrrc15; Lib", "gene_names_refseq": "Lib; Lrrc15", "protein_names_uniprotkb": "Leucine-rich repeat-containing protein 15; Leucine-rich repeat protein induced by amyloid-beta; rLib", "protein_names_refseq": "leucine-rich repeat protein induced by amyloid-beta; leucine-rich repeat protein induced by beta-amyloid; leucine-rich repeat-containing protein 15 precursor; leucine-rich repeat-containing protein 15; rLib", "tax_id": 10116, "disease": "", "pathway": " (rno:246296)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "11785964", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0099530 G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential;GO:0004930 G protein-coupled receptor activity;GO:0005518 collagen binding;GO:0043236 laminin binding;GO:0030331 nuclear estrogen receptor binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005634 nucleus;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0014069 postsynaptic density", "go_biological_process": "GO:0007206 phospholipase C-activating G protein-coupled glutamate receptor signaling pathway;GO:0007186 G protein-coupled receptor signaling pathway;GO:0007626 locomotory behavior;GO:0019722 calcium-mediated signaling;GO:0030335 positive regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8R5M3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q91WW1-1", "uniprot_id": "UCN2_RAT", "mass": 11922.0, "length": 109, "protein_name": "Urocortin-2", "gene_name": "Col7a1; Ucn2", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Col7a1; Ucn2; Ucn2", "gene_names_refseq": "", "protein_names_uniprotkb": "Urocortin-2; Ucn II; Urocortin II", "protein_names_refseq": "", "tax_id": 10116, "disease": "colitis (Disease Ontology:DOID:0060180); recessive dystrophic epidermolysis bullosa (Disease Ontology:DOID:0060642); nonsyndromic congenital nail disorder 8 (Disease Ontology:DOID:0080086); autosomal dominant dystrophic epidermolysis bullosa (Disease Ontology:DOID:0080224); pretibial dystrophic epidermolysis bullosa (Disease Ontology:DOID:0080988); transient bullous dermolysis of the newborn (Disease Ontology:DOID:0111345); epidermolysis bullosa with congenital localized absence of skin and deformity of nails (Disease Ontology:DOID:0111347); hypertension (Disease Ontology:DOID:10763); atherosclerosis (Disease Ontology:DOID:1936); epidermolysis bullosa dystrophica (Disease Ontology:DOID:4959); congestive heart failure (Disease Ontology:DOID:6000)", "pathway": " (rno:301012); (R-RNO-1442490); (R-RNO-1566977); (R-RNO-1650814); (R-RNO-204005); (R-RNO-216083); (R-RNO-2214320); (R-RNO-373080); (R-RNO-5694530); (R-RNO-8948216)", "pathway_count": 10, "publication_count": 1, "publication_id_list": "19334530", "class_list": "", "function": "Hormone that plays a central role in whole body adaptation to stress. Released by the hypothalamus primarily in response to physical or psychological stress and acts by binding to CRH receptor CRHR2 (By similarity). UCN2-dependent signaling regulates cardiovascular function, promotes skeletal muscle hypertrophy and manage energy balance and acts as an anorexigenic agent (By similarity). In contrast to CRH and UCN, does not activate the hypothalamus-pituitary-adrenal axis to promote corticotropin hormone (ACTH) production (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen., [UniProtKB, UniProtKB]; Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 11, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051429 corticotropin-releasing hormone receptor binding;GO:0001664 G protein-coupled receptor binding;GO:0042562 hormone binding;GO:0005179 hormone activity;GO:0051431 corticotropin-releasing hormone receptor 2 binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005576 extracellular region;GO:0005604 basement membrane", "go_biological_process": "GO:0046882 negative regulation of follicle-stimulating hormone secretion;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0010629 negative regulation of gene expression;GO:0071456 cellular response to hypoxia;GO:0009755 hormone-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q91WW1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q91ZW1-1", "uniprot_id": "TFAM_RAT", "mass": 28187.0, "length": 244, "protein_name": "Transcription factor A, mitochondrial", "gene_name": "Tfam", "organism": "Rat", "refseq_name": "transcription factor A, mitochondrial precursor", "refseq_ac": "NP_112616", "gene_names_uniprotkb": "Tfam", "gene_names_refseq": "Mttfa; Tfam", "protein_names_uniprotkb": "Transcription factor A, mitochondrial; mtTFA", "protein_names_refseq": "transcription factor A, mitochondrial precursor", "tax_id": 10116, "disease": "mitochondrial DNA depletion syndrome 15 (Disease Ontology:DOID:0080337); Alzheimer's disease (Disease Ontology:DOID:10652); Huntington's disease (Disease Ontology:DOID:12858); Kearns-Sayre syndrome (Disease Ontology:DOID:12934); Parkinson's disease (Disease Ontology:DOID:14330); status epilepticus (Disease Ontology:DOID:1824); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); obesity (Disease Ontology:DOID:9970)", "pathway": " (rno:83474); (R-RNO-163282); (R-RNO-9837999)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "10902920;11943465;12198131;30563025;31314594;31942725", "class_list": "", "function": "Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Component of the mitochondrial transcription initiation complex, composed at least of TFB2M, TFAM and POLRMT that is required for basal transcription of mitochondrial DNA. In this complex, TFAM recruits POLRMT to a specific promoter whereas TFB2M induces structural changes in POLRMT to enable promoter opening and trapping of the DNA non-template strand. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA (By similarity)., [UniProtKB, UniProtKB]; May also function as a transcriptional activator or may have a structural role in the compaction of nuclear DNA during spermatogenesis., [UniProtKB, UniProtKB]; NRF1-enhanced miR-4458 alleviates cardiac hypertrophy through releasing TTP-inhibited TFAM., [RefSeq, PubMed]; Reduced O2 consumption was observed with Tfam knockdown., [RefSeq, PubMed]; We also assessed mitochondrial DNA (mtDNA) content, citrate synthase activity, oxidative lesions to protein and mtDNA (i.e., carbonyls and the abundance of mtDNA(4834) deletion), and the mitochondrial transcription factor A (TFAM) binding to specific mtDNA regions. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9WTM7", "ec_number_list": "", "go_molecular_function": "GO:0001018 mitochondrial promoter sequence-specific DNA binding;GO:0003682 chromatin binding;GO:0031072 heat shock protein binding;GO:0043565 sequence-specific DNA binding;GO:0001223 transcription coactivator binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0005829 cytosol;GO:0042645 mitochondrial nucleoid", "go_biological_process": "GO:0033108 mitochondrial respiratory chain complex assembly;GO:0006391 transcription initiation at mitochondrial promoter;GO:0007584 response to nutrient;GO:0001666 response to hypoxia;GO:0006390 mitochondrial transcription", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q91ZW1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q920H8-1", "uniprot_id": "HEPH_RAT", "mass": 129593.0, "length": 1157, "protein_name": "Hephaestin", "gene_name": "Heph", "organism": "Rat", "refseq_name": "hephaestin precursor", "refseq_ac": "NP_579838", "gene_names_uniprotkb": "Heph", "gene_names_refseq": "Heph", "protein_names_uniprotkb": "Hephaestin; 1.16.3.1", "protein_names_refseq": "hephaestin precursor", "tax_id": 10116, "disease": "glaucoma (Disease Ontology:DOID:1686)", "pathway": " (rno:117240); (R-RNO-425410); (R-RNO-917937)", "pathway_count": 3, "publication_count": 8, "publication_id_list": "11557513;11891802;17383861;17516501;17561842;22350470;22673903;25318588", "class_list": "", "function": "Cellular locations identified by immunofluorescence, [RefSeq, PubMed]; Cytosolic Heph increased upon iron-deprivation but more important, decreased significantly upon copper-deprivation, mimicking the response of membrane-bound Heph., [RefSeq, PubMed]; Development and iron-dependent expression of Heph in different brain regions is reported., [RefSeq, PubMed]; Hepcidin or enterocyte iron levels may be involved in the regulation of the age-dependent expression in the duodenum., [RefSeq, PubMed]; Hephaestin might have a role in heart iron homeostasis., [RefSeq, PubMed]; Plasma membrane ferroxidase that mediates the extracellular conversion of ferrous/Fe(2+) iron into its ferric/Fe(3+) form. Couples ferroportin which specifically exports ferrous/Fe(2+) iron from cells to transferrin that only binds and shuttles extracellular ferric/Fe(3+) iron throughout the body. By helping iron transfer from cells to blood mainly contributes to dietary iron absorption by the intestinal epithelium and more generally regulates iron levels in the body., [UniProtKB, UniProtKB]; These results show for the first time that FP1 and HP co-localize in the rat brain, and suggest that decreased expression of these transporters in the SN can account for the increased iron levels., [RefSeq, PubMed]", "predicted_glycosites": 9, "predicted_n_glycosites": 8, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.16.3.1;1.11.1.27;1.11.1.9;1.16.3.4", "go_molecular_function": "GO:0005507 copper ion binding;GO:0004322 ferroxidase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0006826 iron ion transport;GO:0060586 multicellular organismal-level iron ion homeostasis;GO:0160179 intestinal iron absorption;GO:1904040 positive regulation of iron export across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q920H8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q920L2-1", "uniprot_id": "SDHA_RAT", "mass": 71615.0, "length": 656, "protein_name": "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "gene_name": "Sdha", "organism": "Rat", "refseq_name": "succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial precursor", "refseq_ac": "NP_569112", "gene_names_uniprotkb": "Sdha", "gene_names_refseq": "Sdha", "protein_names_uniprotkb": "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; 1.1.5.-; 1.3.5.1; Flavoprotein subunit of complex II; Fp; Malate dehydrogenase [quinone] flavoprotein subunit", "protein_names_refseq": "flavoprotein subunit of complex II; fp; malate dehydrogenase [quinone] flavoprotein subunit; succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial precursor; succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; succinate dehydrogenase complex, subunit A, flavoprotein (Fp)", "tax_id": 10116, "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); pheochromocytoma (Disease Ontology:DOID:0050771); paraganglioma (Disease Ontology:DOID:0050773); mitochondrial complex II deficiency (Disease Ontology:DOID:0060537); pheochromocytoma/paraganglioma syndrome 5 (Disease Ontology:DOID:0061220); dilated cardiomyopathy 1GG (Disease Ontology:DOID:0110435); leukodystrophy (Disease Ontology:DOID:10579); neurodegenerative disease (Disease Ontology:DOID:1289); Parkinson's disease (Disease Ontology:DOID:14330); Leigh disease (Disease Ontology:DOID:3652); pituitary adenoma (Disease Ontology:DOID:3829); lung non-small cell carcinoma (Disease Ontology:DOID:3908); gastrointestinal stromal tumor (Disease Ontology:DOID:9253)", "pathway": " (rno:157074); (R-RNO-71403); (R-RNO-9854311)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "25483313;26446791;27213235;34502162;36005845", "class_list": "", "function": "Data suggest activation/acetylation of Sdha in skeletal muscle can be regulated by diet; maternal low-protein leads to inactivation of Sdha; postnatal high-fat leads to further inactivation of Sdha; this increases susceptibility to type 2 diabetes., [RefSeq, PubMed]; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (By similarity). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate. Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate (By similarity). Can act as a tumor suppressor (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; [Molecular and biochemical studies of succinate dehydrogenase in rat liver under conditions of alloxan diabetes].', trans 'Molekuliarnye i biokhimicheskie issledovaniia suktsinatdegidrogenazy v pecheni krys v usloviiakh alloksanovogo diabeta., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 5, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 5, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 5, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 13, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.3.5.1;1.1.5.-", "go_molecular_function": "GO:0009055 electron transfer activity;GO:0050660 flavin adenine dinucleotide binding;GO:0008177 succinate dehydrogenase (quinone) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005759 mitochondrial matrix;GO:0045273 respiratory chain complex II (succinate dehydrogenase)", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0007399 nervous system development;GO:0042776 proton motive force-driven mitochondrial ATP synthesis;GO:0022904 respiratory electron transport chain;GO:0006105 succinate metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q920L2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q923U9-1", "uniprot_id": "S40A1_RAT", "mass": 62616.0, "length": 570, "protein_name": "Ferroportin", "gene_name": "Slc40a1", "organism": "Rat", "refseq_name": "ferroportin", "refseq_ac": "NP_579849", "gene_names_uniprotkb": "Slc40a1; Fpn1; Fpt1", "gene_names_refseq": "Fpn1; Slc11a3; Slc39a1; Slc40a1", "protein_names_uniprotkb": "Ferroportin; CAR1; Cell adhesion regulator; Ferroportin-1; Solute carrier family 40 member 1", "protein_names_refseq": "CAR1; cell adhesion regulator; ferroportin-1; ferroportin; solute carrier family 39 (iron-regulated transporter), member 1; solute carrier family 40 (iron-regulated transporter), member 1", "tax_id": 10116, "disease": "idiopathic pulmonary fibrosis (Disease Ontology:DOID:0050156); hemochromatosis type 4 (Disease Ontology:DOID:0111028); iron deficiency anemia (Disease Ontology:DOID:11758); Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (rno:170840); (R-RNO-425410); (R-RNO-917937)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "12091366;28273797;29757912;30027341;34748769", "class_list": "", "function": "Ata thereby indicate that heat stroke can decrease learning ability and memory in rats. The mechanism may be related to changes of iron levels, as well as Fpn1 and hepcidin expression, in the hippocampus., [RefSeq, PubMed]; Data suggest that expression of ferroportin in intestinal mucosa can be regulated by dietary factors; here, partially hydrolyzed guar gum up-regulates expression of ferroportin in cecum mucosa in growing rats being treated for iron deficiency anemia with this probiotic; intestinal absorption of dietary iron appears to be up-regulated, as well. Publication Status: Online-Only, [RefSeq, PubMed]; Ferroportin-mediated ferroptosis involved in new-onset atrial fibrillation with LPS-induced endotoxemia., [RefSeq, PubMed]; May be involved in iron transport and iron homeostasis., [UniProtKB, UniProtKB]; The finding of a novel mutation (V162del) in ferroportin1 in an Australian family with autosomal dominant hemochromatosis; the mutation disrupts the function of the ferroportin1 protein, leading to impaired iron homeostasis and iron overload, [RefSeq, PubMed]; These data point towards a transcriptional induction of Fpn in response to changes in cellular iron levels. Erratum:[Mol Neurobiol. 2019 Apr;56(4):2375-2378. doi: 10.1007/s12035-018-1282-7. PMID: 30128649], [RefSeq, PubMed]; Transports Fe(2+) from the inside of a cell to the outside of the cell, playing a key role for maintaining systemic iron homeostasis (By similarity). Transports iron from intestinal, splenic, hepatic cells, macrophages and erythrocytes into the blood to provide iron to other tissues. Controls therefore dietary iron uptake, iron recycling by macrophages and erythrocytes, and release of iron stores in hepatocytes (By similarity). When iron is in excess in serum, circulating HAMP/hepcidin levels increase resulting in a degradation of SLC40A1, thus limiting the iron efflux to plasma (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "G3V6H7;Q9Z1C9", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0017046 peptide hormone binding;GO:0015093 ferrous iron transmembrane transporter activity;GO:0005381 iron ion transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane;GO:0008021 synaptic vesicle", "go_biological_process": "GO:0002260 lymphocyte homeostasis;GO:0034755 iron ion transmembrane transport;GO:0060345 spleen trabecula formation;GO:1903988 iron ion export across plasma membrane;GO:0043066 negative regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q923U9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q924V4-1", "uniprot_id": "S15A3_RAT", "mass": 64593.0, "length": 582, "protein_name": "Solute carrier family 15 member 3", "gene_name": "Slc15a3", "organism": "Rat", "refseq_name": "solute carrier family 15 member 3", "refseq_ac": "NP_647557", "gene_names_uniprotkb": "Slc15a3; Pht2", "gene_names_refseq": "Pht2; Slc15a3", "protein_names_uniprotkb": "Solute carrier family 15 member 3; Peptide transporter 3; Peptide/histidine transporter 2", "protein_names_refseq": "peptide transporter 3; peptide/histidine transporter 2; peptide/histidine transporter PHT2; solute carrier family 15 (oligopeptide transporter), member 3; solute carrier family 15 member 3", "tax_id": 10116, "disease": "", "pathway": " (rno:246239); (R-RNO-427975)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "11336635;19913073", "class_list": "", "function": "Proton-coupled amino-acid transporter that transports free histidine and certain di- and tripeptides, and is involved in innate immune response (PubMed:11336635). Preferably binds to short peptides with a basic residue at the first position and a hydrophobic residue at the second position (By similarity). Also able to transport carnosine (By similarity). Involved in the detection of microbial pathogens by toll-like receptors (TLRs) and NOD-like receptors (NLRs), probably by mediating transport of bacterial peptidoglycans across the endolysosomal membrane: catalyzes the transport of certain bacterial peptidoglycans, such as muramyl dipeptide (MDP), the NOD2 ligand (By similarity)., [UniProtKB, UniProtKB, PubMed, UniProtKB, UniProtKB, UniProtKB]; These findings represent the first evidence that peptide transport via SLC15a1, 2, 3, and 4 occurs in thyroid follicular cells., [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015293 symporter activity;GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity;GO:0071916 dipeptide transmembrane transporter activity;GO:0015647 peptidoglycan transmembrane transporter activity", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0010008 endosome membrane;GO:0016020 membrane", "go_biological_process": "GO:0015031 protein transport;GO:0045087 innate immune response;GO:0030163 protein catabolic process;GO:0140206 dipeptide import across plasma membrane;GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q924V4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q99MH3-1", "uniprot_id": "HEPC_RAT", "mass": 9286.0, "length": 84, "protein_name": "Hepcidin", "gene_name": "Hamp", "organism": "Rat", "refseq_name": "hepcidin precursor", "refseq_ac": "NP_445921", "gene_names_uniprotkb": "Hamp; Hepc", "gene_names_refseq": "Hamp; Hepc", "protein_names_uniprotkb": "Hepcidin", "protein_names_refseq": "hepcidin precursor", "tax_id": 10116, "disease": "metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); alcohol-associated liver disease (Disease Ontology:DOID:0070658); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); hemochromatosis type 2B (Disease Ontology:DOID:0111032); iron deficiency anemia (Disease Ontology:DOID:11758); primary biliary cholangitis (Disease Ontology:DOID:12236); beta thalassemia (Disease Ontology:DOID:12241); pure red-cell aplasia (Disease Ontology:DOID:1340); extrahepatic cholestasis (Disease Ontology:DOID:13619); hemochromatosis (Disease Ontology:DOID:2352); anemia (Disease Ontology:DOID:2355); middle cerebral artery infarction (Disease Ontology:DOID:3525); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); hepatocellular carcinoma (Disease Ontology:DOID:684); end stage renal disease (Disease Ontology:DOID:783); myocarditis (Disease Ontology:DOID:820)", "pathway": " (rno:84604)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "11113132;29757912;31839527;33544508;34143808", "class_list": "", "function": "Ata thereby indicate that heat stroke can decrease learning ability and memory in rats. The mechanism may be related to changes of iron levels, as well as Fpn1 and hepcidin expression, in the hippocampus., [RefSeq, PubMed]; Comparison of the effects of zinc oxide and zinc oxide nanoparticles on the expression of hepcidin gene in rat liver. Publication Status: Online-Only, [RefSeq, PubMed]; DNA methylation suppresses liver Hamp expression in response to iron deficiency after bariatric surgery., [RefSeq, PubMed]; Has strong antimicrobial activity against E.coli ML35P N.cinerea and weaker against S.epidermidis, S.aureus and group b streptococcus bacteria. Active against the fungus C.albicans. No activity against P.aeruginosa., [UniProtKB, UniProtKB]; Intestinal iron absorption is appropriately modulated to match physiological demand for iron in wild-type and iron-loaded Hamp (hepcidin) knockout rats during acute colitis. Publication Status: Online-Only, [RefSeq, PubMed]; Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin/SLC40A1, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 17, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0005179 hormone activity;GO:0005507 copper ion binding;GO:0097690 iron ion transmembrane transporter inhibitor activity;GO:0141108 transporter regulator activity", "go_cellular_component": "GO:0045179 apical cortex;GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0005634 nucleus;GO:0014704 intercalated disc", "go_biological_process": "GO:0043032 positive regulation of macrophage activation;GO:2000646 positive regulation of receptor catabolic process;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0010043 response to zinc ion;GO:0045471 response to ethanol", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q99MH3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q99NI4-1", "uniprot_id": "IPMK_RAT", "mass": 44410.0, "length": 396, "protein_name": "Inositol polyphosphate multikinase", "gene_name": "Ipmk", "organism": "Rat", "refseq_name": "inositol polyphosphate multikinase", "refseq_ac": "NP_599244", "gene_names_uniprotkb": "Ipmk; Impk; Ipk2", "gene_names_refseq": "Impk; Ipk2; Ipmk", "protein_names_uniprotkb": "Inositol polyphosphate multikinase; 2.7.1.140; 2.7.1.151; 2.7.1.153; Inositol 1,3,4,6-tetrakisphosphate 5-kinase", "protein_names_refseq": "inositol 1,3,4,6-tetrakisphosphate 5-kinase; inositol polyphosphate kinase 2; inositol polyphosphate multikinase", "tax_id": 10116, "disease": "", "pathway": " (rno:171458); (R-RNO-1855191)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "11226235;15528195;16123124;22940627", "class_list": "", "function": "IPK2 and IPK1 act as key determining steps in production of IP5 and IP6, respectively, [RefSeq, PubMed]; Inositol phosphate kinase with a broad substrate specificity. Phosphorylates inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) first to inositol 1,3,4,5-tetrakisphosphate and then to inositol 1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5) (PubMed:11226235, PubMed:15528195). Phosphorylates inositol 1,3,4,6-tetrakisphosphate (Ins(1,3,4,6)P4) (PubMed:15528195). Phosphorylates inositol 1,4,5,6-tetrakisphosphate (Ins(1,4,5,6)P4) (PubMed:15528195). Phosphorylates glycero-3-phospho-1D-myo-inositol 4,5-bisphosphate to glycero-3-phospho-1D-myo-inositol 3,4,5-trisphosphate (PubMed:16123124). Plays an important role in MLKL-mediated necroptosis via its role in the biosynthesis of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Binding of these highly phosphorylated inositol phosphates to MLKL mediates the release of an N-terminal auto-inhibitory region, leading to activation of the kinase. Essential for activated phospho-MLKL to oligomerize and localize to the cell membrane during necroptosis (By similarity). Required for normal embryonic development, probably via its role in the biosynthesis of inositol 1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5) and inositol hexakisphosphate (InsP6) (By similarity)., [UniProtKB, PubMed, PubMed, UniProtKB, UniProtKB, PubMed]; Translocation of IPMK to plasma membrane via docking Dvl3 is important for IPMK to access substrates and generate IP5, activating down-stream signaling., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.1.153;2.7.1.137;2.7.1.154;2.7.-.-;2.7.1.151;2.7.1.140", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity;GO:0046934 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity;GO:0000823 inositol-1,4,5-trisphosphate 6-kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0046488 phosphatidylinositol metabolic process;GO:0070266 necroptotic process;GO:0032957 inositol trisphosphate metabolic process;GO:0032958 inositol phosphate biosynthetic process;GO:0001841 neural tube formation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q99NI4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q99P67-1", "uniprot_id": "SOST_RAT", "mass": 23974.0, "length": 213, "protein_name": "Sclerostin", "gene_name": "Sost", "organism": "Rat", "refseq_name": "sclerostin precursor", "refseq_ac": "NP_085073", "gene_names_uniprotkb": "Sost", "gene_names_refseq": "Sost", "protein_names_uniprotkb": "Sclerostin", "protein_names_refseq": "sclerosteosis; sclerostin precursor", "tax_id": 10116, "disease": "sclerosteosis (Disease Ontology:DOID:0060251); sclerosteosis 1 (Disease Ontology:DOID:0060756); SOST-related sclerosing bone dysplasia (Disease Ontology:DOID:0080036); autosomal dominant craniodiaphyseal dysplasia (Disease Ontology:DOID:0080807)", "pathway": " (rno:80722); (R-RNO-3772470)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "11179006;15199066;15946907;30699436;31112281;31330917;32844318;33508832", "class_list": "", "function": "Beta-GP induced VSMC calcification by activating the Wnt/beta-catenin signaling pathway. Sclerostin and Lrp4 were involved in beta-GP-induced VSMC calcification and play an important role. GBE could alleviate VSMC calcification induced by beta-GP through inhibiting the Wnt/beta-catenin signaling pathway., [RefSeq, PubMed]; Changes in the intra- and peri-cellular sclerostin distribution in lacuno-canalicular system induced by mechanical unloading. Erratum:[J Bone Miner Metab. 2021 Mar;39(2):160-162. doi: 10.1007/s00774-020-01155-5. PMID: 33025107], [RefSeq, PubMed]; Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation., [UniProtKB]; Noggin and sclerostin form a mutually inhibitory complex that fine-tunes of BMP activity in bone homeostasis, [RefSeq, PubMed]; SOST regulation may play a role in mediating PTH action in bone, [RefSeq, PubMed]; Sclerostin as Regulatory Molecule in Vascular Media Calcification and the Bone-Vascular Axis. Publication Status: Online-Only, [RefSeq, PubMed]; The Possible Role of Sclerostin in the Pathogenesis of Tympanosclerosis., [RefSeq, PubMed]; The combination of ZOL and the osteoanabolic sclerostin antibody was more effective than either agent alone. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008201 heparin binding;GO:0030246 carbohydrate binding;GO:0036122 BMP binding;GO:0140297 DNA-binding transcription factor binding;GO:0140678 molecular function inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005794 Golgi apparatus;GO:0032991 protein-containing complex", "go_biological_process": "GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0009612 response to mechanical stimulus;GO:0045893 positive regulation of DNA-templated transcription;GO:0030514 negative regulation of BMP signaling pathway;GO:0016055 Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q99P67-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9EQL9-1", "uniprot_id": "SHRPN_RAT", "mass": 40287.0, "length": 381, "protein_name": "Sharpin", "gene_name": "Sharpin", "organism": "Rat", "refseq_name": "sharpin", "refseq_ac": "NP_112415", "gene_names_uniprotkb": "Sharpin", "gene_names_refseq": "Conneck1; Sharpin", "protein_names_uniprotkb": "Sharpin; Shank-associated RH domain-interacting protein", "protein_names_refseq": "SHANK-associated RH domain interacting protein; shank-associated RH domain-interacting protein; shank-interacting protein; sharpin", "tax_id": 10116, "disease": "atopic dermatitis (Disease Ontology:DOID:3310)", "pathway": " (rno:81859); (R-RNO-5357786); (R-RNO-5357905); (R-RNO-5357956)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "11178875;12753155;23897824", "class_list": "", "function": "Component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. The LUBAC complex is also involved in innate immunity by conjugating linear polyubiquitin chains at the surface of bacteria invading the cytosol to form the ubiquitin coat surrounding bacteria. LUBAC is not able to initiate formation of the bacterial ubiquitin coat, and can only promote formation of linear polyubiquitins on pre-existing ubiquitin. The bacterial ubiquitin coat acts as an 'eat-me' signal for xenophagy and promotes NF-kappa-B activation. Together with OTULIN, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis., [UniProtKB, UniProtKB]; The upregulation of Shank-interacting protein-like 1 (SIPL1) in the fundus of W/WV mice, and expression in the upper gastrointestinal tract suggest that the SIPL1 gene could be associated with interstitial cells of Cajal (ICC) function in mice and humans., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0030674 protein-macromolecule adaptor activity;GO:0031593 polyubiquitin modification-dependent protein binding;GO:0042802 identical protein binding;GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005829 cytosol;GO:0014069 postsynaptic density;GO:0030425 dendrite;GO:0071797 LUBAC complex", "go_biological_process": "GO:0097039 protein linear polyubiquitination;GO:2000348 regulation of CD40 signaling pathway;GO:0031424 keratinization;GO:0008544 epidermis development;GO:0050728 negative regulation of inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9EQL9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9ERU2-1", "uniprot_id": "ZNF22_RAT", "mass": 27286.0, "length": 237, "protein_name": "Zinc finger protein 22", "gene_name": "Znf22", "organism": "Rat", "refseq_name": "zinc finger protein 22", "refseq_ac": "NP_001012763", "gene_names_uniprotkb": "Znf22; Krox25; Zfp422", "gene_names_refseq": "Kox15; Krox-25; Zfp422; Znf22", "protein_names_uniprotkb": "Zinc finger protein 22; Zinc finger protein Krox-25", "protein_names_refseq": "krueppel-type zinc finger protein Krox-25; zinc finger protein 22 (KOX 15); zinc finger protein 22", "tax_id": 10116, "disease": "", "pathway": " (rno:360389)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "14706453;29393594", "class_list": "", "function": "Analysis revealed an intense expression of Krox-25 mRNA in rat and mouse teeth; results suggest that Krox-25 plays an important role as a transcription factor for the cytodifferentiation and amelogenesis of enamel epithelium., [RefSeq, PubMed]; Binds DNA through the consensus sequence 5'-CAATG-3'. May be involved in transcriptional regulation and may play a role in tooth formation (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5EAN1", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0042476 odontogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9ERU2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9ES58-1", "uniprot_id": "MO2R1_RAT", "mass": 35534.0, "length": 327, "protein_name": "Cell surface glycoprotein CD200 receptor 1", "gene_name": "Cd200r1", "organism": "Rat", "refseq_name": "cell surface glycoprotein CD200 receptor 1 precursor", "refseq_ac": "NP_076443", "gene_names_uniprotkb": "Cd200r1; Mox2r; Ox2r", "gene_names_refseq": "Cd200r1; Mox2r", "protein_names_uniprotkb": "Cell surface glycoprotein CD200 receptor 1; CD200 cell surface glycoprotein receptor; Cell surface glycoprotein OX2 receptor 1; OX102 antigen", "protein_names_refseq": "CD200 cell surface glycoprotein receptor; CD200 receptor; OX102 antigen; OX2 cell surface glycoprotein receptor; OX2 receptor; antigen identified by monoclonal antibody MRC OX-2 receptor; cell adhesion molecule; cell surface glycoprotein CD200 receptor 1 precursor; cell surface glycoprotein CD200 receptor 1; cell surface glycoprotein OX2 receptor 1", "tax_id": 10116, "disease": "", "pathway": " (rno:64357)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10981966;18164423;32664639;36565856;36591265;37971567;38237226", "class_list": "", "function": "Activation of the CD200/CD200R1 axis improves cognitive impairment by enhancing hippocampal neurogenesis via suppression of M1 microglial polarization and neuroinflammation in hypoxic-ischemic neonatal rats., [RefSeq, PubMed]; Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of pro-inflammatory molecules including TNF, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli (By similarity)., [UniProtKB]; Involvement of orexin-2 receptors in the CA1 region of the hippocampus in the extinction and reinstatement of methamphetamine-induced conditioned place preference in the rats., [RefSeq, PubMed]; Maternal Immune Activation Sensitizes Male Offspring Rats to Lipopolysaccharide-Induced Microglial Deficits Involving the Dysfunction of CD200-CD200R and CX3CL1-CX3CR1 Systems. Publication Status: Online-Only, [RefSeq, PubMed]; PPAR-gamma promotes the polarization of rat retinal microglia to M2 phenotype by regulating the expression of CD200-CD200R1 under hypoxia., [RefSeq, PubMed]; Specificity of CD200/CD200R pathway in LPS-induced lung inflammation. Publication Status: Online-Only, [RefSeq, PubMed]; The CD200-CD200R pathway seems of critical relevance for macrophage-mediated damage in autoimmune inflammation of the CNS., [RefSeq, PubMed]", "predicted_glycosites": 8, "predicted_n_glycosites": 8, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "Q6PS97", "ec_number_list": "", "go_molecular_function": "GO:0038023 signaling receptor activity;GO:0086080 protein binding involved in heterotypic cell-cell adhesion", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0043235 receptor complex;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:1905522 negative regulation of macrophage migration;GO:0032715 negative regulation of interleukin-6 production;GO:2000405 negative regulation of T cell migration;GO:0034113 heterotypic cell-cell adhesion;GO:0150077 regulation of neuroinflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q9ES58-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9ESM0-1", "uniprot_id": "IP6K1_RAT", "mass": 49366.0, "length": 433, "protein_name": "Inositol hexakisphosphate kinase 1", "gene_name": "Ip6k1", "organism": "Rat", "refseq_name": "inositol hexakisphosphate kinase 1", "refseq_ac": "NP_445768", "gene_names_uniprotkb": "Ip6k1; Ihpk1", "gene_names_refseq": "Ihpk1; Ip6k1; Itpk6", "protein_names_uniprotkb": "Inositol hexakisphosphate kinase 1; 2.7.4.21; Inositol hexaphosphate kinase 1; InsP6 kinase 1", "protein_names_refseq": "inositol hexakisphosphate kinase 1; inositol hexakisphosphate kinase 6; inositol hexaphosphate kinase 1; insP6 kinase 1", "tax_id": 10116, "disease": "", "pathway": " (rno:50560); (R-RNO-1855167); (R-RNO-1855191)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "22778403", "class_list": "", "function": "Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4., [UniProtKB, UniProtKB]; InsP6 suppresses excitatory neurotransmission via inhibition of the presynaptic synaptotagmin-1 C2B domain-mediated fusion via an interaction with the synaptotagmin Ca2+-binding sites., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.-.-;2.7.4.21;2.7.4.-", "go_molecular_function": "GO:0000828 inositol hexakisphosphate kinase activity;GO:0000832 inositol hexakisphosphate 5-kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0001650 fibrillar center", "go_biological_process": "GO:0046854 phosphatidylinositol phosphate biosynthetic process;GO:0120163 negative regulation of cold-induced thermogenesis;GO:0032958 inositol phosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9ESM0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9ET09-1", "uniprot_id": "MRS2_RAT", "mass": 49365.0, "length": 434, "protein_name": "Magnesium transporter MRS2 homolog, mitochondrial", "gene_name": "Mrs2", "organism": "Rat", "refseq_name": "magnesium transporter MRS2 homolog, mitochondrial precursor", "refseq_ac": "NP_076491", "gene_names_uniprotkb": "Mrs2; Mrs2l; Rpt", "gene_names_refseq": "Mrs2l; Mrs2; Rpt", "protein_names_uniprotkb": "Magnesium transporter MRS2 homolog, mitochondrial; MRS2-like protein", "protein_names_refseq": "MRS2 magnesium homeostasis factor homolog; MRS2 magnesium transporter; MRS2-like protein; MRS2-like, magnesium homeostasis factor; RPT protein similar to yeast MRS2; magnesium transporter MRS2 homolog, mitochondrial precursor; magnesium transporter MRS2 homolog, mitochondrial", "tax_id": 10116, "disease": "Barth syndrome (Disease Ontology:DOID:0050476); demyelinating disease (Disease Ontology:DOID:3213)", "pathway": " (rno:79032); (R-RNO-5223345)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "21253565;29393594;31100216", "class_list": "", "function": "Downregulation of aspartoacylase during the progression of myelin breakdown in the dmy mutant rat with mitochondrial magnesium channel MRS2 defect., [RefSeq, PubMed]; Magnesium transporter that mediates the influx of magnesium into the mitochondrial matrix and regulates magnesium metabolism (By similarity). Also permeable to calcium, sodium and potassium ions (By similarity). Required for normal expression of the mitochondrial respiratory complex I subunits (By similarity). May play a role in maintaining the inner mitochondrial membrane potential (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Transgenic rats showed that MRS2 was dominantly expressed in neurons rather than oligodendrocytes and was ultrastructurally observed in the inner membrane of mitochondria Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q4FZY6;Q5XIW5;Q9ET07;Q9ET08", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0015095 magnesium ion transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006089 lactate metabolic process;GO:0045016 mitochondrial magnesium ion transmembrane transport;GO:0006811 monoatomic ion transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9ET09-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9ET58-1", "uniprot_id": "KLF2_RAT", "mass": 37313.0, "length": 351, "protein_name": "Krueppel-like factor 2", "gene_name": "Klf2", "organism": "Rat", "refseq_name": "Krueppel-like factor 2", "refseq_ac": "NP_001007685", "gene_names_uniprotkb": "Klf2; Lklf", "gene_names_refseq": "Klf2; Lklf", "protein_names_uniprotkb": "Krueppel-like factor 2; Lung krueppel-like factor", "protein_names_refseq": "Krueppel-like factor 2; Kruppel-like factor 2 (lung); lung Kruppel-like factor; lung krueppel-like factor", "tax_id": 10116, "disease": "", "pathway": " (rno:306330)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "15033788;22673903;29079188;29393594;30628700;34147481;36343159;36638871", "class_list": "", "function": "Exposure to enriched environment ameliorated chronic unpredictable mild stress-induced depression-like symptoms in rats via regulating the miR-92a-3p/kruppel-like factor 2 (KLF2) pathway., [RefSeq, PubMed]; Hear stress may upregulate KLF2 expression, which may be associated with the integrinactin cytoskeleton system. Most importantly, the shear stressinduced differentiation of endothelial progenitor cells may be mediated by KLF2, [RefSeq, PubMed]; KLF2 reduces dexamethasone-induced injury to growth plate chondrocytes by inhibiting the Runx2-mediated PI3K/AKT and ERK signalling pathways., [RefSeq, PubMed]; KLF2 was remarkably downregulated in bleomycin-treated rats, both in mRNA and protein levels. Additionally, overexpression of KLF2 attenuated the destruction of the alveolar space and pulmonary interstitial collagen hyperplasia., [RefSeq, PubMed]; Klf2-Vav1-Rac1 axis promotes axon regeneration after peripheral nerve injury., [RefSeq, PubMed]; LKLF gene is not defective in diabetic prone BB rats and its expression is not compromised by mutation. (Klf2), [RefSeq, PubMed]; Transcription factor that binds to the CACCC box in the promoter of target genes such as HBB/beta globin or NOV and activates their transcription. Might be involved in transcriptional regulation by modulating the binding of the RARA nuclear receptor to RARE DNA elements (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0097533 cellular stress response to acid chemical;GO:1990859 cellular response to endothelin;GO:0043249 erythrocyte maturation;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0001701 in utero embryonic development", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q9ET58-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9JHB5-1", "uniprot_id": "TSNAX_RAT", "mass": 33005.0, "length": 290, "protein_name": "Translin-associated protein X", "gene_name": "Tsnax", "organism": "Rat", "refseq_name": "translin-associated protein X", "refseq_ac": "NP_071598", "gene_names_uniprotkb": "Tsnax; Trax", "gene_names_refseq": "Trax; Tsnax", "protein_names_uniprotkb": "Translin-associated protein X; Translin-associated factor X", "protein_names_refseq": "translin-associated protein X", "tax_id": 10116, "disease": "", "pathway": " (rno:64028); (R-RNO-426486)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "16617164;21124736;22673903;27624933;9681436", "class_list": "", "function": "A(2A)-R modulates the differentiation ability of trophic factors through a novel interacting protein, TRAX., [RefSeq, PubMed]; Acts in combination with TSN as an endonuclease involved in the activation of the RNA-induced silencing complex (RISC). Possible role in spermatogenesis (By similarity)., [UniProtKB]; PLCbeta through its ability to bind TRAX plays a key role in switching PC12 cells to their differentiated state., [RefSeq, PubMed]; Studies show that TRAX, localized in the cytosol and nucleus, competes with plasma-membrane bound Galpha(q) for PLCbeta1 binding thus stabilizing PLCbeta1 in other cellular compartments. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0046872 metal ion binding;GO:0044877 protein-containing complex binding;GO:0043565 sequence-specific DNA binding;GO:0004521 RNA endonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0030422 siRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9JHB5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9JHB9-1", "uniprot_id": "SG2A1_RAT", "mass": 10622.0, "length": 95, "protein_name": "Secretoglobin family 2A member 1", "gene_name": "Scgb2a1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Scgb2a1; Psbpc3", "gene_names_refseq": "", "protein_names_uniprotkb": "Secretoglobin family 2A member 1; Prostatic steroid-binding protein C3.2", "protein_names_refseq": "", "tax_id": 10116, "disease": "Perrault syndrome 6 (Disease Ontology:DOID:0080256)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "6685625", "class_list": "", "function": "Part of prostatein which is the major secretory glycoprotein of ventral prostate gland. Steroid-binding protein; can bind non-polar steroids, cholesterol and a group of small proline-rich peptides (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0044877 protein-containing complex binding;GO:0005496 steroid binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0030521 androgen receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9JHB9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9JHE5-1", "uniprot_id": "S38A2_RAT", "mass": 55554.0, "length": 504, "protein_name": "Sodium-coupled neutral amino acid symporter 2", "gene_name": "Slc38a2", "organism": "Rat", "refseq_name": "sodium-coupled neutral amino acid symporter 2", "refseq_ac": "NP_851604", "gene_names_uniprotkb": "Slc38a2; Ata2; Sa1; Sat2; Snat2", "gene_names_refseq": "Ata2; Atrc2; Sat2; Slc38a2; Snat2", "protein_names_uniprotkb": "Sodium-coupled neutral amino acid symporter 2; Amino acid transporter A2; Solute carrier family 38 member 2; System A amino acid transporter 2; System A transporter 1; System N amino acid transporter 2", "protein_names_refseq": "amino acid transporter A2; amino acid transporter cationic 2; amino acid transporter system A2; amino acid transporter, cationic 2 (low affinity); sodium-coupled neutral amino acid symporter 2; sodium-coupled neutral amino acid transporter 2; system A amino acid transporter 2; system A transporter 1; system N amino acid transporter 2", "tax_id": 10116, "disease": "", "pathway": " (rno:29642); (R-RNO-210500); (R-RNO-352230)", "pathway_count": 3, "publication_count": 23, "publication_id_list": "10747860;10811809;10859363;11311116;11716780;11756489;11834730;12021389;12054432;15561425;16616430;16629640;17488712;18319257;18330498;18832333;19589777;21158741;22673903;27049295;27355203;29475006;29678469", "class_list": "", "function": "Results show that SNAT2 contains 11 transmembrane domains (TMDs) with an intracellular N terminus and an extracellular C terminus, [RefSeq, PubMed]; Symporter that cotransports neutral amino acids and sodium ions from the extracellular to the intracellular side of the cell membrane (PubMed:10747860, PubMed:10811809, PubMed:10859363, PubMed:11716780, PubMed:11756489, PubMed:12054432, PubMed:16629640, PubMed:18319257, PubMed:18330498, PubMed:18832333, PubMed:19589777, PubMed:21158741, PubMed:27355203). The transport is pH-sensitive, Li(+)-intolerant, electrogenic, driven by the Na(+) electrochemical gradient and cotransports of neutral amino acids and sodium ions with a stoichiometry of 1:1 (PubMed:10747860, PubMed:10811809, PubMed:10859363, PubMed:11716780, PubMed:11756489, PubMed:12054432, PubMed:16629640, PubMed:18319257, PubMed:19589777, PubMed:21158741). May function in the transport of amino acids at the blood-brain barrier (PubMed:12021389). May function in the transport of amino acids in the supply of maternal nutrients to the fetus through the placenta (By similarity). Maintains a key metabolic glutamine/glutamate balance underpinning retrograde signaling by dendritic release of the neurotransmitter glutamate (PubMed:18832333). Transports L-proline in differentiating osteoblasts for the efficient synthesis of proline-enriched proteins and provides proline essential for osteoblast differentiation and bone formation during bone development (By similarity)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, UniProtKB]; There is a disulfide bond between Cys245 and Cys279 in SNAT2 which has no effect on cell surface trafficking, as well as transporter function Publication Status: Online-Only, [RefSeq, PubMed]; These results suggested that Astragalus polysacchrides could improve muscle wasting through Akt/mTOR, ubiquitin proteasome and autophagy signalling, and SLC38A2 may be one of potential targets., [RefSeq, PubMed]; Treatment with glutamine and its combination with liraglutide significantly increased pancreatic expression of SNAT2 by approximately 30-35 folds., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 3, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 3, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 3, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 18, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q9JI88", "ec_number_list": "", "go_molecular_function": "GO:0005298 proline:sodium symporter activity;GO:0015171 amino acid transmembrane transporter activity;GO:0015175 neutral L-amino acid transmembrane transporter activity;GO:0015186 L-glutamine transmembrane transporter activity;GO:0015194 L-serine transmembrane transporter activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005903 brush border;GO:0030424 axon;GO:0030425 dendrite", "go_biological_process": "GO:0033120 positive regulation of RNA splicing;GO:0015824 proline transport;GO:0015825 L-serine transport;GO:0031460 glycine betaine transport;GO:0032328 alanine transport", "synthesized_glycan_count": 0, "hit_score": 2.7, "record_id": "Q9JHE5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9JHY2-1", "uniprot_id": "SFXN3_RAT", "mass": 35465.0, "length": 321, "protein_name": "Sideroflexin-3", "gene_name": "Sfxn3", "organism": "Rat", "refseq_name": "sideroflexin-3", "refseq_ac": "NP_075237", "gene_names_uniprotkb": "Sfxn3", "gene_names_refseq": "SLC64A3; Sfxn3; TCC", "protein_names_uniprotkb": "Sideroflexin-3", "protein_names_refseq": "sideroflexin-3; solute carrier family 64 member 3; tricarboxylate carrier-like protein", "tax_id": 10116, "disease": "", "pathway": " (rno:65042)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "12008022;15864810;28100784;29393594;31177362;38843836", "class_list": "", "function": "Citrate transporter protein-like protein/Sfxn3 and some other family members might be important in the differentiation of pancreatic beta-cells, [RefSeq, PubMed]; Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway. Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Sideroflexin 3 is a Mitochondrial Protein Enriched in Neurons., [RefSeq, PubMed]; TCC protein as well as mRNA was widely expressed in brain, and the protein expression was strong in neuronal cells in the hippocampus, the olfactory bulb, the corpus mamillare and the cerebellum., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "G3V804", "ec_number_list": "", "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0015194 L-serine transmembrane transporter activity;GO:0015075 monoatomic ion transmembrane transporter activity;GO:0005371 tricarboxylate secondary active transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0006730 one-carbon metabolic process;GO:1990542 mitochondrial transmembrane transport;GO:0140300 serine import into mitochondrion;GO:0006865 amino acid transport", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q9JHY2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9JI61-1", "uniprot_id": "LRAT_RAT", "mass": 25810.0, "length": 231, "protein_name": "Lecithin retinol acyltransferase", "gene_name": "Lrat", "organism": "Rat", "refseq_name": "lecithin retinol acyltransferase", "refseq_ac": "NP_071616", "gene_names_uniprotkb": "Lrat", "gene_names_refseq": "Lrat", "protein_names_uniprotkb": "Lecithin retinol acyltransferase; 2.3.1.135; Phosphatidylcholine--retinol O-acyltransferase", "protein_names_refseq": "lecithin retinol acyltransferase; lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase); phosphatidylcholine--retinol O-acyltransferase", "tax_id": 10116, "disease": "Leber congenital amaurosis 14 (Disease Ontology:DOID:0110188); retinitis pigmentosa (Disease Ontology:DOID:10584)", "pathway": " (rno:64047); (R-RNO-2453902); (R-RNO-975634)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "11108736;17158102;18544127;1885578;3410848;34281288", "class_list": "", "function": "The Lrat(-/-) Rat: CRISPR/Cas9 Construction and Phenotyping of a New Animal Model for Retinitis Pigmentosa. Publication Status: Online-Only, [RefSeq, PubMed]; Transfers the acyl group from the sn-1 position of phosphatidylcholine to all-trans retinol, producing all-trans retinyl esters (PubMed:3410848). Retinyl esters are storage forms of vitamin A (By similarity). LRAT plays a critical role in vision (By similarity). It provides the all-trans retinyl ester substrates for the isomerohydrolase which processes the esters into 11-cis-retinol in the retinal pigment epithelium; due to a membrane-associated alcohol dehydrogenase, 11 cis-retinol is oxidized and converted into 11-cis-retinaldehyde which is the chromophore for rhodopsin and the cone photopigments (By similarity). Required for the survival of cone photoreceptors and correct rod photoreceptor cell morphology (By similarity)., [UniProtKB, PubMed, UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.1.135", "go_molecular_function": "GO:0016416 O-palmitoyltransferase activity;GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity;GO:0019841 retinol binding;GO:0001972 retinoic acid binding;GO:0008374 O-acyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005791 rough endoplasmic reticulum;GO:0048471 perinuclear region of cytoplasm;GO:0005789 endoplasmic reticulum membrane;GO:0005771 multivesicular body", "go_biological_process": "GO:0032370 positive regulation of lipid transport;GO:0001523 retinoid metabolic process;GO:0009617 response to bacterium;GO:0042572 retinol metabolic process;GO:1990830 cellular response to leukemia inhibitory factor", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9JI61-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9JIP0-1", "uniprot_id": "TRPV5_RAT", "mass": 82454.0, "length": 723, "protein_name": "Transient receptor potential cation channel subfamily V member 5", "gene_name": "Trpv5", "organism": "Rat", "refseq_name": "transient receptor potential cation channel subfamily V member 5 isoform X1", "refseq_ac": "XP_063141473", "gene_names_uniprotkb": "Trpv5; Cat2; Ecac1; Ecac", "gene_names_refseq": "CaT2; Ecac1; Trpv5", "protein_names_uniprotkb": "Transient receptor potential cation channel subfamily V member 5; CaT2; Calcium transporter 2; ECaC1; Epithelial calcium channel 1; OTRPC3; Osm-9-like TRP channel 3; TrpV5", "protein_names_refseq": "transient receptor potential cation channel subfamily V member 5 isoform X1", "tax_id": 10116, "disease": "pre-eclampsia (Disease Ontology:DOID:10591); gestational diabetes (Disease Ontology:DOID:11714)", "pathway": " (rno:116469); (R-RNO-3295583)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "10875938", "class_list": "", "function": "Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine (PubMed:10875938). Required for normal Ca(2+) reabsorption in the kidney distal convoluted tubules (By similarity). The channel is activated by low internal calcium level and the current exhibits an inward rectification (By similarity). A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay (By similarity). Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating (By similarity)., [UniProtKB, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q5UC98;Q9JJL2", "ec_number_list": "2.7.11.1", "go_molecular_function": "GO:0005262 calcium channel activity;GO:0005516 calmodulin binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016324 apical plasma membrane;GO:0034704 calcium channel complex", "go_biological_process": "GO:0051289 protein homotetramerization;GO:0006816 calcium ion transport;GO:0035809 regulation of urine volume;GO:0070588 calcium ion transmembrane transport;GO:0060402 calcium ion transport into cytosol", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9JIP0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9JJP0-1", "uniprot_id": "S20A1_RAT", "mass": 74187.0, "length": 681, "protein_name": "Sodium-dependent phosphate transporter 1", "gene_name": "Slc20a1", "organism": "Rat", "refseq_name": "sodium-dependent phosphate transporter 1", "refseq_ac": "NP_112410", "gene_names_uniprotkb": "Slc20a1; Pit1", "gene_names_refseq": "PiT-1; Slc20a1", "protein_names_uniprotkb": "Sodium-dependent phosphate transporter 1; Phosphate transporter 1; PiT-1; RPHO-1; Solute carrier family 20 member 1", "protein_names_refseq": "RPHO-1; phosphate transporter 1; sodium-dependent phosphate transporter 1; solute carrier family 20 (phosphate transporter), member 1", "tax_id": 10116, "disease": "", "pathway": " (rno:81826); (R-RNO-427652)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "14985238;15564340;22673903;26581047;26782594;28123180;9528951", "class_list": "", "function": "Apelin ameliorates VC by suppressing osteoblastic differentiation of VSMCs through downregulation of Pit-1., [RefSeq, PubMed]; Mechanism involving TRPM7 and Pit-1 underpins the magnesium-mediated reversal of high-phosphate-associated vascular calcification, [RefSeq, PubMed]; NaPi-III mRNA expression is affected by hyperphosphatemia. Publication Status: Online-Only, [RefSeq, PubMed]; PiT-1 and PiT-2 were detected at the basolateral membrane of hepatocytes., [RefSeq, PubMed]; Sodium-phosphate cotransporter (PiT-1) soleus and red gastrocnemius was similar and seven- to eightfold greater than PiT-1 expression in white gastrocnemius. PiT-1 expression did not match pattern of P(i) uptake across fiber types., [RefSeq, PubMed]; Sodium-phosphate symporter which preferentially transports the monovalent form of phosphate with a stoichiometry of two sodium ions per phosphate ion (PubMed:9528951). May play a role in extracellular matrix and cartilage calcification as well as in vascular calcification (By similarity). Essential for cell proliferation but this function is independent of its phosphate transporter activity (By similarity)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005316 high-affinity phosphate:sodium symporter activity;GO:0005315 phosphate transmembrane transporter activity;GO:0005436 sodium:phosphate symporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0008283 cell population proliferation;GO:0031214 biomineral tissue development;GO:0006814 sodium ion transport;GO:0006817 phosphate ion transport;GO:0035435 phosphate ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q9JJP0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9JM00-1", "uniprot_id": "VAX1_RAT", "mass": 35012.0, "length": 336, "protein_name": "Ventral anterior homeobox 1", "gene_name": "Vax1", "organism": "Rat", "refseq_name": "ventral anterior homeobox 1", "refseq_ac": "NP_072158", "gene_names_uniprotkb": "Vax1", "gene_names_refseq": "Vax1", "protein_names_uniprotkb": "Ventral anterior homeobox 1", "protein_names_refseq": "ventral anterior homeobox 1; ventral anterior homeobox containing gene 1", "tax_id": 10116, "disease": "syndromic microphthalmia 11 (Disease Ontology:DOID:0111804)", "pathway": " (rno:64571)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcription factor that may function in dorsoventral specification of the forebrain. Required for axon guidance and major tract formation in the developing forebrain. May contribute to the differentiation of the neuroretina, pigmented epithelium and optic stalk (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0031490 chromatin DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007399 nervous system development;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q9JM00-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9QUZ8-1", "uniprot_id": "GMEB1_RAT", "mass": 61194.0, "length": 562, "protein_name": "Glucocorticoid modulatory element-binding protein 1", "gene_name": "Gmeb1", "organism": "Rat", "refseq_name": "glucocorticoid modulatory element-binding protein 1", "refseq_ac": "NP_001102738", "gene_names_uniprotkb": "Gmeb1", "gene_names_refseq": "Gmeb1; RGD1563208", "protein_names_uniprotkb": "Glucocorticoid modulatory element-binding protein 1; GMEB-1", "protein_names_refseq": "GMEB-1; glucocorticoid modulatory element-binding protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:500558)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "7665613", "class_list": "", "function": "Acts as a DNA-binding transcriptional regulator involved in modulating the expression of genes responsive to glucocorticoid signaling. Specifically binds AT-rich DNA motifs known as glucocorticoid modulatory elements (GMEs), repressing or enhancing transcription depending on cellular context. Forms heterodimeric complexes with GMEB2, which enhances its DNA-binding specificity and transcriptional activity. This complex plays a critical role in the repression of glucocorticoid receptor (GR/NR3C1) transcriptional activity, acting as a negative modulator of glucocorticoid signaling (By similarity). Regulates dopamine-enriched midbrain genes, including tyrosine hydroxylase/TH and the dopamine transporter SLC6A3, essential for dopamine signaling (By similarity). Also binds the transferrin receptor promoter. In the cytoplasm, inhibits caspase activation and neuronal apoptosis by stabilizing CFLARL and blocking pro-caspase 8 activation (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B0BN09", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0030674 protein-macromolecule adaptor activity;GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0043066 negative regulation of apoptotic process;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9QUZ8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9QYE2-1", "uniprot_id": "SO1A6_RAT", "mass": 74451.0, "length": 670, "protein_name": "Solute carrier organic anion transporter family member 1A6", "gene_name": "Slco1a6", "organism": "Rat", "refseq_name": "solute carrier organic anion transporter family member 1A6", "refseq_ac": "NP_570092", "gene_names_uniprotkb": "Slco1a6; Oatp5; Slc21a13", "gene_names_refseq": "Oatp5; Slc21a13; Slco1a6", "protein_names_uniprotkb": "Solute carrier organic anion transporter family member 1A6; Kidney-specific organic anion-transporting polypeptide 5; OATP-5; Solute carrier family 21 member 13", "protein_names_refseq": "OATP-5; kidney-specific organic anion transporting polypeptide 5; solute carrier family (organic anion transporter) member 13; solute carrier family 21 member 13; solute carrier organic anion transporter family member 1A6", "tax_id": 10116, "disease": "", "pathway": " (rno:84608)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May mediate the Na(+)-independent transport of organic anions., [UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015125 bile acid transmembrane transporter activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0006811 monoatomic ion transport;GO:0015721 bile acid and bile salt transport;GO:0043252 sodium-independent organic anion transport;GO:0097421 liver regeneration;GO:0055085 transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q9QYE2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9R0K8-1", "uniprot_id": "STC2_RAT", "mass": 32622.0, "length": 296, "protein_name": "Stanniocalcin-2", "gene_name": "Stc2", "organism": "Rat", "refseq_name": "stanniocalcin-2 precursor", "refseq_ac": "NP_071566", "gene_names_uniprotkb": "Stc2", "gene_names_refseq": "Stc2", "protein_names_uniprotkb": "Stanniocalcin-2; STC-2", "protein_names_refseq": "STC-2; stanniocalcin-2 precursor", "tax_id": 10116, "disease": "hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (rno:63878); (R-RNO-381426); (R-RNO-8957275)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "10508929;15485913", "class_list": "", "function": "Has an anti-hypocalcemic action on calcium and phosphate homeostasis., [UniProtKB]; Induced STC2 expression is an essential feature of survival component of the unfolded-protein response, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019899 enzyme binding;GO:0042803 protein homodimerization activity;GO:0005179 hormone activity;GO:0020037 heme binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0006979 response to oxidative stress;GO:0010629 negative regulation of gene expression;GO:0006874 intracellular calcium ion homeostasis;GO:0071456 cellular response to hypoxia;GO:0040015 negative regulation of multicellular organism growth", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9R0K8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9R168-1", "uniprot_id": "SFRP1_RAT", "mass": 18072.0, "length": 158, "protein_name": "Secreted frizzled-related protein 1", "gene_name": "Sfrp1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Sfrp1", "gene_names_refseq": "", "protein_names_uniprotkb": "Secreted frizzled-related protein 1; sFRP-1", "protein_names_refseq": "", "tax_id": 10116, "disease": "leiomyoma (Disease Ontology:DOID:127); renal cell carcinoma (Disease Ontology:DOID:4450); in situ carcinoma (Disease Ontology:DOID:8719)", "pathway": " (rno:84402)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "11287180", "class_list": "", "function": "Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase. In kidney development, inhibits tubule formation and bud growth in metanephroi. Inhibits WNT1/WNT4-mediated TCF-dependent transcription., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005109 frizzled binding;GO:0008201 heparin binding;GO:0042802 identical protein binding;GO:0017147 Wnt-protein binding;GO:0004197 cysteine-type endopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005829 cytosol;GO:0009986 cell surface;GO:0031012 extracellular matrix", "go_biological_process": "GO:0045880 positive regulation of smoothened signaling pathway;GO:0060527 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis;GO:0046851 negative regulation of bone remodeling;GO:0008284 positive regulation of cell population proliferation;GO:0008285 negative regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9R168-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9R2C1-1", "uniprot_id": "SERP1_RAT", "mass": 7374.0, "length": 66, "protein_name": "Stress-associated endoplasmic reticulum protein 1", "gene_name": "Serp1", "organism": "Rat", "refseq_name": "stress-associated endoplasmic reticulum protein 1", "refseq_ac": "NP_110462", "gene_names_uniprotkb": "Serp1; Ramp4", "gene_names_refseq": "RAMP4; Serp1", "protein_names_uniprotkb": "Stress-associated endoplasmic reticulum protein 1; Ribosome-attached membrane protein 4", "protein_names_refseq": "ribosome associated membrane protein 4; ribosome-attached membrane protein 4; stress-associated endoplasmic reticulum protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:80881); (R-RNO-9609523)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10469658;10601334;35419615", "class_list": "", "function": "Interacts with target proteins during their translocation into the lumen of the endoplasmic reticulum. Protects unfolded target proteins against degradation during ER stress. May facilitate glycosylation of target proteins after termination of ER stress. May modulate the use of N-glycosylation sites on target proteins., [UniProtKB, PubMed, PubMed, UniProtKB, UniProtKB]; Interacts with target proteins during translocation into the lumen of the endoplasmic reticulum. Protects unfolded target proteins against degradation and facilitate correct glycosylation., [UniProtKB, UniProtKB]; SERP1 reduces inchoate acute hepatic injury through regulation of endoplasmic reticulum stress via the GSK3beta/betacatenin/TCF/LEF signaling pathway., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q794E7", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0005881 cytoplasmic microtubule", "go_biological_process": "GO:0032024 positive regulation of insulin secretion;GO:0001501 skeletal system development;GO:0006006 glucose metabolic process;GO:0009791 post-embryonic development;GO:0045727 positive regulation of translation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9R2C1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9WTZ3-1", "uniprot_id": "MBTP1_RAT", "mass": 117462.0, "length": 1052, "protein_name": "Membrane-bound transcription factor site-1 protease", "gene_name": "Mbtps1", "organism": "Rat", "refseq_name": "membrane-bound transcription factor site-1 protease precursor", "refseq_ac": "NP_446021", "gene_names_uniprotkb": "Mbtps1; S1p; Ski1", "gene_names_refseq": "Mbtps1; S1p; Ski-1", "protein_names_uniprotkb": "Membrane-bound transcription factor site-1 protease; 3.4.21.112; Endopeptidase S1P; SKI-1; Subtilisin/kexin isozyme 1", "protein_names_refseq": "S1P endopeptidase; endopeptidase S1P; membrane-bound transcription factor protease, site 1; membrane-bound transcription factor site-1 protease precursor; membrane-bound transcription factor site-1 protease; subtilisin/kexin isozyme 1", "tax_id": 10116, "disease": "idiopathic scoliosis (Disease Ontology:DOID:0060250); spondyloepiphyseal dysplasia Kondo-Fu type (Disease Ontology:DOID:0112283)", "pathway": " (rno:89842); (R-RNO-1655829); (R-RNO-381033); (R-RNO-381426); (R-RNO-8874177); (R-RNO-8874211); (R-RNO-8957275)", "pathway_count": 7, "publication_count": 4, "publication_id_list": "17643267;33738762;37358010;9990022", "class_list": "", "function": "Molecular Mechanism of the ATF6alpha/S1P/S2P Signaling Pathway in Hippocampal Neuronal Apoptosis in SPS Rats., [RefSeq, PubMed]; S1P affects and sustains all key cellular processes responsible for wound repair and point to a unique potential for this molecule in the therapy of diabetic wounds, particularly as an angiogenic agent in treatment of diabetic wounds., [RefSeq, PubMed]; Serine protease that cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4: known substrates include SREBF1/SREBP1, SREBF2/SREBP2, BDNF, GNPTAB, ATF6, ATF6B and FAM20C. Cleaves substrates after Arg-Ser-Val-Leu (SREBP2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu. Catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2. Also mediates the first step in the proteolytic activation of the cyclic AMP-dependent transcription factor ATF-6 (ATF6 and ATF6B). Mediates the protein cleavage of GNPTAB into subunit alpha and beta, thereby participating in biogenesis of lysosomes. Cleaves the propeptide from FAM20C which is required for FAM20C secretion from the Golgi apparatus membrane and for enhancement of FAM20C kinase activity, promoting osteoblast differentiation and biomineralization. Involved in the regulation of M6P-dependent Golgi-to-lysosome trafficking of lysosomal enzymes. It is required for the activation of CREB3L2/BBF2H7, a transcriptional activator of MIA3/TANGO and other genes controlling mega vesicle formation. Therefore, it plays a key role in the regulation of mega vesicle-mediated collagen trafficking. Promotes FAD binding to the ETFA/ETFB complex and is therefore involved in mitochondrial respiratory chain regulation. In astrocytes and osteoblasts, upon DNA damage and ER stress, mediates the first step of the regulated intramembrane proteolytic activation of the transcription factor CREB3L1, leading to the inhibition of cell-cycle progression., [UniProtKB, UniProtKB]; Spns2/S1P: it takes two to tango with inflammation and metabolic rewiring during sepsis., [RefSeq, PubMed]", "predicted_glycosites": 8, "predicted_n_glycosites": 6, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "G3V7Z2", "ec_number_list": "5.3.4.1;3.1.1.4;3.1.1.3;1.11.1.27;1.16.3.1;1.11.1.9;1.16.3.4;3.4.21.69;3.4.21.-;3.4.24.81;2.4.1.145;3.6.4.-;3.2.1.51;1.8.3.2;3.4.21.112", "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005576 extracellular region;GO:0005739 mitochondrion;GO:0005794 Golgi apparatus;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0006629 lipid metabolic process;GO:0008203 cholesterol metabolic process;GO:0016485 protein processing;GO:0007040 lysosome organization", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9WTZ3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9WUK0-1", "uniprot_id": "INSL3_RAT", "mass": 14110.0, "length": 128, "protein_name": "Insulin-like 3", "gene_name": "Insl3", "organism": "Rat", "refseq_name": "insulin-like 3 precursor", "refseq_ac": "NP_446132", "gene_names_uniprotkb": "Insl3; Rlf", "gene_names_refseq": "Insl3; Rlf", "protein_names_uniprotkb": "Insulin-like 3; Ley-I-L; Leydig insulin-like peptide; Relaxin-like factor", "protein_names_refseq": "Leydig insulin-like peptide relaxin-like factor; insulin-like 3 precursor; ley-I-L; relaxin-like factor", "tax_id": 10116, "disease": "", "pathway": " (rno:114215); (R-RNO-444821)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "10542371;12114498;20631401;21633115;24169563", "class_list": "", "function": "Data suggest that INSL3 signaling in fetal gubernaculum induces morphogenetic programs in male genitalia; investigation of differences in gene expression regulation by INSL3 in gubernaculum of male and female genitalia, [RefSeq, PubMed]; Demonstration of INSL3 as the ligand for LGR8 facilitates understanding of the mechanism of testis descent and allows studies on the role of INSL3 in gonadal and other physiological processes, [RefSeq, PubMed]; INSL3 is a key theca cell-derived growth factor for preantral follicle and its action is mediated by GDF9, [RefSeq, PubMed]; Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor (By similarity)., [UniProtKB]; The observed postnatal difference in gubernacular malformations between two rate strains is due to different levels of the insl3 receptor differ among strains., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9WUK1", "ec_number_list": "", "go_molecular_function": "GO:0002020 protease binding;GO:0005179 hormone activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0001701 in utero embryonic development;GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0008284 positive regulation of cell population proliferation;GO:0008285 negative regulation of cell population proliferation;GO:0043066 negative regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9WUK0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9WUK5-1", "uniprot_id": "INHBC_RAT", "mass": 39335.0, "length": 351, "protein_name": "Inhibin beta C chain", "gene_name": "Inhbc", "organism": "Rat", "refseq_name": "inhibin beta C chain precursor", "refseq_ac": "NP_072136", "gene_names_uniprotkb": "Inhbc", "gene_names_refseq": "Inhbc", "protein_names_uniprotkb": "Inhibin beta C chain; Activin beta-C chain", "protein_names_refseq": "activin beta-C chain; activin/inhibin beta C; inhibin beta C chain precursor; inhibin beta C chain; inhibin beta C subunit", "tax_id": 10116, "disease": "", "pathway": " (rno:64549); (R-RNO-209822)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "11932210;12865331;15821113;16085335;32141565", "class_list": "", "function": "Data suggest that betaA- and betaC-activin subunit proteins and follistatin are autocrine growth regulators in regenerating liver and when expressed independently lead to hepatocyte apoptosis or mitosis in a subset of hepatocytes., [RefSeq, PubMed]; Expression and dimerization of the rat activin subunits betaC and betaE: evidence for the ormation of novel activin dimers., [RefSeq, PubMed]; First report of a biological activity of activin C and E supports an involvement in liver tissue homeostasis, [RefSeq, PubMed]; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins., [UniProtKB]; The potential mechanism of INHBC and CSF1R in diabetic nephropathy., [RefSeq, PubMed]; These results indicate that liver regeneration is accelerated in activin betaC-overexpressing liver, and that betaC may function to promote replication of hepatocytes during liver regeneration., [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q5FVS9", "ec_number_list": "", "go_molecular_function": "GO:0005125 cytokine activity;GO:0005179 hormone activity;GO:0008083 growth factor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0071397 cellular response to cholesterol;GO:0007178 cell surface receptor protein serine/threonine kinase signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9WUK5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9WUS0-1", "uniprot_id": "KAD4_RAT", "mass": 25203.0, "length": 223, "protein_name": "Adenylate kinase 4, mitochondrial", "gene_name": "Ak4", "organism": "Rat", "refseq_name": "adenylate kinase 4, mitochondrial isoform 1", "refseq_ac": "NP_058831", "gene_names_uniprotkb": "Ak4; AK3L1; AK4", "gene_names_refseq": "AK 4; Ak3l1; Ak3l2; Ak4", "protein_names_uniprotkb": "Adenylate kinase 4, mitochondrial; 2.7.4.4; 2.7.4.6; Adenylate kinase 3-like; GTP:AMP phosphotransferase AK4", "protein_names_refseq": "ATP-AMP transphosphorylase; GTP:AMP phosphotransferase AK4, mitochondrial; adenylate kinase 3 alpha-like 1; adenylate kinase 3-like 1; adenylate kinase 3-like 2; adenylate kinase 4, mitochondrial isoform 1; adenylate kinase 4, mitochondrial; adenylate kinase isoenzyme 4, mitochondrial", "tax_id": 10116, "disease": "acute kidney tubular necrosis (Disease Ontology:DOID:12556)", "pathway": " (rno:29223); (R-RNO-499943)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "37932484;9813319", "class_list": "", "function": "Broad-specificity mitochondrial nucleoside phosphate kinase involved in cellular nucleotide homeostasis by catalyzing nucleoside-phosphate interconversions. Similar to other adenylate kinases, preferentially catalyzes the phosphorylation of the nucleoside monophosphate AMP with ATP as phosphate donor to produce ADP. Phosphorylates only AMP when using GTP as phosphate donor. In vitro, can also catalyze the phosphorylation of CMP, dAMP and dCMP and use GTP as an alternate phosphate donor. Moreover, exhibits a diphosphate kinase activity, producing ATP, CTP, GTP, UTP, TTP, dATP, dCTP and dGTP from the corresponding diphosphate substrates with either ATP or GTP as phosphate donors. Plays a role in controlling cellular ATP levels by regulating phosphorylation and activation of the energy sensor protein kinase AMPK. Plays a protective role in the cellular response to oxidative stress., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity., [UniProtKB, HAMAP]; MicroRNA-124 conducts neuroprotective effect via inhibiting AK4/ATF3 after subarachnoid hemorrhage., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.4.6;2.7.4.14;2.7.4.4;2.7.4.3;2.7.13.3;2.7.4.10;3.1.11.-;2.7.11.1;2.7.4.18;3.1.24.-;1.3.1.124", "go_molecular_function": "GO:0004017 AMP kinase activity;GO:0046899 nucleoside triphosphate adenylate kinase activity;GO:0005524 ATP binding;GO:0005525 GTP binding;GO:0004550 nucleoside diphosphate kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006172 ADP biosynthetic process;GO:0046033 AMP metabolic process;GO:0001889 liver development;GO:0071456 cellular response to hypoxia;GO:0009410 response to xenobiotic stimulus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9WUS0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9WV75-1", "uniprot_id": "SPON2_RAT", "mass": 36015.0, "length": 330, "protein_name": "Spondin-2", "gene_name": "Spon2", "organism": "Rat", "refseq_name": "spondin-2 precursor", "refseq_ac": "NP_612542", "gene_names_uniprotkb": "Spon2", "gene_names_refseq": "Spon2", "protein_names_uniprotkb": "Spondin-2; Mindin", "protein_names_refseq": "F-spondin; mindin; spondin 2, extracellular matrix protein; spondin-2 precursor; spondin-2-like", "tax_id": 10116, "disease": "meningioma (Disease Ontology:DOID:3565)", "pathway": " (rno:171569); (R-RNO-5173214)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "10409509;16300627;16736493;18780763;19903741;22592270;25751394", "class_list": "", "function": "3'G-oligodeoxyribonucleotides enhance nucleus YB-1 to inhibit F-spondin leading to cell death and neurite retraction of embryonic neuron cells., [RefSeq, PubMed]; Cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens (By similarity)., [UniProtKB, PubMed]; F-spondin can alter cell differentiation in multiple ways, depending upon its concentration and distribution between substrate-attached and soluble forms., [RefSeq, PubMed]; Mindin protects against vascular hyperplasia by suppression of abnormal VSMC proliferation, migration and phenotypic switching in an AKT-dependent manner., [RefSeq, PubMed]; NMR solution structures of TSR domains of F-spondin showed that they have an unusual fold that is characterized by a long, nonglobular shape, consisting of two beta-strands and one irregular extended strand., [RefSeq, PubMed]; Spon2 protein was 9.2-fold & mRNA 16.5-fold higher in the T3-treated thyroidectomized (Tx)rats compared with the Tx group. Publication Status: Online-Only, [RefSeq, PubMed]; These studies identify F-spondin as a novel protein in osteoarthritis cartilage, where it may act in situ at lesional areas to activate latent TGF-beta and induce cartilage degradation. Erratum:[FASEB J. 2009 Aug;23(8):2790], [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 1, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0046872 metal ion binding;GO:0001530 lipopolysaccharide binding;GO:0003823 antigen binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix", "go_biological_process": "GO:0007155 cell adhesion;GO:0032496 response to lipopolysaccharide;GO:0045087 innate immune response;GO:0051607 defense response to virus;GO:0032755 positive regulation of interleukin-6 production", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q9WV75-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9WVB7-1", "uniprot_id": "LENEP_RAT", "mass": 6925.0, "length": 61, "protein_name": "Lens epithelial cell protein LEP503", "gene_name": "Lenep", "organism": "Rat", "refseq_name": "lens epithelial cell protein LEP503", "refseq_ac": "NP_446066", "gene_names_uniprotkb": "Lenep; Lep503", "gene_names_refseq": "Elp; Lenep; Lep503", "protein_names_uniprotkb": "Lens epithelial cell protein LEP503", "protein_names_refseq": "Lens epithelium 503; lens epithelial cell protein LEP503; lens epithelial protein 503", "tax_id": 10116, "disease": "", "pathway": " (rno:113917)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10655141;7641850", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q62699", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9WVB7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9Z0M4-1", "uniprot_id": "MCP_RAT", "mass": 39787.0, "length": 355, "protein_name": "Membrane cofactor protein", "gene_name": "Cd46", "organism": "Rat", "refseq_name": "membrane cofactor protein precursor", "refseq_ac": "NP_062063", "gene_names_uniprotkb": "Cd46; Mcp", "gene_names_refseq": "Cd46; Mcp", "protein_names_uniprotkb": "Membrane cofactor protein", "protein_names_refseq": "CD46 antigen, complement regulatory protein; CD46 molecule, complement regulatory protein; membrane cofactor protein precursor; membrane cofactor protein", "tax_id": 10116, "disease": "", "pathway": " (rno:29333); (R-RNO-977606)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10469244;15215199;9799332", "class_list": "", "function": "May be involved in the fusion of the spermatozoa with the oocyte during fertilization., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 1, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0045296 cadherin binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0016020 membrane;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0010628 positive regulation of gene expression;GO:0010629 negative regulation of gene expression;GO:0007338 single fertilization;GO:0071636 positive regulation of transforming growth factor beta production", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9Z0M4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9Z0X2-1", "uniprot_id": "SL9A5_RAT", "mass": 99108.0, "length": 898, "protein_name": "Sodium/hydrogen exchanger 5", "gene_name": "Slc9a5", "organism": "Rat", "refseq_name": "sodium/hydrogen exchanger 5 precursor", "refseq_ac": "NP_620213", "gene_names_uniprotkb": "Slc9a5; Nhe5", "gene_names_refseq": "Nhe5; Slc9a5", "protein_names_uniprotkb": "Sodium/hydrogen exchanger 5; NHE-5; Na(+)/H(+) exchanger 5; Solute carrier family 9 member 5", "protein_names_refseq": "NHE-5; Na(+)/H(+) exchanger 5; sodium/hydrogen exchanger 5 precursor; sodium/hydrogen exchanger 5; solute carrier family 9 (sodium/hydrogen exchanger), member 5; solute carrier family 9 member 5; solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5", "tax_id": 10116, "disease": "nephrolithiasis (Disease Ontology:DOID:585); end stage renal disease (Disease Ontology:DOID:783)", "pathway": " (rno:192215); (R-RNO-425986)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "12576672;19248819;24006492;26700318;9933642", "class_list": "", "function": "Data indicate that NHE5 depletion reduces cell surface abundance of TrkA and nerve growth factor (NGF)-induced PI3K signaling., [RefSeq, PubMed]; NHE5 facilitates MET recycling to the plasma membrane, protects MET from degradation, and modulates HGF-induced phosphatidylinositol-3-kinase and mitogen-activated protein kinase signaling., [RefSeq, PubMed]; Plasma membrane Na(+)/H(+) antiporter. Mediates the electroneutral exchange of intracellular H(+) ions for extracellular Na(+) in 1:1 stoichiometry. Responsible for regulating intracellular pH homeostasis, in particular in neural tissues (PubMed:9933642). Acts as a negative regulator of dendritic spine growth. Plays a role in postsynaptic remodeling and signaling. Can also contribute to organellar pH regulation, with consequences for receptor tyrosine kinase trafficking (By similarity)., [UniProtKB, UniProtKB, PubMed]; These data suggest that NHE1, but not NHE5, plays an important role reducing inflammatory pain in rats., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 1, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "G3V9Y4", "ec_number_list": "", "go_molecular_function": "GO:0015385 sodium:proton antiporter activity;GO:0015386 potassium:proton antiporter activity;GO:1990763 arrestin family protein binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005925 focal adhesion;GO:0045202 synapse;GO:0055038 recycling endosome membrane;GO:0032591 dendritic spine membrane", "go_biological_process": "GO:0035725 sodium ion transmembrane transport;GO:0006814 sodium ion transport;GO:0051453 regulation of intracellular pH;GO:0071805 potassium ion transmembrane transport;GO:1902600 proton transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9Z0X2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9Z143-1", "uniprot_id": "SEM4F_RAT", "mass": 84298.0, "length": 776, "protein_name": "Semaphorin-4F", "gene_name": "Sema4f", "organism": "Rat", "refseq_name": "semaphorin-4F precursor", "refseq_ac": "NP_062145", "gene_names_uniprotkb": "Sema4f", "gene_names_refseq": "Sema4f", "protein_names_uniprotkb": "Semaphorin-4F; Sema W; Semaphorin-W", "protein_names_refseq": "Sema W; sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F; semaphorin-4F precursor; semaphorin-W; ssemaphorin 4F", "tax_id": 10116, "disease": "", "pathway": " (rno:29745); (R-RNO-9696264)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10051670;11483650;21945643", "class_list": "", "function": "Probable cell surface receptor that regulates oligodendroglial precursor cell migration (By similarity). Might also regulate differentiation of oligodendroglial precursor cells (PubMed:21945643). Has growth cone collapse activity against retinal ganglion-cell axons (PubMed:10051670)., [UniProtKB, UniProtKB, PubMed, PubMed]; Probable cell surface receptor that regulates oligodendroglial precursor cell migration. Might also regulate differentiation of oligodendroglial precursor cells. Has growth cone collapse activity against retinal ganglion-cell axons., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030215 semaphorin receptor binding;GO:0038191 neuropilin binding;GO:0045499 chemorepellent activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030425 dendrite", "go_biological_process": "GO:0030335 positive regulation of cell migration;GO:0071526 semaphorin-plexin signaling pathway;GO:0001755 neural crest cell migration;GO:0050919 negative chemotaxis;GO:0007411 axon guidance", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9Z143-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9Z269-1", "uniprot_id": "VAPB_RAT", "mass": 26916.0, "length": 243, "protein_name": "Vesicle-associated membrane protein-associated protein B", "gene_name": "Vapb", "organism": "Rat", "refseq_name": "vesicle-associated membrane protein-associated protein B", "refseq_ac": "NP_068619", "gene_names_uniprotkb": "Vapb", "gene_names_refseq": "VAMP-B; VAP-B; Vapb", "protein_names_uniprotkb": "Vesicle-associated membrane protein-associated protein B; VAMP-B; VAMP-associated protein B; VAP-B", "protein_names_refseq": "VAMP (vesicle-associated membrane protein)-associated protein B and C; VAMP-associated protein B; vesicle-associated membrane protein, associated protein B and C; vesicle-associated membrane protein-associated protein B", "tax_id": 10116, "disease": "amyotrophic lateral sclerosis type 8 (Disease Ontology:DOID:0050752); autosomal dominant adult-onset proximal spinal muscular atrophy (Disease Ontology:DOID:0111194); spinal muscular atrophy (Disease Ontology:DOID:12377); neurodegenerative disease (Disease Ontology:DOID:1289); motor neuron disease (Disease Ontology:DOID:231); amyotrophic lateral sclerosis (Disease Ontology:DOID:332)", "pathway": " (rno:60431); (R-RNO-8980692); (R-RNO-9013106); (R-RNO-9013404); (R-RNO-9013408)", "pathway_count": 5, "publication_count": 4, "publication_id_list": "22673903;23736259;30841933;9920726", "class_list": "", "function": "Endoplasmic reticulum (ER)-anchored protein that mediates the formation of contact sites between the ER and endosomes via interaction with FFAT motif-containing proteins such as STARD3 or WDR44. Interacts with STARD3 in a FFAT motif phosphorylation dependent manner. Via interaction with WDR44 participates in neosynthesized protein export. Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; VAPB-PTPIP51 mitochondrial tethering proteins are present in synapses and regulate synaptic activity. Publication Status: Online-Only, [RefSeq, PubMed]; YIF1A interacts with VAPB via its transmembrane regions, recycles between the ER and Golgi and is mainly localized to the ER-Golgi intermediate compartments in hippocampal neurons., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008017 microtubule binding;GO:0019899 enzyme binding;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0043495 protein-membrane adaptor activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane", "go_biological_process": "GO:0044790 suppression of viral release by host;GO:0044829 host-mediated activation of viral genome replication;GO:0090158 endoplasmic reticulum membrane organization;GO:0046725 negative regulation by virus of viral protein levels in host cell;GO:0036498 IRE1-mediated unfolded protein response", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9Z269-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9Z2I6-1", "uniprot_id": "SV2C_RAT", "mass": 82249.0, "length": 727, "protein_name": "Synaptic vesicle glycoprotein 2C", "gene_name": "Sv2c", "organism": "Rat", "refseq_name": "synaptic vesicle glycoprotein 2C", "refseq_ac": "NP_113781", "gene_names_uniprotkb": "Sv2c", "gene_names_refseq": "Sv2c", "protein_names_uniprotkb": "Synaptic vesicle glycoprotein 2C; Synaptic vesicle protein 2C", "protein_names_refseq": "synaptic vesicle glycoprotein 2C; synaptic vesicle protein 2C", "tax_id": 10116, "disease": "", "pathway": " (rno:29643)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10625067;15866046;16306227;16543415;18815274;19476346;19650874;21483489;21632541;27294781;9801366", "class_list": "", "function": "(Microbial infection) Possible receptor for C.botulinum neurotoxin type D (BoNT/D, botD); BoNT/D does not bind to extracellular loop 4 as do BoNT/A and BoNT/E (PubMed:21483489). Another group does not find a convincing interaction with SV2 (PubMed:21632541)., [UniProtKB, PubMed, PubMed]; (Microbial infection) Receptor for C.botulinum neurotoxin type A (BoNT/A, botA); the toxin binds Sv2c via extracellular loop 4 (PubMed:16543415, PubMed:27294781). Restores uptake of BoNT/A in rat cells that are deleted for SV2 receptor (PubMed:16543415, PubMed:18815274)., [UniProtKB, PubMed, PubMed, PubMed]; (Microbial infection) Receptor for C.botulinum neurotoxin type F (BoNT/F); binding requires glycosylation of Asn-573 (PubMed:19476346, PubMed:19650874)., [UniProtKB, PubMed, PubMed]; Findings show that botulinum neurotoxin (BoNT/A) enters neurons by binding to the synaptic vesicle protein SV2 (isoforms A, B, and C);SV2 acts as the protein receptor for BoNT/A, [RefSeq, PubMed]; Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles., [UniProtKB, PubMed, PubMed, UniProtKB, UniProtKB]; SV2-synaptotagmin interaction act in regulated exocytosis and SV2A and SV2C, via their additional synaptotagmin binding site, function differently than SV2B., [RefSeq, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0030672 synaptic vesicle membrane;GO:0008021 synaptic vesicle;GO:0098691 dopaminergic synapse", "go_biological_process": "GO:0007268 chemical synaptic transmission;GO:0090394 negative regulation of excitatory postsynaptic potential;GO:0006836 neurotransmitter transport;GO:2000300 regulation of synaptic vesicle exocytosis", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9Z2I6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9Z2K3-1", "uniprot_id": "ZN394_RAT", "mass": 60987.0, "length": 536, "protein_name": "Zinc finger protein 394", "gene_name": "Znf394", "organism": "Rat", "refseq_name": "zinc finger protein 394", "refseq_ac": "NP_663776", "gene_names_uniprotkb": "Znf394; Rlzfy; Zfp394; Zfp94; Zfp99", "gene_names_refseq": "Rlzfy; Zfp394; Zfp99; Zkscan14; Znf394", "protein_names_uniprotkb": "Zinc finger protein 394; RLZF-Y; Zfp-94; Zinc finger protein 94; Zinc finger protein Y1", "protein_names_refseq": "zfp-94; zinc finger protein 394; zinc finger protein 94; zinc finger protein 99; zinc finger protein Y1 (RLZF-Y); zinc finger with KRAB and SCAN domains 14", "tax_id": 10116, "disease": "", "pathway": " (rno:252860); (R-RNO-212436)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "9804994", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9Z2K3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9Z335-1", "uniprot_id": "SBK1_RAT", "mass": 45676.0, "length": 417, "protein_name": "Serine/threonine-protein kinase SBK1", "gene_name": "Sbk1", "organism": "Rat", "refseq_name": "serine/threonine-protein kinase SBK1", "refseq_ac": "NP_671476", "gene_names_uniprotkb": "Sbk1; Sbk", "gene_names_refseq": "Sbk1; Sbk", "protein_names_uniprotkb": "Serine/threonine-protein kinase SBK1; 2.7.11.1; SH3 domain-binding kinase 1", "protein_names_refseq": "SH3-binding domain kinase 1; SH3-binding kinase 1; serine/threonine-protein kinase SBK1", "tax_id": 10116, "disease": "", "pathway": " (rno:113907)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "11322885", "class_list": "", "function": "May be involved in signal-transduction pathways related to the control of brain development., [UniProtKB, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A2RRT7", "ec_number_list": "2.7.11.1;2.7.12.1;2.7.1.153;2.7.1.137;2.7.11.24;2.7.11.25;2.7.11.22;2.7.11.23;2.7.4.6;2.7.1.154;2.7.11.38;2.7.11.17;2.7.11.21;2.7.12.2;2.7.1.40;2.7.11.12;2.7.11.26;2.7.11.34;2.7.10.2;2.7.1.150;2.7.11.13;4.1.1.32;2.7.11.19;2.7.2.3;2.7.11.11;2.7.11.31;3.1.3.16;2.7.11.4;2.3.1.48;3.1.11.