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"uniprot_canonical_ac": "A0ABI0NQQ4-1", "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "length": 559, "chemical_mass": 64006.0, "gene_names": "PRKAA1;PRKAA1", "protein_name": "5'-AMP-activated protein kinase catalytic subunit alpha-1", "disease": [], "biological_process": [ { "name": "negative regulation of hepatocyte apoptotic process", "id": "GO:1903944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903944", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "positive regulation of T cell mediated immune response to tumor cell", "id": "GO:0002842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002842", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "positive regulation of adipose tissue development", "id": "GO:1904179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904179", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "response to gamma radiation", "id": "GO:0010332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010332", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "neuron cellular homeostasis", "id": "GO:0070050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070050", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "cellular response to glucose stimulus", "id": "GO:0071333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071333", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "positive regulation of protein targeting to mitochondrion", "id": "GO:1903955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903955", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "negative regulation of lipid catabolic process", "id": "GO:0050995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050995", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "energy homeostasis", "id": "GO:0097009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097009", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "response to hydrogen peroxide", "id": "GO:0042542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042542", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "cellular response to calcium ion", "id": "GO:0071277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071277", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "cholesterol biosynthetic process", "id": "GO:0006695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006695", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "regulation of vascular permeability", "id": "GO:0043114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043114", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "response to UV", "id": "GO:0009411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009411", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "cellular response to glucose starvation", "id": "GO:0042149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042149", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "regulation of circadian rhythm", "id": "GO:0042752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042752", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "rhythmic process", "id": "GO:0048511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048511", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "CAMKK-AMPK signaling cascade", "id": "GO:0061762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061762", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "positive regulation of T cell activation", "id": "GO:0050870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050870", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "negative regulation of TORC1 signaling", "id": "GO:1904262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904262", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "regulation of microtubule cytoskeleton organization", "id": "GO:0070507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070507", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "positive regulation of protein localization", "id": "GO:1903829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903829", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "protein localization to lipid droplet", "id": "GO:1990044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990044", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "motor behavior", "id": "GO:0061744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061744", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "regulation of stress granule assembly", "id": "GO:0062028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062028", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "positive regulation of mitochondrial transcription", "id": "GO:1903109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903109", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "positive regulation of catabolic process", "id": "GO:0009896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009896", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "AMP-activated protein kinase activity", "id": "GO:0004679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004679", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity", "id": "GO:0047322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047322", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "tau-protein kinase activity", "id": "GO:0050321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050321", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "histone H2BS36 kinase activity", "id": "GO:0140823", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140823", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "protein serine 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