{
    "disease_id": "DOID:0050453",
    "recommended_name": {
        "id": "DOID:0050453",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0050453",
        "name": "lissencephaly",
        "description": "A congenital nervous system abnormality characterized by the absence of folds in the cerebral cortex and caused_by defective neuronal migration during the 12th to 24th weeks of gestation."
    },
    "synonyms": [
        {
            "id": "MONDO:0011830",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011830",
            "name": "lissencephaly due to LIS1 mutation",
            "description": "Lissencephaly due to LIS1 mutation is a cerebral malformation with epilepsy characterized predominantly by posterior isolated lissencephaly with developmental delay, intellectual disability and epilepsy that usually evolves from West syndrome to Lennox-Gastaut syndrome. Additional features include muscular hypotonia, acquired microcephaly, failure to thrive and poor control of airways leading to aspiration pneumonia."
        },
        {
            "id": "MONDO:0011830",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011830",
            "name": "PAFAH1B1-related lissencephaly",
            "description": ""
        },
        {
            "id": "MONDO:0011830",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011830",
            "name": "LIS1",
            "description": ""
        },
        {
            "id": "MONDO:0011830",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011830",
            "name": "lissencephaly 1",
            "description": ""
        },
        {
            "id": "MIM:607432",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/607432",
            "name": "Subcortical band heterotopia",
            "description": "Subcortical band heterotopia"
        }
    ],
    "children": [
        {
            "id": "DOID:0060902",
            "label": "Norman-Roberts syndrome",
            "link_status": true,
            "children": []
        },
        {
            "id": "DOID:0112228",
            "label": "lissencephaly 9 with complex brainstem malformation",
            "link_status": true,
            "children": []
        },
        {
            "id": "DOID:0112229",
            "label": "lissencephaly 10",
            "link_status": true,
            "children": []
        },
        {
            "id": "DOID:0112230",
            "label": "leukoencephalopathy with variable cortical brain malformations and/or hydrocephalus",
            "link_status": true,
            "children": []
        },
        {
            "id": "DOID:0112231",
            "label": "lissencephaly 7 with cerebellar hypoplasia",
            "link_status": true,
            "children": []
        },
        {
            "id": "DOID:0112232",
            "label": "lissencephaly 3",
            "link_status": true,
            "children": []
        },
        {
            "id": "DOID:0112233",
            "label": "lissencephaly 8",
            "link_status": true,
            "children": []
        },
        {
            "id": "DOID:0112234",
            "label": "microlissencephaly",
            "link_status": true,
            "children": [
                {
                    "id": "DOID:0112235",
                    "label": "lissencephaly 4",
                    "link_status": true,
                    "children": []
                },
                {
                    "id": "DOID:0112236",
                    "label": "lissencephaly 6",
                    "link_status": true,
                    "children": []
                }
            ]
        },
        {
            "id": "DOID:0112237",
            "label": "lissencephaly 1",
            "link_status": true,
            "children": []
        },
        {
            "id": "DOID:0112238",
            "label": "X-linked lissencephaly 2",
            "link_status": true,
            "children": []
        },
        {
            "id": "DOID:0112239",
            "label": "X-linked lissencephaly 1",
            "link_status": true,
            "children": []
        }
    ],
    "id_list": [
        "DOID:0112234",
        "DOID:0050453",
        "DOID:0112235",
        "DOID:0112233",
        "DOID:0112239",
        "DOID:0112231",
        "DOID:0112232",
        "DOID:0060902",
        "DOID:0112236",
        "DOID:0112237",
        "DOID:0112229",
        "DOID:0112238",
        "DOID:0112228",
        "DOID:0112230"
    ],
    "unlinked_id_list": []
}