-;2.7.13.3;2.7.4.18;3.1.24.-;3.4.19.12;2.7.11.39;2.4.99.18;2.7.11.10", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0018107 peptidyl-threonine phosphorylation;GO:0018105 peptidyl-serine phosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9Z335-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A096MJA5-1", "uniprot_id": "A0A096MJA5_RAT", "mass": 33024.0, "length": 292, "protein_name": "Zygote arrest 1-like", "gene_name": "Zar1l", "organism": "Rat", "refseq_name": "protein ZAR1-like isoform X2", "refseq_ac": "XP_038945814", "gene_names_uniprotkb": "Zar1l", "gene_names_refseq": "Zar1l", "protein_names_uniprotkb": "Zygote arrest 1-like", "protein_names_refseq": "protein ZAR1-like isoform X2", "tax_id": 10116, "disease": "", "pathway": " (rno:689594)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "mRNA-binding protein required for maternal mRNA storage, translation and degradation during oocyte maturation. Probably promotes formation of some phase-separated membraneless compartment that stores maternal mRNAs in oocytes: acts by undergoing liquid-liquid phase separation upon binding to maternal mRNAs. Binds to the 3'-UTR of maternal mRNAs, inhibiting their translation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003730 mRNA 3'-UTR binding;GO:0003729 mRNA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0036464 cytoplasmic ribonucleoprotein granule", "go_biological_process": "GO:0017148 negative regulation of translation;GO:0001556 oocyte maturation;GO:0048477 oogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A096MJA5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A096MJF9-1", "uniprot_id": "A0A096MJF9_RAT", "mass": 116387.0, "length": 1073, "protein_name": "Transmembrane protein 132E", "gene_name": "Tmem132e", "organism": "Rat", "refseq_name": "transmembrane protein 132E precursor", "refseq_ac": "NP_001401263", "gene_names_uniprotkb": "Tmem132e", "gene_names_refseq": "RGD1565522; Tmem132e", "protein_names_uniprotkb": "Transmembrane protein 132E", "protein_names_refseq": "transmembrane protein 132E precursor", "tax_id": 10116, "disease": "autosomal recessive nonsyndromic deafness 99 (Disease Ontology:DOID:0111634)", "pathway": " (rno:287564)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, 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"Astn2", "organism": "Rat", "refseq_name": "astrotactin-2 isoform X2", "refseq_ac": "XP_017448601", "gene_names_uniprotkb": "Astn2", "gene_names_refseq": "Astn2", "protein_names_uniprotkb": "Astrotactin-2", "protein_names_refseq": "astrotactin-2 isoform X2", "tax_id": 10116, "disease": "", "pathway": " (rno:100361323)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "38843836", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005768 endosome;GO:0005769 early endosome;GO:0005938 cell cortex;GO:0016020 membrane;GO:0043204 perikaryon", "go_biological_process": "GO:0015031 protein transport;GO:0001764 neuron migration;GO:0007158 neuron cell-cell adhesion;GO:2000009 negative regulation of protein localization to cell surface;GO:0048105 establishment of body hair planar orientation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2JYU3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A096MK07-1", "uniprot_id": "A0A096MK07_RAT", "mass": 140254.0, "length": 1247, "protein_name": "Uncharacterized protein", "gene_name": "AC118772.1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "AC118772.1", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, 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"A0A096MKC0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A096MKH3-1", "uniprot_id": "A0A096MKH3_RAT", "mass": 99532.0, "length": 872, "protein_name": "Multiple C2 and transmembrane domain-containing protein 2", "gene_name": "Mctp2", "organism": "Rat", "refseq_name": "multiple C2 and transmembrane domain-containing protein 2", "refseq_ac": "NP_001178554", "gene_names_uniprotkb": "Mctp2", "gene_names_refseq": "Mctp2; RGD1562967", "protein_names_uniprotkb": "Multiple C2 and transmembrane domain-containing protein 2", "protein_names_refseq": "multiple C2 and transmembrane domain-containing protein 2; multiple C2 domains, transmembrane 2", "tax_id": 10116, "disease": "", "pathway": " (rno:308742)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Might play a role in the development of cardiac outflow tract., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0016020 membrane;GO:0030672 synaptic vesicle membrane", "go_biological_process": "GO:0046928 regulation of neurotransmitter secretion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A096MKH3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A096UWG9-1", "uniprot_id": "A0A096UWG9_RAT", "mass": 63960.0, "length": 567, "protein_name": "Diacylglycerol kinase", "gene_name": "Dgke", "organism": "Rat", "refseq_name": "diacylglycerol kinase epsilon isoform 1", "refseq_ac": "NP_001381287", "gene_names_uniprotkb": "Dgke", "gene_names_refseq": "Dgke", "protein_names_uniprotkb": "Diacylglycerol kinase; 2.7.1.107; DAG kinase", "protein_names_refseq": "diacylglycerol kinase epsilon isoform 1; diacylglycerol kinase, epsilon 64kDa", "tax_id": 10116, "disease": "nephrotic syndrome type 7 (Disease Ontology:DOID:0080388)", "pathway": " (rno:497978); (R-RNO-114508)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "18487437;19421779;23467923;28191598", "class_list": "", "function": "DGKepsilon interacts with actin stress fibers and is involved in their stability in vascular smooth muscle cells., [RefSeq, PubMed]; Diacylglycerol kinase-epsilon restores cardiac dysfunction under chronic pressure overload: a new specific regulator of Galpha(q) signaling cascade., [RefSeq, PubMed]; Findings suggest that DGKepsilon plays an important role in neuronal and brain functions through its distinct neuronal expression and subcellular localization and also through coordinated arrangement with other molecules involving the phosphoinositide signaling pathway, [RefSeq, PubMed]; Membrane-bound diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes. Also plays an important role in the biosynthesis of complex lipids. Displays specificity for diacylglycerol substrates with an arachidonoyl acyl chain at the sn-2 position, with the highest activity toward 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol the main diacylglycerol intermediate within the phosphatidylinositol turnover cycle. Can also phosphorylate diacylglycerol substrates with a linoleoyl acyl chain at the sn-2 position but much less efficiently., [UniProtKB, UniProtKB]; The DGKepsilon is evident in the outer limiting membrane., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.1.107;2.7.1.94;2.7.1.138;2.7.1.93", "go_molecular_function": "GO:0004143 ATP-dependent diacylglycerol kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0016301 kinase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0046339 diacylglycerol metabolic process;GO:0046834 lipid phosphorylation;GO:0006654 phosphatidic acid biosynthetic process;GO:0035556 intracellular signal transduction;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A096UWG9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2JST1-1", "uniprot_id": "A0A0G2JST1_RAT", "mass": 139253.0, "length": 1248, "protein_name": "Adhesion G-protein coupled receptor G6", "gene_name": "Adgrg6", "organism": "Rat", "refseq_name": "adhesion G-protein coupled receptor G6 isoform X1", "refseq_ac": "XP_218313", "gene_names_uniprotkb": "Adgrg6", "gene_names_refseq": "Adgrg6; Gpr126", "protein_names_uniprotkb": "Adhesion G-protein coupled receptor G6; Developmentally regulated G-protein-coupled receptor; G-protein coupled receptor 126", "protein_names_refseq": "adhesion G-protein coupled receptor G6 isoform X1", "tax_id": 10116, "disease": "idiopathic scoliosis (Disease Ontology:DOID:0060250); lethal congenital contracture syndrome (Disease Ontology:DOID:0060558)", "pathway": " (R-RNO-9619665)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16641100", "class_list": "", "function": "Adhesion G-protein coupled receptor (aGPCR) for steroid hormones, such as progesterone and 17alpha-hydroxyprogesterone (17OHP). Involved in many biological processes, such as myelination, sprouting angiogenesis, placenta, ear and cartilage development. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. ADGRG6 is coupled to G(i) G alpha proteins and mediates inhibition of adenylate cyclase. Also able to couple to G(q) G proteins. Involved in myelination of the peripheral nervous system: required for differentiation of promyelinating Schwann cells and for normal myelination of axons. Also acts as a regulator of body length and bone mass. Acts as a regulator of blood-brain barrier formation in the central nervous system vie its association with LRP1 and ITGB1., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0046872 metal ion binding;GO:0043236 laminin binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005737 cytoplasm;GO:0009986 cell surface", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0022011 myelination in peripheral nervous system;GO:0060347 heart trabecula formation;GO:0060856 establishment of blood-brain barrier", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JST1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2JT90-1", "uniprot_id": "A0A0G2JT90_RAT", "mass": 68685.0, "length": 629, "protein_name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "gene_name": "Ash2l", "organism": "Rat", "refseq_name": "set1/Ash2 histone methyltransferase complex subunit ASH2 isoform X1", "refseq_ac": "XP_006253365", "gene_names_uniprotkb": "Ash2l", "gene_names_refseq": "Ash2l", "protein_names_uniprotkb": "Set1/Ash2 histone methyltransferase complex subunit ASH2; ASH2-like protein", "protein_names_refseq": "set1/Ash2 histone methyltransferase complex subunit ASH2 isoform X1", "tax_id": 10116, "disease": "congenital heart disease (Disease Ontology:DOID:1682); schizophrenia (Disease Ontology:DOID:5419)", "pathway": " (rno:290829); (R-RNO-201722); (R-RNO-3214841); (R-RNO-3769402); (R-RNO-8936459); (R-RNO-9772755); (R-RNO-9909649)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Transcriptional regulator. Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters. Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May play a role in hematopoiesis. In association with RBBP5 and WDR5, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000976 transcription cis-regulatory region binding;GO:0008013 beta-catenin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005886 plasma membrane;GO:0035097 histone methyltransferase complex;GO:0000791 euchromatin", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006974 DNA damage response;GO:0045815 transcription initiation-coupled chromatin remodeling;GO:0043627 response to estrogen", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JT90-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2JTI5-1", "uniprot_id": "A0A0G2JTI5_RAT", "mass": 67787.0, "length": 605, "protein_name": "Ral GEF with PH domain and SH3 binding motif 2", "gene_name": "Ralgps2", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Ralgps2", "gene_names_refseq": "", "protein_names_uniprotkb": "Ral GEF with PH domain and SH3 binding motif 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0007264 small GTPase-mediated signal transduction;GO:0032485 regulation of Ral protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JTI5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2JTM6-1", "uniprot_id": "A0A0G2JTM6_RAT", "mass": 78759.0, "length": 703, "protein_name": "Probable ATP-dependent RNA helicase DHX35", "gene_name": "Dhx35", "organism": "Rat", "refseq_name": "probable ATP-dependent RNA helicase DHX35 isoform 1", "refseq_ac": "NP_001402786", "gene_names_uniprotkb": "Dhx35", "gene_names_refseq": "Dhx35", "protein_names_uniprotkb": "Probable ATP-dependent RNA helicase DHX35; 3.6.4.13; DEAH box protein 35", "protein_names_refseq": "DEAH (Asp-Glu-Ala-His) box polypeptide 35; probable ATP-dependent RNA helicase DHX35 isoform 1; probable ATP-dependent RNA helicase DHX35", "tax_id": 10116, "disease": "", "pathway": " (rno:362260); (R-RNO-72163)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "May be involved in pre-mRNA splicing., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.6.2.3;3.6.4.13;3.6.4.12;2.7.11.1;3.6.1.5;3.6.4.10;3.6.4.-;2.3.2.27;5.6.2.4;5.2.1.8;3.6.5.-;5.6.2.-;3.1.-.-;2.7.7.6;2.7.7.7;2.7.7.49;3.1.13.1;4.2.99.18;7.6.2.2;7.6.2.3;7.6.2.-;5.6.1.6;7.2.2.-;3.6.1.15;3.6.4.6;3.1.3.1;3.9.1.1;6.1.1.12;3.6.1.-;2.7.4.3;3.1.4.-;3.4.24.-;3.6.-.-;3.4.21.53;5.6.2.5", "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0004386 helicase activity;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:0071013 catalytic step 2 spliceosome", "go_biological_process": "GO:0001701 in utero embryonic development;GO:0006397 mRNA processing;GO:0008380 RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JTM6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2JTX7-1", "uniprot_id": "A0A0G2JTX7_RAT", "mass": 289291.0, "length": 2635, "protein_name": "Collagen alpha-5(VI) chain", "gene_name": "Col6a5", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Col6a5", "gene_names_refseq": "", "protein_names_uniprotkb": "Collagen alpha-5(VI) chain; Collagen alpha-1(XXIX) chain", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:501047); (R-RNO-1650814)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Collagen VI acts as a cell-binding protein., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0031012 extracellular matrix;GO:0005589 collagen type VI trimer", "go_biological_process": "GO:0007155 cell adhesion;GO:0030198 extracellular matrix organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JTX7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2JTY3-1", "uniprot_id": "A0A0G2JTY3_RAT", "mass": 48894.0, "length": 455, "protein_name": "Solute carrier family 37 member 4", "gene_name": "Slc37a4", "organism": "Rat", "refseq_name": "glucose-6-phosphate exchanger SLC37A4 isoform X1", "refseq_ac": "XP_008764373", "gene_names_uniprotkb": "Slc37a4", "gene_names_refseq": "G6pt1; 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2.7.12.1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:312721)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Possible non-essential role in spermiogenesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.12.1;2.7.10.1;2.7.1.153;2.7.1.137;2.7.10.2;2.7.11.24;2.7.11.25;2.7.11.22;2.7.11.23;2.7.4.6;2.7.1.154;2.7.11.38;2.7.11.17;2.7.11.21;2.7.12.2;2.7.1.40;2.7.11.12;2.7.11.26;2.7.11.34;2.7.1.150;2.7.11.13;4.1.1.32;2.7.11.19;2.7.2.3;2.7.11.11;2.7.10.4;2.7.11.31;3.1.3.16;2.7.11.4;2.3.1.48;2.7.1.32;2.7.1.82;3.1.11.-;2.7.13.3;2.7.4.18;3.1.24.-;3.4.19.12;2.7.11.39;2.4.99.18;2.7.11.10", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004712 protein serine/threonine/tyrosine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005634 nucleus;GO:0005856 cytoskeleton", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JU41-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2JU49-1", "uniprot_id": "A0A0G2JU49_RAT", "mass": 52989.0, "length": 472, "protein_name": "Metaxin-1", "gene_name": "Mtx1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Mtx1", "gene_names_refseq": "", "protein_names_uniprotkb": "Metaxin-1; 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Essential for embryonic development., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0001401 SAM complex", "go_biological_process": "GO:0045040 protein insertion into mitochondrial outer membrane;GO:0015031 protein transport;GO:0007595 lactation;GO:0070096 mitochondrial outer membrane translocase complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JU49-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2JUG5-1", "uniprot_id": "A0A0G2JUG5_RAT", "mass": 34404.0, "length": 310, "protein_name": "Olfactory receptor", "gene_name": "Or5p80", "organism": "Rat", "refseq_name": "olfactory receptor family 5 subfamily P member 80", "refseq_ac": "NP_001396077", "gene_names_uniprotkb": "Or5p80; 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PAS domain containing repressor 1 isoform 1; circadian clock protein PASD1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0140416 transcription regulator inhibitor activity;GO:0140297 DNA-binding transcription factor binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:1990513 CLOCK-BMAL transcription complex;GO:1990512 Cry-Per complex;GO:0005634 nucleus;GO:0016607 nuclear speck", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription;GO:0032922 circadian regulation of gene expression;GO:0042754 negative regulation of circadian rhythm", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JVM9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2JVP5-1", "uniprot_id": "A0A0G2JVP5_RAT", "mass": 58627.0, "length": 526, "protein_name": "Polyadenylate-binding protein-interacting protein 1", "gene_name": "Paip1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Paip1", "gene_names_refseq": "", "protein_names_uniprotkb": "Polyadenylate-binding protein-interacting protein 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-429947)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0008494 translation activator activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0106002 mCRD-mediated mRNA stability complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0070934 CRD-mediated mRNA stabilization;GO:2000767 positive regulation of cytoplasmic translation;GO:0006446 regulation of translational initiation;GO:0044794 host-mediated activation of viral process;GO:1900152 negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JVP5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2JVP8-1", "uniprot_id": "A0A0G2JVP8_RAT", "mass": 54003.0, "length": 469, "protein_name": "Cytosolic beta-glucosidase", "gene_name": "Gba3", "organism": "Rat", "refseq_name": "glucosylceramidase beta 3", "refseq_ac": "NP_001382556", "gene_names_uniprotkb": "Gba3", "gene_names_refseq": "Gba3", "protein_names_uniprotkb": "Cytosolic beta-glucosidase; 3.2.1.21; 3.2.1.45; 3.2.1.46; Cytosolic galactosylceramidase; Cytosolic glucosylceramidase; Cytosolic glycosylceramidase", "protein_names_refseq": "cytosolic beta-glucosidase; glucosidase, beta, acid 3 (cytosolic); glucosylceramidase beta 3", "tax_id": 10116, "disease": "kidney disease (Disease Ontology:DOID:557)", "pathway": " (rno:289687); (R-RNO-9840310)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.2.1.45;3.2.1.21;3.2.1.46;2.4.1.-;3.2.1.-", "go_molecular_function": "GO:0004348 glucosylceramidase activity;GO:0017042 glycosylceramidase activity;GO:0008422 beta-glucosidase activity;GO:0004565 beta-galactosidase activity;GO:0004336 galactosylceramidase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0016020 membrane;GO:1902494 catalytic complex", "go_biological_process": "GO:0006680 glucosylceramide catabolic process;GO:0050821 protein stabilization;GO:0016139 glycoside catabolic process;GO:0046477 glycosylceramide catabolic process;GO:0006683 galactosylceramide catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JVP8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2JVR1-1", "uniprot_id": "A0A0G2JVR1_RAT", "mass": 32560.0, "length": 276, "protein_name": "Ly49 stimulatory receptor 4", "gene_name": "Ly49s4", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Ly49s4", "gene_names_refseq": "", "protein_names_uniprotkb": "Ly49 stimulatory receptor 4", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030246 carbohydrate binding;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0007155 cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JVR1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2JW23-1", "uniprot_id": "A0A0G2JW23_RAT", "mass": 119267.0, "length": 1054, "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "Nlrp12", "organism": "Rat", "refseq_name": "NACHT, LRR and PYD domains-containing protein 12", "refseq_ac": "NP_001162613", "gene_names_uniprotkb": "Nlrp12", "gene_names_refseq": "Nalp12; Nlrp12", "protein_names_uniprotkb": "NACHT, LRR and PYD domains-containing protein 12; Monarch-1; PYRIN-containing APAF1-like protein 7", "protein_names_refseq": "NACHT, LRR and PYD domains-containing protein 12; NACHT, leucine rich repeat and PYD containing 12", "tax_id": 10116, "disease": "familial cold autoinflammatory syndrome 2 (Disease Ontology:DOID:0090063)", "pathway": " (rno:292541)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays an essential role as an potent mitigator of inflammation. Primarily expressed in dendritic cells and macrophages, inhibits both canonical and non-canonical NF-kappa-B and ERK activation pathways. Functions as a negative regulator of NOD2 by targeting it to degradation via the proteasome pathway. In turn, promotes bacterial tolerance. Also inhibits the RIGI-mediated immune signaling against RNA viruses by reducing the E3 ubiquitin ligase TRIM25-mediated 'Lys-63'-linked RIGI activation but enhancing the E3 ubiquitin ligase RNF125-mediated 'Lys-48'-linked RIGI degradation. Also acts as a negative regulator of inflammatory response to mitigate obesity and obesity-associated diseases in adipose tissue., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0061702 canonical inflammasome complex", "go_biological_process": "GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction;GO:0032715 negative regulation of interleukin-6 production;GO:0050728 negative regulation of inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JW23-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2JW59-1", "uniprot_id": "A0A0G2JW59_RAT", "mass": 114249.0, "length": 1005, "protein_name": "Receptor-type tyrosine-protein kinase FLT3", "gene_name": "Flt3", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Flt3", "gene_names_refseq": "", "protein_names_uniprotkb": "Receptor-type tyrosine-protein kinase FLT3; 2.7.10.1; FL cytokine receptor; Fms-like tyrosine kinase 3", "protein_names_refseq": "", "tax_id": 10116, "disease": "juvenile myelomonocytic leukemia (Disease Ontology:DOID:0050458); colorectal adenocarcinoma (Disease Ontology:DOID:0050861); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); B-lymphoblastic leukemia/lymphoma (Disease Ontology:DOID:0080630); acute myelomonocytic leukemia (Disease Ontology:DOID:0081082); prostate cancer (Disease Ontology:DOID:10283); myelofibrosis (Disease Ontology:DOID:4971); hepatocellular carcinoma (Disease Ontology:DOID:684); acute myeloid leukemia (Disease Ontology:DOID:9119); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (rno:140635); (R-RNO-109704); (R-RNO-1257604); (R-RNO-5673001); (R-RNO-6811558); (R-RNO-9607240)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Tyrosine-protein kinase that acts as a cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Promotes phosphorylation of FES, FER, PTPN6/SHP, PTPN11/SHP-2, PLCG1, and STAT5A and/or STAT5B. Activation of wild-type FLT3 causes only marginal activation of STAT5A or STAT5B. Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.12.1;2.7.10.1;2.7.11.1;2.7.1.153;2.7.1.137;2.7.10.2;2.7.1.154;2.7.12.2;2.7.1.40;2.3.2.27;3.6.5.2;2.7.11.17;2.7.11.13;2.7.10.4;3.1.3.48;2.7.1.32;2.7.1.82;3.2.2.6;2.7.11.23;3.2.1.31", "go_molecular_function": "GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0019838 growth factor binding;GO:0046872 metal ion binding;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0043235 receptor complex;GO:0009897 external side of plasma membrane;GO:0032991 protein-containing complex", "go_biological_process": "GO:0002318 myeloid progenitor cell differentiation;GO:0032727 positive regulation of interferon-alpha production;GO:0002328 pro-B cell differentiation;GO:0036145 dendritic cell homeostasis;GO:0001934 positive regulation of protein phosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JW59-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2JW96-1", "uniprot_id": "A0A0G2JW96_RAT", "mass": 70511.0, "length": 616, "protein_name": "Zinc finger protein 94 like 1", "gene_name": "Zfp94l1", "organism": "Rat", "refseq_name": "zinc finger protein 45", "refseq_ac": "XP_063133704", "gene_names_uniprotkb": "Zfp94l1; LOC102548695", "gene_names_refseq": "Zfp94l1", "protein_names_uniprotkb": "Zinc finger protein 94 like 1", "protein_names_refseq": "zinc finger protein 45", "tax_id": 10116, "disease": "", "pathway": " (rno:102548695); (R-RNO-212436)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000976 transcription cis-regulatory region binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JW96-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2JWC5-1", "uniprot_id": "A0A0G2JWC5_RAT", "mass": 59739.0, "length": 536, "protein_name": "Testis-expressed protein 13D-like", "gene_name": "LOC134484021", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LOC134484021", "gene_names_refseq": "", "protein_names_uniprotkb": "Testis-expressed protein 13D-like", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:134484021)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JWC5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2JWQ0-1", "uniprot_id": "A0A0G2JWQ0_RAT", "mass": 61819.0, "length": 547, "protein_name": "General transcription factor IIH subunit 1", "gene_name": "Gtf2h1", "organism": "Rat", "refseq_name": "general transcription factor IIH subunit 1", "refseq_ac": "NP_001386573", "gene_names_uniprotkb": "Gtf2h1", "gene_names_refseq": "Gtf2h1", "protein_names_uniprotkb": "General transcription factor IIH subunit 1; Basic transcription factor 2 62 kDa subunit; General transcription factor IIH polypeptide 1; TFIIH basal transcription factor complex p62 subunit", "protein_names_refseq": "general transcription factor IIH subunit 1; general transcription factor IIH, polypeptide 1", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-112382); (R-RNO-113418); (R-RNO-5696395); (R-RNO-5696400); (R-RNO-674695); (R-RNO-6781823); (R-RNO-6782135); (R-RNO-6782210); (R-RNO-6796648); (R-RNO-72086); (R-RNO-73762); (R-RNO-73772); (R-RNO-73776); (R-RNO-73779); (R-RNO-73863); (R-RNO-75953); (R-RNO-75955); (R-RNO-76042); (R-RNO-77075)", "pathway_count": 19, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0046966 nuclear thyroid hormone receptor binding", "go_cellular_component": "GO:0005675 transcription factor TFIIH holo complex;GO:0000439 transcription factor TFIIH core complex;GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006360 transcription by RNA polymerase I;GO:0006281 DNA repair;GO:0006366 transcription by RNA polymerase II;GO:0006289 nucleotide-excision repair;GO:1990830 cellular response to leukemia inhibitory factor", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JWQ0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2JWZ0-1", "uniprot_id": "A0A0G2JWZ0_RAT", "mass": 9042.0, "length": 79, "protein_name": "Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit TMEM258", "gene_name": "Tmem258l4", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Tmem258l4; AABR07040624.1", "gene_names_refseq": "", "protein_names_uniprotkb": "Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit TMEM258; Transmembrane protein 258", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:680191)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0062062 oligosaccharyltransferase complex binding", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0008250 oligosaccharyltransferase complex", "go_biological_process": "GO:0006487 protein N-linked glycosylation;GO:0034976 response to endoplasmic reticulum stress", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JWZ0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2JX27-1", "uniprot_id": "A0A0G2JX27_RAT", "mass": 76671.0, "length": 700, "protein_name": "Leishmanolysin-like peptidase", "gene_name": "Cirop", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Cirop", "gene_names_refseq": "", "protein_names_uniprotkb": "Leishmanolysin-like peptidase; 3.4.24.-", "protein_names_refseq": "", "tax_id": 10116, "disease": "visceral heterotaxy 12 (Disease Ontology:DOID:0051026)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Putative metalloproteinase that plays a role in left-right patterning process., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding;GO:0008233 peptidase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0007155 cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JX27-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2JX78-1", "uniprot_id": "A0A0G2JX78_RAT", "mass": 71965.0, "length": 632, "protein_name": "5'-nucleotidase, cytosolic IB", "gene_name": "Nt5c1b", "organism": "Rat", "refseq_name": "cytosolic 5'-nucleotidase 1B isoform X1", "refseq_ac": "XP_006239950", "gene_names_uniprotkb": "Nt5c1b", "gene_names_refseq": "Nt5c1b; Rdh14", "protein_names_uniprotkb": "5'-nucleotidase, cytosolic IB", "protein_names_refseq": "cytosolic 5'-nucleotidase 1B isoform X1", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-74259)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0000166 nucleotide binding;GO:0008253 5'-nucleotidase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0046085 adenosine metabolic process;GO:0006196 AMP catabolic process;GO:0009116 nucleoside metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JX78-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2JXE3-1", "uniprot_id": "A0A0G2JXE3_RAT", "mass": 19069.0, "length": 166, "protein_name": "Uncharacterized protein", "gene_name": "AABR07026557.1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "AABR07026557.1", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0001669 acrosomal vesicle", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JXE3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2JXG9-1", "uniprot_id": "A0A0G2JXG9_RAT", "mass": 35906.0, "length": 321, "protein_name": "Olfactory receptor", "gene_name": "Or7g17", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Or7g17", "gene_names_refseq": "", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JXG9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2JXT9-1", "uniprot_id": "A0A0G2JXT9_RAT", "mass": 222093.0, "length": 2057, "protein_name": "Rho guanine nucleotide exchange factor 17", "gene_name": "Arhgef17", "organism": "Rat", "refseq_name": "rho guanine nucleotide exchange factor 17", "refseq_ac": "NP_001388752", "gene_names_uniprotkb": "Arhgef17", "gene_names_refseq": "Arhgef17", "protein_names_uniprotkb": "Rho guanine nucleotide exchange factor 17", "protein_names_refseq": "Rho guanine nucleotide exchange factor (GEF) 17; rho guanine nucleotide exchange factor 17", "tax_id": 10116, "disease": "intracranial aneurysm (Disease Ontology:DOID:10941)", "pathway": " (rno:120099896); (R-RNO-193648); (R-RNO-416482); (R-RNO-8980692); (R-RNO-9013026); (R-RNO-9013106)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Acts as a guanine nucleotide exchange factor (GEF) for RhoA GTPases., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, 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May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. 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Part of chromatin remodeling machinery predominantly forms H3K4me1 methylation marks at active chromatin sites where transcription and DNA repair take place. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 13, "predicted_n_glycosites": 0, "predicted_o_glycosites": 13, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 16, "glyco_site_count": 13, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.1.1.364;2.1.1.370;2.1.1.371;2.3.1.48;2.1.1.-;2.1.1.85;2.1.1.359;2.1.1.355;2.1.1.354;2.1.1.362;2.1.1.361;2.1.1.319", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0008270 zinc ion binding;GO:0000976 transcription cis-regulatory region binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0042800 histone H3K4 methyltransferase activity", "go_cellular_component": "GO:0044666 MLL3/4 complex;GO:0035097 histone methyltransferase complex", "go_biological_process": "GO:0001701 in utero embryonic development;GO:0006351 DNA-templated transcription;GO:0008284 positive regulation of cell population proliferation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0043627 response to estrogen", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JVD6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A096MJ91-1", "uniprot_id": "A0A096MJ91_RAT", "mass": 186333.0, "length": 1670, "protein_name": "Phosphoinositide phospholipase C", "gene_name": "Plch1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Plch1", "gene_names_refseq": "", "protein_names_uniprotkb": "Phosphoinositide phospholipase C; 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Or8b37", "protein_names_uniprotkb": "Olfactory receptor family 8 subfamily B member 37", "protein_names_refseq": "olfactory receptor 1206; olfactory receptor Olr1206; olfactory receptor gene Olr1206", "tax_id": 10116, "disease": "", "pathway": " (rno:405103)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A096MK69-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2JUK2-1", "uniprot_id": "A0A0G2JUK2_RAT", "mass": 52196.0, "length": 477, "protein_name": "LSM14A mRNA processing body assembly factor", "gene_name": "Lsm14a", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Lsm14a", "gene_names_refseq": "", "protein_names_uniprotkb": "LSM14A mRNA processing body assembly factor", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:361554)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0003690 double-stranded DNA binding;GO:0003725 double-stranded RNA binding;GO:0003727 single-stranded RNA binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0000932 P-body;GO:0036464 cytoplasmic ribonucleoprotein granule;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0051607 defense response to virus;GO:0090307 mitotic spindle assembly;GO:0017148 negative regulation of translation;GO:0033962 P-body assembly;GO:0034063 stress granule assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2JUK2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K1Q8-1", "uniprot_id": "ABCA3_RAT", "mass": 191767.0, "length": 1704, "protein_name": "Phospholipid-transporting ATPase ABCA3", "gene_name": "Abca3", "organism": "Rat", "refseq_name": "phospholipid-transporting ATPase ABCA3", "refseq_ac": "NP_001382963", "gene_names_uniprotkb": "Abca3", "gene_names_refseq": "Abca3", "protein_names_uniprotkb": "Phospholipid-transporting ATPase ABCA3; 7.6.2.1; 7.6.2.2; ATP-binding cassette sub-family A member 3; Xenobiotic-transporting ATPase ABCA3", "protein_names_refseq": "ATP-binding cassette sub-family A member 3; ATP-binding cassette, sub-family A (ABC1), member 3; ATP-binding cassette, subfamily A (ABC1), member 3; phospholipid-transporting ATPase ABCA3; xenobiotic-transporting ATPase ABCA3", "tax_id": 10116, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041); neonatal respiratory failure (Disease Ontology:DOID:11161); respiratory failure (Disease Ontology:DOID:11162); pulmonary alveolar proteinosis (Disease Ontology:DOID:12120); newborn respiratory distress syndrome (Disease Ontology:DOID:12716); interstitial lung disease (Disease Ontology:DOID:3082); lung disease (Disease Ontology:DOID:850)", "pathway": " (rno:302973); (R-RNO-1369062); (R-RNO-5683826)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "11940594;15369786;38843836", "class_list": "", "function": "Catalyzes the ATP-dependent transport of phospholipids such as phosphatidylcholine and phosphoglycerol from the cytoplasm into the lumen side of lamellar bodies, in turn participates in the lamellar bodies biogenesis and homeostasis of pulmonary surfactant. Transports preferentially phosphatidylcholine containing short acyl chains. In addition plays a role as an efflux transporter of miltefosine across macrophage membranes and free cholesterol (FC) through intralumenal vesicles by removing FC from the cell as a component of surfactant and protects cells from free cholesterol toxicity., [UniProtKB, UniProtKB]; Identification of LBM180, a lamellar body limiting membrane protein of alveolar type II cells, as the ABC transporter protein ABCA3., [RefSeq, PubMed]; These findings demonstrate that glucocorticoid-induced up-regulation of ABCA3 expression in vivo is mediated by transcriptional activation through the GRE in the promoter., [RefSeq, PubMed]", "predicted_glycosites": 9, "predicted_n_glycosites": 8, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 7, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "7.6.2.1;7.6.2.2;7.6.2.-", "go_molecular_function": "GO:0005319 lipid transporter activity;GO:0005524 ATP binding;GO:0042626 ATPase-coupled transmembrane transporter activity;GO:0008559 ABC-type xenobiotic transporter activity;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005765 lysosomal membrane;GO:0030659 cytoplasmic vesicle membrane;GO:0005770 late endosome;GO:0097208 alveolar lamellar body", "go_biological_process": "GO:0032368 regulation of lipid transport;GO:0006869 lipid transport;GO:0010875 positive regulation of cholesterol efflux;GO:0043129 surfactant homeostasis;GO:0030324 lung development", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0G2K1Q8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZSP7-1", "uniprot_id": "TTC3_RAT", "mass": 225783.0, "length": 2000, "protein_name": "E3 ubiquitin-protein ligase TTC3", "gene_name": "Ttc3", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Ttc3", "gene_names_refseq": "", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase TTC3; 2.3.2.27; RING-type E3 ubiquitin transferase TTC3; TPR repeat protein D", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:360702)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "24695496", "class_list": "", "function": "E3 ubiquitin-protein ligase which catalyzes the formation of 'Lys-48'-polyubiquitin chains (By similarity). Mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus (By similarity). Acts as a terminal regulator of Akt signaling after activation; its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation (By similarity). Positively regulates TGFB1-induced epithelial-mesenchymal transition and myofibroblast differentiation by mediating the ubiquitination and subsequent degradation of SMURF2 (By similarity). Regulates neuronal differentiation by regulating actin remodeling and Golgi organization via a signaling cascade involving RHOA, CIT and ROCK (PubMed:24695496). Inhibits cell proliferation (By similarity)., [UniProtKB, PubMed, UniProtKB]; E3 ubiquitin-protein ligase which catalyzes the formation of 'Lys-48'-polyubiquitin chains. Mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation; its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Positively regulates TGFB1-induced epithelial-mesenchymal transition and myofibroblast differentiation by mediating the ubiquitination and subsequent degradation of SMURF2. Regulates neuronal differentiation by regulating actin remodeling and Golgi organization via a signaling cascade involving RHOA, CIT and ROCK. Inhibits cell proliferation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005794 Golgi apparatus;GO:0005773 vacuole;GO:0005737 cytoplasm", "go_biological_process": "GO:0006511 ubiquitin-dependent protein catabolic process;GO:0070936 protein K48-linked ubiquitination;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZSP7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A140UHX4-1", "uniprot_id": "A0A140UHX4_RAT", "mass": 63055.0, "length": 567, "protein_name": "Protein kinase AMP-activated non-catalytic subunit gamma 2", "gene_name": "Prkag2", "organism": "Rat", "refseq_name": "5'-AMP-activated protein kinase subunit gamma-2 isoform X5", "refseq_ac": "XP_006236013", "gene_names_uniprotkb": "Prkag2", "gene_names_refseq": "Prkag2", "protein_names_uniprotkb": "Protein kinase AMP-activated non-catalytic subunit gamma 2", "protein_names_refseq": "5'-AMP-activated protein kinase subunit gamma-2 isoform X5", "tax_id": 10116, "disease": "lethal congenital glycogen storage disease of heart (Disease Ontology:DOID:0090101); hypertrophic cardiomyopathy 6 (Disease Ontology:DOID:0110312); neurodegenerative disease (Disease Ontology:DOID:1289); glycogen storage disease (Disease Ontology:DOID:2747); Wolff-Parkinson-White syndrome (Disease Ontology:DOID:384)", "pathway": " (R-RNO-1632852); (R-RNO-163680); (R-RNO-200425); (R-RNO-380972); (R-RNO-5628897); (R-RNO-6804756); (R-RNO-9931269)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0019901 protein kinase binding;GO:0004862 cAMP-dependent protein kinase inhibitor activity;GO:0008603 cAMP-dependent protein kinase regulator activity;GO:0008607 phosphorylase kinase regulator activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0031588 nucleotide-activated protein kinase complex", "go_biological_process": "GO:0006633 fatty acid biosynthetic process;GO:0006110 regulation of glycolytic process;GO:0035556 intracellular signal transduction;GO:0005977 glycogen metabolic process;GO:0019217 regulation of fatty acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140UHX4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K9A4-1", "uniprot_id": "A0A0G2K9A4_RAT", "mass": 26554.0, "length": 239, "protein_name": "CT55", "gene_name": "LOC120099188; LOC120099189; LOC120099190; LOC120099287", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LOC120099188; LOC120099189; LOC120099190; LOC120099287; Ct55l1; LOC120099188; LOC120099189; LOC120099190; LOC120099191; LOC120099287", "gene_names_refseq": "", "protein_names_uniprotkb": "CT55", "protein_names_refseq": "", "tax_id": 10116, "disease": "X-linked spermatogenic failure 7 (Disease Ontology:DOID:0070598)", "pathway": " (rno:120099188); (rno:120099190); (rno:120099287)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A8I6AQ28", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K9A4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K8J8-1", "uniprot_id": "A0A0G2K8J8_RAT", "mass": 88899.0, "length": 789, "protein_name": "Constitutive coactivator of peroxisome proliferator-activated receptor gamma", "gene_name": "Fam120b", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Fam120b", "gene_names_refseq": "", "protein_names_uniprotkb": "Constitutive coactivator of peroxisome proliferator-activated receptor gamma; Protein FAM120B", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:308218)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Functions as a transactivator of PPARG and ESR1. 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Hence, the combinatorial expression of Kv1-associated CAMs may be critical to tune intrinsic excitability in physiological and epileptogenic contexts. 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Phospholipid translocation also seems to be implicated in vesicle formation and in uptake of lipid signaling molecules. May be responsible for the maintenance of asymmetric distribution of phosphatidylserine (PS) in spermatozoa membranes. 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Joubert syndrome (Disease Ontology:DOID:0050777); Meckel syndrome (Disease Ontology:DOID:0050778); ciliopathy (Disease Ontology:DOID:0060340); retinitis pigmentosa 93 (Disease Ontology:DOID:0061105); Meckel syndrome 6 (Disease Ontology:DOID:0070120); Joubert syndrome 9 (Disease Ontology:DOID:0111004); intellectual disability (Disease Ontology:DOID:1059)", "pathway": " (R-RNO-5620912)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0036038 MKS complex;GO:0035869 ciliary transition zone", "go_biological_process": "GO:0007507 heart development;GO:0001822 kidney development;GO:0001843 neural tube closure;GO:0060271 cilium assembly;GO:0007368 determination of left/right symmetry", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K9D9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZG06-1", "uniprot_id": "D3ZG06_RAT", "mass": 106920.0, "length": 966, "protein_name": "TBC1 domain family member 30", "gene_name": "Tbc1d30", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Tbc1d30", "gene_names_refseq": "", "protein_names_uniprotkb": "TBC1 domain family member 30", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:299824)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May act as a GTPase-activating protein for Rab family protein(s)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005929 cilium;GO:0036064 ciliary basal body", "go_biological_process": "GO:1902018 negative regulation of cilium assembly;GO:0043547 positive regulation of GTPase activity", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZG06-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZJT9-1", "uniprot_id": "D3ZJT9_RAT", "mass": 97411.0, "length": 868, "protein_name": "L3MBTL histone methyl-lysine binding protein 3", "gene_name": "L3mbtl3", "organism": "Rat", "refseq_name": "lethal(3)malignant brain tumor-like protein 3 isoform a", "refseq_ac": "NP_001419245", "gene_names_uniprotkb": "L3mbtl3", "gene_names_refseq": "L3mbtl3", "protein_names_uniprotkb": "L3MBTL histone methyl-lysine binding protein 3", "protein_names_refseq": "L3MBTL3, histone methyl-lysine binding protein; l(3)mbt-like 3; lethal(3)malignant brain tumor-like protein 3 isoform a; lethal(3)malignant brain tumor-like protein 3", "tax_id": 10116, "disease": "brain cancer (Disease Ontology:DOID:1319)", "pathway": " (rno:309550)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0042393 histone binding;GO:0042802 identical protein binding;GO:0140034 methylation-dependent protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription;GO:0006325 chromatin organization;GO:0006355 regulation of DNA-templated transcription;GO:0030851 granulocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZJT9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K9M5-1", "uniprot_id": "A0A0G2K9M5_RAT", "mass": 128579.0, "length": 1122, "protein_name": "TBC1 domain family member 8B", "gene_name": "Tbc1d8b", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Tbc1d8b", "gene_names_refseq": "", "protein_names_uniprotkb": "TBC1 domain family member 8B", "protein_names_refseq": "", "tax_id": 10116, "disease": "nephrotic syndrome type 20 (Disease Ontology:DOID:0070357)", "pathway": " (rno:315912); (R-RNO-432722)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in vesicular recycling, probably as a RAB11B GTPase-activating protein., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0003094 glomerular filtration;GO:0016192 vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K9M5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZDI5-1", "uniprot_id": "D3ZDI5_RAT", "mass": 95344.0, "length": 838, "protein_name": "Rho GTPase-activating protein 12", "gene_name": "Arhgap12", "organism": "Rat", "refseq_name": "rho GTPase-activating protein 12", "refseq_ac": "NP_001100827", "gene_names_uniprotkb": "Arhgap12", "gene_names_refseq": "Arhgap12", "protein_names_uniprotkb": "Rho GTPase-activating protein 12; Rho-type GTPase-activating protein 12", "protein_names_refseq": "rho GTPase-activating protein 12", "tax_id": 10116, "disease": "", "pathway": " (rno:307016); (R-RNO-9013149); (R-RNO-9013424); (R-RNO-9035034)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "22673903;26854232", "class_list": "", "function": "ARHGAP12 negatively controls dendritic spine size via its RhoGAP activity and promotes, by interacting with CIP4, postsynaptic AMPA receptor endocytosis., [RefSeq, PubMed]; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0098978 glutamatergic synapse;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0098794 postsynapse", "go_biological_process": "GO:0006911 phagocytosis, engulfment;GO:0007015 actin filament organization;GO:0007165 signal transduction;GO:0051058 negative regulation of small GTPase mediated signal transduction;GO:0002011 morphogenesis of an epithelial sheet", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZDI5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A0Z1-1", "uniprot_id": "D4A0Z1_RAT", "mass": 30702.0, "length": 270, "protein_name": "Tetraspanin", "gene_name": "Tspan14", "organism": "Rat", "refseq_name": "tetraspanin-14", "refseq_ac": "NP_001162598", "gene_names_uniprotkb": "Tspan14", "gene_names_refseq": "RGD1305714; Tspan14", "protein_names_uniprotkb": "Tetraspanin", "protein_names_refseq": "tetraspanin-14", "tax_id": 10116, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (rno:306324); (R-RNO-6798695)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019899 enzyme binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0097197 tetraspanin-enriched microdomain;GO:0016020 membrane", "go_biological_process": "GO:0072659 protein localization to plasma membrane;GO:0045747 positive regulation of Notch signaling pathway;GO:0051604 protein maturation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A0Z1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K2Z2-1", "uniprot_id": "A0A0G2K2Z2_RAT", "mass": 51852.0, "length": 446, "protein_name": "Inositol polyphosphate 5-phosphatase K", "gene_name": "Inpp5k", "organism": "Rat", "refseq_name": "inositol polyphosphate 5-phosphatase K", "refseq_ac": "NP_001013881", "gene_names_uniprotkb": "Inpp5k", "gene_names_refseq": "Inpp5k; Skip", "protein_names_uniprotkb": "Inositol polyphosphate 5-phosphatase K; 3.1.3.36; 3.1.3.56; 3.1.3.86; Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase; Phosphatidylinositol-4,5-bisphosphate 5-phosphatase; Skeletal muscle and kidney-enriched inositol phosphatase", "protein_names_refseq": "C62; inositol polyphosphate 5-phosphatase K; putative phosphoinositide 5-phosphatase type II; skeletal muscle and kidney enriched inositol phosphatase", "tax_id": 10116, "disease": "muscular dystrophy-dystroglycanopathy type B1 (Disease Ontology:DOID:0050588); congenital muscular dystrophy with cataracts and intellectual disability (Disease Ontology:DOID:0080197)", "pathway": " (rno:287533); (R-RNO-1660499)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22247557", "class_list": "", "function": "Inositol 5-phosphatase which acts on inositol 1,4,5-trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5-trisphosphate. Negatively regulates assembly of the actin cytoskeleton. Controls insulin-dependent glucose uptake among inositol 3,4,5-trisphosphate phosphatases; therefore, is the specific regulator for insulin signaling in skeletal muscle., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Regulation of insulin signaling and glucose transporter 4 (GLUT4) exocytosis by phosphatidylinositol 3,4,5-trisphosphate (PIP3) phosphatase, skeletal muscle, and kidney enriched inositol polyphosphate phosphatase (SKIP)., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.3.86;3.1.3.56;3.1.3.36", "go_molecular_function": "GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity;GO:0004445 inositol-polyphosphate 5-phosphatase activity;GO:0016312 inositol bisphosphate phosphatase activity;GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity;GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0046627 negative regulation of insulin receptor signaling pathway;GO:0032870 cellular response to hormone stimulus;GO:0032868 response to insulin;GO:0051898 negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0046856 phosphatidylinositol dephosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K2Z2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K162-1", "uniprot_id": "A0A0G2K162_RAT", "mass": 116335.0, "length": 1048, "protein_name": "Erythrocyte membrane protein band 4.1-like 2", "gene_name": "Epb41l2", "organism": "Rat", "refseq_name": "band 4.1-like protein 2 isoform X3", "refseq_ac": "XP_038955004", "gene_names_uniprotkb": "Epb41l2", "gene_names_refseq": "Epb4.1l2; Epb41l2; RGD1563977", "protein_names_uniprotkb": "Erythrocyte membrane protein band 4.1-like 2", "protein_names_refseq": "band 4.1-like protein 2 isoform X3", "tax_id": 10116, "disease": "inflammatory bowel disease (Disease Ontology:DOID:0050589)", "pathway": " (rno:309557); (R-RNO-6794361)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "18683930;22673903;29393594", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0005198 structural molecule activity;GO:0030507 spectrin binding;GO:0042731 PH domain binding", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005654 nucleoplasm;GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0030054 cell junction", "go_biological_process": "GO:0030866 cortical actin cytoskeleton organization;GO:0031032 actomyosin structure organization;GO:1904778 positive regulation of protein localization to cell cortex", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A0G2K162-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A2W1-1", "uniprot_id": "D4A2W1_RAT", "mass": 51655.0, "length": 457, "protein_name": "Bis(5'-adenosyl)-triphosphatase ENPP4", "gene_name": "Enpp4", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Enpp4", "gene_names_refseq": "", "protein_names_uniprotkb": "Bis(5'-adenosyl)-triphosphatase ENPP4; 3.6.1.29; AP3A hydrolase; Bis(5'-adenosyl)-triphosphatase enpp4; Ectonucleotide pyrophosphatase/phosphodiesterase family member 4", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-6798695)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.1.29;3.4.16.2;3.6.5.2;3.6.1.-;3.1.4.1;3.6.1.9;2.3.2.27;3.1.3.-;3.1.3.48;3.2.1.20;3.9.1.-;2.7.7.51;3.6.2.1", "go_molecular_function": "GO:0046872 metal ion binding;GO:0047710 bis(5'-adenosyl)-triphosphatase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007596 blood coagulation;GO:0030194 positive regulation of blood coagulation;GO:0046130 purine ribonucleoside catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A2W1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K727-1", "uniprot_id": "A0A0G2K727_RAT", "mass": 59207.0, "length": 519, "protein_name": "UDP-glucuronosyltransferase", "gene_name": "ENSRNOG00000065137", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ENSRNOG00000065137", "gene_names_refseq": "", "protein_names_uniprotkb": "UDP-glucuronosyltransferase; 2.4.1.17", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.1.17", "go_molecular_function": "GO:0015020 glucuronosyltransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K727-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K7F8-1", "uniprot_id": "A0A0G2K7F8_RAT", "mass": 42025.0, "length": 387, "protein_name": "Apolipoprotein L7b like 1", "gene_name": "Apol7bl1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Apol7bl1; Apol7b; RGD1309808", "gene_names_refseq": "", "protein_names_uniprotkb": "Apolipoprotein L7b like 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "substance abuse (Disease Ontology:DOID:302); schizophrenia (Disease Ontology:DOID:5419); kidney disease (Disease Ontology:DOID:557)", "pathway": " (rno:362951); (R-RNO-2168880); (R-RNO-381426); (R-RNO-8957275)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008289 lipid binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0006869 lipid transport;GO:0042157 lipoprotein metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K7F8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K4L7-1", "uniprot_id": "A0A0G2K4L7_RAT", "mass": 95179.0, "length": 851, "protein_name": "DNA polymerase kappa", "gene_name": "Polk", "organism": "Rat", "refseq_name": "DNA polymerase kappa", "refseq_ac": "NP_001420788", "gene_names_uniprotkb": "Polk", "gene_names_refseq": "Dinb1; Polk", "protein_names_uniprotkb": "DNA polymerase kappa; 2.7.7.7; DINB protein", "protein_names_refseq": "DNA polymerase kappa; DNA-directed DNA polymerase kappa; polymerase (DNA directed) kappa; polymerase (DNA) kappa", "tax_id": 10116, "disease": "", "pathway": " (rno:171525); (R-RNO-5655862); (R-RNO-5656169); (R-RNO-5685942); (R-RNO-5693537); (R-RNO-5696397); (R-RNO-5696400); (R-RNO-6782135); (R-RNO-6782210)", "pathway_count": 9, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts. Lacks 3'-5' proofreading exonuclease activity. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.6.2.3;6.5.1.1;2.3.2.32;2.7.7.7;3.1.-.-;5.2.1.8;2.4.2.-;2.7.11.1;2.7.7.102;5.6.2.4;2.7.7.-;2.7.7.6;2.7.7.49;3.6.4.12;5.6.2.1;2.3.2.27;6.3.2.n3;2.7.7.31;3.1.11.-;4.2.99.18;4.2.99.-;2.4.2.30;2.7.11.22;2.7.11.23;2.7.11.24;3.4.19.12;2.3.2.23;2.3.1.48;2.3.1.-;3.6.-.-", "go_molecular_function": "GO:0003887 DNA-directed DNA polymerase activity;GO:0008270 zinc ion binding;GO:0003684 damaged DNA binding;GO:0060090 molecular adaptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0090734 site of DNA damage", "go_biological_process": "GO:0006281 DNA repair;GO:0071897 DNA biosynthetic process;GO:0006297 nucleotide-excision repair, DNA gap filling;GO:0006974 DNA damage response;GO:0034644 cellular response to UV", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K4L7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZLQ6-1", "uniprot_id": "D3ZLQ6_RAT", "mass": 110997.0, "length": 978, "protein_name": "Integrator complex subunit 8", "gene_name": "Ints8", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Ints8; RGD1310592", "gene_names_refseq": "", "protein_names_uniprotkb": "Integrator complex subunit 8", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-6807505)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16641100", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000785 chromatin;GO:0032039 integrator complex;GO:0160232 INTAC complex;GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0034243 regulation of transcription elongation by RNA polymerase II;GO:0071168 protein localization to chromatin;GO:0034472 snRNA 3'-end processing;GO:0160240 RNA polymerase II transcription initiation surveillance;GO:0016180 snRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZLQ6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K2A4-1", "uniprot_id": "A0A0G2K2A4_RAT", "mass": 83636.0, "length": 747, "protein_name": "Transcriptional activator Myb", "gene_name": "Myb", "organism": "Rat", "refseq_name": "transcriptional activator Myb", "refseq_ac": "NP_001414338", "gene_names_uniprotkb": "Myb", "gene_names_refseq": "Myb; RGD1560020", "protein_names_uniprotkb": "Transcriptional activator Myb", "protein_names_refseq": "transcriptional activator Myb; v-myb avian myeloblastosis viral oncogene homolog", "tax_id": 10116, "disease": "adult T-cell leukemia/lymphoma (Disease Ontology:DOID:0050523); B-lymphoblastic leukemia/lymphoma (Disease Ontology:DOID:0080630); essential thrombocythemia (Disease Ontology:DOID:2224); transient cerebral ischemia (Disease Ontology:DOID:224); myelofibrosis (Disease Ontology:DOID:4971)", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "22673903;31210326;33804806", "class_list": "", "function": "Embryonic-Derived Myb(-) Macrophages Enhance Bacterial Clearance and Improve Survival in Rat Sepsis. Publication Status: Online-Only, [RefSeq, PubMed]; Role and mechanism of microRNA-548c-3p/c-Myb in myocardial infarction fibrosis in rats., [RefSeq, PubMed]; Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. 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Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. As part of the intermicrovillar adhesion complex/IMAC plays a role in epithelial brush border differentiation, controlling microvilli organization and length. May link the complex to the actin core bundle of microvilli., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0000146 microfilament motor activity;GO:0003779 actin binding;GO:0003774 cytoskeletal motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005903 brush border;GO:0015629 actin cytoskeleton;GO:0016020 membrane;GO:0005902 microvillus", "go_biological_process": "GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0030154 cell differentiation;GO:0030048 actin filament-based movement;GO:0007605 sensory perception of sound", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K3A7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K3F1-1", "uniprot_id": "A0A0G2K3F1_RAT", "mass": 33798.0, "length": 294, "protein_name": "Similar to human chromosome 3 open reading frame 33", "gene_name": "C2h3orf33", "organism": "Rat", "refseq_name": "protein C3orf33 homolog isoform 2", "refseq_ac": "NP_001386740", "gene_names_uniprotkb": "C2h3orf33; C3orf33l", "gene_names_refseq": "C2h3orf33; C3orf33l; Miso1; RGD1565059", "protein_names_uniprotkb": "Similar to human chromosome 3 open reading frame 33", "protein_names_refseq": "chromosome 3 open reading frame 33 like; protein C3orf33 homolog isoform 2; uncharacterized protein C3orf33 homolog", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane", "go_biological_process": "GO:0070373 negative regulation of ERK1 and ERK2 cascade", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K3F1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K3G2-1", "uniprot_id": "A0A0G2K3G2_RAT", "mass": 36210.0, "length": 323, "protein_name": "Olfactory receptor", "gene_name": "Or10ad1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Or10ad1", "gene_names_refseq": "", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Possible taste receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K3G2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K3K5-1", "uniprot_id": "A0A0G2K3K5_RAT", "mass": 44904.0, "length": 388, "protein_name": "Beta-1,4-galactosyltransferase", "gene_name": "B4galt5", "organism": "Rat", "refseq_name": "beta-1,4-galactosyltransferase 5", "refseq_ac": "NP_001425192", "gene_names_uniprotkb": "B4galt5", "gene_names_refseq": "B4galt5", "protein_names_uniprotkb": "Beta-1,4-galactosyltransferase; 2.4.1.-; Beta-1,4-GalTase", "protein_names_refseq": "UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5; beta-1,4-galactosyltransferase 5", "tax_id": 10116, "disease": "multiple sclerosis (Disease Ontology:DOID:2377)", "pathway": " (rno:362275); (R-RNO-2022854); (R-RNO-913709); (R-RNO-975577); (R-RNO-9840309)", "pathway_count": 5, "publication_count": 3, "publication_id_list": "17917074;18320333;18512149", "class_list": "", "function": "Beta1,4-GalT I and V might play important roles in the regeneration of the injured sciatic nerve. Erratum:[J Mol Histol. 2008 Aug;39(4):469. Xia, Chun [corrected to Xia, Chunlin]], [RefSeq, PubMed]; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids., [UniProtKB, UniProtKB]; These results indicated that the expressions of beta1,4-GalT I, V mRNAs and Galbeta1-4GlcNAc group were involved in the process of denervation and reinnervation., [RefSeq, PubMed]; These results suggest that an autocrine loop involving TNF-alpha, TNFR1 and TNFR2 contributes to the production of beta-1,4-GalT I and V mRNA in response to inflammation., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.1.-;2.4.1.274;2.4.1.275;2.4.1.90;2.4.1.38", "go_molecular_function": "GO:0046872 metal ion binding;GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity;GO:0003945 N-acetyllactosamine synthase activity;GO:0016757 glycosyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0032580 Golgi cisterna membrane;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0022010 central nervous system myelination;GO:0005975 carbohydrate metabolic process;GO:0009101 glycoprotein biosynthetic process;GO:0031647 regulation of protein stability;GO:0040019 positive regulation of embryonic development", "synthesized_glycan_count": 2205, "hit_score": 0.4, "record_id": "A0A0G2K3K5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K3S4-1", "uniprot_id": "A0A0G2K3S4_RAT", "mass": 186606.0, "length": 1653, "protein_name": "ATP binding cassette subfamily A member 9", "gene_name": "Abca9", "organism": "Rat", "refseq_name": "ATP-binding cassette sub-family A member 9", "refseq_ac": "NP_001417081", "gene_names_uniprotkb": "Abca9", "gene_names_refseq": "Abca9", "protein_names_uniprotkb": "ATP binding cassette subfamily A member 9", "protein_names_refseq": "ATP-binding cassette sub-family A member 9-like; ATP-binding cassette sub-family A member 9; ATP-binding cassette transporter sub-family A member 9; ATP-binding cassette, sub-family A (ABC1), member 9; ATP-binding cassette, subfamily A (ABC1), member 9", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-1369062)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005319 lipid transporter activity;GO:0005524 ATP binding;GO:0042626 ATPase-coupled transmembrane transporter activity;GO:0016887 ATP hydrolysis activity;GO:0140359 ABC-type transporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006869 lipid transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K3S4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K4J3-1", "uniprot_id": "A0A0G2K4J3_RAT", "mass": 35557.0, "length": 312, "protein_name": "Olfactory receptor", "gene_name": "Or1e26b", "organism": "Rat", "refseq_name": "olfactory receptor Olr1486", "refseq_ac": "NP_001000720", "gene_names_uniprotkb": "Or1e26b", "gene_names_refseq": "Olr1486; Or1e26b", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1486; olfactory receptor Olr1486; olfactory receptor gene Olr1486", "tax_id": 10116, "disease": "", "pathway": " (rno:404972)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K4J3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K4R2-1", "uniprot_id": "A0A0G2K4R2_RAT", "mass": 54885.0, "length": 479, "protein_name": "glucuronosyltransferase", "gene_name": "Ugt3a1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Ugt3a1; Ugt3a2", "gene_names_refseq": "", "protein_names_uniprotkb": "glucuronosyltransferase; 2.4.1.17", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-156588); (R-RNO-9749641)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.1.17", "go_molecular_function": "GO:0008194 UDP-glycosyltransferase activity;GO:0015020 glucuronosyltransferase activity", "go_cellular_component": "GO:0043541 UDP-N-acetylglucosamine transferase complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K4R2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K4S0-1", "uniprot_id": "A0A0G2K4S0_RAT", "mass": 62511.0, "length": 558, "protein_name": "Schlafen family member 4 like 1", "gene_name": "Slfn4", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Slfn4; Slfn4l1", "gene_names_refseq": "", "protein_names_uniprotkb": "Schlafen family member 4 like 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004540 RNA nuclease activity;GO:0043022 ribosome binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0048286 lung alveolus development;GO:0097190 apoptotic signaling pathway;GO:0009617 response to bacterium;GO:0016075 rRNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K4S0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K5B0-1", "uniprot_id": "TBC24_RAT", "mass": 63410.0, "length": 562, "protein_name": "TBC1 domain family member 24", "gene_name": "Tbc1d24", "organism": "Rat", "refseq_name": "TBC1 domain family member 24 isoform X1", "refseq_ac": "XP_038941277", "gene_names_uniprotkb": "Tbc1d24", "gene_names_refseq": "RGD1306143; Tbc1d24", "protein_names_uniprotkb": "TBC1 domain family member 24", "protein_names_refseq": "TBC1 domain family member 24 isoform X1", "tax_id": 10116, "disease": "nonsyndromic deafness (Disease Ontology:DOID:0050563); myoclonic-atonic epilepsy (Disease Ontology:DOID:0060475); developmental and epileptic encephalopathy 16 (Disease Ontology:DOID:0080449); autosomal recessive nonsyndromic deafness 86 (Disease Ontology:DOID:0110532); autosomal dominant nonsyndromic deafness 65 (Disease Ontology:DOID:0110586); DOORS syndrome (Disease Ontology:DOID:0111627); Rolandic epilepsy-paroxysmal exercise-induced dystonia-writer's cramp syndrome (Disease Ontology:DOID:0111645); neurodegenerative disease (Disease Ontology:DOID:1289)", "pathway": " (rno:287110); (R-RNO-8854214)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "24469796;30858606", "class_list": "", "function": "May act as a GTPase-activating protein for Rab family protein(s) (By similarity). Involved in neuronal projection development, probably through negative modulation of ARF6 function (By similarity). Required for the maintenance of postsynaptic neuron dendritic spines in the adult by suppressing ARF6 activity. Involved in the regulation of synaptic vesicle trafficking (By similarity). Promotes axonal outgrowth and membrane trafficking at the growth cone (PubMed:30858606). Positively regulates radial migration and morphological maturation of pyramidal neurons during cortical development by preventing ARF6 activation (PubMed:24469796). In one study, has been shown to inhibit the activity of the vacuolar-type ATPase (V-ATPase) by inducing disassembly of the V-ATPase complex (By similarity). In another study, has been shown to positively regulate V-ATPase assembly in neurons which promotes acidification of lysosomes and synaptic vesicles (By similarity). This supports neuronal autophagy and also regulates synaptic vesicle reacidification and the maintenance of the synaptic vesicle reserve pool (By similarity). Protects neuronal cells against oxidative stress (By similarity). Involved in the maintainenance of endosomal-mediated vesicle recycling and sustained exocytosis of hair cell ribbon synapses (By similarity). Facilitates formation of tubular recycling endosomes which promotes recycling of clathrin-independent endocytosis cargo proteins back to the plasma membrane (By similarity)., [UniProtKB, UniProtKB, UniProtKB, PubMed, PubMed]; May act as a GTPase-activating protein for Rab family protein(s). Involved in neuronal projections development, probably through a negative modulation of ARF6 function. Involved in the regulation of synaptic vesicle trafficking., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030054 cell junction;GO:0030659 cytoplasmic vesicle membrane;GO:0098793 presynapse", "go_biological_process": "GO:0016358 dendrite development;GO:0031175 neuron projection development;GO:2000463 positive regulation of excitatory postsynaptic potential;GO:0034599 cellular response to oxidative stress;GO:0050775 positive regulation of dendrite morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2K5B0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K5F7-1", "uniprot_id": "A0A0G2K5F7_RAT", "mass": 17520.0, "length": 154, "protein_name": "Zinc finger, HIT-type containing 1", "gene_name": "Znhit1", "organism": "Rat", "refseq_name": "zinc finger HIT domain-containing protein 1 isoform X1", "refseq_ac": "XP_006249153", "gene_names_uniprotkb": "Znhit1", "gene_names_refseq": "Znhit1", "protein_names_uniprotkb": "Zinc finger, HIT-type containing 1", "protein_names_refseq": "zinc finger HIT domain-containing protein 1 isoform X1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0042826 histone deacetylase binding;GO:0042393 histone binding;GO:0031491 nucleosome binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000812 Swr1 complex", "go_biological_process": "GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006338 chromatin remodeling;GO:0070317 negative regulation of G0 to G1 transition;GO:0045815 transcription initiation-coupled chromatin remodeling", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K5F7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K5L8-1", "uniprot_id": "A0A0G2K5L8_RAT", "mass": 35406.0, "length": 316, "protein_name": "Olfactory receptor", "gene_name": "Or8b3c", "organism": "Rat", "refseq_name": "olfactory receptor Olr1231", "refseq_ac": "NP_001000813", "gene_names_uniprotkb": "Or8b3c", "gene_names_refseq": "Olr1231; Or8b3c", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1231; olfactory receptor Olr1231; olfactory receptor gene Olr1231", "tax_id": 10116, "disease": "", "pathway": " (rno:405099)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K5L8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K5M6-1", "uniprot_id": "A0A0G2K5M6_RAT", "mass": 211427.0, "length": 2032, "protein_name": "Proline rich 12", "gene_name": "Prr12", "organism": "Rat", "refseq_name": "proline-rich protein 12", "refseq_ac": "NP_001414781", "gene_names_uniprotkb": "Prr12", "gene_names_refseq": "Prr12; RGD1309896", "protein_names_uniprotkb": "Proline rich 12", "protein_names_refseq": "proline-rich protein 12", "tax_id": 10116, "disease": "", "pathway": " (rno:361569)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 8, "predicted_n_glycosites": 0, "predicted_o_glycosites": 8, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0008104 intracellular protein localization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K5M6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K5Q1-1", "uniprot_id": "A0A0G2K5Q1_RAT", "mass": 34776.0, "length": 311, "protein_name": "Olfactory receptor", "gene_name": "Or9g10", "organism": "Rat", "refseq_name": "olfactory receptor Olr454", "refseq_ac": "NP_001000290", "gene_names_uniprotkb": "Or9g10", "gene_names_refseq": "Olr454; Or9g10", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 454; olfactory receptor Olr454; olfactory receptor gene Olr454", "tax_id": 10116, "disease": "", "pathway": " (rno:295724)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K5Q1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K5S7-1", "uniprot_id": "A0A0G2K5S7_RAT", "mass": 59571.0, "length": 533, "protein_name": "apyrase", "gene_name": "Entpd3", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Entpd3", "gene_names_refseq": "", "protein_names_uniprotkb": "apyrase; 3.6.1.5", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.6.2.3;3.6.4.13;3.6.4.12;2.7.11.1;3.6.1.5;3.6.4.10;3.6.4.-;2.3.2.27;5.6.2.4;3.6.5.-;5.6.2.-;3.1.-.-;2.7.7.7;2.7.7.49;3.1.13.1;4.2.99.18;7.6.2.2;7.6.2.3;7.6.2.-;5.6.1.6;7.2.2.-;3.6.1.15;3.6.4.6;3.1.3.1;3.9.1.1;6.1.1.12;3.6.1.-;2.7.4.3;3.1.4.-;3.6.1.6;3.4.24.-;3.6.-.-;3.4.21.53;5.6.2.5", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0043262 ADP phosphatase activity;GO:0017110 nucleoside diphosphate phosphatase activity;GO:0017111 ribonucleoside triphosphate phosphatase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0035457 cellular response to interferon-alpha;GO:0071222 cellular response to lipopolysaccharide;GO:0010996 response to auditory stimulus;GO:0071356 cellular response to tumor necrosis factor;GO:0009143 nucleoside triphosphate catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K5S7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K5V0-1", "uniprot_id": "A0A0G2K5V0_RAT", "mass": 21502.0, "length": 185, "protein_name": "CKLF-like MARVEL transmembrane domain containing 2B", "gene_name": "Cmtm2b", "organism": "Rat", "refseq_name": "CKLF-like MARVEL transmembrane domain-containing protein 2B-like", "refseq_ac": "NP_001406615", "gene_names_uniprotkb": "Cmtm2b; 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Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. 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ORC is required to assemble the pre-replication complex necessary to initiate DNA replication., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0000785 chromatin;GO:0005664 nuclear origin of replication recognition complex;GO:0000808 origin recognition complex;GO:0005634 nucleus", "go_biological_process": "GO:0006275 regulation of DNA replication;GO:0006270 DNA replication initiation;GO:0006260 DNA replication", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K6D6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K6E6-1", "uniprot_id": "A0A0G2K6E6_RAT", "mass": 93982.0, "length": 835, "protein_name": "Rho GTPase-activating protein 20-like", "gene_name": "LOC120093152", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LOC120093152", "gene_names_refseq": "", "protein_names_uniprotkb": "Rho GTPase-activating protein 20-like", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "", "go_biological_process": "GO:0007165 signal transduction;GO:0035023 regulation of Rho protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K6E6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K6I0-1", "uniprot_id": "A0A0G2K6I0_RAT", "mass": 14400.0, "length": 127, "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "Rps15a-ps9", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Rps15a-ps9", "gene_names_refseq": "", "protein_names_uniprotkb": "Small ribosomal subunit protein uS8; 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RGD1311640", "protein_names_uniprotkb": "Centrosomal protein 290", "protein_names_refseq": "centrosomal protein 290kDa; centrosomal protein of 290 kDa isoform 2; centrosomal protein of 290 kDa", "tax_id": 10116, "disease": "visceral heterotaxy (Disease Ontology:DOID:0050545); Senior-Loken syndrome (Disease Ontology:DOID:0050576); ciliopathy (Disease Ontology:DOID:0060340); Meckel syndrome 4 (Disease Ontology:DOID:0070118); Bardet-Biedl syndrome 14 (Disease Ontology:DOID:0110136); Leber congenital amaurosis 10 (Disease Ontology:DOID:0110291); Joubert syndrome 5 (Disease Ontology:DOID:0111000); Leber congenital amaurosis (Disease Ontology:DOID:14791); cystic kidney disease (Disease Ontology:DOID:2975); kidney disease (Disease Ontology:DOID:557); retinal degeneration (Disease Ontology:DOID:8466)", "pathway": " (rno:314787); (R-RNO-2565942); (R-RNO-380259); (R-RNO-380270); (R-RNO-380284); (R-RNO-380320); (R-RNO-5620912); (R-RNO-6798695); (R-RNO-8854518)", "pathway_count": 9, "publication_count": 1, "publication_id_list": "38843836", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 11, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005829 cytosol;GO:0005814 centriole", "go_biological_process": "GO:0007507 heart development;GO:0015031 protein transport;GO:0090316 positive regulation of intracellular protein transport;GO:0001822 kidney development;GO:0097711 ciliary basal body-plasma membrane docking", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2K715-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K7B6-1", "uniprot_id": "A0A0G2K7B6_RAT", "mass": 242462.0, "length": 2134, "protein_name": "Dysferlin", "gene_name": "Dysf", "organism": "Rat", "refseq_name": "dysferlin isoform X4", "refseq_ac": "XP_006236820", "gene_names_uniprotkb": "Dysf", "gene_names_refseq": "Dysf", "protein_names_uniprotkb": "Dysferlin; Dystrophy-associated fer-1-like protein; Fer-1-like protein 1", "protein_names_refseq": "dysferlin isoform X4", "tax_id": 10116, "disease": "Miyoshi muscular dystrophy 1 (Disease Ontology:DOID:0070199); autosomal recessive limb-girdle muscular dystrophy type 2B (Disease Ontology:DOID:0110276); distal myopathy with anterior tibial onset (Disease Ontology:DOID:0111187); distal myopathy (Disease Ontology:DOID:11720); limb-girdle muscular dystrophy (Disease Ontology:DOID:11724); muscular dystrophy (Disease Ontology:DOID:9884)", "pathway": " (rno:312492)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "22673903;29393594", "class_list": "", "function": "Key calcium ion sensor involved in the Ca(2+)-triggered synaptic vesicle-plasma membrane fusion. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0005544 calcium-dependent phospholipid binding;GO:0046872 metal ion binding;GO:0008289 lipid binding;GO:0005543 phospholipid binding", "go_cellular_component": "GO:0005769 early endosome;GO:0015630 microtubule cytoskeleton;GO:0031902 late endosome membrane;GO:0030139 endocytic vesicle;GO:0030315 T-tubule", "go_biological_process": "GO:0001778 plasma membrane repair;GO:0050765 negative regulation of phagocytosis;GO:0033292 T-tubule organization;GO:0006071 glycerol metabolic process;GO:0002281 macrophage activation involved in immune response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2K7B6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K7E7-1", "uniprot_id": "A0A0G2K7E7_RAT", "mass": 7493.0, "length": 68, "protein_name": "Protein transport protein Sec61 subunit gamma", "gene_name": "Sec61gl2", "organism": "Rat", "refseq_name": "protein transport protein Sec61 subunit gamma-like", "refseq_ac": "XP_038952383", "gene_names_uniprotkb": "Sec61gl2; AABR07028668.1; LOC108348617", "gene_names_refseq": "Sec61gl2", "protein_names_uniprotkb": "Protein transport protein Sec61 subunit gamma", "protein_names_refseq": "protein transport protein Sec61 subunit gamma-like", "tax_id": 10116, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (rno:108348617)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER). Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides. The SEC61 channel is also involved in ER membrane insertion of transmembrane proteins: it mediates membrane insertion of the first few transmembrane segments of proteins, while insertion of subsequent transmembrane regions of multi-pass membrane proteins is mediated by the multi-pass translocon (MPT) complex. The SEC61 channel cooperates with the translocating protein TRAM1 to import nascent proteins into the ER., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008320 protein transmembrane transporter activity", "go_cellular_component": "GO:0071261 Ssh1 translocon complex", "go_biological_process": "GO:0031204 post-translational protein targeting to membrane, translocation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K7E7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K7F0-1", "uniprot_id": "A0A0G2K7F0_RAT", "mass": 225106.0, "length": 2017, "protein_name": "RNA helicase", "gene_name": "Fancm", "organism": "Rat", "refseq_name": "Fanconi anemia group M protein", "refseq_ac": "NP_001414592", "gene_names_uniprotkb": "Fancm", "gene_names_refseq": "Fancm; RGD1307897", "protein_names_uniprotkb": "RNA helicase; 3.6.4.13; ATP-dependent RNA helicase FANCM", "protein_names_refseq": "Fanconi anemia group M protein; Fanconi anemia, complementation group M", "tax_id": 10116, "disease": "tongue squamous cell carcinoma (Disease Ontology:DOID:0050865); primary ovarian insufficiency 15 (Disease Ontology:DOID:0080872); spermatogenic failure 28 (Disease Ontology:DOID:0111916); Fanconi anemia (Disease Ontology:DOID:13636)", "pathway": " (R-RNO-6783310); (R-RNO-9833482)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork-structured DNA (fsDNA) and Holliday junction substrates. Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork. This activity is strongly stimulated in the presence of CENPS and CENPX. In complex with FAAP24, efficiently binds to single-strand DNA (ssDNA), splayed-arm DNA, and 3'-flap substrates. In vitro, on its own, strongly binds ssDNA oligomers and weakly fsDNA, but does not bind to dsDNA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, 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RGD1564677", "protein_names_uniprotkb": "One cut homeobox 2", "protein_names_refseq": "one cut domain family member 2 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:307376)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:1990837 sequence-specific double-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0001889 liver development;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030335 positive regulation of cell migration;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2KA21-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2KAA5-1", "uniprot_id": "A0A0G2KAA5_RAT", "mass": 46553.0, "length": 417, "protein_name": "Zinc finger protein 772", "gene_name": "Zfp772", "organism": "Rat", "refseq_name": "zinc finger protein 419 isoform 1", "refseq_ac": "NP_001386303", "gene_names_uniprotkb": "Zfp772", "gene_names_refseq": "RGD1308782; Zfp772; Zfp978", "protein_names_uniprotkb": "Zinc finger protein 772", "protein_names_refseq": "zinc finger protein 419 isoform 1; zinc finger protein 419; zinc finger protein 978", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2KAA5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2KAE2-1", "uniprot_id": "A0A0G2KAE2_RAT", "mass": 39622.0, "length": 348, "protein_name": "Tumor suppressor candidate 3", "gene_name": "Tusc3", "organism": "Rat", "refseq_name": "tumor suppressor candidate 3 isoform X1", "refseq_ac": "XP_038950316", "gene_names_uniprotkb": "Tusc3", "gene_names_refseq": "Tusc3", "protein_names_uniprotkb": "Tumor suppressor candidate 3", "protein_names_refseq": "tumor suppressor candidate 3 isoform X1", "tax_id": 10116, "disease": "autosomal recessive intellectual developmental disorder 7 (Disease Ontology:DOID:0081183); prostate cancer (Disease Ontology:DOID:10283); bacterial infectious disease (Disease Ontology:DOID:104)", "pathway": " (rno:290783); (R-RNO-5223345); (R-RNO-9931295)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "38843836", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0062062 oligosaccharyltransferase complex binding;GO:0015095 magnesium ion transmembrane transporter activity", "go_cellular_component": "GO:0008250 oligosaccharyltransferase complex;GO:0005739 mitochondrion;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0015693 magnesium ion transport;GO:0050890 cognition;GO:0006487 protein N-linked glycosylation;GO:1903830 magnesium ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A0G2KAE2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2KAH6-1", "uniprot_id": "A0A0G2KAH6_RAT", "mass": 65326.0, "length": 592, "protein_name": "SRSF protein kinase 3", "gene_name": "Srpk3", "organism": "Rat", "refseq_name": "SRSF protein kinase 3 isoform X2", "refseq_ac": "XP_006229621", "gene_names_uniprotkb": "Srpk3", "gene_names_refseq": "Mssk1; Srpk3; Stk23", "protein_names_uniprotkb": "SRSF protein kinase 3; 2.7.11.1; Muscle-specific serine kinase 1; Serine/arginine-rich protein-specific kinase 3; Serine/threonine-protein kinase 23", "protein_names_refseq": "SRSF protein kinase 3 isoform X2", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.12.1;2.7.1.153;2.7.1.137;2.7.11.24;2.7.11.25;2.7.11.22;2.7.11.23;2.7.4.6;2.7.1.154;2.7.11.38;2.7.11.17;2.7.11.21;2.7.12.2;2.7.1.40;2.7.11.12;2.7.11.26;2.7.11.34;2.7.10.2;2.7.1.150;2.7.11.13;4.1.1.32;2.7.11.19;2.7.2.3;2.7.11.11;2.7.11.31;3.1.3.16;2.7.11.4;2.3.1.48;3.1.11.-;2.7.13.3;2.7.4.18;3.1.24.-;3.4.19.12;2.7.11.39;2.4.99.18;2.7.11.10", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006468 protein phosphorylation;GO:0035556 intracellular signal transduction;GO:0000245 spliceosomal complex assembly;GO:0060537 muscle tissue development;GO:0007519 skeletal muscle tissue development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2KAH6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2KAQ9-1", "uniprot_id": "A0A0G2KAQ9_RAT", "mass": 87652.0, "length": 773, "protein_name": "Telomere repeats-binding bouquet formation protein 1", "gene_name": "Terb1", "organism": "Rat", "refseq_name": "telomere repeat binding bouquet formation protein 1 isoform 1", "refseq_ac": "NP_001418236", "gene_names_uniprotkb": "Terb1; Ccdc79", "gene_names_refseq": "Ccdc79; RGD1310400; Terb1", "protein_names_uniprotkb": "Telomere repeats-binding bouquet formation protein 1; Coiled-coil domain-containing protein 79", "protein_names_refseq": "coiled-coil domain containing 79; telomere repeat binding bouquet formation protein 1 isoform 1; telomere repeats-binding bouquet formation protein 1", "tax_id": 10116, "disease": "spermatogenic failure 60 (Disease Ontology:DOID:0112355)", "pathway": " (rno:307615)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and synapsis. Component of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap exchange by mediating attachment of telomeric DNA to the inner nuclear membrane and replacement of the protective cap of telomeric chromosomes: in early meiosis, the MAJIN-TERB1-TERB2 complex associates with telomeric DNA and the shelterin/telosome complex. During prophase, the complex matures and promotes release of the shelterin/telosome complex from telomeric DNA. In the MAJIN-TERB1-TERB2 complex, TERB1 probably mediates association with the shelterin/telosome complex via interaction with TERF1, promoting priming telomeric DNA attachment'. Promotes telomere association with the nuclear envelope and deposition of the SUN-KASH/LINC complex. Also recruits cohesin to telomeres to develop structural rigidity., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0070187 shelterin complex;GO:0005637 nuclear inner membrane;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0070197 meiotic attachment of telomere to nuclear envelope;GO:0007129 homologous chromosome pairing at meiosis;GO:1990918 double-strand break repair involved in meiotic recombination;GO:0045141 meiotic telomere clustering", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2KAQ9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2KAX2-1", "uniprot_id": "A0A0G2KAX2_RAT", "mass": 62821.0, "length": 580, "protein_name": "Trafficking protein particle complex subunit 14", "gene_name": "Trappc14", "organism": "Rat", "refseq_name": "trafficking protein particle complex subunit 14", "refseq_ac": "NP_001020140", "gene_names_uniprotkb": "Trappc14; RGD1305455", "gene_names_refseq": "Map11; RGD1305455; Trappc14", "protein_names_uniprotkb": "Trafficking protein particle complex subunit 14", "protein_names_refseq": "microtubule associated protein 11; trafficking protein particle complex 14; trafficking protein particle complex subunit 14; uncharacterized protein C7orf43 homolog", "tax_id": 10116, "disease": "primary autosomal recessive microcephaly 25 (Disease Ontology:DOID:0051036)", "pathway": " (rno:288545)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0043014 alpha-tubulin binding", "go_cellular_component": "GO:0030496 midbody;GO:0034451 centriolar satellite;GO:0072686 mitotic spindle;GO:1990071 TRAPPII protein complex", "go_biological_process": "GO:0042127 regulation of cell population proliferation;GO:0060271 cilium assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2KAX2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2KB39-1", "uniprot_id": "A0A0G2KB39_RAT", "mass": 25799.0, "length": 225, "protein_name": "Myb/SANT DNA binding domain containing 5 like 1", "gene_name": "Msantd5l1", "organism": "Rat", "refseq_name": "putative uncharacterized protein MSANTD5", "refseq_ac": "XP_038943114", "gene_names_uniprotkb": "Msantd5l1; LOC120095094", "gene_names_refseq": "Msantd5l1", "protein_names_uniprotkb": "Myb/SANT DNA binding domain containing 5 like 1", "protein_names_refseq": "putative uncharacterized protein MSANTD5", "tax_id": 10116, "disease": "", "pathway": " (rno:120095094)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2KB39-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2QC08-1", "uniprot_id": "A0A0G2QC08_RAT", "mass": 31370.0, "length": 296, "protein_name": "C1q and TNF related 7", "gene_name": "C1qtnf7", "organism": "Rat", "refseq_name": "complement C1q tumor necrosis factor-related protein 7 isoform 2 precursor", "refseq_ac": "NP_001423759", "gene_names_uniprotkb": "C1qtnf7", "gene_names_refseq": "Adig; 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Acts as a nucleolar anchoring protein for DDX47. May be involved in regulation of gene expression at the post-transcriptional level or in ribosome biogenesis in cancer cells., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005730 nucleolus", "go_biological_process": "GO:1902570 protein localization to nucleolus;GO:1990830 cellular response to leukemia inhibitory factor;GO:0006364 rRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A1W2Q629-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A1W2Q6A1-1", "uniprot_id": "A0A1W2Q6A1_RAT", "mass": 43903.0, "length": 385, "protein_name": "Asporin", "gene_name": "Aspn", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Aspn", "gene_names_refseq": "", "protein_names_uniprotkb": "Asporin", "protein_names_refseq": "", "tax_id": 10116, "disease": "ankylosing spondylitis (Disease Ontology:DOID:7147); osteoarthritis (Disease Ontology:DOID:8398); degenerative disc disease (Disease Ontology:DOID:90)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0031012 extracellular matrix;GO:0042995 cell projection", "go_biological_process": "GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030282 bone mineralization;GO:0070171 negative regulation of tooth mineralization;GO:1902617 response to fluoride", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1W2Q6A1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3Z7Z1-1", "uniprot_id": "D3Z7Z1_RAT", "mass": 34818.0, "length": 311, "protein_name": "Olfactory receptor", "gene_name": "Or4c107", "organism": "Rat", "refseq_name": "olfactory receptor Olr664", "refseq_ac": "NP_001000347", "gene_names_uniprotkb": "Or4c107", "gene_names_refseq": "Olr664; Or4c107", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 664; olfactory receptor Olr664; olfactory receptor gene Olr664", "tax_id": 10116, "disease": "", "pathway": " (rno:295870)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. 