[ { "uniprot_canonical_ac": "A1ZBU6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZBU6", "url": "https://www.uniprot.org/uniprotkb/A1ZBU6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 282, "chemical_mass": 27906.0, "gene_names": "BcDNA:RE70748;BcDNA:RE70748;CG30151;Dmel\\CG30151;Dmel_CG30151", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1ZBU6-1" }, { "uniprot_canonical_ac": "A1ZBU9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZBU9", "url": "https://www.uniprot.org/uniprotkb/A1ZBU9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 476, "chemical_mass": 54220.0, "gene_names": "Dmel\\CG13423;CG13423;Dmel\\CG13423;Dmel_CG13423", "protein_name": "Bleomycin hydrolase", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1ZBU9", "url": "https://www.uniprot.org/uniprotkb/A1ZBU9" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A1ZBU9", "url": "https://www.uniprot.org/uniprotkb/A1ZBU9" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A1ZBU9", "url": "https://www.uniprot.org/uniprotkb/A1ZBU9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1ZBU9-1" }, { "uniprot_canonical_ac": "A1ZBV0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZBV0", "url": "https://www.uniprot.org/uniprotkb/A1ZBV0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 105, "chemical_mass": 11677.0, "gene_names": "Dmel\\CG13427;CG13427;Dmel\\CG13427;Dmel_CG13427", "protein_name": "", "disease": [], "cellular_component": [ { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "A1ZBV0", "url": "https://www.uniprot.org/uniprotkb/A1ZBV0" } ], "pmid": "" } ], "biological_process": [ { "name": "gastrulation", "id": "GO:0007369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007369", "evidence": [ { "database": "UniProtKB", "id": "A1ZBV0", "url": "https://www.uniprot.org/uniprotkb/A1ZBV0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1ZBV0-1" }, { "uniprot_canonical_ac": "A8DYA9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8DYA9", "url": "https://www.uniprot.org/uniprotkb/A8DYA9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 129, "chemical_mass": 14631.0, "gene_names": "Dmel\\CG34230;CG34230;Dmel\\CG34230;Dmel_CG34230", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8DYA9-1" }, { "uniprot_canonical_ac": "A8DYC6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8DYC6", "url": "https://www.uniprot.org/uniprotkb/A8DYC6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 266, "chemical_mass": 31192.0, "gene_names": "Dmel\\CG34315;CG34315;Dmel\\CG34315;Dmel_CG34315", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8DYC6-1" }, { "uniprot_canonical_ac": "A8DYP7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 459, "chemical_mass": 53811.0, "gene_names": "cGlr2;CG30424;Dmel\\CG30424;cGLR2;cGlr2;mdcds_18556", "protein_name": "Cyclic GMP-AMP synthase-like receptor 2", "disease": [], "molecular_function": [ { "name": "2',3'-cyclic GMP-AMP synthase activity", "id": "GO:0061501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061501", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" } ], "pmid": "" }, { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" } ], "pmid": "" }, { "name": "3',2'-cyclic GMP-AMP synthase activity", "id": "GO:0140700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140700", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" } ], "pmid": "" } ], "biological_process": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" } ], "pmid": "" }, { "name": "cellular response to virus", "id": "GO:0098586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098586", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" } ], "pmid": "" }, { "name": "immune response involved in response to exogenous dsRNA", "id": "GO:1902615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902615", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" } ], "pmid": "" }, { "name": "cGAS/STING signaling pathway", "id": "GO:0140896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140896", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A8DYP7-1", "start_pos": "256", "end_pos": "256", "site_lbl": "Lys256", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "E", "comment": "Abolished binding to nucleic acid activator, leading to impaired antiviral immunity; when associated with E-267 or E-271.", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" }, { "database": "PubMed", "id": "34261128", "url": "https://glygen.org/publication/PubMed/34261128" } ] } ] }, { "uniprot_canonical_ac": "A8DYP7-1", "start_pos": "267", "end_pos": "267", "site_lbl": "Arg267", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "E", "comment": "Abolished binding to nucleic acid activator, leading to impaired antiviral immunity; when associated with E-256.", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" }, { "database": "PubMed", "id": "34261128", "url": "https://glygen.org/publication/PubMed/34261128" } ] } ] }, { "uniprot_canonical_ac": "A8DYP7-1", "start_pos": "271", "end_pos": "271", "site_lbl": "Arg271", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "E", "comment": "Abolished