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[provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 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Motor protein that moves towards the plus-end of actin filaments. Required for mitochondrial inheritance during mitosis. 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As a CIA complex component and in collaboration with CIAO1 and MMS19, binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. 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Or4c58; ratchr3-74174818-74173907_ORF", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 721; olfactory receptor Olr721; olfactory receptor gene Olr721", "tax_id": 10116, "disease": "", "pathway": " (rno:295914)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3Z928-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3Z954-1", "uniprot_id": "D3Z954_RAT", "mass": 61581.0, "length": 539, "protein_name": "PAT1 homolog 2", "gene_name": "Patl2", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Patl2", "gene_names_refseq": "", "protein_names_uniprotkb": "PAT1 homolog 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "ovarian disease (Disease Ontology:DOID:1100)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000932 P-body", "go_biological_process": "GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0033962 P-body assembly;GO:0010607 negative regulation of cytoplasmic mRNA processing body assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3Z954-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3Z967-1", "uniprot_id": "D3Z967_RAT", "mass": 31564.0, "length": 283, "protein_name": "Tetraspanin", "gene_name": "Tspan33", "organism": "Rat", "refseq_name": "tetraspanin-33", "refseq_ac": "NP_001102697", "gene_names_uniprotkb": "Tspan33", "gene_names_refseq": "RGD1560915; Tspan33", "protein_names_uniprotkb": "Tetraspanin", "protein_names_refseq": "tetraspanin-33", "tax_id": 10116, "disease": "", "pathway": " (rno:500065)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "Part of TspanC8 subgroup, composed of 6 members that interact with the transmembrane metalloprotease ADAM10. This interaction is required for ADAM10 exit from the endoplasmic reticulum and for enzymatic maturation and trafficking to the cell surface as well as substrate specificity. Different TspanC8/ADAM10 complexes have distinct substrates. Plays an important role in normal erythropoiesis. It has a role in the differentiation of erythroid progenitors. Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity. Mediates docking of ADAM10 to zonula adherens by interacting with ADAM10 and, in a PDZD11-dependent manner, with the zonula adherens protein PLEKHA7., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019899 enzyme binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005912 adherens junction;GO:0009986 cell surface;GO:0097197 tetraspanin-enriched microdomain", "go_biological_process": "GO:0072659 protein localization to plasma membrane;GO:0046931 pore complex assembly;GO:0051604 protein maturation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3Z967-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3Z9A5-1", "uniprot_id": "D3Z9A5_RAT", "mass": 79273.0, "length": 724, "protein_name": "BTB/POZ domain-containing protein 18", "gene_name": "Btbd18", "organism": "Rat", "refseq_name": "BTB domain containing 18", "refseq_ac": "NP_001417674", "gene_names_uniprotkb": "Btbd18", "gene_names_refseq": "Btbd18", "protein_names_uniprotkb": "BTB/POZ domain-containing protein 18", "protein_names_refseq": "BTB (POZ) domain containing 18; BTB domain containing 18; BTB/POZ domain-containing protein 18; zinc finger and BTB domain containing 45-like", "tax_id": 10116, "disease": "", "pathway": " (rno:100363270)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Specifically required during spermatogenesis to promote expression of piRNA precursors. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons, which is essential for the germline integrity. Acts by facilitating transcription elongation at piRNA loci during pachytene., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0007141 male meiosis I;GO:0032968 positive regulation of transcription elongation by RNA polymerase II;GO:0010526 transposable element silencing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3Z9A5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3Z9E5-1", "uniprot_id": "D3Z9E5_RAT", "mass": 66422.0, "length": 611, "protein_name": "Sodium-coupled monocarboxylate transporter 1", "gene_name": "Slc5a8", "organism": "Rat", "refseq_name": "sodium-coupled monocarboxylate transporter 1", "refseq_ac": "NP_001178916", "gene_names_uniprotkb": "Slc5a8", "gene_names_refseq": "RGD1564146; Slc5a8", "protein_names_uniprotkb": "Sodium-coupled monocarboxylate transporter 1; Electrogenic sodium monocarboxylate cotransporter; Solute carrier family 5 member 8", "protein_names_refseq": "sodium-coupled monocarboxylate transporter 1; solute carrier family 5 (iodide transporter), member 8; solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8", "tax_id": 10116, "disease": "", "pathway": " (rno:500820); (R-RNO-196807); (R-RNO-428643); (R-RNO-9958790)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "20211600;20671196;22123132", "class_list": "", "function": "A high affinity type of SMCT1-like transporter, additionally in operation in the ileum, is involved in the transport of nicotinate., [RefSeq, PubMed]; Efficacy of LP or their secreted soluble factors to stimulate SMCT1 expression and function and to counteract the inhibitory effects of TNF-alpha on butyrate absorption could have potential therapeutic value., [RefSeq, PubMed]; Sodium-coupled electrogenic transport of pyroglutamate (5-oxoproline) via SLC5A8, a monocarboxylate transporter., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "7.6.2.2;7.6.2.3;7.6.2.-;5.6.1.6;1.11.1.-;1.8.-.-;1.8.5.1", "go_molecular_function": "GO:0090416 nicotinate transmembrane transporter activity;GO:0005343 organic acid:sodium symporter activity;GO:0015636 short-chain fatty acid transmembrane transporter activity;GO:0015129 lactate transmembrane transporter activity;GO:0015552 propionate transmembrane transporter activity", "go_cellular_component": "GO:0016324 apical plasma membrane;GO:0000811 GINS complex", "go_biological_process": "GO:0006821 chloride transport;GO:0015705 iodide transport;GO:2001142 nicotinate transport;GO:0015718 monocarboxylic acid transport;GO:0015913 short-chain fatty acid transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "D3Z9E5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3Z9F7-1", "uniprot_id": "D3Z9F7_RAT", "mass": 155261.0, "length": 1406, "protein_name": "Complement component receptor 1-like protein", "gene_name": "Cr2", "organism": "Rat", "refseq_name": "complement receptor type 2 isoform X1", "refseq_ac": "XP_008768069", "gene_names_uniprotkb": "Cr2", "gene_names_refseq": "Cd21; Cr2", "protein_names_uniprotkb": "Complement component receptor 1-like protein; Complement regulatory protein Crry", "protein_names_refseq": "complement receptor type 2 isoform X1", "tax_id": 10116, "disease": "common variable immunodeficiency 7 (Disease Ontology:DOID:0081150); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); systemic lupus erythematosus (Disease Ontology:DOID:9074); nasopharynx carcinoma (Disease Ontology:DOID:9261)", "pathway": " (R-RNO-977606)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0034987 immunoglobulin receptor binding;GO:0004875 complement receptor activity;GO:0003677 DNA binding;GO:0004888 transmembrane signaling receptor activity;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0043235 receptor complex;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0006954 inflammatory response;GO:0042113 B cell activation;GO:0060337 type I interferon-mediated signaling pathway;GO:0071222 cellular response to lipopolysaccharide;GO:0007565 female pregnancy", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3Z9F7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3Z9G1-1", "uniprot_id": "D3Z9G1_RAT", "mass": 52122.0, "length": 466, "protein_name": "F-box and WD-40 domain protein 17", "gene_name": "Fbxw17", "organism": "Rat", "refseq_name": "Fbxw17 protein", "refseq_ac": "NP_001075878", "gene_names_uniprotkb": "Fbxw17", "gene_names_refseq": "Fbxw17; RGD1566133", "protein_names_uniprotkb": "F-box and WD-40 domain protein 17", "protein_names_refseq": "Fbxw17 protein", "tax_id": 10116, "disease": "", "pathway": " (rno:361219); (R-RNO-8951664); (R-RNO-983168)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3Z9G1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3Z9K4-1", "uniprot_id": "D3Z9K4_RAT", "mass": 54007.0, "length": 494, "protein_name": "Pleckstrin homology domain containing O2", "gene_name": "Plekho2", "organism": "Rat", "refseq_name": "pleckstrin homology domain-containing family O member 2", "refseq_ac": "NP_001417474", "gene_names_uniprotkb": "Plekho2", "gene_names_refseq": "Plekho2; Plekhq1; RGD1305718", "protein_names_uniprotkb": "Pleckstrin homology domain containing O2", "protein_names_refseq": "HQ0024c protein; pleckstrin homology domain containing, family O member 2; pleckstrin homology domain containing, family Q member 1; pleckstrin homology domain-containing family O member 2", "tax_id": 10116, "disease": "", "pathway": " (rno:315764)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0071888 macrophage apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3Z9K4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3Z9K5-1", "uniprot_id": "D3Z9K5_RAT", "mass": 63271.0, "length": 571, "protein_name": "WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2", "gene_name": "Wfikkn2", "organism": "Rat", "refseq_name": "WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 precursor", "refseq_ac": "NP_001385521", "gene_names_uniprotkb": "Wfikkn2", "gene_names_refseq": "RGD1305361; Wfikkn2", "protein_names_uniprotkb": "WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2; Growth and differentiation factor-associated serum protein 1", "protein_names_refseq": "WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 precursor; WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2", "tax_id": 10116, "disease": "", "pathway": " (rno:287631)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity. Inhibits the biological activity of mature myostatin, but not activin., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity;GO:0048019 receptor antagonist activity;GO:0050431 transforming growth factor beta binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space", "go_biological_process": "GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0001501 skeletal system development;GO:0060021 roof of mouth development;GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway;GO:0055001 muscle cell development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3Z9K5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3Z9M1-1", "uniprot_id": "D3Z9M1_RAT", "mass": 62593.0, "length": 553, "protein_name": "U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase", "gene_name": "Mettl16", "organism": "Rat", "refseq_name": "RNA N6-adenosine-methyltransferase METTL16", "refseq_ac": "NP_001388962", "gene_names_uniprotkb": "Mettl16", "gene_names_refseq": "Mett10d; Mettl16", "protein_names_uniprotkb": "U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; 2.1.1.-", "protein_names_refseq": "RNA N6-adenosine-methyltransferase METTL16; methyltransferase 10 domain containing; methyltransferase 16, N6-methyladenosine; methyltransferase like 16", "tax_id": 10116, "disease": "", "pathway": " (rno:360568)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "37673880", "class_list": "", "function": "METTL16 controls Kaposi's sarcoma-associated herpesvirus replication by regulating S-adenosylmethionine cycle. Publication Status: Online-Only, [RefSeq, PubMed]; RNA N6-methyltransferase that methylates adenosine residues at the N(6) position of a subset of RNAs and is involved in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6-methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001734 mRNA m(6)A methyltransferase activity;GO:0003723 RNA binding;GO:0035613 RNA stem-loop binding;GO:0030629 U6 snRNA 3'-end binding;GO:0120048 U6 snRNA (adenine-(43)-N(6))-methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0006397 mRNA processing;GO:0010608 post-transcriptional regulation of gene expression;GO:0006402 mRNA catabolic process;GO:0006556 S-adenosylmethionine biosynthetic process;GO:0061157 mRNA destabilization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3Z9M1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3Z9V2-1", "uniprot_id": "D3Z9V2_RAT", "mass": 36798.0, "length": 325, "protein_name": "Olfactory receptor", "gene_name": "Or6c63", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Or6c63", "gene_names_refseq": "", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3Z9V2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3Z9Z2-1", "uniprot_id": "D3Z9Z2_RAT", "mass": 25197.0, "length": 231, "protein_name": "Octanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase LIPT2, mitochondrial", "gene_name": "Lipt2", "organism": "Rat", "refseq_name": "octanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase LIPT2, mitochondrial", "refseq_ac": "NP_001102387", "gene_names_uniprotkb": "Lipt2", "gene_names_refseq": "Lipt2; RGD1305211", "protein_names_uniprotkb": "Octanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase LIPT2, mitochondrial; 2.3.1.181", "protein_names_refseq": "lipoyl(octanoyl) transferase 2 (putative); octanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase LIPT2, mitochondrial; putative lipoyltransferase 2, mitochondrial", "tax_id": 10116, "disease": "dystonia (Disease Ontology:DOID:543); glycine encephalopathy (Disease Ontology:DOID:9268)", "pathway": " (rno:365314); (R-RNO-9857492)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.1.181", "go_molecular_function": "GO:0033819 lipoyl(octanoyl) transferase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0009249 protein lipoylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3Z9Z2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZA55-1", "uniprot_id": "D3ZA55_RAT", "mass": 71109.0, "length": 636, "protein_name": "Ecdysoneless cell cycle regulator", "gene_name": "Ecd", "organism": "Rat", "refseq_name": "protein ecdysoneless homolog", "refseq_ac": "NP_001414124", "gene_names_uniprotkb": "Ecd; RGD1565023", "gene_names_refseq": "Ecd; RGD1565023", "protein_names_uniprotkb": "Ecdysoneless cell cycle regulator", "protein_names_refseq": "ecdysoneless homolog; protein ecdysoneless homolog", "tax_id": 10116, "disease": "", "pathway": " (rno:688968)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0035035 histone acetyltransferase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0008283 cell population proliferation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:2000045 regulation of G1/S transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZA55-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZA80-1", "uniprot_id": "D3ZA80_RAT", "mass": 27098.0, "length": 243, "protein_name": "Juxtaposed with another zinc finger protein 1", "gene_name": "Jazf1", "organism": "Rat", "refseq_name": "juxtaposed with another zinc finger protein 1", "refseq_ac": "NP_001387781", "gene_names_uniprotkb": "Jazf1", "gene_names_refseq": "Jazf1", "protein_names_uniprotkb": "Juxtaposed with another zinc finger protein 1", "protein_names_refseq": "juxtaposed with another zinc finger protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:685879)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32275331", "class_list": "", "function": "Acts as a transcriptional corepressor of orphan nuclear receptor NR2C2. Inhibits expression of the gluconeogenesis enzyme PCK2 through inhibition of NR2C2 activity. Also involved in transcriptional activation of NAMPT by promoting expression of PPARA and PPARD. Plays a role in lipid metabolism by suppressing lipogenesis, increasing lipolysis and decreasing lipid accumulation in adipose tissue. Plays a role in glucose homeostasis by improving glucose metabolism and insulin sensitivity., [UniProtKB, UniProtKB]; Effect of central JAZF1 on glucose production is regulated by the PI3K-Akt-AMPK pathway., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003714 transcription corepressor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0017053 transcription repressor complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZA80-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZAF1-1", "uniprot_id": "D3ZAF1_RAT", "mass": 35853.0, "length": 319, "protein_name": "Olfactory receptor", "gene_name": "Or51f1f", "organism": "Rat", "refseq_name": "olfactory receptor Olr75", "refseq_ac": "NP_001001281", "gene_names_uniprotkb": "Or51f1f", "gene_names_refseq": "Olr75; Or51f1f", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 75; olfactory receptor Olr75; olfactory receptor gene Olr75", "tax_id": 10116, "disease": "", "pathway": " (rno:365327)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0071396 cellular response to lipid", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZAF1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZAH0-1", "uniprot_id": "D3ZAH0_RAT", "mass": 88483.0, "length": 822, "protein_name": "Taste receptor cell protein 1-like", "gene_name": "LOC134480056", "organism": "Rat", "refseq_name": "LOW QUALITY PROTEIN: taste receptor cell protein 1-like", "refseq_ac": "XP_063122405", "gene_names_uniprotkb": "LOC134480056", "gene_names_refseq": "LOC134480056", "protein_names_uniprotkb": "Taste receptor cell protein 1-like", "protein_names_refseq": "LOW QUALITY PROTEIN: taste receptor cell protein 1-like", "tax_id": 10116, "disease": "", "pathway": " (rno:134480056)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZAH0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZAL7-1", "uniprot_id": "D3ZAL7_RAT", "mass": 80090.0, "length": 724, "protein_name": "GRB2-associated binding protein 1", "gene_name": "Gab1", "organism": "Rat", "refseq_name": "GRB2-associated-binding protein 1 isoform X1", "refseq_ac": "XP_038953749", "gene_names_uniprotkb": "Gab1", "gene_names_refseq": "Gab1", "protein_names_uniprotkb": "GRB2-associated binding protein 1", "protein_names_refseq": "GRB2-associated-binding protein 1 isoform X1", "tax_id": 10116, "disease": "autosomal recessive nonsyndromic deafness 26 (Disease Ontology:DOID:0110484)", "pathway": " (R-RNO-109704); 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. Determines the cell type specificity of the lambda interferon action. Shows a more restricted pattern of expression in the epithelial tissues thereby limiting responses to lambda interferons primarily to epithelial cells of the respiratory, gastrointestinal, and reproductive tracts. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. 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(R-RNO-5626467); (R-RNO-8980692); (R-RNO-9013026); (R-RNO-9013106); (R-RNO-9013149); (R-RNO-9013406)", "pathway_count": 7, "publication_count": 3, "publication_id_list": "17244649;29393594;29522098", "class_list": "", "function": "Iqgap3, a novel effector of Rac1 and Cdc42, regulates neurite outgrowth., [RefSeq, PubMed]; Naturally occurring cytokinesis failure in primary cardiomyocytes is due to an aberrant mitotic microtubule apparatus and mislocalization of RhoA and IQGAP3 resulting in inefficient anchorage of the actomyosin ring to the plasma cell membrane., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005516 calmodulin binding;GO:0051015 actin filament binding;GO:0031267 small GTPase binding;GO:0070856 myosin VI light chain binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005911 cell-cell junction;GO:0005938 cell cortex;GO:0016328 lateral plasma membrane;GO:0120025 plasma membrane bounded cell projection", "go_biological_process": "GO:0001934 positive regulation of protein phosphorylation;GO:0010628 positive regulation of gene expression;GO:0010629 negative regulation of gene expression;GO:0043410 positive regulation of MAPK cascade;GO:0007265 Ras protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "D3ZCS4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZCT5-1", "uniprot_id": "D3ZCT5_RAT", "mass": 96822.0, "length": 857, "protein_name": "Paladin", "gene_name": "Pald1", "organism": "Rat", "refseq_name": "paladin", "refseq_ac": "NP_001029300", "gene_names_uniprotkb": "Pald1", "gene_names_refseq": "Pald1; Pald", "protein_names_uniprotkb": "Paladin", "protein_names_refseq": "paladin", "tax_id": 10116, "disease": "", "pathway": " (rno:294508)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "25159326", "class_list": "", "function": "Data suggest that fascin 1 is involved in localization of actin-bundling proteins paladin and Eps8 (EGF receptor pathway substrate 8) during spermatogenesis; thus, fascin 1 regulates cytoskeletal filaments in Sertoli cells and in spermatid polarity., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZCT5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZCX1-1", "uniprot_id": "D3ZCX1_RAT", "mass": 101743.0, "length": 1009, "protein_name": "Methyl-CpG binding domain protein 6", "gene_name": "Mbd6", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Mbd6", "gene_names_refseq": "", "protein_names_uniprotkb": "Methyl-CpG binding domain protein 6", "protein_names_refseq": "", "tax_id": 10116, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041)", "pathway": " (R-RNO-5689603)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0010369 chromocenter", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZCX1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZD38-1", "uniprot_id": "D3ZD38_RAT", "mass": 19322.0, "length": 173, "protein_name": "Dynein light chain Tctex-type 2B, pseudogene 1", "gene_name": "Dynlt2b-ps1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Dynlt2b-ps1; 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Promotes exon skipping. 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Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm., [UniProtKB, UniProtKB]; Data suggest amechanism by which retrograde semaphorin 3A (Sema3A) signalling regulates the glutamate receptor localization through trafficking of cis-interacting PlexA4 with GluA2 along dendrites. Publication Status: Online-Only, [RefSeq, PubMed]; This is the first detailed description of the cellular and subcellular distribution of PlexinA4 in the adult rat cranial nerves, [RefSeq, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 1, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 2, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 3, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0017154 semaphorin receptor activity", "go_cellular_component": "GO:0002116 semaphorin receptor complex;GO:0005886 plasma membrane;GO:0150053 cerebellar climbing fiber to Purkinje cell synapse", "go_biological_process": "GO:0021615 glossopharyngeal nerve morphogenesis;GO:0007399 nervous system development;GO:0071526 semaphorin-plexin signaling pathway;GO:0048812 neuron projection morphogenesis;GO:0007416 synapse assembly", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "D3ZES7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZEZ6-1", "uniprot_id": "D3ZEZ6_RAT", "mass": 20881.0, "length": 192, "protein_name": "Hepatitis A virus cellular receptor 1 like 2", "gene_name": "Havcr1l2", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Havcr1l2; 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RGD1562402", "gene_names_refseq": "", "protein_names_uniprotkb": "Large ribosomal subunit protein uL15; 60S ribosomal protein L27a", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:499133)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZF07-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZF12-1", "uniprot_id": "D3ZF12_RAT", "mass": 20697.0, "length": 183, "protein_name": "Signal peptidase complex subunit 3", "gene_name": "Spcs3", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Spcs3", "gene_names_refseq": "", "protein_names_uniprotkb": "Signal peptidase complex subunit 3", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-422085); (R-RNO-9768727)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0005787 signal peptidase complex", "go_biological_process": "GO:0019082 viral protein processing;GO:0006508 proteolysis;GO:0045047 protein targeting to ER;GO:0006465 signal peptide processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZF12-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZF63-1", "uniprot_id": "D3ZF63_RAT", "mass": 40388.0, "length": 365, "protein_name": "Protein Wnt", "gene_name": "Wnt9a", "organism": "Rat", "refseq_name": "protein Wnt-9a precursor", "refseq_ac": "NP_001099253", "gene_names_uniprotkb": "Wnt9a", "gene_names_refseq": "Wnt9a", "protein_names_uniprotkb": "Protein Wnt", "protein_names_refseq": "protein Wnt-9a precursor; protein Wnt-9a; wingless related MMTV integration site 9A; wingless-type MMTV integration site 9A; wingless-type MMTV integration site family, member 9A", "tax_id": 10116, "disease": "breast cancer (Disease Ontology:DOID:1612); pancreatic cancer (Disease Ontology:DOID:1793); cholangiocarcinoma (Disease Ontology:DOID:4947)", "pathway": " (rno:287357); (R-RNO-3238698)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15809769", "class_list": "", "function": "5'-flanking promoter region was significantly divergent between human WNT9A and rodent Wnt9a cancer genes., [RefSeq, PubMed]; Ligand for members of the frizzled family of seven transmembrane receptors., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005109 frizzled binding;GO:0005125 cytokine activity;GO:0048018 receptor ligand activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0045880 positive regulation of smoothened signaling pathway;GO:0008285 negative regulation of cell population proliferation;GO:0045597 positive regulation of cell differentiation;GO:0030182 neuron differentiation;GO:0035115 embryonic forelimb morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZF63-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZFE5-1", "uniprot_id": "D3ZFE5_RAT", "mass": 37648.0, "length": 333, "protein_name": "Cathepsin M", "gene_name": "Ctsml1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Ctsml1; Ctsm; RGD1564827", "gene_names_refseq": "", "protein_names_uniprotkb": "Cathepsin M", "protein_names_refseq": "", "tax_id": 10116, "disease": "COVID-19 (Disease Ontology:DOID:0080600); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); alcohol use disorder (Disease Ontology:DOID:1574); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (rno:498689)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004197 cysteine-type endopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005764 lysosome", "go_biological_process": "GO:0051603 proteolysis involved in protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZFE5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZFU9-1", "uniprot_id": "D3ZFU9_RAT", "mass": 214913.0, "length": 1961, "protein_name": "Myosin light chain kinase, smooth muscle", "gene_name": "Mylk", "organism": "Rat", "refseq_name": "myosin light chain kinase, smooth muscle", "refseq_ac": "NP_001099344", "gene_names_uniprotkb": "Mylk", "gene_names_refseq": "Mylk", "protein_names_uniprotkb": "Myosin light chain kinase, smooth muscle; 2.7.11.18; Kinase-related protein; Telokin", "protein_names_refseq": "myosin light chain kinase, smooth muscle; myosin, light polypeptide kinase", "tax_id": 10116, "disease": "megacystis-microcolon-intestinal hypoperistalsis syndrome (Disease Ontology:DOID:0060610); adult respiratory distress syndrome (Disease Ontology:DOID:11394); thoracic aortic aneurysm (Disease Ontology:DOID:14004); asthma (Disease Ontology:DOID:2841); coronary artery disease (Disease Ontology:DOID:3393)", "pathway": " (rno:288057); (R-RNO-445355); (R-RNO-5627123)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "22302242;22673903;29262413;33035716", "class_list": "", "function": "Ang II is involved in the degradation of myosin light chain kinase in pressure overload-induced cardiac hypertrophy and that this process was mediated by MMP9., [RefSeq, PubMed]; Myosin light chain kinase mediates intestinal barrier dysfunction following simulated microgravity based on proteomic strategy., [RefSeq, PubMed]; The expression levels of Myosin light chain kinase in the pylorus and ileum of the diabetic rats were decreased and the changes of Myosin light chain kinase expression in these tissues were partially reversed after treatment with insulin., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.18;2.7.11.1", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0019899 enzyme binding;GO:0046872 metal ion binding;GO:0097110 scaffold protein binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005911 cell-cell junction;GO:0015629 actin cytoskeleton;GO:0030027 lamellipodium", "go_biological_process": "GO:0071476 cellular hypotonic response;GO:0098969 neurotransmitter receptor transport to postsynaptic membrane;GO:0006939 smooth muscle contraction;GO:0030335 positive regulation of cell migration;GO:0071466 cellular response to xenobiotic stimulus", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "D3ZFU9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZGD0-1", "uniprot_id": "D3ZGD0_RAT", "mass": 166213.0, "length": 1498, "protein_name": "Gem-associated protein 5", "gene_name": "Gemin5", "organism": "Rat", "refseq_name": "gem-associated protein 5 isoform X1", "refseq_ac": "XP_006246458", "gene_names_uniprotkb": "Gemin5", "gene_names_refseq": "Gemin5", "protein_names_uniprotkb": "Gem-associated protein 5", "protein_names_refseq": "gem-associated protein 5 isoform X1", "tax_id": 10116, "disease": "neurodevelopmental disorder with cerebellar atrophy and motor dysfunction (Disease Ontology:DOID:0070443)", "pathway": " (R-RNO-191859)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030621 U4 snRNA binding;GO:0003723 RNA binding;GO:0043022 ribosome binding;GO:0000340 RNA 7-methylguanosine cap binding;GO:0003730 mRNA 3'-UTR binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016604 nuclear body", "go_biological_process": "GO:0006417 regulation of translation;GO:0006412 translation;GO:0000387 spliceosomal snRNP assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZGD0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZGH9-1", "uniprot_id": "D3ZGH9_RAT", "mass": 56429.0, "length": 519, "protein_name": "POM121 transmembrane nucleoporin-like 2", "gene_name": "Pom121l2", "organism": "Rat", "refseq_name": "POM121-like protein 2 isoform 2", "refseq_ac": "NP_001156403", "gene_names_uniprotkb": "Pom121l2", "gene_names_refseq": "Pom121l2", "protein_names_uniprotkb": "POM121 transmembrane nucleoporin-like 2", "protein_names_refseq": "POM121 membrane glycoprotein-like 2; POM121-like protein 2 isoform 2; POM121-like protein 2", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0017056 structural constituent of nuclear pore;GO:0008139 nuclear localization sequence binding", "go_cellular_component": "GO:0005643 nuclear pore", "go_biological_process": "GO:0006405 RNA export from nucleus;GO:0006606 protein import into nucleus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZGH9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZGP9-1", "uniprot_id": "DRS7C_RAT", "mass": 34366.0, "length": 311, "protein_name": "Dehydrogenase/reductase SDR family member 7C", "gene_name": "Dhrs7c", "organism": "Rat", "refseq_name": "dehydrogenase/reductase SDR family member 7C isoform 1 precursor", "refseq_ac": "NP_001258527", "gene_names_uniprotkb": "Dhrs7c; Sdr32c2", "gene_names_refseq": "Dhrs7c; RGD1306989", "protein_names_uniprotkb": "Dehydrogenase/reductase SDR family member 7C; 1.1.1.105; Protein SDR32C2; Protein SRP-35; Sarcoplasmic reticulum protein of 35 kDa; Short-chain dehydrogenase/reductase family 32C member 2", "protein_names_refseq": "dehydrogenase/reductase (SDR family) member 7C; dehydrogenase/reductase SDR family member 7C isoform 1 precursor; sarcoplasmic reticulum protein of 35 kDa; short-chain dehydrogenase/reductase family 32C member 2", "tax_id": 10116, "disease": "", "pathway": " (rno:287411)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22143674", "class_list": "", "function": "NADH-dependent oxidoreductase which catalyzes the oxidation of all-trans-retinol to all-trans-retinal. Plays a role in the regulation of cardiac and skeletal muscle metabolic functions. Maintains Ca(2+) intracellular homeostasis by repressing Ca(2+) release from the sarcoplasmic reticulum (SR) in myotubes, possibly through local alternations in NAD/NADH or retinol/retinal. Also plays a role in Ca(2+) homeostasis by controlling Ca(2+) overload in the cytosol and the SR in myotubes. Involved in glucose uptake into skeletal muscles and muscle performance by activating PI3K and mTORC2-mediated AKT1 phosphorylation signaling pathways, possibly through the action of its downstream catalytic product all-trans-retinoic acid., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.1.1.105;1.1.1.62;1.1.1.239;1.1.1.209;1.1.1.53;1.1.1.1;1.1.1.66;1.1.1.315;1.1.1.-", "go_molecular_function": "GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity;GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0016491 oxidoreductase activity", "go_cellular_component": "GO:0033017 sarcoplasmic reticulum membrane;GO:0014801 longitudinal sarcoplasmic reticulum", "go_biological_process": "GO:0006874 intracellular calcium ion homeostasis;GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0098708 D-glucose import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZGP9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZGS1-1", "uniprot_id": "D3ZGS1_RAT", "mass": 88681.0, "length": 779, "protein_name": "Vomeronasal 2 receptor, 54", "gene_name": "Vom2r54", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Vom2r54", "gene_names_refseq": "", "protein_names_uniprotkb": "Vomeronasal 2 receptor, 54", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:691438)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZGS1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZGX8-1", "uniprot_id": "D3ZGX8_RAT", "mass": 177803.0, "length": 1619, "protein_name": "Bromodomain containing 4", "gene_name": "Brd4", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Brd4", "gene_names_refseq": "", "protein_names_uniprotkb": "Bromodomain containing 4", "protein_names_refseq": "", "tax_id": 10116, "disease": "idiopathic pulmonary fibrosis (Disease Ontology:DOID:0050156); Cornelia de Lange syndrome 6 (Disease Ontology:DOID:0060970); nephrocalcinosis (Disease Ontology:DOID:12679); melanoma (Disease Ontology:DOID:1909); colon cancer (Disease Ontology:DOID:219); transitional cell carcinoma (Disease Ontology:DOID:2671); papillary thyroid carcinoma (Disease Ontology:DOID:3969)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0019899 enzyme binding;GO:0000976 transcription cis-regulatory region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000794 condensed nuclear chromosome;GO:0005654 nucleoplasm;GO:0000785 chromatin;GO:0005694 chromosome", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006325 chromatin organization;GO:0006338 chromatin remodeling;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006468 protein phosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZGX8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZH13-1", "uniprot_id": "D3ZH13_RAT", "mass": 34867.0, "length": 307, "protein_name": "Olfactory receptor", "gene_name": "Or5ac19", "organism": "Rat", "refseq_name": "olfactory receptor Olr1538", "refseq_ac": "NP_001000530", "gene_names_uniprotkb": "Or5ac19; Olr1538", "gene_names_refseq": "Olr1538; Or5ac19", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1538; olfactory receptor Olr1538; olfactory receptor gene Olr1538", "tax_id": 10116, "disease": "", "pathway": " (rno:363761)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZH13-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZH71-1", "uniprot_id": "D3ZH71_RAT", "mass": 60399.0, "length": 537, "protein_name": "5,6-dihydroxyindole-2-carboxylic acid oxidase", "gene_name": "Tyrp1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Tyrp1", "gene_names_refseq": "", "protein_names_uniprotkb": "5,6-dihydroxyindole-2-carboxylic acid oxidase; Catalase B; Tyrosinase-related protein 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "oculocutaneous albinism (Disease Ontology:DOID:0050632); oculocutaneous albinism type III (Disease Ontology:DOID:0070097); pigmentation disease (Disease Ontology:DOID:10123)", "pathway": " (R-RNO-5662702)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.14.18.1", "go_molecular_function": "GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity;GO:0046872 metal ion binding;GO:0004503 tyrosinase activity", "go_cellular_component": "GO:0097708 intracellular vesicle;GO:0005737 cytoplasm;GO:0030669 clathrin-coated endocytic vesicle membrane;GO:0042470 melanosome;GO:0010008 endosome membrane", "go_biological_process": "GO:0032438 melanosome organization;GO:0043473 pigmentation;GO:0042438 melanin biosynthetic process;GO:0048023 positive regulation of melanin biosynthetic process;GO:0006582 melanin metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZH71-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZHB3-1", "uniprot_id": "D3ZHB3_RAT", "mass": 15220.0, "length": 137, "protein_name": "40S ribosomal protein S12", "gene_name": "Rps12l1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Rps12l1; LOC100360573", "gene_names_refseq": "", "protein_names_uniprotkb": "40S ribosomal protein S12", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:100360573)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Subunit of the 40S ribosomal complex., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:1990145 maintenance of translational fidelity;GO:0042274 ribosomal small subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZHB3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZHB7-1", "uniprot_id": "D3ZHB7_RAT", "mass": 123969.0, "length": 1083, "protein_name": "Ubiquitin-protein ligase E3C", "gene_name": "Ube3c", "organism": "Rat", "refseq_name": "ubiquitin-protein ligase E3C", "refseq_ac": "NP_001414016", "gene_names_uniprotkb": "Ube3c", "gene_names_refseq": "RGD1559986; Ube3c", "protein_names_uniprotkb": "Ubiquitin-protein ligase E3C; 2.3.2.26; HECT-type ubiquitin transferase E3C; RTA-associated ubiquitin ligase", "protein_names_refseq": "ubiquitin-protein ligase E3C", "tax_id": 10116, "disease": "", "pathway": " (rno:362294); (R-RNO-983168)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "22673903;29393594", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.2.26;2.3.2.32;2.3.2.31;2.3.2.23;2.3.2.27;2.3.2.34;2.3.2.24;2.3.2.-;2.3.2.25", "go_molecular_function": "GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "", "go_biological_process": "GO:0000209 protein polyubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0070936 protein K48-linked ubiquitination;GO:0035519 protein K29-linked ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZHB7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZHD6-1", "uniprot_id": "D3ZHD6_RAT", "mass": 97231.0, "length": 887, "protein_name": "Putative RNA-binding protein 15B", "gene_name": "Rbm15b", "organism": "Rat", "refseq_name": "putative RNA-binding protein 15B", "refseq_ac": "NP_001386249", "gene_names_uniprotkb": "Rbm15b", "gene_names_refseq": "RGD1305937; 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60S ribosomal protein L27a", "protein_names_refseq": "", "tax_id": 10116, "disease": "intrinsic cardiomyopathy (Disease Ontology:DOID:0060036)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZI60-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZI76-1", "uniprot_id": "GPAT2_RAT", "mass": 88969.0, "length": 801, "protein_name": "Glycerol-3-phosphate acyltransferase 2, mitochondrial", "gene_name": "Gpat2", "organism": "Rat", "refseq_name": "glycerol-3-phosphate acyltransferase 2, mitochondrial", "refseq_ac": "NP_001162001", "gene_names_uniprotkb": "Gpat2", "gene_names_refseq": "Gpat2; RGD1304904", "protein_names_uniprotkb": "Glycerol-3-phosphate acyltransferase 2, mitochondrial; 1-acylglycerol-3-phosphate O-acyltransferase GPAT2; 2.3.1.15; 2.3.1.51", "protein_names_refseq": "1-acylglycerol-3-phosphate O-acyltransferase GPAT2; glycerol-3-phosphate acyltransferase 2, mitochondrial", "tax_id": 10116, "disease": "", "pathway": " (rno:296130); (R-RNO-1483166); (R-RNO-75109)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "22673903;22905194", "class_list": "", "function": "GPAT2 expression is linked to arachidonoyl-CoA incorporation into TAG in spermatogenic germ cells, [RefSeq, PubMed]; Transfers an acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate producing a lysophosphatidic acid (LPA), an essential step for the triacylglycerol (TAG) and glycerophospholipids. In vitro also transfers an acyl-group from acyl-ACP to the LPA producing a phosphatidic acid (PA). Prefers arachidonoyl-CoA as the acyl donor. Required for primary processing step during piRNA biosynthesis. Molecular mechanisms by which it promotes piRNA biosynthesis are unclear and do not involve its acyltransferase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.1.51;3.1.1.4;3.1.1.3;2.3.1.15;2.3.1.23;2.3.1.67;2.3.1.25;2.3.1.n7;2.3.1.-", "go_molecular_function": "GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0004366 glycerol-3-phosphate O-acyltransferase activity;GO:0008374 O-acyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0006650 glycerophospholipid metabolic process;GO:0006654 phosphatidic acid biosynthetic process;GO:0019432 triglyceride biosynthetic process;GO:0006072 glycerol-3-phosphate metabolic process;GO:0034587 piRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZI76-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZIJ4-1", "uniprot_id": "D3ZIJ4_RAT", "mass": 128383.0, "length": 1136, "protein_name": "SEL1L family member 3", "gene_name": "Sel1l3", "organism": "Rat", "refseq_name": "protein sel-1 homolog 3", "refseq_ac": "NP_001414256", "gene_names_uniprotkb": "Sel1l3", "gene_names_refseq": "RGD1310366; RGD1562860; Sel1l3", "protein_names_uniprotkb": "SEL1L family member 3", "protein_names_refseq": "protein sel-1 homolog 3; sel-1 suppressor of lin-12-like 3", "tax_id": 10116, "disease": "", "pathway": " (rno:360945)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZIJ4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZIK6-1", "uniprot_id": "D3ZIK6_RAT", "mass": 34545.0, "length": 312, "protein_name": "Olfactory receptor", "gene_name": "Or10aa3", "organism": "Rat", "refseq_name": "olfactory receptor Olr1587", "refseq_ac": "NP_001000913", "gene_names_uniprotkb": "Or10aa3", "gene_names_refseq": "Olr1587; Or10aa3", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1587; olfactory receptor Olr1587; olfactory receptor gene Olr1587", "tax_id": 10116, "disease": "", "pathway": " (rno:405224)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZMW6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZN30-1", "uniprot_id": "D3ZN30_RAT", "mass": 90232.0, "length": 814, "protein_name": "Family with sequence similarity 83, member G", "gene_name": "Fam83g", "organism": "Rat", "refseq_name": "family with sequence similarity 83, member G", "refseq_ac": "NP_001417231", "gene_names_uniprotkb": "Fam83g", "gene_names_refseq": "Fam83g; 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Sdr16c6", "protein_names_uniprotkb": "Short chain dehydrogenase/reductase family 16C, member 6", "protein_names_refseq": "short-chain dehydrogenase/reductase family 16C member 6", "tax_id": 10116, "disease": "", "pathway": " (rno:502939)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor", "go_cellular_component": "GO:0005811 lipid droplet", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZN35-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZNV2-1", "uniprot_id": "TMC5A_RAT", "mass": 33948.0, "length": 288, "protein_name": "Transmembrane and coiled-coil domain-containing protein 5A", "gene_name": "Tmco5a", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Tmco5a; 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Has mainly activity toward iduronyl residues in dermatan sulfate, and toward glucuronyl residues of chondroitin sulfate. Has little to no activity toward desulfated N-resulfated heparin or N-sulfoheparosan., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; The major injury-related change, seen in injured brain and cultured glia, was an increase in 2-O-sulphated HS and increased syndecan-1, suggesting novel approaches to modulating scar formation., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008146 sulfotransferase activity;GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding;GO:0034482 chondroitin 2-sulfotransferase activity;GO:0102142 dermatan 2-sulfotransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0050770 regulation of axonogenesis;GO:0030010 establishment of cell polarity;GO:0050651 dermatan sulfate proteoglycan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZPB6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZPI2-1", "uniprot_id": "D3ZPI2_RAT", "mass": 36249.0, "length": 336, "protein_name": "Proline rich 27", "gene_name": "Prr27", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Prr27; 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PR domain-containing protein 10", "protein_names_refseq": "", "tax_id": 10116, "disease": "Birt-Hogg-Dube syndrome (Disease Ontology:DOID:0050676)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Transcriptional activator, essential for early embryonic development and survival of embryonic stem cells (ESCs). Supports cell growth and survival during early development by transcriptionally activating the expression of the translation initiation factor EIF3B, to sustain global translation. Activates the transcription of FLNC., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000976 transcription cis-regulatory region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0017053 transcription repressor complex;GO:0000785 chromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZQ79-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZQA6-1", "uniprot_id": "D3ZQA6_RAT", "mass": 64758.0, "length": 598, "protein_name": "Putative histone-lysine N-methyltransferase PRDM6", "gene_name": "Prdm6", "organism": "Rat", "refseq_name": "PR/SET domain 6 isoform 1", "refseq_ac": "NP_001419368", "gene_names_uniprotkb": "Prdm6", "gene_names_refseq": "Prdm6; RGD1559594", "protein_names_uniprotkb": "Putative histone-lysine N-methyltransferase PRDM6; 2.1.1.361; PR domain zinc finger protein 6; PR domain-containing protein 6", "protein_names_refseq": "PR domain 6; PR domain containing 6; PR/SET domain 6 isoform 1; putative histone-lysine N-methyltransferase PRDM6", "tax_id": 10116, "disease": "patent ductus arteriosus (Disease Ontology:DOID:13832)", "pathway": " (rno:307305)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Putative histone methyltransferase that acts as a transcriptional repressor of smooth muscle gene expression. Promotes the transition from differentiated to proliferative smooth muscle by suppressing differentiation and maintaining the proliferative potential of vascular smooth muscle cells. Also plays a role in endothelial cells by inhibiting endothelial cell proliferation, survival and differentiation. It is unclear whether it has histone methyltransferase activity in vivo. According to some authors, it does not act as a histone methyltransferase by itself and represses transcription by recruiting EHMT2/G9a. According to others, it possesses histone methyltransferase activity when associated with other proteins and specifically methylates 'Lys-20' of histone H4 in vitro. 'Lys-20' methylation represents a specific tag for epigenetic transcriptional repression., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.1.1.361;2.1.1.362;2.1.1.359;2.1.1.-;2.1.1.355;2.1.1.354", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0140944 histone H4K20 monomethyltransferase activity;GO:0042054 histone methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription;GO:0010468 regulation of gene expression;GO:0032259 methylation;GO:0000122 negative regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZQA6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZQH6-1", "uniprot_id": "D3ZQH6_RAT", "mass": 92923.0, "length": 825, "protein_name": "Phospholipase A2", "gene_name": "Pla2g4d", "organism": "Rat", "refseq_name": "cytosolic phospholipase A2 delta", "refseq_ac": "XP_001080051", "gene_names_uniprotkb": "Pla2g4d", "gene_names_refseq": "Pla2g4d", "protein_names_uniprotkb": "Phospholipase A2; 3.1.1.4", "protein_names_refseq": "cytosolic phospholipase A2 delta", "tax_id": 10116, "disease": "", "pathway": " (rno:691905); (R-RNO-1482788); (R-RNO-1482801); (R-RNO-1482839); (R-RNO-1482922); (R-RNO-1482925); (R-RNO-1483115); (R-RNO-1483166)", "pathway_count": 8, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.1.4;3.1.1.32;2.3.1.-;2.3.1.51;3.1.1.3;3.1.1.-;3.1.1.5;1.11.1.27;2.3.1.23;3.5.1.1;3.1.1.47;3.1.1.13;3.1.1.6;2.3.1.43;3.1.2.22;3.1.2.-;3.1.2.2;3.4.11.-", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0004623 phospholipase A2 activity;GO:0005544 calcium-dependent phospholipid binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0046475 glycerophospholipid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZQH6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZQT0-1", "uniprot_id": "D3ZQT0_RAT", "mass": 36718.0, "length": 338, "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "AABR07071101.1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "AABR07071101.1", "gene_names_refseq": "", "protein_names_uniprotkb": "Glyceraldehyde-3-phosphate dehydrogenase; 1.2.1.12; Peptidyl-cysteine S-nitrosylase GAPDH", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.2.1.12;2.6.99.-", "go_molecular_function": "GO:0051287 NAD binding;GO:0016740 transferase activity;GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005856 cytoskeleton", "go_biological_process": "GO:0006417 regulation of translation;GO:0045087 innate immune response;GO:0006915 apoptotic process;GO:0006094 gluconeogenesis;GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZQT0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZQT5-1", "uniprot_id": "D3ZQT5_RAT", "mass": 35262.0, "length": 319, "protein_name": "Olfactory receptor", "gene_name": "Or13c25", "organism": "Rat", "refseq_name": "olfactory receptor Olr851", "refseq_ac": "NP_001000400", "gene_names_uniprotkb": "Or13c25", "gene_names_refseq": "Olr851; Or13c25", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 851; olfactory receptor Olr851; olfactory receptor gene Olr851", "tax_id": 10116, "disease": "", "pathway": " (rno:298040)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZQT5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZRA8-1", "uniprot_id": "D3ZRA8_RAT", "mass": 55051.0, "length": 505, "protein_name": "Paired box 7", "gene_name": "Pax7", "organism": "Rat", "refseq_name": "paired box protein Pax-7 isoform X1", "refseq_ac": "XP_006239325", "gene_names_uniprotkb": "Pax7", "gene_names_refseq": "Pax7; RGD1564360", "protein_names_uniprotkb": "Paired box 7", "protein_names_refseq": "paired box protein Pax-7 isoform X1", "tax_id": 10116, "disease": "congenital myopathy 19 (Disease Ontology:DOID:0081351); prostate cancer (Disease Ontology:DOID:10283); alveolar rhabdomyosarcoma (Disease Ontology:DOID:4051)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding;GO:1990837 sequence-specific double-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0043403 skeletal muscle tissue regeneration;GO:0014816 skeletal muscle satellite cell differentiation;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZRA8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZRC3-1", "uniprot_id": "D3ZRC3_RAT", "mass": 114651.0, "length": 1017, "protein_name": "RNA-binding protein 26", "gene_name": "Rbm26", "organism": "Rat", "refseq_name": "RNA-binding protein 26 isoform X1", "refseq_ac": "XP_038949332", "gene_names_uniprotkb": "Rbm26; RGD1308297", "gene_names_refseq": "RGD1308297; Rbm26", "protein_names_uniprotkb": "RNA-binding protein 26; RNA-binding motif protein 26", "protein_names_refseq": "RNA-binding protein 26 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-9930044)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "May be involved in the turnover of nuclear polyadenylated (pA+) RNA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZRC3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZRH1-1", "uniprot_id": "D3ZRH1_RAT", "mass": 55287.0, "length": 499, "protein_name": "OXA1L, mitochondrial inner membrane protein", "gene_name": "Oxa1l", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Oxa1l", "gene_names_refseq": "", "protein_names_uniprotkb": "OXA1L, mitochondrial inner membrane protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:691393); (R-RNO-5389840); (R-RNO-5419276); (R-RNO-9937383)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "38843836", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0097177 mitochondrial ribosome binding;GO:0032977 membrane insertase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0031966 mitochondrial membrane;GO:0032991 protein-containing complex", "go_biological_process": "GO:0051262 protein tetramerization;GO:0032981 mitochondrial respiratory chain complex I assembly;GO:0032780 negative regulation of ATP-dependent activity;GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly;GO:0051354 negative regulation of oxidoreductase activity", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "D3ZRH1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZRL3-1", "uniprot_id": "D3ZRL3_RAT", "mass": 16560.0, "length": 150, "protein_name": "Dual specificity protein phosphatase 23", "gene_name": "Dusp23", "organism": "Rat", "refseq_name": "dual specificity protein phosphatase 23", "refseq_ac": "NP_001178759", "gene_names_uniprotkb": "Dusp23", "gene_names_refseq": "Dusp23", "protein_names_uniprotkb": "Dual specificity protein phosphatase 23; 3.1.3.16; 3.1.3.48; Low molecular mass dual specificity phosphatase 3", "protein_names_refseq": "dual specificity protein phosphatase 23", "tax_id": 10116, "disease": "", "pathway": " (rno:360881)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. Able to enhance activation of JNK and p38 (MAPK14)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.3.16;3.1.3.48;3.1.3.53;3.1.3.52;3.1.3.67;3.1.3.-;3.1.3.27;2.7.11.22;3.1.3.74", "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity;GO:0008138 protein tyrosine/serine/threonine phosphatase activity;GO:0016791 phosphatase activity;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0016311 dephosphorylation;GO:0060271 cilium assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZRL3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZRW4-1", "uniprot_id": "D3ZRW4_RAT", "mass": 58006.0, "length": 511, "protein_name": "Potassium voltage-gated channel subfamily A member 10", "gene_name": "Kcna10", "organism": "Rat", "refseq_name": "potassium voltage-gated channel subfamily A member 10", "refseq_ac": "NP_001178642", "gene_names_uniprotkb": "Kcna10", "gene_names_refseq": "Kcna10", "protein_names_uniprotkb": "Potassium voltage-gated channel subfamily A member 10; Voltage-gated potassium channel subunit Kv1.8", "protein_names_refseq": "cyclic GMP gated potassium channel; potassium channel, voltage gated shaker related subfamily A, member 10; potassium voltage-gated channel subfamily A member 10; potassium voltage-gated channel, shaker-related subfamily, member 10", "tax_id": 10116, "disease": "episodic ataxia type 1 (Disease Ontology:DOID:0050989); epilepsy (Disease Ontology:DOID:1826); vestibular disease (Disease Ontology:DOID:3426)", "pathway": " (rno:295360); (R-RNO-1296072)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "12444201", "class_list": "", "function": "KCNA10 protein was easily detectable at the apical membrane of rat proximal tubular cells, and a weaker signal was also evident in the glomerulus., [RefSeq, PubMed]; Voltage-gated potassium ion channel that mediates K(+) permeability of excitable membranes. When opened in response to the voltage difference across the membrane, KCNA10 channel selectively allows the flow of potassium ions across the membrane down their electrochemical gradient., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.8.-.-", "go_molecular_function": "GO:0005251 delayed rectifier potassium channel activity;GO:0005249 voltage-gated potassium channel activity", "go_cellular_component": "GO:0016020 membrane;GO:0008076 voltage-gated potassium channel complex", "go_biological_process": "GO:0051260 protein homooligomerization;GO:0001508 action potential;GO:0006813 potassium ion transport;GO:0071805 potassium ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZRW4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZRW9-1", "uniprot_id": "D3ZRW9_RAT", "mass": 26978.0, "length": 248, "protein_name": "Granzyme N", "gene_name": "Gzmn", "organism": "Rat", "refseq_name": "granzyme N precursor", "refseq_ac": "NP_001178045", "gene_names_uniprotkb": "Gzmn", "gene_names_refseq": "Gzmn; 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AABR07015743.1; RGD1561694", "gene_names_refseq": "Hmgb2l2", "protein_names_uniprotkb": "High mobility group protein B2; High mobility group protein 2", "protein_names_refseq": "high mobility group protein B2-like", "tax_id": 10116, "disease": "", "pathway": " (rno:498388)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000987 cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000785 chromatin", "go_biological_process": "GO:0006310 DNA recombination;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006935 chemotaxis;GO:0010628 positive regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZS25-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZS39-1", "uniprot_id": "D3ZS39_RAT", "mass": 141432.0, "length": 1240, "protein_name": "Protein MMS22-like", "gene_name": "Mms22l", "organism": "Rat", "refseq_name": "protein MMS22-like", "refseq_ac": "NP_001129252", "gene_names_uniprotkb": "Mms22l", "gene_names_refseq": "Mms22l; 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The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication. It mediates the assembly of RAD51 filaments on single-stranded DNA (ssDNA): the MMS22L-TONSL complex is recruited to DSBs following histone replacement by histone chaperones and eviction of the replication protein A complex (RPA/RP-A) from DSBs. Following recruitment to DSBs, the TONSL-MMS22L complex promotes recruitment of RAD51 filaments and subsequent homologous recombination. 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Exosome component 3; Ribosomal RNA-processing protein 40", "protein_names_refseq": "", "tax_id": 10116, "disease": "pontocerebellar hypoplasia type 1B (Disease Ontology:DOID:0060266); stomach cancer (Disease Ontology:DOID:10534)", "pathway": " (R-RNO-429958); (R-RNO-450385); (R-RNO-450513); (R-RNO-450604); (R-RNO-6791226); (R-RNO-9930044)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006396 RNA processing;GO:0006402 mRNA catabolic process;GO:0000956 nuclear-transcribed mRNA catabolic process;GO:0045190 isotype switching;GO:0006364 rRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZT51-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZT59-1", "uniprot_id": "D3ZT59_RAT", "mass": 27041.0, "length": 254, "protein_name": "Sepiapterin reductase", "gene_name": "Spr-ps1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Spr-ps1", "gene_names_refseq": "", "protein_names_uniprotkb": "Sepiapterin reductase; 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RNA-binding motif protein 41", "protein_names_refseq": "RNA-binding protein 41", "tax_id": 10116, "disease": "", "pathway": " (rno:680581)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May bind RNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0097157 pre-mRNA intronic binding;GO:0030626 U12 snRNA binding", "go_cellular_component": "GO:0005689 U12-type spliceosomal complex", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZTA4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZTD1-1", "uniprot_id": "D3ZTD1_RAT", "mass": 103584.0, "length": 942, "protein_name": "Mitogen-activated protein kinase kinase kinase 14", "gene_name": "Map3k14", "organism": "Rat", "refseq_name": "mitogen-activated protein kinase kinase kinase 14", "refseq_ac": "NP_001101771", "gene_names_uniprotkb": "Map3k14", "gene_names_refseq": "Map3k14", "protein_names_uniprotkb": "Mitogen-activated protein kinase kinase kinase 14; 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Or6y1", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1602; olfactory receptor Olr1602; olfactory receptor gene Olr1602", "tax_id": 10116, "disease": "", "pathway": " (rno:405219)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. 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Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0002932 tendon sheath development;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0010628 positive regulation of gene expression;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZUL2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZUP1-1", "uniprot_id": "D3ZUP1_RAT", "mass": 22630.0, "length": 223, "protein_name": "Keratin associated protein 10-8 like 1", "gene_name": "Krtap10-8l1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Krtap10-8l1; LOC100365646", "gene_names_refseq": "", "protein_names_uniprotkb": "Keratin associated protein 10-8 like 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0045095 keratin filament", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZUP1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZUQ1-1", "uniprot_id": "D3ZUQ1_RAT", "mass": 44554.0, "length": 398, "protein_name": "Lipase", "gene_name": "Lipo1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Lipo1", "gene_names_refseq": "", "protein_names_uniprotkb": "Lipase", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:294097)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004771 sterol ester esterase activity", "go_cellular_component": "", "go_biological_process": "GO:0016042 lipid catabolic process;GO:0016125 sterol metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZUQ1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZUQ8-1", "uniprot_id": "D3ZUQ8_RAT", "mass": 377505.0, "length": 3431, "protein_name": "SZT2 subunit of KICSTOR complex", "gene_name": "Szt2", "organism": "Rat", "refseq_name": "KICSTOR complex protein SZT2", "refseq_ac": "NP_001414527", "gene_names_uniprotkb": "Szt2", "gene_names_refseq": "RGD1308616; 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Or52ae8b", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 121; olfactory receptor Olr121; olfactory receptor gene Olr121", "tax_id": 10116, "disease": "metabolic dysfunction-associated steatohepatitis (Disease Ontology:DOID:0080547); gestational diabetes (Disease Ontology:DOID:11714); middle cerebral artery infarction (Disease Ontology:DOID:3525); pancreatitis (Disease Ontology:DOID:4989)", "pathway": " (rno:293257)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZV48-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZV75-1", "uniprot_id": "D3ZV75_RAT", "mass": 51201.0, "length": 464, "protein_name": "Lysosomal dipeptide transporter MFSD1", "gene_name": "Mfsd1", "organism": "Rat", "refseq_name": "major facilitator superfamily domain-containing protein 1", "refseq_ac": "NP_001178776", "gene_names_uniprotkb": "Mfsd1", "gene_names_refseq": "Mfsd1; RGD1305751", "protein_names_uniprotkb": "Lysosomal dipeptide transporter MFSD1; Major facilitator superfamily domain-containing protein 1", "protein_names_refseq": "major facilitator superfamily domain-containing protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:361957)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Lysosomal dipeptide uniporter that selectively exports lysine, arginine or histidine-containing dipeptides with a net positive charge from the lysosome lumen into the cytosol. Could play a role in a specific type of protein O-glycosylation indirectly regulating macrophages migration and tissue invasion. Also essential for liver homeostasis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0160178 dipeptide uniporter activity", "go_cellular_component": "GO:0005764 lysosome;GO:0005765 lysosomal membrane", "go_biological_process": "GO:0050821 protein stabilization;GO:0061462 protein localization to lysosome;GO:0141204 dipeptide transmembrane transport from lysosomal lumen to cytosol", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZV75-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZV96-1", "uniprot_id": "D3ZV96_RAT", "mass": 34562.0, "length": 310, "protein_name": "LRAT domain containing 2", "gene_name": "Lratd2", "organism": "Rat", "refseq_name": "protein LRATD2", "refseq_ac": "NP_001385651", "gene_names_uniprotkb": "Lratd2", "gene_names_refseq": "Fam84b; Lratd2; RGD1562236", "protein_names_uniprotkb": "LRAT domain containing 2", "protein_names_refseq": "family with sequence similarity 84, member B; protein LRATD2", "tax_id": 10116, "disease": "", "pathway": " (rno:120093666)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZV96-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZVI5-1", "uniprot_id": "D3ZVI5_RAT", "mass": 64300.0, "length": 591, "protein_name": "Eyes absent homolog", "gene_name": "Eya1", "organism": "Rat", "refseq_name": "eyes absent homolog 1", "refseq_ac": "NP_001413950", "gene_names_uniprotkb": "Eya1", "gene_names_refseq": "Eya1", "protein_names_uniprotkb": "Eyes absent homolog; 3.1.3.48", "protein_names_refseq": "eyes absent 1 homolog; eyes absent homolog 1", "tax_id": 10116, "disease": "branchiootic syndrome 1 (Disease Ontology:DOID:0061209); branchiootorenal syndrome 1 (Disease Ontology:DOID:0111423); branchiootorenal syndrome (Disease Ontology:DOID:14702); eye disease (Disease Ontology:DOID:5614); mitochondrial myopathy (Disease Ontology:DOID:699)", "pathway": " (R-RNO-5693565)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "24528972", "class_list": "", "function": "Downregulation of Eya1 and Six1 gene expression in nitrofen-induced PH suggests that decreased Eya1 and Six1 expression during the late pseudoglandular stage may interfere with epithelial branching and distal airway maturation, thus resulting in PH., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.3.48;2.7.10.1;3.1.3.16;3.1.3.2;2.7.11.1;3.1.3.21;3.1.3.18;3.1.3.67;3.1.3.-;3.1.3.27;3.1.3.5;2.3.1.48;2.3.1.-;3.6.-.-;3.1.-.-", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004725 protein tyrosine phosphatase activity;GO:0003723 RNA binding;GO:0140793 histone H2AXY142 phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0016604 nuclear body;GO:0032993 protein-DNA complex", "go_biological_process": "GO:0006281 DNA repair;GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0045739 positive regulation of DNA repair;GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZVI5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZVQ1-1", "uniprot_id": "D3ZVQ1_RAT", "mass": 72139.0, "length": 646, "protein_name": "Centrosomal protein of 72 kDa", "gene_name": "Cep72", "organism": "Rat", "refseq_name": "centrosomal protein of 72 kDa", "refseq_ac": "NP_001387005", "gene_names_uniprotkb": "Cep72", "gene_names_refseq": "Cep72; RGD1566336", "protein_names_uniprotkb": "Centrosomal protein of 72 kDa", "protein_names_refseq": "centrosomal protein 72kDa; centrosomal protein of 72 kDa", "tax_id": 10116, "disease": "", "pathway": " (rno:308064); (R-RNO-2565942); (R-RNO-380259); (R-RNO-380270); (R-RNO-380284); (R-RNO-380320); (R-RNO-5620912); (R-RNO-8854518)", "pathway_count": 8, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in the recruitment of key centrosomal proteins to the centrosome. Provides centrosomal microtubule-nucleation activity on the gamma-tubulin ring complexes (gamma-TuRCs) and has critical roles in forming a focused bipolar spindle, which is needed for proper tension generation between sister chromatids. Required for localization of KIZ, AKAP9 and gamma-tubulin ring complexes (gamma-TuRCs). Involved in centriole duplication. Required for CDK5RAP22, CEP152, WDR62 and CEP63 centrosomal localization and promotes the centrosomal localization of CDK2., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding", "go_cellular_component": "GO:0005813 centrosome;GO:0034451 centriolar satellite", "go_biological_process": "GO:0007051 spindle organization;GO:0007099 centriole replication;GO:0033566 gamma-tubulin complex localization;GO:1904779 regulation of protein localization to centrosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZVQ1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZVR8-1", "uniprot_id": "D3ZVR8_RAT", "mass": 57825.0, "length": 525, "protein_name": "Protein phosphatase 1 regulatory inhibitor subunit 16B", "gene_name": "Ppp1r16a", "organism": "Rat", "refseq_name": "protein phosphatase 1 regulatory subunit 16A isoform X1", "refseq_ac": "XP_063119946", "gene_names_uniprotkb": "Ppp1r16a", "gene_names_refseq": "Ppp1r16a", "protein_names_uniprotkb": "Protein phosphatase 1 regulatory inhibitor subunit 16B; CAAX box protein TIMAP; TGF-beta-inhibited membrane-associated protein", "protein_names_refseq": "protein phosphatase 1 regulatory subunit 16A isoform X1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019888 protein phosphatase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005886 plasma membrane;GO:0042995 cell projection", "go_biological_process": "GO:0061028 establishment of endothelial barrier", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZVR8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZVU7-1", "uniprot_id": "D3ZVU7_RAT", "mass": 55260.0, "length": 484, "protein_name": "Histone deacetylase 1", "gene_name": "Hdac1l", "organism": "Rat", "refseq_name": "histone deacetylase 1-like", "refseq_ac": "NP_445898", "gene_names_uniprotkb": "Hdac1l", "gene_names_refseq": "Hdac1l", "protein_names_uniprotkb": "Histone deacetylase 1; 3.5.1.98; HD1", "protein_names_refseq": "histone deacetylase 1-like", "tax_id": 10116, "disease": "glaucoma (Disease Ontology:DOID:1686); multiple sclerosis (Disease Ontology:DOID:2377); breast carcinoma (Disease Ontology:DOID:3459); pancreatic ductal carcinoma (Disease Ontology:DOID:3587); pulmonary hypertension (Disease Ontology:DOID:6432); prostate carcinoma in situ (Disease Ontology:DOID:8634); cervix uteri carcinoma in situ (Disease Ontology:DOID:8991); colorectal cancer (Disease Ontology:DOID:9256); type 1 diabetes mellitus (Disease Ontology:DOID:9744); alopecia areata (Disease Ontology:DOID:986); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (rno:84576)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "12032080", "class_list": "", "function": "Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also functions as deacetylase for non-histone proteins., [UniProtKB, UniProtKB]; Loss of HDAC1 in mouse embryonic stem cells results in reduced proliferation., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 11, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.5.1.98;3.5.1.-;2.3.2.-;3.5.1.48;3.5.1.62", "go_molecular_function": "GO:0003682 chromatin binding;GO:0046872 metal ion binding;GO:0004407 histone deacetylase activity;GO:0140297 DNA-binding transcription factor binding;GO:0160008 protein decrotonylase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016581 NuRD complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0008284 positive regulation of cell population proliferation;GO:0043066 negative regulation of apoptotic process;GO:0048714 positive regulation of oligodendrocyte differentiation;GO:0048511 rhythmic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZVU7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZVY9-1", "uniprot_id": "D3ZVY9_RAT", "mass": 7731.0, "length": 72, "protein_name": "Guanine nucleotide-binding protein subunit gamma", "gene_name": "Gng14", "organism": "Rat", "refseq_name": "putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14", "refseq_ac": "NP_001387933", "gene_names_uniprotkb": "Gng14; LOC685513", "gene_names_refseq": "Gng14", "protein_names_uniprotkb": "Guanine nucleotide-binding protein subunit gamma", "protein_names_refseq": "putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14", "tax_id": 10116, "disease": "obesity (Disease Ontology:DOID:9970)", "pathway": " (rno:685513)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0031681 G-protein beta-subunit binding", "go_cellular_component": "GO:0005834 heterotrimeric G-protein complex", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZVY9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZW38-1", "uniprot_id": "D3ZW38_RAT", "mass": 28399.0, "length": 272, "protein_name": "Exosome complex component MTR3", "gene_name": "Exosc6", "organism": "Rat", "refseq_name": "exosome complex component MTR3", "refseq_ac": "NP_001387896", "gene_names_uniprotkb": "Exosc6", "gene_names_refseq": "Exosc6", "protein_names_uniprotkb": "Exosome complex component MTR3; Exosome component 6; mRNA transport regulator 3 homolog", "protein_names_refseq": "exosome complex component MTR3; exosome complex exonuclease MTR3", "tax_id": 10116, "disease": "", "pathway": " (rno:307850); (R-RNO-429958); (R-RNO-450385); (R-RNO-450513); (R-RNO-450604); (R-RNO-6791226); (R-RNO-9930044)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005829 cytosol;GO:0000176 nuclear exosome (RNase complex);GO:0000177 cytoplasmic exosome (RNase complex)", "go_biological_process": "GO:0071028 nuclear mRNA surveillance;GO:0006396 RNA processing;GO:0045190 isotype switching;GO:0006364 rRNA processing;GO:0016075 rRNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZW38-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZWF4-1", "uniprot_id": "D3ZWF4_RAT", "mass": 64040.0, "length": 580, "protein_name": "Proline rich 14", "gene_name": "Prr14", "organism": "Rat", "refseq_name": "proline-rich protein 14", "refseq_ac": "NP_001388630", "gene_names_uniprotkb": "Prr14", "gene_names_refseq": "AABR07005779.1; 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Permeable to bicarbonate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "7.6.2.2;7.6.2.3;7.6.2.-;5.6.1.6;1.11.1.-;1.8.-.-;1.8.5.1", "go_molecular_function": "GO:0005229 intracellularly calcium-gated chloride channel activity;GO:0005254 chloride channel activity;GO:0160133 bicarbonate channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0034707 chloride channel complex", "go_biological_process": "GO:1902476 chloride transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZX44-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZX89-1", "uniprot_id": "D3ZX89_RAT", "mass": 17282.0, "length": 160, "protein_name": "RGD1563302", "gene_name": "RGD1563302", "organism": "Rat", "refseq_name": "uncharacterized protein LOC361049", "refseq_ac": "NP_001156371", "gene_names_uniprotkb": "RGD1563302", "gene_names_refseq": "RGD1563302", "protein_names_uniprotkb": "RGD1563302", "protein_names_refseq": "uncharacterized protein LOC361049", "tax_id": 10116, "disease": "", "pathway": " (rno:361049)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZX89-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZXF9-1", "uniprot_id": "D3ZXF9_RAT", "mass": 29441.0, "length": 276, "protein_name": "Large ribosomal subunit protein bL12m", "gene_name": "Mrpl12", "organism": "Rat", "refseq_name": "large ribosomal subunit protein bL12m", "refseq_ac": "NP_001025071", "gene_names_uniprotkb": "Mrpl12", "gene_names_refseq": "Mrpl12; Rpm12", "protein_names_uniprotkb": "Large ribosomal subunit protein bL12m; 39S ribosomal protein L12, mitochondrial", "protein_names_refseq": "39S ribosomal protein L12, mitochondrial; large ribosomal subunit protein bL12m; ribosomal protein, mitochondrial, L12", "tax_id": 10116, "disease": "combined oxidative phosphorylation deficiency 45 (Disease Ontology:DOID:0112113)", "pathway": " (rno:303746); (R-RNO-5389840); (R-RNO-5419276); (R-RNO-9837999); (R-RNO-9937383)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "As a component of the mitochondrial large ribosomal subunit, plays a role in mitochondrial translation. When present in mitochondria as a free protein not associated with the ribosome, associates with mitochondrial RNA polymerase POLRMT to activate transcription. Required for POLRMT stability., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0045893 positive regulation of DNA-templated transcription;GO:0006412 translation;GO:0006390 mitochondrial transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZXF9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZXQ5-1", "uniprot_id": "D3ZXQ5_RAT", "mass": 238704.0, "length": 2136, "protein_name": "Tudor domain-containing protein 6", "gene_name": "Tdrd6", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Tdrd6", "gene_names_refseq": "", "protein_names_uniprotkb": "Tudor domain-containing protein 6", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:316254)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Tudor domain-containing protein involved in germ cell development, more specifically the formation of chromatoid body (during spermiogenesis), Balbiani body (during oogenesis), germ plasm (upon fertilization), and for proper miRNA expression and spliceosome maturation. Essential for RNA-dependent helicase UPF1 localization to chromatoid body, for UPF1-UPF2 and UPF1-DDX4 interactions which are required for mRNA degradation, using the extended 3' UTR-triggered nonsense-mediated mRNA decay (NMD) pathway. Involved in spliceosome maturation and mRNA splicing in prophase I spermatocytes through interaction with arginine N-methyltransferase PRMT5 and symmetrically arginine dimethylated SNRPB (small nuclear ribonucleoprotein-associated protein)., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0045202 synapse;GO:1990904 ribonucleoprotein complex;GO:0033391 chromatoid body", "go_biological_process": "GO:0030719 P granule organization;GO:0007283 spermatogenesis;GO:0007281 germ cell development;GO:0000387 spliceosomal snRNP assembly;GO:0034587 piRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZXQ5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZXR2-1", "uniprot_id": "D3ZXR2_RAT", "mass": 212596.0, "length": 1845, "protein_name": "Cilia- and flagella-associated protein 44", "gene_name": "Cfap44", "organism": "Rat", "refseq_name": "cilia- and flagella-associated protein 44", "refseq_ac": "NP_001128062", "gene_names_uniprotkb": "Cfap44; 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Ndufa4l2", "gene_names_refseq": "Coxfa4l2; Ndufa4l2", "protein_names_uniprotkb": "NDUFA4, mitochondrial complex associated like 2", "protein_names_refseq": "NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2; NDUFA4, mitochondrial complex associated like 2; rCG59612-like", "tax_id": 10116, "disease": "", "pathway": " (rno:100362331)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "28429857;31740659;33340241", "class_list": "", "function": "NDUFA4L2 in smooth muscle promotes vascular remodeling in hypoxic pulmonary arterial hypertension., [RefSeq, PubMed]; NDUFA4L2 protects against H/R injury by preventing myocardium apoptosis and mitochondrial dysfunction via the complex I, [RefSeq, PubMed]; The results demonstrated that the upregulation of NDUFA4L2 ameliorated the apoptosis of NP cells by repressing excessive mitophagy, which ultimately alleviated IVDD. These findings show for the first time that NDUFA4L2 and mitophagy may be potential therapeutic targets for IVDD. 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RGD1560155", "protein_names_uniprotkb": "Disco-interacting protein 2 homolog C", "protein_names_refseq": "disco-interacting protein 2 homolog C isoform X3", "tax_id": 10116, "disease": "", "pathway": " (rno:307067)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZZB0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZZB2-1", "uniprot_id": "D3ZZB2_RAT", "mass": 142549.0, "length": 1292, "protein_name": "Peroxisomal ATPase PEX1", "gene_name": "Pex1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Pex1", "gene_names_refseq": "", "protein_names_uniprotkb": "Peroxisomal ATPase PEX1; Peroxin-1; Peroxisome biogenesis factor 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "peroxisomal biogenesis disorder (Disease Ontology:DOID:0080377); peroxisome biogenesis disorder 1A (Disease Ontology:DOID:0080476); Heimler syndrome 1 (Disease Ontology:DOID:0080623); peroxisome biogenesis disorder 1B (Disease Ontology:DOID:0081240); Zellweger syndrome (Disease Ontology:DOID:905)", "pathway": " (rno:500006); (R-RNO-9033241)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling. Specifically recognizes PEX5 monoubiquitinated at 'Cys-11', and pulls it out of the peroxisome lumen through the PEX2-PEX10-PEX12 retrotranslocation channel. Extraction by the PEX1-PEX6 AAA ATPase complex is accompanied by unfolding of the TPR repeats and release of bound cargo from PEX5., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.6.2.3;3.6.4.13;3.6.4.12;2.7.11.1;3.6.1.5;3.6.4.10;3.6.4.-;2.3.2.27;5.6.2.4;3.6.5.-;5.6.2.-;3.1.-.-;2.7.7.7;2.7.7.49;3.1.13.1;4.2.99.18;7.6.2.2;7.6.2.3;7.6.2.-;5.6.1.6;7.2.2.-;3.6.1.15;3.6.4.6;3.1.3.1;3.9.1.1;6.1.1.12;3.6.1.-;2.7.4.3;3.1.4.-;3.4.24.-;3.6.-.-;3.4.21.53;5.6.2.5", "go_molecular_function": "GO:0140036 ubiquitin-modified protein reader activity;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0044877 protein-containing complex binding;GO:0140318 protein transporter activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005777 peroxisome;GO:0005778 peroxisomal membrane;GO:0005829 cytosol;GO:1904949 ATPase complex", "go_biological_process": "GO:0043335 protein unfolding;GO:0007031 peroxisome organization;GO:0006625 protein targeting to peroxisome;GO:0016558 protein import into peroxisome matrix;GO:0060152 microtubule-based peroxisome localization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZZB2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZZD5-1", "uniprot_id": "D3ZZD5_RAT", "mass": 51495.0, "length": 457, "protein_name": "MINDY family member 4B", "gene_name": "Mindy4b", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Mindy4b", "gene_names_refseq": "", "protein_names_uniprotkb": "MINDY family member 4B", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity;GO:1990380 K48-linked deubiquitinase activity", "go_cellular_component": "", "go_biological_process": "GO:0071108 protein K48-linked deubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZZD5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZZH5-1", "uniprot_id": "D3ZZH5_RAT", "mass": 53801.0, "length": 489, "protein_name": "Inhibitory synaptic factor family member 2B", "gene_name": "Insyn2b", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Insyn2b", "gene_names_refseq": "", "protein_names_uniprotkb": "Inhibitory synaptic factor family member 2B", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:100361460)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, 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"ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZZH5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZZK7-1", "uniprot_id": "D3ZZK7_RAT", "mass": 185864.0, "length": 1622, "protein_name": "Myosin-IIIa", "gene_name": "Myo3a", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Myo3a", "gene_names_refseq": "", "protein_names_uniprotkb": "Myosin-IIIa; 2.7.11.1", "protein_names_refseq": "", "tax_id": 10116, "disease": "autosomal dominant nonsyndromic deafness 90 (Disease Ontology:DOID:0070607); autosomal recessive nonsyndromic deafness 30 (Disease Ontology:DOID:0110489)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.6.2.3;2.7.11.1;3.6.4.13;2.7.12.1;3.6.4.12;2.7.1.153;2.7.1.137;3.6.1.5;2.7.11.24;2.7.11.25;2.7.11.22;2.7.11.23;3.6.4.10;3.6.4.-;2.7.4.6;2.3.2.27;2.7.1.154;2.7.11.38;2.7.11.17;2.7.11.21;2.7.12.2;5.6.2.4;2.7.1.40;2.7.11.12;3.6.5.-;2.7.11.26;5.6.2.-;2.7.11.34;3.1.-.-;2.7.10.2;2.7.1.150;2.7.11.13;2.7.7.7;2.7.7.49;3.1.13.1;4.2.99.18;4.1.1.32;7.6.2.2;7.6.2.3;7.6.2.-;5.6.1.6;7.2.2.-;3.6.1.15;3.6.4.6;3.1.3.1;3.9.1.1;2.7.11.19;6.1.1.12;2.7.2.3;2.7.11.11;3.6.1.-;2.7.11.31;3.1.3.16;2.7.11.4;2.3.1.48;3.1.11.-;2.7.13.3;2.7.4.18;3.1.24.-;2.7.4.3;3.4.19.12;2.7.11.39;3.1.4.-;3.4.24.-;3.6.-.-;2.4.99.18;3.4.21.53;5.6.2.5;2.7.11.10", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0015629 actin cytoskeleton;GO:0030175 filopodium;GO:0001917 photoreceptor inner segment;GO:0031941 filamentous actin", "go_biological_process": "GO:0030832 regulation of actin filament length;GO:0007601 visual perception;GO:0046777 protein autophosphorylation;GO:0007605 sensory perception of sound;GO:0018107 peptidyl-threonine phosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZZK7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZZQ5-1", "uniprot_id": "D3ZZQ5_RAT", "mass": 27242.0, "length": 237, "protein_name": "N-alpha-acetyltransferase 40", "gene_name": "Naa40", "organism": "Rat", "refseq_name": "N-alpha-acetyltransferase 40", "refseq_ac": "NP_001101988", "gene_names_uniprotkb": "Naa40", "gene_names_refseq": "Naa40; Nat11; RGD1565838", "protein_names_uniprotkb": "N-alpha-acetyltransferase 40; 2.3.1.257; N-acetyltransferase 11; N-alpha-acetyltransferase D; Protein acetyltransferase 1", "protein_names_refseq": "N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog; N-acetyltransferase 11; N-alpha-acetyltransferase 40", "tax_id": 10116, "disease": "", "pathway": " (rno:361718)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "N-alpha-acetyltransferase that specifically mediates the acetylation of the N-terminal residues of histones H4 and H2A. In contrast to other N-alpha-acetyltransferase, has a very specific selectivity for histones H4 and H2A N-terminus and specifically recognizes the 'Ser-Gly-Arg-Gly sequence'. Acts as a negative regulator of apoptosis. May play a role in hepatic lipid metabolism., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.1.257", "go_molecular_function": "GO:0010485 histone H4 acetyltransferase activity;GO:0043998 histone H2A acetyltransferase activity;GO:1990189 protein N-terminal-serine acetyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZZQ5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZZV5-1", "uniprot_id": "D3ZZV5_RAT", "mass": 35843.0, "length": 316, "protein_name": "Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7", "gene_name": "Jmjd7", "organism": "Rat", "refseq_name": "bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7", "refseq_ac": "NP_001108128", "gene_names_uniprotkb": "Jmjd7", "gene_names_refseq": "Jmjd7", "protein_names_uniprotkb": "Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7; 1.14.11.63; JmjC domain-containing protein 7; Jumonji domain-containing protein 7", "protein_names_refseq": "bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7; jmjC domain-containing protein 7", "tax_id": 10116, "disease": "alcohol use disorder (Disease Ontology:DOID:1574)", "pathway": " (rno:100137086); (R-RNO-9629569)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Bifunctional enzyme that acts both as an endopeptidase and 2-oxoglutarate-dependent monooxygenase. Endopeptidase that cleaves histones N-terminal tails at the carboxyl side of methylated arginine or lysine residues, to generate 'tailless nucleosomes', which may trigger transcription elongation. Preferentially recognizes and cleaves monomethylated and dimethylated arginine residues of histones H2, H3 and H4. After initial cleavage, continues to digest histones tails via its aminopeptidase activity. Additionally, may play a role in protein biosynthesis by modifying the translation machinery. Acts as a Fe(2+) and 2-oxoglutarate-dependent monooxygenase, catalyzing (S)-stereospecific hydroxylation at C-3 of 'Lys-22' of DRG1 and 'Lys-21' of DRG2 translation factors (TRAFAC), promoting their interaction with ribonucleic acids (RNA)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.14.11.63", "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0046872 metal ion binding;GO:0004177 aminopeptidase activity;GO:0016706 2-oxoglutarate-dependent dioxygenase activity;GO:0004497 monooxygenase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0018126 protein hydroxylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZZV5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A0T8-1", "uniprot_id": "D4A0T8_RAT", "mass": 38311.0, "length": 338, "protein_name": "Dehydrogenase/reductase 7", "gene_name": "Dhrs7", "organism": "Rat", "refseq_name": "dehydrogenase/reductase SDR family member 7", "refseq_ac": "NP_001258323", "gene_names_uniprotkb": "Dhrs7; RGD1565002", "gene_names_refseq": "Dhrs7; RGD1565002", "protein_names_uniprotkb": "Dehydrogenase/reductase 7", "protein_names_refseq": "dehydrogenase/reductase (SDR family) member 7; dehydrogenase/reductase SDR family member 7", "tax_id": 10116, "disease": "", "pathway": " (rno:299135)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity;GO:0004090 carbonyl reductase (NADPH) activity;GO:0016491 oxidoreductase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A0T8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A0V7-1", "uniprot_id": "D4A0V7_RAT", "mass": 52022.0, "length": 448, "protein_name": "Cation channel, sperm associated 4", "gene_name": "Catsper4", "organism": "Rat", "refseq_name": "cation channel, sperm associated 4 isoform 1", "refseq_ac": "NP_001418108", "gene_names_uniprotkb": "Catsper4", "gene_names_refseq": "Catsper4; RGD1565213", "protein_names_uniprotkb": "Cation channel, sperm associated 4", "protein_names_refseq": "cation channel sperm-associated protein 4; cation channel, sperm associated 4 isoform 1; channel, sperm associated 4", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-1300642)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005227 calcium-activated cation channel activity;GO:0005245 voltage-gated calcium channel activity", "go_cellular_component": "GO:0036128 CatSper complex;GO:0001669 acrosomal vesicle;GO:0097228 sperm principal piece", "go_biological_process": "GO:0030317 flagellated sperm motility;GO:0048240 sperm capacitation;GO:0006814 sodium ion transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A0V7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A0Y6-1", "uniprot_id": "D4A0Y6_RAT", "mass": 343696.0, "length": 3121, "protein_name": "Marker of proliferation Ki-67", "gene_name": "Mki67", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Mki67", "gene_names_refseq": "", "protein_names_uniprotkb": "Marker of proliferation Ki-67", "protein_names_refseq": "", "tax_id": 10116, "disease": "diffuse large B-cell lymphoma (Disease Ontology:DOID:0050745); mucositis (Disease Ontology:DOID:0080178); graft-versus-host disease (Disease Ontology:DOID:0081267); prostate carcinoma (Disease Ontology:DOID:10286); stomach cancer (Disease Ontology:DOID:10534); urinary bladder cancer (Disease Ontology:DOID:11054); neutropenia (Disease Ontology:DOID:1227); leiomyoma (Disease Ontology:DOID:127); lung cancer (Disease Ontology:DOID:1324); interstitial cystitis (Disease Ontology:DOID:13949); alcohol use disorder (Disease Ontology:DOID:1574); breast cancer (Disease Ontology:DOID:1612); pancreatic cancer (Disease Ontology:DOID:1793); colon cancer (Disease Ontology:DOID:219); high grade glioma (Disease Ontology:DOID:3070); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); cholangiocarcinoma (Disease Ontology:DOID:4947); adult pineal parenchymal tumor (Disease Ontology:DOID:5031); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); kidney disease (Disease Ontology:DOID:557); hepatoblastoma (Disease Ontology:DOID:687); in situ carcinoma (Disease Ontology:DOID:8719); Crohn's disease (Disease Ontology:DOID:8778); psoriasis (Disease Ontology:DOID:8893); systemic lupus erythematosus (Disease Ontology:DOID:9074); Barrett's esophagus (Disease Ontology:DOID:9206); colorectal cancer (Disease Ontology:DOID:9256); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 29, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0140693 molecular condensate scaffold activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0000775 chromosome, centromeric region", "go_biological_process": "GO:0072574 hepatocyte proliferation;GO:0007059 chromosome segregation;GO:0008283 cell population proliferation;GO:0034605 cellular response to heat;GO:0006259 DNA metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A0Y6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A0Z7-1", "uniprot_id": "D4A0Z7_RAT", "mass": 121067.0, "length": 1109, "protein_name": "Brother of CDO", "gene_name": "Boc", "organism": "Rat", "refseq_name": "brother of CDO isoform X2", "refseq_ac": "XP_017453648", "gene_names_uniprotkb": "Boc", "gene_names_refseq": "Boc", "protein_names_uniprotkb": "Brother of CDO", "protein_names_refseq": "brother of CDO isoform X2", "tax_id": 10116, "disease": "", "pathway": " (rno:360715); (R-RNO-525793)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0030426 growth cone;GO:0043025 neuronal cell body;GO:0044295 axonal growth cone", "go_biological_process": "GO:0007399 nervous system development;GO:0098609 cell-cell adhesion;GO:0030030 cell projection organization;GO:0007224 smoothened signaling pathway;GO:0007411 axon guidance", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A0Z7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A165-1", "uniprot_id": "D4A165_RAT", "mass": 56544.0, "length": 508, "protein_name": "Serine/threonine-protein kinase 33", "gene_name": "Stk33", "organism": "Rat", "refseq_name": "serine/threonine-protein kinase 33", "refseq_ac": "NP_001419557", "gene_names_uniprotkb": "Stk33", "gene_names_refseq": "Stk33", "protein_names_uniprotkb": "Serine/threonine-protein kinase 33; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase 33", "tax_id": 10116, "disease": "spermatogenic failure 93 (Disease Ontology:DOID:0070592); depressive disorder (Disease Ontology:DOID:1596); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (rno:690861)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "24057876", "class_list": "", "function": "Double-immunostaining experiments with antibodies against Stk33 and vimentin showed a striking colocalization of Stk33 and vimentin in the hypothalamus., [RefSeq, PubMed]; Serine/threonine protein kinase required for spermatid differentiation and male fertility. Promotes sperm flagella assembly during spermatogenesis by mediating phosphorylation of fibrous sheath proteins AKAP3 and AKAP4. Also phosphorylates vimentin/VIM, thereby regulating the dynamic behavior of the intermediate filament cytoskeleton., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0048471 perinuclear region of cytoplasm;GO:0002177 manchette", "go_biological_process": "GO:0044773 mitotic DNA damage checkpoint signaling;GO:0007283 spermatogenesis;GO:0046777 protein autophosphorylation;GO:0018107 peptidyl-threonine phosphorylation;GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A165-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A189-1", "uniprot_id": "D4A189_RAT", "mass": 22058.0, "length": 187, "protein_name": "Calcium and integrin binding family member 3", "gene_name": "Cib3", "organism": "Rat", "refseq_name": "calcium and integrin-binding family member 3", "refseq_ac": "NP_001178010", "gene_names_uniprotkb": "Cib3", "gene_names_refseq": "Cib3", "protein_names_uniprotkb": "Calcium and integrin binding family member 3", "protein_names_refseq": "calcium and integrin-binding family member 3", "tax_id": 10116, "disease": "", "pathway": " (rno:685723)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0042383 sarcolemma", "go_biological_process": "GO:0055074 calcium ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A189-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A1C2-1", "uniprot_id": "D4A1C2_RAT", "mass": 42185.0, "length": 379, "protein_name": "Junctional adhesion molecule-like", "gene_name": "Jaml", "organism": "Rat", "refseq_name": "junction adhesion molecule like precursor", "refseq_ac": "NP_001416597", "gene_names_uniprotkb": "Jaml; Amica1", "gene_names_refseq": "Amica1; Jaml; RGD1562572", "protein_names_uniprotkb": "Junctional adhesion molecule-like", "protein_names_refseq": "adhesion molecule, interacts with CXADR antigen 1; junction adhesion molecule like precursor; junctional adhesion molecule-like", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-198933); (R-RNO-202733)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transmembrane protein of the plasma membrane of leukocytes that control their migration and activation through interaction with CXADR, a plasma membrane receptor found on adjacent epithelial and endothelial cells. The interaction between both receptors mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair. It also controls the transmigration of leukocytes within epithelial and endothelial tissues through adhesive interactions with epithelial and endothelial CXADR., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005178 integrin binding;GO:0042803 protein homodimerization activity;GO:0050839 cell adhesion molecule binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005923 bicellular tight junction;GO:0016020 membrane", "go_biological_process": "GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0046629 gamma-delta T cell activation;GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing;GO:0030593 neutrophil chemotaxis;GO:0072672 neutrophil extravasation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A1C2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A1G2-1", "uniprot_id": "D4A1G2_RAT", "mass": 53431.0, "length": 482, "protein_name": "E2 ubiquitin-conjugating enzyme", "gene_name": "Ube2q2", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Ube2q2", "gene_names_refseq": "", "protein_names_uniprotkb": "E2 ubiquitin-conjugating enzyme; 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Altered expression of this protein and disruption of the molecular pathway it is involved in may contribute directly to or modify tumorigenesis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A1U8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A1W7-1", "uniprot_id": "D4A1W7_RAT", "mass": 150616.0, "length": 1325, "protein_name": "Nephrocystin-3", "gene_name": "Nphp3", "organism": "Rat", "refseq_name": "nephrocystin-3", "refseq_ac": "NP_001178811", "gene_names_uniprotkb": "Nphp3", "gene_names_refseq": "Nphp3; 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Pramel1", "gene_names_refseq": "Pramef27; Pramel1", "protein_names_uniprotkb": "PRAME family member 27", "protein_names_refseq": "PRAME family member 18-like; PRAME family member 19-like; PRAME family member 27; preferentially expressed antigen in melanoma-like 1", "tax_id": 10116, "disease": "", "pathway": " (rno:691051)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:1990756 ubiquitin-like ligase-substrate adaptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0001669 acrosomal vesicle;GO:0031462 Cul2-RING ubiquitin ligase complex", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0043066 negative regulation of apoptotic process;GO:0045892 negative regulation of DNA-templated transcription;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045596 negative regulation of cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A203-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A228-1", "uniprot_id": "D4A228_RAT", "mass": 162101.0, "length": 1438, "protein_name": "Myomesin-3", "gene_name": "Myom3", "organism": "Rat", "refseq_name": "myomesin-3 isoform 1", "refseq_ac": "NP_001101457", "gene_names_uniprotkb": "Myom3", "gene_names_refseq": "Myom3", "protein_names_uniprotkb": "Myomesin-3; Myomesin family member 3", "protein_names_refseq": "myomesin family, member 3; myomesin-3 isoform 1", "tax_id": 10116, "disease": "", "pathway": " (rno:313625)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May link the intermediate filament cytoskeleton to the M-disk of the myofibrils in striated muscle., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity;GO:0008307 structural constituent of muscle", "go_cellular_component": "GO:0031430 M band", "go_biological_process": "GO:0045214 sarcomere organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A228-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A2H3-1", "uniprot_id": "D4A2H3_RAT", "mass": 35195.0, "length": 309, "protein_name": "Olfactory receptor", "gene_name": "Or5h17b", "organism": "Rat", "refseq_name": "olfactory receptor Olr1555", "refseq_ac": "NP_001000726", "gene_names_uniprotkb": "Or5h17b", "gene_names_refseq": "Olr1555; Or5h17b", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1555; olfactory receptor Olr1555; olfactory receptor gene Olr1555", "tax_id": 10116, "disease": "", "pathway": " (rno:404980)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 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"glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0032483 regulation of Rab protein signal transduction;GO:0008333 endosome to lysosome transport;GO:0030163 protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "D4A2H4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A306-1", "uniprot_id": "D4A306_RAT", "mass": 70575.0, "length": 635, "protein_name": "RING finger protein 207", "gene_name": "Rnf207", "organism": "Rat", "refseq_name": "ring finger protein 207 isoform 1", "refseq_ac": "NP_001418228", "gene_names_uniprotkb": "Rnf207", "gene_names_refseq": "Rnf207", "protein_names_uniprotkb": "RING finger protein 207", "protein_names_refseq": "ring finger protein 207 isoform 1", "tax_id": 10116, "disease": "", "pathway": " (rno:691246)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in cardiac repolarization possibly by stabilizing membrane expression of the potassium channel KCNH2/HERG, or by assisting its synthesis, folding or export from the endoplasmic reticulum, in a heat shock protein-dependent manner., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, 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"Structure-selective DNA endonuclease that specifically cleaves branched DNA. Processes chromatin bridges during cytokinesis by cleaving DNA, both priming TREX1-mediated resolution and directly resolving bridges. Proper processing of chromatin bridges prevents their breakage during cytokinesis, thereby reducing DNA damage, micronuclei formation, and the activation of immune responses such as the cGAS-STING pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0030145 manganese ion binding;GO:0004519 endonuclease activity;GO:0004520 DNA endonuclease activity;GO:0050897 cobalt ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0030496 midbody", "go_biological_process": "GO:0000712 resolution of meiotic recombination intermediates;GO:0006974 DNA damage response;GO:0000724 double-strand break repair via homologous recombination;GO:0006611 protein export from nucleus;GO:0045950 negative regulation of mitotic recombination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A332-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A340-1", "uniprot_id": "D4A340_RAT", "mass": 46088.0, "length": 408, "protein_name": "AADACL4 family member 3 like 1", "gene_name": "Aadacl4fm3l1", "organism": "Rat", "refseq_name": "arylacetamide deacetylase-like 4", "refseq_ac": "XP_001077182", "gene_names_uniprotkb": "Aadacl4fm3l1; AAdacl4fm3l1; LOC691196", "gene_names_refseq": "AAdacl4fm3l1", "protein_names_uniprotkb": "AADACL4 family member 3 like 1", "protein_names_refseq": "arylacetamide deacetylase-like 4", "tax_id": 10116, "disease": "", "pathway": " (rno:691196)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0052689 carboxylic ester hydrolase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A340-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A3H7-1", "uniprot_id": "D4A3H7_RAT", "mass": 34900.0, "length": 312, "protein_name": "Olfactory receptor family 14 subfamily C member 39", "gene_name": "Or14c39", "organism": "Rat", "refseq_name": "olfactory receptor Olr34", "refseq_ac": "NP_001000689", "gene_names_uniprotkb": "Or14c39", "gene_names_refseq": "Olr34; 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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Or52h1; ratchr1-162109360-162108410_ORF", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 149; olfactory receptor Olr149; olfactory receptor gene Olr149", "tax_id": 10116, "disease": "", "pathway": " (rno:293289)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A3P2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A3S7-1", "uniprot_id": "D4A3S7_RAT", "mass": 72229.0, "length": 665, "protein_name": "Unk like zinc finger", "gene_name": "Unkl", "organism": "Rat", "refseq_name": "putative E3 ubiquitin-protein ligase UNKL isoform X3", "refseq_ac": "XP_017453092", "gene_names_uniprotkb": "Unkl", "gene_names_refseq": "Unkl", "protein_names_uniprotkb": "Unk like zinc finger", "protein_names_refseq": "putative E3 ubiquitin-protein ligase UNKL isoform X3", "tax_id": 10116, "disease": "", "pathway": " (rno:302987); 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zinc finger FYVE domain-containing protein 1; zinc finger, FYVE domain containing 1", "tax_id": 10116, "disease": "", "pathway": " (rno:299188)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008270 zinc ion binding;GO:0043325 phosphatidylinositol-3,4-bisphosphate binding;GO:0005545 1-phosphatidylinositol binding;GO:0032266 phosphatidylinositol-3-phosphate binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005811 lipid droplet;GO:0016020 membrane", "go_biological_process": "GO:0044829 host-mediated activation of viral genome replication;GO:0016236 macroautophagy;GO:0009267 cellular response to starvation;GO:0140042 lipid droplet formation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A3T4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A3U8-1", "uniprot_id": "D4A3U8_RAT", "mass": 101385.0, "length": 888, "protein_name": "Transmembrane channel-like protein", "gene_name": "Tmc2", "organism": "Rat", "refseq_name": "transmembrane channel-like protein 2", "refseq_ac": "NP_001099980", "gene_names_uniprotkb": "Tmc2", "gene_names_refseq": "Tmc2", "protein_names_uniprotkb": "Transmembrane channel-like protein", "protein_names_refseq": "transmembrane channel-like gene family 2; 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Or11h23b", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1622; olfactory receptor Olr1622; olfactory receptor gene Olr1622", "tax_id": 10116, "disease": "", "pathway": " (rno:405127)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A3V1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A482-1", "uniprot_id": "D4A482_RAT", "mass": 52701.0, "length": 494, "protein_name": "Sphingosine-1-phosphate transporter MFSD2B", "gene_name": "Mfsd2b", "organism": "Rat", "refseq_name": "sphingosine-1-phosphate transporter MFSD2B isoform X2", "refseq_ac": "XP_002729661", "gene_names_uniprotkb": "Mfsd2b", "gene_names_refseq": "Mfsd2b", "protein_names_uniprotkb": "Sphingosine-1-phosphate transporter MFSD2B; Major facilitator superfamily domain-containing protein 2B", "protein_names_refseq": "sphingosine-1-phosphate transporter MFSD2B isoform X2", "tax_id": 10116, "disease": "", "pathway": " (rno:500624); (R-RNO-1660661)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Lipid transporter that specifically mediates export of sphingosine-1-phosphate in red blood cells and platelets. Sphingosine-1-phosphate is a signaling sphingolipid and its export from red blood cells into in the plasma is required for red blood cell morphology. Sphingosine-1-phosphate export from platelets is required for platelet aggregation and thrombus formation. Mediates the export of different sphingosine-1-phosphate (S1P) species, including S1P(d18:0) (sphinganine 1-phosphate), S1P (d18:1) (sphing-4-enine 1-phosphate) and S1P (d18:2) (sphinga-4E,14Z-dienine-1-phosphate). Release of sphingosine-1-phosphate is facilitated by a proton gradient. In contrast, cations, such as sodium, are not required to drive sphingosine-1-phosphate transport. In addition to export, also able to mediate S1P import. Does not transport lysophosphatidylcholine (LPC)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015293 symporter activity;GO:0046624 sphingolipid transporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0003376 sphingosine-1-phosphate receptor signaling pathway;GO:0006869 lipid transport;GO:0055085 transmembrane transport;GO:0008643 carbohydrate transport;GO:1901731 positive regulation of platelet aggregation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A482-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A4A8-1", "uniprot_id": "D4A4A8_RAT", "mass": 118799.0, "length": 1077, "protein_name": "Inversin", "gene_name": "Invs", "organism": "Rat", "refseq_name": "inversin isoform X1", "refseq_ac": "XP_038965783", "gene_names_uniprotkb": "Invs", "gene_names_refseq": "Invs; RGD1563359", "protein_names_uniprotkb": "Inversin", "protein_names_refseq": "inversin isoform X1", "tax_id": 10116, "disease": "ciliopathy (Disease Ontology:DOID:0060340); nephronophthisis 2 (Disease Ontology:DOID:0111113); hypertension (Disease Ontology:DOID:10763); tetralogy of Fallot (Disease Ontology:DOID:6419)", "pathway": " (rno:313228)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for normal renal development and establishment of left-right axis. Probably acts as a molecular switch between different Wnt signaling pathways. Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled (DVL1) for degradation by the ubiquitin-proteasome. This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling. Involved in the organization of apical junctions in kidney cells together with NPHP1, NPHP4 and RPGRIP1L/NPHP8. Does not seem to be strictly required for ciliogenesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005929 cilium;GO:0097546 ciliary base;GO:0097543 ciliary inversin compartment", "go_biological_process": "GO:0060971 embryonic heart tube left/right pattern formation;GO:0006468 protein phosphorylation;GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0001822 kidney development;GO:0009791 post-embryonic development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A4A8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A4C7-1", "uniprot_id": "D4A4C7_RAT", "mass": 25284.0, "length": 232, "protein_name": "Membrane spanning 4-domains A3", "gene_name": "Ms4a3", "organism": "Rat", "refseq_name": "membrane-spanning 4-domains subfamily A member 3", "refseq_ac": "NP_001413982", "gene_names_uniprotkb": "Ms4a3", "gene_names_refseq": "Ms4a3", "protein_names_uniprotkb": "Membrane spanning 4-domains A3", "protein_names_refseq": "membrane-spanning 4-domains subfamily A member 3; membrane-spanning 4-domains, subfamily A, member 3", "tax_id": 10116, "disease": "", "pathway": " (rno:293753); (R-RNO-6798695)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A4C7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A4P8-1", "uniprot_id": "D4A4P8_RAT", "mass": 67556.0, "length": 614, "protein_name": "Protein tweety homolog", "gene_name": "Ttyh2", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Ttyh2", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein tweety homolog", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-2672351)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Probable chloride channel., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0072320 volume-sensitive chloride channel activity;GO:0005509 calcium ion binding;GO:0005229 intracellularly calcium-gated chloride channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0034707 chloride channel complex", "go_biological_process": "GO:0015813 L-glutamate transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A4P8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A4Y3-1", "uniprot_id": "D4A4Y3_RAT", "mass": 32728.0, "length": 298, "protein_name": "Membrane spanning 4-domains A1", "gene_name": "Ms4a1", "organism": "Rat", "refseq_name": "B-lymphocyte antigen CD20", "refseq_ac": "NP_001386381", "gene_names_uniprotkb": "Ms4a1", "gene_names_refseq": "Cd20; Ms4a1", "protein_names_uniprotkb": "Membrane spanning 4-domains A1", "protein_names_refseq": "B-lymphocyte antigen CD20; membrane-spanning 4-domains, subfamily A, member 1", "tax_id": 10116, "disease": "common variable immunodeficiency 5 (Disease Ontology:DOID:0081148); glomerulonephritis (Disease Ontology:DOID:2921)", "pathway": " (rno:309217)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0005154 epidermal growth factor receptor binding;GO:0019865 immunoglobulin binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0044853 plasma membrane raft;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0051262 protein tetramerization;GO:0042113 B cell activation;GO:0009617 response to bacterium;GO:0050853 B cell receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A4Y3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A542-1", "uniprot_id": "D4A542_RAT", "mass": 93972.0, "length": 836, "protein_name": "G protein-coupled receptor associated sorting protein 2", "gene_name": "Gprasp2", "organism": "Rat", "refseq_name": "G-protein coupled receptor-associated sorting protein 2", "refseq_ac": "NP_001388086", "gene_names_uniprotkb": "Gprasp2", "gene_names_refseq": "Gprasp2; RGD1561019", "protein_names_uniprotkb": "G protein-coupled receptor associated sorting protein 2", "protein_names_refseq": "G-protein coupled receptor-associated sorting protein 2", "tax_id": 10116, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041); X-linked deafness 7 (Disease Ontology:DOID:0111738); intellectual disability (Disease Ontology:DOID:1059)", "pathway": " (rno:317405)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001540 amyloid-beta binding;GO:0001664 G protein-coupled receptor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0061484 hematopoietic stem cell homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A542-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A553-1", "uniprot_id": "D4A553_RAT", "mass": 38301.0, "length": 339, "protein_name": "Centrosomal AT-AC splicing factor", "gene_name": "Cenatac", "organism": "Rat", "refseq_name": "centrosomal AT-AC splicing factor isoform X1", "refseq_ac": "XP_008764400", "gene_names_uniprotkb": "Cenatac; Ccdc84", "gene_names_refseq": "Ccdc84; Cenatac", "protein_names_uniprotkb": "Centrosomal AT-AC splicing factor", "protein_names_refseq": "centrosomal AT-AC splicing factor isoform X1", "tax_id": 10116, "disease": "mosaic variegated aneuploidy syndrome 4 (Disease Ontology:DOID:0060981)", "pathway": " (rno:689046)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005813 centrosome;GO:0071016 U12-type precatalytic spliceosome", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0051304 chromosome separation;GO:0042176 regulation of protein catabolic process;GO:0010826 negative regulation of centrosome duplication", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A553-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A599-1", "uniprot_id": "D4A599_RAT", "mass": 509890.0, "length": 4459, "protein_name": "Dynein axonemal heavy chain 17", "gene_name": "Dnah17", "organism": "Rat", "refseq_name": "dynein axonemal heavy chain 17", "refseq_ac": "XP_038943440", "gene_names_uniprotkb": "Dnah17", "gene_names_refseq": "Dnah17", "protein_names_uniprotkb": "Dynein axonemal heavy chain 17; Axonemal beta dynein heavy chain 17; Ciliary dynein heavy chain 17", "protein_names_refseq": "dynein axonemal heavy chain 17", "tax_id": 10116, "disease": "spermatogenic failure 39 (Disease Ontology:DOID:0111926); sensorineural hearing loss (Disease Ontology:DOID:10003)", "pathway": " (rno:287845)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Force generating protein component of the outer dynein arms (ODAs) in the sperm flagellum. Produces force towards the minus ends of microtubules. Key component of dynein, a family of motor proteins essential for movement along microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of cilia. Plays a major role in sperm motility, implicated in sperm flagellar assembly and beating., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0008569 minus-end-directed microtubule motor activity;GO:0051959 dynein light intermediate chain binding;GO:0045505 dynein intermediate chain binding", "go_cellular_component": "GO:0097229 sperm end piece;GO:0005874 microtubule;GO:0036126 sperm flagellum;GO:0005930 axoneme;GO:0097228 sperm principal piece", "go_biological_process": "GO:0060294 cilium movement involved in cell motility;GO:0036158 outer dynein arm assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A599-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K583-1", "uniprot_id": "A0A0G2K583_RAT", "mass": 31089.0, "length": 283, "protein_name": "S-methyl-5'-thioadenosine phosphorylase", "gene_name": "Mtap", "organism": "Rat", "refseq_name": "S-methyl-5'-thioadenosine phosphorylase", "refseq_ac": "NP_001380978", "gene_names_uniprotkb": "Mtap; MTAP", "gene_names_refseq": "Cc1-6; Mtap", "protein_names_uniprotkb": "S-methyl-5'-thioadenosine phosphorylase; 2.4.2.28; 5'-methylthioadenosine phosphorylase; MTA phosphorylase; MTAPase; MTAP", "protein_names_refseq": "5'-methylthioadenosine phosphorylase; S-methyl-5'-thioadenosine phosphorylase", "tax_id": 10116, "disease": "biliary tract benign neoplasm (Disease Ontology:DOID:0050625); diaphyseal medullary stenosis with malignant fibrous histiocytoma (Disease Ontology:DOID:0080664); pancreatic cancer (Disease Ontology:DOID:1793); common bile duct neoplasm (Disease Ontology:DOID:4608)", "pathway": " (rno:298227); (R-RNO-1237112)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "27748820", "class_list": "", "function": "Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates., [UniProtKB, HAMAP, UniProtKB]; These protein profiles, and their interacting protein network, may facilitate the elucidation of the molecular mechanisms underlying the antiinflammatory effects of CC16., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.2.28;3.5.4.4;2.4.2.1", "go_molecular_function": "GO:0017061 S-methyl-5-thioadenosine phosphorylase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0006166 purine ribonucleoside salvage;GO:0032259 methylation;GO:0019509 L-methionine salvage from methylthioadenosine;GO:0033574 response to testosterone", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K583-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A140TAJ4-1", "uniprot_id": "A0A140TAJ4_RAT", "mass": 40709.0, "length": 361, "protein_name": "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5, pseudogene 1", "gene_name": "Hsd3b5-ps1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Hsd3b5-ps1", "gene_names_refseq": "", "protein_names_uniprotkb": "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5, pseudogene 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); hypospadias (Disease Ontology:DOID:10892); polycystic ovary syndrome (Disease Ontology:DOID:11612)", "pathway": " (R-RNO-193048); (R-RNO-193993); (R-RNO-194002)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003854 3-beta-hydroxy-Delta5-steroid dehydrogenase (NAD+) activity;GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor", "go_cellular_component": "GO:0005737 cytoplasm;GO:0031966 mitochondrial membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006694 steroid biosynthetic process;GO:0008207 C21-steroid hormone metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140TAJ4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K418-1", "uniprot_id": "A0A0G2K418_RAT", "mass": 108218.0, "length": 978, "protein_name": "Storkhead box 1", "gene_name": "Stox1", "organism": "Rat", "refseq_name": "storkhead-box protein 1", "refseq_ac": "NP_001178649", "gene_names_uniprotkb": "Stox1", "gene_names_refseq": "RGD1310622; Stox1", "protein_names_uniprotkb": "Storkhead box 1", "protein_names_refseq": "storkhead-box protein 1", "tax_id": 10116, "disease": "pre-eclampsia (Disease Ontology:DOID:10591); Alzheimer's disease (Disease Ontology:DOID:10652)", "pathway": " (rno:294388)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "31207359", "class_list": "", "function": "Stox1 induced proliferation of pulmonary artery smooth muscle cells, and the effect is, at least in part, mediated through AKT signaling pathway., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005829 cytosol", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0010628 positive regulation of gene expression;GO:0010629 negative regulation of gene expression;GO:0010800 positive regulation of peptidyl-threonine phosphorylation;GO:0010971 positive regulation of G2/M transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K418-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZTJ0-1", "uniprot_id": "D3ZTJ0_RAT", "mass": 39655.0, "length": 350, "protein_name": "Protein XRP2", "gene_name": "Rp2", "organism": "Rat", "refseq_name": "protein XRP2", "refseq_ac": "NP_001102482", "gene_names_uniprotkb": "Rp2", "gene_names_refseq": "RGD1565124; Rp2h; Rp2", "protein_names_uniprotkb": "Protein XRP2", "protein_names_refseq": "RP2, ARL3 GTPase activating protein; protein XRP2; retinitis pigmentosa 2 (X-linked recessive); retinitis pigmentosa 2 homolog", "tax_id": 10116, "disease": "retinitis pigmentosa 2 (Disease Ontology:DOID:0110415); retinitis pigmentosa (Disease Ontology:DOID:10584)", "pathway": " (rno:367714); (R-RNO-5624138)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Acts as a GTPase-activating protein (GAP) involved in trafficking between the Golgi and the ciliary membrane. Involved in localization of proteins, such as NPHP3, to the cilium membrane by inducing hydrolysis of GTP ARL3, leading to the release of UNC119 (or UNC119B). Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. Acts as a guanine nucleotide dissociation inhibitor towards ADP-ribosylation factor-like proteins., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005096 GTPase activator activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0005929 cilium;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0006892 post-Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZTJ0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A0F7-1", "uniprot_id": "D4A0F7_RAT", "mass": 33966.0, "length": 292, "protein_name": "Defective in cullin neddylation 1 domain containing 4", "gene_name": "Dcun1d4", "organism": "Rat", "refseq_name": "DCN1-like protein 4 isoform 1", "refseq_ac": "NP_001101829", "gene_names_uniprotkb": "Dcun1d4", "gene_names_refseq": "Dcun1d4; RGD1310422", "protein_names_uniprotkb": "Defective in cullin neddylation 1 domain containing 4", "protein_names_refseq": "DCN1, defective in cullin neddylation 1, domain containing 4; DCN1-like protein 4 isoform 1; DCN1-like protein 4", "tax_id": 10116, "disease": "", "pathway": " (rno:360928); (R-RNO-8951664)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0032182 ubiquitin-like protein binding;GO:0097602 cullin family protein binding;GO:0031624 ubiquitin conjugating enzyme binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000151 ubiquitin ligase complex", "go_biological_process": "GO:0045116 protein neddylation;GO:2000436 positive regulation of protein neddylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A0F7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K2U6-1", "uniprot_id": "A0A0G2K2U6_RAT", "mass": 76225.0, "length": 667, "protein_name": "G-protein coupled receptors family 3 profile domain-containing protein", "gene_name": "Vom2r40", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Vom2r40; LOC134485148; Vom2r41", "gene_names_refseq": "", "protein_names_uniprotkb": "G-protein coupled receptors family 3 profile domain-containing protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K2U6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K4M5-1", "uniprot_id": "A0A0G2K4M5_RAT", "mass": 62420.0, "length": 552, "protein_name": "Zinc finger protein 94", "gene_name": "Zfp61; Zfp94", "organism": "Rat", "refseq_name": "zinc finger protein 61", "refseq_ac": "NP_001017512", "gene_names_uniprotkb": "Zfp61; Zfp94; Zfp61; Zfp94", "gene_names_refseq": "Zfp61", "protein_names_uniprotkb": "Zinc finger protein 94", "protein_names_refseq": "zinc finger protein 61", "tax_id": 10116, "disease": "", "pathway": " (rno:499094); (rno:499095)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005634 nucleus", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K4M5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K5L3-1", "uniprot_id": "A0A0G2K5L3_RAT", "mass": 65185.0, "length": 566, "protein_name": "Serine/threonine-protein kinase RIO1", "gene_name": "Riok1", "organism": "Rat", "refseq_name": "serine/threonine-protein kinase RIO1", "refseq_ac": "NP_001093981", "gene_names_uniprotkb": "Riok1", "gene_names_refseq": "Riok1", "protein_names_uniprotkb": "Serine/threonine-protein kinase RIO1; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase RIO1", "tax_id": 10116, "disease": "colon cancer (Disease Ontology:DOID:219)", "pathway": " (rno:291061); (R-RNO-6791226)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in processing of 18S-E pre-rRNA to the mature 18S rRNA. Required for the recycling of NOB1 and PNO1 from the late 40S precursor. The association with the very late 40S subunit intermediate may involve a translation-like checkpoint point cycle preceeding the binding to the 60S ribosomal subunit. Despite the protein kinase domain is proposed to act predominantly as an ATPase. The catalytic activity regulates its dynamic association with the 40S subunit. In addition to its role in ribosomal biogenesis acts as an adapter protein by recruiting NCL/nucleolin the to PRMT5 complex for its symmetrical methylation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.6.2.3;2.7.11.1;3.6.4.13;2.7.12.1;3.6.4.12;2.7.1.153;2.7.1.137;3.6.1.5;2.7.11.24;2.7.11.25;2.7.11.22;2.7.11.23;3.6.4.10;3.6.4.-;2.7.4.6;2.3.2.27;2.7.1.154;2.7.11.38;2.7.11.17;2.7.11.21;2.7.12.2;5.6.2.4;2.7.1.40;2.7.11.12;3.6.5.-;2.7.11.26;5.6.2.-;2.7.11.34;3.1.-.-;2.7.10.2;2.7.1.150;2.7.11.13;2.7.7.7;2.7.7.49;3.1.13.1;4.2.99.18;4.1.1.32;7.6.2.2;7.6.2.3;7.6.2.-;5.6.1.6;7.2.2.-;3.6.1.15;3.6.4.6;3.1.3.1;3.9.1.1;2.7.11.19;6.1.1.12;2.7.2.3;2.7.11.11;3.6.1.-;2.7.11.31;3.1.3.16;2.7.11.4;2.3.1.48;3.1.11.-;2.7.13.3;2.7.4.18;3.1.24.-;2.7.4.3;3.4.19.12;2.7.11.39;3.1.4.-;3.4.24.-;3.6.-.-;2.4.99.18;3.4.21.53;5.6.2.5;2.7.11.10", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0034709 methylosome;GO:0030688 preribosome, small subunit precursor;GO:0034708 methyltransferase complex", "go_biological_process": "GO:2000234 positive regulation of rRNA processing;GO:0042274 ribosomal small subunit biogenesis;GO:0030490 maturation of SSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K5L3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A1B0GWT7-1", "uniprot_id": "A0A1B0GWT7_RAT", "mass": 26605.0, "length": 253, "protein_name": "Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2", "gene_name": "Lamtor2", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Lamtor2", "gene_names_refseq": "", "protein_names_uniprotkb": "Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-1632852); (R-RNO-165159); (R-RNO-166208); (R-RNO-380972); (R-RNO-5628897); (R-RNO-5674135); (R-RNO-6798695); (R-RNO-8943724); (R-RNO-9639288)", "pathway_count": 9, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator plays a dual role for the small GTPases Rag (RagA/RRAGA, RagB/RRAGB, RagC/RRAGC and/or RagD/RRAGD): it (1) acts as a guanine nucleotide exchange factor (GEF), activating the small GTPases Rag and (2) mediates recruitment of Rag GTPases to the lysosome membrane. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0005770 late endosome;GO:0071986 Ragulator complex;GO:1990877 FNIP-folliculin RagC/D GAP", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0043410 positive regulation of MAPK cascade;GO:0001558 regulation of cell growth;GO:0032008 positive regulation of TOR signaling;GO:0008104 intracellular protein localization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1B0GWT7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K1T5-1", "uniprot_id": "A0A0G2K1T5_RAT", "mass": 58037.0, "length": 531, "protein_name": "Eyes absent homolog", "gene_name": "Eya2", "organism": "Rat", "refseq_name": "eyes absent homolog 2 isoform 1", "refseq_ac": "NP_001417067", "gene_names_uniprotkb": "Eya2", "gene_names_refseq": "Eya2", "protein_names_uniprotkb": "Eyes absent homolog; 3.1.3.48", "protein_names_refseq": "Drosophila-type eyes absent 2-like protein; eyes absent 2 homolog; eyes absent homolog 2 isoform 1; eyes absent homolog 2", "tax_id": 10116, "disease": "branchiootorenal syndrome (Disease Ontology:DOID:14702); eye disease (Disease Ontology:DOID:5614)", "pathway": " (R-RNO-5693565)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.3.48;2.7.10.1;3.1.3.16;3.1.3.2;2.7.11.1;3.1.3.21;3.1.3.18;3.1.3.67;3.1.3.-;3.1.3.27;3.1.3.5;2.3.1.48;2.3.1.-;3.6.-.-;3.1.-.-", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004725 protein tyrosine phosphatase activity;GO:0140793 histone H2AXY142 phosphatase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0014706 striated muscle tissue development;GO:0006281 DNA repair;GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0045739 positive regulation of DNA repair", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K1T5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P10252-1", "uniprot_id": "CD48_RAT", "mass": 27680.0, "length": 240, "protein_name": "CD48 antigen", "gene_name": "Cd48", "organism": "Rat", "refseq_name": "CD48 antigen precursor", "refseq_ac": "NP_620803", "gene_names_uniprotkb": "Cd48; Bcm-1", "gene_names_refseq": "Cd48; SLAMF2", "protein_names_uniprotkb": "CD48 antigen; BCM1 surface antigen; BLAST-1; MRC OX-45 surface antigen; SLAM family member 2; SLAMF2; Signaling lymphocytic activation molecule 2", "protein_names_refseq": "BCM1 surface antigen; BLAST-1; CD48 antigen precursor; CD48 antigen; MRC OX-45 surface antigen; SLAM family member 2; signaling lymphocytic activation molecule 2", "tax_id": 10116, "disease": "", "pathway": " (rno:245962); (R-RNO-202733)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "10207177;16803907;29393594;3181129", "class_list": "", "function": "CD48 is a CD2 and CD244 (2B4)-binding protein, [RefSeq, PubMed]; Glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein that interacts via its N-terminal immunoglobulin domain with cell surface receptors including 2B4/CD244 or CD2 to regulate immune cell function and activation. Participates in T-cell signaling transduction by associating with CD2 and efficiently bringing the Src family protein kinase LCK and LAT to the TCR/CD3 complex. In turn, promotes LCK phosphorylation and subsequent activation. Induces the phosphorylation of the cytoplasmic immunoreceptortyrosine switch motifs (ITSMs) of CD244 initiating a series of signaling events that leads to the generation of the immunological synapse and the directed release of cytolytic granules containing perforin and granzymes by T-lymphocytes and NK-cells., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 4, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 1, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 5, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 5, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 13, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 1, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 34, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0048018 receptor ligand activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0045121 membrane raft;GO:0009897 external side of plasma membrane;GO:0032991 protein-containing complex;GO:0005886 plasma membrane", "go_biological_process": "GO:0006955 immune response;GO:0007165 signal transduction;GO:0042110 T cell activation;GO:0030101 natural killer cell activation;GO:0045576 mast cell activation", "synthesized_glycan_count": 0, "hit_score": 4.4, "record_id": "P10252-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P21263-1", "uniprot_id": "NEST_RAT", "mass": 208797.0, "length": 1893, "protein_name": "Nestin", "gene_name": "Nes", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Nes", "gene_names_refseq": "", "protein_names_uniprotkb": "Nestin", "protein_names_refseq": "", "tax_id": 10116, "disease": "brain ischemia (Disease Ontology:DOID:2316); nephrosis (Disease Ontology:DOID:2527); acute kidney failure (Disease Ontology:DOID:3021); brain infarction (Disease Ontology:DOID:3454)", "pathway": "", "pathway_count": 0, "publication_count": 6, "publication_id_list": "11278541;12686602;15966898;1689217;20510364;22673903", "class_list": "", "function": "Required for brain and eye development (By similarity). Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells., [UniProtKB, PubMed, PubMed]; Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 27, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8CJ14", "ec_number_list": "", "go_molecular_function": "GO:0019215 intermediate filament binding;GO:0031730 CCR5 chemokine receptor binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005882 intermediate filament;GO:0045111 intermediate filament cytoskeleton", "go_biological_process": "GO:0007399 nervous system development;GO:0000086 G2/M transition of mitotic cell cycle;GO:0031667 response to nutrient levels;GO:0043086 negative regulation of catalytic activity;GO:0043524 negative regulation of neuron apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P21263-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K2P5-1", "uniprot_id": "ZO1_RAT", "mass": 197148.0, "length": 1765, "protein_name": "Tight junction protein ZO-1", "gene_name": "Tjp1", "organism": "Rat", "refseq_name": "tight junction protein ZO-1 isoform 1", "refseq_ac": "NP_001424421", "gene_names_uniprotkb": "Tjp1", "gene_names_refseq": "Tjp1; ZO-1", "protein_names_uniprotkb": "Tight junction protein ZO-1; Tight junction protein 1; Zona occludens protein 1; Zonula occludens protein 1", "protein_names_refseq": "tight junction protein ZO-1 isoform 1; tight junction protein ZO-1; zona occludens 1; zona occludens protein 1; zonula occludens protein 1", "tax_id": 10116, "disease": "metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); uveitis (Disease Ontology:DOID:13141); cholestasis (Disease Ontology:DOID:13580); peptic esophagitis (Disease Ontology:DOID:13976); brain ischemia (Disease Ontology:DOID:2316); bile duct cancer (Disease Ontology:DOID:4606); gallbladder carcinoma (Disease Ontology:DOID:4948); perinatal necrotizing enterocolitis (Disease Ontology:DOID:8677); brain disease (Disease Ontology:DOID:936)", "pathway": " (R-RNO-191650); (R-RNO-2028269); (R-RNO-351906)", "pathway_count": 3, "publication_count": 8, "publication_id_list": "16641100;22673903;32716860;32807750;33343804;34552687;3528172;9707407", "class_list": "", "function": "Lactobacillus casei LC01 Regulates Intestinal Epithelial Permeability through miR-144 Targeting of OCLN and ZO1., [RefSeq, PubMed]; Neonatal Hyperoxia Downregulates Claudin-4, Occludin, and ZO-1 Expression in Rat Kidney Accompanied by Impaired Proximal Tubular Development. Publication Status: Online-Only, [RefSeq, PubMed]; The magnitude of physical exercise-induced hyperthermia is associated with changes in the intestinal permeability and expression of tight junction genes in rats., [RefSeq, PubMed]; TjpP1, Tjp2, and Tjp3 are closely related scaffolding proteins that link tight junction (TJ) transmembrane proteins such as claudins, junctional adhesion molecules, and occludin to the actin cytoskeleton (PubMed:9707407). The tight junction acts to limit movement of substances through the paracellular space and as a boundary between the compositionally distinct apical and basolateral plasma membrane domains of epithelial and endothelial cells. Necessary for lumenogenesis, and particularly efficient epithelial polarization and barrier formation (By similarity). Plays a role in the regulation of cell migration by targeting Cdc42bpb to the leading edge of migrating cells (By similarity). Plays an important role in podosome formation and associated function, thus regulating cell adhesion and matrix remodeling (By similarity). With Tjp2 and Tjp3, participates in the junctional retention and stability of the transcription factor Dbpa, but is not involved in its shuttling to the nucleus (By similarity). May play a role in mediating cell morphology changes during ameloblast differentiation via its role in tight junctions (By similarity)., [UniProtKB, UniProtKB, PubMed, UniProtKB, UniProtKB]; VIP Stabilizes the Cytoskeleton of Schlemm's Canal Endothelia via Reducing Caspase-3 Mediated ZO-1 Endolysosomal Degradation. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 46, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0071253 connexin binding;GO:0005524 ATP binding;GO:0019904 protein domain specific binding;GO:0044325 transmembrane transporter binding;GO:0050839 cell adhesion molecule binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005911 cell-cell junction;GO:0005912 adherens junction", "go_biological_process": "GO:1903672 positive regulation of sprouting angiogenesis;GO:0150105 protein localization to cell-cell junction;GO:0008284 positive regulation of cell population proliferation;GO:0030335 positive regulation of cell migration;GO:0032496 response to lipopolysaccharide", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A0G2K2P5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "M0RBL7-1", "uniprot_id": "M0RBL7_RAT", "mass": 101133.0, "length": 919, "protein_name": "TRPM8 channel associated factor 2C", "gene_name": "Tcaf2c", "organism": "Rat", "refseq_name": "TRPM8 channel associated factor 2C", "refseq_ac": "NP_001418920", "gene_names_uniprotkb": "Tcaf2c; Fam115c; LOC134486765", "gene_names_refseq": "Fam115c; Fam139a; Tcaf2c; Tcaf2", "protein_names_uniprotkb": "TRPM8 channel associated factor 2C", "protein_names_refseq": "TRPM8 channel associated factor 2C; family with sequence similarity 115, member C; family with sequence similarity 139, member A; protein FAM115C-like", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0044325 transmembrane transporter binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0090314 positive regulation of protein targeting to membrane;GO:0010360 negative regulation of anion channel activity", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0RBL7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LSB5-1", "uniprot_id": "F1LSB5_RAT", "mass": 153583.0, "length": 1450, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Lmtk3", "organism": "Rat", "refseq_name": "serine/threonine-protein kinase LMTK3 isoform X2", "refseq_ac": "XP_008757681", "gene_names_uniprotkb": "Lmtk3", "gene_names_refseq": "Lmtk3", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase LMTK3 isoform X2", "tax_id": 10116, "disease": "", "pathway": " (rno:691056)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.12.1;2.7.1.153;2.7.1.137;2.7.11.24;2.7.11.25;2.7.11.22;2.7.11.23;2.7.4.6;2.7.1.154;2.7.11.38;2.7.11.17;2.7.11.21;2.7.12.2;2.7.1.40;2.7.11.12;2.7.11.26;2.7.11.34;2.7.10.2;2.7.1.150;2.7.11.13;4.1.1.32;2.7.11.19;2.7.2.3;2.7.11.11;2.7.11.31;3.1.3.16;2.7.11.4;2.3.1.48;3.1.11.-;2.7.13.3;2.7.4.18;3.1.24.-;3.4.19.12;2.7.11.39;2.4.99.18;2.7.11.10", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004672 protein kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0030425 dendrite;GO:0012505 endomembrane system", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LSB5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LPD7-1", "uniprot_id": "F1LPD7_RAT", "mass": 179500.0, "length": 1609, "protein_name": "Thrombospondin type-1 domain-containing protein 7B", "gene_name": "Thsd7b", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Thsd7b", "gene_names_refseq": "", "protein_names_uniprotkb": "Thrombospondin type-1 domain-containing protein 7B", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:289007); (R-RNO-5173214)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "38843836", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0030036 actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "F1LPD7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LQJ7-1", "uniprot_id": "F1LQJ7_RAT", "mass": 73696.0, "length": 667, "protein_name": "Phosphoenolpyruvate carboxykinase [GTP], mitochondrial", "gene_name": "Pck2", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Pck2", "gene_names_refseq": "", "protein_names_uniprotkb": "Phosphoenolpyruvate carboxykinase [GTP], mitochondrial; 4.1.1.32; Serine/threonine-protein kinase PCK2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-70263)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mitochondrial phosphoenolpyruvate carboxykinase that catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. Can play an active role in glyceroneogenesis and gluconeogenesis. Also acts as a serine/threonine-protein kinase: phosphorylates and activates ACSL4, thereby promoting ferroptosis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.12.1;2.7.11.24;2.7.11.25;2.7.11.22;2.7.11.23;2.7.4.6;2.7.11.38;2.7.11.17;2.7.11.21;2.7.12.2;2.7.1.40;2.7.11.12;2.7.11.26;2.7.11.34;2.7.10.2;2.7.11.13;4.1.1.32;2.7.11.-;2.7.11.19;2.7.11.11;2.7.11.31;3.1.3.16;3.1.11.-;2.7.13.3;2.7.4.18;3.1.24.-;3.4.19.12;2.7.11.39;2.4.99.18;2.7.11.10", "go_molecular_function": "GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0004613 phosphoenolpyruvate carboxykinase (GTP) activity;GO:0004674 protein serine/threonine kinase activity;GO:0030145 manganese ion binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006094 gluconeogenesis;GO:0042866 pyruvate biosynthetic process;GO:0046327 glycerol biosynthetic process from pyruvate;GO:0032024 positive regulation of insulin secretion;GO:0032496 response to lipopolysaccharide", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LQJ7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1M8L9-1", "uniprot_id": "F1M8L9_RAT", "mass": 139865.0, "length": 1256, "protein_name": "CRK SH3-binding GNRP", "gene_name": "Rapgef1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Rapgef1", "gene_names_refseq": "", "protein_names_uniprotkb": "CRK SH3-binding GNRP", "protein_names_refseq": "", "tax_id": 10116, "disease": "anti-basement membrane glomerulonephritis (Disease Ontology:DOID:4780); mesangial proliferative glomerulonephritis (Disease Ontology:DOID:4783)", "pathway": " (rno:63881); (R-RNO-170968); (R-RNO-186763); (R-RNO-8875555); (R-RNO-9013423); (R-RNO-9027284); (R-RNO-912631)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0048471 perinuclear region of cytoplasm;GO:0030670 phagocytic vesicle membrane", "go_biological_process": "GO:0007264 small GTPase-mediated signal transduction;GO:0046580 negative regulation of Ras protein signal transduction;GO:0061028 establishment of endothelial barrier;GO:0032486 Rap protein signal transduction;GO:0010976 positive regulation of neuron projection development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1M8L9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "M0RC54-1", "uniprot_id": "M0RC54_RAT", "mass": 327692.0, "length": 3039, "protein_name": "Biorientation of chromosomes in cell division 1-like 1", "gene_name": "Bod1l1", "organism": "Rat", "refseq_name": "biorientation of chromosomes in cell division protein 1-like 1 isoform X2", "refseq_ac": "XP_038948742", "gene_names_uniprotkb": "Bod1l1; 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tetratricopeptide repeat protein 16", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0RBH7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "M0R3T8-1", "uniprot_id": "M0R3T8_RAT", "mass": 191346.0, "length": 1675, "protein_name": "Ankyrin repeat domain containing 26", "gene_name": "Ankrd26", "organism": "Rat", "refseq_name": "ankyrin repeat domain-containing protein 26", "refseq_ac": "XP_232319", "gene_names_uniprotkb": "Ankrd26", "gene_names_refseq": "Ankrd26; RGD1310736", "protein_names_uniprotkb": "Ankyrin repeat domain containing 26", "protein_names_refseq": "ankyrin repeat domain containing 26; ankyrin repeat domain-containing protein 26; ankyrin repeat domain-containing protein 30A", "tax_id": 10116, "disease": "thrombocytopenia (Disease Ontology:DOID:1588); obesity (Disease Ontology:DOID:9970)", "pathway": " (rno:312667); (R-RNO-9696264); (R-RNO-9696270); (R-RNO-9696273)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005813 centrosome;GO:0015629 actin cytoskeleton", "go_biological_process": "GO:0046627 negative regulation of insulin receptor signaling pathway;GO:0046621 negative regulation of organ growth;GO:0019216 regulation of lipid metabolic process;GO:0019217 regulation of fatty acid metabolic process;GO:0042593 glucose homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R3T8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LRE5-1", "uniprot_id": "F1LRE5_RAT", "mass": 83068.0, "length": 736, "protein_name": "Oxysterol-binding protein", "gene_name": "Osbpl9", "organism": "Rat", "refseq_name": "oxysterol-binding protein-related protein 9 isoform X4", "refseq_ac": "XP_038965491", "gene_names_uniprotkb": "Osbpl9", "gene_names_refseq": "Osbpl9", "protein_names_uniprotkb": "Oxysterol-binding protein", "protein_names_refseq": "oxysterol-binding protein-related protein 9 isoform X4", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-192105)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Interacts with OSBPL11 to function as lipid transfer proteins. Together they form a heterodimer that localizes at the ER-trans-Golgi membrane contact sites, and exchanges phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L-serine, PS) for phosphatidylinositol-4-phosphate (1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate), PI(4)P) between the two organelles, a step that is critical for sphingomyelin synthesis in the Golgi complex., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008289 lipid binding;GO:0032934 sterol binding;GO:0160270 phosphatidylserine-phosphatidylinositol-4-phosphate exchange activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0016020 membrane;GO:0005765 lysosomal membrane;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0006869 lipid transport;GO:0006649 phospholipid transfer to membrane;GO:0055091 phospholipid homeostasis;GO:0097212 lysosomal membrane organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1LRE5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A8G5-1", "uniprot_id": "D4A8G5_RAT", "mass": 74753.0, "length": 685, "protein_name": "Transforming growth factor-beta-induced protein ig-h3", "gene_name": "Tgfbi", "organism": "Rat", "refseq_name": "transforming growth factor-beta-induced protein ig-h3 precursor", "refseq_ac": "NP_446254", "gene_names_uniprotkb": "Tgfbi", "gene_names_refseq": "BIGH3; Big-h3; Tgfbi", "protein_names_uniprotkb": "Transforming growth factor-beta-induced protein ig-h3", "protein_names_refseq": "transforming growth factor, beta induced, 68 kDa; transforming growth factor-beta-induced protein ig-h3 precursor; transforming growth factor-beta-induced protein ig-h3", "tax_id": 10116, "disease": "granular corneal dystrophy 2 (Disease Ontology:DOID:0060444); epithelial basement membrane dystrophy (Disease Ontology:DOID:0060447); Reis-Bucklers corneal dystrophy (Disease Ontology:DOID:0060453); Thiel-Behnke corneal dystrophy (Disease Ontology:DOID:0060455); granular corneal dystrophy 1 (Disease Ontology:DOID:0080530); corneal dystrophy (Disease Ontology:DOID:2566); kidney disease (Disease Ontology:DOID:557)", "pathway": " (rno:116487)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12911551;25740786;32312943", "class_list": "", "function": "Betaig-h3 enhances chondrogenesis via promoting mesenchymal condensation in rat Achilles tendon heterotopic ossification model., [RefSeq, PubMed]; Betaig-h3 may be important in development of diabetic nephropathy. Level of urinary betaig-h3 may be useful as early marker reflecting disease onset and progression., [RefSeq, PubMed]; Plays a role in cell adhesion. May play a role in cell-collagen interactions., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Studies reveal that growth hormone (GH)increases TGFBI expression in a mouse and rat models of diabetic nephropathy (DN) which correlate with clinical results, and suggest that this mechanism can explain the podocytes depletion in DN. Erratum:[J Cell Biochem. 2020 Feb;121(2):2047. PMID: 31852172], [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0005518 collagen binding;GO:0050839 cell adhesion molecule binding;GO:0050840 extracellular matrix binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0071944 cell periphery;GO:0031012 extracellular matrix;GO:0005604 basement membrane;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0007155 cell adhesion;GO:0030198 extracellular matrix organization;GO:0001525 angiogenesis;GO:0002062 chondrocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "D4A8G5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A709-1", "uniprot_id": "D4A709_RAT", "mass": 197084.0, "length": 1763, "protein_name": "Gamma-tubulin complex component 6", "gene_name": "Tubgcp6", "organism": "Rat", "refseq_name": "gamma-tubulin complex component 6", "refseq_ac": "NP_001102218", "gene_names_uniprotkb": "Tubgcp6", "gene_names_refseq": "Tubgcp6", "protein_names_uniprotkb": "Gamma-tubulin complex component 6", "protein_names_refseq": "gamma-tubulin complex component 6; tubulin, gamma complex associated protein 6", "tax_id": 10116, "disease": "microcephaly and chorioretinopathy 1 (Disease Ontology:DOID:0080105)", "pathway": " (rno:362980); (R-RNO-380270); (R-RNO-380320)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0043015 gamma-tubulin binding;GO:0008017 microtubule binding", "go_cellular_component": "GO:0000922 spindle pole;GO:0005813 centrosome;GO:0005874 microtubule;GO:0000930 gamma-tubulin complex;GO:0000931 gamma-tubulin ring complex", "go_biological_process": "GO:0007020 microtubule nucleation;GO:0000278 mitotic cell cycle;GO:0051225 spindle assembly;GO:0051321 meiotic cell cycle;GO:0031122 cytoplasmic microtubule organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A709-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A7U1-1", "uniprot_id": "D4A7U1_RAT", "mass": 70642.0, "length": 667, "protein_name": "Zyxin", "gene_name": "Zyx", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Zyx", "gene_names_refseq": "", "protein_names_uniprotkb": "Zyxin", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Adhesion plaque protein. Binds alpha-actinin and the CRP protein. Important for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0005925 focal adhesion;GO:0005912 adherens junction", "go_biological_process": "GO:0007229 integrin-mediated signaling pathway;GO:0007160 cell-matrix adhesion;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0071346 cellular response to type II interferon;GO:0043149 stress fiber assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A7U1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q09073-1", "uniprot_id": "ADT2_RAT", "mass": 32901.0, "length": 298, "protein_name": "ADP/ATP translocase 2", "gene_name": "Slc25a5", "organism": "Rat", "refseq_name": "ADP/ATP translocase 2", "refseq_ac": "NP_476443", "gene_names_uniprotkb": "Slc25a5; Ant2; Slc25a5-ps11", "gene_names_refseq": "Ant2; Slc25a5", "protein_names_uniprotkb": "ADP/ATP translocase 2; ADP,ATP carrier protein 2; ANT 2; Adenine nucleotide translocator 2; Solute carrier family 25 member 5", "protein_names_refseq": "ADP,ATP carrier protein 2; ADP/ATP translocase 2; ANT 2; adenine nucleotide translocator), member 5; solute carrier family 25 (mitochondrial carrier", "tax_id": 10116, "disease": "mitochondrial DNA depletion syndrome 12b (Disease Ontology:DOID:0080335); autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 2 (Disease Ontology:DOID:0111517); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); epilepsy (Disease Ontology:DOID:1826); mitochondrial metabolism disease (Disease Ontology:DOID:700)", "pathway": " (rno:25176); (R-RNO-83936); (R-RNO-9837999)", "pathway_count": 3, "publication_count": 8, "publication_id_list": "18683930;22673903;23267836;27458020;31213526;34502162;38843836;8399300", "class_list": "", "function": "ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell (By similarity). Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane (By similarity). In addition to its ADP:ATP antiporter activity, also involved in mitochondrial uncoupling and mitochondrial permeability transition pore (mPTP) activity. Plays a role in mitochondrial uncoupling by acting as a proton transporter: proton transport uncouples the proton flows via the electron transport chain and ATP synthase to reduce the efficiency of ATP production and cause mitochondrial thermogenesis. Proton transporter activity is inhibited by ADP:ATP antiporter activity, suggesting that SLC25A5/ANT2 acts as a master regulator of mitochondrial energy output by maintaining a delicate balance between ATP production (ADP:ATP antiporter activity) and thermogenesis (proton transporter activity). Proton transporter activity requires free fatty acids as cofactor, but does not transport it. Probably mediates mitochondrial uncoupling in tissues that do not express UCP1. Also plays a key role in mPTP opening, a non-specific pore that enables free passage of the mitochondrial membranes to solutes of up to 1.5 kDa, and which contributes to cell death. It is however unclear if SLC25A5/ANT2 constitutes a pore-forming component of mPTP or regulates it (By similarity). Acts as a regulator of mitophagy independently of ADP:ATP antiporter activity: promotes mitophagy via interaction with TIMM44, leading to inhibit the presequence translocase TIMM23, thereby promoting stabilization of PINK1 (By similarity). As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Catalyzes the exchange of ADP and ATP across the membrane., [UniProtKB, UniProtKB]; Knockdown of the major ANT isoforms, ANT2 and ANT3, did not collapse DeltaPsi after respiratory inhibition. These findings indicated that ANT did mediate mitochondrial ATP/ADP exchange in cancer cells. Erratum:[J Biol Chem. 2017 Oct 13;292(41):16969. doi: 10.1074/jbc.A116.734814. PMID: 29030537], [RefSeq, PubMed]; These findings demonstrate the gonadotropin stimulation of Btg2 in the ovary and, the physical interaction of Btg2 with Ant2 in mitochondria., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0031625 ubiquitin protein ligase binding;GO:0005471 ATP:ADP antiporter activity;GO:0015078 proton transmembrane transporter activity;GO:0000295 adenine nucleotide transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0016020 membrane;GO:0042645 mitochondrial nucleoid;GO:0045121 membrane raft", "go_biological_process": "GO:1901526 positive regulation of mitophagy;GO:0007059 chromosome segregation;GO:0008284 positive regulation of cell population proliferation;GO:0030218 erythrocyte differentiation;GO:1990830 cellular response to leukemia inhibitory factor", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q09073-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LVL2-1", "uniprot_id": "F1LVL2_RAT", "mass": 34707.0, "length": 306, "protein_name": "ICOS ligand", "gene_name": "Icoslg", "organism": "Rat", "refseq_name": "ICOS ligand isoform 1 precursor", "refseq_ac": "NP_001414305", "gene_names_uniprotkb": "Icoslg", "gene_names_refseq": "Icoslg; Icosl; RGD1562791", "protein_names_uniprotkb": "ICOS ligand; B7 homolog 2; B7-like protein Gl50; B7-related protein 1", "protein_names_refseq": "ICOS ligand isoform 1 precursor; icos ligand", "tax_id": 10116, "disease": "immunodeficiency 119 (Disease Ontology:DOID:0061085)", "pathway": " (R-RNO-9927354)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0042802 identical protein binding;GO:0048018 receptor ligand activity", "go_cellular_component": "GO:0016020 membrane;GO:0005886 plasma membrane;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0050852 T cell receptor signaling pathway;GO:0001817 regulation of cytokine production;GO:0032753 positive regulation of interleukin-4 production;GO:0061470 T follicular helper cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LVL2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "M0RDE8-1", "uniprot_id": "M0RDE8_RAT", "mass": 17020.0, "length": 148, "protein_name": "Tetratricopeptide repeat domain 32", "gene_name": "Ttc32", "organism": "Rat", "refseq_name": "tetratricopeptide repeat protein 32", "refseq_ac": "NP_001385619", "gene_names_uniprotkb": "Ttc32; LOC684830", "gene_names_refseq": "Ttc32", "protein_names_uniprotkb": "Tetratricopeptide repeat domain 32", "protein_names_refseq": "tetratricopeptide repeat protein 32", "tax_id": 10116, "disease": "", "pathway": " (rno:684830)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0RDE8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1M6X9-1", "uniprot_id": "F1M6X9_RAT", "mass": 41080.0, "length": 364, "protein_name": "Palmitoyltransferase", "gene_name": "Zdhhc11", "organism": "Rat", "refseq_name": "probable palmitoyltransferase ZDHHC11 isoform X1", "refseq_ac": "XP_038942712", "gene_names_uniprotkb": "Zdhhc11", "gene_names_refseq": "Zdhhc11; Zdhhc20; Znf399", "protein_names_uniprotkb": "Palmitoyltransferase; 2.3.1.225", "protein_names_refseq": "probable palmitoyltransferase ZDHHC11 isoform X1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.1.225;2.3.1.-;6.3.1.2", "go_molecular_function": "GO:0019706 protein-cysteine S-palmitoyltransferase activity;GO:0035591 signaling adaptor activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0016020 membrane", "go_biological_process": "GO:0006612 protein targeting to membrane;GO:0140374 antiviral innate immune response;GO:0002230 positive regulation of defense response to virus by host", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M6X9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4AD75-1", "uniprot_id": "D19L1_RAT", "mass": 84364.0, "length": 746, "protein_name": "Protein C-mannosyl-transferase DPY19L1", "gene_name": "Dpy19l1", "organism": "Rat", "refseq_name": "protein C-mannosyl-transferase DPY19L1", "refseq_ac": "NP_001178720", "gene_names_uniprotkb": "Dpy19l1", "gene_names_refseq": "Dpy19l1; RGD1305822", "protein_names_uniprotkb": "Protein C-mannosyl-transferase DPY19L1; 2.4.1.-; Dpy-19-like protein 1; Protein dpy-19 homolog 1", "protein_names_refseq": "dpy-19 like 1; dpy-19-like protein 1; probable C-mannosyltransferase DPY19L1; protein C-mannosyl-transferase DPY19L1; protein dpy-19 homolog 1", "tax_id": 10116, "disease": "", "pathway": " (rno:315496)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "C-mannosyltransferase that mediates the C-mannosylation tryptophan residues on target proteins. The reaction occurs on the luminal side of the endoplasmic reticulum and involves the transfer of a mannose unit from a dolichylphosphate mannose (Dol-P-Man) donor to an acceptor protein containing a WxxW consensus sequence. C-mannosylates the first two tryptophans in the WxxWxxWxxC sequence motif in thrombospondin (TSP) type-1 repeats of UNC5A. Regulates neurite extension during development., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.1.-", "go_molecular_function": "GO:0000030 mannosyltransferase activity;GO:0016757 glycosyltransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0016020 membrane", "go_biological_process": "GO:0018103 protein C-linked glycosylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4AD75-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LX68-1", "uniprot_id": "F1LX68_RAT", "mass": 59422.0, "length": 550, "protein_name": "Spermatogenesis associated, serine-rich 2", "gene_name": "Spats2", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Spats2", "gene_names_refseq": "", "protein_names_uniprotkb": "Spermatogenesis associated, serine-rich 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:300221)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LX68-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P23097-1", "uniprot_id": "MMP13_RAT", "mass": 53375.0, "length": 466, "protein_name": "Collagenase 3", "gene_name": "Mmp13", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Mmp13", "gene_names_refseq": "", "protein_names_uniprotkb": "Collagenase 3; 3.4.24.-; MMP-13; Matrix metalloproteinase-13; UMRCASE", "protein_names_refseq": "", "tax_id": 10116, "disease": "spondyloepimetaphyseal dysplasia, Missouri type (Disease Ontology:DOID:0080030); meningococcal meningitis (Disease Ontology:DOID:0080176); prostate cancer (Disease Ontology:DOID:10283); silicosis (Disease Ontology:DOID:10325); gastric ulcer (Disease Ontology:DOID:10808); urinary bladder cancer (Disease Ontology:DOID:11054); primary biliary cholangitis (Disease Ontology:DOID:12236); vulva cancer (Disease Ontology:DOID:1245); anodontia (Disease Ontology:DOID:13714); alcoholic liver cirrhosis (Disease Ontology:DOID:14018); brain ischemia (Disease Ontology:DOID:2316); arteriosclerosis (Disease Ontology:DOID:2349); invasive ductal carcinoma (Disease Ontology:DOID:3008); ovarian carcinoma (Disease Ontology:DOID:4001); cervical cancer (Disease Ontology:DOID:4362); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); abdominal aortic aneurysm (Disease Ontology:DOID:7693); periodontitis (Disease Ontology:DOID:824); osteoarthritis (Disease Ontology:DOID:8398); degenerative disc disease (Disease Ontology:DOID:90)", "pathway": " (rno:171052); (R-RNO-1442490); (R-RNO-1474228); (R-RNO-1592389); (R-RNO-2022090)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "2176215", "class_list": "", "function": "Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CCN2. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CCN2. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 21, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.4.21.4;3.4.24.7;3.4.22.38;3.4.24.-;3.4.24.34;3.4.22.1;3.4.24.17;3.4.24.22;3.4.22.15;3.4.24.24;3.4.24.23;3.4.24.35;3.4.22.27;3.4.24.80;3.4.24.65", "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0004222 metalloendopeptidase activity;GO:0004252 serine-type endopeptidase activity;GO:0008270 zinc ion binding;GO:0048306 calcium-dependent protein binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0031012 extracellular matrix;GO:0046581 intercellular canaliculus", "go_biological_process": "GO:0006508 proteolysis;GO:0007507 heart development;GO:0022617 extracellular matrix disassembly;GO:0030198 extracellular matrix organization;GO:0001666 response to hypoxia", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P23097-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5U311-1", "uniprot_id": "SLN13_RAT", "mass": 103655.0, "length": 907, "protein_name": "Schlafen family member 13", "gene_name": "Slfn13; Slfn9", "organism": "Rat", "refseq_name": "schlafen family member 13 isoform 1", "refseq_ac": "NP_001013992", "gene_names_uniprotkb": "Slfn13; Slfn9; Slfn13", "gene_names_refseq": "Slfn13; Slfn8; Slfn9; rSLFN13", "protein_names_uniprotkb": "Schlafen family member 13; 3.1.-.-; RNase S13; Ribonuclease S13; Schlafen-13; Schlafen13; rSLFN13", "protein_names_refseq": "RNase S13; ribonuclease S13; schlafen 8; schlafen family member 11; schlafen family member 13 isoform 1; schlafen family member 13; schlafen-13; schlafen13", "tax_id": 10116, "disease": "", "pathway": " (rno:303378)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "29563550", "class_list": "", "function": "Endoribonuclease that cleaves tRNAs and rRNAs (PubMed:29563550). Cleaves tRNAs 11 nucleotides from the 3'-terminus at the acceptor stem (PubMed:29563550). Does not act on tRNA(Sec) (PubMed:29563550)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 22, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A096MJD4;A0A096MKD0", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0016887 ATP hydrolysis activity;GO:0000049 tRNA binding;GO:0004521 RNA endonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0090734 site of DNA damage", "go_biological_process": "GO:0016078 tRNA decay;GO:0006338 chromatin remodeling;GO:0051607 defense response to virus;GO:0006974 DNA damage response;GO:2000134 negative regulation of G1/S transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5U311-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P62859-1", "uniprot_id": "RS28_RAT", "mass": 7841.0, "length": 69, "protein_name": "Small ribosomal subunit protein eS28", "gene_name": "Rps28-ps4; Rps28-ps5; Rps28", "organism": "Rat", "refseq_name": "small ribosomal subunit protein eS28", "refseq_ac": "NP_001099200", "gene_names_uniprotkb": "Rps28-ps4; Rps28-ps5; Rps28; Rps28-ps4; Rps28-ps5; Rps28l2; Rps28l3", "gene_names_refseq": "Rps28", "protein_names_uniprotkb": "Small ribosomal subunit protein eS28; 40S ribosomal protein S28", "protein_names_refseq": "40S ribosomal protein S28; small ribosomal subunit protein eS28", "tax_id": 10116, "disease": "Diamond-Blackfan anemia 15 with mandibulofacial dysostosis (Disease Ontology:DOID:0111894)", "pathway": " (rno:108352861); (rno:108353424); (rno:691531); (R-RNO-156827); (R-RNO-1799339); (R-RNO-6791226); (R-RNO-72649); (R-RNO-72689); (R-RNO-72695); (R-RNO-72702); (R-RNO-72706); (R-RNO-975956); (R-RNO-975957); (R-RNO-9954714); (R-RNO-9954716)", "pathway_count": 15, "publication_count": 1, "publication_id_list": "1679328", "class_list": "", "function": "Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P25112", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0045202 synapse;GO:0005840 ribosome;GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane;GO:0032040 small-subunit processome;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0042254 ribosome biogenesis;GO:0006412 translation;GO:0006364 rRNA processing;GO:0002181 cytoplasmic translation;GO:0042274 ribosomal small subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P62859-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1M9V0-1", "uniprot_id": "F1M9V0_RAT", "mass": 77901.0, "length": 741, "protein_name": "Ataxin 7-like 1", "gene_name": "Atxn7l1", "organism": "Rat", "refseq_name": "ataxin-7-like protein 1 isoform X20", "refseq_ac": "XP_063118159", "gene_names_uniprotkb": "Atxn7l1; Atxn7l4", "gene_names_refseq": "Atxn7l1; Atxn7l4; RGD1305730; RGD1564242", "protein_names_uniprotkb": "Ataxin 7-like 1", "protein_names_refseq": "ataxin-7-like protein 1 isoform X20", "tax_id": 10116, "disease": "spinocerebellar ataxia 7 (Disease Ontology:DOID:0050958)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M9V0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A5A6-1", "uniprot_id": "D4A5A6_RAT", "mass": 217206.0, "length": 1970, "protein_name": "DNA-directed RNA polymerase subunit", "gene_name": "Polr2a", "organism": "Rat", "refseq_name": "DNA-directed RNA polymerase II subunit RPB1", "refseq_ac": "NP_001413970", "gene_names_uniprotkb": "Polr2a", "gene_names_refseq": "Polr2a; Rpo2-1", "protein_names_uniprotkb": "DNA-directed RNA polymerase subunit; 2.7.7.6", "protein_names_refseq": "DNA-directed RNA polymerase II subunit RPB1; Polymerase (RNA II (DNA directed), large polypeptide; polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A", "tax_id": 10116, "disease": "Cockayne syndrome (Disease Ontology:DOID:2962); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083)", "pathway": " (rno:363633); (R-RNO-112382); (R-RNO-113418); (R-RNO-5578749); (R-RNO-674695); (R-RNO-6781823); (R-RNO-6782135); (R-RNO-6782210); (R-RNO-6796648); (R-RNO-6803529); (R-RNO-6807505); (R-RNO-72086); (R-RNO-72163); (R-RNO-72165); (R-RNO-72203); (R-RNO-73776); (R-RNO-73779); (R-RNO-75953); (R-RNO-75955); (R-RNO-76042); (R-RNO-77075); (R-RNO-9018519); (R-RNO-9770562)", "pathway_count": 23, "publication_count": 2, "publication_id_list": "12604794;22673903", "class_list": "", "function": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates., [UniProtKB, UniProtKB, UniProtKB]; PVHL specifically binds the hyperphosphorylated Rpb1 in a proline-hydroxylation-dependent manner, targeting it for ubiquitination, [RefSeq, PubMed]; RNA-dependent RNA polymerase that catalyzes the extension of a non-coding RNA (ncRNA) at the 3'-end using the four ribonucleoside triphosphates as substrates. An internal ncRNA sequence near the 3'-end serves as a template in a single-round Pol II-mediated RNA polymerization reaction. May decrease the stability of ncRNAs that repress Pol II-mediated gene transcription., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "6.5.1.1;3.6.4.13;2.3.2.32;3.1.3.16;2.7.7.7;2.7.7.6;5.6.2.3;2.7.7.19;5.2.1.8;2.1.1.348;2.3.2.27;3.1.11.-;2.7.11.22;2.7.11.23;2.7.11.24;3.1.3.53;2.3.1.48;3.6.4.10;3.1.27.-;2.7.7.52;5.6.2.4;3.4.19.12;2.7.1.78;2.1.1.56;3.1.26.n2", "go_molecular_function": "GO:0003968 RNA-directed RNA polymerase activity;GO:0000287 magnesium ion binding;GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005694 chromosome;GO:0000791 euchromatin", "go_biological_process": "GO:0033120 positive regulation of RNA splicing;GO:0006366 transcription by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter;GO:0006368 transcription elongation by RNA polymerase II;GO:0006353 DNA-templated transcription termination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D4A5A6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A5F6-1", "uniprot_id": "D4A5F6_RAT", "mass": 25876.0, "length": 232, "protein_name": "Brain-specific homeobox protein homolog", "gene_name": "Bsx", "organism": "Rat", "refseq_name": "brain-specific homeobox protein homolog", "refseq_ac": "NP_001178924", "gene_names_uniprotkb": "Bsx", "gene_names_refseq": "Bsx; RGD1565120", "protein_names_uniprotkb": "Brain-specific homeobox protein homolog", "protein_names_refseq": "brain-specific homeobox protein homolog", "tax_id": 10116, "disease": "", "pathway": " (rno:500982)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "20335227;31808568", "class_list": "", "function": "Circadian regulation and molecular role of the Bsx homeobox gene in the adult pineal gland., [RefSeq, PubMed]; DNA binding protein that function as transcriptional activator. Is essential for normal postnatal growth and nursing. Is an essential factor for neuronal neuropeptide Y and agouti-related peptide function and locomotory behavior in the control of energy balance., [UniProtKB, UniProtKB]; Ghrelin-induced changes in the AMPK-CPT1 pathway are associated with increased levels of AgRP and NPY mRNA expression through modulation of BSX, pCREB, and FoxO1 in a gender-independent manner., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007626 locomotory behavior;GO:0030154 cell differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D4A5F6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A5N6-1", "uniprot_id": "D4A5N6_RAT", "mass": 33665.0, "length": 301, "protein_name": "Retrotransposon Gag like 4", "gene_name": "Rtl4", "organism": "Rat", "refseq_name": "retrotransposon Gag like 4", "refseq_ac": "NP_001420066", "gene_names_uniprotkb": "Rtl4; LOC100363897; Zcchc16", "gene_names_refseq": "Rtl4; Zcchc16", "protein_names_uniprotkb": "Retrotransposon Gag like 4", "protein_names_refseq": "retrotransposon Gag like 4; retrotransposon Gag-like protein 4; zinc finger CCHC domain-containing protein 16; zinc finger CCHC-type containing 16; zinc finger, CCHC domain containing 16", "tax_id": 10116, "disease": "", "pathway": " (rno:680778)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003676 nucleic acid binding", "go_cellular_component": "", "go_biological_process": "GO:0050890 cognition;GO:0042415 norepinephrine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A5N6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A5R4-1", "uniprot_id": "D4A5R4_RAT", "mass": 14242.0, "length": 137, "protein_name": "Keratin-associated protein 4-7-like", "gene_name": "LOC100909494", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LOC100909494", "gene_names_refseq": "", "protein_names_uniprotkb": "Keratin-associated protein 4-7-like", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, 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"", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. 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RGD1564668", "protein_names_uniprotkb": "Leucine-rich repeat, Ig-like and transmembrane domains 2", "protein_names_refseq": "leucine-rich repeat, immunoglobulin-like and transmembrane domains 2; leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 2 precursor; leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 2", "tax_id": 10116, "disease": "", "pathway": " (rno:498594)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A7B9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A7K5-1", "uniprot_id": "D4A7K5_RAT", "mass": 135724.0, "length": 1187, "protein_name": "Phospholipid-transporting ATPase", "gene_name": "Atp11a", "organism": "Rat", "refseq_name": "phospholipid-transporting ATPase IH isoform 1", "refseq_ac": "NP_001100794", "gene_names_uniprotkb": "Atp11a", "gene_names_refseq": "Atp11a; Ua20", "protein_names_uniprotkb": "Phospholipid-transporting ATPase; 7.6.2.1", "protein_names_refseq": "ATPase, class VI, type 11A; UA20 protein-like; phospholipid-transporting ATPase IH isoform 1; probable phospholipid-transporting ATPase IH", "tax_id": 10116, "disease": "hypomyelinating leukodystrophy 24 (Disease Ontology:DOID:0070406); autosomal dominant nonsyndromic deafness 84 (Disease Ontology:DOID:0070604)", "pathway": " (rno:306600); (R-RNO-6798695); (R-RNO-936837)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "16641100;29393594", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "7.6.2.1;3.1.3.48;3.6.5.2;2.3.1.51;2.7.11.1;1.14.14.18;3.4.21.73;1.1.1.-;3.1.4.4;6.2.1.3;6.2.1.-;6.2.1.7;6.2.1.24;6.2.1.15;3.4.24.81;2.3.2.27;1.2.1.5;1.2.1.28;1.2.1.7;1.2.1.48;1.14.19.17;5.2.1.-;3.2.2.6;3.2.1.20;2.3.1.20;2.3.1.76", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0090555 phosphatidylethanolamine flippase activity;GO:0090556 phosphatidylserine floppase activity", "go_cellular_component": "GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0055037 recycling endosome;GO:0005789 endoplasmic reticulum membrane;GO:1990531 phospholipid-translocating ATPase complex", "go_biological_process": "GO:0010831 positive regulation of myotube differentiation;GO:0015914 phospholipid transport;GO:0001701 in utero embryonic development;GO:0045332 phospholipid translocation;GO:0097035 regulation of membrane lipid distribution", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D4A7K5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A7N0-1", "uniprot_id": "D4A7N0_RAT", "mass": 36884.0, "length": 324, "protein_name": "Olfactory receptor", "gene_name": "Or52h7", "organism": "Rat", "refseq_name": "olfactory receptor Olr153", "refseq_ac": "NP_001000167", "gene_names_uniprotkb": "Or52h7", "gene_names_refseq": "Olr153; Or52h7; ratchr1-162307080-162308054_ORF", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 153; olfactory receptor Olr153; olfactory receptor gene Olr153", "tax_id": 10116, "disease": "", "pathway": " (rno:293301)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A7N0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A813-1", "uniprot_id": "D4A813_RAT", "mass": 93041.0, "length": 796, "protein_name": "Zinc finger protein 51 like 1", "gene_name": "Zfp51l1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Zfp51l1; Zfp51", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger protein 51 like 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:499056)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000976 transcription cis-regulatory region binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A813-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A845-1", "uniprot_id": "D4A845_RAT", "mass": 16352.0, "length": 145, "protein_name": "Replication protein A3", "gene_name": "Rpa3", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Rpa3", "gene_names_refseq": "", "protein_names_uniprotkb": "Replication protein A3", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:296883); (R-RNO-110312); (R-RNO-110314); (R-RNO-110320); (R-RNO-174437); (R-RNO-176187); (R-RNO-3371453); (R-RNO-5358565); (R-RNO-5358606); (R-RNO-5651801); (R-RNO-5655862); (R-RNO-5656121); (R-RNO-5656169); (R-RNO-5685938); (R-RNO-5685942); (R-RNO-5693537); (R-RNO-5693607); (R-RNO-5696395); (R-RNO-5696397); (R-RNO-5696400); (R-RNO-6782135); (R-RNO-6782210); (R-RNO-6783310); (R-RNO-6804756); (R-RNO-68962); (R-RNO-69166); (R-RNO-69473)", "pathway_count": 27, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003684 damaged DNA binding;GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0035861 site of double-strand break;GO:0005662 DNA replication factor A complex", "go_biological_process": "GO:0006281 DNA repair;GO:0042127 regulation of cell population proliferation;GO:0006284 base-excision repair;GO:0006260 DNA replication;GO:0007346 regulation of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A845-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A849-1", "uniprot_id": "D4A849_RAT", "mass": 66304.0, "length": 576, "protein_name": "Polypeptide N-acetylgalactosaminyltransferase", "gene_name": "Galnt12", "organism": "Rat", "refseq_name": "polypeptide N-acetylgalactosaminyltransferase 12", "refseq_ac": "NP_001413928", "gene_names_uniprotkb": "Galnt12", "gene_names_refseq": "Galnt12; RGD1562001", "protein_names_uniprotkb": "Polypeptide N-acetylgalactosaminyltransferase; 2.4.1.-; Protein-UDP acetylgalactosaminyltransferase", "protein_names_refseq": "UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12); polypeptide N-acetylgalactosaminyltransferase 12", "tax_id": 10116, "disease": "colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (rno:313233); (R-RNO-913709)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward non-glycosylated peptides such as Muc5AC, Muc1a and EA2, and no detectable activity with Muc2 and Muc7. Displays enzymatic activity toward the Gal-NAc-Muc5AC glycopeptide, but no detectable activity to mono-GalNAc-glycosylated Muc1a, Muc2, Muc7 and EA2. May play an important role in the initial step of mucin-type oligosaccharide biosynthesis in digestive organs., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.1.-;2.4.1.41", "go_molecular_function": "GO:0046872 metal ion binding;GO:0030246 carbohydrate binding;GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0006493 protein O-linked glycosylation;GO:0016266 protein O-linked glycosylation via N-acetyl-galactosamine", "synthesized_glycan_count": 7434, "hit_score": 0.1, "record_id": "D4A849-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A862-1", "uniprot_id": "D4A862_RAT", "mass": 8209.0, "length": 70, "protein_name": "Large ribosomal subunit protein eL38", "gene_name": "Rpl38l4", "organism": "Rat", "refseq_name": "large ribosomal subunit protein eL38-like", "refseq_ac": "XP_038953298", "gene_names_uniprotkb": "Rpl38l4; AABR07032520.2; LOC680512", "gene_names_refseq": "Rpl38l4", "protein_names_uniprotkb": "Large ribosomal subunit protein eL38; 60S ribosomal protein L38", "protein_names_refseq": "large ribosomal subunit protein eL38-like", "tax_id": 10116, "disease": "otitis media (Disease Ontology:DOID:10754)", "pathway": " (rno:680512)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0006412 translation;GO:0022618 protein-RNA complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A862-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A8B0-1", "uniprot_id": "D4A8B0_RAT", "mass": 78724.0, "length": 696, "protein_name": "SEC14-like lipid binding 5", "gene_name": "Sec14l5", "organism": "Rat", "refseq_name": "SEC14-like protein 5", "refseq_ac": "NP_001129182", "gene_names_uniprotkb": "Sec14l5", "gene_names_refseq": "RGD1564638; Sec14l5", "protein_names_uniprotkb": "SEC14-like lipid binding 5", "protein_names_refseq": "SEC14-like 5 protein; SEC14-like protein 5", "tax_id": 10116, "disease": "", "pathway": " (rno:287060)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A8B0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A8L7-1", "uniprot_id": "D4A8L7_RAT", "mass": 27134.0, "length": 235, "protein_name": "CHD1 helical C-terminal domain containing 1", "gene_name": "Chct1", "organism": "Rat", "refseq_name": "CHD1 helical C-terminal domain containing 1 isoform a", "refseq_ac": "NP_001417122", "gene_names_uniprotkb": "Chct1; RGD1310166", "gene_names_refseq": "C10h17orf64; Chct1; RGD1310166", "protein_names_uniprotkb": "CHD1 helical C-terminal domain containing 1", "protein_names_refseq": "CHD1 helical C-terminal domain containing 1 isoform a; CHD1 helical C-terminal domain containing protein 1; uncharacterized protein C17orf64 homolog", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A8L7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A8M3-1", "uniprot_id": "D4A8M3_RAT", "mass": 47451.0, "length": 426, "protein_name": "Fc receptor-like B", "gene_name": "Fcrlb", "organism": "Rat", "refseq_name": "Fc receptor-like B precursor", "refseq_ac": "NP_001178860", "gene_names_uniprotkb": "Fcrlb", "gene_names_refseq": "Fcrlb; RGD1563018", "protein_names_uniprotkb": "Fc receptor-like B", "protein_names_refseq": "Fc receptor-like B precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:498275)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0050777 negative regulation of immune response;GO:0016064 immunoglobulin mediated immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A8M3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A8V0-1", "uniprot_id": "D4A8V0_RAT", "mass": 48316.0, "length": 446, "protein_name": "CUGBP, Elav-like family member 5", "gene_name": "Celf5", "organism": "Rat", "refseq_name": "CUGBP Elav-like family member 5 isoform X1", "refseq_ac": "XP_038934951", "gene_names_uniprotkb": "Celf5", "gene_names_refseq": "Brunol5; Celf5; RGD1565016", "protein_names_uniprotkb": "CUGBP, Elav-like family member 5", "protein_names_refseq": "CUGBP Elav-like family member 5 isoform X1", "tax_id": 10116, "disease": "myotonic dystrophy type 1 (Disease Ontology:DOID:11722); dilated cardiomyopathy (Disease Ontology:DOID:12930)", "pathway": " (rno:314647)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006376 mRNA splice site recognition;GO:0000381 regulation of alternative mRNA splicing, via spliceosome;GO:0006397 mRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A8V0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A900-1", "uniprot_id": "D4A900_RAT", "mass": 135842.0, "length": 1186, "protein_name": "Filamin A interacting protein 1-like", "gene_name": "Filip1l", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Filip1l", "gene_names_refseq": "", "protein_names_uniprotkb": "Filamin A interacting protein 1-like", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "16641100;22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005813 centrosome;GO:0015629 actin cytoskeleton", "go_biological_process": "GO:1903119 protein localization to actin cytoskeleton;GO:0061525 hindgut development;GO:0008104 intracellular protein localization;GO:0009306 protein secretion;GO:0010498 proteasomal protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D4A900-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A926-1", "uniprot_id": "D4A926_RAT", "mass": 34987.0, "length": 312, "protein_name": "Olfactory receptor", "gene_name": "Or6n1", "organism": "Rat", "refseq_name": "olfactory receptor Olr1589", "refseq_ac": "NP_001000083", "gene_names_uniprotkb": "Or6n1", "gene_names_refseq": "Olr1589; Or6n1", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1589; olfactory receptor Olr1589; olfactory receptor gene Olr1589", "tax_id": 10116, "disease": "", "pathway": " (rno:289251)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A926-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A961-1", "uniprot_id": "D4A961_RAT", "mass": 33499.0, "length": 306, "protein_name": "Solute carrier family 25 member 48", "gene_name": "Slc25a48", "organism": "Rat", "refseq_name": "solute carrier family 25, member 48", "refseq_ac": "NP_001419223", "gene_names_uniprotkb": "Slc25a48", "gene_names_refseq": "RGD1563703; Slc25a48", "protein_names_uniprotkb": "Solute carrier family 25 member 48", "protein_names_refseq": "solute carrier family 25, member 48", "tax_id": 10116, "disease": "", "pathway": " (rno:361206)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mitochondrial transporter that transports choline across the inner mitochondrial membrane., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.8.-.-", "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0015220 choline transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0015871 choline transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A961-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A9A3-1", "uniprot_id": "D4A9A3_RAT", "mass": 27516.0, "length": 250, "protein_name": "Centromere protein V", "gene_name": "Cenpv", "organism": "Rat", "refseq_name": "centromere protein V", "refseq_ac": "NP_001385800", "gene_names_uniprotkb": "Cenpv", "gene_names_refseq": "Cenpv; Prr6; RGD1565681", "protein_names_uniprotkb": "Centromere protein V; Proline-rich protein 6", "protein_names_refseq": "centromere protein V; proline rich 6; proline-rich polypeptide 6", "tax_id": 10116, "disease": "", "pathway": " (rno:501702)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Required for distribution of pericentromeric heterochromatin in interphase nuclei and for centromere formation and organization, chromosome alignment and cytokinesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008017 microtubule binding;GO:0046872 metal ion binding;GO:0016846 carbon-sulfur lyase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0031965 nuclear membrane;GO:0051233 spindle midzone", "go_biological_process": "GO:0033044 regulation of chromosome organization;GO:0051382 kinetochore assembly;GO:0031508 pericentric heterochromatin formation;GO:0007059 chromosome segregation;GO:0051225 spindle assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A9A3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A9C8-1", "uniprot_id": "D4A9C8_RAT", "mass": 14647.0, "length": 132, "protein_name": "40S ribosomal protein S12", "gene_name": "Rps12l10", "organism": "Rat", "refseq_name": "small ribosomal subunit protein eS12-like", "refseq_ac": "XP_038948801", "gene_names_uniprotkb": "Rps12l10; LOC108352809", "gene_names_refseq": "Rps12l10", "protein_names_uniprotkb": "40S ribosomal protein S12", "protein_names_refseq": "small ribosomal subunit protein eS12-like", "tax_id": 10116, "disease": "", "pathway": " (rno:108352809)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Subunit of the 40S ribosomal complex., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:1990145 maintenance of translational fidelity;GO:0042274 ribosomal small subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A9C8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A9G1-1", "uniprot_id": "D4A9G1_RAT", "mass": 46394.0, "length": 407, "protein_name": "60S ribosomal protein L3-like", "gene_name": "Rpl3l", "organism": "Rat", "refseq_name": "ribosomal protein uL3-like", "refseq_ac": "NP_001178518", "gene_names_uniprotkb": "Rpl3l", "gene_names_refseq": "Rpl3l", "protein_names_uniprotkb": "60S ribosomal protein L3-like", "protein_names_refseq": "60S ribosomal protein L3-like; ribosomal protein uL3-like", "tax_id": 10116, "disease": "dilated cardiomyopathy 2D (Disease Ontology:DOID:0081160)", "pathway": " (rno:287122); (R-RNO-156827); (R-RNO-1799339); (R-RNO-6791226); (R-RNO-72689); (R-RNO-72706); (R-RNO-975956); (R-RNO-975957); (R-RNO-9954709); (R-RNO-9954714); (R-RNO-9954716)", "pathway_count": 11, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Heart- and skeletal muscle-specific component of the ribosome, which regulates muscle function. Component of the large ribosomal subunit in striated muscle cells: replaces the RPL3 paralog in the ribosome in these cells. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Inhibits myotube growth and muscle function., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0016202 regulation of striated muscle tissue development;GO:0006412 translation;GO:0010832 negative regulation of myotube differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A9G1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A9G5-1", "uniprot_id": "D4A9G5_RAT", "mass": 83097.0, "length": 717, "protein_name": "Dpy-19 like C-mannosyltransferase 3", "gene_name": "Dpy19l3", "organism": "Rat", "refseq_name": "probable C-mannosyltransferase DPY19L3", "refseq_ac": "NP_001129307", "gene_names_uniprotkb": "Dpy19l3", "gene_names_refseq": "Dpy19l3; RGD1308334", "protein_names_uniprotkb": "Dpy-19 like C-mannosyltransferase 3", "protein_names_refseq": "dpy-19-like 3; probable C-mannosyltransferase DPY19L3; protein dpy-19 homolog 3", "tax_id": 10116, "disease": "", "pathway": " (rno:308519)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000030 mannosyltransferase activity;GO:0016757 glycosyltransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A9G5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A9J4-1", "uniprot_id": "D4A9J4_RAT", "mass": 146157.0, "length": 1305, "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "Nsd2", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Nsd2; Whsc1", "gene_names_refseq": "", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase NSD2; 2.1.1.357; H3-K36-HMTase; Histone-lysine N-methyltransferase, H3 lysine-36 specific; Multiple myeloma SET domain-containing protein; Nuclear SET domain-containing protein 2; Nuclear receptor-binding SET domain-containing protein 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "Wolf-Hirschhorn syndrome (Disease Ontology:DOID:0050460); Sotos syndrome 1 (Disease Ontology:DOID:0112103); syndrome (Disease Ontology:DOID:225); lung non-small cell carcinoma (Disease Ontology:DOID:3908)", "pathway": " (R-RNO-3214841); (R-RNO-5693565); (R-RNO-5693571); (R-RNO-5693607); (R-RNO-69473)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.2.26;2.1.1.370;2.1.1.371;1.14.11.69;1.14.11.66;2.1.1.357;2.7.11.1;3.4.19.-;2.3.2.27;2.1.1.359;2.1.1.367;3.1.3.16;2.3.2.-;3.1.-.-;2.1.1.-;2.1.1.354;2.3.1.48;2.3.1.-;2.3.2.23;3.6.-.-", "go_molecular_function": "GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0042054 histone methyltransferase activity;GO:0043565 sequence-specific DNA binding;GO:0046975 histone H3K36 methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0000785 chromatin", "go_biological_process": "GO:0003290 atrial septum secundum morphogenesis;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0060348 bone development;GO:0003289 atrial septum primum morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A9J4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A9M5-1", "uniprot_id": "D4A9M5_RAT", "mass": 28446.0, "length": 268, "protein_name": "Ly6/PLAUR domain-containing protein 5", "gene_name": "Lypd5", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Lypd5", "gene_names_refseq": "", "protein_names_uniprotkb": "Ly6/PLAUR domain-containing protein 5", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:502308); 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Spmip6", "protein_names_uniprotkb": "Sperm microtubule inner protein 6", "protein_names_refseq": "sperm microtubule inner protein 6 isoform X1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0043014 alpha-tubulin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0030317 flagellated sperm motility", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A9U1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A9W3-1", "uniprot_id": "D4A9W3_RAT", "mass": 67625.0, "length": 632, "protein_name": "D-glutamate cyclase, mitochondrial", "gene_name": "Dglucy", "organism": "Rat", "refseq_name": "D-glutamate cyclase, mitochondrial isoform X1", "refseq_ac": "XP_017449723", "gene_names_uniprotkb": "Dglucy; RGD1311756", "gene_names_refseq": "Dglucy; RGD1311756", "protein_names_uniprotkb": "D-glutamate cyclase, mitochondrial; 4.2.1.48", "protein_names_refseq": "D-glutamate cyclase, mitochondrial isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:362769)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "D-glutamate cyclase that converts D-glutamate to 5-oxo-D-proline., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "4.2.1.48", "go_molecular_function": "GO:0047820 D-glutamate cyclase activity;GO:0016829 lyase activity", "go_cellular_component": "GO:0005759 mitochondrial matrix;GO:0005829 cytosol", "go_biological_process": "GO:0006536 glutamate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A9W3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A9Y0-1", "uniprot_id": "D4A9Y0_RAT", "mass": 23403.0, "length": 220, "protein_name": "Stromal cell-derived factor 2-like 1", "gene_name": "Sdf2l1", "organism": "Rat", "refseq_name": "stromal cell-derived factor 2-like protein 1 precursor", "refseq_ac": "NP_001102903", "gene_names_uniprotkb": "Sdf2l1", "gene_names_refseq": "Sdf2l1", "protein_names_uniprotkb": "Stromal cell-derived factor 2-like 1", "protein_names_refseq": "stromal cell-derived factor 2-like protein 1 precursor; stromal cell-derived factor 2-like protein 1", "tax_id": 10116, "disease": "type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (rno:680945)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23444373", "class_list": "", "function": "SDF2L1 increases the time that misfolded proteins have to achieve a correctly folded conformation and thus that SDF2L1 can act as a buffer for substrate availability for ERAD in pancreatic beta-cells., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051087 protein-folding chaperone binding;GO:0051117 ATPase binding;GO:0051787 misfolded protein binding", "go_cellular_component": "GO:0034663 endoplasmic reticulum chaperone complex;GO:0005576 extracellular region;GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0101031 protein folding chaperone complex", "go_biological_process": "GO:0042981 regulation of apoptotic process;GO:0036503 ERAD pathway;GO:0034976 response to endoplasmic reticulum stress;GO:0042026 protein refolding;GO:0071218 cellular response to misfolded protein", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A9Y0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4AA28-1", "uniprot_id": "D4AA28_RAT", "mass": 35255.0, "length": 319, "protein_name": "Olfactory receptor", "gene_name": "Or13c7", "organism": "Rat", "refseq_name": "olfactory receptor Olr840", "refseq_ac": "NP_001000414", "gene_names_uniprotkb": "Or13c7; Or13c7c", "gene_names_refseq": "Olr840; Or13c7", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 840; olfactory receptor Olr840; olfactory receptor gene Olr840", "tax_id": 10116, "disease": "", "pathway": " (rno:298733); (rno:298734)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4AA28-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4AA31-1", "uniprot_id": "D4AA31_RAT", "mass": 55562.0, "length": 493, "protein_name": "Lysosomal Pro-X carboxypeptidase", "gene_name": "Prcp", "organism": "Rat", "refseq_name": "lysosomal Pro-X carboxypeptidase precursor", "refseq_ac": "NP_001099751", "gene_names_uniprotkb": "Prcp", "gene_names_refseq": "Prcp", "protein_names_uniprotkb": "Lysosomal Pro-X carboxypeptidase; 3.4.16.2; Proline carboxypeptidase; Prolylcarboxypeptidase", "protein_names_refseq": "lysosomal Pro-X carboxypeptidase precursor; lysosomal Pro-X carboxypeptidase; prolylcarboxypeptidase (angiotensinase C)", "tax_id": 10116, "disease": "brain infarction (Disease Ontology:DOID:3454)", "pathway": " (rno:293118); (R-RNO-6798695); (R-RNO-9970672)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "19018804;19620781;24627106;25218829;26509155;29393594", "class_list": "", "function": "Chronic ethanol regimen is sufficient to promote the enhanced RAS activity-induced decrease in the production of cardiac collagen via downregulated angiotensinase C, leading to the further deterioration of LV systolic dysfunction in SHRs, [RefSeq, PubMed]; Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH., [UniProtKB, UniProtKB]; ENOS inhibition in spontaneously hypertensive rats induces or enhances an inverse reciprocal interaction between hypothalamus and left ventricle involving the renin-angiotensin system and vasopressin., [RefSeq, PubMed]; It appears unlikely that PRCP function is regulated by the renin-angiotensin system or by afterload conditions., [RefSeq, PubMed]; PRCP is an important component of melanocortin signaling and weight maintenance via control of active alpha-MSH1-13 levels., [RefSeq, PubMed]; Suggest that in renovascular hypertension the repression of increases in systolic blood pressure and reversal of mesenteric artery remodelling by rutaecarpine may be related to increased expression of PRCP., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "7.6.2.1;3.6.5.2;3.6.1.29;3.4.16.2;2.5.1.18;3.4.21.34;3.1.3.5;3.1.3.2;3.1.3.48;3.4.23.-;2.3.1.51;2.3.1.23;2.3.1.67;2.3.1.25;2.3.2.27;3.6.1.-;3.2.1.25;3.5.1.92;3.1.3.-;3.2.1.20", "go_molecular_function": "GO:0008239 dipeptidyl-peptidase activity;GO:0004185 serine-type carboxypeptidase activity;GO:0004181 metallocarboxypeptidase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0045178 basal part of cell;GO:0005764 lysosome", "go_biological_process": "GO:0002155 regulation of thyroid hormone receptor signaling pathway;GO:0043535 regulation of blood vessel endothelial cell migration;GO:0002003 angiotensin maturation;GO:0097009 energy homeostasis;GO:0042593 glucose homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "D4AA31-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4AA49-1", "uniprot_id": "D4AA49_RAT", "mass": 140895.0, "length": 1289, "protein_name": "Contactin associated protein family member 3", "gene_name": "Cntnap3", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Cntnap3", "gene_names_refseq": "", "protein_names_uniprotkb": "Contactin associated protein family member 3", "protein_names_refseq": "", "tax_id": 10116, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041); autosomal recessive intellectual developmental disorder (Disease Ontology:DOID:0060308)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0043204 perikaryon;GO:0045202 synapse;GO:0016020 membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0007165 signal transduction;GO:0007399 nervous system development;GO:0008542 visual learning;GO:0050808 synapse organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4AA49-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4AA55-1", "uniprot_id": "D4AA55_RAT", "mass": 15402.0, "length": 132, "protein_name": "EF-hand calcium binding domain 10", "gene_name": "Efcab10", "organism": "Rat", "refseq_name": "EF-hand calcium-binding domain-containing protein 10", "refseq_ac": "NP_001102176", "gene_names_uniprotkb": "Efcab10", "gene_names_refseq": "Efcab10; RGD1307943", "protein_names_uniprotkb": "EF-hand calcium binding domain 10", "protein_names_refseq": "EF-hand calcium-binding domain-containing protein 10", "tax_id": 10116, "disease": "", "pathway": " (rno:362727)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, 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chemokine (C-C motif) receptor 8", "tax_id": 10116, "disease": "asthma (Disease Ontology:DOID:2841); pulmonary fibrosis (Disease Ontology:DOID:3770)", "pathway": " (rno:301066); (R-RNO-380108); (R-RNO-418594)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "31314754", "class_list": "", "function": "We show a novel method for formation of Embryoid bodies (EBs) from mesenchymal stem cells under stress and demonstrate that the induction of FoxP3+ CCR8+ EBs is dependent upon CCL1 gradients which mediate cell proliferation, migration and invasion of mTregs. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0016493 C-C chemokine receptor activity;GO:0019957 C-C chemokine binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0006935 chemotaxis;GO:0006955 immune response;GO:0007186 G protein-coupled receptor signaling pathway;GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0019722 calcium-mediated signaling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4ADE0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4ADL6-1", "uniprot_id": "D4ADL6_RAT", "mass": 55464.0, "length": 495, "protein_name": "Zinc finger and SCAN domain containing 22", "gene_name": "Zscan22", "organism": "Rat", "refseq_name": "zinc finger and SCAN domain containing 22 isoform a", "refseq_ac": "NP_001395733", "gene_names_uniprotkb": "Zscan22; 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4ADY4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4ADZ9-1", "uniprot_id": "D4ADZ9_RAT", "mass": 74641.0, "length": 660, "protein_name": "Pseudouridylate synthase 7 homolog", "gene_name": "Pus7", "organism": "Rat", "refseq_name": "pseudouridylate synthase 7 homolog", "refseq_ac": "NP_001164060", "gene_names_uniprotkb": "Pus7", "gene_names_refseq": "Pus7; RGD1307054", "protein_names_uniprotkb": "Pseudouridylate synthase 7 homolog", "protein_names_refseq": "pseudouridylate synthase 7 homolog", "tax_id": 10116, "disease": "intellectual developmental disorder with abnormal behavior, microcephaly, and short stature (Disease Ontology:DOID:0081265); intellectual disability (Disease Ontology:DOID:1059); microcephaly (Disease Ontology:DOID:10907)", "pathway": " (rno:296751)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Pseudouridylate synthase that catalyzes pseudouridylation of RNAs. Acts as a regulator of protein synthesis in embryonic stem cells by mediating pseudouridylation of RNA fragments derived from tRNAs (tRFs): pseudouridylated tRFs inhibit translation by targeting the translation initiation complex. Also catalyzes pseudouridylation of mRNAs: mediates pseudouridylation of mRNAs with the consensus sequence 5'-UGUAG-3'. Acts as a regulator of pre-mRNA splicing by mediating pseudouridylation of pre-mRNAs at locations associated with alternatively spliced regions. Pseudouridylation of pre-mRNAs near splice sites directly regulates mRNA splicing and mRNA 3'-end processing. In addition to mRNAs and tRNAs, binds other types of RNAs, such as snRNAs, Y RNAs and vault RNAs, suggesting that it can catalyze pseudouridylation of many RNA types., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.4.99.12;5.4.99.-;5.4.99.25", "go_molecular_function": "GO:0003723 RNA binding;GO:0019899 enzyme binding;GO:0009982 pseudouridine synthase activity;GO:0160150 tRNA pseudouridine(13) synthase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0031119 tRNA pseudouridine synthesis;GO:0006397 mRNA processing;GO:0008380 RNA splicing;GO:1902036 regulation of hematopoietic stem cell differentiation;GO:0017148 negative regulation of translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4ADZ9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4AE55-1", "uniprot_id": "D4AE55_RAT", "mass": 34971.0, "length": 306, "protein_name": "Olfactory receptor", "gene_name": "Or5ac25", "organism": "Rat", "refseq_name": "olfactory receptor Olr1528", "refseq_ac": "NP_001001099", "gene_names_uniprotkb": "Or5ac25; Olr1528", "gene_names_refseq": "Olfr209; Olr1528; Or5ac25", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1528; olfactory receptor 209; olfactory receptor Olr1528; olfactory receptor gene Olr1528", "tax_id": 10116, "disease": "", "pathway": " (rno:405995)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4AEF2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4AEL3-1", "uniprot_id": "D4AEL3_RAT", "mass": 11417.0, "length": 111, "protein_name": "Distal membrane arm assembly component 1", "gene_name": "Dmac1", "organism": "Rat", "refseq_name": "distal membrane-arm assembly complex protein 1", "refseq_ac": "NP_001193604", "gene_names_uniprotkb": "Dmac1; 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Glb1l4", "protein_names_uniprotkb": "Beta-galactosidase; 3.2.1.23", "protein_names_refseq": "beta-galactosidase-like protein isoform 1", "tax_id": 10116, "disease": "", "pathway": " (rno:494244)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "19092116", "class_list": "", "function": "Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans., [UniProtKB, UniProtKB]; GLB1L4 may play various roles in principal cell differentiation and sperm maturation., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004565 beta-galactosidase activity", "go_cellular_component": "", "go_biological_process": "GO:0005975 carbohydrate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "E9PSK3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E9PSU7-1", "uniprot_id": "E9PSU7_RAT", "mass": 82123.0, "length": 738, "protein_name": "Interleukin-12 receptor subunit beta-1", "gene_name": "Il12rb1", "organism": "Rat", "refseq_name": "interleukin-12 receptor subunit beta-1 precursor", "refseq_ac": "NP_001164075", "gene_names_uniprotkb": "Il12rb1", "gene_names_refseq": "Il12rb1; Il12rb", "protein_names_uniprotkb": "Interleukin-12 receptor subunit beta-1; IL-12 receptor beta component", "protein_names_refseq": "interleukin 12 receptor, beta 1; interleukin-12 receptor subunit beta-1 precursor", "tax_id": 10116, "disease": "immunodeficiency 30 (Disease Ontology:DOID:0111990); primary biliary cholangitis (Disease Ontology:DOID:12236); asthma (Disease Ontology:DOID:2841); severe acute respiratory syndrome (Disease Ontology:DOID:2945); pulmonary tuberculosis (Disease Ontology:DOID:2957); tuberculosis (Disease Ontology:DOID:399); allergic rhinitis (Disease Ontology:DOID:4481)", "pathway": " (rno:171333); (R-RNO-9020591); (R-RNO-9020933)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Also associates with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015026 coreceptor activity;GO:0019955 cytokine binding;GO:0004896 cytokine receptor activity;GO:0016517 interleukin-12 receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex;GO:0009897 external side of plasma membrane;GO:0042022 interleukin-12 receptor complex;GO:0072536 interleukin-23 receptor complex", "go_biological_process": "GO:0051142 positive regulation of NK T cell proliferation;GO:0008284 positive regulation of cell population proliferation;GO:0018108 peptidyl-tyrosine phosphorylation;GO:0035722 interleukin-12-mediated signaling pathway;GO:0002230 positive regulation of defense response to virus by host", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E9PSU7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E9PSW8-1", "uniprot_id": "E9PSW8_RAT", "mass": 103316.0, "length": 916, "protein_name": "Centromere protein C", "gene_name": "Cenpc", "organism": "Rat", "refseq_name": "centromere protein C isoform 1", "refseq_ac": "NP_001004098", "gene_names_uniprotkb": "Cenpc; Cenpc1", "gene_names_refseq": "Cenpc1; Cenpc", "protein_names_uniprotkb": "Centromere protein C; Centromere autoantigen C; Centromere protein C 1", "protein_names_refseq": "centromere autoantigen C; centromere protein C isoform 1; centromere protein C1", "tax_id": 10116, "disease": "CREST syndrome (Disease Ontology:DOID:0060218); liver cirrhosis (Disease Ontology:DOID:5082)", "pathway": " (rno:305270); (R-RNO-141430); (R-RNO-141444); (R-RNO-2467813); (R-RNO-2500257); (R-RNO-5663220); (R-RNO-606279); (R-RNO-68877); (R-RNO-9648025)", "pathway_count": 9, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0019237 centromeric DNA binding", "go_cellular_component": "GO:0000939 inner kinetochore;GO:0005654 nucleoplasm;GO:0016604 nuclear body;GO:0000776 kinetochore;GO:0000779 condensed chromosome, centromeric region", "go_biological_process": "GO:0051315 attachment of mitotic spindle microtubules to kinetochore;GO:0051382 kinetochore assembly;GO:0051455 spindle attachment to meiosis I kinetochore;GO:0000278 mitotic cell cycle;GO:0007059 chromosome segregation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "E9PSW8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E9PT30-1", "uniprot_id": "E9PT30_RAT", "mass": 37735.0, "length": 338, "protein_name": "Intelectin 1", "gene_name": "Itln1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Itln1", "gene_names_refseq": "", "protein_names_uniprotkb": "Intelectin 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-6803157)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0070492 oligosaccharide binding;GO:0042802 identical protein binding;GO:0005509 calcium ion binding;GO:0046872 metal ion binding;GO:0030246 carbohydrate binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0043235 receptor complex;GO:0045121 membrane raft;GO:0031526 brush border membrane", "go_biological_process": "GO:0001934 positive regulation of protein phosphorylation;GO:0070207 protein homotrimerization;GO:0046326 positive regulation of D-glucose import;GO:0009624 response to nematode", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E9PT30-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E9PT49-1", "uniprot_id": "E9PT49_RAT", "mass": 157359.0, "length": 1459, "protein_name": "Regulatory factor X, 7", "gene_name": "Rfx7", "organism": "Rat", "refseq_name": "DNA-binding protein RFX7", "refseq_ac": "NP_001120962", "gene_names_uniprotkb": "Rfx7", "gene_names_refseq": "Rfx7; Rfxdc2", "protein_names_uniprotkb": "Regulatory factor X, 7", "protein_names_refseq": "DNA-binding protein RFX7; regulatory factor X domain containing 2 homolog", "tax_id": 10116, "disease": "autosomal dominant intellectual developmental disorder 71 with behavioral abnormalities (Disease Ontology:DOID:0061044)", "pathway": " (rno:315804)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 8, "predicted_n_glycosites": 0, "predicted_o_glycosites": 8, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:1990837 sequence-specific double-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "E9PT49-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E9PT59-1", "uniprot_id": "E9PT59_RAT", "mass": 177389.0, "length": 1589, "protein_name": "Rho guanine nucleotide exchange factor 5", "gene_name": "Arhgef5", "organism": "Rat", "refseq_name": "rho guanine nucleotide exchange factor 5", "refseq_ac": "NP_001414344", "gene_names_uniprotkb": "Arhgef5", "gene_names_refseq": "Arhgef5; Tim1", "protein_names_uniprotkb": "Rho guanine nucleotide exchange factor 5", "protein_names_refseq": "Rho guanine nucleotide exchange factor (GEF) 5; rho guanine nucleotide exchange factor 5", "tax_id": 10116, "disease": "", "pathway": " (rno:140898); (R-RNO-193648); (R-RNO-416482); (R-RNO-8980692); (R-RNO-9013026); (R-RNO-9013106); (R-RNO-9013148); (R-RNO-9013149); (R-RNO-9013408)", "pathway_count": 9, "publication_count": 2, "publication_id_list": "14643017;22673903", "class_list": "", "function": "Expression studies show that mr-gef is expressed by young neurons of the developing rodent CNS but not by progenitor cells in the ventricular zone (VZ)., [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0032956 regulation of actin cytoskeleton organization;GO:0035556 intracellular signal transduction;GO:0043547 positive regulation of GTPase activity;GO:1904591 positive regulation of protein import;GO:0030036 actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "E9PT59-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E9PT83-1", "uniprot_id": "E9PT83_RAT", "mass": 341899.0, "length": 2985, "protein_name": "Centromere protein F", "gene_name": "Cenpf", "organism": "Rat", "refseq_name": "centromere protein F isoform X1", "refseq_ac": "XP_038946326", "gene_names_uniprotkb": "Cenpf", "gene_names_refseq": "Cenpf; Lek1", "protein_names_uniprotkb": "Centromere protein F", "protein_names_refseq": "centromere protein F isoform X1", "tax_id": 10116, "disease": "Stromme syndrome (Disease Ontology:DOID:0110595); dilated cardiomyopathy (Disease Ontology:DOID:12930)", "pathway": " (rno:257649); (R-RNO-141430); (R-RNO-141444); (R-RNO-2467813); (R-RNO-2500257); (R-RNO-5663220); (R-RNO-68877); (R-RNO-9648025)", "pathway_count": 8, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008017 microtubule binding;GO:0042803 protein homodimerization activity;GO:0070840 dynein complex binding;GO:0140297 DNA-binding transcription factor binding", "go_cellular_component": "GO:0000922 spindle pole;GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0016202 regulation of striated muscle tissue development;GO:0051310 metaphase chromosome alignment;GO:0000278 mitotic cell cycle;GO:0007059 chromosome segregation;GO:0015031 protein transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "E9PT83-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E9PT91-1", "uniprot_id": "E9PT91_RAT", "mass": 67310.0, "length": 596, "protein_name": "Alpha-1,3-glucosyltransferase", "gene_name": "Alg8", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Alg8", "gene_names_refseq": "", "protein_names_uniprotkb": "Alpha-1,3-glucosyltransferase; 2.4.1.-", "protein_names_refseq": "", "tax_id": 10116, "disease": "congenital disorder of glycosylation type I (Disease Ontology:DOID:0050570); polycystic liver disease 3 (Disease Ontology:DOID:0060976); congenital disorder of glycosylation Ih (Disease Ontology:DOID:0080560)", "pathway": " (R-RNO-446193)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.1.-", "go_molecular_function": "GO:0042283 dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006488 dolichol-linked oligosaccharide biosynthetic process;GO:0006487 protein N-linked glycosylation", "synthesized_glycan_count": 81, "hit_score": 0.1, "record_id": "E9PT91-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E9PTF3-1", "uniprot_id": "E9PTF3_RAT", "mass": 85753.0, "length": 748, "protein_name": "NOC2-like nucleolar associated transcriptional repressor", "gene_name": "Noc2l", "organism": "Rat", "refseq_name": "nucleolar complex protein 2 homolog isoform 1", "refseq_ac": "NP_001386120", "gene_names_uniprotkb": "Noc2l", "gene_names_refseq": "Noc2l; RGD1309387", "protein_names_uniprotkb": "NOC2-like nucleolar associated transcriptional repressor", "protein_names_refseq": "nucleolar complex protein 2 homolog isoform 1; nucleolar complex protein 2 homolog", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-6804756)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0003714 transcription corepressor activity;GO:0042393 histone binding;GO:0031491 nucleosome binding;GO:0140297 DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005694 chromosome;GO:0030690 Noc1p-Noc2p complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0042273 ribosomal large subunit biogenesis;GO:0045815 transcription initiation-coupled chromatin remodeling;GO:0034644 cellular response to UV;GO:2001243 negative regulation of intrinsic apoptotic signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "E9PTF3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E9PTG0-1", "uniprot_id": "E9PTG0_RAT", "mass": 100021.0, "length": 889, "protein_name": "Zinc finger with KRAB and SCAN domains 7", "gene_name": "Zkscan7", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Zkscan7; Zfp167", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger with KRAB and SCAN domains 7", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:363170); (R-RNO-212436)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E9PTG0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E9PTN6-1", "uniprot_id": "E9PTN6_RAT", "mass": 36015.0, "length": 333, "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "LOC108352348", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LOC108352348; AABR07034445.1", "gene_names_refseq": "", "protein_names_uniprotkb": "Glyceraldehyde-3-phosphate dehydrogenase; 1.2.1.12", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.2.1.12;2.6.99.-", "go_molecular_function": "GO:0051287 NAD binding;GO:0016740 transferase activity;GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity;GO:0050661 NADP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005856 cytoskeleton", "go_biological_process": "GO:0006417 regulation of translation;GO:0045087 innate immune response;GO:0006915 apoptotic process;GO:0006094 gluconeogenesis;GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E9PTN6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E9PTT8-1", "uniprot_id": "E9PTT8_RAT", "mass": 32428.0, "length": 281, "protein_name": "Cysteine-rich secretory protein 1", "gene_name": "Crisp1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Crisp1", "gene_names_refseq": "", "protein_names_uniprotkb": "Cysteine-rich secretory protein 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005246 calcium channel regulator activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007339 binding of sperm to zona pellucida;GO:0060046 regulation of acrosome reaction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E9PTT8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E9PTY1-1", "uniprot_id": "E9PTY1_RAT", "mass": 33633.0, "length": 309, "protein_name": "Opiorphin prepropeptide", "gene_name": "Oprpn", "organism": "Rat", "refseq_name": "opiorphin prepropeptide precursor", "refseq_ac": "NP_598197", "gene_names_uniprotkb": "Oprpn; Prol1", "gene_names_refseq": "Muc10; Oprpn; Prol1; RSM-1", "protein_names_uniprotkb": "Opiorphin prepropeptide", "protein_names_refseq": "mucin 10, submandibular gland salivary mucin; opiorphin prepropeptide precursor; proline rich, lacrimal 1", "tax_id": 10116, "disease": "", "pathway": " (rno:65182)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "24486428", "class_list": "", "function": "Opiorphin may play an important role in the modulation of blood pressure through angiotensin II dependent pathways, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030414 peptidase inhibitor activity;GO:0004866 endopeptidase inhibitor activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0051930 regulation of sensory perception of pain", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "E9PTY1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E9PU00-1", "uniprot_id": "E9PU00_RAT", "mass": 90573.0, "length": 791, "protein_name": "Transient receptor potential cation channel subfamily V member 3", "gene_name": "Trpv3", "organism": "Rat", "refseq_name": "transient receptor potential cation channel subfamily V member 3", "refseq_ac": "NP_001020928", "gene_names_uniprotkb": "Trpv3", "gene_names_refseq": "Trpv3", "protein_names_uniprotkb": "Transient receptor potential cation channel subfamily V member 3", "protein_names_refseq": "heat sensitive channel TRPV3; transient receptor potential cation channel subfamily V member 3", "tax_id": 10116, "disease": "congenital stationary night blindness (Disease Ontology:DOID:0050534); focal nonepidermolytic palmoplantar keratoderma 2 (Disease Ontology:DOID:0111711); autosomal dominant mutilating palmoplantar keratoderma with periorificial keratotic plaques (Disease Ontology:DOID:0112013); migraine with aura (Disease Ontology:DOID:10024); dermatitis (Disease Ontology:DOID:2723); atopic dermatitis (Disease Ontology:DOID:3310); schizophrenia (Disease Ontology:DOID:5419); rosacea (Disease Ontology:DOID:8881); colorectal cancer (Disease Ontology:DOID:9256); alopecia (Disease Ontology:DOID:987)", "pathway": " (rno:497948); (R-RNO-3295583)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "15653710;16858425;29359496;30299584;30488220;30604587;31706959", "class_list": "", "function": "Activation of the peripheral ion channel TRPM8 with menthol and rapid cooling (decrease in body temperature by 3C) led to 1.5-fold activation of the expression of TRPV3 ion channel gene in the posterior hypothalamus, but had no effect on the expression of this gene in the anterior hypothalamus., [RefSeq, PubMed]; MiR-103 could attenuate cardiomyocyte hypertrophy partly by reducing cardiac autophagy activity through the targeted inhibition of TRPV3 signalling., [RefSeq, PubMed]; Non-selective calcium permeant cation channel. It is activated by innocuous (warm) temperatures and shows an increased response at noxious temperatures greater than 39 degrees Celsius. Activation exhibits an outward rectification. The channel pore can dilate to provide permeability to larger cations. May associate with TRPV1 and may modulate its activity. Is a negative regulator of hair growth and cycling: TRPV3-coupled signaling suppresses keratinocyte proliferation in hair follicles and induces apoptosis and premature hair follicle regression (catagen)., [UniProtKB, UniProtKB]; TRPV1, V2, and V3 channels are expressed on these sensory neurons and their terminals., [RefSeq, PubMed]; TRPV3 is involved in hypoxia-induced pulmonary vascular remodeling and promotes proliferation of pulmonary artery smooth muscle cells and the effect is, at least in part, mediated via the PI3K/AKT pathway., [RefSeq, PubMed]; TRPV3 was the gene responsible for Nh and Ht mutations, and mutation in TRPV3 possibly correlated with increased mast cell numbers., [RefSeq, PubMed]; The activation of TRPV3 aggravated pathological cardiac hypertrophy through calcineurin/NFATc3 signalling pathway and correlated with the protein expression levels of calcineurin, phosphorylated CaMKII and NFATc3, revealing that TRPV3 might be a potential therapeutic target for cardiac hypertrophy., [RefSeq, PubMed]; Transient Receptor Potential Vanilloid 3 (TRPV3) in the Cerebellum of Rat and Its Role in Motor Coordination., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;1.8.-.-", "go_molecular_function": "GO:0005216 monoatomic ion channel activity;GO:0005262 calcium channel activity;GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0005261 monoatomic cation channel activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005929 cilium;GO:0016020 membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0007231 osmosensory signaling pathway;GO:0007015 actin filament organization;GO:0009266 response to temperature stimulus;GO:0090280 positive regulation of calcium ion import;GO:0098703 calcium ion import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "E9PU00-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E9PU04-1", "uniprot_id": "E9PU04_RAT", "mass": 26403.0, "length": 233, "protein_name": "Transmembrane protein 179", "gene_name": "Tmem179", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Tmem179", "gene_names_refseq": "", "protein_names_uniprotkb": "Transmembrane protein 179", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E9PU04-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E9PU34-1", "uniprot_id": "E9PU34_RAT", "mass": 51699.0, "length": 450, "protein_name": "Required for meiotic nuclear division 1 homolog", "gene_name": "Rmnd1", "organism": "Rat", "refseq_name": "required for meiotic nuclear division protein 1 homolog", "refseq_ac": "NP_001035217", "gene_names_uniprotkb": "Rmnd1", "gene_names_refseq": "Iag-1; RGD1309546; Rmnd1", "protein_names_uniprotkb": "Required for meiotic nuclear division 1 homolog", "protein_names_refseq": "implantation-associated gene-1; required for meiotic nuclear division protein 1 homolog", "tax_id": 10116, "disease": "combined oxidative phosphorylation deficiency 11 (Disease Ontology:DOID:0111481)", "pathway": " (rno:292268)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "18296448;36690096", "class_list": "", "function": "Fluoride impairs mitochondrial translation by targeting miR-221-3p/c-Fos/RMND1 axis contributing to neurodevelopment defects., [RefSeq, PubMed]; Overexpression of Iag-1 can inhibit endometrial stromal cell proliferation and induce endometrial stroma cells apoptosis, and p53 and Bax may play an important role in the process of Iag-1-induced apoptosis., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0070131 positive regulation of mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "E9PU34-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E9PU35-1", "uniprot_id": "E9PU35_RAT", "mass": 9779.0, "length": 86, "protein_name": "Serine peptidase inhibitor, Kazal type 4", "gene_name": "Spink4", "organism": "Rat", "refseq_name": "serine protease inhibitor Kazal-type 4 precursor", "refseq_ac": "NP_001382679", "gene_names_uniprotkb": "Spink4", "gene_names_refseq": "PEC-60; Spink4", "protein_names_uniprotkb": "Serine peptidase inhibitor, Kazal type 4", "protein_names_refseq": "Kazal type serine protease inhibitor 4; serine protease inhibitor Kazal-type 4 precursor; serine protease inhibitor Kazal-type 4", "tax_id": 10116, "disease": "", "pathway": " (rno:408233)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0009410 response to xenobiotic stimulus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E9PU35-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E9PU64-1", "uniprot_id": "E9PU64_RAT", "mass": 75361.0, "length": 671, "protein_name": "Scinderin", "gene_name": "Scin", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Scin", "gene_names_refseq": "", "protein_names_uniprotkb": "Scinderin; Adseverin", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:298975)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16641100", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005903 brush border;GO:0015629 actin cytoskeleton;GO:0002102 podosome;GO:0032991 protein-containing complex", "go_biological_process": "GO:0008285 negative regulation of cell population proliferation;GO:0043065 positive regulation of apoptotic process;GO:0007417 central nervous system development;GO:0051016 barbed-end actin filament capping;GO:0008154 actin polymerization or depolymerization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "E9PU64-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E9PU86-1", "uniprot_id": "E9PU86_RAT", "mass": 72263.0, "length": 684, "protein_name": "POU domain protein", "gene_name": "AABR07027925.1; Pou6f2", "organism": "Rat", "refseq_name": "POU domain, class 6, transcription factor 2", "refseq_ac": "NP_001094472", "gene_names_uniprotkb": "AABR07027925.1; Pou6f2; AABR07027925.1; Pou6f2", "gene_names_refseq": "Pou6f2", "protein_names_uniprotkb": "POU domain protein", "protein_names_refseq": "POU domain, class 6, transcription factor 2; retina-derived POU-domain factor 1", "tax_id": 10116, "disease": "", "pathway": " (rno:681092)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "24804940", "class_list": "", "function": "Expressed in the stem/progenitor cells of the rat pituitary primordium as well as the diencephalon and retina, [RefSeq, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "A0A097ZIC4", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "E9PU86-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LMA9-1", "uniprot_id": "F1LMA9_RAT", "mass": 218656.0, "length": 1907, "protein_name": "NFX1-type zinc finger-containing protein 1", "gene_name": "Znfx1", "organism": "Rat", "refseq_name": "NFX1-type zinc finger-containing protein 1", "refseq_ac": "NP_001376200", "gene_names_uniprotkb": "Znfx1", "gene_names_refseq": "Ab1-133; RGD1306344; Znfx1", "protein_names_uniprotkb": "NFX1-type zinc finger-containing protein 1", "protein_names_refseq": "NFX1-type zinc finger-containing protein 1", "tax_id": 10116, "disease": "immunodeficiency 91 (Disease Ontology:DOID:0061061)", "pathway": " (rno:296384)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "28295592", "class_list": "", "function": "Knockdown of ZFAS1 or miR-150 overexpression effectively relieved AMI-induced myocardial infarction in AMI-1 week rats. The ZFAS1/miR-150 axis was involved in the molecular mechanism of AMI induced cardiomyocytes apoptosis via regulating CRP, [RefSeq, PubMed]; RNA-binding protein that initiates the antiviral response and is required to restrict the replication of RNA viruses. Acts as a double-stranded RNA (dsRNA) sensor that recognizes viral RNA and then interacts with MAVS to initiate the type I interferon response. Also required for immunity against some bacteria, such as mycobacteria., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0008270 zinc ion binding;GO:0004386 helicase activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0010494 cytoplasmic stress granule;GO:0031380 nuclear RNA-directed RNA polymerase complex;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0045087 innate immune response;GO:0051607 defense response to virus;GO:0031048 regulatory ncRNA-mediated heterochromatin formation;GO:0045071 negative regulation of viral genome replication;GO:0042742 defense response to bacterium", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1LMA9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LML7-1", "uniprot_id": "F1LML7_RAT", "mass": 119939.0, "length": 1073, "protein_name": "Huntingtin-interacting protein 1-related protein", "gene_name": "Hip1r", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Hip1r", "gene_names_refseq": "", "protein_names_uniprotkb": "Huntingtin-interacting protein 1-related protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:81917); (R-RNO-432722); (R-RNO-8856828)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding;GO:0017124 SH3 domain binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0005905 clathrin-coated pit", "go_biological_process": "GO:0060453 regulation of gastric acid secretion;GO:1905445 positive regulation of clathrin coat assembly;GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway;GO:0006897 endocytosis;GO:0007015 actin filament organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LML7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LMV6-1", "uniprot_id": "DESP_RAT", "mass": 332393.0, "length": 2877, "protein_name": "Desmoplakin", "gene_name": "Dsp", "organism": "Rat", "refseq_name": "desmoplakin", "refseq_ac": "NP_001406527", "gene_names_uniprotkb": "Dsp", "gene_names_refseq": "DP; Dsp", "protein_names_uniprotkb": "Desmoplakin; DP", "protein_names_refseq": "desmoplakin", "tax_id": 10116, "disease": "arrhythmogenic right ventricular cardiomyopathy (Disease Ontology:DOID:0050431); keratosis palmoplantaris striata 2 (Disease Ontology:DOID:0081109); Carvajal syndrome (Disease Ontology:DOID:0090128); arrhythmogenic right ventricular dysplasia 8 (Disease Ontology:DOID:0110076); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); dilated cardiomyopathy (Disease Ontology:DOID:12930)", "pathway": " (rno:306871); (R-RNO-351906); (R-RNO-6798695); (R-RNO-6805567); (R-RNO-6809371); (R-RNO-9696264); (R-RNO-9696273)", "pathway_count": 7, "publication_count": 7, "publication_id_list": "11125272;16396499;22673903;25225338;26858265;29959233;34502162", "class_list": "", "function": "A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion (By similarity). Critical for cell-cell adhesion in early stage blastocysts and progression through proamniotic cavity formation (By similarity). Not required for preimplantation morphogenic process in blastocysts (By similarity). Required for keratin filament anchoring at the desmosome junction and subsequent organization of the keratin intermediate filament network within the cytoplasm (By similarity). Required for anchoring of desmosomes to the microtubule architecture, via its interaction with NIN (By similarity). Promotes microtubule-mediated GJA1/CX43 trafficking to cell membranes via its interaction with MAPRE1/EB1, thereby facilitating gap junction intracellular communication (PubMed:25225338). Plays a key role in adhesion and organization of the dermal epithelial barrier (By similarity). Critical for the maintenance of the neural tube structure following formation and organization of the neuroepithelium (By similarity). Facilitates outgrowth and repair of motor neuron fibers in regenerating axons following injury, probably by promoting recruitment of a complex containing DSP, CDH2, VIM and JUP to the outgrowth tips (By similarity). Critical for the normal formation of heart and myocardial tissue during early embryogenesis (By similarity). Also required for development of vascular capillary structures and intact endothelial cell barriers (By similarity). Regulates profibrotic gene expression in cardiomyocytes via activation of the MAPK14/p38 MAPK signaling cascade and increase in TGFB1 protein abundance (PubMed:26858265). Maintains cardiac rhythmicity by ensuring correct cell-cell adhesion within the sinoatrial node, via stabilization of protein components of both desmosome and Gap junctions (By similarity). Involved in maintaining the protein stability and recruitment of GJA1 to functional gap junctions, via inhibition of KRAS-mediated MAPK1/MAPK3 phosphorylation of GJA1 (By similarity). Negative regulator of cell cycle progression and differentiation in keratinocytes, potentially via inhibition of MAPK and phosphoinositide-3-kinase (PI3K) signaling pathways (By similarity). Mediates the interaction between the desmosome and COP9 signalosome complex (CSN) protein complex (By similarity). As a result of this interaction, promotes keratinocyte differentiation via deneddylation of EGFR resulting in a reduction in EGFR protein stabilization and translocation away from the cell membrane (By similarity). Required for the maintenance of protein abundance of desmosome junction components DSG1, DSG2, DSC2, DSC3, PKP1, PKP2 and PKP3 (By similarity). Required for the survival and maintenance of germ cells in the gonads during embryonic development (By similarity). Binds to telomere DNA (via C-terminus) and acts to prevent telomere damage and maintain telomere length via its interaction with TRF2 (By similarity)., [UniProtKB, PubMed, UniProtKB, UniProtKB, PubMed]; Desmoplakin prevents lysosomal-mediated degradation of Cx43. Desmoplakin loss triggered robust activation of ERK1/2-MAPK and increased phosphorylation of S279/282 of Cx43, which signals clathrin-mediated internalization and subsequent lysosomal degradation of Cx43., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 28, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q4QQR7", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0005080 protein kinase C binding;GO:0005198 structural molecule activity;GO:0097110 scaffold protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005911 cell-cell junction;GO:0005912 adherens junction", "go_biological_process": "GO:0150105 protein localization to cell-cell junction;GO:0086091 regulation of heart rate by cardiac conduction;GO:0030216 keratinocyte differentiation;GO:0098609 cell-cell adhesion;GO:0018149 peptide cross-linking", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "F1LMV6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LN81-1", "uniprot_id": "F1LN81_RAT", "mass": 87277.0, "length": 814, "protein_name": "ATM interactor", "gene_name": "AABR07043951.1; Atmin", "organism": "Rat", "refseq_name": "ATM interactor", "refseq_ac": "NP_001178715", "gene_names_uniprotkb": "AABR07043951.1; Atmin; AABR07043951.1; Atmin", "gene_names_refseq": "Asciz; Atmin; RGD1305781", "protein_names_uniprotkb": "ATM interactor", "protein_names_refseq": "ATM interactor; ATM/ATR-Substrate Chk2-Interacting Zn2+-finger protein", "tax_id": 10116, "disease": "", "pathway": " (rno:315037)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000976 transcription cis-regulatory region binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0070840 dynein complex binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0016604 nuclear body", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0010628 positive regulation of gene expression;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription;GO:0044458 motile cilium assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LN81-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LN97-1", "uniprot_id": "F1LN97_RAT", "mass": 36952.0, "length": 343, "protein_name": "ALX homeobox 3", "gene_name": "Alx3", "organism": "Rat", "refseq_name": "homeobox protein aristaless-like 3", "refseq_ac": "NP_001007013", "gene_names_uniprotkb": "Alx3", "gene_names_refseq": "Alx3", "protein_names_uniprotkb": "ALX homeobox 3", "protein_names_refseq": "aristaless 3; aristaless-like homeobox 3; homeobox protein aristaless-like 3", "tax_id": 10116, "disease": "frontonasal dysplasia 1 (Disease Ontology:DOID:0081045)", "pathway": " (rno:365900)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15226305", "class_list": "", "function": "Alx3 undergoes restrictive or permissive interactions with nuclear proteins that determine its binding to and transactivation from TAAT target sites selected in a cell-specific manner, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:1990837 sequence-specific double-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0035115 embryonic forelimb morphogenesis;GO:0042981 regulation of apoptotic process;GO:0035116 embryonic hindlimb morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1LN97-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LP88-1", "uniprot_id": "F1LP88_RAT", "mass": 29860.0, "length": 266, "protein_name": "Uncharacterized protein", "gene_name": "", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LP88-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LPT0-1", "uniprot_id": "F1LPT0_RAT", "mass": 28876.0, "length": 257, "protein_name": "Gap junction protein", "gene_name": "Gjc3", "organism": "Rat", "refseq_name": "gap junction gamma-3 protein", "refseq_ac": "XP_221997", "gene_names_uniprotkb": "Gjc3", "gene_names_refseq": "Gjc3", "protein_names_uniprotkb": "Gap junction protein", "protein_names_refseq": "gap junction gamma-3 protein", "tax_id": 10116, "disease": "", "pathway": " (rno:288529)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Structural component of the gap junction, a specialized intercellular structure consisting of a cluster of closely packed pairs of transmembrane channels, the connexons, that allow passage of small molecules and electrical signals between neighboring cells. Forms homotypic and heterotypic channels gated by transjunctional voltage. Involved in intercellular innate immune signaling. Mediates translocation of 2',3'-cGAMP and 2',5'-oligoadenylates (2-5A) second messengers from virus-infected cells to macrophages and uninfected neighboring cells to propagate and amplify the antiviral immune response., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A654IDW2;A0A8I5ZPD7", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding", "go_cellular_component": "GO:0043209 myelin sheath;GO:0005922 connexin complex", "go_biological_process": "GO:0042552 myelination;GO:0007605 sensory perception of sound;GO:0007154 cell communication", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1LPT0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LQB4-1", "uniprot_id": "F1LQB4_RAT", "mass": 47419.0, "length": 413, "protein_name": "Palmitoyltransferase", "gene_name": "Zdhhc6", "organism": "Rat", "refseq_name": "palmitoyltransferase ZDHHC6", "refseq_ac": "NP_001032741", "gene_names_uniprotkb": "Zdhhc6", "gene_names_refseq": "Zdhhc6", "protein_names_uniprotkb": "Palmitoyltransferase; 2.3.1.225", "protein_names_refseq": "membrane-associated DHHC6 zinc finger protein; palmitoyltransferase ZDHHC6; probable palmitoyltransferase ZDHHC6; zinc finger DHHC-type palmitoyltransferase 6; zinc finger, DHHC domain containing 6; zinc finger, DHHC-type containing 6", "tax_id": 10116, "disease": "", "pathway": " (rno:361771)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.1.225;2.3.1.-;6.3.1.2", "go_molecular_function": "GO:0019706 protein-cysteine S-palmitoyltransferase activity;GO:0016409 palmitoyltransferase activity;GO:0140439 protein-cysteine S-stearoyltransferase activity", "go_cellular_component": "GO:0016020 membrane;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0006612 protein targeting to membrane;GO:0035556 intracellular signal transduction;GO:0018345 protein palmitoylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LQB4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LQV2-1", "uniprot_id": "F1LQV2_RAT", "mass": 72542.0, "length": 660, "protein_name": "Solute carrier family 5 (neutral amino acid transporters, system A), member 4b", "gene_name": "Slc5a4b", "organism": "Rat", "refseq_name": "solute carrier family 5 member 4", "refseq_ac": "XP_008771154", "gene_names_uniprotkb": "Slc5a4b", "gene_names_refseq": "Slc5a4b", "protein_names_uniprotkb": "Solute carrier family 5 (neutral amino acid transporters, system A), member 4b", "protein_names_refseq": "solute carrier family 5 member 4", "tax_id": 10116, "disease": "", "pathway": " (rno:294342)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005362 low-affinity D-glucose:sodium symporter activity;GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0035623 renal D-glucose absorption;GO:0098708 D-glucose import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LQV2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LRC7-1", "uniprot_id": "F1LRC7_RAT", "mass": 225379.0, "length": 2087, "protein_name": "Bromodomain containing 10", "gene_name": "Brd10", "organism": "Rat", "refseq_name": "uncharacterized protein KIAA2026 homolog", "refseq_ac": "NP_001406391", "gene_names_uniprotkb": "Brd10; RGD1311595", "gene_names_refseq": "Brd10; Kiaa2026; RGD1311595", "protein_names_uniprotkb": "Bromodomain containing 10", "protein_names_refseq": "uncharacterized protein KIAA2026 homolog", "tax_id": 10116, "disease": "", "pathway": " (rno:309307)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LRC7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LRH7-1", "uniprot_id": "F1LRH7_RAT", "mass": 97740.0, "length": 869, "protein_name": "Interleukin-12 receptor subunit beta-2", "gene_name": "Il12rb2", "organism": "Rat", "refseq_name": "interleukin-12 receptor subunit beta-2 precursor", "refseq_ac": "NP_001178679", "gene_names_uniprotkb": "Il12rb2", "gene_names_refseq": "Il12rb2", "protein_names_uniprotkb": "Interleukin-12 receptor subunit beta-2", "protein_names_refseq": "interleukin 12 receptor, beta 2; interleukin-12 receptor subunit beta-2 precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:171334); (R-RNO-8984722); (R-RNO-9020591)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015026 coreceptor activity;GO:0019901 protein kinase binding;GO:0019955 cytokine binding;GO:0004896 cytokine receptor activity", "go_cellular_component": "GO:0043235 receptor complex;GO:0009897 external side of plasma membrane;GO:0042022 interleukin-12 receptor complex;GO:0005886 plasma membrane", "go_biological_process": "GO:0051142 positive regulation of NK T cell proliferation;GO:0045622 regulation of T-helper cell differentiation;GO:0008284 positive regulation of cell population proliferation;GO:0018108 peptidyl-tyrosine phosphorylation;GO:0032496 response to lipopolysaccharide", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LRH7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LRX2-1", "uniprot_id": "F1LRX2_RAT", "mass": 176714.0, "length": 1586, "protein_name": "Formin homology 2 domain containing 3", "gene_name": "Fhod3", "organism": "Rat", "refseq_name": "FH1/FH2 domain-containing protein 3 isoform 4", "refseq_ac": "NP_001402649", "gene_names_uniprotkb": "Fhod3", "gene_names_refseq": "Fhod3", "protein_names_uniprotkb": "Formin homology 2 domain containing 3", "protein_names_refseq": "FH1/FH2 domain-containing protein 3 isoform 4; FH1/FH2 domain-containing protein 3", "tax_id": 10116, "disease": "familial hypertrophic cardiomyopathy (Disease Ontology:DOID:0080326)", "pathway": " (rno:100360334)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "19706596;23052206;24088304;26912794", "class_list": "", "function": "Actin dynamics regulated by Fhod3 are critical for sarcomere organization in striated muscle cells., [RefSeq, PubMed]; DCM-associated FHOD3 variant may cause DCM by interfering with actin filament assembly., [RefSeq, PubMed]; FHOD3 played a role in glioma linear migration., [RefSeq, PubMed]; Following myofibril disassembly, such as that in dedifferentiating adult rat cardiomyocytes in culture, the expression of non-muscle Fhod3 is up-regulated, which is reversed once the myofibrils are reassembled., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051015 actin filament binding;GO:0003779 actin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0030017 sarcomere;GO:0005865 striated muscle thin filament", "go_biological_process": "GO:0007015 actin filament organization;GO:0051496 positive regulation of stress fiber assembly;GO:0055003 cardiac myofibril assembly;GO:0045214 sarcomere organization;GO:0051639 actin filament network formation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "F1LRX2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LRZ9-1", "uniprot_id": "F1LRZ9_RAT", "mass": 46740.0, "length": 413, "protein_name": "RUN domain-containing protein 3A", "gene_name": "Rundc3a", "organism": "Rat", "refseq_name": "RUN domain-containing protein 3A isoform X6", "refseq_ac": "XP_017452813", "gene_names_uniprotkb": "Rundc3a", "gene_names_refseq": "GCRP; Rap2ip; Rundc3a", "protein_names_uniprotkb": "RUN domain-containing protein 3A", "protein_names_refseq": "RUN domain-containing protein 3A isoform X6", "tax_id": 10116, "disease": "", "pathway": " (rno:303569)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "May act as an effector of RAP2A in neuronal cells., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0046068 cGMP metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1LRZ9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LS62-1", "uniprot_id": "F1LS62_RAT", "mass": 120130.0, "length": 1053, "protein_name": "[histone H3]-trimethyl-L-lysine(9) demethylase", "gene_name": "Kdm4c", "organism": "Rat", "refseq_name": "lysine-specific demethylase 4C", "refseq_ac": "NP_001100133", "gene_names_uniprotkb": "Kdm4c", "gene_names_refseq": "Jmjd2c; Kdm4c", "protein_names_uniprotkb": "[histone H3]-trimethyl-L-lysine(9) demethylase; 1.14.11.66", "protein_names_refseq": "jumonji domain containing 2C; lysine (K)-specific demethylase 4C; lysine-specific demethylase 4C-like; lysine-specific demethylase 4C", "tax_id": 10116, "disease": "medulloblastoma (Disease Ontology:DOID:0050902); withdrawal disorder (Disease Ontology:DOID:0060001); prostate cancer (Disease Ontology:DOID:10283); head and neck cancer (Disease Ontology:DOID:11934); autistic disorder (Disease Ontology:DOID:12849); alcohol use disorder (Disease Ontology:DOID:1574); breast cancer (Disease Ontology:DOID:1612); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); renal cell carcinoma (Disease Ontology:DOID:4450); stomach carcinoma (Disease Ontology:DOID:5517); alopecia areata (Disease Ontology:DOID:986)", "pathway": " (rno:298144); (R-RNO-3214842); (R-RNO-5625886)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "24747049;34121556", "class_list": "", "function": "Data indicate that histone demethylases KDM4A/C regulate H3K9 and H3K36 methylation on brain-derived neurotrophic factor (BDNF) versus astroglial glial fibrillary acidic protein (GFAP) genes in neural stem cells., [RefSeq, PubMed]; MicroRNA-340-5p inhibits endothelial apoptosis, inflammatory response, and pro-coagulation by targeting KDM4C in anti-neutrophil cytoplasmic antibody (ANCA)-mediated glomerulonephritis through activation of B cells., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 11, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.14.11.69;1.14.11.66;2.7.11.13;1.14.11.-;1.14.11.79", "go_molecular_function": "GO:0051864 histone H3K36 demethylase activity;GO:0008270 zinc ion binding;GO:0032454 histone H3K9 demethylase activity;GO:0140684 histone H3K9me2/H3K9me3 demethylase activity;GO:0003682 chromatin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0005721 pericentric heterochromatin", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0010468 regulation of gene expression;GO:0008284 positive regulation of cell population proliferation;GO:0010628 positive regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1LS62-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LSM0-1", "uniprot_id": "F1LSM0_RAT", "mass": 294034.0, "length": 2617, "protein_name": "Ubiquitin carboxyl-terminal hydrolase 24", "gene_name": "Usp24", "organism": "Rat", "refseq_name": "ubiquitin carboxyl-terminal hydrolase 24", "refseq_ac": "NP_001258135", "gene_names_uniprotkb": "Usp24", "gene_names_refseq": "Usp24", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase 24; 3.4.19.12; Deubiquitinating enzyme 24; Ubiquitin thioesterase 24; Ubiquitin-specific-processing protease 24", "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase 24; ubiquitin specific protease 24", "tax_id": 10116, "disease": "", "pathway": " (rno:313427); (R-RNO-5689880)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.4.19.12", "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006508 proteolysis;GO:0016579 protein deubiquitination;GO:0031647 regulation of protein stability", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1LSM0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LSP9-1", "uniprot_id": "F1LSP9_RAT", "mass": 63539.0, "length": 582, "protein_name": "FGGY carbohydrate kinase domain-containing protein", "gene_name": "Fggy", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Fggy", "gene_names_refseq": "", "protein_names_uniprotkb": "FGGY carbohydrate kinase domain-containing protein; 2.7.1.47; D-ribulokinase FGGY", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes ATP-dependent phosphorylation of D-ribulose at C-5 to form D-ribulose 5-phosphate. Postulated to function in a metabolite repair mechanism by preventing toxic accumulation of free D-ribulose formed by non-specific phosphatase activities. Alternatively, may play a role in regulating D-ribulose 5-phosphate recycling in the pentose phosphate pathway. Can phosphorylate ribitol with low efficiency., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.1.47", "go_molecular_function": "GO:0019150 D-ribulokinase activity;GO:0016301 kinase activity;GO:0016773 phosphotransferase activity, alcohol group as acceptor", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0070050 neuron cellular homeostasis;GO:0019321 pentose metabolic process;GO:0046835 carbohydrate phosphorylation;GO:0005975 carbohydrate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LSP9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LSU5-1", "uniprot_id": "F1LSU5_RAT", "mass": 9878.0, "length": 90, "protein_name": "Defensin alpha 31", "gene_name": "Defa31", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Defa31; Defa10", "gene_names_refseq": "", "protein_names_uniprotkb": "Defensin alpha 31", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-1461973); (R-RNO-1462054); (R-RNO-6798695)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0140911 pore-forming activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0019731 antibacterial humoral response;GO:0045087 innate immune response;GO:0050829 defense response to Gram-negative bacterium;GO:0050830 defense response to Gram-positive bacterium;GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LSU5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LSX1-1", "uniprot_id": "F1LSX1_RAT", "mass": 254235.0, "length": 2234, "protein_name": "Ribosomal protein S6 kinase related", "gene_name": "Bltp2; Rskr", "organism": "Rat", "refseq_name": "bridge-like lipid transfer protein family member 2", "refseq_ac": "NP_001414015", "gene_names_uniprotkb": "Bltp2; Rskr; RGD1307929; Rskr", "gene_names_refseq": "Bltp2; RGD1307929", "protein_names_uniprotkb": "Ribosomal protein S6 kinase related", "protein_names_refseq": "bridge-like lipid transfer protein family member 2", "tax_id": 10116, "disease": "", "pathway": " (rno:120093092)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LSX1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LT49-1", "uniprot_id": "F1LT49_RAT", "mass": 65822.0, "length": 601, "protein_name": "Leucine-rich repeat-containing protein 47", "gene_name": "Lrrc47", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Lrrc47", "gene_names_refseq": "", "protein_names_uniprotkb": "Leucine-rich repeat-containing protein 47", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:362672)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "16641100;22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0004826 phenylalanine-tRNA ligase activity", "go_cellular_component": "", "go_biological_process": "GO:0006432 phenylalanyl-tRNA aminoacylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1LT49-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LT76-1", "uniprot_id": "F1LT76_RAT", "mass": 70797.0, "length": 608, "protein_name": "Zinc finger protein 950 like 8", "gene_name": "Zfp950", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Zfp950; Zfp80; Zfp950l8", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger protein 950 like 8", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0001570 vasculogenesis;GO:0006357 regulation of transcription by RNA polymerase II;GO:0001822 kidney development;GO:0014909 smooth muscle cell migration;GO:0035264 multicellular organism growth", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LT76-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LTK3-1", "uniprot_id": "F1LTK3_RAT", "mass": 36338.0, "length": 324, "protein_name": "Olfactory receptor", "gene_name": "Or10a49", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Or10a49", "gene_names_refseq": "", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LTK3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LTW8-1", "uniprot_id": "F1LTW8_RAT", "mass": 15821.0, "length": 143, "protein_name": "Small ribosomal subunit protein uS12", "gene_name": "Rps23-ps11", "organism": "Rat", "refseq_name": "small ribosomal subunit protein uS12-like", "refseq_ac": "XP_038938807", "gene_names_uniprotkb": "Rps23-ps11; 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The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds to G-rich structures in 28S rRNA and in mRNAs. 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Binds to EFNA3, EFNA4 and EFNA5., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, 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"Adam1b", "protein_names_uniprotkb": "A disintegrin and metallopeptidase domain 1b", "protein_names_refseq": "disintegrin and metalloproteinase domain-containing protein 1b; rCG21419-like", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, 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"F1LXM2_RAT", "mass": 157998.0, "length": 1434, "protein_name": "Similar to human chromosome 4 open reading frame 50", "gene_name": "C14h4orf50", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "C14h4orf50; LOC102553825", "gene_names_refseq": "", "protein_names_uniprotkb": "Similar to human chromosome 4 open reading frame 50", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LXM2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LXT9-1", "uniprot_id": "F1LXT9_RAT", "mass": 36787.0, "length": 333, "protein_name": "Membrane cofactor protein", "gene_name": "Cd46l1", "organism": "Rat", "refseq_name": "membrane cofactor protein-like", "refseq_ac": "XP_006256563", "gene_names_uniprotkb": "Cd46l1; RGD1559810", "gene_names_refseq": "Cd46l1", "protein_names_uniprotkb": "Membrane cofactor protein", "protein_names_refseq": "membrane cofactor protein-like", "tax_id": 10116, "disease": "meningococcal meningitis (Disease Ontology:DOID:0080176); atypical hemolytic-uremic syndrome (Disease Ontology:DOID:0080301); pre-eclampsia (Disease Ontology:DOID:10591); hemolytic-uremic syndrome (Disease Ontology:DOID:12554); multiple sclerosis (Disease Ontology:DOID:2377); thrombophilia (Disease Ontology:DOID:2452); contact dermatitis (Disease Ontology:DOID:2773); breast carcinoma (Disease Ontology:DOID:3459); renal cell carcinoma (Disease Ontology:DOID:4450); cervix uteri carcinoma in situ (Disease Ontology:DOID:8991); systemic lupus erythematosus (Disease Ontology:DOID:9074); viral infectious disease (Disease Ontology:DOID:934); bacterial meningitis (Disease Ontology:DOID:9470); multiple myeloma (Disease Ontology:DOID:9538); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (rno:365577)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in the fusion of the spermatozoa with the oocyte during fertilization., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 15, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0002079 inner acrosomal membrane", "go_biological_process": "GO:0007338 single fertilization;GO:0045959 negative regulation of complement activation, classical pathway;GO:0002456 T cell mediated immunity", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LXT9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LY16-1", "uniprot_id": "F1LY16_RAT", "mass": 261091.0, "length": 2327, "protein_name": "Otogelin-like", "gene_name": "Otogl", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Otogl", "gene_names_refseq": "", "protein_names_uniprotkb": "Otogelin-like", "protein_names_refseq": "", "tax_id": 10116, "disease": "autosomal recessive nonsyndromic deafness 84B (Disease Ontology:DOID:0110530)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005201 extracellular matrix structural constituent;GO:0046556 alpha-L-arabinofuranosidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix;GO:0005576 extracellular region", "go_biological_process": "GO:0007605 sensory perception of sound;GO:0008104 intracellular protein localization;GO:0060122 inner ear receptor cell stereocilium organization;GO:0046373 L-arabinose metabolic process;GO:0055127 vibrational conductance of sound to the inner ear", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LY16-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LYD5-1", "uniprot_id": "F1LYD5_RAT", "mass": 93488.0, "length": 797, "protein_name": "Zinc finger protein 40", "gene_name": "Zfp40", "organism": "Rat", "refseq_name": "zinc finger protein 40", "refseq_ac": "NP_001382067", "gene_names_uniprotkb": "Zfp40", "gene_names_refseq": "Zfp40", "protein_names_uniprotkb": "Zinc finger protein 40", "protein_names_refseq": "zinc finger protein 40", "tax_id": 10116, "disease": "", "pathway": " (rno:690661)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, 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"protein_names_refseq": "mitochondrial translation optimization 1 homolog; protein MTO1 homolog, mitochondrial", "tax_id": 10116, "disease": "nonsyndromic deafness (Disease Ontology:DOID:0050563); combined oxidative phosphorylation deficiency (Disease Ontology:DOID:0060286); combined oxidative phosphorylation deficiency 10 (Disease Ontology:DOID:0111480)", "pathway": " (rno:300852)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32157506", "class_list": "", "function": "CircMTO1 Attenuated Acute Kidney Injury Through Regulating miR-337., [RefSeq, PubMed]; Component of the GTPBP3-MTO1 complex that catalyzes the 5-taurinomethyluridine (taum(5)U) modification at the 34th wobble position (U34) of mitochondrial tRNAs (mt-tRNAs), which plays a role in mt-tRNA decoding and mitochondrial translation. Taum(5)U formation on mammalian mt-tRNA requires the presence of both GTPBP3-mediated GTPase activity and MTO1 catalytic activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding;GO:0160236 tRNA 5-taurinomethyluridine synthase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol;GO:7770010 GTPBP3-MTO1 complex", "go_biological_process": "GO:0002098 tRNA wobble uridine modification;GO:0030488 tRNA methylation;GO:0070899 mitochondrial tRNA wobble uridine modification", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1LYH3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LYQ4-1", "uniprot_id": "F1LYQ4_RAT", "mass": 54808.0, "length": 495, "protein_name": "Alpha-1-B glycoprotein like 1", "gene_name": "A1bgl1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "A1bgl1", "gene_names_refseq": "", "protein_names_uniprotkb": "Alpha-1-B glycoprotein like 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0060396 growth hormone receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LYQ4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LYZ8-1", "uniprot_id": "F1LYZ8_RAT", "mass": 88361.0, "length": 780, "protein_name": "Protein phosphatase 1 regulatory subunit 21", "gene_name": "Ppp1r21", "organism": "Rat", "refseq_name": "protein phosphatase 1 regulatory subunit 21", "refseq_ac": "NP_001258234", "gene_names_uniprotkb": "Ppp1r21; RGD1565310", "gene_names_refseq": "Ppp1r21; RGD1565310", "protein_names_uniprotkb": "Protein phosphatase 1 regulatory subunit 21; Coiled-coil domain-containing protein 128; Ferry endosomal RAB5 effector complex subunit 2; KLRAQ motif-containing protein 1", "protein_names_refseq": "protein phosphatase 1 regulatory subunit 21", "tax_id": 10116, "disease": "", "pathway": " (rno:362697)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0003729 mRNA binding;GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0005769 early endosome;GO:0016020 membrane;GO:0031901 early endosome membrane", "go_biological_process": "GO:1904580 regulation of intracellular mRNA localization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1LYZ8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LZ08-1", "uniprot_id": "F1LZ08_RAT", "mass": 43063.0, "length": 390, "protein_name": "LIM homeobox 4", "gene_name": "Lhx4", "organism": "Rat", "refseq_name": "LIM/homeobox protein Lhx4", "refseq_ac": "NP_001101818", "gene_names_uniprotkb": "Lhx4", "gene_names_refseq": "Lhx4", "protein_names_uniprotkb": "LIM homeobox 4", "protein_names_refseq": "LIM homeobox protein 4; LIM/homeobox protein Lhx4", "tax_id": 10116, "disease": "combined pituitary hormone deficiency 4 (Disease Ontology:DOID:0061017)", "pathway": " (rno:360858)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "31609018", "class_list": "", "function": "The current study was undertaken to clarify the mechanisms driving rhythmic LIM homeobox 4 (Lhx4) expression in the pineal gland and the possible regulatory impact of Lhx4 on gene transcripts involved in melatonin synthesis and other biological processes., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0008327 methyl-CpG binding;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0043066 negative regulation of apoptotic process;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1LZ08-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LZ91-1", "uniprot_id": "F1LZ91_RAT", "mass": 155463.0, "length": 1403, "protein_name": "Family with sequence similarity 135, member B", "gene_name": "Fam135b", "organism": "Rat", "refseq_name": "protein FAM135B", "refseq_ac": "NP_001414560", "gene_names_uniprotkb": "Fam135b", "gene_names_refseq": "Fam135b; RGD1308133", "protein_names_uniprotkb": "Family with sequence similarity 135, member B", "protein_names_refseq": "protein FAM135B", "tax_id": 10116, "disease": "", "pathway": " (rno:315069)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "22673903;29393594", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1LZ91-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LZG2-1", "uniprot_id": "F1LZG2_RAT", "mass": 70373.0, "length": 593, "protein_name": "Zinc finger protein 534 like 2", "gene_name": "Zfp534l2", "organism": "Rat", "refseq_name": "similar to BC021442 protein", "refseq_ac": "NP_001389457", "gene_names_uniprotkb": "Zfp534l2; RGD1561413; Rex2l3", "gene_names_refseq": "RGD1561413; Zfp534l2", "protein_names_uniprotkb": "Zinc finger protein 534 like 2", "protein_names_refseq": "similar to BC021442 protein; zinc finger protein 2 homolog; zinc finger protein 260-like", "tax_id": 10116, "disease": "", "pathway": " (rno:500585)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LZG2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LZH3-1", "uniprot_id": "F1LZH3_RAT", "mass": 85733.0, "length": 750, "protein_name": "[histone H3]-lysine(27) N-trimethyltransferase", "gene_name": "Ezh1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Ezh1", "gene_names_refseq": "", "protein_names_uniprotkb": "[histone H3]-lysine(27) N-trimethyltransferase; 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The elongator complex catalyzes the formation of carboxymethyluridine in the wobble base at position 34 in tRNAs., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0008023 transcription elongation factor complex;GO:0033588 elongator holoenzyme complex;GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0002098 tRNA wobble uridine modification", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M086-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1M090-1", "uniprot_id": "F1M090_RAT", "mass": 243761.0, "length": 2262, "protein_name": "ASXL transcriptional regulator 3", "gene_name": "Asxl3", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Asxl3", "gene_names_refseq": "", "protein_names_uniprotkb": "ASXL transcriptional regulator 3", "protein_names_refseq": "", "tax_id": 10116, "disease": "Bainbridge-Ropers syndrome (Disease Ontology:DOID:0080893)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "16641100", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0042975 peroxisome proliferator activated receptor binding", "go_cellular_component": "GO:0035517 PR-DUB complex;GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0009887 animal organ morphogenesis;GO:0051055 negative regulation of lipid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1M090-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1M0F5-1", "uniprot_id": "F1M0F5_RAT", "mass": 20890.0, "length": 184, "protein_name": "SSX family member 1", "gene_name": "Ssx1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Ssx1", "gene_names_refseq": "", "protein_names_uniprotkb": "SSX family member 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "X-linked spermatogenic failure 5 (Disease Ontology:DOID:0070596); synovial sarcoma (Disease Ontology:DOID:5485)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003714 transcription corepressor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0036126 sperm flagellum", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0007283 spermatogenesis;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1M0F5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1M111-1", "uniprot_id": "F1M111_RAT", "mass": 202306.0, "length": 1742, "protein_name": "Unconventional myosin-Va", "gene_name": "Myo5c", "organism": "Rat", "refseq_name": "unconventional myosin-Vc", "refseq_ac": "NP_001101637", "gene_names_uniprotkb": "Myo5c", "gene_names_refseq": "Myo5c", "protein_names_uniprotkb": "Unconventional myosin-Va; 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The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis. Required for proper localization of bile salt export pump ABCB11 at the apical/canalicular plasma membrane of hepatocytes., [UniProtKB, UniProtKB]; Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Can hydrolyze ATP in the presence of actin, which is essential for its function as a motor protein. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.6.2.3;3.6.4.13;3.6.4.12;2.7.11.1;3.6.1.5;3.6.4.10;3.6.4.-;2.3.2.27;5.6.2.4;3.6.5.-;5.6.2.-;3.1.-.-;2.7.7.7;2.7.7.49;3.1.13.1;4.2.99.18;7.6.2.2;7.6.2.3;7.6.2.-;5.6.1.6;7.2.2.-;3.6.1.15;3.6.4.6;3.1.3.1;3.9.1.1;6.1.1.12;3.6.1.-;2.7.4.3;3.1.4.-;3.4.24.-;3.6.-.-;3.4.21.53;5.6.2.5", "go_molecular_function": "GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0015629 actin cytoskeleton;GO:0016020 membrane", "go_biological_process": "GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0015031 protein transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M111-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1M119-1", "uniprot_id": "F1M119_RAT", "mass": 23871.0, "length": 216, "protein_name": "Coiled-coil domain containing 71-like", "gene_name": "Ccdc71l", "organism": "Rat", "refseq_name": "coiled-coil domain-containing protein 71L", "refseq_ac": "NP_001386071", "gene_names_uniprotkb": "Ccdc71l", "gene_names_refseq": "Ccdc71l; 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Cxhxorf49B; LOC102553785; LOC679774", "gene_names_refseq": "", "protein_names_uniprotkb": "Similar to human chromosome X open reading frame 49B", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M3X8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1M3Y4-1", "uniprot_id": "F1M3Y4_RAT", "mass": 14525.0, "length": 133, "protein_name": "Immunoglobulin kappa variable like 7", "gene_name": "Igkvl7", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Igkvl7", "gene_names_refseq": "", "protein_names_uniprotkb": "Immunoglobulin kappa variable like 7", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0019814 immunoglobulin complex", "go_biological_process": "GO:0006955 immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M3Y4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1M453-1", "uniprot_id": "F1M453_RAT", "mass": 83303.0, "length": 770, "protein_name": "Transcription factor SOX-30", "gene_name": "Sox30", "organism": "Rat", "refseq_name": "transcription factor SOX-30", "refseq_ac": "NP_001414119", "gene_names_uniprotkb": "Sox30", "gene_names_refseq": "Sox30", "protein_names_uniprotkb": "Transcription factor SOX-30", "protein_names_refseq": "SRY (sex determining region Y)-box 30; SRY box 30; transcription factor SOX-30", "tax_id": 10116, "disease": "lung cancer (Disease Ontology:DOID:1324); lung squamous cell carcinoma (Disease Ontology:DOID:3907); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (rno:689918)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts both as a transcriptional activator and a repressor. Binds to the DNA sequence 5'-ACAAT-3' and shows a preference for guanine residues surrounding this core motif. Binds to its own promoter and activates its own transcription. Required to activate the expression of postmeiotic genes involved in spermiogenesis. Binds to the promoter region of CTNNB1 and represses its transcription which leads to inhibition of Wnt signaling. Also inhibits Wnt signaling by binding to the CTNNB1 protein, preventing interaction of CTNNB1 with TCF7L2/TCF4., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0008013 beta-catenin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0010369 chromocenter", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007286 spermatid development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M453-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1M4A4-1", "uniprot_id": "KIF1A_RAT", "mass": 192934.0, "length": 1707, "protein_name": "Kinesin-like protein KIF1A", "gene_name": "Kif1a", "organism": "Rat", "refseq_name": "kinesin-like protein KIF1A isoform X7", "refseq_ac": "XP_017452401", "gene_names_uniprotkb": "Kif1a", "gene_names_refseq": "Kif1a", "protein_names_uniprotkb": "Kinesin-like protein KIF1A; 5.6.1.3", "protein_names_refseq": "kinesin-like protein KIF1A isoform X7", "tax_id": 10116, "disease": "hereditary sensory and autonomic neuropathy (Disease Ontology:DOID:0050548); synucleinopathy (Disease Ontology:DOID:0050890); NESCAV syndrome (Disease Ontology:DOID:0070039); hereditary sensory neuropathy type 2C (Disease Ontology:DOID:0070147); hereditary spastic paraplegia 30B (Disease Ontology:DOID:0070646); hereditary spastic paraplegia 30A (Disease Ontology:DOID:0070647); Graves ophthalmopathy (Disease Ontology:DOID:0081120); hereditary spastic paraplegia 30 (Disease Ontology:DOID:0110781); hereditary spastic paraplegia (Disease Ontology:DOID:2476); nervous system disease (Disease Ontology:DOID:863)", "pathway": " (rno:363288); (R-RNO-6811434); (R-RNO-983189)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "19338388;22673903;29166604;30021165", "class_list": "", "function": "Kinesin motor with a plus-end-directed microtubule motor activity, involved in anterograde axonal transport of synaptic vesicle precursors (By similarity). Also required for neuronal dense core vesicles (DCVs) transport to the dendritic spines and axons (PubMed:29166604, PubMed:30021165). The interaction calcium-dependent with CALM1 increases vesicle motility and interaction with the scaffolding proteins PPFIA2 and TANC2 recruits DCVs to synaptic sites (PubMed:30021165)., [UniProtKB, PubMed, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.6.1.3;3.6.5.2;3.6.5.-", "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0098992 neuronal dense core vesicle;GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0030424 axon", "go_biological_process": "GO:0098840 protein transport along microtubule;GO:0016192 vesicle-mediated transport;GO:0008089 anterograde axonal transport;GO:0048490 anterograde synaptic vesicle transport;GO:0060998 regulation of dendritic spine development", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "F1M4A4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1M4H5-1", "uniprot_id": "F1M4H5_RAT", "mass": 66810.0, "length": 656, "protein_name": "NOVA alternative splicing regulator 2", "gene_name": "Nova2", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Nova2", "gene_names_refseq": "", "protein_names_uniprotkb": "NOVA alternative splicing regulator 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:1990825 sequence-specific mRNA binding;GO:0003723 RNA binding;GO:0003729 mRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0051252 regulation of RNA metabolic process;GO:1902667 regulation of axon guidance;GO:0030182 neuron differentiation;GO:0000398 mRNA splicing, via spliceosome;GO:0021954 central nervous system neuron development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M4H5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1M4T7-1", "uniprot_id": "F1M4T7_RAT", "mass": 79211.0, "length": 706, "protein_name": "Protein-glutamine gamma-glutamyltransferase E", "gene_name": "Tgm6", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Tgm6", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein-glutamine gamma-glutamyltransferase E; 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Spryd3", "protein_names_uniprotkb": "SPRY domain containing 3", "protein_names_refseq": "SPRY domain-containing protein 3", "tax_id": 10116, "disease": "", "pathway": " (rno:315327)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M7P8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1M7Z6-1", "uniprot_id": "F1M7Z6_RAT", "mass": 14680.0, "length": 127, "protein_name": "Immunoglobulin V-set domain-containing protein", "gene_name": "AC142181.1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "AC142181.1", "gene_names_refseq": "", "protein_names_uniprotkb": "Immunoglobulin V-set domain-containing protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M7Z6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1M857-1", "uniprot_id": "F1M857_RAT", "mass": 35115.0, "length": 317, "protein_name": "Olfactory receptor family 51 subfamily AB member 3", "gene_name": "Or51ab3", "organism": "Rat", "refseq_name": "olfactory receptor Olr107", "refseq_ac": "NP_001000148", "gene_names_uniprotkb": "Or51ab3", "gene_names_refseq": "Olr107; Or51ab3", "protein_names_uniprotkb": "Olfactory receptor family 51 subfamily AB member 3", "protein_names_refseq": "olfactory receptor 107; olfactory receptor Olr107; olfactory receptor gene Olr107", "tax_id": 10116, "disease": "", "pathway": " (rno:293246)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0071396 cellular response to lipid", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1M857-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1M8A7-1", "uniprot_id": "F1M8A7_RAT", "mass": 69623.0, "length": 613, "protein_name": "L3MBTL histone methyl-lysine binding protein 4", "gene_name": "L3mbtl4", "organism": "Rat", "refseq_name": "L3MBTL histone methyl-lysine binding protein 4", "refseq_ac": "NP_001420345", "gene_names_uniprotkb": "L3mbtl4", "gene_names_refseq": "AABR07068728.1; L3mbtl4", "protein_names_uniprotkb": "L3MBTL histone methyl-lysine binding protein 4", "protein_names_refseq": "L3MBTL histone methyl-lysine binding protein 4; L3MBTL4, histone methyl-lysine binding protein; l(3)mbt-like 4; lethal(3)malignant brain tumor-like protein 4", "tax_id": 10116, "disease": "brain cancer (Disease Ontology:DOID:1319)", "pathway": " (rno:103690158)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M8A7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1M8U7-1", "uniprot_id": "F1M8U7_RAT", "mass": 57724.0, "length": 533, "protein_name": "Alkaline phosphatase", "gene_name": "Alpg", "organism": "Rat", "refseq_name": "alkaline phosphatase, germ cell type-like isoform X1", "refseq_ac": "XP_038940610", "gene_names_uniprotkb": "Alpg; Alppl2", "gene_names_refseq": "Alpg", "protein_names_uniprotkb": "Alkaline phosphatase; 3.1.3.1", "protein_names_refseq": "alkaline phosphatase, germ cell type-like isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:367308); (R-RNO-163125); (R-RNO-6811438)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.2.31;3.1.3.2;3.1.3.1;3.1.3.48;3.9.1.1;3.1.3.5;3.6.5.2;3.5.1.92;3.2.2.6;3.1.4.50;3.4.11.9", "go_molecular_function": "GO:0004035 alkaline phosphatase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0098552 side of membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M8U7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1M8W4-1", "uniprot_id": "SOX5_RAT", "mass": 83971.0, "length": 763, "protein_name": "Transcription factor SOX-5", "gene_name": "Sox5", "organism": "Rat", "refseq_name": "transcription factor SOX-5 isoform 2", "refseq_ac": "NP_001258196", "gene_names_uniprotkb": "Sox5; Sox-5", "gene_names_refseq": "Sox5l1; Sox5", "protein_names_uniprotkb": "Transcription factor SOX-5", "protein_names_refseq": "SRY (sex determining region Y)-box 5; SRY box 5; SRY-box containing gene 5-like 1; SRY-box containing gene 5; transcription factor SOX-5 isoform 2; transcription factor SOX-5", "tax_id": 10116, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); heart disease (Disease Ontology:DOID:114)", "pathway": " (rno:140587)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "24854956;26150426;26345464", "class_list": "", "function": "A spatially loaded combination of RUNX2 and SOX trio DNA loading significantly improved healing relative to empty hydrogels or either factor alone., [RefSeq, PubMed]; Study revealed that Sox5 and Sox6 prevent oligodendroglial differentiation, thus ensuring that the progenitor cells first reach their proper destination and only then lose their migratory capacity, [RefSeq, PubMed]; Transcription factor involved in chondrocytes differentiation and cartilage formation (By similarity). Specifically binds the 5'-AACAAT-3' DNA motif present in enhancers and super-enhancers and promotes expression of genes important for chondrogenesis, including cartilage matrix protein-coding genes, such as COL2A1 and AGC1 (By similarity). Required for overt chondrogenesis when condensed prechondrocytes differentiate into early stage chondrocytes: SOX5 and SOX6 cooperatively bind with SOX9 on active enhancers and super-enhancers associated with cartilage-specific genes, and thereby potentiate SOX9's ability to transactivate (PubMed:26150426). Not involved in precartilaginous condensation, the first step in chondrogenesis, during which skeletal progenitors differentiate into prechondrocytes (By similarity). Together with SOX6, required to form and maintain a pool of highly proliferating chondroblasts between epiphyses and metaphyses, to form columnar chondroblasts, delay chondrocyte prehypertrophy but promote hypertrophy, and to delay terminal differentiation of chondrocytes on contact with ossification fronts (By similarity). Binds to the proximal promoter region of the myelin protein MPZ gene (By similarity)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "F1LQN4;Q5U1X4", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0000976 transcription cis-regulatory region binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987 cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0001701 in utero embryonic development;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "F1M8W4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1M8X9-1", "uniprot_id": "F1M8X9_RAT", "mass": 206652.0, "length": 1862, "protein_name": "Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1", "gene_name": "Gbf1", "organism": "Rat", "refseq_name": "Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 isoform 3", "refseq_ac": "NP_001424991", "gene_names_uniprotkb": "Gbf1", "gene_names_refseq": "Gbf1; RGD1307160", "protein_names_uniprotkb": "Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1", "protein_names_refseq": "Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 isoform 3; Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1; golgi-specific brefeldin A resistant guanine nucleotide exchange factor 1; golgi-specific brefeldin A-resistance factor 1", "tax_id": 10116, "disease": "Charcot-Marie-Tooth disease dominant intermediate A (Disease Ontology:DOID:0110202)", "pathway": " (R-RNO-199992); (R-RNO-5620916); (R-RNO-6807878); (R-RNO-6811434)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0080025 phosphatidylinositol-3,5-bisphosphate binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005777 peroxisome;GO:0005788 endoplasmic reticulum lumen;GO:0005794 Golgi apparatus;GO:0005829 cytosol", "go_biological_process": "GO:0002263 cell activation involved in immune response;GO:0048205 COPI coating of Golgi vesicle;GO:0061162 establishment of monopolar cell polarity;GO:1903409 reactive oxygen species biosynthetic process;GO:1903420 protein localization to endoplasmic reticulum tubular network", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1M8X9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1M918-1", "uniprot_id": "F1M918_RAT", "mass": 113631.0, "length": 990, "protein_name": "NLR family, pyrin domain containing 14", "gene_name": "Nlrp14", "organism": "Rat", "refseq_name": "NLR family, pyrin domain containing 14", "refseq_ac": "NP_001419359", "gene_names_uniprotkb": "Nlrp14", "gene_names_refseq": "Nlrp14", "protein_names_uniprotkb": "NLR family, pyrin domain containing 14", "protein_names_refseq": "NACHT, LRR and PYD domains-containing protein 14; NLR family, pyrin domain containing 14", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, 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"secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0061702 canonical inflammasome complex", "go_biological_process": "GO:0006954 inflammatory response;GO:0007283 spermatogenesis;GO:0045087 innate immune response;GO:0050727 regulation of inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M918-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1M9D0-1", "uniprot_id": "F1M9D0_RAT", "mass": 69606.0, "length": 619, "protein_name": "mitogen-activated protein kinase kinase kinase", "gene_name": "Map3k2", "organism": "Rat", "refseq_name": "mitogen-activated protein kinase kinase kinase 2", "refseq_ac": "NP_612512", "gene_names_uniprotkb": "Map3k2", "gene_names_refseq": "Map3k2; Mekk2", "protein_names_uniprotkb": "mitogen-activated protein kinase kinase kinase; 2.7.11.25", "protein_names_refseq": "mitogen-activated protein kinase kinase kinase 2", "tax_id": 10116, "disease": "", "pathway": " (rno:171492)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "17003042;22673903;33506923", "class_list": "", "function": "Rap1 and MEKK2 are critical upstream signaling molecules mediating BDNF stimulation of ERK5 in central nervous system neurons, [RefSeq, PubMed]; Upregulation of miR-335 reduces myocardial injury following myocardial infarction via targeting MAP3K2., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.12.1;2.7.1.153;2.7.1.137;2.7.11.24;2.7.11.25;2.7.11.22;2.7.11.23;2.7.4.6;2.7.1.154;2.7.11.38;2.7.11.17;2.7.11.21;2.7.12.2;2.7.1.40;2.7.11.12;2.7.11.26;2.7.11.34;2.7.10.2;2.7.1.150;2.7.11.13;4.1.1.32;2.7.11.19;2.7.2.3;2.7.11.11;2.7.11.31;3.1.3.16;2.7.11.4;2.3.1.48;3.1.11.-;2.7.13.3;2.7.4.18;3.1.24.-;3.4.19.12;2.7.11.39;2.4.99.18;2.7.11.10", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0019901 protein kinase binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006468 protein phosphorylation;GO:0035556 intracellular signal transduction;GO:0000165 MAPK cascade;GO:0071260 cellular response to mechanical stimulus", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "F1M9D0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1M9P6-1", "uniprot_id": "F1M9P6_RAT", "mass": 148030.0, "length": 1311, "protein_name": "SH3 domain and tetratricopeptide repeats 2", "gene_name": "Sh3tc2", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Sh3tc2", "gene_names_refseq": "", "protein_names_uniprotkb": "SH3 domain and tetratricopeptide repeats 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "Charcot-Marie-Tooth disease type 4C (Disease Ontology:DOID:0110183)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0055037 recycling endosome;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0022011 myelination in peripheral nervous system;GO:0032287 peripheral nervous system myelin maintenance;GO:0033157 regulation of intracellular protein transport;GO:1901184 regulation of ERBB signaling pathway;GO:2001135 regulation of endocytic recycling", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M9P6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1M9S7-1", "uniprot_id": "F1M9S7_RAT", "mass": 57615.0, "length": 511, "protein_name": "Ankyrin repeat domain 53", "gene_name": "Ankrd53", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Ankrd53", "gene_names_refseq": "", "protein_names_uniprotkb": "Ankyrin repeat domain 53", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000922 spindle pole;GO:0005819 spindle", "go_biological_process": "GO:0007080 mitotic metaphase chromosome alignment;GO:0031116 positive regulation of microtubule polymerization;GO:0060236 regulation of mitotic spindle organization;GO:1902412 regulation of mitotic cytokinesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M9S7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1M9U4-1", "uniprot_id": "F1M9U4_RAT", "mass": 107345.0, "length": 958, "protein_name": "MutS protein homolog 4", "gene_name": "Msh4", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Msh4", "gene_names_refseq": "", "protein_names_uniprotkb": "MutS protein homolog 4", "protein_names_refseq": "", "tax_id": 10116, "disease": "spermatogenic failure 2 (Disease Ontology:DOID:0070164); primary ovarian insufficiency (Disease Ontology:DOID:5426)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in meiotic recombination. Required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0003690 double-stranded DNA binding;GO:0030983 mismatched DNA binding;GO:0140664 ATP-dependent DNA damage sensor activity", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0005634 nucleus;GO:0000793 condensed chromosome;GO:0005694 chromosome;GO:1990391 DNA repair complex", "go_biological_process": "GO:0007283 spermatogenesis;GO:0006298 mismatch repair;GO:0001541 ovarian follicle development;GO:0007129 homologous chromosome pairing at meiosis;GO:0007131 reciprocal meiotic recombination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M9U4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MA42-1", "uniprot_id": "F1MA42_RAT", "mass": 107905.0, "length": 997, "protein_name": "Seizure related 6 homolog", "gene_name": "Sez6", "organism": "Rat", "refseq_name": "seizure protein 6 homolog isoform X1", "refseq_ac": "XP_006247015", "gene_names_uniprotkb": "Sez6", "gene_names_refseq": "Sez6", "protein_names_uniprotkb": "Seizure related 6 homolog", "protein_names_refseq": "seizure protein 6 homolog isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:192247)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "38843836", "class_list": "", "function": "May play a role in cell-cell recognition and in neuronal membrane signaling. Seems to be important for the achievement of the necessary balance between dendrite elongation and branching during the elaboration of a complex dendritic arbor. Involved in the development of appropriate excitatory synaptic connectivity., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0005783 endoplasmic reticulum;GO:0043025 neuronal cell body;GO:0043197 dendritic spine;GO:0043198 dendritic shaft", "go_biological_process": "GO:0008344 adult locomotory behavior;GO:0060079 excitatory postsynaptic potential;GO:1990051 activation of protein kinase C activity;GO:0021680 cerebellar Purkinje cell layer development;GO:2000171 negative regulation of dendrite development", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "F1MA42-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MA97-1", "uniprot_id": "F1MA97_RAT", "mass": 183778.0, "length": 1645, "protein_name": "Thrombospondin type-1 domain-containing protein 7A", "gene_name": "Thsd7a", "organism": "Rat", "refseq_name": "thrombospondin type-1 domain-containing protein 7A precursor", "refseq_ac": "NP_001178899", "gene_names_uniprotkb": "Thsd7a", "gene_names_refseq": "RGD1566201; Thsd7a", "protein_names_uniprotkb": "Thrombospondin type-1 domain-containing protein 7A", "protein_names_refseq": "thrombospondin type-1 domain-containing protein 7A precursor; thrombospondin type-1 domain-containing protein 7A; thrombospondin, type I, domain containing 7A", "tax_id": 10116, "disease": "", "pathway": " (rno:500032); (R-RNO-5173214)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "34876395;38843836", "class_list": "", "function": "Correlation Between THSD7A Expression and Tumor Characteristics of Azoxymethane-Induced Colon Cancer Model in Rats., [RefSeq, PubMed]; Plays a role in actin cytoskeleton rearrangement., [UniProtKB, UniProtKB]; The soluble form promotes endothelial cell migration and filopodia formation during sprouting angiogenesis via a FAK-dependent mechanism., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0098846 podocyte foot", "go_biological_process": "GO:0001525 angiogenesis;GO:0030154 cell differentiation;GO:0030036 actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "F1MA97-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MAD2-1", "uniprot_id": "INADL_RAT", "mass": 199468.0, "length": 1836, "protein_name": "InaD-like protein", "gene_name": "Patj", "organism": "Rat", "refseq_name": "inaD-like protein", "refseq_ac": "NP_536323", "gene_names_uniprotkb": "Patj; Cipp; Inadl", "gene_names_refseq": "Inadl2; Inadl; Patj; RGD1565362", "protein_names_uniprotkb": "InaD-like protein; Channel-interacting PDZ domain-containing protein; Inadl protein; Pals1-associated tight junction protein; Protein associated to tight junctions", "protein_names_refseq": "InaD-like 2; PDZ domain protein; channel-interacting PDZ domain-containing protein; inaD-like protein; pals1-associated tight junction protein; protein associated to tight junctions", "tax_id": 10116, "disease": "sensorineural hearing loss (Disease Ontology:DOID:10003)", "pathway": " (rno:140581)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "18621709;22337881;22673903", "class_list": "", "function": "Scaffolding protein that facilitates the localization of proteins to the cell membrane (By similarity). Required for the correct formation of tight junctions and epithelial apico-basal polarity (By similarity). Acts (via its L27 domain) as an apical connector and elongation factor for multistranded TJP1/ZO1 condensates that form a tight junction belt, thereby required for the formation of the tight junction-mediated cell barrier (By similarity). Positively regulates epithelial cell microtubule elongation and cell migration, possibly via facilitating localization of PRKCI/aPKC and PAR3D/PAR3 at the leading edge of migrating cells (By similarity). Plays a role in the correct reorientation of the microtubule-organizing center during epithelial migration (By similarity). May regulate the surface expression and/or function of ASIC3 in sensory neurons (By similarity). May recruit ARHGEF18 to apical cell-cell boundaries (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Scaffolding protein that facilitates the localization of proteins to the cell membrane. Required for the correct formation of tight junctions and epithelial apico-basal polarity. Acts (via its L27 domain) as an apical connector and elongation factor for multistranded TJP1/ZO1 condensates that form a tight junction belt, thereby required for the formation of the tight junction-mediated cell barrier. Positively regulates epithelial cell microtubule elongation and cell migration, possibly via facilitating localization of PRKCI/aPKC and PAR3D/PAR3 at the leading edge of migrating cells. Plays a role in the correct reorientation of the microtubule-organizing center during epithelial migration. May regulate the surface expression and/or function of ASIC3 in sensory neurons. May recruit ARHGEF18 to apical cell-cell boundaries., [UniProtKB, UniProtKB, UniProtKB]; The crystal structure of a 4-L27 domain-containing heterotrimer derived from the tripartite complex Patj/Pals1/Mals2, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005923 bicellular tight junction;GO:0030054 cell junction;GO:0031252 cell leading edge", "go_biological_process": "GO:0120192 tight junction assembly;GO:0035089 establishment of apical/basal cell polarity;GO:0032880 regulation of protein localization;GO:0010634 positive regulation of epithelial cell migration;GO:0070507 regulation of microtubule cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "F1MAD2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MAF8-1", "uniprot_id": "F1MAF8_RAT", "mass": 231555.0, "length": 2076, "protein_name": "Autophagy related 2B", "gene_name": "Atg2b", "organism": "Rat", "refseq_name": "autophagy-related protein 2 homolog B", "refseq_ac": "NP_001414704", "gene_names_uniprotkb": "Atg2b", "gene_names_refseq": "Atg2b; RGD1304878", "protein_names_uniprotkb": "Autophagy related 2B", "protein_names_refseq": "autophagy-related protein 2 homolog B", "tax_id": 10116, "disease": "", "pathway": " (rno:314415)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.-.-;1.6.5.5", "go_molecular_function": "GO:0043495 protein-membrane adaptor activity;GO:0032266 phosphatidylinositol-3-phosphate binding;GO:0120013 lipid transfer activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0034045 phagophore assembly site membrane;GO:0000407 phagophore assembly site;GO:0061908 phagophore", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0000422 autophagy of mitochondrion;GO:0034727 piecemeal microautophagy of the nucleus;GO:0061709 reticulophagy;GO:0061723 glycophagy", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1MAF8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MAG0-1", "uniprot_id": "F1MAG0_RAT", "mass": 56900.0, "length": 513, "protein_name": "Gasdermin E", "gene_name": "Gsdme", "organism": "Rat", "refseq_name": "gasdermin-E isoform 1", "refseq_ac": "XP_038963654", "gene_names_uniprotkb": "Gsdme", "gene_names_refseq": "Dfna5h; Dfna5; Gsdme", "protein_names_uniprotkb": "Gasdermin E", "protein_names_refseq": "DFNA5, deafness associated tumor suppressor; deafness, autosomal dominant 5 homolog; gasdermin-E isoform 1; non-syndromic hearing impairment protein 5", "tax_id": 10116, "disease": "autosomal dominant nonsyndromic deafness 5 (Disease Ontology:DOID:0110575); sensorineural hearing loss (Disease Ontology:DOID:10003); lung adenocarcinoma (Disease Ontology:DOID:3910)", "pathway": " (rno:353316); (R-RNO-111457); (R-RNO-111458); (R-RNO-111461); (R-RNO-5620971); (R-RNO-5686938)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "40200275", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0022829 wide pore channel activity;GO:1901612 cardiolipin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0008285 negative regulation of cell population proliferation;GO:0043410 positive regulation of MAPK cascade;GO:2001244 positive regulation of intrinsic apoptotic signaling pathway;GO:0071356 cellular response to tumor necrosis factor;GO:0070269 pyroptotic inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "F1MAG0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MAG7-1", "uniprot_id": "F1MAG7_RAT", "mass": 163186.0, "length": 1452, "protein_name": "Receptor-type tyrosine-protein phosphatase U", "gene_name": "Ptpru", "organism": "Rat", "refseq_name": "receptor-type tyrosine-protein phosphatase U isoform X1", "refseq_ac": "XP_017448609", "gene_names_uniprotkb": "Ptpru", "gene_names_refseq": "Ptpru", "protein_names_uniprotkb": "Receptor-type tyrosine-protein phosphatase U; 3.1.3.48; Pancreatic carcinoma phosphatase 2; Receptor-type protein-tyrosine phosphatase psi", "protein_names_refseq": "receptor-type tyrosine-protein phosphatase U isoform X1", "tax_id": 10116, "disease": "membranous glomerulonephritis (Disease Ontology:DOID:10976); nephrosis (Disease Ontology:DOID:2527)", "pathway": " (R-RNO-1433557)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Tyrosine-protein phosphatase which dephosphorylates CTNNB1. Regulates CTNNB1 function both in cell adhesion and signaling. May function in cell proliferation and migration and play a role in the maintenance of epithelial integrity. May play a role in megakaryocytopoiesis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.3.48;2.7.10.1;3.1.3.16;3.1.3.2;3.1.3.21;3.1.3.18;3.1.3.67;3.1.3.-;3.1.3.27;3.1.3.5", "go_molecular_function": "GO:0042802 identical protein binding;GO:0008013 beta-catenin binding;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005911 cell-cell junction;GO:0016020 membrane", "go_biological_process": "GO:0034109 homotypic cell-cell adhesion;GO:0008285 negative regulation of cell population proliferation;GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0030336 negative regulation of cell migration;GO:0051384 response to glucocorticoid", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MAG7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MAM1-1", "uniprot_id": "F1MAM1_RAT", "mass": 50677.0, "length": 458, "protein_name": "F-box/WD repeat-containing protein 9", "gene_name": "Fbxw9", "organism": "Rat", "refseq_name": "F-box/WD repeat-containing protein 9", "refseq_ac": "NP_001075103", "gene_names_uniprotkb": "Fbxw9", "gene_names_refseq": "Fbxw9", "protein_names_uniprotkb": "F-box/WD repeat-containing protein 9; F-box and WD-40 domain-containing protein 9", "protein_names_refseq": "F-box and WD-40 domain protein 9; F-box/WD repeat-containing protein 9", "tax_id": 10116, "disease": "", "pathway": " (rno:288921); (R-RNO-8951664); (R-RNO-983168)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MAM1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MAP1-1", "uniprot_id": "F1MAP1_RAT", "mass": 30683.0, "length": 268, "protein_name": "Zinc finger protein OZF", "gene_name": "LOC120095168", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LOC120095168", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger protein OZF; Only zinc finger protein; Zinc finger protein 146", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:120095168)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MAP1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MAS0-1", "uniprot_id": "F1MAS0_RAT", "mass": 51531.0, "length": 455, "protein_name": "Keratin 32", "gene_name": "Krt32", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Krt32", "gene_names_refseq": "", "protein_names_uniprotkb": "Keratin 32", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:450230); (R-RNO-6805567); (R-RNO-6809371)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005198 structural molecule activity;GO:0030280 structural constituent of skin epidermis", "go_cellular_component": "GO:0005882 intermediate filament;GO:0005856 cytoskeleton;GO:0045095 keratin filament", "go_biological_process": "GO:0030855 epithelial cell differentiation;GO:0045109 intermediate filament organization;GO:0002009 morphogenesis of an epithelium", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MAS0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F6PUS4-1", "uniprot_id": "F6PUS4_RAT", "mass": 79375.0, "length": 730, "protein_name": "SH3 domain containing 21", "gene_name": "Sh3d21", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Sh3d21", "gene_names_refseq": "", "protein_names_uniprotkb": "SH3 domain containing 21", "protein_names_refseq": "", "tax_id": 10116, "disease": "nephrotic syndrome (Disease Ontology:DOID:1184); 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LOC679082", "gene_names_refseq": "Arhgap19", "protein_names_uniprotkb": "Rho GTPase-activating protein 19; Rho-type GTPase-activating protein 19", "protein_names_refseq": "rho GTPase-activating protein 19", "tax_id": 10116, "disease": "", "pathway": " (rno:679082); (R-RNO-8980692)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0051056 regulation of small GTPase mediated signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R5V4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "M0R5W9-1", "uniprot_id": "M0R5W9_RAT", "mass": 51785.0, "length": 460, "protein_name": "Zinc finger protein 764 like 1", "gene_name": "Zfp764l1", "organism": "Rat", "refseq_name": "zinc finger protein 764 like 1", "refseq_ac": "NP_001403323", "gene_names_uniprotkb": "Zfp764l1", "gene_names_refseq": "Zfp764l1; 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LOC688292", "gene_names_refseq": "Card14", "protein_names_uniprotkb": "Caspase recruitment domain-containing protein 14", "protein_names_refseq": "caspase recruitment domain-containing protein 14 isoform X4", "tax_id": 10116, "disease": "psoriasis 2 (Disease Ontology:DOID:0080475); pityriasis rubra pilaris (Disease Ontology:DOID:9212)", "pathway": " (rno:688292)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a scaffolding protein that can activate the inflammatory transcription factor NF-kappa-B and p38/JNK MAP kinase signaling pathways. Forms a signaling complex with BCL10 and MALT1, and activates MALT1 proteolytic activity and inflammatory gene expression. MALT1 is indispensable for CARD14-induced activation of NF-kappa-B and p38/JNK MAP kinases. May play a role in signaling mediated by TRAF2, TRAF3 and TRAF6 and protects cells against apoptosis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0050700 CARD domain binding;GO:0035591 signaling adaptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0032449 CBM complex", "go_biological_process": "GO:0001934 positive regulation of protein phosphorylation;GO:0043066 negative regulation of apoptotic process;GO:0033209 tumor necrosis factor-mediated signaling pathway;GO:0007165 signal transduction;GO:0050776 regulation of immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R6R8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "M0R6Y4-1", "uniprot_id": "M0R6Y4_RAT", "mass": 22201.0, "length": 194, "protein_name": "Similar to human chromosome 20 open reading frame 173", "gene_name": "C3h20orf173", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "C3h20orf173; LOC102550306", "gene_names_refseq": "", "protein_names_uniprotkb": "Similar to human chromosome 20 open reading frame 173", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0097503 sialylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R6Y4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "M0R769-1", "uniprot_id": "M0R769_RAT", "mass": 35343.0, "length": 314, "protein_name": "Olfactory receptor", "gene_name": "Or5g29", "organism": "Rat", "refseq_name": "olfactory receptor Olr446", "refseq_ac": "NP_001001050", "gene_names_uniprotkb": "Or5g29", "gene_names_refseq": "Olr446; Or5g29", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 446; olfactory receptor Olr446; olfactory receptor gene Olr446", "tax_id": 10116, "disease": "", "pathway": " (rno:405937)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R769-1", "record_type": "protein" }, { "uniprot_canonical_ac": "M0R7D0-1", "uniprot_id": "M0R7D0_RAT", "mass": 48805.0, "length": 437, "protein_name": "cyclin-dependent kinase", "gene_name": "Cdk15", "organism": "Rat", "refseq_name": "cyclin-dependent kinase 15", "refseq_ac": "NP_001418168", "gene_names_uniprotkb": "Cdk15", "gene_names_refseq": "Cdk15; 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LOC687071", "gene_names_refseq": "", "protein_names_uniprotkb": "Ethanolamine-phosphate phospho-lyase; 4.2.3.2; Alanine--glyoxylate aminotransferase 2-like 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-1483213)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the pyridoxal-phosphate-dependent breakdown of phosphoethanolamine, converting it to ammonia, inorganic phosphate and acetaldehyde., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "4.2.3.2", "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0050459 ethanolamine-phosphate phospho-lyase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0016020 membrane", "go_biological_process": "GO:0055088 lipid homeostasis;GO:0032094 response to food;GO:0006649 phospholipid transfer to membrane;GO:0071385 cellular response to glucocorticoid stimulus;GO:1905372 ceramide phosphoethanolamine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R7F6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "M0R7G1-1", "uniprot_id": "M0R7G1_RAT", "mass": 27930.0, "length": 254, "protein_name": "Kallikrein-related peptidase 15", "gene_name": "Klk15", "organism": "Rat", "refseq_name": "kallikrein-related peptidase 15 precursor", "refseq_ac": "NP_001414564", "gene_names_uniprotkb": "Klk15", "gene_names_refseq": "Klk15", "protein_names_uniprotkb": "Kallikrein-related peptidase 15", "protein_names_refseq": "kallikrein-15-like; 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Stat6", "organism": "Rat", "refseq_name": "nuclear envelope integral membrane protein 1", "refseq_ac": "NP_001258178", "gene_names_uniprotkb": "Nemp1; Stat6; Stat6", "gene_names_refseq": "Nemp1; Tmem194a; Tmem194", "protein_names_uniprotkb": "Nuclear envelope integral membrane protein 1", "protein_names_refseq": "nuclear envelope integral membrane protein 1; transmembrane protein 194A", "tax_id": 10116, "disease": "renal fibrosis (Disease Ontology:DOID:0050855); prostate cancer (Disease Ontology:DOID:10283); prostate carcinoma (Disease Ontology:DOID:10286); lipoid nephrosis (Disease Ontology:DOID:10966); urinary schistosomiasis (Disease Ontology:DOID:1394); rectum adenocarcinoma (Disease Ontology:DOID:1996); colon adenocarcinoma (Disease Ontology:DOID:234); asthma (Disease Ontology:DOID:2841); gastric adenocarcinoma (Disease Ontology:DOID:3717); myocarditis (Disease Ontology:DOID:820); autosomal dominant polycystic kidney disease (Disease Ontology:DOID:898)", "pathway": " (rno:679504); (R-RNO-186763); (R-RNO-3249367); (R-RNO-6785807)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Carries out a dual function: signal transduction and activation of transcription. 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(R-RNO-69473)", "pathway_count": 11, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 1, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.6.2.3;3.6.4.13;3.6.4.12;2.7.7.7;3.1.-.-;2.7.11.1;3.6.1.5;3.6.4.10;3.6.4.-;2.3.2.27;5.6.2.4;3.6.5.-;5.6.2.-;2.7.7.49;5.6.2.1;3.1.13.1;4.2.99.18;7.6.2.2;7.6.2.3;7.6.2.-;5.6.1.6;7.2.2.-;3.6.1.15;3.6.4.6;3.1.11.-;3.1.3.1;3.9.1.1;6.1.1.12;3.6.1.-;3.1.22.-;2.7.4.3;3.1.4.-;3.4.24.-;3.6.-.-;2.7.11.17;2.4.99.18;3.4.21.53;2.3.1.48;2.3.1.-;5.6.2.5;6.5.1.1", "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0032039 integrator complex;GO:0160232 INTAC complex;GO:0005654 nucleoplasm", "go_biological_process": "GO:0034243 regulation of transcription elongation by RNA polymerase II;GO:0016180 snRNA processing;GO:0034472 snRNA 3'-end processing;GO:0160240 RNA polymerase II transcription initiation surveillance;GO:1904385 cellular response to angiotensin", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A096MJ28-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A096MJG2-1", "uniprot_id": "A0A096MJG2_RAT", "mass": 34497.0, "length": 310, "protein_name": "Olfactory receptor", "gene_name": "LOC120094365", "organism": "Rat", "refseq_name": "olfactory receptor Olr1197", "refseq_ac": "NP_001001120", "gene_names_uniprotkb": "LOC120094365; LOC120094366; Or8b12d", "gene_names_refseq": "Olr1197; Or8b12d", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1197; olfactory receptor Olr1197; olfactory receptor gene Olr1197", "tax_id": 10116, "disease": "", "pathway": " (rno:406021)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3ZI53", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A096MJG2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A096MJH9-1", "uniprot_id": "A0A096MJH9_RAT", "mass": 33571.0, "length": 291, "protein_name": "Popeye domain containing 3", "gene_name": "Popdc3", "organism": "Rat", "refseq_name": "popeye domain-containing protein 3 isoform 1", "refseq_ac": "NP_001402600", "gene_names_uniprotkb": "Popdc3", "gene_names_refseq": "Popdc3", "protein_names_uniprotkb": "Popeye domain containing 3", "protein_names_refseq": "popeye domain containing 3; popeye domain-containing protein 3 isoform 1; popeye domain-containing protein 3", "tax_id": 10116, "disease": "autosomal recessive limb-girdle muscular dystrophy type 26 (Disease Ontology:DOID:0061131); muscular dystrophy (Disease Ontology:DOID:9884)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030552 cAMP binding", "go_cellular_component": "GO:0016020 membrane;GO:0042383 sarcolemma", "go_biological_process": "GO:0007507 heart development;GO:0042391 regulation of membrane potential;GO:0051146 striated muscle cell differentiation;GO:0007519 skeletal muscle tissue development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A096MJH9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A096MJY1-1", "uniprot_id": "A0A096MJY1_RAT", "mass": 62958.0, "length": 555, "protein_name": "Glypican 6", "gene_name": "Gpc6", "organism": "Rat", "refseq_name": "glypican-6 precursor", "refseq_ac": "NP_001414362", "gene_names_uniprotkb": "Gpc6; ENSRNOG00000062503", "gene_names_refseq": "Gpc6", "protein_names_uniprotkb": "Glypican 6", "protein_names_refseq": "glypican-6 precursor", "tax_id": 10116, "disease": "omodysplasia 1 (Disease Ontology:DOID:0080844)", "pathway": " (rno:691984); (R-RNO-1971475); (R-RNO-2022928); (R-RNO-2024096); (R-RNO-975634); (R-RNO-9769739)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cell surface proteoglycan., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0031012 extracellular matrix;GO:0045202 synapse", "go_biological_process": "GO:0016477 cell migration;GO:0009966 regulation of signal transduction;GO:0098696 regulation of neurotransmitter receptor localization to postsynaptic specialization membrane", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A096MJY1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZFJ3-1", "uniprot_id": "3BP1_RAT", "mass": 74852.0, "length": 689, "protein_name": "SH3 domain-binding protein 1", "gene_name": "Sh3bp1", "organism": "Rat", "refseq_name": "SH3 domain-binding protein 1", "refseq_ac": "NP_001165452", "gene_names_uniprotkb": "Sh3bp1", "gene_names_refseq": "Sh3bp1", "protein_names_uniprotkb": "SH3 domain-binding protein 1", "protein_names_refseq": "SH3 domain-binding protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:300067); (R-RNO-9013149)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "21658605;22673903;29393594", "class_list": "", "function": "GTPase activating protein/GAP which specifically converts GTP-bound Rho-type GTPases including RAC1 and CDC42 in their inactive GDP-bound form. By specifically inactivating RAC1 at the leading edge of migrating cells, it regulates the spatiotemporal organization of cell protrusions which is important for proper cell migration (PubMed:21658605). Also negatively regulates CDC42 in the process of actin remodeling and the formation of epithelial cell junctions. Through its GAP activity toward RAC1 and/or CDC42 plays a specific role in phagocytosis of large particles. Specifically recruited by a PI3 kinase/PI3K-dependent mechanism to sites of large particles engagement, inactivates RAC1 and/or CDC42 allowing the reorganization of the underlying actin cytoskeleton required for engulfment. It also plays a role in angiogenesis and the process of repulsive guidance as part of a semaphorin-plexin signaling pathway. Following the binding of PLXND1 to extracellular SEMA3E it dissociates from PLXND1 and inactivates RAC1, inducing the intracellular reorganization of the actin cytoskeleton and the collapse of cells (By similarity)., [UniProtKB, PubMed, UniProtKB]; SH3BP1 downregulates Rac1 at the motile-cell front and is required for cell motility., [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0017124 SH3 domain binding;GO:0030215 semaphorin receptor binding", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005912 adherens junction", "go_biological_process": "GO:0006911 phagocytosis, engulfment;GO:0007015 actin filament organization;GO:0016477 cell migration;GO:0030834 regulation of actin filament depolymerization;GO:0032956 regulation of actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "D3ZFJ3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P28841-1", "uniprot_id": "NEC2_RAT", "mass": 70753.0, "length": 637, "protein_name": "Neuroendocrine convertase 2", "gene_name": "Pcsk2", "organism": "Rat", "refseq_name": "neuroendocrine convertase 2 precursor", "refseq_ac": "NP_036878", "gene_names_uniprotkb": "Pcsk2; Nec-2; Nec2; Rpc2", "gene_names_refseq": "Pcsk2", "protein_names_uniprotkb": "Neuroendocrine convertase 2; 3.4.21.94; KEX2-like endoprotease 2; NEC 2; PC2; Prohormone convertase 2; Proprotein convertase 2", "protein_names_refseq": "KEX2-like endoprotease 2; NEC 2; PC2; neuroendocrine convertase 2 precursor; neuroendocrine convertase 2; prohormone convertase 2; proprotein convertase 2", "tax_id": 10116, "disease": "prostate cancer (Disease Ontology:DOID:10283); prostate carcinoma (Disease Ontology:DOID:10286); alcohol use disorder (Disease Ontology:DOID:1574); breast cancer (Disease Ontology:DOID:1612); myocardial infarction (Disease Ontology:DOID:5844); chronic kidney disease (Disease Ontology:DOID:784); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (rno:25121)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "1791845;1954888;19628676;24090084;26755731", "class_list": "", "function": "Serine endopeptidase which is involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Responsible for the release of glucagon from proglucagon in pancreatic A cells., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; The nutrient sensor sirtuin 1 regulates the production of CRH post-translationally by affecting PC2 post-translationally by affecting PC2., [RefSeq, PubMed]; The presence of PC and GOAT in the cells, as well as n-octanoic acid in the culture medium, was necessary to produce n-octanoyl ghrelin., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 1, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 2, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 5, "disease_count": 7, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane;GO:0030141 secretory granule;GO:0030425 dendrite;GO:0034774 secretory granule lumen", "go_biological_process": "GO:0006508 proteolysis;GO:0007399 nervous system development;GO:0016485 protein processing;GO:0016486 peptide hormone processing;GO:0016540 protein autoprocessing", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P28841-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P49134-1", "uniprot_id": "ITB1_RAT", "mass": 88495.0, "length": 799, "protein_name": "Integrin beta-1", "gene_name": "Itgb1", "organism": "Rat", "refseq_name": "integrin beta-1 precursor", "refseq_ac": "NP_058718", "gene_names_uniprotkb": "Itgb1", "gene_names_refseq": "Itgb1", "protein_names_uniprotkb": "Integrin beta-1; Beta OL; Beta oligodendroglia; Fibronectin receptor subunit beta; VLA-4 subunit beta", "protein_names_refseq": "beta OL; beta oligodendroglia; collagen alpha-1(I) chain-like; fibronectin receptor subunit beta; integrin VLA-4 subunit beta; integrin beta 1 (fibronectin receptor beta); integrin beta-1 precursor; integrin beta-1", "tax_id": 10116, "disease": "Sertoli cell-only syndrome (Disease Ontology:DOID:0050457); Hirschsprung's disease (Disease Ontology:DOID:10487); hydrocephalus (Disease Ontology:DOID:10908); cancer (Disease Ontology:DOID:162); glomerulonephritis (Disease Ontology:DOID:2921); IgA glomerulonephritis (Disease Ontology:DOID:2986); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung small cell carcinoma (Disease Ontology:DOID:5409); myocardial infarction (Disease Ontology:DOID:5844)", "pathway": " (rno:24511); (R-RNO-1566948); (R-RNO-1566977); (R-RNO-198933); (R-RNO-202733); (R-RNO-210991); (R-RNO-2129379); (R-RNO-216083); (R-RNO-2173789); (R-RNO-3000157); (R-RNO-3000170); (R-RNO-3000178); (R-RNO-445144); (R-RNO-446343); (R-RNO-8874081); (R-RNO-8875513); (R-RNO-9013149); (R-RNO-9013404); (R-RNO-9013408); (R-RNO-9013423); (R-RNO-9634597); (R-RNO-9860927)", "pathway_count": 22, "publication_count": 7, "publication_id_list": "33640375;33847460;35655382;36336138;38063256;38843836;7541764", "class_list": "", "function": "ITGB1 Suppresses Autophagy Through Inhibiting The mTORC2/AKT Signaling Pathway In H9C2 Cells., [RefSeq, PubMed]; Inhibited effect of an RGD peptide hydrogel on the expression of beta1-integrin, FAK, and Akt in Tenon's capsule fibroblasts., [RefSeq, PubMed]; Integrin-dependent microgliosis mediates ketamine-induced neuronal apoptosis during postnatal rat retinal development., [RefSeq, PubMed]; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-6/beta-1 (ITGA6:ITGB1) is present in oocytes and is involved in sperm-egg fusion. Integrin alpha-4/beta-1 is a receptor for VCAM1 and recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. When associated with alpha-7/beta-1 integrin, regulates cell adhesion and laminin matrix deposition. Involved in promoting endothelial cell motility and angiogenesis. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process and the formation of mineralized bone nodules. May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and RACK1, serves as a platform for SRC activation or inactivation. Plays a mechanistic adhesive role during telophase, required for the successful completion of cytokinesis (By similarity). ITGA4:ITGB1 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling. ITGA4:ITGB1 and ITGA5:ITGB1 bind to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1. ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1. ITGA5:ITGB1 is a receptor for IL1B and binding is essential for IL1B signaling (By similarity). ITGA5:ITGB3 is a receptor for soluble CD40LG and is required for CD40/CD40LG signaling (By similarity). Plays an important role in myoblast differentiation and fusion during skeletal myogenesis (By similarity). ITGA9:ITGB1 may play a crucial role in SVEP1/polydom-mediated myoblast cell adhesion (By similarity). Integrins ITGA9:ITGB1 and ITGA4:ITGB1 repress PRKCA-mediated L-type voltage-gated channel Ca(2+) influx and ROCK-mediated calcium sensitivity in vascular smooth muscle cells via their interaction with SVEP1, thereby inhibit vasocontraction (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Kcnh2 deletion is associated with rat embryonic development defects via destruction of KCNH2-integrin beta1 complex., [RefSeq, PubMed]; Synergistic regulation of microglia differentiation by CD93 and integrin beta1 in the rat pneumococcal meningitis model., [RefSeq, PubMed]", "predicted_glycosites": 10, "predicted_n_glycosites": 10, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 2, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 2, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 2, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 9, "glyco_site_count": 12, "binding_glycan_count": 0, "secondary_ac_list": "A2RRT8", "ec_number_list": "", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0002020 protease binding;GO:0003779 actin binding;GO:0005102 signaling receptor binding;GO:0005178 integrin binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0035748 myelin sheath abaxonal region;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005911 cell-cell junction", "go_biological_process": "GO:0001708 cell fate specification;GO:0071559 response to transforming growth factor beta;GO:0007161 calcium-independent cell-matrix adhesion;GO:0023035 CD40 signaling pathway;GO:0001525 angiogenesis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P49134-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1M7H8-1", "uniprot_id": "F1M7H8_RAT", "mass": 27248.0, "length": 248, "protein_name": "Granszyme B-like 1", "gene_name": "LOC103690372", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LOC103690372; Gzmbl1", "gene_names_refseq": "", "protein_names_uniprotkb": "Granszyme B-like 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M7H8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P12760-1", "uniprot_id": "NMU_RAT", "mass": 19403.0, "length": 174, "protein_name": "Neuromedin-U", "gene_name": "Nmu", "organism": "Rat", "refseq_name": "neuromedin-U precursor", "refseq_ac": "NP_071575", "gene_names_uniprotkb": "Nmu", "gene_names_refseq": "Nmu", "protein_names_uniprotkb": "Neuromedin-U; Prepro-NMU", "protein_names_refseq": "neuromedin U precursor-related peptide/neuromedin U preproprotein; neuromedin-U precursor", "tax_id": 10116, "disease": "obesity (Disease Ontology:DOID:9970)", "pathway": " (rno:63887); (R-RNO-375276); (R-RNO-416476); (R-RNO-418594)", "pathway_count": 4, "publication_count": 11, "publication_id_list": "10894543;1448109;15635449;28400225;28874765;31069918;31344393;3178840;3411332;34916591;7916966", "class_list": "", "function": "Brain region-specific neuromedin U signalling regulates alcohol-related behaviours and food intake in rodents., [RefSeq, PubMed]; Does not function as a ligand for either NMUR1 or NMUR2 (PubMed:28874765). Indirectly induces prolactin release although its potency is much lower than that of neuromedin precursor-related peptide 36 (PubMed:28874765)., [UniProtKB, PubMed]; Multifunctional neuropeptide that acts via two G protein-coupled receptors, NMUR1 and NMUR2 (PubMed:28874765). Functionally, is involved in pleiotropic roles, including regulation of feeding, energy balance, blood pressure and smooth muscle contraction (PubMed:10894543, PubMed:3178840). Additionally modulates hormone release and inflammatory responses in a tissue- and receptor-dependent manner (By similarity). Mechanistically, binding to NMUR1 or NMUR2 results in coupling of receptors to Galpha proteins, namely GNAQ/Gaq or GNA11/Ga11 and GNAI1/Gai subunits. GNAQ/Gaq or GNA11/Ga11 coupling leads to the activation of a phospholipase C (PLC), which hydrolyzes PIP2 (phosphatidylinositol 4,5-bisphosphate) into DAG (diacylglycerol) and IP3 (inositol trisphosphate), and subsequent intracellular calcium mobilization via IP3 receptors on the endoplasmic reticulum. GNAI1/Gai coupling inhibits forskolin-stimulated cAMP accumulation. In pancreatic beta cells, regulates insulin secretion through NMUR1 coupled to GNAI2 and GNAO1, resulting in reduced intracellular Ca2+ influx and cAMP levels (By similarity). Through NMUR1 in Th2-type T cells, enhances type 2 cytokine secretion and modulates inflammatory responses via activation of PLC-calcineurin-MEK and PI3K signaling pathways (By similarity)., [UniProtKB, PubMed, PubMed, UniProtKB, PubMed, UniProtKB]; PEGylated rat NMU-8 showed potent and robust anorectic activity and anti-obesity effect in diet-induced obesity mice., [RefSeq, PubMed]; Role of neuropeptide neuromedin U in the nucleus accumbens shell in cocaine self-administration in male rats., [RefSeq, PubMed]; This is the first report to demonstrate that Nmu expression in the pars tuberalis is regulated by adenosine, which acts as an intravital central metabolic signal, in addition to melatonin, which acts as an external photoperiodic environmental signal., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A250SHE5", "ec_number_list": "", "go_molecular_function": "GO:0042922 neuromedin U receptor binding;GO:0031839 type 1 neuromedin U receptor binding;GO:0031840 type 2 neuromedin U receptor binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0043195 terminal bouton", "go_biological_process": "GO:1903999 negative regulation of eating behavior;GO:0045187 regulation of circadian sleep/wake cycle, sleep;GO:2000252 negative regulation of feeding behavior;GO:0060455 negative regulation of gastric acid secretion;GO:0001659 temperature homeostasis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P12760-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P51593-1", "uniprot_id": "HUWE1_RAT", "mass": 489705.0, "length": 4454, "protein_name": "E3 ubiquitin-protein ligase HUWE1", "gene_name": "Huwe1", "organism": "Rat", "refseq_name": "E3 ubiquitin-protein ligase HUWE1 isoform X6", "refseq_ac": "XP_063136284", "gene_names_uniprotkb": "Huwe1; Ureb1", "gene_names_refseq": "Huwe1; URE-B1", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase HUWE1; 2.3.2.26; HECT, UBA and WWE domain-containing protein 1; HECT-type E3 ubiquitin transferase HUWE1; URE-B1; URE-binding protein 1; Upstream regulatory element-binding protein 1", "protein_names_refseq": "E3 ubiquitin-protein ligase HUWE1 isoform X6", "tax_id": 10116, "disease": "syndromic X-linked intellectual disability (Disease Ontology:DOID:0060309); syndromic X-linked intellectual disability Turner type (Disease Ontology:DOID:0060811); non-syndromic X-linked intellectual disability 50 (Disease Ontology:DOID:0112029)", "pathway": " (rno:501546); (R-RNO-6798695); (R-RNO-983168)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "17823942;18683930;22673903;7478539;7968380", "class_list": "", "function": "E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Regulates apoptosis by catalyzing the polyubiquitination and degradation of MCL1 (By similarity). Mediates monoubiquitination of DNA polymerase beta (POLB) at 'Lys-41', 'Lys-61' and 'Lys-81', thereby playing a role in base-excision repair (By similarity). Also ubiquitinates the p53/TP53 tumor suppressor and core histones including H1, H2A, H2B, H3 and H4 (PubMed:7478539). Ubiquitinates MFN2 to negatively regulate mitochondrial fusion in response to decreased stearoylation of TFRC (By similarity). Ubiquitination of MFN2 also takes place following induction of mitophagy; AMBRA1 acts as a cofactor for HUWE1-mediated ubiquitination (By similarity). Regulates neural differentiation and proliferation by catalyzing the polyubiquitination and degradation of MYCN (By similarity). May regulate abundance of CDC6 after DNA damage by polyubiquitinating and targeting CDC6 to degradation (By similarity). Mediates polyubiquitination of PA2G4 (By similarity). Acts in concert with MYCBP2 to regulate the circadian clock gene expression by promoting the lithium-induced ubiquitination and degradation of NR1D1 (By similarity). Binds to an upstream initiator-like sequence in the preprodynorphin gene (PubMed:7968380). Mediates HAPSTR1 degradation, but is also a required cofactor in the pathway by which HAPSTR1 governs stress signaling (By similarity). Acts as a regulator of the JNK and NF-kappa-B signaling pathways by mediating assembly of heterotypic 'Lys-63'-/'Lys-48'-linked branched ubiquitin chains that are then recognized by TAB2: HUWE1 mediates branching of 'Lys-48'-linked chains of substrates initially modified with 'Lys-63'-linked conjugates by TRAF6 (By similarity). 'Lys-63'-/'Lys-48'-linked branched ubiquitin chains protect 'Lys-63'-linkages from CYLD deubiquitination (By similarity). Ubiquitinates PPARA in hepatocytes (By similarity)., [UniProtKB, UniProtKB, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 6, "predicted_n_glycosites": 0, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 50, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 3, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "A0A8I6APS3", "ec_number_list": "2.3.2.26;2.3.2.32;2.3.2.31;2.3.2.23;2.3.2.27;2.3.2.34;2.3.2.24;5.2.1.8;2.3.2.-;2.3.2.25;1.1.1.205;3.2.1.23;3.5.4.5;2.3.2.5;3.6.4.13;2.4.1.25;3.2.1.33;4.2.99.18;5.6.2.4;4.1.2.4;2.4.1.186;3.5.4.6;3.1.1.47;2.7.1.35;3.4.22.1;1.11.1.6;2.5.1.18;4.1.2.13;3.6.5.-;4.2.1.24;3.2.1.31;2.4.1.1;2.7.10.2;2.7.11.1;2.7.1.40;1.13.11.-;1.13.11.34;3.4.19.1;2.3.3.8;1.16.3.1;2.7.4.6;2.7.13.3;3.4.23.5;5.4.2.11;5.4.2.4;2.7.1.1;3.3.2.6;3.4.11.4;2.7.1.11;5.3.2.1;5.3.3.12;3.4.21.46;3.1.6.4;2.4.2.7;5.4.2.2;1.1.1.42;3.6.4.6;3.4.24.35;3.1.6.12;3.6.4.10;2.7.11.24;2.4.2.1;3.4.22.52;3.4.22.27;2.7.11.39;5.3.1.9;5.1.3.-;3.5.1.23;3.5.1.-;3.6.1.6;3.4.25.1;3.4.18.1;1.11.1.24", "go_molecular_function": "GO:0003677 DNA binding;GO:0061630 ubiquitin protein ligase activity;GO:0034450 ubiquitin-ubiquitin ligase activity;GO:0004842 ubiquitin-protein transferase activity;GO:0140852 histone ubiquitin ligase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0030154 cell differentiation;GO:0006284 base-excision repair;GO:0043123 positive regulation of canonical NF-kappaB signal transduction;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0031398 positive regulation of protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P51593-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9QWG5-1", "uniprot_id": "INP4B_RAT", "mass": 105245.0, "length": 928, "protein_name": "Type II inositol 3,4-bisphosphate 4-phosphatase", "gene_name": "Inpp4b", "organism": "Rat", "refseq_name": "type II inositol 3,4-bisphosphate 4-phosphatase", "refseq_ac": "NP_446369", "gene_names_uniprotkb": "Inpp4b", "gene_names_refseq": "Inpp4b", "protein_names_uniprotkb": "Type II inositol 3,4-bisphosphate 4-phosphatase; 3.1.3.66; Inositol polyphosphate 4-phosphatase type II", "protein_names_refseq": "inositol polyphosphate 4-phosphatase type II; inositol polyphosphate-4-phosphatase, type II, 105kD; type II inositol 3,4-bisphosphate 4-phosphatase", "tax_id": 10116, "disease": "", "pathway": " (rno:116699); (R-RNO-1660499); (R-RNO-1660516); (R-RNO-1855183)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "9295334", "class_list": "", "function": "Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate and inositol 3,4-bisphosphate (PubMed:9295334). Plays a role in the late stages of macropinocytosis by dephosphorylating phosphatidylinositol 3,4-bisphosphate in membrane ruffles (By similarity). The lipid phosphatase activity is critical for tumor suppressor function. Antagonizes the PI3K-AKT/PKB signaling pathway by dephosphorylating phosphoinositides and thereby modulating cell cycle progression and cell survival (By similarity)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O35825", "ec_number_list": "3.1.3.66", "go_molecular_function": "GO:0034593 phosphatidylinositol bisphosphate phosphatase activity;GO:0017161 inositol-1,3,4-trisphosphate 4-phosphatase activity;GO:0052828 inositol-3,4-bisphosphate 4-phosphatase activity;GO:0008289 lipid binding;GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0051896 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0046822 regulation of nucleocytoplasmic transport;GO:0006874 intracellular calcium ion homeostasis;GO:0045671 negative regulation of osteoclast differentiation;GO:0046856 phosphatidylinositol dephosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9QWG5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LXZ0-1", "uniprot_id": "F1LXZ0_RAT", "mass": 20854.0, "length": 234, "protein_name": "Uncharacterized protein", "gene_name": "AABR07006049.1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "AABR07006049.1", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LXZ0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1M2Q5-1", "uniprot_id": "F1M2Q5_RAT", "mass": 193247.0, "length": 1695, "protein_name": "ATP-binding cassette, subfamily A (ABC1), member 14", "gene_name": "Abca14", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Abca14", "gene_names_refseq": "", "protein_names_uniprotkb": "ATP-binding cassette, subfamily A (ABC1), member 14", "protein_names_refseq": "", "tax_id": 10116, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041)", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "7.6.2.1;7.6.2.2;7.6.2.-", "go_molecular_function": "GO:0005319 lipid transporter activity;GO:0005524 ATP binding;GO:0042626 ATPase-coupled transmembrane transporter activity;GO:0016887 ATP hydrolysis activity;GO:0140359 ABC-type transporter activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0006869 lipid transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1M2Q5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "M0R8X9-1", "uniprot_id": "M0R8X9_RAT", "mass": 34825.0, "length": 326, "protein_name": "Tetraspanin-10", "gene_name": "Tspan10", "organism": "Rat", "refseq_name": "tetraspanin-10", "refseq_ac": "XP_003751041", "gene_names_uniprotkb": "Tspan10; LOC688308", "gene_names_refseq": "Tspan10", "protein_names_uniprotkb": "Tetraspanin-10; Oculospanin", "protein_names_refseq": "tetraspanin-10", "tax_id": 10116, "disease": "", "pathway": " (rno:688308)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Part of TspanC8 subgroup, composed of 6 members that interact with the transmembrane metalloprotease ADAM10. This interaction is required for ADAM10 exit from the endoplasmic reticulum and for enzymatic maturation and trafficking to the cell surface as well as substrate specificity. Different TspanC8/ADAM10 complexes have distinct substrates., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019899 enzyme binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0072594 establishment of protein localization to organelle;GO:0051604 protein maturation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R8X9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "M0R9X1-1", "uniprot_id": "M0R9X1_RAT", "mass": 125928.0, "length": 1123, "protein_name": "Probable ATP-dependent RNA helicase DHX34", "gene_name": "Dhx34", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Dhx34; LOC684903", "gene_names_refseq": "", "protein_names_uniprotkb": "Probable ATP-dependent RNA helicase DHX34; 3.6.4.13; DEAH box protein 34; DExH-box helicase 34", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:684903)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.6.2.3;3.6.4.13;3.6.4.12;2.7.11.1;3.6.1.5;3.6.4.10;3.6.4.-;2.3.2.27;5.6.2.4;3.6.5.-;5.6.2.-;3.1.-.-;2.7.7.7;2.7.7.49;3.1.13.1;4.2.99.18;7.6.2.2;7.6.2.3;7.6.2.-;5.6.1.6;7.2.2.-;3.6.1.15;3.6.4.6;3.1.3.1;3.9.1.1;6.1.1.12;3.6.1.-;2.7.4.3;3.1.4.-;3.4.24.-;3.6.-.-;3.4.21.53;5.6.2.5", "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0044877 protein-containing complex binding;GO:0004386 helicase activity", "go_cellular_component": "", "go_biological_process": "GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0042327 positive regulation of phosphorylation;GO:0000956 nuclear-transcribed mRNA catabolic process;GO:2000623 negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0R9X1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1M9P0-1", "uniprot_id": "F1M9P0_RAT", "mass": 45210.0, "length": 411, "protein_name": "Adaptor-related protein complex 1 associated regulatory protein", "gene_name": "Ap1ar", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Ap1ar", "gene_names_refseq": "", "protein_names_uniprotkb": "Adaptor-related protein complex 1 associated regulatory protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0035650 AP-1 adaptor complex binding;GO:0019894 kinesin binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005768 endosome;GO:0005794 Golgi apparatus;GO:0030133 transport vesicle", "go_biological_process": "GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation;GO:1900025 negative regulation of substrate adhesion-dependent cell spreading;GO:0048203 vesicle targeting, trans-Golgi to endosome;GO:2000146 negative regulation of cell motility;GO:0008104 intracellular protein localization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M9P0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A6I9-1", "uniprot_id": "D4A6I9_RAT", "mass": 156072.0, "length": 1429, "protein_name": "Mucin 6, oligomeric mucus/gel-forming", "gene_name": "Muc6", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Muc6", "gene_names_refseq": "", "protein_names_uniprotkb": "Mucin 6, oligomeric mucus/gel-forming", "protein_names_refseq": "", "tax_id": 10116, "disease": "gastric ulcer (Disease Ontology:DOID:10808); pancreatic cancer (Disease Ontology:DOID:1793); mucinous adenocarcinoma (Disease Ontology:DOID:3030); cholangiocarcinoma (Disease Ontology:DOID:4947)", "pathway": " (R-RNO-913709); (R-RNO-977068)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005201 extracellular matrix structural constituent", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A6I9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "M0RCV9-1", "uniprot_id": "M0RCV9_RAT", "mass": 35990.0, "length": 317, "protein_name": "Olfactory receptor", "gene_name": "Olr1049", "organism": "Rat", "refseq_name": "olfactory receptor 908", "refseq_ac": "NP_001001360", "gene_names_uniprotkb": "Olr1049; Olr908", "gene_names_refseq": "Olr1845; Olr908; Or6c202d", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1845; olfactory receptor 908; olfactory receptor Olr1845; olfactory receptor Olr908; olfactory receptor family 6 subfamily C member 202D; olfactory receptor gene Olr1845; olfactory receptor gene Olr908", "tax_id": 10116, "disease": "", "pathway": " (rno:288806); (rno:288840)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3ZQX7", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0RCV9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LY61-1", "uniprot_id": "F1LY61_RAT", "mass": 67969.0, "length": 592, "protein_name": "Phospholipase A2 group IVC", "gene_name": "Pla2g4c", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Pla2g4c; Pla2g4cl1", "gene_names_refseq": "", "protein_names_uniprotkb": "Phospholipase A2 group IVC", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:691810); (R-RNO-1482788); (R-RNO-1482839); (R-RNO-1482922); (R-RNO-1483115); (R-RNO-1483152)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.1.4;3.1.1.32;2.3.1.-;2.3.1.51;3.1.1.3;3.1.1.-;3.1.1.5;1.11.1.27;2.3.1.23;3.5.1.1;3.1.1.47;3.1.1.13;3.1.1.6;2.3.1.43;3.1.2.22;3.1.2.-;3.1.2.2", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0004623 phospholipase A2 activity;GO:0005544 calcium-dependent phospholipid binding;GO:0004622 phosphatidylcholine lysophospholipase activity;GO:0008374 O-acyltransferase activity", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005811 lipid droplet;GO:0005938 cell cortex", "go_biological_process": "GO:0046475 glycerophospholipid catabolic process;GO:0006663 platelet activating factor biosynthetic process;GO:0036152 phosphatidylethanolamine acyl-chain remodeling;GO:0036151 phosphatidylcholine acyl-chain remodeling;GO:0140042 lipid droplet formation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LY61-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LZV3-1", "uniprot_id": "F1LZV3_RAT", "mass": 98304.0, "length": 865, "protein_name": "Vomeronasal 2 receptor, 37", "gene_name": "Vom2r37", "organism": "Rat", "refseq_name": "vomeronasal 2 receptor, 37 isoform X2", "refseq_ac": "XP_038947382", "gene_names_uniprotkb": "Vom2r37", "gene_names_refseq": "Vom2r37", "protein_names_uniprotkb": "Vomeronasal 2 receptor, 37", "protein_names_refseq": "vomeronasal 2 receptor, 37 isoform X2", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LZV3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22449-1", "uniprot_id": "HNF4A_RAT", "mass": 52712.0, "length": 474, "protein_name": "Hepatocyte nuclear factor 4-alpha", "gene_name": "Hnf4a", "organism": "Rat", "refseq_name": "hepatocyte nuclear factor 4-alpha isoform 1", "refseq_ac": "NP_071516", "gene_names_uniprotkb": "Hnf4a; Hnf-4; Hnf4; Nr2a1; Tcf14", "gene_names_refseq": "Hnf4alpha; Hnf4a; Hnf4", "protein_names_uniprotkb": "Hepatocyte nuclear factor 4-alpha; HNF-4-alpha; Nuclear receptor subfamily 2 group A member 1; TCF-14; Transcription factor 14; Transcription factor HNF-4", "protein_names_refseq": "HNF-4-alpha; TCF-14; alpha transcription factor 4; hepatic nuclear factor 4, alpha; hepatocyte nuclear factor 4-alpha isoform 1; nuclear receptor subfamily 2 group A member 1; transcription factor 14; transcription factor HNF-4", "tax_id": 10116, "disease": "maturity-onset diabetes of the young (Disease Ontology:DOID:0050524); Fanconi renotubular syndrome 4 (Disease Ontology:DOID:0080760); autosomal dominant nonsyndromic deafness 5 (Disease Ontology:DOID:0110575); maturity-onset diabetes of the young type 1 (Disease Ontology:DOID:0111099); sensorineural hearing loss (Disease Ontology:DOID:10003); Fanconi syndrome (Disease Ontology:DOID:1062); familial combined hyperlipidemia (Disease Ontology:DOID:13809); alcohol use disorder (Disease Ontology:DOID:1574); glaucoma (Disease Ontology:DOID:1686); lung adenocarcinoma (Disease Ontology:DOID:3910); liver cirrhosis (Disease Ontology:DOID:5082); hepatocellular carcinoma (Disease Ontology:DOID:684); type 2 diabetes mellitus (Disease Ontology:DOID:9352); obesity (Disease Ontology:DOID:9970); hypoglycemia (Disease Ontology:DOID:9993)", "pathway": " (rno:25735); (R-RNO-383280)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "12193589;1610903;22673903;2279702;35879917;36988559;37338793;37528786;37993018;9234678", "class_list": "", "function": "HNF4A Negatively Regulated Posterior Capsular Opacification via Transcriptional Inhibition of MMP2., [RefSeq, PubMed]; Hsa-miR-34a-5p Ameliorates Hepatic Ischemia/Reperfusion Injury Via Targeting HNF4alpha., [RefSeq, PubMed]; Mechanism and Effect of HNF4alpha Decrease in a Rat Model of Cirrhosis and Liver Failure., [RefSeq, PubMed]; Targeted Activation of HNF4alpha by AMPK Inhibits Apoptosis and Ameliorates Neurological Injury Caused by Cardiac Arrest in Rats., [RefSeq, PubMed]; Transcriptional regulator which controls the expression of hepatic genes during the transition of endodermal cells to hepatic progenitor cells, facilitating the recruitment of RNA pol II to the promoters of target genes (By similarity). Activates the transcription of CYP2C38 (By similarity). Represses the CLOCK-BMAL1 transcriptional activity and is essential for circadian rhythm maintenance and period regulation in the liver and colon cells (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; [Combinational Overexpression of Foxa3 and Hnf4alpha Enhance the Proliferation and Prolong the Functional Maintenance of Primary Hepatocytes]., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 15, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A2ICG9", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0003700 DNA-binding transcription factor activity;GO:0005102 signaling receptor binding;GO:0005504 fatty acid binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0010470 regulation of gastrulation;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006629 lipid metabolic process;GO:0006637 acyl-CoA metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P22449-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P35745-1", "uniprot_id": "ACYP2_RAT", "mass": 10863.0, "length": 97, "protein_name": "Acylphosphatase-2", "gene_name": "Acyp2", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Acyp2; Acyp", "gene_names_refseq": "", "protein_names_uniprotkb": "Acylphosphatase-2; 3.6.1.7; Acylphosphatase, muscle type isozyme; Acylphosphate phosphohydrolase 2", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:364224)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "1647162;22673903", "class_list": "", "function": "catalyzes the hydrolysis of acylphosphates compounds containing a carboxylphosphate bond., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.1.7", "go_molecular_function": "GO:0042802 identical protein binding;GO:0003998 acylphosphatase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P35745-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8K1P9-1", "uniprot_id": "FADS3_RAT", "mass": 51467.0, "length": 449, "protein_name": "Fatty acid desaturase 3", "gene_name": "Fads3", "organism": "Rat", "refseq_name": "fatty acid desaturase 3", "refseq_ac": "NP_775160", "gene_names_uniprotkb": "Fads3", "gene_names_refseq": "Fads3", "protein_names_uniprotkb": "Fatty acid desaturase 3; 1.14.19.-; Delta(13) desaturase; Delta(13) fatty acid desaturase; trans-vaccenate Delta13-desaturase", "protein_names_refseq": "delta(13) desaturase; delta(13) fatty acid desaturase; fatty acid desaturase 3; putative fatty acid desaturase; trans-vaccenate Delta13-desaturase", "tax_id": 10116, "disease": "alcohol use disorder (Disease Ontology:DOID:1574); lipid metabolism disorder (Disease Ontology:DOID:3146)", "pathway": " (rno:286922)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "19752397;23966218;24070791;29393594;30262139", "class_list": "", "function": "FADS3 does exist under multiple protein isoforms depending on the mammalian tissues., [RefSeq, PubMed]; FADS3 is the first 'methyl-end' fatty acid desaturase functionally characterized in mammals, [RefSeq, PubMed]; FADS3 was secreted specifically by hepatocytes in the extracellular matrix where it was located on fibronectin-containing fibers.The 51 kDa FADS3 is secreted in the extracellular matrix of hepatocytes and blood., [RefSeq, PubMed]; Mammals have different sphingoid bases that differ in their length and/or pattern of desaturation and hydroxyl groups. The predominant sphingoid base that comprises mammalian ceramides is sphing-4-enine (sphingosine or SPH) which has a trans (E) desaturation at carbon 4. FADS3 is a desaturase that introduces a cis (Z) double bond between carbon 14 and carbon 15 of the sphingoid base (also known as long chain base, LCB), producing LCBs such as sphinga-4,14-dienine (SPD, d18:2(4E,14Z)) from SPH. Prefers SPH-containing ceramides (N-acylsphing-4-enines) as substrates. Capable of metabolizing also the SPH in its free form. SPD ceramides occur widely in mammalian tissues and cells. Due to their unusual structure containing a cis double bond, SPD ceramides may have an opposite, negative role in lipid microdomain formation relative to conventional ceramides. Could be involved in the detoxification of 1-deoxy sphingolipids, by desaturating the cytotoxic 1-deoxysphinganine (1-deoxySA, m18:0), produced under pathological conditions, to 1-deoxysphingenine (1-deoxysphingosine, 1-deoxySO, m18:1). Although prefers SPH-containing ceramides (N-acylsphing-4-enines) as substrates, it also exhibits activity toward dihydrosphingosine-containing CERs (N-acylsphinganines) and produces 14Z-SPH-containing sphingolipids. Its desaturase mechanism involves an electron transfer facilitated by cytochrome b5 (By similarity). FADS3 also acts as a methyl-end fatty acyl coenzyme A (CoA) desaturase that introduces a cis double bond between the preexisting double bond and the terminal methyl group of the fatty acyl chain. Desaturates (11E)-octadecenoate (trans-vaccenoate, the predominant trans fatty acid in human milk) at carbon 13 to generate (11E,13Z)-octadecadienoate (also known as conjugated linoleic acid 11E,13Z-CLA) (PubMed:24070791, PubMed:30262139)., [UniProtKB, PubMed, UniProtKB, PubMed]; Physiological evidence demonstrates the existence of in vivo synthesis of trans11,cis13-CLA from dietary trans-vaccenic acid in rodents; and establishes the FADS3 enzyme as a reliable mammalian trans-vaccenate Delta13-desaturase in vivo., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.14.19.-", "go_molecular_function": "GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water;GO:0016491 oxidoreductase activity", "go_cellular_component": "GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0006665 sphingolipid metabolic process;GO:0006636 unsaturated fatty acid biosynthetic process;GO:0010467 gene expression;GO:0006633 fatty acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q8K1P9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZMK9-1", "uniprot_id": "PRAG1_RAT", "mass": 147716.0, "length": 1368, "protein_name": "Inactive tyrosine-protein kinase PRAG1", "gene_name": "Prag1", "organism": "Rat", "refseq_name": "inactive tyrosine-protein kinase PRAG1", "refseq_ac": "NP_001100785", "gene_names_uniprotkb": "Prag1; Pragmin", "gene_names_refseq": "Prag1; Pragmin; RGD1311793", "protein_names_uniprotkb": "Inactive tyrosine-protein kinase PRAG1; PEAK1-related kinase-activating pseudokinase 1; Pragma of Rnd2", "protein_names_refseq": "inactive tyrosine-protein kinase PRAG1; pragma of Rnd2; tyrosine-protein kinase SgK223", "tax_id": 10116, "disease": "", "pathway": " (rno:306506); (R-RNO-9696270)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "16481321;21873224;22673903;27116701;29393594;29503074", "class_list": "", "function": "Catalytically inactive protein kinase that acts as a scaffold protein (PubMed:29503074). Functions as an effector of the small GTPase RND2, which stimulates RhoA activity and inhibits NGF-induced neurite outgrowth (PubMed:16481321). Promotes Src family kinase (SFK) signallig by regulating the subcellular localization of CSK, a negative regulator of these kinases, leading to the regulation of cell morphology and motility by a CSK-dependent mechanism (PubMed:21873224, PubMed:27116701). Acts as a critical coactivator of Notch signaling (By similarity)., [UniProtKB, UniProtKB, PubMed, PubMed, PubMed, PubMed]; Rnd2 regulates neurite outgrowth by functioning as the RhoA activator through pragmin, in contrast to Rnd1 and Rnd3 inhibiting RhoA signaling, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 10, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0042802 identical protein binding;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005925 focal adhesion", "go_biological_process": "GO:0016477 cell migration;GO:2000145 regulation of cell motility;GO:0010977 negative regulation of neuron projection development;GO:0035025 positive regulation of Rho protein signal transduction;GO:0008360 regulation of cell shape", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "D3ZMK9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P17220-1", "uniprot_id": "PSA2_RAT", "mass": 25927.0, "length": 234, "protein_name": "Proteasome subunit alpha type-2", "gene_name": "Psma2", "organism": "Rat", "refseq_name": "proteasome subunit alpha type-2", "refseq_ac": "NP_058975", "gene_names_uniprotkb": "Psma2", "gene_names_refseq": "Psma2", "protein_names_uniprotkb": "Proteasome subunit alpha type-2; Macropain subunit C3; Multicatalytic endopeptidase complex subunit C3; Proteasome component C3; Proteasome subunit alpha-2; alpha-2", "protein_names_refseq": "alpha-2; macropain subunit C3; multicatalytic endopeptidase complex subunit C3; proteasome (prosome, macropain) subunit, alpha type 2; proteasome alpha 2 subunit; proteasome component C3; proteasome subunit alpha 2; proteasome subunit alpha type-2", "tax_id": 10116, "disease": "", "pathway": " (rno:29669); (R-RNO-1169091); (R-RNO-1234176); (R-RNO-1236974); (R-RNO-1236978); (R-RNO-174084); (R-RNO-174113); (R-RNO-174154); (R-RNO-174178); (R-RNO-174184); (R-RNO-187577); (R-RNO-195253); (R-RNO-202424); (R-RNO-2467813); (R-RNO-2871837); (R-RNO-349425); (R-RNO-350562); (R-RNO-382556); (R-RNO-450408); (R-RNO-4608870); (R-RNO-4641257); (R-RNO-4641258); (R-RNO-5358346); (R-RNO-5607761); (R-RNO-5607764); (R-RNO-5610780); (R-RNO-5610785); (R-RNO-5632684); (R-RNO-5658442); (R-RNO-5668541); (R-RNO-5676590); (R-RNO-5687128); (R-RNO-5689603); (R-RNO-5689880); (R-RNO-6798695); (R-RNO-68867); (R-RNO-68949); (R-RNO-69017); (R-RNO-69481); (R-RNO-69601); (R-RNO-75815); (R-RNO-8852276); (R-RNO-8854050); (R-RNO-8939236); (R-RNO-8941858); (R-RNO-8948751); (R-RNO-8951664); (R-RNO-9020702); (R-RNO-9755511); (R-RNO-9762114); (R-RNO-9766229); (R-RNO-983168); (R-RNO-9907900); (R-RNO-9912633); (R-RNO-9929356); (R-RNO-9929491); (R-RNO-9931269); (R-RNO-9932298); (R-RNO-9954709)", "pathway_count": 59, "publication_count": 3, "publication_id_list": "2335242;2340272;8794741", "class_list": "", "function": "Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000932 P-body;GO:0008021 synaptic vesicle;GO:0000502 proteasome complex", "go_biological_process": "GO:0006979 response to oxidative stress;GO:0009615 response to virus;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0010498 proteasomal protein catabolic process;GO:0061136 regulation of proteasomal protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P17220-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O88831-1", "uniprot_id": "KKCC2_RAT", "mass": 64446.0, "length": 587, "protein_name": "Calcium/calmodulin-dependent protein kinase kinase 2", "gene_name": "Camkk2", "organism": "Rat", "refseq_name": "calcium/calmodulin-dependent protein kinase kinase 2 isoform 1", "refseq_ac": "NP_112628", "gene_names_uniprotkb": "Camkk2", "gene_names_refseq": "Camkk2", "protein_names_uniprotkb": "Calcium/calmodulin-dependent protein kinase kinase 2; 2.7.11.17; CaM-KK 2; CaM-KK beta; CaM-kinase kinase 2; CaM-kinase kinase beta; CaMKK 2; CaMKK beta; Calcium/calmodulin-dependent protein kinase kinase beta", "protein_names_refseq": "Ca+/Calmodulin-dependent protein kinase kinase beta (CaM-kinase kinase beta); CaM-kinase kinase beta; caM-KK 2; caM-KK beta; caM-kinase kinase 2; caMKK 2; caMKK beta; calcium/calmodulin-dependent protein kinase 2 beta; calcium/calmodulin-dependent protein kinase kinase 2 isoform 1; calcium/calmodulin-dependent protein kinase kinase 2, beta; calcium/calmodulin-dependent protein kinase kinase beta", "tax_id": 10116, "disease": "high grade glioma (Disease Ontology:DOID:3070)", "pathway": " (rno:83506); (R-RNO-111932); (R-RNO-442729); (R-RNO-9619229)", "pathway_count": 4, "publication_count": 11, "publication_id_list": "10651863;11264466;21807092;21957496;22673903;27151216;27791458;37338678;8631893;9276695;9822657", "class_list": "", "function": "CaMKK2 alleviates myocardial ischemia/reperfusion injury by inhibiting oxidative stress and inflammation via the action on the AMPK-AKT-GSK-3beta/Nrf2 signaling cascade., [RefSeq, PubMed]; Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1 and CAMK4. Phosphorylates CAMK1D (By similarity). Seems to be involved in hippocampal activation of CREB1 (By similarity). Efficiently phosphorylates 5'-AMP-activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca(2+) signals. May play a role in neurite growth. Isoform 2 may promote neurite elongation, while isoform 1 may promoter neurite branching., [UniProtKB, PubMed, PubMed, PubMed, PubMed]; Site-directed mutagenesis analysis revealed that Leu(358) in CaMKKbeta/Ile(322) in CaMKKalpha confer, at least in part, a distinct recognition of AMPK but not of CaMKIalpha., [RefSeq, PubMed]; The CAMKK2-MTOR pathway has a role in store-operated calcium entry-activated autophagy protection of endothelial progenitor cell proliferation in ox-LDL exposure, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.12.1;2.7.1.153;2.7.1.137;2.7.11.24;2.7.11.25;2.7.11.22;2.7.11.23;2.7.4.6;2.7.1.154;2.7.11.38;2.7.11.17;2.7.11.21;2.7.12.2;2.7.1.40;2.7.11.12;2.7.11.26;2.7.11.34;2.7.10.2;2.7.1.150;2.7.11.13;4.1.1.32;2.7.11.19;2.7.2.3;2.7.11.11;2.7.11.31;3.1.3.16;2.7.11.4;2.3.1.48;3.1.11.-;2.7.13.3;2.7.4.18;3.1.24.-;3.4.19.12;2.7.11.39;2.4.99.18;2.7.11.10", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0030295 protein kinase activator activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0043005 neuron projection;GO:0005737 cytoplasm", "go_biological_process": "GO:0006468 protein phosphorylation;GO:0032147 activation of protein kinase activity;GO:0046777 protein autophosphorylation;GO:0061762 CAMKK-AMPK signaling cascade;GO:1903599 positive regulation of autophagy of mitochondrion", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "O88831-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P28840-1", "uniprot_id": "NEC1_RAT", "mass": 84121.0, "length": 752, "protein_name": "Neuroendocrine convertase 1", "gene_name": "Pcsk1", "organism": "Rat", "refseq_name": "neuroendocrine convertase 1 precursor", "refseq_ac": "NP_058787", "gene_names_uniprotkb": "Pcsk1; Bdp; Nec-1; Nec1", "gene_names_refseq": "BDP; PC1; PC3; Pcsk1", "protein_names_uniprotkb": "Neuroendocrine convertase 1; 3.4.21.93; NEC 1; PC1; Prohormone convertase 1; Proprotein convertase 1", "protein_names_refseq": "NEC 1; Protein convertase subtilisin / kexin, type I; neuroendocrine convertase 1 precursor; neuroendocrine convertase 1; prohormone convertase 1; prohormone convertase 3; proprotein convertase 1", "tax_id": 10116, "disease": "proprotein convertase 1/3 deficiency (Disease Ontology:DOID:0111698); hypothyroidism (Disease Ontology:DOID:1459); islet cell tumor (Disease Ontology:DOID:1799); endocrine system disease (Disease Ontology:DOID:28); hyperglycemia (Disease Ontology:DOID:4195); hyperthyroidism (Disease Ontology:DOID:7998); type 2 diabetes mellitus (Disease Ontology:DOID:9352); obesity (Disease Ontology:DOID:9970)", "pathway": " (rno:25204); (R-RNO-209952); (R-RNO-422085)", "pathway_count": 3, "publication_count": 8, "publication_id_list": "1791845;1954888;19628676;23050949;23637853;26778167;29393594;9523585", "class_list": "", "function": "Chronic ethanol exposure decreases prohormone convertase (pc1/3) immunoreactivity in brain., [RefSeq, PubMed]; Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP., [UniProtKB, UniProtKB, UniProtKB, PubMed]; Macrophages from PC1/3 KO mice and rat PC1/3-KD NR8383 macrophages secreted more pro-inflammatory cytokines such as TNF-alpha, IL6, IL1alpha and CXCL2. Publication Status: Online-Only, [RefSeq, PubMed]; PC1/3 as an important regulator of vesicle trafficking and secretion in macrophages. Publication Status: Online-Only, [RefSeq, PubMed]; The presence of PC and GOAT in the cells, as well as n-octanoic acid in the culture medium, was necessary to produce n-octanoyl ghrelin., [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.4.21.93", "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0004252 serine-type endopeptidase activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane;GO:0030141 secretory granule;GO:0030425 dendrite;GO:0034774 secretory granule lumen", "go_biological_process": "GO:0010157 response to chlorate;GO:0016485 protein processing;GO:0016486 peptide hormone processing;GO:0032496 response to lipopolysaccharide;GO:0051592 response to calcium ion", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P28840-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P16310-1", "uniprot_id": "GHR_RAT", "mass": 71237.0, "length": 638, "protein_name": "Growth hormone receptor", "gene_name": "Ghr", "organism": "Rat", "refseq_name": "growth hormone receptor isoform 1 precursor", "refseq_ac": "NP_058790", "gene_names_uniprotkb": "Ghr", "gene_names_refseq": "GHR/BP; Ghr", "protein_names_uniprotkb": "Growth hormone receptor; GH receptor; Serum-binding protein; Somatotropin receptor", "protein_names_refseq": "GH receptor; growth hormone receptor isoform 1 precursor; growth hormone receptor variant d5-6; growth hormone receptor/binding protein; somatotropin receptor", "tax_id": 10116, "disease": "congenital hypothyroidism (Disease Ontology:DOID:0050328); autism spectrum disorder (Disease Ontology:DOID:0060041); isolated growth hormone deficiency (Disease Ontology:DOID:0060870); attention deficit hyperactivity disorder (Disease Ontology:DOID:1094); osteoporosis (Disease Ontology:DOID:11476); osteopetrosis (Disease Ontology:DOID:13533); familial hypercholesterolemia (Disease Ontology:DOID:13810); breast cancer (Disease Ontology:DOID:1612); colonic disease (Disease Ontology:DOID:5353); muscular atrophy (Disease Ontology:DOID:767); osteoarthritis (Disease Ontology:DOID:8398); type 2 diabetes mellitus (Disease Ontology:DOID:9352); Laron syndrome (Disease Ontology:DOID:9521); type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": " (rno:25235); (R-RNO-1170546); (R-RNO-982772)", "pathway_count": 3, "publication_count": 13, "publication_id_list": "10585430;10976913;11244571;1446642;21454685;24963636;2722883;2792761;7545168;7615519;8063815;8921876;9231797", "class_list": "", "function": "Receptor crosstalk between growth hormone and insulin signal in rats born small for gestational age with catch-up growth Publication Status: Online-Only, [RefSeq, PubMed]; Receptor for pituitary gland growth hormone (GH1) involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway., [UniProtKB, UniProtKB]; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth (PubMed:11244571). On ligand binding, couples to, and activates the JAK2/STAT5 pathway (PubMed:11244571, PubMed:9231797)., [UniProtKB, PubMed, PubMed]; The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling., [UniProtKB, UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 4, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 1, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 14, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "Q64236;Q80XW9", "ec_number_list": "", "go_molecular_function": "GO:0019838 growth factor binding;GO:0019901 protein kinase binding;GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity;GO:0008289 lipid binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0031623 receptor internalization;GO:0032869 cellular response to insulin stimulus;GO:0040014 regulation of multicellular organism growth;GO:0043410 positive regulation of MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P16310-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P02262-1", "uniprot_id": "H2A1_RAT", "mass": 14077.0, "length": 130, "protein_name": "Histone H2A type 1", "gene_name": "", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Histone H2A type 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "1268188", "class_list": "", "function": "Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0046982 protein heterodimerization activity;GO:0030527 structural constituent of chromatin", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0000786 nucleosome", "go_biological_process": "GO:0031507 heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P02262-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LYZ6-1", "uniprot_id": "F1LYZ6_RAT", "mass": 148505.0, "length": 1345, "protein_name": "snRNA-activating protein complex subunit 4", "gene_name": "Snapc4", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Snapc4", "gene_names_refseq": "", "protein_names_uniprotkb": "snRNA-activating protein complex subunit 4; snRNA-activating protein complex 190 kDa subunit", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:362088); (R-RNO-6807505); (R-RNO-76071)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0016251 RNA polymerase II general transcription initiation factor activity;GO:0001006 RNA polymerase III type 3 promoter sequence-specific DNA binding;GO:0000995 RNA polymerase III general transcription initiation factor activity", "go_cellular_component": "GO:0019185 snRNA-activating protein complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0042795 snRNA transcription by RNA polymerase II;GO:0042796 snRNA transcription by RNA polymerase III", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1LYZ6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1LXX8-1", "uniprot_id": "F1LXX8_RAT", "mass": 23224.0, "length": 194, "protein_name": "Spetex-2C protein", "gene_name": "Spetex2e", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Spetex2e; Spetex-2E; Spetex2c", "gene_names_refseq": "", "protein_names_uniprotkb": "Spetex-2C protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1LXX8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1M7J3-1", "uniprot_id": "F1M7J3_RAT", "mass": 96353.0, "length": 855, "protein_name": "G-protein coupled receptors family 3 profile domain-containing protein", "gene_name": "Vom2r61", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Vom2r61; Vom2r63", "gene_names_refseq": "", "protein_names_uniprotkb": "G-protein coupled receptors family 3 profile domain-containing protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1M7J3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "M0RCS2-1", "uniprot_id": "M0RCS2_RAT", "mass": 49614.0, "length": 442, "protein_name": "Transducin beta-like protein 2", "gene_name": "Tbl2", "organism": "Rat", "refseq_name": "transducin beta-like protein 2", "refseq_ac": "NP_001385844", "gene_names_uniprotkb": "Tbl2; LOC686610", "gene_names_refseq": "Tbl2", "protein_names_uniprotkb": "Transducin beta-like protein 2", "protein_names_refseq": "transducin beta-like protein 2", "tax_id": 10116, "disease": "", "pathway": " (rno:686610)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A096MJZ2", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding;GO:0051219 phosphoprotein binding;GO:0031369 translation initiation factor binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005829 cytosol", "go_biological_process": "GO:0071456 cellular response to hypoxia;GO:0042149 cellular response to glucose starvation;GO:0030968 endoplasmic reticulum unfolded protein response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "M0RCS2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D9I2F9-1", "uniprot_id": "NL1A1_RAT", "mass": 138392.0, "length": 1218, "protein_name": "NACHT, LRR and PYD domains-containing protein 1a allele 1", "gene_name": "Nlrp1a", "organism": "Rat", "refseq_name": "NACHT, LRR and PYD domains-containing protein 1a allele 1", "refseq_ac": "NP_001139227", "gene_names_uniprotkb": "Nlrp1a; Nlrp1", "gene_names_refseq": "Nalp1; Nlrp1a; Nlrp1", "protein_names_uniprotkb": "NACHT, LRR and PYD domains-containing protein 1a allele 1; 3.4.-.-", "protein_names_refseq": "NACHT, LRR and PYD domains-containing protein 1a allele 1; NACHT, LRR and PYD domains-containing protein 1a; NACHT, LRR and PYD domains-containing protein 1; NACHT, leucine rich repeat and PYD containing 1; NLR family protein 1; NLR family, pyrin domain containing 1; resistant anthrax lethal toxin", "tax_id": 10116, "disease": "vitiligo (Disease Ontology:DOID:12306)", "pathway": " (rno:360557); (R-RNO-844455)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "20502689;30120609;31383852;32558991;33731929;35951283;38976128", "class_list": "", "function": "Acts as the sensor component of the Nlrp1a inflammasome, which mediates inflammasome activation in response to various pathogen-associated signals, leading to subsequent pyroptosis (PubMed:33731929). Inflammasomes are supramolecular complexes that assemble in the cytosol in response to pathogens and other damage-associated signals and play critical roles in innate immunity and inflammation (By similarity). Acts as a recognition receptor (PRR): recognizes specific pathogens and other damage-associated signals, such as B.anthracis lethal toxin (LT) or Val-boroPro inhibitor, and mediates the formation of the inflammasome polymeric complex (PubMed:20502689, PubMed:31383852, PubMed:33731929). In response to pathogen-associated signals, the N-terminal part of Nlrp1a is degraded by the proteasome, releasing the cleaved C-terminal part of the protein (NACHT, LRR and PYD domains-containing protein 1a, C-terminus), which polymerizes to initiate the formation of the inflammasome complex: the inflammasome directly recruits pro-caspase-1 (proCASP1) independently of PYCARD/ASC and promotes caspase-1 (CASP1) activation, which subsequently cleaves and activates inflammatory cytokines IL1B and IL18 and gasdermin-D (GSDMD), leading to pyroptosis (By similarity). In the absence of GSDMD expression, the Nlrp1a inflammasome is able to recruit and activate CASP8, leading to activation of gasdermin-E (GSDME) (By similarity)., [UniProtKB, UniProtKB, PubMed, PubMed, UniProtKB, PubMed, UniProtKB]; Constitutes the active part of the Nlrp1a inflammasome (PubMed:33731929). In absence of pathogens and other damage-associated signals, interacts with the N-terminal part of Nlrp1a (NACHT, LRR and PYD domains-containing protein 1a, N-terminus), preventing activation of the Nlrp1a inflammasome. In response to pathogen-associated signals, the N-terminal part of Nlrp1a is degraded by the proteasome, releasing this form, which polymerizes to form the Nlrp1a inflammasome complex: the Nlrp1a inflammasome complex then directly recruits pro-caspase-1 (proCASP1) and promotes caspase-1 (CASP1) activation, leading to gasdermin-D (GSDMD) cleavage and subsequent pyroptosis., [UniProtKB, PubMed, UniProtKB]; Constitutes the active part of the Nlrp1a inflammasome. In absence of pathogens and other damage-associated signals, interacts with the N-terminal part of Nlrp1a (NACHT, LRR and PYD domains-containing protein 1a, N-terminus), preventing activation of the Nlrp1a inflammasome. In response to pathogen-associated signals, the N-terminal part of Nlrp1a is degraded by the proteasome, releasing this form, which polymerizes to form the Nlrp1a inflammasome complex: the Nlrp1a inflammasome complex then directly recruits pro-caspase-1 (proCASP1) and promotes caspase-1 (CASP1) activation, leading to gasdermin-D (GSDMD) cleavage and subsequent pyroptosis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Constitutes the precursor of the Nlrp1a inflammasome, which mediates autoproteolytic processing within the FIIND domain to generate the N-terminal and C-terminal parts, which are associated non-covalently in absence of pathogens and other damage-associated signals., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Inhibition of NLRP1-Dependent Pyroptosis Prevents Glycogen Synthase Kinase-3beta Overactivation-Induced Hyperphosphorylated Tau in Rats., [RefSeq, PubMed]; NLRP1 promoted myofibroblast differentiation and excessive ECM production in TGF-beta1-induced neonatal cardiac fibroblasts through directly targeting TGF-beta1/Smad signaling pathways., [RefSeq, PubMed]; Regulatory part that prevents formation of the Nlrp1a inflammasome: in absence of pathogens and other damage-associated signals, interacts with the C-terminal part of Nlrp1a (NACHT, LRR and PYD domains-containing protein 1a, C-terminus), preventing activation of the Nlrp1a inflammasome. In response to pathogen-associated signals, this part is ubiquitinated by the N-end rule pathway and degraded by the proteasome, releasing the cleaved C-terminal part of the protein, which polymerizes and forms the Nlrp1a inflammasome., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Structural and biochemical mechanisms of NLRP1 inhibition by DPP9., [RefSeq, PubMed]; Thioredoxin-1 Protects Neurons Through Inhibiting NLRP1-Mediated Neuronal Pyroptosis in Models of Alzheimer's Disease. Erratum:[Mol Neurobiol. 2025 May;62(5):6626. doi: 10.1007/s12035-024-04523-8. PMID: 39333348], [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A0G2QC28;F1LPA5", "ec_number_list": "3.4.-.-", "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0005524 ATP binding;GO:0019899 enzyme binding;GO:0019904 protein domain specific binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0043025 neuronal cell body;GO:0072558 NLRP1 inflammasome complex", "go_biological_process": "GO:0071493 cellular response to UV-B;GO:1904784 NLRP1 inflammasome complex assembly;GO:0006954 inflammatory response;GO:0007165 signal transduction;GO:0051260 protein homooligomerization", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "D9I2F9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZRP6-1", "uniprot_id": "AP1M2_RAT", "mass": 48167.0, "length": 423, "protein_name": "AP-1 complex subunit mu-2", "gene_name": "Ap1m2", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Ap1m2", "gene_names_refseq": "", "protein_names_uniprotkb": "AP-1 complex subunit mu-2; AP-mu chain family member mu1B; Adaptor protein complex AP-1 subunit mu-2; Adaptor-related protein complex 1 subunit mu-2; Clathrin assembly protein complex 1 mu-2 medium chain 2; Golgi adaptor HA1/AP1 adaptin mu-2 subunit; Mu-adaptin 2; Mu1B-adaptin", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-2132295); (R-RNO-432720); (R-RNO-432722)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15985462", "class_list": "", "function": "Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0035615 clathrin adaptor activity", "go_cellular_component": "GO:0005802 trans-Golgi network;GO:0030121 AP-1 adaptor complex;GO:0005794 Golgi apparatus;GO:0030665 clathrin-coated vesicle membrane;GO:0030131 clathrin adaptor complex", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006896 Golgi to vacuole transport;GO:0016192 vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZRP6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZU83-1", "uniprot_id": "D3ZU83_RAT", "mass": 49672.0, "length": 443, "protein_name": "Endoplasmic reticulum-Golgi intermediate compartment protein", "gene_name": "Ergic3", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Ergic3", "gene_names_refseq": "", "protein_names_uniprotkb": "Endoplasmic reticulum-Golgi intermediate compartment protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "lung adenocarcinoma (Disease Ontology:DOID:3910)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in transport between endoplasmic reticulum and Golgi., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005789 endoplasmic reticulum membrane;GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005783 endoplasmic reticulum;GO:0030134 COPII-coated ER to Golgi transport vesicle", "go_biological_process": "GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0090316 positive regulation of intracellular protein transport;GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZU83-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4ADC2-1", "uniprot_id": "D4ADC2_RAT", "mass": 334109.0, "length": 2967, "protein_name": "3'-5' exoribonuclease HELZ2", "gene_name": "Helz2", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Helz2; Pric285", "gene_names_refseq": "", "protein_names_uniprotkb": "3'-5' exoribonuclease HELZ2; 3.1.13.1; 3.6.4.13; ATP-dependent RNA helicase PRIC285; PPAR-gamma DNA-binding domain-interacting protein 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:296474)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Can degrade highly structured RNAs through its concerted ATP-dependent RNA helicase and 3' to 5' exoribonuclease activities. Shows a strong preference for pyrimidine over purine residues for its nuclease activity. Acts as a transcriptional coactivator for a number of nuclear receptors including PPARA, PPARG, THRA, THRB and RXRA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.6.2.3;3.6.4.13;3.6.4.12;2.7.11.1;3.6.1.5;3.6.4.10;3.6.4.-;2.3.2.27;5.6.2.4;3.6.5.-;5.6.2.-;3.1.-.-;2.7.7.7;2.7.7.49;3.1.13.1;4.2.99.18;7.6.2.2;7.6.2.3;7.6.2.-;5.6.1.6;7.2.2.-;3.6.1.15;3.6.4.6;3.1.3.1;3.9.1.1;6.1.1.12;3.6.1.-;2.7.4.3;3.1.4.-;3.4.24.-;3.6.-.-;3.4.21.53;5.6.2.5", "go_molecular_function": "GO:0008859 exoribonuclease II activity;GO:0003677 DNA binding;GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006974 DNA damage response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4ADC2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A3U1-1", "uniprot_id": "D4A3U1_RAT", "mass": 40595.0, "length": 369, "protein_name": "GTP-binding protein 10", "gene_name": "Gtpbp10", "organism": "Rat", "refseq_name": "GTP-binding protein 10", "refseq_ac": "NP_001094285", "gene_names_uniprotkb": "Gtpbp10", "gene_names_refseq": "Gtpbp10", "protein_names_uniprotkb": "GTP-binding protein 10", "protein_names_refseq": "GTP-binding protein 10 (putative); GTP-binding protein 10", "tax_id": 10116, "disease": "", "pathway": " (rno:312054)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0000287 magnesium ion binding;GO:0019843 rRNA binding;GO:0140978 mitochondrial large ribosomal subunit binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0042254 ribosome biogenesis;GO:1902775 mitochondrial large ribosomal subunit assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A3U1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZH30-1", "uniprot_id": "D3ZH30_RAT", "mass": 68658.0, "length": 597, "protein_name": "mRNA-capping enzyme", "gene_name": "Rngtt", "organism": "Rat", "refseq_name": "mRNA-capping enzyme", "refseq_ac": "NP_001101393", "gene_names_uniprotkb": "Rngtt", "gene_names_refseq": "Rngtt", "protein_names_uniprotkb": "mRNA-capping enzyme; GTP--RNA guanylyltransferase; GTase; mRNA 5'-phosphatase", "protein_names_refseq": "mRNA-capping enzyme", "tax_id": 10116, "disease": "", "pathway": " (rno:313131); (R-RNO-72086); (R-RNO-77075)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.7.50;3.6.1.74", "go_molecular_function": "GO:0005524 ATP binding;GO:0005525 GTP binding;GO:0004721 phosphoprotein phosphatase activity;GO:0004651 polynucleotide 5'-phosphatase activity;GO:0004484 mRNA guanylyltransferase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006370 7-methylguanosine mRNA capping;GO:0006396 RNA processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZH30-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZBH5-1", "uniprot_id": "D3ZBH5_RAT", "mass": 176482.0, "length": 1631, "protein_name": "Serine/threonine-protein kinase LMTK2", "gene_name": "Lmtk2", "organism": "Rat", "refseq_name": "serine/threonine-protein kinase LMTK2 precursor", "refseq_ac": "NP_001414165", "gene_names_uniprotkb": "Lmtk2", "gene_names_refseq": "Lmtk2", "protein_names_uniprotkb": "Serine/threonine-protein kinase LMTK2; 2.7.11.1; Brain-enriched kinase; Lemur tyrosine kinase 2", "protein_names_refseq": "serine/threonine-protein kinase LMTK2 precursor; serine/threonine-protein kinase LMTK2", "tax_id": 10116, "disease": "", "pathway": " (rno:304286)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Phosphorylates PPP1C, phosphorylase b and CFTR., [UniProtKB, UniProtKB]", "predicted_glycosites": 7, "predicted_n_glycosites": 0, "predicted_o_glycosites": 7, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 1, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.12.1;2.7.1.153;2.7.1.137;2.7.11.24;2.7.11.25;2.7.11.22;2.7.11.23;2.7.4.6;2.7.1.154;2.7.11.38;2.7.11.17;2.7.11.21;2.7.12.2;2.7.1.40;2.7.11.12;2.7.11.26;2.7.11.34;2.7.10.2;2.7.1.150;2.7.11.13;4.1.1.32;2.7.11.19;2.7.2.3;2.7.11.11;2.7.11.31;3.1.3.16;2.7.11.4;2.3.1.48;3.1.11.-;2.7.13.3;2.7.4.18;3.1.24.-;3.4.19.12;2.7.11.39;2.4.99.18;2.7.11.10", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004672 protein kinase activity;GO:0004864 protein phosphatase inhibitor activity;GO:0070853 myosin VI binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0012505 endomembrane system;GO:0005769 early endosome;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0006468 protein phosphorylation;GO:0046777 protein autophosphorylation;GO:0045022 early endosome to late endosome transport;GO:0018107 peptidyl-threonine phosphorylation;GO:0001881 receptor recycling", "synthesized_glycan_count": 0, "hit_score": 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Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher-order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53/TP53 at 'Lys-382', leading to repress p53/TP53-target genes. Plays a negative role in TGF-beta response regulation and a positive role in cell migration., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F7J138", "ec_number_list": "2.1.1.361;2.1.1.359;2.1.1.-;1.14.11.65;2.1.1.362;2.1.1.355;2.1.1.354", "go_molecular_function": "GO:0003714 transcription corepressor activity;GO:0042054 histone methyltransferase activity;GO:0016279 protein-lysine N-methyltransferase activity;GO:0042799 histone H4K20 methyltransferase activity;GO:0140944 histone H4K20 monomethyltransferase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0000785 chromatin;GO:0005634 nucleus;GO:0005694 chromosome;GO:0005700 polytene chromosome", "go_biological_process": "GO:2000042 negative regulation of double-strand break repair via homologous recombination;GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZEB9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2JWB6-1", "uniprot_id": "A0A0G2JWB6_RAT", "mass": 165396.0, "length": 1475, "protein_name": "Peroxidasin", "gene_name": "Pxdn", "organism": "Rat", "refseq_name": "peroxidasin homolog precursor", "refseq_ac": "NP_001258190", "gene_names_uniprotkb": "Pxdn", "gene_names_refseq": "Perc64; Pxdn; Vpo1", "protein_names_uniprotkb": "Peroxidasin", "protein_names_refseq": "PE responsive protein c64; melanoma-associated antigen MG50; peroxidasin homolog precursor; peroxidasin homolog", "tax_id": 10116, "disease": "anterior segment dysgenesis 7 (Disease Ontology:DOID:0080612)", "pathway": " (rno:554172); (R-RNO-2243919)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "21292788;24021280;27651140;29186367;31216444;36029851", "class_list": "", "function": "NOX/VPO1 pathway-derived reactive oxygen species promote the oxidative injury and dysfunctions of EPCs in PH, which may contribute to endothelial dysfunctions in PH, [RefSeq, PubMed]; The over-expression of VPO1 during the development of hypertension, accompanied by the endothelial dysfunction, the decreased NO levels, the elevated NOX and ROS activities, indicates a clear connection between VPO1 gene and hypertension.(VPO1), [RefSeq, PubMed]; VPO1 promotes cardiac remodeling by accelerating the Ang II-induced hypertrophy of H9c2 cell via the NOX2/VPO1/HOCl/ERK1/2 signaling pathways., [RefSeq, PubMed]; VPO1 promotes hypoxia-induced proliferation, apoptosis resistance, and migration in pulmonary artery smooth muscle cells via the NOX4/VPO1/HOCl/NF-kappaB signalling pathway., [RefSeq, PubMed]; Vascular peroxidase 1 promotes phenotypic transformation of pulmonary artery smooth muscle cells via ERK pathway in hypoxia-induced pulmonary hypertensive rats., [RefSeq, PubMed]; Vascular peroxidase 1/peroxidasin is a novel regulator of angiotensin II-induced vascular smooth muscle cell proliferation via NADPH oxidase-hydrogen peroxide pathways., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0016684 oxidoreductase activity, acting on peroxide as acceptor;GO:0005201 extracellular matrix structural constituent;GO:0004601 peroxidase activity", "go_cellular_component": "GO:0016020 membrane;GO:0005615 extracellular space;GO:0005783 endoplasmic reticulum;GO:0009986 cell surface;GO:0031012 extracellular matrix", "go_biological_process": "GO:0001525 angiogenesis;GO:0006979 response to oxidative stress;GO:0007155 cell adhesion;GO:0030198 extracellular matrix organization;GO:0051260 protein homooligomerization", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A0G2JWB6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A2W7-1", "uniprot_id": "D4A2W7_RAT", "mass": 160204.0, "length": 1465, "protein_name": "SET domain containing 5", "gene_name": "Setd5", "organism": "Rat", "refseq_name": "histone-lysine N-methyltransferase SETD5 isoform X3", "refseq_ac": "XP_063141936", "gene_names_uniprotkb": "Setd5", "gene_names_refseq": "RGD1310433; Setd5", "protein_names_uniprotkb": "SET domain containing 5", "protein_names_refseq": "histone-lysine N-methyltransferase SETD5 isoform X3", "tax_id": 10116, "disease": "autosomal dominant intellectual developmental disorder 23 (Disease Ontology:DOID:0070053); prostate cancer (Disease Ontology:DOID:10283); breast cancer (Disease Ontology:DOID:1612); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748)", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "16641100;22673903", "class_list": "", "function": "", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003714 transcription corepressor activity;GO:0046975 histone H3K36 methyltransferase activity;GO:0046974 histone H3K9 methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome;GO:0005654 nucleoplasm;GO:0000785 chromatin;GO:0000791 euchromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006325 chromatin organization;GO:0050890 cognition;GO:0006355 regulation of DNA-templated transcription;GO:0051963 regulation of synapse assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D4A2W7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A7A8-1", "uniprot_id": "D4A7A8_RAT", "mass": 22512.0, "length": 199, "protein_name": "Ras-related protein Rab-7b", "gene_name": "Rab7b", "organism": "Rat", "refseq_name": "ras-related protein Rab-7b", "refseq_ac": "NP_001102798", "gene_names_uniprotkb": "Rab7b", "gene_names_refseq": "RGD1562617; Rab7b", "protein_names_uniprotkb": "Ras-related protein Rab-7b", "protein_names_refseq": "ras-related protein Rab-7b", "tax_id": 10116, "disease": "", "pathway": " (rno:501854); (R-RNO-8854214); (R-RNO-8873719); (R-RNO-8876198)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "30911939", "class_list": "", "function": "Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Rab7b was upregulated in the rat brain following the transient middle cerebral artery occlusion. Overexpression of Rab7b in the brain by DNA transfection reduced cerebral infarction., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005525 GTP binding;GO:0003925 G protein activity;GO:0003924 GTPase activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005764 lysosome;GO:0005770 late endosome;GO:0045335 phagocytic vesicle;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0032755 positive regulation of interleukin-6 production;GO:0071346 cellular response to type II interferon;GO:0045654 positive regulation of megakaryocyte differentiation;GO:0034144 negative regulation of toll-like receptor 4 signaling pathway;GO:0034164 negative regulation of toll-like receptor 9 signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4A7A8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZEX6-1", "uniprot_id": "D3ZEX6_RAT", "mass": 51600.0, "length": 450, "protein_name": "Interferon regulatory factor 4", "gene_name": "Irf4", "organism": "Rat", "refseq_name": "interferon regulatory factor 4", "refseq_ac": "NP_001099578", "gene_names_uniprotkb": "Irf4", "gene_names_refseq": "Irf4", "protein_names_uniprotkb": "Interferon regulatory factor 4; Lymphocyte-specific interferon regulatory factor; NF-EM5", "protein_names_refseq": "interferon regulatory factor 4", "tax_id": 10116, "disease": "anaplastic large cell lymphoma (Disease Ontology:DOID:0050744); diffuse large B-cell lymphoma (Disease Ontology:DOID:0050745); peripheral T-cell lymphoma (Disease Ontology:DOID:0050749); follicular lymphoma (Disease Ontology:DOID:0050873); lymphoplasmacytic lymphoma (Disease Ontology:DOID:0060901); immunodeficiency 131 (Disease Ontology:DOID:0061125); pigmentation disease (Disease Ontology:DOID:10123); chronic lymphocytic leukemia (Disease Ontology:DOID:1040); leukemia (Disease Ontology:DOID:1240); dilated cardiomyopathy (Disease Ontology:DOID:12930); middle cerebral artery infarction (Disease Ontology:DOID:3525); multiple myeloma (Disease Ontology:DOID:9538); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (rno:291100)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "28851732;34628795", "class_list": "", "function": "Expression of interferon regulatory factor 4 and inflammation in secondary injury of intracerebral haemorrhage., [RefSeq, PubMed]; IRF4 protects arteries against neointima formation by promoting the expression of KLF4 by directly binding to its promoter., [RefSeq, PubMed]; Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 13, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0000976 transcription cis-regulatory region binding;GO:0003713 transcription coactivator activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0000786 nucleosome", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription;GO:0032736 positive regulation of interleukin-13 production;GO:0006338 chromatin remodeling", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZEX6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K2U9-1", "uniprot_id": "A0A0G2K2U9_RAT", "mass": 80447.0, "length": 733, "protein_name": "FYVE, RhoGEF and PH domain-containing protein 3", "gene_name": "Fgd3", "organism": "Rat", "refseq_name": "FYVE, RhoGEF and PH domain-containing protein 3", "refseq_ac": "XP_008769765", "gene_names_uniprotkb": "Fgd3", "gene_names_refseq": "Fgd3", "protein_names_uniprotkb": "FYVE, RhoGEF and PH domain-containing protein 3", "protein_names_refseq": "FYVE, RhoGEF and PH domain-containing protein 3", "tax_id": 10116, "disease": "Charcot-Marie-Tooth disease type 4H (Disease Ontology:DOID:0110192); Charcot-Marie-Tooth disease (Disease Ontology:DOID:10595); X-linked Aarskog syndrome (Disease Ontology:DOID:6683)", "pathway": " (rno:361223); (R-RNO-193648); (R-RNO-416482); (R-RNO-9013148)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "22673903;29393594", "class_list": "", "function": "Promotes the formation of filopodia. May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton", "go_biological_process": "GO:0046847 filopodium assembly;GO:0007010 cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A0G2K2U9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A0Z0-1", "uniprot_id": "D4A0Z0_RAT", "mass": 21239.0, "length": 188, "protein_name": "Phosphatidylinositol glycan anchor biosynthesis, class H", "gene_name": "Pigh", "organism": "Rat", "refseq_name": "phosphatidylinositol N-acetylglucosaminyltransferase subunit H isoform 1", "refseq_ac": "NP_001102184", "gene_names_uniprotkb": "Pigh", "gene_names_refseq": "Pigh", "protein_names_uniprotkb": "Phosphatidylinositol glycan anchor biosynthesis, class H", "protein_names_refseq": "phosphatidylinositol N-acetylglucosaminyltransferase subunit H isoform 1; phosphatidylinositol N-acetylglucosaminyltransferase subunit H; phosphatidylinositol glycan, class H", "tax_id": 10116, "disease": "", "pathway": " (rno:362756); (R-RNO-162710)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006506 GPI anchor biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A0Z0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4ADG4-1", "uniprot_id": "D4ADG4_RAT", "mass": 162646.0, "length": 1449, "protein_name": "MutL homolog 3", "gene_name": "Mlh3", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Mlh3", "gene_names_refseq": "", "protein_names_uniprotkb": "MutL homolog 3", "protein_names_refseq": "", "tax_id": 10116, "disease": "hereditary nonpolyposis colorectal cancer type 7 (Disease Ontology:DOID:0070276); endometrial cancer (Disease Ontology:DOID:1380); Lynch syndrome (Disease Ontology:DOID:3883); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (rno:314320)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0030983 mismatched DNA binding;GO:0140664 ATP-dependent DNA damage sensor activity;GO:0003682 chromatin binding", "go_cellular_component": "GO:0032300 mismatch repair complex;GO:0005712 chiasma;GO:0000794 condensed nuclear chromosome;GO:0000793 condensed chromosome;GO:0001673 male germ cell nucleus", "go_biological_process": "GO:0006298 mismatch repair;GO:0007144 female meiosis I;GO:0006974 DNA damage response;GO:0008104 intracellular protein localization;GO:0007130 synaptonemal complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4ADG4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2JT58-1", "uniprot_id": "A0A0G2JT58_RAT", "mass": 43838.0, "length": 393, "protein_name": "Short chain dehydrogenase/reductase family 42E, member 1", "gene_name": "Sdr42e1", "organism": "Rat", "refseq_name": "short-chain dehydrogenase/reductase family 42E member 1", "refseq_ac": "NP_001258198", "gene_names_uniprotkb": "Sdr42e1", "gene_names_refseq": "Hspc105; RGD1308481; Sdr42e1", "protein_names_uniprotkb": "Short chain dehydrogenase/reductase family 42E, member 1", "protein_names_refseq": "short-chain dehydrogenase/reductase family 42E member 1", "tax_id": 10116, "disease": "", "pathway": " (rno:307897)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006694 steroid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JT58-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZD36-1", "uniprot_id": "D3ZD36_RAT", "mass": 34577.0, "length": 307, "protein_name": "Ciliary associated calcium binding coiled-coil 1", "gene_name": "Cabcoco1", "organism": "Rat", "refseq_name": "ciliary-associated calcium-binding coiled-coil protein 1 isoform X1", "refseq_ac": "XP_006256417", "gene_names_uniprotkb": "Cabcoco1; RGD1306739", "gene_names_refseq": "Cabcoco1; RGD1306739", "protein_names_uniprotkb": "Ciliary associated calcium binding coiled-coil 1", "protein_names_refseq": "ciliary-associated calcium-binding coiled-coil protein 1 isoform X1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0036126 sperm flagellum", "go_biological_process": "GO:0120316 sperm flagellum assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZD36-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4A6W4-1", "uniprot_id": "D4A6W4_RAT", "mass": 60333.0, "length": 541, "protein_name": "Protein RFT1 homolog", "gene_name": "Rft1", "organism": "Rat", "refseq_name": "protein RFT1 homolog", "refseq_ac": "NP_001129338", "gene_names_uniprotkb": "Rft1", "gene_names_refseq": "RGD1562654; Rft1", "protein_names_uniprotkb": "Protein RFT1 homolog", "protein_names_refseq": "RFT1 homolog; protein RFT1 homolog", "tax_id": 10116, "disease": "congenital disorder of glycosylation type I (Disease Ontology:DOID:0050570); congenital disorder of glycosylation In (Disease Ontology:DOID:0080566); cancer (Disease Ontology:DOID:162)", "pathway": " (rno:290552)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Intramembrane glycolipid transporter that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. RFT1 could mediate the translocation of the cytosolically oriented intermediate DolPP-GlcNAc2Man5, produced by ALG11, into the ER lumen where dolichol-linked oligosaccharides assembly continues. However, the intramembrane lipid transporter activity could not be confirmed in vitro., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0034202 glycolipid floppase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006488 dolichol-linked oligosaccharide biosynthetic process;GO:0006487 protein N-linked glycosylation;GO:0034203 glycolipid translocation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D4A6W4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZLS5-1", "uniprot_id": "D3ZLS5_RAT", "mass": 289034.0, "length": 2610, "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "Hectd1", "organism": "Rat", "refseq_name": "E3 ubiquitin-protein ligase HECTD1 isoform 1", "refseq_ac": "NP_001406767", "gene_names_uniprotkb": "Hectd1", "gene_names_refseq": "Hectd1; RGD1561653", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase; 2.3.2.26", "protein_names_refseq": "E3 ubiquitin-protein ligase HECTD1 isoform 1; E3 ubiquitin-protein ligase HECTD1; HECT domain containing 1; HECT domain containing E3 ubiquitin protein ligase 1", "tax_id": 10116, "disease": "", "pathway": " (rno:362736)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "22673903;37096660", "class_list": "", "function": "CircHECTD1 promoted MIRI-associated inflammation via inhibiting miR-138-5p and upregulating ROCK2., [RefSeq, PubMed]; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0016607 nuclear speck", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0001779 natural killer cell differentiation;GO:0003170 heart valve development;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZLS5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D4ADE4-1", "uniprot_id": "D4ADE4_RAT", "mass": 142230.0, "length": 1260, "protein_name": "AT-rich interactive domain-containing protein 4A", "gene_name": "Arid4a", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Arid4a", "gene_names_refseq": "", "protein_names_uniprotkb": "AT-rich interactive domain-containing protein 4A; Retinoblastoma-binding protein 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "acute myeloid leukemia (Disease Ontology:DOID:9119)", "pathway": " (R-RNO-3214815)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "DNA-binding protein which modulates activity of several transcription factors including RB1 (retinoblastoma-associated protein) and AR (androgen receptor). May function as part of an mSin3A repressor complex. Has no intrinsic transcriptional activity. Plays a role in the regulation of epigenetic modifications at the PWS/AS imprinting center near the SNRPN promoter, where it might function as part of a complex with RB1 and ARID4B. Involved in spermatogenesis, together with ARID4B, where it acts as a transcriptional coactivator for AR and enhances expression of genes required for sperm maturation. Regulates expression of the tight junction protein CLDN3 in the testis, which is important for integrity of the blood-testis barrier. Plays a role in myeloid homeostasis where it regulates the histone methylation state of bone marrow cells and expression of various genes involved in hematopoiesis. May function as a leukemia suppressor., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0000976 transcription cis-regulatory region binding;GO:0003690 double-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0017053 transcription repressor complex", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0007283 spermatogenesis;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D4ADE4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZGX9-1", "uniprot_id": "D3ZGX9_RAT", "mass": 88497.0, "length": 785, "protein_name": "Semaphorin 3F", "gene_name": "Sema3f", "organism": "Rat", "refseq_name": "semaphorin-3F precursor", "refseq_ac": "NP_001400759", "gene_names_uniprotkb": "Sema3f", "gene_names_refseq": "Sema3f; SemaIV", "protein_names_uniprotkb": "Semaphorin 3F", "protein_names_refseq": "sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3 F; semaphorin IV; semaphorin-3F precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:315996)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "22977659;23063687;27309587", "class_list": "", "function": "Sema3F may contribute to the regulation of retinal ganglion cell function or survival., [RefSeq, PubMed]; These data reveal a novel mechanism by which Sema3F can induce hippocampal neuron growth cone collapse., [RefSeq, PubMed]; These results suggest that plexin A3 is expressed in OPCs and immature oligodendrocytes and is involved in OPC migration., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030215 semaphorin receptor binding;GO:0038191 neuropilin binding;GO:0045499 chemorepellent activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005576 extracellular region;GO:0005886 plasma membrane", "go_biological_process": "GO:0048731 system development;GO:0007165 signal transduction;GO:0120035 regulation of plasma membrane bounded cell projection organization;GO:0097490 sympathetic neuron projection extension;GO:0097491 sympathetic neuron projection guidance", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "D3ZGX9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZJV2-1", "uniprot_id": "D3ZJV2_RAT", "mass": 36799.0, "length": 330, "protein_name": "Cathepsin L-like 3", "gene_name": "Cts7l2; Ctsll3", "organism": "Rat", "refseq_name": "cathepsin L-like 3 precursor", "refseq_ac": "NP_001395605", "gene_names_uniprotkb": "Cts7l2; Ctsll3; Ctsll3; RGD1308751", "gene_names_refseq": "Ctsll3; RGD1560071", "protein_names_uniprotkb": "Cathepsin L-like 3", "protein_names_refseq": "cathepsin L-like 3 precursor; cathepsin L1; procathepsin L", "tax_id": 10116, "disease": "COVID-19 (Disease Ontology:DOID:0080600); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); alcohol use disorder (Disease Ontology:DOID:1574); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (rno:290981); (rno:498691)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004197 cysteine-type endopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005764 lysosome", "go_biological_process": "GO:0051603 proteolysis involved in protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZJV2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZKQ8-1", "uniprot_id": "D3ZKQ8_RAT", "mass": 109729.0, "length": 981, "protein_name": "Tumor necrosis factor receptor superfamily member 17", "gene_name": "Snx29; Tnfrsf17", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Snx29; Tnfrsf17; Snx29", "gene_names_refseq": "", "protein_names_uniprotkb": "Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "colon carcinoma (Disease Ontology:DOID:1520); multiple myeloma (Disease Ontology:DOID:9538)", "pathway": " (rno:287034); (rno:689142); (R-RNO-5669034)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0035091 phosphatidylinositol binding;GO:0038023 signaling receptor activity", "go_cellular_component": "", "go_biological_process": "GO:0002260 lymphocyte homeostasis;GO:0033209 tumor necrosis factor-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZKQ8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2JTC4-1", "uniprot_id": "A0A0G2JTC4_RAT", "mass": 8895.0, "length": 81, "protein_name": "Late cornified envelope 6A", "gene_name": "Lce6a", "organism": "Rat", "refseq_name": "late cornified envelope protein 6A", "refseq_ac": "NP_001386619", "gene_names_uniprotkb": "Lce6a", "gene_names_refseq": "Lce6a", "protein_names_uniprotkb": "Late cornified envelope 6A", "protein_names_refseq": "late cornified envelope protein 6A; rCG40941-like", "tax_id": 10116, "disease": "", "pathway": " (rno:100361652)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JTC4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2JTD4-1", "uniprot_id": "A0A0G2JTD4_RAT", "mass": 30185.0, "length": 264, "protein_name": "Y-linked testis-specific protein 1-like", "gene_name": "LOC134484268", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LOC134484268; LOC134478882; LOC134484257; LOC134484320; LOC134484376; LOC134484495", "gene_names_refseq": "", "protein_names_uniprotkb": "Y-linked testis-specific protein 1-like", "protein_names_refseq": "", "tax_id": 10116, 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Sbno2; Stno", "protein_names_uniprotkb": "Protein strawberry notch homolog 2", "protein_names_refseq": "protein strawberry notch homolog 2 isoform 1; protein strawberry notch homolog 2", "tax_id": 10116, "disease": "", "pathway": " (rno:314619)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a transcriptional coregulator, that can have both coactivator and corepressor functions. Inhibits the DCSTAMP-repressive activity of TAL1, hence enhancing the access of the transcription factor MITF to the DC-STAMP promoter in osteoclast. Plays a role in bone homeostasis; required as a positive regulator in TNFSF11//RANKL-mediated osteoclast fusion via a DCSTAMP-dependent pathway. May also be required in the regulation of osteoblast differentiation. Involved in the transcriptional corepression of NF-kappaB in macrophages. Plays a role as a regulator in the pro-inflammatory cascade., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0031490 chromatin DNA binding;GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0030316 osteoclast differentiation;GO:0061430 bone trabecula morphogenesis;GO:0071348 cellular response to interleukin-11;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2JZZ8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZRX1-1", "uniprot_id": "D3ZRX1_RAT", "mass": 70633.0, "length": 608, "protein_name": "Zinc finger protein 189", "gene_name": "Zfp189", "organism": "Rat", "refseq_name": "zinc finger protein 189", "refseq_ac": "NP_001101400", "gene_names_uniprotkb": "Zfp189", "gene_names_refseq": "Zfp189", "protein_names_uniprotkb": "Zinc finger protein 189", "protein_names_refseq": "zinc finger protein 189", "tax_id": 10116, "disease": "", "pathway": " (rno:313219); (R-RNO-212436)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZRX1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K0L2-1", "uniprot_id": "A0A0G2K0L2_RAT", "mass": 33488.0, "length": 303, "protein_name": "Olfactory receptor family 12 subfamily J member 2B", "gene_name": "Or12j2b", "organism": "Rat", "refseq_name": "olfactory receptor Olr298", "refseq_ac": "NP_001000235", "gene_names_uniprotkb": "Or12j2b", "gene_names_refseq": "Olr298; Or12j2b", "protein_names_uniprotkb": "Olfactory receptor family 12 subfamily J member 2B", "protein_names_refseq": "olfactory receptor 298; olfactory receptor Olr298; olfactory receptor gene Olr298", "tax_id": 10116, "disease": "", "pathway": " (rno:293597)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]; Possible taste receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K0L2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K0Q4-1", "uniprot_id": "A0A0G2K0Q4_RAT", "mass": 24769.0, "length": 216, "protein_name": "THAP domain containing 6", "gene_name": "Thap6", "organism": "Rat", "refseq_name": "THAP domain-containing protein 6", "refseq_ac": "NP_001100679", "gene_names_uniprotkb": "Thap6", "gene_names_refseq": "Thap6", "protein_names_uniprotkb": "THAP domain containing 6", "protein_names_refseq": "THAP domain-containing protein 6", "tax_id": 10116, "disease": "", "pathway": " (rno:305244)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0015630 microtubule cytoskeleton", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K0Q4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K0W3-1", "uniprot_id": "A0A0G2K0W3_RAT", "mass": 57961.0, "length": 526, "protein_name": "Protein tweety homolog", "gene_name": "Ttyh3", "organism": "Rat", "refseq_name": "protein tweety homolog 3 isoform X1", "refseq_ac": "XP_008767191", "gene_names_uniprotkb": "Ttyh3", "gene_names_refseq": "Ttyh3", "protein_names_uniprotkb": "Protein tweety homolog", "protein_names_refseq": "protein tweety homolog 3 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:304315); (R-RNO-2672351)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "22673903;38843836", "class_list": "", "function": "Probable chloride channel., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0072320 volume-sensitive chloride channel activity;GO:0005509 calcium ion binding;GO:0005229 intracellularly calcium-gated chloride channel activity;GO:0005254 chloride channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0034707 chloride channel complex", "go_biological_process": "GO:0006821 chloride transport;GO:0015813 L-glutamate transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A0G2K0W3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K1D2-1", "uniprot_id": "A0A0G2K1D2_RAT", "mass": 65945.0, "length": 607, "protein_name": "Rap1 GTPase-GDP dissociation stimulator 1", "gene_name": "Rap1gds1", "organism": "Rat", "refseq_name": "rap1 GTPase-GDP dissociation stimulator 1 isoform 1", "refseq_ac": "NP_001401991", "gene_names_uniprotkb": "Rap1gds1", "gene_names_refseq": "Rap1gds1", "protein_names_uniprotkb": "Rap1 GTPase-GDP dissociation stimulator 1", "protein_names_refseq": "RAP1, GTP-GDP dissociation stimulator 1; rap1 GTPase-GDP dissociation stimulator 1 isoform 1", "tax_id": 10116, "disease": "", "pathway": " (rno:310909)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "16954223;18348285;18683930;20190816;23155002", "class_list": "", "function": "ALK activation of Rap1 via the Rap1-specific GEF C3Gmay contribute to cell proliferation and oncogenesis of neuroblastoma., [RefSeq, PubMed]; Acts as a GEF (guanine nucleotide exchange factor) for prenylated RHOA. Acts as a GEF for RHOC. Chaperones the downstream trafficking and/or processing of small newly prenylated GTPases. Escorts RAC1 to the nucleus., [UniProtKB, UniProtKB]; Acts as a GEF (guanine nucleotide exchange factor) for the Rho family of small GTP-binding proteins (G proteins) that stimulates the dissociation of GDP to enable subsequent binding of GTP. Additionally, appears to chaperone the processing and/or trafficking of small GTPases containing a C-terminal polybasic region independently of GEF activity. Targets include RAP1A/RAP1B, RHOA, RHOB, RHOC, RAC1 and KRAS. Regulates mitochondrial dynamics by controlling RHOT function to promote mitochondrial fission during high calcium conditions. Able to promote the Ca(2+) release from the endoplasmic reticulum via both inositol trisphosphate (Ins3P) and ryanodine sensitive receptors leading to a enhanced mitochondrial Ca(2+) uptake., [UniProtKB, UniProtKB]; BetaPak-interacting exchange factor-mediated Rac1 activation requires smgGDS guanine nucleotide exchange factor in basic fibroblast growth factor-induced neurite outgrowth, [RefSeq, PubMed]; SmgGDS, a novel Ras regulator, suppresses Ras-BPGAP1-induced Ras/ERK activation., [RefSeq, PubMed]; These results identify SmgGDS as a novel regulator of myosin organization and contraction in vascular smooth muscle cells., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity;GO:0030695 GTPase regulator activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol", "go_biological_process": "GO:0031034 myosin filament assembly;GO:0043547 positive regulation of GTPase activity;GO:0003300 cardiac muscle hypertrophy;GO:0038166 angiotensin-activated signaling pathway;GO:0014829 vascular associated smooth muscle contraction", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A0A0G2K1D2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K1H6-1", "uniprot_id": "A0A0G2K1H6_RAT", "mass": 65211.0, "length": 556, "protein_name": "Zinc finger protein 939", "gene_name": "Zfp939", "organism": "Rat", "refseq_name": "zinc finger protein OZF-like isoform X1", "refseq_ac": "XP_006228993", "gene_names_uniprotkb": "Zfp939", "gene_names_refseq": "Zfp939", "protein_names_uniprotkb": "Zinc finger protein 939", "protein_names_refseq": "zinc finger protein OZF-like isoform X1", "tax_id": 10116, "disease": "", "pathway": " (rno:690136)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K1H6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K2J0-1", "uniprot_id": "A0A0G2K2J0_RAT", "mass": 75792.0, "length": 668, "protein_name": "SHC SH2 domain-binding protein 1", "gene_name": "Shcbp1", "organism": "Rat", "refseq_name": "SHC SH2 domain-binding protein 1", "refseq_ac": "NP_001386144", "gene_names_uniprotkb": "Shcbp1", "gene_names_refseq": "Shcbp1", "protein_names_uniprotkb": "SHC SH2 domain-binding protein 1", "protein_names_refseq": "SHC SH2 domain-binding protein 1; Shc SH2-domain binding protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:364648)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May play a role in signaling pathways governing cellular proliferation, cell growth and differentiation. May be a component of a novel signaling pathway downstream of Shc. Acts as a positive regulator of FGF signaling in neural progenitor cells., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, 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"gene_name": "Stx11", "organism": "Rat", "refseq_name": "syntaxin-11", "refseq_ac": "NP_001020809", "gene_names_uniprotkb": "Stx11", "gene_names_refseq": "Stx11", "protein_names_uniprotkb": "Syntaxin-11", "protein_names_refseq": "syntaxin-11", "tax_id": 10116, "disease": "familial hemophagocytic lymphohistiocytosis 4 (Disease Ontology:DOID:0110924)", "pathway": " (rno:292483)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, 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phagocytic vesicle", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0043312 neutrophil degranulation;GO:0071346 cellular response to type II interferon;GO:0006887 exocytosis;GO:0001913 T cell mediated cytotoxicity", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K516-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K574-1", "uniprot_id": "A0A0G2K574_RAT", "mass": 16560.0, "length": 150, "protein_name": "Ig-like domain-containing protein", "gene_name": "AABR07017639.2", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "AABR07017639.2; ENSRNOG00000064043", "gene_names_refseq": "", "protein_names_uniprotkb": "Ig-like domain-containing protein", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, 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"binding_glycan_count": 0, "secondary_ac_list": "A0A8I6B6H6", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0042101 T cell receptor complex", "go_biological_process": "GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K574-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K603-1", "uniprot_id": "A0A0G2K603_RAT", "mass": 56440.0, "length": 490, "protein_name": "Angiopoietin-like 1", "gene_name": "Angptl1", "organism": "Rat", "refseq_name": "angiopoietin-related protein 1 precursor", "refseq_ac": "NP_001389285", "gene_names_uniprotkb": "Angptl1", "gene_names_refseq": "Angptl1", "protein_names_uniprotkb": "Angiopoietin-like 1", "protein_names_refseq": "angiopoietin-related protein 1 precursor; angiopoietin-related protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:679942)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "19786610", "class_list": "", 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"reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix;GO:0005576 extracellular region", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0007596 blood coagulation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K603-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K677-1", "uniprot_id": "A0A0G2K677_RAT", "mass": 293380.0, "length": 2609, "protein_name": "Spectrin, beta, non-erythrocytic 4", "gene_name": "Sptbn4", "organism": "Rat", "refseq_name": "spectrin beta chain, non-erythrocytic 4 isoform X1", "refseq_ac": "XP_008757363", 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"go_biological_process": "GO:0007409 axonogenesis;GO:0007528 neuromuscular junction development;GO:0009566 fertilization;GO:0030534 adult behavior;GO:0050905 neuromuscular process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0G2K677-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0G2K8S2-1", "uniprot_id": "A0A0G2K8S2_RAT", "mass": 35823.0, "length": 333, "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "Gapdhl10", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Gapdhl10; RGD1564958", "gene_names_refseq": "", "protein_names_uniprotkb": "Glyceraldehyde-3-phosphate dehydrogenase; 1.2.1.12", "protein_names_refseq": "", "tax_id": 10116, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); lymphangioleiomyomatosis (Disease Ontology:DOID:3319)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, 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"glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.2.1.12;2.6.99.-", "go_molecular_function": "GO:0051287 NAD binding;GO:0016740 transferase activity;GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity;GO:0050661 NADP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005856 cytoskeleton", "go_biological_process": "GO:0006417 regulation of translation;GO:0006915 apoptotic process;GO:0006006 glucose metabolic process;GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0G2K8S2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0U1RRV5-1", "uniprot_id": "A0A0U1RRV5_RAT", "mass": 151166.0, "length": 1349, "protein_name": "Clustered mitochondria protein homolog", "gene_name": "Cluh", "organism": "Rat", "refseq_name": "clustered mitochondria protein homolog", "refseq_ac": "NP_001292142", "gene_names_uniprotkb": "Cluh", "gene_names_refseq": "Cluh; RGD1307222", "protein_names_uniprotkb": "Clustered mitochondria protein homolog", "protein_names_refseq": "clustered mitochondria (cluA/CLU1) homolog; clustered mitochondria homolog; clustered mitochondria protein homolog", "tax_id": 10116, "disease": "", "pathway": " (rno:303300)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis., [UniProtKB, HAMAP, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0007005 mitochondrion organization;GO:0048312 intracellular distribution of mitochondria", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A0U1RRV5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0U1RS05-1", "uniprot_id": "A0A0U1RS05_RAT", "mass": 110388.0, "length": 956, "protein_name": "Toll-like receptor 13", "gene_name": "Tlr13", "organism": "Rat", "refseq_name": "toll-like receptor 13 precursor", "refseq_ac": "NP_001395788", "gene_names_uniprotkb": "Tlr13", "gene_names_refseq": "AABR07039446.2; RGD1562655; Tlr13", "protein_names_uniprotkb": "Toll-like receptor 13", "protein_names_refseq": "toll-like receptor 13 precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:317227)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0006954 inflammatory response;GO:0007165 signal transduction;GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A0U1RS05-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A140UHY3-1", "uniprot_id": "A0A140UHY3_RAT", "mass": 68993.0, "length": 662, "protein_name": "RNA-binding protein EWS", "gene_name": "Ewsr1", "organism": "Rat", "refseq_name": "RNA-binding protein EWS isoform X1", "refseq_ac": "XP_006251263", "gene_names_uniprotkb": "Ewsr1", "gene_names_refseq": "Ewsr1", "protein_names_uniprotkb": "RNA-binding protein EWS", "protein_names_refseq": "RNA-binding protein EWS isoform X1", "tax_id": 10116, "disease": "amyotrophic lateral sclerosis type 6 (Disease Ontology:DOID:0060198); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); Ewing sarcoma (Disease Ontology:DOID:3369); frontotemporal dementia (Disease Ontology:DOID:9255)", "pathway": " (rno:289752)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A0G2JWK8", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0005516 calmodulin binding;GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0015030 Cajal body", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140UHY3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A1W2Q672-1", "uniprot_id": "A0A1W2Q672_RAT", "mass": 40157.0, "length": 348, "protein_name": "Bis(monoacylglycero)phosphate synthase CLN5", "gene_name": "Cln5", "organism": "Rat", "refseq_name": "ceroid-lipofuscinosis neuronal protein 5 isoform X1", "refseq_ac": "XP_038949328", "gene_names_uniprotkb": "Cln5; AABR07008608.1; AABR07019209.2", "gene_names_refseq": "Cln5", "protein_names_uniprotkb": "Bis(monoacylglycero)phosphate synthase CLN5; 3.1.2.22; Ceroid-lipofuscinosis neuronal protein 5; Palmitoyl protein thioesterase CLN5; S-depalmitoylase CLN5", "protein_names_refseq": "ceroid-lipofuscinosis neuronal protein 5 isoform X1", "tax_id": 10116, "disease": "neuronal ceroid lipofuscinosis 5 (Disease Ontology:DOID:0110728)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the synthesis of bis(monoacylglycero)phosphate (BMP) via transacylation of 2 molecules of lysophosphatidylglycerol (LPG). BMP also known as lysobisphosphatidic acid plays a key role in the formation of intraluminal vesicles and in maintaining intracellular cholesterol homeostasis. Can use only LPG as the exclusive lysophospholipid acyl donor for base exchange and displays BMP synthase activity towards various LPGs (LPG 14:0, LPG 16:0, LPG 18:0, LPG 18:1) with a higher preference for longer chain lengths. Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane., [UniProtKB, UniProtKB, UniProtKB]; Exhibits palmitoyl protein thioesterase (S-depalmitoylation) activity in vitro and most likely plays a role in protein S-depalmitoylation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.2.22;2.3.1.21;3.1.2.2;3.1.2.-;3.4.-.-;3.1.1.93;3.4.19.12", "go_molecular_function": "GO:0005537 D-mannose binding;GO:0016798 hydrolase activity, acting on glycosyl bonds;GO:0008474 palmitoyl-(protein) hydrolase activity;GO:0052816 long-chain fatty acyl-CoA hydrolase activity;GO:0160121 bis(monoacylglycero)phosphate synthase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0016020 membrane;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0007420 brain development;GO:0007601 visual perception;GO:0007040 lysosome organization;GO:0042147 retrograde transport, endosome to Golgi;GO:0022008 neurogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A1W2Q672-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B0BN78-1", "uniprot_id": "B0BN78_RAT", "mass": 34820.0, "length": 319, "protein_name": "Mitochondrial ornithine transporter 1", "gene_name": "Taf7", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Taf7", "gene_names_refseq": "", "protein_names_uniprotkb": "Mitochondrial ornithine transporter 1; Solute carrier family 25 member 15", "protein_names_refseq": "", "tax_id": 10116, "disease": "oligospermia (Disease Ontology:DOID:14228)", "pathway": " (rno:307485); (R-RNO-674695); (R-RNO-6804756); (R-RNO-73776); (R-RNO-73779); (R-RNO-75953); (R-RNO-76042)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mitochondrial ornithine-citrulline antiporter. Catalyzes the exchange between cytosolic ornithine and mitochondrial citrulline plus an H(+), the proton compensates the positive charge of ornithine thus leading to an electroneutral transport. Plays a crucial role in the urea cycle, by connecting the cytosolic and the intramitochondrial reactions of the urea cycle. Lysine and arginine are also transported by the antiport mechanism. In addition, catalyzes an electroneutral exchange of ornithine or lysine for H(+), a reaction driven by the pH gradient across the inner membrane., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000064 L-ornithine transmembrane transporter activity;GO:0046982 protein heterodimerization activity;GO:0000976 transcription cis-regulatory region binding;GO:0046966 nuclear thyroid hormone receptor binding;GO:0015189 L-lysine transmembrane transporter activity", "go_cellular_component": "GO:0033276 transcription factor TFTC complex;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005743 mitochondrial inner membrane;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0006591 ornithine metabolic process;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B0BN78-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B0K017-1", "uniprot_id": "B0K017_RAT", "mass": 39375.0, "length": 370, "protein_name": "ADP-ribosylhydrolase ARH3", "gene_name": "Adprs", "organism": "Rat", "refseq_name": "ADP-ribosylhydrolase ARH3", "refseq_ac": "NP_001102150", "gene_names_uniprotkb": "Adprs; Adprhl2", "gene_names_refseq": "Adprhl2; Adprs", "protein_names_uniprotkb": "ADP-ribosylhydrolase ARH3; 3.2.1.143; ADP-ribose glycohydrolase ARH3; ADP-ribosylhydrolase 3; O-acetyl-ADP-ribose deacetylase ARH3; Poly(ADP-ribose) glycohydrolase ARH3; [Protein ADP-ribosylarginine] hydrolase-like protein 2; [Protein ADP-ribosylserine] hydrolase", "protein_names_refseq": "ADP-ribose glycohydrolase ARH3; ADP-ribosylhydrolase ARH3; ADP-ribosylhydrolase like 2; poly(ADP-ribose) glycohydrolase ARH3", "tax_id": 10116, "disease": "stress-induced childhood-onset neurodegeneration with variable ataxia and seizures (Disease Ontology:DOID:0070352)", "pathway": " (rno:362600); (R-RNO-110362)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.2.1.143;3.2.2.19;3.2.2.-;3.1.1.106", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004649 poly(ADP-ribose) glycohydrolase activity;GO:0061463 O-acetyl-ADP-ribose deacetylase activity;GO:0140292 ADP-ribosylserine hydrolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006281 DNA repair;GO:0060546 negative regulation of necroptotic process;GO:0071451 cellular response to superoxide;GO:0140290 peptidyl-serine ADP-deribosylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B0K017-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B0K032-1", "uniprot_id": "B0K032_RAT", "mass": 19652.0, "length": 173, "protein_name": "Protein tyrosine phosphatase type IVA 3", "gene_name": "Ptp4a3", "organism": "Rat", "refseq_name": "protein tyrosine phosphatase type IVA 3", "refseq_ac": "NP_001107877", "gene_names_uniprotkb": "Ptp4a3", "gene_names_refseq": "Ptp4a3", "protein_names_uniprotkb": "Protein tyrosine phosphatase type IVA 3; 3.1.3.48; Protein-tyrosine phosphatase 4a3; Protein-tyrosine phosphatase of regenerating liver 3", "protein_names_refseq": "protein tyrosine phosphatase type IVA 3; protein tyrosine phosphatase type IVA, member 3", "tax_id": 10116, "disease": "", "pathway": " (rno:362930)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "17018620", "class_list": "", "function": "PRL-3 protein is expressed in fetal heart, developing blood vessels, and pre-erythrocytes but not in their mature counterparts., [RefSeq, PubMed]; Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.3.48;2.7.10.1;3.1.3.16;3.1.3.2;3.1.3.21;3.1.3.18;3.1.3.67;3.1.3.-;3.1.3.27;3.1.3.5", "go_molecular_function": "GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005769 early endosome;GO:0005886 plasma membrane", "go_biological_process": "GO:0007219 Notch signaling pathway;GO:1990830 cellular response to leukemia inhibitory factor;GO:0043542 endothelial cell migration;GO:0043117 positive regulation of vascular permeability;GO:1900746 regulation of vascular endothelial growth factor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "B0K032-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B1H257-1", "uniprot_id": "B1H257_RAT", "mass": 22176.0, "length": 195, "protein_name": "BLOC-1-related complex subunit 5", "gene_name": "Borcs5", "organism": "Rat", "refseq_name": "BLOC-1-related complex subunit 5", "refseq_ac": "NP_001102120", "gene_names_uniprotkb": "Borcs5; Loh12cr1", "gene_names_refseq": "Borcs5; Loh12cr1", "protein_names_uniprotkb": "BLOC-1-related complex subunit 5", "protein_names_refseq": "BLOC-1-related complex subunit 5; loss of heterozygosity, 12, chromosomal region 1", "tax_id": 10116, "disease": "colorectal adenocarcinoma (Disease Ontology:DOID:0050861)", "pathway": " (rno:362452)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane;GO:0030424 axon;GO:0005764 lysosome;GO:0030672 synaptic vesicle membrane;GO:0098574 cytoplasmic side of lysosomal membrane", "go_biological_process": "GO:0007399 nervous system development;GO:0007005 mitochondrion organization;GO:0032418 lysosome localization;GO:0072384 organelle transport along microtubule;GO:0061564 axon development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "B1H257-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B1H2A2-1", "uniprot_id": "B1H2A2_RAT", "mass": 55627.0, "length": 496, "protein_name": "Fibronectin type III and SPRY domain-containing protein 1", "gene_name": "Fsd1", "organism": "Rat", "refseq_name": "fibronectin type III and SPRY domain-containing protein 1", "refseq_ac": "NP_001425422", "gene_names_uniprotkb": "Fsd1", "gene_names_refseq": "Fsd1l1; Fsd1", "protein_names_uniprotkb": "Fibronectin type III and SPRY domain-containing protein 1", "protein_names_refseq": "fibronectin type 3 and SPRY domain-containing protein-like1; fibronectin type 3 and SPRY domain-containing protein; fibronectin type III and SPRY domain-containing protein 1", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "May be involved in microtubule organization and stabilization., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "M0R7H8", "ec_number_list": "", "go_molecular_function": "GO:0008017 microtubule binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0005829 cytosol;GO:0005874 microtubule;GO:0032154 cleavage furrow", "go_biological_process": "GO:0051301 cell division;GO:0060236 regulation of mitotic spindle organization;GO:0032465 regulation of cytokinesis;GO:0031122 cytoplasmic microtubule organization;GO:0051302 regulation of cell division", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "B1H2A2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B1PLB1-1", "uniprot_id": "B1PLB1_RAT", "mass": 35489.0, "length": 329, "protein_name": "CD34 molecule", "gene_name": "Cd34", "organism": "Rat", "refseq_name": "hematopoietic progenitor cell antigen CD34 isoform 2", "refseq_ac": "NP_001399676", "gene_names_uniprotkb": "Cd34", "gene_names_refseq": "Cd34", "protein_names_uniprotkb": "CD34 molecule", "protein_names_refseq": "CD34 antigen; hematopoietic progenitor cell antigen CD34 isoform 2; hematopoietic progenitor cell antigen CD34", "tax_id": 10116, "disease": "thyroid gland carcinoma (Disease Ontology:DOID:3963); diabetic retinopathy (Disease Ontology:DOID:8947)", "pathway": " (rno:305081); (R-RNO-198933)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "22673903;26271978;31395804;34052675", "class_list": "", "function": "Data show that the synovial angiogenesis is associated with the over-expressions of hypoxia inducible factor 1alpha (HIF-1alpha), vascular endothelial growth factor (VEGF) and CD34 antigen in adjuvant arthritis., [RefSeq, PubMed]; This study reports an increased number and proliferation of CD34+ cells in SOD1G93A rat spinal cord during paralysis progression. Publication Status: Online-Only, [RefSeq, PubMed]; Ultrastructural aberrations, histological disruption and upregulation of the VEGF, CD34 and ASMA immunoexpression in the myocardium of anemic albino rats., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "B1PLB2", "ec_number_list": "", "go_molecular_function": "GO:0030246 carbohydrate binding;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding;GO:0043199 sulfate binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0016020 membrane", "go_biological_process": "GO:0032703 negative regulation of interleukin-2 production;GO:0007165 signal transduction;GO:0010628 positive regulation of gene expression;GO:0010629 negative regulation of gene expression;GO:0001894 tissue homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "B1PLB1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B1WBR8-1", "uniprot_id": "B1WBR8_RAT", "mass": 70159.0, "length": 621, "protein_name": "F-box/LRR-repeat protein 4", "gene_name": "Fbxl4", "organism": "Rat", "refseq_name": "F-box/LRR-repeat protein 4 isoform 1", "refseq_ac": "NP_001382505", "gene_names_uniprotkb": "Fbxl4", "gene_names_refseq": "Fbxl4", "protein_names_uniprotkb": "F-box/LRR-repeat protein 4; F-box and leucine-rich repeat protein 4", "protein_names_refseq": "F-box/LRR-repeat protein 4 isoform 1; F-box/LRR-repeat protein 4", "tax_id": 10116, "disease": "mitochondrial DNA depletion syndrome 13 (Disease Ontology:DOID:0080131)", "pathway": " (rno:313101); (R-RNO-8951664); (R-RNO-983168)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:1990756 ubiquitin-like ligase-substrate adaptor activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005758 mitochondrial intermembrane space;GO:0016607 nuclear speck;GO:0019005 SCF ubiquitin ligase complex;GO:0005634 nucleus", "go_biological_process": "GO:1901525 negative regulation of mitophagy;GO:0000422 autophagy of mitochondrion;GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B1WBR8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B1WBX4-1", "uniprot_id": "B1WBX4_RAT", "mass": 52861.0, "length": 461, "protein_name": "Zinc finger protein 2", "gene_name": "Zfp2", "organism": "Rat", "refseq_name": "zinc finger protein ZFP2", "refseq_ac": "NP_001121030", "gene_names_uniprotkb": "Zfp2", "gene_names_refseq": "Mkr-2; Mkr2; Zfp2", "protein_names_uniprotkb": "Zinc finger protein 2", "protein_names_refseq": "multifinger protein mKr2; zinc finger protein 2 homolog; zinc finger protein 879-like; zinc finger protein ZFP2", "tax_id": 10116, "disease": "", "pathway": " (rno:497897)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B1WBX4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B1WBY7-1", "uniprot_id": "B1WBY7_RAT", "mass": 45884.0, "length": 413, "protein_name": "Erlin-1", "gene_name": "Erlin1", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Erlin1", "gene_names_refseq": "", "protein_names_uniprotkb": "Erlin-1; Endoplasmic reticulum lipid raft-associated protein 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "hereditary spastic paraplegia 62 (Disease Ontology:DOID:0110813); hereditary spastic paraplegia (Disease Ontology:DOID:2476)", "pathway": " (rno:293939); (R-RNO-382556); (R-RNO-9931269)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding;GO:0015485 cholesterol binding;GO:0008289 lipid binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0032991 protein-containing complex", "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0045717 negative regulation of fatty acid biosynthetic process;GO:0045540 regulation of cholesterol biosynthetic process;GO:0036503 ERAD pathway;GO:0045541 negative regulation of cholesterol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B1WBY7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B1WC69-1", "uniprot_id": "B1WC69_RAT", "mass": 52309.0, "length": 476, "protein_name": "NOP2/Sun RNA methyltransferase 6", "gene_name": "Nsun6", "organism": "Rat", "refseq_name": "tRNA (cytosine(72)-C(5))-methyltransferase NSUN6", "refseq_ac": "NP_001100837", "gene_names_uniprotkb": "Nsun6", "gene_names_refseq": "Nopd1; Nsun6", "protein_names_uniprotkb": "NOP2/Sun RNA methyltransferase 6", "protein_names_refseq": "NOL1/NOP2/Sun domain family, member 6; NOP2/Sun RNA methyltransferase family member 6; nucleolar protein (NOL1/NOP2/sun) and PUA domains 1; putative methyltransferase NSUN6; tRNA (cytosine(72)-C(5))-methyltransferase NSUN6", "tax_id": 10116, "disease": "syndromic intellectual disability (Disease Ontology:DOID:0050888); autosomal recessive intellectual developmental disorder 82 (Disease Ontology:DOID:0060947)", "pathway": " (rno:307148)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016428 tRNA (cytidine-5-)-methyltransferase activity;GO:0000049 tRNA binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0002946 tRNA C5-cytosine methylation;GO:0006400 tRNA modification;GO:0030488 tRNA methylation;GO:0001510 RNA methylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B1WC69-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B1WC73-1", "uniprot_id": "B1WC73_RAT", "mass": 20968.0, "length": 186, "protein_name": "ADP-ribosylation factor-like protein 6", "gene_name": "Arl6", "organism": "Rat", "refseq_name": "ADP-ribosylation factor-like protein 6 isoform 1", "refseq_ac": "NP_001430583", "gene_names_uniprotkb": "Arl6", "gene_names_refseq": "Arl6", "protein_names_uniprotkb": "ADP-ribosylation factor-like protein 6", "protein_names_refseq": "ADP-ribosylation factor like GTPase 6; ADP-ribosylation factor-like 6; ADP-ribosylation factor-like protein 6 isoform 1; ADP-ribosylation factor-like protein 6", "tax_id": 10116, "disease": "ciliopathy (Disease Ontology:DOID:0060340); Bardet-Biedl syndrome 1 (Disease Ontology:DOID:0110123); Bardet-Biedl syndrome 3 (Disease Ontology:DOID:0110125); retinitis pigmentosa 55 (Disease Ontology:DOID:0110370); Bardet-Biedl syndrome (Disease Ontology:DOID:1935)", "pathway": " (R-RNO-5620922)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F7F983", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005930 axoneme;GO:0060170 ciliary membrane;GO:0005829 cytosol;GO:0005929 cilium", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0060271 cilium assembly;GO:0016192 vesicle-mediated transport;GO:0061512 protein localization to cilium;GO:0030030 cell projection organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B1WC73-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B2GV55-1", "uniprot_id": "B2GV55_RAT", "mass": 46173.0, "length": 422, "protein_name": "E2 ubiquitin-conjugating enzyme", "gene_name": "Ube2q1", "organism": "Rat", "refseq_name": "ubiquitin-conjugating enzyme E2 Q1", "refseq_ac": "NP_001099918", "gene_names_uniprotkb": "Ube2q1", "gene_names_refseq": "Ube2q1; Ube2q", "protein_names_uniprotkb": "E2 ubiquitin-conjugating enzyme; 2.3.2.23", "protein_names_refseq": "ubiquitin-conjugating enzyme E2 Q1; ubiquitin-conjugating enzyme E2Q (putative) 1; ubiquitin-conjugating enzyme E2Q family member 1", "tax_id": 10116, "disease": "", "pathway": " (rno:295252); (R-RNO-983168)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "24166684", "class_list": "", "function": "UBE2Q1 might play an important role in the neuropathological process of traumatic brain injury through modulating p53 signaling., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.2.26;2.3.2.32;2.3.2.31;2.3.2.23;2.3.2.27;2.3.2.34;2.3.2.24;2.3.2.-;2.3.2.25;6.2.1.45;6.2.1.64", "go_molecular_function": "GO:0005524 ATP binding;GO:0061631 ubiquitin conjugating enzyme activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0001967 suckling behavior;GO:0007617 mating behavior;GO:0009566 fertilization;GO:0000209 protein polyubiquitination;GO:0070459 prolactin secretion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "B2GV55-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B2RYC8-1", "uniprot_id": "B2RYC8_RAT", "mass": 68977.0, "length": 610, "protein_name": "Interleukin-1 receptor-associated kinase 3", "gene_name": "Irak3", "organism": "Rat", "refseq_name": "interleukin-1 receptor-associated kinase 3", "refseq_ac": "NP_001101571", "gene_names_uniprotkb": "Irak3", "gene_names_refseq": "Irak3", "protein_names_uniprotkb": "Interleukin-1 receptor-associated kinase 3; IL-1 receptor-associated kinase M; Inactive IL-1 receptor-associated kinase 3", "protein_names_refseq": "interleukin-1 receptor-associated kinase 3", "tax_id": 10116, "disease": "osteoporosis (Disease Ontology:DOID:11476); asthma (Disease Ontology:DOID:2841); tuberculosis (Disease Ontology:DOID:399); melioidosis (Disease Ontology:DOID:5052); type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": " (rno:314870); (R-RNO-9020702)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "34757596", "class_list": "", "function": "MiR-539-5p inhibits the inflammatory injury in septic H9c2 cells by regulating IRAK3., [RefSeq, PubMed]; Putative inactive protein kinase which regulates signaling downstream of immune receptors including IL1R and Toll-like receptors. Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex. Upon IL33-induced lung inflammation, positively regulates expression of IL6, CSF3, CXCL2 and CCL5 mRNAs in dendritic cells., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0019901 protein kinase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0001960 negative regulation of cytokine-mediated signaling pathway;GO:0070498 interleukin-1-mediated signaling pathway;GO:0006468 protein phosphorylation;GO:0032496 response to lipopolysaccharide;GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "B2RYC8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B2RYE0-1", "uniprot_id": "B2RYE0_RAT", "mass": 37554.0, "length": 337, "protein_name": "SAM pointed domain-containing Ets transcription factor", "gene_name": "Spdef", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Spdef", "gene_names_refseq": "", "protein_names_uniprotkb": "SAM pointed domain-containing Ets transcription factor; Prostate epithelium-specific Ets transcription factor; Prostate-derived Ets factor", "protein_names_refseq": "", "tax_id": 10116, "disease": "ovarian cancer (Disease Ontology:DOID:2394)", "pathway": " (rno:689210)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May function as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter. Binds to 5'-GGAT-3' DNA sequences. May play a role in the regulation of the prostate gland and/or prostate cancer development. Acts as a transcriptional activator for SERPINB5 promoter., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding;GO:1990837 sequence-specific double-stranded DNA binding;GO:0003700 DNA-binding transcription factor activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0010454 negative regulation of cell fate commitment;GO:0010455 positive regulation of cell fate commitment;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B2RYE0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B2RYS2-1", "uniprot_id": "B2RYS2_RAT", "mass": 13388.0, "length": 109, "protein_name": "Cytochrome b-c1 complex subunit 7", "gene_name": "Uqcrb", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Uqcrb; Uqcrbl1", "gene_names_refseq": "", "protein_names_uniprotkb": "Cytochrome b-c1 complex subunit 7", "protein_names_refseq": "", "tax_id": 10116, "disease": "mitochondrial complex III deficiency nuclear type 3 (Disease Ontology:DOID:0080112); depressive disorder (Disease Ontology:DOID:1596); inherited metabolic disorder (Disease Ontology:DOID:655)", "pathway": " (rno:362897); (R-RNO-611105); (R-RNO-9865881)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0045275 respiratory chain complex III", "go_biological_process": "GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B2RYS2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B2RZ27-1", "uniprot_id": "SH3L3_RAT", "mass": 10477.0, "length": 93, "protein_name": "SH3 domain-binding glutamic acid-rich-like protein 3", "gene_name": "Sh3bgrl3", "organism": "Rat", "refseq_name": "SH3 domain-binding glutamic acid-rich-like protein 3", "refseq_ac": "NP_001100158", "gene_names_uniprotkb": "Sh3bgrl3; rCG_30780", "gene_names_refseq": "Sh3bgrl3; TIP-B1", "protein_names_uniprotkb": "SH3 domain-binding glutamic acid-rich-like protein 3; TIP-B1; TNF inhibitory protein B1", "protein_names_refseq": "SH3 domain binding glutamic acid-rich protein-like 3; SH3 domain-binding glutamic acid-rich-like protein 3; TNF inhibitory protein B1", "tax_id": 10116, "disease": "", "pathway": " (rno:298544)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "11404387;17974098", "class_list": "", "function": "Could act as a modulator of glutaredoxin biological activity (By similarity). May play a role in cytoskeleton organization (By similarity)., [UniProtKB, UniProtKB]; Could act as a modulator of glutaredoxin biological activity. May play a role in cytoskeleton organization., [UniProtKB, UniProtKB]; Nickel(II) treatment down-regulated Sh3bgrl3 expression., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0032587 ruffle membrane", "go_biological_process": "GO:0007010 cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "B2RZ27-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B2RZ54-1", "uniprot_id": "B2RZ54_RAT", "mass": 22883.0, "length": 209, "protein_name": "Cd7 molecule", "gene_name": "Cd7", "organism": "Rat", "refseq_name": "T-cell antigen CD7 precursor", "refseq_ac": "NP_001100544", "gene_names_uniprotkb": "Cd7", "gene_names_refseq": "Cd7", "protein_names_uniprotkb": "Cd7 molecule", "protein_names_refseq": "CD7 antigen; T-cell antigen CD7 precursor; T-cell antigen CD7", "tax_id": 10116, "disease": "", "pathway": " (rno:303747)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0048873 homeostasis of number of cells within a tissue;GO:0002250 adaptive immune response;GO:0002726 positive regulation of T cell cytokine production", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B2RZ54-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B5DEX8-1", "uniprot_id": "B5DEX8_RAT", "mass": 25527.0, "length": 217, "protein_name": "MOB kinase activator 3A", "gene_name": "Mob3a", "organism": "Rat", "refseq_name": "MOB kinase activator 3A", "refseq_ac": "NP_001102204", "gene_names_uniprotkb": "Mob3a", "gene_names_refseq": "Mob3a; Mobkl2a; Mobkl2b", "protein_names_uniprotkb": "MOB kinase activator 3A", "protein_names_refseq": "MOB kinase activator 3A; MOB1, Mps One Binder kinase activator-like 2A; MOB1, Mps One Binder kinase activator-like 2B; mps one binder kinase activator-like 2A", "tax_id": 10116, "disease": "", "pathway": " (rno:362833)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0030295 protein kinase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B5DEX8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B5DF80-1", "uniprot_id": "B5DF80_RAT", "mass": 71029.0, "length": 643, "protein_name": "Polyadenylate-binding protein", "gene_name": "Pabpc6", "organism": "Rat", "refseq_name": "poly(A) binding protein, cytoplasmic 6", "refseq_ac": "NP_001099678", "gene_names_uniprotkb": "Pabpc6", "gene_names_refseq": "Pabpc3; Pabpc6", "protein_names_uniprotkb": "Polyadenylate-binding protein; PABP", "protein_names_refseq": "poly(A) binding protein, cytoplasmic 3; poly(A) binding protein, cytoplasmic 6", "tax_id": 10116, "disease": "", "pathway": " (rno:292295)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Binds the poly(A) tail of mRNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003730 mRNA 3'-UTR binding;GO:0008143 poly(A) binding;GO:0008266 poly(U) RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0030027 lamellipodium;GO:0005681 spliceosomal complex;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0008380 RNA splicing;GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "B5DF80-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B5DFF4-1", "uniprot_id": "B5DFF4_RAT", "mass": 38441.0, "length": 353, "protein_name": "VPS37C subunit of ESCRT-I", "gene_name": "Vps37c", "organism": "Rat", "refseq_name": "vacuolar protein sorting-associated protein 37C isoform 1", "refseq_ac": "NP_001383921", "gene_names_uniprotkb": "Vps37c; NEWGENE_1309258", "gene_names_refseq": "RGD1309258; Vps37c", "protein_names_uniprotkb": "VPS37C subunit of ESCRT-I", "protein_names_refseq": "VPS37C, ESCRT-I subunit; vacuolar protein sorting 37 homolog C; vacuolar protein sorting 37C; vacuolar protein sorting-associated protein 37C isoform 1; vacuolar protein sorting-associated protein 37C", "tax_id": 10116, "disease": "", "pathway": " (rno:108348178); (R-RNO-917729)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation., [UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0048306 calcium-dependent protein binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0031902 late endosome membrane;GO:0000813 ESCRT I complex", "go_biological_process": "GO:0036258 multivesicular body assembly;GO:0039702 viral budding via host ESCRT complex;GO:0006612 protein targeting to membrane;GO:0016236 macroautophagy;GO:0006623 protein targeting to vacuole", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B5DFF4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B5DFJ0-1", "uniprot_id": "B5DFJ0_RAT", "mass": 68379.0, "length": 635, "protein_name": "Solute carrier family 7, member 4", "gene_name": "Slc7a4", "organism": "Rat", "refseq_name": "cationic amino acid transporter 4", "refseq_ac": "NP_001100548", "gene_names_uniprotkb": "Slc7a4", "gene_names_refseq": "Slc7a4", "protein_names_uniprotkb": "Solute carrier family 7, member 4", "protein_names_refseq": "cationic amino acid transporter 4; solute carrier family 7 (cationic amino acid transporter, y+ system), member 4; solute carrier family 7 (orphan transporter), member 4", "tax_id": 10116, "disease": "", "pathway": " (rno:303787)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015171 amino acid transmembrane transporter activity;GO:0046943 carboxylic acid transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0006865 amino acid transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B5DFJ0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B5DFJ4-1", "uniprot_id": "B5DFJ4_RAT", "mass": 110186.0, "length": 973, "protein_name": "Vacuolar protein sorting-associated protein 18 homolog", "gene_name": "Vps18", "organism": "Rat", "refseq_name": "vacuolar protein sorting-associated protein 18 homolog", "refseq_ac": "NP_001099969", "gene_names_uniprotkb": "Vps18", "gene_names_refseq": "Vps18", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 18 homolog", "protein_names_refseq": "VPS18 CORVET/HOPS core subunit; vacuolar protein sorting 18 homolog; vacuolar protein sorting-associated protein 18 homolog", "tax_id": 10116, "disease": "cholestasis (Disease Ontology:DOID:13580)", "pathway": " (rno:296083)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0008270 zinc ion binding;GO:0030674 protein-macromolecule adaptor activity;GO:0019905 syntaxin binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0030897 HOPS complex;GO:0005768 endosome;GO:0005769 early endosome;GO:0005884 actin filament", "go_biological_process": "GO:0048284 organelle fusion;GO:0006886 intracellular protein transport;GO:0007032 endosome organization;GO:0007040 lysosome organization;GO:0008333 endosome to lysosome transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B5DFJ4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "C0H5Y5-1", "uniprot_id": "C0H5Y5_RAT", "mass": 55059.0, "length": 480, "protein_name": "CASP8 and FADD-like apoptosis regulator", "gene_name": "Cflar", "organism": "Rat", "refseq_name": "CASP8 and FADD-like apoptosis regulator isoform 1", "refseq_ac": "NP_001029036", "gene_names_uniprotkb": "Cflar", "gene_names_refseq": "Cflar; Flip", "protein_names_uniprotkb": "CASP8 and FADD-like apoptosis regulator", "protein_names_refseq": "CASP8 and FADD-like apoptosis regulator isoform 1", "tax_id": 10116, "disease": "idiopathic pulmonary fibrosis (Disease Ontology:DOID:0050156); myelodysplastic syndrome (Disease Ontology:DOID:0050908); congestive heart failure (Disease Ontology:DOID:6000); acute myeloid leukemia (Disease Ontology:DOID:9119)", "pathway": " (rno:117279); (R-RNO-3371378); (R-RNO-5218900); (R-RNO-5357905); (R-RNO-69416); (R-RNO-75158)", "pathway_count": 6, "publication_count": 4, "publication_id_list": "11925448;24691542;26566102;28498469", "class_list": "", "function": "Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity., [UniProtKB, UniProtKB]; C-FLIP expression was significantly decreased in organs of septic rats compared with control rats, and that c-FLIP overexpression protected HUVECs from LPS+CHX-induced apoptosis in vitro., [RefSeq, PubMed]; Estradiol increased c-FLIPlong expression in anterior pituitary cells but not in GH3 cells., [RefSeq, PubMed]; Notch3 signaling in vascular smooth muscle cells induces c-FLIP expression via ERK/MAPK activation, [RefSeq, PubMed]; Our results also suggest that emodin regulates cFLIP expression in transcriptional level. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0002020 protease binding;GO:0008047 enzyme activator activity;GO:0016504 peptidase activator activity;GO:0044877 protein-containing complex binding;GO:0004197 cysteine-type endopeptidase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0031265 CD95 death-inducing signaling complex", "go_biological_process": "GO:0014866 skeletal myofibril assembly;GO:0043403 skeletal muscle tissue regeneration;GO:0072126 positive regulation of glomerular mesangial cell proliferation;GO:1901740 negative regulation of myoblast fusion;GO:1903055 positive regulation of extracellular matrix organization", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "C0H5Y5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3Z7Z5-1", "uniprot_id": "D3Z7Z5_RAT", "mass": 79491.0, "length": 734, "protein_name": "RAN binding protein 10", "gene_name": "Ranbp10", "organism": "Rat", "refseq_name": "ran-binding protein 10 isoform X1", "refseq_ac": "XP_017456806", "gene_names_uniprotkb": "Ranbp10", "gene_names_refseq": "RGD1311587; Ranbp10", "protein_names_uniprotkb": "RAN binding protein 10", "protein_names_refseq": "ran-binding protein 10 isoform X1", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-8851805)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0031267 small GTPase binding;GO:0048487 beta-tubulin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0015630 microtubule cytoskeleton;GO:0000151 ubiquitin ligase complex;GO:0034657 GID complex", "go_biological_process": "GO:0007010 cytoskeleton organization;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0000226 microtubule cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3Z7Z5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3Z837-1", "uniprot_id": "D3Z837_RAT", "mass": 172934.0, "length": 1557, "protein_name": "Serine/threonine-protein kinase MRCK gamma", "gene_name": "Cdc42bpg", "organism": "Rat", "refseq_name": "serine/threonine-protein kinase MRCK gamma isoform X2", "refseq_ac": "XP_038964412", "gene_names_uniprotkb": "Cdc42bpg", "gene_names_refseq": "Cdc42bpg; 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Contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and thus MLC2 phosphorylation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.12.1;2.7.1.153;2.7.1.137;2.7.11.24;2.7.11.25;2.7.11.22;2.7.11.23;2.7.4.6;2.7.1.154;2.7.11.38;2.7.11.17;2.7.11.21;2.7.12.2;2.7.1.40;2.7.11.12;2.7.11.26;2.7.11.34;2.7.10.2;2.7.1.150;2.7.11.13;4.1.1.32;2.7.11.19;2.7.2.3;2.7.11.11;2.7.11.31;3.1.3.16;2.7.11.4;2.3.1.48;3.1.11.-;2.7.13.3;2.7.4.18;3.1.24.-;3.4.19.12;2.7.11.39;2.4.99.18;2.7.11.10", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0031252 cell leading edge", "go_biological_process": "GO:0006468 protein phosphorylation;GO:0031032 actomyosin structure organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3Z837-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3Z854-1", "uniprot_id": "D3Z854_RAT", "mass": 121110.0, "length": 1088, "protein_name": "TELO2-interacting protein 1 homolog", "gene_name": "Tti1", "organism": "Rat", "refseq_name": "TELO2-interacting protein 1 homolog", "refseq_ac": "NP_001128091", "gene_names_uniprotkb": "Tti1", "gene_names_refseq": "RGD1562582; Tti1", "protein_names_uniprotkb": "TELO2-interacting protein 1 homolog", "protein_names_refseq": "TEL2-interacting protein 1 homolog; TELO2-interacting protein 1 homolog; Tel2 interacting protein 1 homolog", "tax_id": 10116, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (rno:499935)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Regulator of the DNA damage response (DDR). 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[provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3Z9W6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3Z9Y1-1", "uniprot_id": "D3Z9Y1_RAT", "mass": 14973.0, "length": 139, "protein_name": "Beta-microseminoprotein", "gene_name": "Msmp", "organism": "Rat", "refseq_name": "prostate-associated microseminoprotein precursor", "refseq_ac": "NP_001258251", "gene_names_uniprotkb": "Msmp", "gene_names_refseq": "Msmp", "protein_names_uniprotkb": "Beta-microseminoprotein", "protein_names_refseq": "prostate-associated microseminoprotein precursor; prostate-associated microseminoprotein; rCG54858-like", "tax_id": 10116, "disease": "", "pathway": " (rno:100365008)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a ligand for C-C chemokine receptor CCR2. Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions. Exhibits a chemotactic activity for monocytes and lymphocytes but not neutrophils., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005125 cytokine activity;GO:0031727 CCR2 chemokine receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm", "go_biological_process": "GO:0006954 inflammatory response;GO:0048247 lymphocyte chemotaxis;GO:0002548 monocyte chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3Z9Y1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3Z9Y6-1", "uniprot_id": "D3Z9Y6_RAT", "mass": 34937.0, "length": 312, "protein_name": "Olfactory receptor", "gene_name": "Or7g29", "organism": "Rat", "refseq_name": "olfactory receptor Olr1147", "refseq_ac": "NP_001000431", "gene_names_uniprotkb": "Or7g29", "gene_names_refseq": "Olr1147; Or7g29", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1147; olfactory receptor Olr1147; olfactory receptor gene Olr1147", "tax_id": 10116, "disease": "", "pathway": " (rno:300408)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3Z9Y6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZA22-1", "uniprot_id": "D3ZA22_RAT", "mass": 70027.0, "length": 642, "protein_name": "E3 ubiquitin-protein ligase TRIM47", "gene_name": "Trim47", "organism": "Rat", "refseq_name": "E3 ubiquitin-protein ligase TRIM47", "refseq_ac": "NP_001103055", "gene_names_uniprotkb": "Trim47", "gene_names_refseq": "Trim47", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase TRIM47; 2.3.2.27; Tripartite motif-containing protein 47", "protein_names_refseq": "E3 ubiquitin-protein ligase TRIM47; tripartite motif protein 47; tripartite motif-containing protein 47", "tax_id": 10116, "disease": "", "pathway": " (rno:690374)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "31178138", "class_list": "", "function": "E3 ubiquitin-protein ligase that mediates the ubiquitination and proteasomal degradation of CYLD., [UniProtKB, UniProtKB]; Trim47 has a role in regulating cerebral ischemia-reperfusion injury through regulating apoptosis and inflammation, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005634 nucleus;GO:0005829 cytosol;GO:0098794 postsynapse", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0150052 regulation of postsynapse assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZA22-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZA48-1", "uniprot_id": "D3ZA48_RAT", "mass": 25653.0, "length": 226, "protein_name": "Fibronectin type III domain containing 9", "gene_name": "Fndc9", "organism": "Rat", "refseq_name": "fibronectin type III domain containing 9", "refseq_ac": "NP_001417254", "gene_names_uniprotkb": "Fndc9", "gene_names_refseq": "Fndc9", "protein_names_uniprotkb": "Fibronectin type III domain containing 9", "protein_names_refseq": "fibronectin type III domain containing 9; fibronectin type III domain-containing protein 9; rCG33426-like", "tax_id": 10116, "disease": "", "pathway": " (rno:100362205)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZA48-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZAQ2-1", "uniprot_id": "D3ZAQ2_RAT", "mass": 53713.0, "length": 495, "protein_name": "Mothers against decapentaplegic homolog", "gene_name": "Smad6", "organism": "Rat", "refseq_name": "mothers against decapentaplegic homolog 6", "refseq_ac": "NP_001102472", "gene_names_uniprotkb": "Smad6", "gene_names_refseq": "Smad6", "protein_names_uniprotkb": "Mothers against decapentaplegic homolog; MAD homolog; Mothers against DPP homolog; SMAD family member", "protein_names_refseq": "MAD homolog 6; mothers against decapentaplegic homolog 6", "tax_id": 10116, "disease": "idiopathic pulmonary fibrosis (Disease Ontology:DOID:0050156); craniosynostosis 7 (Disease Ontology:DOID:0060912); aortic valve disease 2 (Disease Ontology:DOID:0080334); nephritis (Disease Ontology:DOID:10952); pulmonary hypertension (Disease Ontology:DOID:6432); radioulnar synostosis (Disease Ontology:DOID:9827)", "pathway": " (rno:367100); (R-RNO-201451)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "30135141;34449013;35917232", "class_list": "", "function": "MSC secreted extracellular vesicles carrying TGF-beta upregulate Smad 6 expression and promote the regrowth of neurons in spinal cord injured rats., [RefSeq, PubMed]; MiR-134 directly targetted the 3'-UTRs of SMAD6 in the bone marrow mesenchymal stem cells. Publication Status: Online-Only, [RefSeq, PubMed]; MiR-20a-5p regulated SMAD6 to inhibit chondrogenesis of hDPSCs., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0070410 co-SMAD binding;GO:0003682 chromatin binding;GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0071144 heteromeric SMAD protein complex;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016604 nuclear body;GO:0032991 protein-containing complex", "go_biological_process": "GO:0003170 heart valve development;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006955 immune response;GO:0008285 negative regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "D3ZAQ2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZAS0-1", "uniprot_id": "D3ZAS0_RAT", "mass": 20587.0, "length": 187, "protein_name": "Lymphocyte antigen 86", "gene_name": "Ly86", "organism": "Rat", "refseq_name": "lymphocyte antigen 86", "refseq_ac": "NP_001099598", "gene_names_uniprotkb": "Ly86", "gene_names_refseq": "Ly86", "protein_names_uniprotkb": "Lymphocyte antigen 86", "protein_names_refseq": "lymphocyte antigen 86", "tax_id": 10116, "disease": "", "pathway": " (rno:291359); (R-RNO-166016)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0045087 innate immune response;GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZAS0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZAT4-1", "uniprot_id": "D3ZAT4_RAT", "mass": 46841.0, "length": 417, "protein_name": "Serpin family A member 9", "gene_name": "Serpina9", "organism": "Rat", "refseq_name": "serpin A9 precursor", "refseq_ac": "NP_001100224", "gene_names_uniprotkb": "Serpina9", "gene_names_refseq": "Serpina9", "protein_names_uniprotkb": "Serpin family A member 9", "protein_names_refseq": "serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9; serpin A9 precursor; serpin A9; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9; serpin peptidase inhibitor, clade A, member 9", "tax_id": 10116, "disease": "", "pathway": " (rno:299274)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZAT4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZAW4-1", "uniprot_id": "D3ZAW4_RAT", "mass": 40368.0, "length": 355, "protein_name": "(Lyso)-N-acylphosphatidylethanolamine lipase", "gene_name": "Abhd4", "organism": "Rat", "refseq_name": "(Lyso)-N-acylphosphatidylethanolamine lipase", "refseq_ac": "NP_001102336", "gene_names_uniprotkb": "Abhd4", "gene_names_refseq": "Abh4; Abhd4", "protein_names_uniprotkb": "(Lyso)-N-acylphosphatidylethanolamine lipase; Alpha/beta hydrolase domain-containing protein 4; Alpha/beta-hydrolase 4", "protein_names_refseq": "(Lyso)-N-acylphosphatidylethanolamine lipase; abhydrolase domain-containing protein 4", "tax_id": 10116, "disease": "Chanarin-Dorfman syndrome (Disease Ontology:DOID:0050729); obesity (Disease Ontology:DOID:9970)", "pathway": " (rno:364380); (R-RNO-1482839)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "16818490;29393594", "class_list": "", "function": "Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine., [UniProtKB, UniProtKB, UniProtKB]; Lysophospholipase/phospholipase B (EC 3.1.1.5) specific for N-acyl phosphatidylethanolamine (NAPE) suggesting a role in the biosynthesis of N-acyl ethanolamines including the endocannabinoid anandamide., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.1.4", "go_molecular_function": "GO:0004622 phosphatidylcholine lysophospholipase activity;GO:0042171 lysophosphatidic acid acyltransferase activity", "go_cellular_component": "GO:0005811 lipid droplet", "go_biological_process": "GO:0070291 N-acylethanolamine metabolic process;GO:0016042 lipid catabolic process;GO:0070292 N-acylphosphatidylethanolamine metabolic process;GO:0006654 phosphatidic acid biosynthetic process;GO:0055088 lipid homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZAW4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZAY4-1", "uniprot_id": "D3ZAY4_RAT", "mass": 19439.0, "length": 186, "protein_name": "Keratin associated protein 9-7", "gene_name": "Krtap9-7", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Krtap9-7; LOC680396", "gene_names_refseq": "", "protein_names_uniprotkb": "Keratin associated protein 9-7", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0045095 keratin filament", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZAY4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZAZ0-1", "uniprot_id": "D3ZAZ0_RAT", "mass": 41539.0, "length": 366, "protein_name": "Eukaryotic translation initiation factor 3 subunit M", "gene_name": "Eif3m", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Eif3m; EIF3M", "gene_names_refseq": "", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 3 subunit M; eIF3m", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-156827); (R-RNO-72649); (R-RNO-72689); (R-RNO-72695); (R-RNO-72702)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression., [UniProtKB, HAMAP, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003743 translation initiation factor activity;GO:0031369 translation initiation factor binding", "go_cellular_component": "GO:0016282 eukaryotic 43S preinitiation complex;GO:0033290 eukaryotic 48S preinitiation complex;GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m;GO:0005852 eukaryotic translation initiation factor 3 complex", "go_biological_process": "GO:0002183 cytoplasmic translational initiation;GO:0006412 translation;GO:0001732 formation of cytoplasmic translation initiation complex", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZAZ0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZB48-1", "uniprot_id": "D3ZB48_RAT", "mass": 84372.0, "length": 728, "protein_name": "Hook microtubule-tethering protein 1", "gene_name": "Hook1", "organism": "Rat", "refseq_name": "protein Hook homolog 1", "refseq_ac": "NP_001101416", "gene_names_uniprotkb": "Hook1", "gene_names_refseq": "Hook1", "protein_names_uniprotkb": "Hook microtubule-tethering protein 1", "protein_names_refseq": "hook homolog 1; protein Hook homolog 1", "tax_id": 10116, "disease": "Emery-Dreifuss muscular dystrophy (Disease Ontology:DOID:11726)", "pathway": " (rno:313370)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "22673903;30373907", "class_list": "", "function": "It has been found that the dynein effector Hook1 mediates transport of TrkB-BDNF-signaling endosomes in primary hippocampal neurons., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0008017 microtubule binding;GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity;GO:0051959 dynein light intermediate chain binding", "go_cellular_component": "GO:0030897 HOPS complex;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005874 microtubule;GO:0015630 microtubule cytoskeleton", "go_biological_process": "GO:0007286 spermatid development;GO:0007032 endosome organization;GO:0007040 lysosome organization;GO:0008333 endosome to lysosome transport;GO:0045022 early endosome to late endosome transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZB48-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZB91-1", "uniprot_id": "D3ZB91_RAT", "mass": 39680.0, "length": 362, "protein_name": "Zinc phosphodiesterase ELAC protein 1", "gene_name": "Elac1", "organism": "Rat", "refseq_name": "zinc phosphodiesterase ELAC protein 1", "refseq_ac": "NP_001100876", "gene_names_uniprotkb": "Elac1", "gene_names_refseq": "Elac1", "protein_names_uniprotkb": "Zinc phosphodiesterase ELAC protein 1; 3.1.26.11; ElaC homolog protein 1; Ribonuclease Z 1; tRNA 3 endonuclease 1; tRNase Z 1", "protein_names_refseq": "elaC homolog 1; zinc phosphodiesterase ELAC protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:307604)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Specifically involved in tRNA repair: acts downstream of the ribosome-associated quality control (RQC) pathway by removing a 2',3'-cyclic phosphate from tRNAs following cleavage by ANKZF1. tRNAs are then processed by TRNT1., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0042781 3'-tRNA processing endoribonuclease activity;GO:0004549 tRNA-specific ribonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0072344 rescue of stalled ribosome;GO:0042780 tRNA 3'-end processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZB91-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZBD2-1", "uniprot_id": "D3ZBD2_RAT", "mass": 13851.0, "length": 130, "protein_name": "Keratin associated protein 2-4", "gene_name": "Krtap2-4l1", "organism": "Rat", "refseq_name": "keratin-associated protein 2-1", "refseq_ac": "XP_001055917", "gene_names_uniprotkb": "Krtap2-4l1; Krtap2-1; Krtap2-4l2; Krtap2-4l; Krtap2-4; RGD1561281; RGD1561684", "gene_names_refseq": "Krtap2-1", "protein_names_uniprotkb": "Keratin associated protein 2-4", "protein_names_refseq": "keratin-associated protein 2-1", "tax_id": 10116, "disease": "", "pathway": " (rno:501720); (rno:680136); (rno:680152); (R-RNO-6805567)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0045095 keratin filament", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZBD2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZBK4-1", "uniprot_id": "D3ZBK4_RAT", "mass": 46556.0, "length": 419, "protein_name": "Zinc finger protein Pegasus", "gene_name": "Ikzf5", "organism": "Rat", "refseq_name": "zinc finger protein Pegasus", "refseq_ac": "NP_001425159", "gene_names_uniprotkb": "Ikzf5", "gene_names_refseq": "Ikzf5; Zfpn1a5", "protein_names_uniprotkb": "Zinc finger protein Pegasus; Ikaros family zinc finger protein 5", "protein_names_refseq": "zinc finger protein Pegasus; zinc finger protein, subfamily 1A, 5", "tax_id": 10116, "disease": "thrombocytopenia (Disease Ontology:DOID:1588)", "pathway": " (rno:309031)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcriptional repressor that binds the core 5'GNNTGTNG-3' DNA consensus sequence. Involved in megakaryocyte differentiation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0019904 protein domain specific binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0032991 protein-containing complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZBK4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZBN4-1", "uniprot_id": "D3ZBN4_RAT", "mass": 15806.0, "length": 140, "protein_name": "Ergosterol biosynthesis 28 homolog", "gene_name": "Erg28", "organism": "Rat", "refseq_name": "ergosterol biosynthetic protein 28 homolog", "refseq_ac": "NP_001100219", "gene_names_uniprotkb": "Erg28; RGD1310769", "gene_names_refseq": "Erg28; RGD1310769", "protein_names_uniprotkb": "Ergosterol biosynthesis 28 homolog", "protein_names_refseq": "ergosterol biosynthetic protein 28 homolog; probable ergosterol biosynthetic protein 28", "tax_id": 10116, "disease": "", "pathway": " (rno:299207)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0030133 transport vesicle", "go_biological_process": "GO:0016126 sterol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZBN4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZBX0-1", "uniprot_id": "D3ZBX0_RAT", "mass": 38159.0, "length": 332, "protein_name": "C-type lectin domain family 4 member K", "gene_name": "Cd207", "organism": "Rat", "refseq_name": "C-type lectin domain family 4 member K", "refseq_ac": "NP_001414559", "gene_names_uniprotkb": "Cd207", "gene_names_refseq": "Cd207; 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cell cycle checkpoint protein RAD1", "tax_id": 10116, "disease": "", "pathway": " (rno:294800); (R-RNO-176187); (R-RNO-5685938); (R-RNO-5693607); (R-RNO-6804756); (R-RNO-69473)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "37226090", "class_list": "", "function": "Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds; endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths; and DNA ligase I (LIG1) on long-patch base excision repair substrates. The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase., [UniProtKB, UniProtKB]; Rad1 attenuates DNA double-strand breaks and cell cycle arrest in type II alveolar epithelial cells of rats with bronchopulmonary dysplasia. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005694 chromosome;GO:0030896 checkpoint clamp complex", "go_biological_process": "GO:0051598 meiotic recombination checkpoint signaling;GO:0006281 DNA repair;GO:0071479 cellular response to ionizing radiation;GO:0000077 DNA damage checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZC52-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZC97-1", "uniprot_id": "D3ZC97_RAT", "mass": 25208.0, "length": 237, "protein_name": "Regulator of G protein signaling 9 binding protein", "gene_name": "Rgs9bp", "organism": "Rat", "refseq_name": "regulator of G-protein signaling 9-binding protein", "refseq_ac": "NP_001102612", "gene_names_uniprotkb": "Rgs9bp", "gene_names_refseq": "RGD1561747; 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Fads2l1; RGD1311224", "gene_names_refseq": "Fads2b; Fads2l1; RGD1311224", "protein_names_uniprotkb": "Fatty acid desaturase 2B", "protein_names_refseq": "delta-6 fatty acid desaturase; fatty acid desaturase 2-like 1; fatty acid desaturase 2-like protein FADS2B; fatty acid desaturase 2-like protein FADS2P1; linoleoyl-CoA desaturase (delta-6-desaturase)-like 2; uncharacterized protein LOC295714", "tax_id": 10116, "disease": "alcohol use disorder (Disease Ontology:DOID:1574); lipid metabolism disorder (Disease Ontology:DOID:3146)", "pathway": " (rno:295714)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22024496", "class_list": "", "function": "Liver, but not brain, delta-6-desaturase expression and activity indices are negatively regulated by dietary n-3 fatty acids., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "go_cellular_component": "GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0006636 unsaturated fatty acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZCK6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZCM2-1", "uniprot_id": "D3ZCM2_RAT", "mass": 57674.0, "length": 528, "protein_name": "T-box transcription factor TBX21", "gene_name": "Tbx21", "organism": "Rat", "refseq_name": "T-box transcription factor TBX21", "refseq_ac": "NP_001100513", "gene_names_uniprotkb": "Tbx21", "gene_names_refseq": "Tbx21", "protein_names_uniprotkb": "T-box transcription factor TBX21; T-cell-specific T-box transcription factor T-bet; Transcription factor TBLYM", "protein_names_refseq": "T-bet; T-box 21; T-box transcription factor TBX21", "tax_id": 10116, "disease": "immunodeficiency 88 (Disease Ontology:DOID:0061058); childhood-onset asthma (Disease Ontology:DOID:0080815); aspirin-induced respiratory disease (Disease Ontology:DOID:0080822); asthma, nasal polyps, and aspirin intolerance (Disease Ontology:DOID:0111579); malaria (Disease Ontology:DOID:12365); dilated cardiomyopathy (Disease Ontology:DOID:12930); uveitis (Disease Ontology:DOID:13141); orchitis (Disease Ontology:DOID:2518); asthma (Disease Ontology:DOID:2841); autoimmune thyroiditis (Disease Ontology:DOID:7188); periapical periodontitis (Disease Ontology:DOID:823); allergic asthma (Disease Ontology:DOID:9415)", "pathway": " (rno:303496)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "29564567", "class_list": "", "function": "T-bet knockout could attenuate pressure overloadinduced hypertrophy, fibrosis, and inflammation, providing direct evidence that the Th1 subset contributes to cardiac remodelling and can serve as a therapeutic target for pathological cardiac remodeling. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 12, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000976 transcription cis-regulatory region binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0043025 neuronal cell body;GO:0000785 chromatin", "go_biological_process": "GO:0001708 cell fate specification;GO:0032703 negative regulation of interleukin-2 production;GO:2000320 negative regulation of T-helper 17 cell differentiation;GO:0002296 T-helper 1 cell lineage commitment;GO:0000122 negative regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZCM2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZCP6-1", "uniprot_id": "D3ZCP6_RAT", "mass": 121689.0, "length": 1111, "protein_name": "APC membrane recruitment protein 1", "gene_name": "Amer1", "organism": "Rat", "refseq_name": "APC membrane recruitment protein 1", "refseq_ac": "NP_001102790", "gene_names_uniprotkb": "Amer1", "gene_names_refseq": "Amer1; Fam123b; RGD1560322", "protein_names_uniprotkb": "APC membrane recruitment protein 1", "protein_names_refseq": "APC membrane recruitment 1; APC membrane recruitment protein 1; family with sequence similarity 123, member B; family with sequence similarity 123B; protein FAM123B", "tax_id": 10116, "disease": "osteopathia striata with cranial sclerosis (Disease Ontology:DOID:0060886); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (rno:501584); (R-RNO-195253); (R-RNO-196299); (R-RNO-4641262)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0008013 beta-catenin binding;GO:1904713 beta-catenin destruction complex binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016604 nuclear body", "go_biological_process": "GO:0060612 adipose tissue development;GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0001822 kidney development;GO:0016055 Wnt signaling pathway;GO:0031398 positive regulation of protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZCP6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZCQ6-1", "uniprot_id": "D3ZCQ6_RAT", "mass": 20223.0, "length": 185, "protein_name": "Protein Flattop", "gene_name": "Cfap126", "organism": "Rat", "refseq_name": "protein Flattop isoform 1", "refseq_ac": "NP_001102545", "gene_names_uniprotkb": "Cfap126; RGD1562658", "gene_names_refseq": "Cfap126; RGD1562658", "protein_names_uniprotkb": "Protein Flattop; Cilia- and flagella-associated protein 126", "protein_names_refseq": "UPF0740 protein C1orf192 homolog; protein Flattop isoform 1", "tax_id": 10116, "disease": "", "pathway": " (rno:498278)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme. Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. Regulates basal body docking and cilia formation in multiciliated lung cells. Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005929 cilium;GO:0016324 apical plasma membrane;GO:0036126 sperm flagellum;GO:0036064 ciliary basal body;GO:0005879 axonemal microtubule", "go_biological_process": "GO:0030317 flagellated sperm motility;GO:0044782 cilium organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZCQ6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZCR5-1", "uniprot_id": "D3ZCR5_RAT", "mass": 54759.0, "length": 491, "protein_name": "La ribonucleoprotein 6, translational regulator", "gene_name": "Larp6", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Larp6", "gene_names_refseq": "", "protein_names_uniprotkb": "La ribonucleoprotein 6, translational regulator", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:315731)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:1990825 sequence-specific mRNA binding;GO:0003729 mRNA binding;GO:0017022 myosin binding;GO:0048027 mRNA 5'-UTR binding;GO:0035613 RNA stem-loop binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006396 RNA processing;GO:0032967 positive regulation of collagen biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZCR5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZD46-1", "uniprot_id": "D3ZD46_RAT", "mass": 76913.0, "length": 678, "protein_name": "RNA helicase", "gene_name": "Dhx58", "organism": "Rat", "refseq_name": "ATP-dependent RNA helicase DHX58", "refseq_ac": "NP_001092258", "gene_names_uniprotkb": "Dhx58", "gene_names_refseq": "Dhx58; Lgp2; RGD1310093", "protein_names_uniprotkb": "RNA helicase; 3.6.4.13", "protein_names_refseq": "ATP-dependent RNA helicase DHX58; DEXH (Asp-Glu-X-His) box polypeptide 58; RNA helicase LGP2; probable ATP-dependent RNA helicase DHX58", "tax_id": 10116, "disease": "Fanconi anemia (Disease Ontology:DOID:13636)", "pathway": " (rno:303538)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "17020950;29393594", "class_list": "", "function": "Functional analysis of the human LGP2 ortholog., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.6.2.3;3.6.4.13;3.6.4.12;2.7.11.1;3.6.1.5;3.6.4.10;3.6.4.-;2.3.2.27;5.6.2.4;3.6.5.-;5.6.2.-;3.1.-.-;2.7.7.7;2.7.7.49;3.1.13.1;4.2.99.18;7.6.2.2;7.6.2.3;7.6.2.-;5.6.1.6;7.2.2.-;3.6.1.15;3.6.4.6;3.1.3.1;3.9.1.1;6.1.1.12;3.6.1.-;2.7.4.3;3.1.4.-;3.4.24.-;3.6.-.-;3.4.21.53;5.6.2.5", "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0016887 ATP hydrolysis activity;GO:0003725 double-stranded RNA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0005829 cytosol", "go_biological_process": "GO:0009617 response to bacterium;GO:0009615 response to virus;GO:1900245 positive regulation of MDA-5 signaling pathway;GO:1900246 positive regulation of RIG-I signaling pathway;GO:0032481 positive regulation of type I interferon production", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZD46-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZDH5-1", "uniprot_id": "D3ZDH5_RAT", "mass": 35466.0, "length": 315, "protein_name": "Olfactory receptor", "gene_name": "Or2t6", "organism": "Rat", "refseq_name": "olfactory receptor Olr1607", "refseq_ac": "NP_001000534", "gene_names_uniprotkb": "Or2t6", "gene_names_refseq": "Olr1607; Or2t6; ratchr15-12608540-12609487_ORF", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1607; olfactory receptor Olr1607; olfactory receptor gene Olr1607", "tax_id": 10116, "disease": "", "pathway": " (rno:364275)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZDH5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZDI9-1", "uniprot_id": "D3ZDI9_RAT", "mass": 96748.0, "length": 858, "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "Usp13", "organism": "Rat", "refseq_name": "ubiquitin carboxyl-terminal hydrolase 13", "refseq_ac": "NP_001101135", "gene_names_uniprotkb": "Usp13", "gene_names_refseq": "Usp13", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase; 3.4.19.12", "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase 13; ubiquitin specific protease 13 (isopeptidase T-3); ubiquitin thiolesterase 13", "tax_id": 10116, "disease": "", "pathway": " (rno:310306); (R-RNO-5689880); (R-RNO-8948751)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "36916102", "class_list": "", "function": "Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; USP13 reduces septic mediated cardiomyocyte oxidative stress and inflammation by inducing Nrf2. 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tubulin tyrosine ligase-like family, member 2", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-8955332)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0070740 tubulin-glutamic acid ligase activity;GO:0005524 ATP binding;GO:0015631 tubulin binding", "go_cellular_component": "GO:0036064 ciliary basal body", "go_biological_process": "GO:0000226 microtubule cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZF82-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZF96-1", "uniprot_id": "D3ZF96_RAT", "mass": 13487.0, "length": 127, "protein_name": "Lymphocyte antigen 6 family member D", "gene_name": "Ly6d", "organism": "Rat", "refseq_name": "lymphocyte antigen 6D precursor", "refseq_ac": "NP_001124024", "gene_names_uniprotkb": "Ly6d", "gene_names_refseq": "Ly6d", "protein_names_uniprotkb": "Lymphocyte antigen 6 family member D", "protein_names_refseq": "lymphocyte antigen 6 complex, locus D; lymphocyte antigen 6D precursor; lymphocyte antigen 6D", "tax_id": 10116, "disease": "", "pathway": " (rno:315075); (R-RNO-163125)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0035634 response to stilbenoid;GO:0030098 lymphocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZF96-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZFB8-1", "uniprot_id": "D3ZFB8_RAT", "mass": 19712.0, "length": 167, "protein_name": "Similar to human chromosome 5 open reading frame 52", "gene_name": "C14h5orf52", "organism": "Rat", "refseq_name": "uncharacterized protein C5orf52 homolog", "refseq_ac": "NP_001100703", "gene_names_uniprotkb": "C14h5orf52; RGD1308775", "gene_names_refseq": "C14h5orf52; RGD1308775", "protein_names_uniprotkb": "Similar to human chromosome 5 open reading frame 52", "protein_names_refseq": "uncharacterized protein C5orf52 homolog", "tax_id": 10116, "disease": "", "pathway": " (rno:305476)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZFB8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZFD2-1", "uniprot_id": "D3ZFD2_RAT", "mass": 72922.0, "length": 648, "protein_name": "Polypeptide N-acetylgalactosaminyltransferase", "gene_name": "Galnt2", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Galnt2", "gene_names_refseq": "", "protein_names_uniprotkb": "Polypeptide N-acetylgalactosaminyltransferase; 2.4.1.-; Protein-UDP acetylgalactosaminyltransferase", "protein_names_refseq": "", "tax_id": 10116, "disease": "congenital disorder of glycosylation type IIt (Disease Ontology:DOID:0051049)", "pathway": " (rno:292090); (R-RNO-6811436); (R-RNO-913709)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region. Involved in O-linked glycosylation of APOC-III, ANGPTL3 and PLTP. It participates in the regulation of HDL-C metabolism., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.5.2;2.4.1.-;2.4.1.41;3.6.5.-", "go_molecular_function": "GO:0030145 manganese ion binding;GO:0030246 carbohydrate binding;GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity;GO:0046872 metal ion binding;GO:0016757 glycosyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0048471 perinuclear region of cytoplasm;GO:0005795 Golgi stack;GO:0005576 extracellular region", "go_biological_process": "GO:0006493 protein O-linked glycosylation;GO:0016266 protein O-linked glycosylation via N-acetyl-galactosamine;GO:0051604 protein maturation;GO:0002639 positive regulation of immunoglobulin production", "synthesized_glycan_count": 7434, "hit_score": 0.1, "record_id": "D3ZFD2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZFF4-1", "uniprot_id": "D3ZFF4_RAT", "mass": 44566.0, "length": 376, "protein_name": "Lysocardiolipin acyltransferase 1", "gene_name": "Lclat1", "organism": "Rat", "refseq_name": "lysocardiolipin acyltransferase 1 isoform 1", "refseq_ac": "NP_001418858", "gene_names_uniprotkb": "Lclat1", "gene_names_refseq": "Lclat1; Lycat; RGD1565906", "protein_names_uniprotkb": "Lysocardiolipin acyltransferase 1", "protein_names_refseq": "lysocardiolipin acyltransferase 1 isoform 1", "tax_id": 10116, "disease": "", "pathway": " (R-RNO-1482798); (R-RNO-1483166)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "18364741;18605246", "class_list": "", "function": "Cardiac mitochondrial monolysocardiolipin acyltransferase activity declines during postnatal development in the rat and that in utero exposure to alcohol inhibits cardiac monolysocardiolipin acyltransferase, [RefSeq, PubMed]; Data suggest that increased mitochondrial monolysocardiolipin acyltransferase activity, and elevated cardiolipin resynthesis, may be a protective mechanism against monolysocardiolipin-mediated apoptosis., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016746 acyltransferase activity;GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0012505 endomembrane system", "go_biological_process": "GO:0008654 phospholipid biosynthetic process;GO:0036149 phosphatidylinositol acyl-chain remodeling", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZFF4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZFK9-1", "uniprot_id": "D3ZFK9_RAT", "mass": 48848.0, "length": 459, "protein_name": "Protein amnionless", "gene_name": "Amn", "organism": "Rat", "refseq_name": "protein amnionless precursor", "refseq_ac": "NP_001101531", "gene_names_uniprotkb": "Amn", "gene_names_refseq": "Amn", "protein_names_uniprotkb": "Protein amnionless", "protein_names_refseq": "amnionless homolog; protein amnionless precursor; protein amnionless", "tax_id": 10116, "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); megaloblastic anemia (Disease Ontology:DOID:13382); kidney disease (Disease Ontology:DOID:557)", "pathway": " (rno:314459); (R-RNO-8964011); (R-RNO-9758881)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "15976000;17990981;24122887", "class_list": "", "function": "AMN interacts with the EGF domains of cubilin for membrane attachment and export from the endoplasmic reticulum, while extracellular cubilin does apical sorting of the complex in a carbohydrate-dependent manner, [RefSeq, PubMed]; Three distinct regions of cubilin bind to megalin and its interactions with both megalin and amnionless are essential for its intracellular stability., [RefSeq, PubMed]; We conclude that the megalin/cubilin/amnionless/Dab2 complex/es participate in intestinal processes, mainly during the lactation period and that Dab2 may act as an adaptor in intestinal processes mediated by ApoER2 and VLDLR., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0038024 cargo receptor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane;GO:0043235 receptor complex;GO:0045177 apical part of cell;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0097017 renal protein absorption;GO:0006898 receptor-mediated endocytosis;GO:0009235 cobalamin metabolic process;GO:0008104 intracellular protein localization;GO:0015889 cobalamin transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "D3ZFK9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZFQ4-1", "uniprot_id": "D3ZFQ4_RAT", "mass": 87304.0, "length": 778, "protein_name": "Zinc finger and SCAN domain-containing protein 10", "gene_name": "Zscan10", "organism": "Rat", "refseq_name": "zinc finger and SCAN domain-containing protein 10", "refseq_ac": "NP_001100451", "gene_names_uniprotkb": "Zscan10", "gene_names_refseq": "Zfp206; Znf206; Zscan10", "protein_names_uniprotkb": "Zinc finger and SCAN domain-containing protein 10; Zinc finger protein 206", "protein_names_refseq": "zinc finger and SCAN domain-containing protein 10; zinc finger protein 206", "tax_id": 10116, "disease": "", "pathway": " (rno:302962)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Embryonic stem (ES) cell-specific transcription factor required to maintain ES cell pluripotency. Can both activate and /or repress expression of target genes, depending on the context. Specifically binds the 5'-[GA]CGCNNGCG[CT]-3' DNA consensus sequence. Regulates expression of POU5F1/OCT4, ZSCAN4 and ALYREF/THOC4., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZFQ4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZFQ5-1", "uniprot_id": "D3ZFQ5_RAT", "mass": 88793.0, "length": 788, "protein_name": "Cadherin 9", "gene_name": "Cdh9", "organism": "Rat", "refseq_name": "cadherin-9 precursor", "refseq_ac": "NP_001162101", "gene_names_uniprotkb": "Cdh9", "gene_names_refseq": "Cdh9", "protein_names_uniprotkb": "Cadherin 9", "protein_names_refseq": "cadherin 9, type 2, T1-cadherin; cadherin-9 precursor", "tax_id": 10116, "disease": "prostate cancer (Disease Ontology:DOID:10283); cancer (Disease Ontology:DOID:162)", "pathway": " (rno:29163); (R-RNO-418990)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "22673903;33794525", "class_list": "", "function": "Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types., [UniProtKB, UniProtKB, UniProtKB]; MiR-22-3p Suppresses Vascular Remodeling and Oxidative Stress by Targeting CHD9 during the Development of Hypertension., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0045296 cadherin binding;GO:0008013 beta-catenin binding;GO:0042802 identical protein binding;GO:0098641 cadherin binding involved in cell-cell adhesion", "go_cellular_component": "GO:0005912 adherens junction;GO:0045211 postsynaptic membrane;GO:0016342 catenin complex;GO:0042734 presynaptic membrane;GO:0098978 glutamatergic synapse", "go_biological_process": "GO:0016477 cell migration;GO:0000902 cell morphogenesis;GO:0007416 synapse assembly;GO:0007043 cell-cell junction assembly;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZFQ5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZFQ8-1", "uniprot_id": "D3ZFQ8_RAT", "mass": 35435.0, "length": 326, "protein_name": "Cytochrome c1, heme protein, mitochondrial", "gene_name": "Cyc1", "organism": "Rat", "refseq_name": "cytochrome c-1", "refseq_ac": "NP_001264123", "gene_names_uniprotkb": "Cyc1", "gene_names_refseq": "Cyc1", "protein_names_uniprotkb": "Cytochrome c1, heme protein, mitochondrial; Complex III subunit 4; Complex III subunit IV; Cytochrome b-c1 complex subunit 4; Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit", "protein_names_refseq": "cytochrome c-1", "tax_id": 10116, "disease": "mitochondrial complex III deficiency nuclear type 6 (Disease Ontology:DOID:0080115)", "pathway": " (rno:300047); (R-RNO-611105); (R-RNO-9865881)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "38843836", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0009055 electron transfer activity;GO:0046872 metal ion binding;GO:0020037 heme binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0045275 respiratory chain complex III", "go_biological_process": "GO:0033762 response to glucagon;GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "D3ZFQ8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZFW8-1", "uniprot_id": "D3ZFW8_RAT", "mass": 40757.0, "length": 356, "protein_name": "Chemokine (C-C motif) receptor 1-like 1", "gene_name": "Ccr1l1", "organism": "Rat", "refseq_name": "C-C chemokine receptor 1-like protein 1", "refseq_ac": "NP_001100342", "gene_names_uniprotkb": "Ccr1l1", "gene_names_refseq": "Ccr1l1", "protein_names_uniprotkb": "Chemokine (C-C motif) receptor 1-like 1", "protein_names_refseq": "C-C chemokine receptor 1-like protein 1", "tax_id": 10116, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); Lewy body dementia (Disease Ontology:DOID:12217); allergic contact dermatitis (Disease Ontology:DOID:3042); coronary artery disease (Disease Ontology:DOID:3393); liver cirrhosis (Disease Ontology:DOID:5082); rheumatoid arthritis (Disease Ontology:DOID:7148); cerebral amyloid angiopathy (Disease Ontology:DOID:9246)", "pathway": " (rno:301088); (R-RNO-418594)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016493 C-C chemokine receptor activity;GO:0071791 chemokine (C-C motif) ligand 5 binding;GO:0035717 chemokine (C-C motif) ligand 7 binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0006954 inflammatory response;GO:0006955 immune response;GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0019722 calcium-mediated signaling;GO:0090026 positive regulation of monocyte chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZFW8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZFX1-1", "uniprot_id": "D3ZFX1_RAT", "mass": 33428.0, "length": 296, "protein_name": "Transmembrane protein 164", "gene_name": "Tmem164", "organism": "Rat", "refseq_name": "transmembrane protein 164 isoform 2", "refseq_ac": "NP_001102484", "gene_names_uniprotkb": "Tmem164", "gene_names_refseq": "RGD1563286; Tmem164", "protein_names_uniprotkb": "Transmembrane protein 164", "protein_names_refseq": "transmembrane protein 164 isoform 2", "tax_id": 10116, "disease": "", "pathway": " (rno:367763)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0160020 positive regulation of ferroptosis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZFX1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZG11-1", "uniprot_id": "D3ZG11_RAT", "mass": 75460.0, "length": 688, "protein_name": "Solute carrier family 5 member 9", "gene_name": "Slc5a9", "organism": "Rat", "refseq_name": "sodium/glucose cotransporter 4", "refseq_ac": "NP_001382057", "gene_names_uniprotkb": "Slc5a9", "gene_names_refseq": "Slc5a9", "protein_names_uniprotkb": "Solute carrier family 5 member 9", "protein_names_refseq": "sodium/glucose cotransporter 4; solute carrier family 5 (sodium/glucose cotransporter), member 9; solute carrier family 5 (sodium/sugar cotransporter), member 9", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZG11-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZG28-1", "uniprot_id": "D3ZG28_RAT", "mass": 64704.0, "length": 610, "protein_name": "Solute carrier family 23, member 3", "gene_name": "Slc23a3", "organism": "Rat", "refseq_name": "solute carrier family 23 member 3", "refseq_ac": "NP_001102476", "gene_names_uniprotkb": "Slc23a3", "gene_names_refseq": "Slc23a3", "protein_names_uniprotkb": "Solute carrier family 23, member 3", "protein_names_refseq": "solute carrier family 23 (nucleobase transporters), member 3; solute carrier family 23 member 3", "tax_id": 10116, "disease": "", "pathway": " (rno:367298)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0035344 hypoxanthine transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZG28-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZG90-1", "uniprot_id": "D3ZG90_RAT", "mass": 39278.0, "length": 342, "protein_name": "Alpha-1,4-N-acetylglucosaminyltransferase", "gene_name": "A4gnt", "organism": "Rat", "refseq_name": "alpha-1,4-N-acetylglucosaminyltransferase", "refseq_ac": "NP_001413844", "gene_names_uniprotkb": "A4gnt", "gene_names_refseq": "A4gnt", "protein_names_uniprotkb": "Alpha-1,4-N-acetylglucosaminyltransferase", "protein_names_refseq": "alpha-1,4-N-acetylglucosaminyltransferase", "tax_id": 10116, "disease": "pancreatic cancer (Disease Ontology:DOID:1793)", "pathway": " (rno:685758); 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a disintegrin and metalloproteinase domain 30; disintegrin and metalloproteinase domain-containing protein 30 precursor; disintegrin and metalloproteinase domain-containing protein 30", "tax_id": 10116, "disease": "", "pathway": " (rno:690547)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009897 external side of plasma membrane;GO:1990913 sperm head plasma membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0008584 male gonad development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZIP6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZJA9-1", "uniprot_id": "D3ZJA9_RAT", "mass": 72458.0, "length": 667, "protein_name": "long-chain-fatty-acid--CoA ligase", "gene_name": "Slc27a3", "organism": "Rat", "refseq_name": "long-chain fatty acid transport protein 3 precursor", "refseq_ac": "NP_001099909", "gene_names_uniprotkb": "Slc27a3", "gene_names_refseq": "Slc27a3", "protein_names_uniprotkb": "long-chain-fatty-acid--CoA ligase; 6.2.1.3; Long-chain-fatty-acid--CoA ligase", "protein_names_refseq": "long-chain fatty acid transport protein 3 precursor; long-chain fatty acid transport protein 3; solute carrier family 27 (fatty acid transporter), member 3", "tax_id": 10116, "disease": "", "pathway": " (rno:295219)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "6.2.1.3;6.2.1.15;6.2.1.76;6.2.1.7;6.2.1.-;6.2.1.24", "go_molecular_function": "GO:0000166 nucleotide binding;GO:0004467 long-chain fatty acid-CoA ligase activity;GO:0031957 very long-chain fatty acid-CoA ligase activity;GO:0004321 fatty-acyl-CoA synthase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0001676 long-chain fatty acid metabolic process;GO:0015908 fatty acid transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZJA9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZJB2-1", "uniprot_id": "D3ZJB2_RAT", "mass": 36295.0, "length": 329, "protein_name": "Glycosylated integral membrane protein 1", "gene_name": "Ginm1", "organism": "Rat", "refseq_name": "glycoprotein integral membrane protein 1 precursor", "refseq_ac": "NP_001387767", "gene_names_uniprotkb": "Ginm1", "gene_names_refseq": "Ginm1; 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Arih2; TRIAD1", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase ARIH2; 2.3.2.31; Triad1 protein", "protein_names_refseq": "E3 ubiquitin-protein ligase ARIH2; ariadne homolog 2", "tax_id": 10116, "disease": "", "pathway": " (rno:316005); (R-RNO-983168)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "30320922;30409224;34641746;36055408", "class_list": "", "function": "E3 ubiquitin ligase Triad1 promotes neuronal apoptosis by regulating the p53-caspase3 pathway after spinal cord injury., [RefSeq, PubMed]; Our data delineate a novel interaction between Triad1 and EHD1 that may contribute to the regulation of neurite outgrowth for neurons after the spinal cord injury., [RefSeq, PubMed]; The expression of TRIAD1 and DISC1 change after traumatic brain injury and that their interaction may affect the proliferation and differentiation of neural stem cells. Publication Status: Online-Only, [RefSeq, PubMed]; Ubiquitin ligase Triad1 promotes neurite outgrowth by inhibiting MDM2-mediated ubiquitination of the neuroprotective factor pleiotrophin., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.2.26;2.3.2.32;2.3.2.31;2.3.2.23;2.3.2.27;2.3.2.34;2.3.2.24;2.3.2.-;2.3.2.25", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0031624 ubiquitin conjugating enzyme binding;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0000151 ubiquitin ligase complex;GO:0031466 Cul5-RING ubiquitin ligase complex", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0016567 protein ubiquitination;GO:0000209 protein polyubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0070936 protein K48-linked ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "D3ZJB8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZJF7-1", "uniprot_id": "D3ZJF7_RAT", "mass": 59887.0, "length": 536, "protein_name": "Telomeric repeat-binding factor", "gene_name": "Terf2", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Terf2", "gene_names_refseq": "", "protein_names_uniprotkb": "Telomeric repeat-binding factor", "protein_names_refseq": "", "tax_id": 10116, "disease": "xeroderma pigmentosum (Disease Ontology:DOID:0050427)", "pathway": " (R-RNO-110330); (R-RNO-110331); (R-RNO-171319); (R-RNO-174411); (R-RNO-174414); (R-RNO-174417); (R-RNO-174430); (R-RNO-174437); (R-RNO-2559586)", "pathway_count": 9, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Binds the telomeric double-stranded 5'-TTAGGG-3' repeat., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0098505 G-rich strand telomeric DNA binding;GO:0019899 enzyme binding;GO:0042803 protein homodimerization activity;GO:0042162 telomeric DNA binding;GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0030424 axon;GO:0016604 nuclear body;GO:0000783 nuclear telomere cap complex", "go_biological_process": "GO:0032205 negative regulation of telomere maintenance;GO:0032204 regulation of telomere maintenance;GO:1904430 negative regulation of t-circle formation;GO:0001701 in utero embryonic development;GO:0000723 telomere maintenance", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZJF7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZJG8-1", "uniprot_id": "D3ZJG8_RAT", "mass": 137752.0, "length": 1262, "protein_name": "Zinc finger protein 592", "gene_name": "Zfp592", "organism": "Rat", "refseq_name": "zinc finger protein 592", "refseq_ac": "NP_001099742", "gene_names_uniprotkb": "Zfp592", "gene_names_refseq": "Zfp592; Znf592", "protein_names_uniprotkb": "Zinc finger protein 592", "protein_names_refseq": "zinc finger protein 592", "tax_id": 10116, "disease": "", "pathway": " (rno:293038); (R-RNO-9940951)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZJG8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZJJ6-1", "uniprot_id": "D3ZJJ6_RAT", "mass": 14141.0, "length": 124, "protein_name": "60S ribosomal protein L36", "gene_name": "Rpl36l6", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Rpl36l6; LOC100359616", "gene_names_refseq": "", "protein_names_uniprotkb": "60S ribosomal protein L36", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:100359616)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005840 ribosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZJJ6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZJQ8-1", "uniprot_id": "D3ZJQ8_RAT", "mass": 28897.0, "length": 253, "protein_name": "Ring finger protein 151", "gene_name": "Rnf151", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Rnf151", "gene_names_refseq": "", "protein_names_uniprotkb": "Ring finger protein 151", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:302977)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZJQ8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZJT5-1", "uniprot_id": "D3ZJT5_RAT", "mass": 35222.0, "length": 312, "protein_name": "Olfactory receptor", "gene_name": "Or52j3b", "organism": "Rat", "refseq_name": "olfactory receptor Olr81", "refseq_ac": "NP_001001271", "gene_names_uniprotkb": "Or52j3b", "gene_names_refseq": "Olr81; Or52j3b", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 81; olfactory receptor Olr81; olfactory receptor gene Olr81", "tax_id": 10116, "disease": "", "pathway": " (rno:293224)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3ZL01", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZJT5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZJX5-1", "uniprot_id": "D3ZJX5_RAT", "mass": 40027.0, "length": 354, "protein_name": "Mitochondrial import inner membrane translocase subunit TIM50", "gene_name": "Timm50", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Timm50; LOC687295", "gene_names_refseq": "", "protein_names_uniprotkb": "Mitochondrial import inner membrane translocase subunit TIM50", "protein_names_refseq": "", "tax_id": 10116, "disease": "3-methylglutaconic aciduria type 9 (Disease Ontology:DOID:0070002); cancer (Disease Ontology:DOID:162)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0043021 ribonucleoprotein complex binding;GO:0004722 protein serine/threonine phosphatase activity;GO:0004721 phosphoprotein phosphatase activity;GO:0005134 interleukin-2 receptor binding;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0001836 release of cytochrome c from mitochondria;GO:0006470 protein dephosphorylation;GO:0030150 protein import into mitochondrial matrix;GO:0007006 mitochondrial membrane organization;GO:0015031 protein transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZJX5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZJY1-1", "uniprot_id": "D3ZJY1_RAT", "mass": 30237.0, "length": 257, "protein_name": "Large ribosomal subunit protein bL28m", "gene_name": "Mrpl28", "organism": "Rat", "refseq_name": "large ribosomal subunit protein bL28m", "refseq_ac": "NP_001385745", "gene_names_uniprotkb": "Mrpl28", "gene_names_refseq": "Mrpl28", "protein_names_uniprotkb": "Large ribosomal subunit protein bL28m; 39S ribosomal protein L28, mitochondrial", "protein_names_refseq": "39S ribosomal protein L28, mitochondrial; large ribosomal subunit protein bL28m", "tax_id": 10116, "disease": "", "pathway": " (rno:497876); (R-RNO-5389840); (R-RNO-5419276); (R-RNO-9937383)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0005739 mitochondrion;GO:0005761 mitochondrial ribosome", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZJY1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZK72-1", "uniprot_id": "D3ZK72_RAT", "mass": 9735.0, "length": 95, "protein_name": "Keratin associated protein 16-5", "gene_name": "Krtap16-5", "organism": "Rat", "refseq_name": "keratin-associated protein 19-1", "refseq_ac": "NP_001102894", "gene_names_uniprotkb": "Krtap16-5", "gene_names_refseq": "Krtap16-5", "protein_names_uniprotkb": "Keratin associated protein 16-5", "protein_names_refseq": "keratin-associated protein 19-1", "tax_id": 10116, "disease": "", "pathway": " (rno:680703); (R-RNO-6805567)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0005882 intermediate filament", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZK72-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZKJ8-1", "uniprot_id": "D3ZKJ8_RAT", "mass": 67147.0, "length": 605, "protein_name": "Endonuclease 8-like 3", "gene_name": "Neil3", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Neil3", "gene_names_refseq": "", "protein_names_uniprotkb": "Endonuclease 8-like 3; 4.2.99.18; DNA glycosylase FPG2; DNA glycosylase/AP lyase Neil3; Endonuclease VIII-like 3; Nei-like protein 3", "protein_names_refseq": "", "tax_id": 10116, "disease": "hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (R-RNO-110330); (R-RNO-110331)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA). Mediates interstrand cross-link repair in response to replication stress: acts by mediating DNA glycosylase activity, cleaving one of the two N-glycosyl bonds comprising the interstrand cross-link, which avoids the formation of a double-strand break but generates an abasic site that is bypassed by translesion synthesis polymerases. In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA; also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5-OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity. In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.14.11.51;4.2.99.18;1.14.11.33;3.2.2.-;5.6.2.4;2.7.7.7;4.2.99.-", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003684 damaged DNA binding;GO:0019104 DNA N-glycosylase activity;GO:0003690 double-stranded DNA binding;GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006284 base-excision repair;GO:0000012 single strand break repair", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZKJ8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZKN4-1", "uniprot_id": "D3ZKN4_RAT", "mass": 80970.0, "length": 721, "protein_name": "WASP homolog associated with actin, golgi membranes and microtubules", "gene_name": "Whamm", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Whamm", "gene_names_refseq": "", "protein_names_uniprotkb": "WASP homolog associated with actin, golgi membranes and microtubules", "protein_names_refseq": "", "tax_id": 10116, "disease": "Fanconi syndrome (Disease Ontology:DOID:1062)", "pathway": " (rno:293057)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "22673903;29393594", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0008017 microtubule binding;GO:0031267 small GTPase binding;GO:0071933 Arp2/3 complex binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0030659 cytoplasmic vesicle membrane", "go_biological_process": "GO:0007015 actin filament organization;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0030032 lamellipodium assembly;GO:0048041 focal adhesion assembly;GO:0034314 Arp2/3 complex-mediated actin nucleation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZKN4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZKP1-1", "uniprot_id": "D3ZKP1_RAT", "mass": 55578.0, "length": 508, "protein_name": "Ankyrin repeat domain 34B", "gene_name": "Ankrd34b", "organism": "Rat", "refseq_name": "ankyrin repeat domain-containing protein 34B", "refseq_ac": "NP_001102644", "gene_names_uniprotkb": "Ankrd34b", "gene_names_refseq": "Ankrd34b; Dp58", "protein_names_uniprotkb": "Ankyrin repeat domain 34B", "protein_names_refseq": "ankyrin repeat domain-containing protein 34B; cytosolic phosphoprotein DP58", "tax_id": 10116, "disease": "", "pathway": " (rno:499506)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZKP1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZL57-1", "uniprot_id": "D3ZL57_RAT", "mass": 93276.0, "length": 816, "protein_name": "USP6 N-terminal-like protein", "gene_name": "Usp6nl", "organism": "Rat", "refseq_name": "USP6 N-terminal-like protein", "refseq_ac": "NP_001099590", "gene_names_uniprotkb": "Usp6nl", "gene_names_refseq": "Usp6nl", "protein_names_uniprotkb": "USP6 N-terminal-like protein", "protein_names_refseq": "USP6 N-terminal-like protein", "tax_id": 10116, "disease": "", "pathway": " (rno:291309); (R-RNO-6811440)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "Acts as a GTPase-activating protein for RAB43, RAB5A and RAB30. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0043547 positive regulation of GTPase activity;GO:0007030 Golgi organization;GO:0048227 plasma membrane to endosome transport;GO:1903358 regulation of Golgi organization;GO:0035526 retrograde transport, plasma membrane to Golgi", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZL57-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZLA3-1", "uniprot_id": "D3ZLA3_RAT", "mass": 70126.0, "length": 628, "protein_name": "Copine-3", "gene_name": "Cpne3", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Cpne3", "gene_names_refseq": "", "protein_names_uniprotkb": "Copine-3; Copine III", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:313087); (R-RNO-1483206); (R-RNO-6798695)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Calcium-dependent phospholipid-binding protein that plays a role in ERBB2-mediated tumor cell migration in response to growth factor heregulin stimulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0048306 calcium-dependent protein binding;GO:0030971 receptor tyrosine kinase binding;GO:0005544 calcium-dependent phospholipid binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0030335 positive regulation of cell migration;GO:0071277 cellular response to calcium ion;GO:0071363 cellular response to growth factor stimulus;GO:0038128 ERBB2 signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZLA3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZLB5-1", "uniprot_id": "D3ZLB5_RAT", "mass": 31651.0, "length": 283, "protein_name": "Phospholipase A2", "gene_name": "Pla2g2f", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Pla2g2f", "gene_names_refseq": "", "protein_names_uniprotkb": "Phospholipase A2; 3.1.1.4", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": " (rno:690388); (R-RNO-1482788); (R-RNO-1482801); (R-RNO-1482839); (R-RNO-1482922); (R-RNO-1482925); (R-RNO-1483166)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.1.4;3.1.1.32;2.3.1.-;2.3.1.51;3.1.1.3;3.1.1.-;3.1.1.5;1.11.1.27;2.3.1.23;3.1.2.2;3.1.1.23;3.1.-.-", "go_molecular_function": "GO:0005543 phospholipid binding;GO:0005509 calcium ion binding;GO:0004623 phospholipase A2 activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0036148 phosphatidylglycerol acyl-chain remodeling;GO:0016042 lipid catabolic process;GO:0042130 negative regulation of T cell proliferation;GO:0050482 arachidonate secretion;GO:0036152 phosphatidylethanolamine acyl-chain remodeling", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZLB5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZLB7-1", "uniprot_id": "FOSB_RAT", "mass": 35979.0, "length": 338, "protein_name": "Protein FosB", "gene_name": "Fosb", "organism": "Rat", "refseq_name": "protein FosB", "refseq_ac": "NP_001243438", "gene_names_uniprotkb": "Fosb", "gene_names_refseq": "Fosb; fra-2", "protein_names_uniprotkb": "Protein FosB; Transcription factor AP-1 subunit FosB", "protein_names_refseq": "FBJ osteosarcoma oncogene B; protein FosB; transcription factor AP-1 subunit FosB", "tax_id": 10116, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); nicotine dependence (Disease Ontology:DOID:0050742); tongue squamous cell carcinoma (Disease Ontology:DOID:0050865); withdrawal disorder (Disease Ontology:DOID:0060001); opioid abuse (Disease Ontology:DOID:11206); alcohol use disorder (Disease Ontology:DOID:1574); depressive disorder (Disease Ontology:DOID:1596); morphine dependence (Disease Ontology:DOID:2560); amphetamine abuse (Disease Ontology:DOID:670); cocaine abuse (Disease Ontology:DOID:809); substance dependence (Disease Ontology:DOID:9973); cocaine dependence (Disease Ontology:DOID:9975); heroin dependence (Disease Ontology:DOID:9976)", "pathway": " (rno:100360880)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "16687504;26446228;33677486;34699790;37642495", "class_list": "", "function": "CircRNA_01477 influences axonal growth via regulating miR-3075/FosB/Stat3 axis., [RefSeq, PubMed]; Gestational intermittent hypoxia increases FosB-immunoreactive perikaryas in the paraventricular nucleus of the hypothalamus of adult male (but not female) rats., [RefSeq, PubMed]; Heterodimerizes with proteins of the JUN family to form an AP-1 transcription factor complex, thereby enhancing their DNA binding activity to an AP-1 consensus sequence 5'-TGA[GC]TCA-3' and enhancing their transcriptional activity (By similarity). Exhibits transactivation activity in vitro (By similarity). As part of the AP-1 complex, facilitates enhancer selection together with cell-type-specific transcription factors by collaboratively binding to nucleosomal enhancers and recruiting the SWI/SNF (BAF) chromatin remodeling complex to establish accessible chromatin (By similarity). Together with JUN, plays a role in activation-induced cell death of T cells by binding to the AP-1 promoter site of FASLG/CD95L, and inducing its transcription in response to activation of the TCR/CD3 signaling pathway (By similarity). Involved in the display of nurturing behavior towards newborns (By similarity). May play a role in neurogenesis in the hippocampus and in learning and memory-related tasks by regulating the expression of various genes involved in neurogenesis, depression and epilepsy (By similarity). Implicated in behavioral responses related to morphine reward and spatial memory (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; NF-kappaB and FosB mediate inflammation and oxidative stress in the blast lung injury of rats exposed to shock waves., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 13, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0003690 double-stranded DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0035094 response to nicotine;GO:0045471 response to ethanol;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0001975 response to amphetamine", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "D3ZLB7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZLL7-1", "uniprot_id": "D3ZLL7_RAT", "mass": 135928.0, "length": 1221, "protein_name": "ADAM metallopeptidase with thrombospondin type 1 motif, 16", "gene_name": "Adamts16", "organism": "Rat", "refseq_name": "A disintegrin and metalloproteinase with thrombospondin motifs 16 precursor", "refseq_ac": "NP_001358944", "gene_names_uniprotkb": "Adamts16", "gene_names_refseq": "Adamts16", "protein_names_uniprotkb": "ADAM metallopeptidase with thrombospondin type 1 motif, 16", "protein_names_refseq": "A disintegrin and metalloproteinase with thrombospondin motifs 16 precursor; A disintegrin and metalloproteinase with thrombospondin motifs 16; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 16", "tax_id": 10116, "disease": "hypertension (Disease Ontology:DOID:10763); cryptorchidism (Disease Ontology:DOID:11383); male infertility (Disease Ontology:DOID:12336)", "pathway": " (rno:306664); (R-RNO-5173214)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "19423552;23185005;24983376;32037220", "class_list": "", "function": "Genetic variation of Adamts16 is linked to inherited hypertension in a rat model. Erratum:[Hum Mol Genet. 2011 Nov 1;20(21):4297. Dhindaw, Seema [added]], [RefSeq, PubMed]; Interplay between collagenase and undescended testes in Adamts16 knockout rats., [RefSeq, PubMed]; Physiological observations functionally link Adamts16 to blood pressure regulation and suggest the vasculature as the potential site of action of Adamts16 to lower blood pressure, [RefSeq, PubMed]; These observations, taken together with our previous report of renal abnormalities observed with the same Adamts16mutant rats, suggest an important mechanistic link between Adamts16 and the functioning of the male genitourinary system. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0031012 extracellular matrix", "go_biological_process": "GO:0006508 proteolysis;GO:0030198 extracellular matrix organization;GO:0003073 regulation of systemic arterial blood pressure;GO:0001658 branching involved in ureteric bud morphogenesis;GO:1902017 regulation of cilium assembly", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "D3ZLL7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZLR2-1", "uniprot_id": "D3ZLR2_RAT", "mass": 34984.0, "length": 312, "protein_name": "Olfactory receptor", "gene_name": "Or51i2", "organism": "Rat", "refseq_name": "olfactory receptor Olr143", "refseq_ac": "NP_001000163", "gene_names_uniprotkb": "Or51i2", "gene_names_refseq": "Olr143; Or51i2", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 143; olfactory receptor Olr143; olfactory receptor gene Olr143", "tax_id": 10116, "disease": "", "pathway": " (rno:293281)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0071396 cellular response to lipid", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZLR2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZLR9-1", "uniprot_id": "D3ZLR9_RAT", "mass": 32497.0, "length": 292, "protein_name": "2P domain potassium channel Talk-1", "gene_name": "Kcnk16", "organism": "Rat", "refseq_name": "potassium channel subfamily K member 16", "refseq_ac": "NP_001102990", "gene_names_uniprotkb": "Kcnk16", "gene_names_refseq": "Kcnk16", "protein_names_uniprotkb": "2P domain potassium channel Talk-1; TWIK-related alkaline pH-activated K(+) channel 1", "protein_names_refseq": "potassium channel subfamily K member 16; potassium channel, subfamily K, member 16; potassium channel, two pore domain subfamily K, member 16", "tax_id": 10116, "disease": "heart conduction disease (Disease Ontology:DOID:10273)", "pathway": " (rno:688996); (R-RNO-1299361); (R-RNO-5576886)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.8.-.-", "go_molecular_function": "GO:0015271 outward rectifier potassium channel activity;GO:0022841 potassium ion leak channel activity;GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0086011 membrane repolarization during action potential;GO:0098900 regulation of action potential;GO:0006813 potassium ion transport;GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0051279 regulation of release of sequestered calcium ion into cytosol", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZLR9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZLU2-1", "uniprot_id": "D3ZLU2_RAT", "mass": 35024.0, "length": 315, "protein_name": "Olfactory receptor family 8 subfamily B member 57", "gene_name": "Or8b57", "organism": "Rat", "refseq_name": "olfactory receptor Olr1338", "refseq_ac": "NP_001000789", "gene_names_uniprotkb": "Or8b57", "gene_names_refseq": "Olr1338; Or8b57", "protein_names_uniprotkb": "Olfactory receptor family 8 subfamily B member 57", "protein_names_refseq": "olfactory receptor 1338; olfactory receptor Olr1338; olfactory receptor gene Olr1338", "tax_id": 10116, "disease": "", "pathway": " (rno:405073)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "M0RA67", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZLU2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZLU7-1", "uniprot_id": "D3ZLU7_RAT", "mass": 23053.0, "length": 199, "protein_name": "Similar to human chromosome 2 open reading frame 74", "gene_name": "C14h2orf74", "organism": "Rat", "refseq_name": "uncharacterized protein C2orf74 homolog", "refseq_ac": "NP_001406284", "gene_names_uniprotkb": "C14h2orf74; LOC690352", "gene_names_refseq": "C14h2orf74", "protein_names_uniprotkb": "Similar to human chromosome 2 open reading frame 74", "protein_names_refseq": "uncharacterized protein C2orf74 homolog", "tax_id": 10116, "disease": "visceral heterotaxy (Disease Ontology:DOID:0050545)", "pathway": " (rno:690352)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZLU7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZM21-1", "uniprot_id": "D3ZM21_RAT", "mass": 28987.0, "length": 262, "protein_name": "Catechol-O-methyltransferase domain containing 1", "gene_name": "Comtd1", "organism": "Rat", "refseq_name": "catechol O-methyltransferase domain-containing protein 1", "refseq_ac": "NP_001100719", "gene_names_uniprotkb": "Comtd1", "gene_names_refseq": "Comtd1", "protein_names_uniprotkb": "Catechol-O-methyltransferase domain containing 1", "protein_names_refseq": "catechol O-methyltransferase domain-containing protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:305685)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008757 S-adenosylmethionine-dependent methyltransferase activity;GO:0008171 O-methyltransferase activity", "go_cellular_component": "", "go_biological_process": "GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZM21-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZM22-1", "uniprot_id": "D3ZM22_RAT", "mass": 55034.0, "length": 514, "protein_name": "Solute carrier family 41 member", "gene_name": "Slc41a1", "organism": "Rat", "refseq_name": "solute carrier family 41 member 1", "refseq_ac": "NP_001102325", "gene_names_uniprotkb": "Slc41a1", "gene_names_refseq": "Slc41a1", "protein_names_uniprotkb": "Solute carrier family 41 member", "protein_names_refseq": "solute carrier family 41 (magnesium transporter), member 1; solute carrier family 41 member 1", "tax_id": 10116, "disease": "nephronophthisis (Disease Ontology:DOID:12712); Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (rno:363985); (R-RNO-425410)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "22673903;25263961;30172737", "class_list": "", "function": "6-OHDA lesion induction alters the expression of the endogenous magnesium transporter SLC41A1 in a rat model of parkinsonian disease, and that the changes are responsive to a certain concentration of MgSO4. The administration of MgSO4 before the degenerative process commenced was effective in ameliorating the motor behavior and to some extent preventing DAnergic neurons from degeneration., [RefSeq, PubMed]; Acts as a magnesium transporter., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; SLC41A1 knockdown inhibits angiotensin II-induced cardiac fibrosis by preventing Mg(2+) efflux and Ca(2+) signaling in cardiac fibroblasts., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008324 monoatomic cation transmembrane transporter activity;GO:0022857 transmembrane transporter activity;GO:0061768 magnesium:sodium antiporter activity;GO:0015095 magnesium ion transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0016323 basolateral plasma membrane;GO:0032991 protein-containing complex", "go_biological_process": "GO:1903830 magnesium ion transmembrane transport;GO:0071286 cellular response to magnesium ion;GO:0030001 metal ion transport;GO:0015693 magnesium ion transport;GO:0010961 intracellular magnesium ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "D3ZM22-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZM60-1", "uniprot_id": "D3ZM60_RAT", "mass": 122129.0, "length": 1096, "protein_name": "Protein phosphatase 1 regulatory subunit 3A", "gene_name": "Ppp1r3a", "organism": "Rat", "refseq_name": "protein phosphatase 1 regulatory subunit 3A", "refseq_ac": "NP_001102692", "gene_names_uniprotkb": "Ppp1r3a", "gene_names_refseq": "Ppp1r3a; RGD1561312", "protein_names_uniprotkb": "Protein phosphatase 1 regulatory subunit 3A; Protein phosphatase 1 glycogen-associated regulatory subunit; Protein phosphatase type-1 glycogen targeting subunit", "protein_names_refseq": "protein phosphatase 1 regulatory subunit 3A; protein phosphatase 1, regulatory (inhibitor) subunit 3A", "tax_id": 10116, "disease": "type 2 diabetes mellitus (Disease Ontology:DOID:9352); hypoglycemia (Disease Ontology:DOID:9993)", "pathway": " (rno:500036)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "22673903;26593335;31235787", "class_list": "", "function": "RNA sequencing after Ppp1r3a knockdown in primary cultured neonatal rat ventricular myocytes validates network-based predictions and establish Ppp1r3a as a central regulator in heart failure. Publication Status: Online-Only, [RefSeq, PubMed]; Rg1 through modulation of GDH and MFN2 maintained mitochondrial dynamics that resulted in protection against H/R-induced cardiomyocyte injury. All these results put forward a new protective mechanism of Rg1 on the therapeutic potential in cardiac I/R disorders., [RefSeq, PubMed]; Seems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Plays an important role in glycogen synthesis but is not essential for insulin activation of glycogen synthase., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008157 protein phosphatase 1 binding;GO:2001069 glycogen binding", "go_cellular_component": "GO:0000164 protein phosphatase type 1 complex", "go_biological_process": "GO:0005979 regulation of glycogen biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "D3ZM60-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZM97-1", "uniprot_id": "D3ZM97_RAT", "mass": 34788.0, "length": 313, "protein_name": "Olfactory receptor", "gene_name": "Or1m1", "organism": "Rat", "refseq_name": "olfactory receptor Olr1121", "refseq_ac": "NP_001000516", "gene_names_uniprotkb": "Or1m1", "gene_names_refseq": "Olr1121; Or1m1", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1121; olfactory receptor Olr1121; olfactory receptor gene Olr1121", "tax_id": 10116, "disease": "", "pathway": " (rno:315452)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZM97-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZME3-1", "uniprot_id": "D3ZME3_RAT", "mass": 22053.0, "length": 205, "protein_name": "glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)", "gene_name": "Gapdh-ps17", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Gapdh-ps17; LOC102552334", "gene_names_refseq": "", "protein_names_uniprotkb": "glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); 1.2.1.12; Peptidyl-cysteine S-nitrosylase GAPDH", "protein_names_refseq": "", "tax_id": 10116, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); lymphangioleiomyomatosis (Disease Ontology:DOID:3319)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.2.1.12;2.6.99.-", "go_molecular_function": "GO:0016740 transferase activity;GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005856 cytoskeleton", "go_biological_process": "GO:0006417 regulation of translation;GO:0006915 apoptotic process;GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZME3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZMH5-1", "uniprot_id": "D3ZMH5_RAT", "mass": 75843.0, "length": 657, "protein_name": "TCDD-inducible poly(ADP-ribose) polymerase", "gene_name": "Tiparp", "organism": "Rat", "refseq_name": "protein mono-ADP-ribosyltransferase TIPARP", "refseq_ac": "NP_001101149", "gene_names_uniprotkb": "Tiparp", "gene_names_refseq": "RM1; 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Or7g23e", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1132; olfactory receptor Olr1132; olfactory receptor gene Olr1132", "tax_id": 10116, "disease": "", "pathway": " (rno:405344)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZMP8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZMS3-1", "uniprot_id": "D3ZMS3_RAT", "mass": 68966.0, "length": 624, "protein_name": "Matrilin-4", "gene_name": "Matn4", "organism": "Rat", "refseq_name": "matrilin-4 precursor", "refseq_ac": "NP_001100009", "gene_names_uniprotkb": "Matn4", "gene_names_refseq": "Matn4", "protein_names_uniprotkb": "Matrilin-4", "protein_names_refseq": "matrilin-4 precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:296358)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Major component of the extracellular matrix of cartilage., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0031012 extracellular matrix;GO:0120216 matrilin complex", "go_biological_process": "GO:0048678 response to axon injury", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZMS3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZN06-1", "uniprot_id": "D3ZN06_RAT", "mass": 81827.0, "length": 764, "protein_name": "Endosialin", "gene_name": "Cd248", "organism": "Rat", "refseq_name": "endosialin precursor", "refseq_ac": "NP_001099795", "gene_names_uniprotkb": "Cd248; LOC100911882", "gene_names_refseq": "Cd164l1; Cd248", "protein_names_uniprotkb": "Endosialin; Tumor endothelial marker 1", "protein_names_refseq": "CD164 sialomucin-like 1; CD248 antigen, endosialin; CD248 molecule, endosialin; endosialin precursor; endosialin-like; endosialin", "tax_id": 10116, "disease": "", "pathway": " (rno:293669)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:1990430 extracellular matrix protein binding;GO:0005509 calcium ion binding;GO:0030246 carbohydrate binding;GO:0050840 extracellular matrix binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0016477 cell migration;GO:2000353 positive regulation of endothelial cell apoptotic process;GO:0048535 lymph node development;GO:0060033 anatomical structure regression", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZN06-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZN51-1", "uniprot_id": "D3ZN51_RAT", "mass": 126875.0, "length": 1156, "protein_name": "Integrin alpha-9", "gene_name": "Itga9", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Itga9", "gene_names_refseq": "", "protein_names_uniprotkb": "Integrin alpha-9", "protein_names_refseq": "", "tax_id": 10116, "disease": "congenital chylothorax (Disease Ontology:DOID:0060646); intellectual disability (Disease Ontology:DOID:1059); hypertension (Disease Ontology:DOID:10763); pancreatic cancer (Disease Ontology:DOID:1793); cerebral infarction (Disease Ontology:DOID:3526); lung non-small cell carcinoma (Disease Ontology:DOID:3908)", "pathway": " (rno:685004); (R-RNO-216083); (R-RNO-3000178); (R-RNO-445144)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Integrin alpha-9/beta-1 (ITGA9:ITGB1) is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. ITGA9:ITGB1 may play a crucial role in SVEP1/polydom-mediated myoblast cell adhesion. Integrin ITGA9:ITGB1 represses PRKCA-mediated L-type voltage-gated channel Ca(2+) influx and ROCK-mediated calcium sensitivity in vascular smooth muscle cells via its interaction with SVEP1, thereby inhibiting vasocontraction., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005518 collagen binding;GO:0043236 laminin binding;GO:0098640 integrin binding involved in cell-matrix adhesion;GO:0038023 signaling receptor activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0009986 cell surface;GO:0009925 basal plasma membrane;GO:0034679 integrin alpha9-beta1 complex;GO:0008305 integrin complex", "go_biological_process": "GO:0007155 cell adhesion;GO:0007229 integrin-mediated signaling pathway;GO:0098609 cell-cell adhesion;GO:0045906 negative regulation of vasoconstriction;GO:0030593 neutrophil chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZN51-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZN93-1", "uniprot_id": "D3ZN93_RAT", "mass": 14814.0, "length": 133, "protein_name": "Nescient helix loop helix 1", "gene_name": "Nhlh1", "organism": "Rat", "refseq_name": "helix-loop-helix protein 1", "refseq_ac": "NP_001099440", "gene_names_uniprotkb": "Nhlh1", "gene_names_refseq": "Nhlh1", "protein_names_uniprotkb": "Nescient helix loop helix 1", "protein_names_refseq": "helix-loop-helix protein 1", "tax_id": 10116, "disease": "", "pathway": " (rno:289230)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007417 central nervous system development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZN93-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZN99-1", "uniprot_id": "D3ZN99_RAT", "mass": 169651.0, "length": 1560, "protein_name": "Adhesion G protein-coupled receptor B2", "gene_name": "Adgrb2", "organism": "Rat", "refseq_name": "adhesion G protein-coupled receptor B2 precursor", "refseq_ac": "NP_001101384", "gene_names_uniprotkb": "Adgrb2", "gene_names_refseq": "Adgrb2; Bai2", "protein_names_uniprotkb": "Adhesion G protein-coupled receptor B2", "protein_names_refseq": "adhesion G protein-coupled receptor B2 precursor; brain-specific angiogenesis inhibitor 2", "tax_id": 10116, "disease": "", "pathway": " (rno:313058)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "22673903;38843836", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0045202 synapse", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0007186 G protein-coupled receptor signaling pathway;GO:0051965 positive regulation of synapse assembly;GO:0007422 peripheral nervous system development;GO:0016525 negative regulation of angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "D3ZN99-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZNF4-1", "uniprot_id": "D3ZNF4_RAT", "mass": 55671.0, "length": 514, "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "Tbl1xr1", "organism": "Rat", "refseq_name": "F-box-like/WD repeat-containing protein TBL1XR1 isoform 1", "refseq_ac": "NP_001102411", "gene_names_uniprotkb": "Tbl1xr1", "gene_names_refseq": "RGD1560053; Tbl1xr1", "protein_names_uniprotkb": "F-box-like/WD repeat-containing protein TBL1XR1; Nuclear receptor corepressor/HDAC3 complex subunit TBLR1; TBL1-related protein 1; Transducin beta-like 1X-related protein 1", "protein_names_refseq": "F-box-like/WD repeat-containing protein TBL1XR1 isoform 1; F-box-like/WD repeat-containing protein TBL1XR1; TBL1X receptor 1; transducin (beta)-like 1 X-linked receptor 1", "tax_id": 10116, "disease": "sensory system disease (Disease Ontology:DOID:0050155); autosomal dominant intellectual developmental disorder 41 (Disease Ontology:DOID:0070071); Pierpont syndrome (Disease Ontology:DOID:0081362)", "pathway": " (rno:365755); (R-RNO-3214815); (R-RNO-350054); (R-RNO-400206); (R-RNO-9029569); (R-RNO-9707564); (R-RNO-9841922)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "29393594", "class_list": "", "function": "F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003714 transcription corepressor activity;GO:0000976 transcription cis-regulatory region binding;GO:0008013 beta-catenin binding;GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus;GO:0017053 transcription repressor complex;GO:0000118 histone deacetylase complex;GO:0072686 mitotic spindle", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0050872 white fat cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZNF4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZNF5-1", "uniprot_id": "TM63C_RAT", "mass": 92962.0, "length": 802, "protein_name": "Osmosensitive cation channel TMEM63C", "gene_name": "Tmem63c", "organism": "Rat", "refseq_name": "osmosensitive cation channel TMEM63C", "refseq_ac": "NP_001101515", "gene_names_uniprotkb": "Tmem63c; Csc1", "gene_names_refseq": "RGD1310207; Tmem63c", "protein_names_uniprotkb": "Osmosensitive cation channel TMEM63C; Calcium permeable stress-gated cation channel 1; Transmembrane protein 63C", "protein_names_refseq": "calcium permeable stress-gated cation channel 1; osmosensitive cation channel TMEM63C", "tax_id": 10116, "disease": "hereditary spastic paraplegia 87 (Disease Ontology:DOID:0070456); focal segmental glomerulosclerosis (Disease Ontology:DOID:1312); central nervous system disease (Disease Ontology:DOID:331)", "pathway": " (rno:314332)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "22673903;30900988", "class_list": "", "function": "Acts as an osmosensitive cation channel preferentially activated upon hypotonic stress (By similarity). In contrast to TMEM63B, does not show phospholipid scramblase activity (By similarity). Enriched in mitochondria-ER contact sites where it may regulate the metabolite flux and organelles' morphologies in response to osmotic changes (By similarity). In particular may regulate mitochondrial motility and function in motor neuron axons (By similarity). Required for the functional integrity of the kidney glomerular filtration barrier (PubMed:30900988)., [UniProtKB, UniProtKB, PubMed]; Tmem63c is differentially expressed in glomeruli of allele-specific rat models during onset of albuminuria. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1", "go_molecular_function": "GO:0005227 calcium-activated cation channel activity;GO:1990760 osmolarity-sensing monoatomic cation channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005765 lysosomal membrane;GO:0005789 endoplasmic reticulum membrane;GO:0016020 membrane", "go_biological_process": "GO:0006812 monoatomic cation transport;GO:0003094 glomerular filtration", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZNF5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZNR0-1", "uniprot_id": "D3ZNR0_RAT", "mass": 17396.0, "length": 162, "protein_name": "Reproductive homeobox like", "gene_name": "Rhoxl", "organism": "Rat", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Rhoxl; RGD1560927", "gene_names_refseq": "", "protein_names_uniprotkb": "Reproductive homeobox like", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0048666 neuron development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZNR0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZNT5-1", "uniprot_id": "D3ZNT5_RAT", "mass": 65414.0, "length": 688, "protein_name": "Collagen type IX alpha 2 chain", "gene_name": "Col9a2", "organism": "Rat", "refseq_name": "collagen alpha-2(IX) chain precursor", "refseq_ac": "NP_001102145", "gene_names_uniprotkb": "Col9a2", "gene_names_refseq": "Col9a2", "protein_names_uniprotkb": "Collagen type IX alpha 2 chain", "protein_names_refseq": "alpha 1 type IX collagen; collagen alpha-2(IX) chain precursor; collagen alpha-2(IX) chain; collagen, type IX, alpha 2; procollagen, type IX, alpha 2", "tax_id": 10116, "disease": "multiple epiphyseal dysplasia 2 (Disease Ontology:DOID:0070298); Stickler syndrome (Disease Ontology:DOID:0080046); osteochondrodysplasia (Disease Ontology:DOID:2256)", "pathway": " (rno:362584); (R-RNO-1650814)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0030020 extracellular matrix structural constituent conferring tensile strength", "go_cellular_component": "GO:0031012 extracellular matrix;GO:0005594 collagen type IX trimer", "go_biological_process": "GO:0030198 extracellular matrix organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZNT5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZNU0-1", "uniprot_id": "D3ZNU0_RAT", "mass": 41580.0, "length": 379, "protein_name": "RING finger protein 215", "gene_name": "Rnf215", "organism": "Rat", "refseq_name": "RING finger protein 215 isoform 1 precursor", "refseq_ac": "NP_001100704", "gene_names_uniprotkb": "Rnf215", "gene_names_refseq": "RGD1310738; Rnf215", "protein_names_uniprotkb": "RING finger protein 215", "protein_names_refseq": "RING finger protein 215 isoform 1 precursor", "tax_id": 10116, "disease": "", "pathway": " (rno:305478)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZNU0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZNU4-1", "uniprot_id": "D3ZNU4_RAT", "mass": 59286.0, "length": 532, "protein_name": "Zinc finger protein 280B", "gene_name": "Zfp280b", "organism": "Rat", "refseq_name": "zinc finger protein 280B", "refseq_ac": "NP_001406443", "gene_names_uniprotkb": "Zfp280b", "gene_names_refseq": "RGD1565460; Zfp280b; Znf280b", "protein_names_uniprotkb": "Zinc finger protein 280B", "protein_names_refseq": "zinc finger protein 280B", "tax_id": 10116, "disease": "", "pathway": " (rno:294343)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22673903", "class_list": "", "function": "May function as a transcription factor., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZNU4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZNV1-1", "uniprot_id": "D3ZNV1_RAT", "mass": 35771.0, "length": 314, "protein_name": "Olfactory receptor", "gene_name": "Or6b6", "organism": "Rat", "refseq_name": "olfactory receptor Olr224", "refseq_ac": "NP_001000553", "gene_names_uniprotkb": "Or6b6", "gene_names_refseq": "Olr224; Or6b6", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 224; olfactory receptor Olr224; olfactory receptor gene Olr224", "tax_id": 10116, "disease": "", "pathway": " (rno:365342)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZNV1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZP31-1", "uniprot_id": "D3ZP31_RAT", "mass": 112976.0, "length": 982, "protein_name": "NLR family, pyrin domain containing 4", "gene_name": "Nlrp4", "organism": "Rat", "refseq_name": "NLR family, pyrin domain containing 4", "refseq_ac": "NP_001165635", "gene_names_uniprotkb": "Nlrp4", "gene_names_refseq": "Nalp4; Nlrp4e; Nlrp4; RGD1563529; RGD1564841", "protein_names_uniprotkb": "NLR family, pyrin domain containing 4", "protein_names_refseq": "NACHT, leucine rich repeat and PYD containing 4; NLR family, pyrin domain containing 4E; NLR family, pyrin domain containing 4", "tax_id": 10116, "disease": "", "pathway": " (rno:499069); (R-RNO-3134975); (R-RNO-3270619)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "28486191", "class_list": "", "function": "May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors., [UniProtKB, UniProtKB]; NLRP4 is an important mediator of cardiac remodeling in vitro and in vivo., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0061702 canonical inflammasome complex", "go_biological_process": "GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0050727 regulation of inflammatory response;GO:0045824 negative regulation of innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "D3ZP31-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZP67-1", "uniprot_id": "D3ZP67_RAT", "mass": 78818.0, "length": 707, "protein_name": "Protein phosphatase 1, regulatory subunit 15B", "gene_name": "Ppp1r15b", "organism": "Rat", "refseq_name": "protein phosphatase 1 regulatory subunit 15B", "refseq_ac": "NP_001100645", "gene_names_uniprotkb": "Ppp1r15b", "gene_names_refseq": "Ppp1r15b", "protein_names_uniprotkb": "Protein phosphatase 1, regulatory subunit 15B", "protein_names_refseq": "protein phosphatase 1 regulatory subunit 15B; 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Zinc finger AN1-type-containing protein 1", "protein_names_refseq": "", "tax_id": 10116, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in the regulation of cytoplasmic stress granules (SGs) turnover. SGs are dynamic and transient cytoplasmic ribonucleoprotein assemblies important for cellular protein homeostasis when protein production is suspended after acute exogenous stress. Associates with SGs and is involved in the efficient and specific arsenite-induced clearance process of SGs through the recruitment of the ubiquitin-selective ATPase VCP and the 26S proteasome. This process requires both complexes for efficient degradation of damaged ubiquitinated SG proteins during recovery from arsenite stress, and hence avoiding aberrant cytoplasmic SGs degradation via autophagy., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0070628 proteasome binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0090316 positive regulation of intracellular protein transport;GO:0035617 stress granule disassembly;GO:1903843 cellular response to arsenite ion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZQI4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZQL9-1", "uniprot_id": "D3ZQL9_RAT", "mass": 37651.0, "length": 351, "protein_name": "Atonal bHLH transcription factor 1", "gene_name": "Atoh1", "organism": "Rat", "refseq_name": "transcription factor ATOH1", "refseq_ac": "NP_001102708", "gene_names_uniprotkb": "Atoh1", "gene_names_refseq": "Atoh1; RGD1565171", "protein_names_uniprotkb": "Atonal bHLH transcription factor 1", "protein_names_refseq": "protein atonal homolog 1; transcription factor ATOH1", "tax_id": 10116, "disease": "autosomal dominant nonsyndromic deafness 89 (Disease Ontology:DOID:0070612)", "pathway": " (rno:500156)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "22423092;23669638;28576729;31945449", "class_list": "", "function": "Atoh1 mediates trans-differentiation of morphological and functional 'ancestral' hair cells that are likely to undergo diversification in an endorgan-specific manner., [RefSeq, PubMed]; Cochlear explants of auditory epithelia with native spiral ganglion neurons (SGNs) retained were cultured in vitro, and genetic vectors encoding Atoh1 were used to overexpress Atoh1 and induce ectopic hair-cell-like cells (EHCLCs). The neurites of the original SGNs extended toward the lesser epithelial ridge and innervated the EHCLCs., [RefSeq, PubMed]; Math1 induced hair cell-like cells from lateral epithelial ridge cells mainly underwent direct trans-differentiation instead of mitosis of LER cells or newly hair cell-like cells., [RefSeq, PubMed]; The Atoh1 expression levels are correlated with the arrangement, ciliary morphology, and electrophysiological characteristics of ectopic hair cell-like cells., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0046983 protein dimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0031490 chromatin DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0042491 inner ear auditory receptor cell differentiation;GO:0014014 negative regulation of gliogenesis;GO:0006351 DNA-templated transcription;GO:0007219 Notch signaling pathway;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "D3ZQL9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZQM0-1", "uniprot_id": "D3ZQM0_RAT", "mass": 88588.0, "length": 791, "protein_name": "Splicing factor 3A subunit 1", "gene_name": "Sf3a1", "organism": "Rat", "refseq_name": "splicing factor 3A subunit 1", "refseq_ac": "NP_001100705", "gene_names_uniprotkb": "Sf3a1", "gene_names_refseq": "Sf3a1", "protein_names_uniprotkb": "Splicing factor 3A subunit 1; SF3a120", "protein_names_refseq": "splicing factor 3A subunit 1", "tax_id": 10116, "disease": "", "pathway": " (rno:305479); (R-RNO-72163); (R-RNO-9770562); (R-RNO-9943411)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "18683930;22673903;34502162", "class_list": "", "function": "Component of the 17S U2 SnRNP complex of the spliceosome, a large ribonucleoprotein complex that removes introns from transcribed pre-mRNAs. The 17S U2 SnRNP complex (1) directly participates in early spliceosome assembly and (2) mediates recognition of the intron branch site during pre-mRNA splicing by promoting the selection of the pre-mRNA branch-site adenosine, the nucleophile for the first step of splicing. Within the 17S U2 SnRNP complex, SF3A1 is part of the SF3A subcomplex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex. Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0016607 nuclear speck;GO:0005681 spliceosomal complex;GO:0071013 catalytic step 2 spliceosome", "go_biological_process": "GO:0006397 mRNA processing;GO:0000398 mRNA splicing, via spliceosome;GO:0045292 mRNA cis splicing, via spliceosome;GO:1903241 U2-type prespliceosome assembly", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "D3ZQM0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZQN5-1", "uniprot_id": "D3ZQN5_RAT", "mass": 24881.0, "length": 221, "protein_name": "Myomaker, myoblast fusion factor", "gene_name": "Mymk", "organism": "Rat", "refseq_name": "protein myomaker", "refseq_ac": "NP_001386244", "gene_names_uniprotkb": "Mymk; Tmem8c", "gene_names_refseq": "Mymk; RGD1306074; Tmem8c", "protein_names_uniprotkb": "Myomaker, myoblast fusion factor", "protein_names_refseq": "protein myomaker; transmembrane protein 8C", "tax_id": 10116, "disease": "Carey-Fineman-Ziter syndrome 1 (Disease Ontology:DOID:0061115)", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0043403 skeletal muscle tissue regeneration;GO:0007520 myoblast fusion;GO:1904206 positive regulation of skeletal muscle hypertrophy;GO:0014905 myoblast fusion involved in skeletal muscle regeneration;GO:0045026 plasma membrane fusion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZQN5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZQP2-1", "uniprot_id": "D3ZQP2_RAT", "mass": 48231.0, "length": 421, "protein_name": "BEN domain-containing protein 5", "gene_name": "Agbl4; Bend5", "organism": "Rat", "refseq_name": "BEN domain-containing protein 5", "refseq_ac": "NP_001102142", "gene_names_uniprotkb": "Agbl4; Bend5; Agbl4; Bend5", "gene_names_refseq": "Bend5", "protein_names_uniprotkb": "BEN domain-containing protein 5", "protein_names_refseq": "BEN domain-containing protein 5", "tax_id": 10116, "disease": "", "pathway": " (rno:362564)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a transcriptional repressor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0004181 metallocarboxypeptidase activity;GO:0015631 tubulin binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0005814 centriole;GO:1904115 axon cytoplasm;GO:0036064 ciliary basal body", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription;GO:0006508 proteolysis;GO:0008285 negative regulation of cell population proliferation;GO:0051607 defense response to virus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "D3ZQP2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZQP6-1", "uniprot_id": "D3ZQP6_RAT", "mass": 75144.0, "length": 666, "protein_name": "Semaphorin-7A", "gene_name": "Sema7a", "organism": "Rat", "refseq_name": "semaphorin-7A precursor", "refseq_ac": "NP_001101623", "gene_names_uniprotkb": "Sema7a", "gene_names_refseq": "Sema7a", "protein_names_uniprotkb": "Semaphorin-7A; Semaphorin-K1; Semaphorin-L", "protein_names_refseq": "sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A; semaphorin 7A, GPI membrane anchor; semaphorin-7A precursor; semaphorin-7A", "tax_id": 10116, "disease": "progressive familial intrahepatic cholestasis (Disease Ontology:DOID:0070221)", "pathway": " (rno:315711); (R-RNO-416700)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "17727705;20645410;24090084;25353180;25721933;27858721;28765893;29393594;31179640", "class_list": "", "function": "After spinal cord injury, Sema7A-positive cells accumulate specifically in lesion areas resulting in significantly enhanced Sema7A expression at the injury site., [RefSeq, PubMed]; Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of pro-inflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes., [UniProtKB, UniProtKB]; SEMA7A is critical in the development of lung inflammation and pulmonary edema in seawater aspiration-induced ALI, and may be a therapeutic target for this disease. Publication Status: Online-Only, [RefSeq, PubMed]; SEMA7A promotes seawater induced lung edema via plexin C1 and stimulates seawater induced lung inflammation via beta1 integrin., [RefSeq, PubMed]; Sema7A and plexinC1 expression patterns are consistent with these proteins serving both cooperative and separate functions during neural development Publication Status: Online-Only, [RefSeq, PubMed]; Sema7A, a brain immune regulator, regulates seizure activity in PTZ-kindled epileptic rats., [RefSeq, PubMed]; Semaphorin7A regulates neuroglial plasticity in the adult hypothalamic median eminence. Publication Status: Online-Only, [RefSeq, PubMed]; This study shown that mrna of expression of semaphorin 7A after cell therapy in a mouse model of Parkinson's disease., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 1, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 3, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 9, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005178 integrin binding;GO:0030215 semaphorin receptor binding;GO:0045499 chemorepellent activity", "go_cellular_component": "GO:0098982 GABA-ergic synapse;GO:0005886 plasma membrane;GO:0009897 external side of plasma membrane;GO:0098793 presynapse", "go_biological_process": "GO:0001934 positive regulation of protein phosphorylation;GO:0006954 inflammatory response;GO:0007229 integrin-mediated signaling pathway;GO:0030335 positive regulation of cell migration;GO:0031175 neuron projection development", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "D3ZQP6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZQV0-1", "uniprot_id": "D3ZQV0_RAT", "mass": 26266.0, "length": 246, "protein_name": "trypsin", "gene_name": "Prss3", "organism": "Rat", "refseq_name": "serine protease 3 precursor", "refseq_ac": "NP_001102096", "gene_names_uniprotkb": "Prss3; LOC100365995; Try4", "gene_names_refseq": "Prss3; Try4", "protein_names_uniprotkb": "trypsin; 3.4.21.4", "protein_names_refseq": "protease, serine 3; protease, serine, 3 (mesotrypsin); serine protease 3 precursor; trypsin 4", "tax_id": 10116, "disease": "cholangiocarcinoma (Disease Ontology:DOID:4947); pancreatitis (Disease Ontology:DOID:4989)", "pathway": " (rno:362347); (R-RNO-1442490); (R-RNO-1462054); (R-RNO-1592389); (R-RNO-6798695); (R-RNO-6803157)", "pathway_count": 6, "publication_count": 2, "publication_id_list": "16903872;17623652", "class_list": "", "function": "Brain-specific mesotrypsin, via the regulation of PAR-1, is likely to be involved in multiple physiological/pathological processes in the brain, [RefSeq, PubMed]; Trypsin IV and p23 are inhibitor-resistant trypsins that can cleave and activate PARs, causing PAR(1)- and PAR(2)-dependent inflammation and PAR(2)-dependent hyperalgesia., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.11.2.2;3.4.21.4;3.4.16.-;3.2.1.-;5.3.4.1;1.1.1.205;3.4.24.7;3.2.1.23;3.5.4.5;2.3.2.5;5.3.99.3;1.11.1.27;3.1.1.4;2.3.1.23;3.4.24.34;3.2.1.17;3.4.24.17;4.1.2.13;3.2.1.31;3.4.24.22;3.4.21.1;3.5.3.1;2.7.11.13;3.4.21.34;2.3.3.8;3.2.1.51;3.4.21.20;1.16.3.1;1.6.2.2;3.5.3.15;3.4.24.-;3.4.23.5;3.3.2.6;3.4.11.4;3.5.1.26;5.4.2.2;1.1.1.42;3.6.4.6;3.4.24.23;3.4.24.35;3.4.21.39;3.4.21.59;3.1.6.12;2.4.1.1;2.7.11.24;3.1.27.-;3.4.14.1;3.1.3.48;3.4.22.27;3.1.6.4;3.1.6.8;1.6.5.5;3.5.1.3;3.6.1.-;2.7.10.2;3.4.19.9;3.1.3.16;3.2.1.52;1.8.3.2;3.5.1.23;3.5.1.-;6.3.4.21;3.6.1.6;3.4.14.2", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0005509 calcium ion binding;GO:0008236 serine-type peptidase activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006508 proteolysis;GO:0043542 endothelial cell migration;GO:0031638 zymogen activation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D3ZQV0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3ZQV2-1", "uniprot_id": "D3ZQV2_RAT", "mass": 117783.0, "length": 1054, "protein_name": "Leucine-rich repeats and immunoglobulin-like domains protein 2", "gene_name": "Lrig2", "organism": "Rat", "refseq_name": "leucine-rich repeats and immunoglobulin-like domains protein 2 precursor", "refseq_ac": "NP_001101180", "gene_names_uniprotkb": "Lrig2", "gene_names_refseq": "Lrig2", "protein_names_uniprotkb": "Leucine-rich repeats and immunoglobulin-like domains protein 2", "protein_names_refseq": "leucine-rich repeats and immunoglobulin-like domains protein 2 precursor; 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