binding to nucleic acid activator, leading to impaired antiviral immunity; when associated with E-256.", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" }, { "database": "PubMed", "id": "34261128", "url": "https://glygen.org/publication/PubMed/34261128" } ] } ] } ], "record_id": "A8DYP7-1" }, { "uniprot_canonical_ac": "A8DYU5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8DYU5", "url": "https://www.uniprot.org/uniprotkb/A8DYU5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 83, "chemical_mass": 9236.0, "gene_names": "Dmel\\CG34176;CG34176;Dmel\\CG34176;Dmel_CG34176", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8DYU5-1" }, { "uniprot_canonical_ac": "A8DYY2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8DYY2", "url": "https://www.uniprot.org/uniprotkb/A8DYY2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 203, "chemical_mass": 23384.0, "gene_names": "Dmel\\CG34181;CG34181;Dmel\\CG34181;Dmel_CG34181", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8DYY2-1" }, { "uniprot_canonical_ac": "A8JNI2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JNI2", "url": "https://www.uniprot.org/uniprotkb/A8JNI2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1655, "chemical_mass": 185904.0, "gene_names": "Srrm234;BcDNA:GH04236;CG7971;Dmel\\CG7971;Dmel_CG7971;SRm300;Srrm234;anon-EST:fe1A7", "protein_name": "", "disease": [ { "disease_id": "DOID:0061045", "name": "autosomal dominant intellectual developmental disorder 72", "description": "An autosomal dominant intellectual developmental disorder characterized by developmental delay, predominant speech delay, autistic or attention-deficit/hyperactivity disorder features, overfriendliness, generalized hypotonia, overweight/obesity, and dysmorphic features that has_material_basis_in heterozygous mutation in the SRRM2 gene on chromosome 16p13.", "url": "https://disease-ontology.org/term/DOID:0061045", "evidence": [ { "id": "0061045", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061045" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A8JNI2", "url": "https://www.uniprot.org/uniprotkb/A8JNI2" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "A8JNI2", "url": "https://www.uniprot.org/uniprotkb/A8JNI2" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "A8JNI2", "url": "https://www.uniprot.org/uniprotkb/A8JNI2" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A8JNI2", "url": "https://www.uniprot.org/uniprotkb/A8JNI2" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A8JNI2", "url": "https://www.uniprot.org/uniprotkb/A8JNI2" } ], "pmid": "" }, { "name": "alternative mRNA splicing, via spliceosome", "id": "GO:0000380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000380", "evidence": [ { "database": "UniProtKB", "id": "A8JNI2", "url": "https://www.uniprot.org/uniprotkb/A8JNI2" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A8JNI2", "url": "https://www.uniprot.org/uniprotkb/A8JNI2" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A8JNI2", "url": "https://www.uniprot.org/uniprotkb/A8JNI2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A8JNI2-1", "start_pos": "916", "end_pos": "916", "site_lbl": "Thr916", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 916, "start_aa": "Thr", "end_pos": 916, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr916", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A8JNI2-1" }, { "uniprot_canonical_ac": "A8JNM1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JNM1", "url": "https://www.uniprot.org/uniprotkb/A8JNM1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1717, "chemical_mass": 188938.0, "gene_names": "form3;CG14824;CG18138;CG32384;CG33556;CG8633;DIA-like;Dmel\\CG33556;Dmel_CG33556;Form3;Formin3;INF2;ah1644;form3;formin/DIA-like;form", "protein_name": "", "disease": [ { "disease_id": "DOID:0110205", "name": "Charcot-Marie-Tooth disease dominant intermediate E", "description": "A Charcot-Marie-Tooth disease intermediate type that has_material_basis_in heterozygous mutation in the INF2 gene on chromosome 14q32.", "url": "https://disease-ontology.org/term/DOID:0110205", "evidence": [ { "id": "0110205", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110205" } ], "weight": 0.0 }, { "disease_id": "DOID:0111130", "name": "focal segmental glomerulosclerosis 5", "description": "A focal segmental glomerulosclerosis that has_material_basis_in an autosomal dominant mutation of the INF2 gene on chromosome 14q32.33.", "url": "https://disease-ontology.org/term/DOID:0111130", "evidence": [ { "id": "0111130", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111130" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A8JNM1", "url": "https://www.uniprot.org/uniprotkb/A8JNM1" } ], "pmid": "" } ], "biological_process": [ { "name": "branch fusion, open tracheal system", "id": "GO:0035147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035147", "evidence": [ { "database": "UniProtKB", "id": "A8JNM1", "url": "https://www.uniprot.org/uniprotkb/A8JNM1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A8JNM1-1", "start_pos": "171", "end_pos": "171", "site_lbl": "Thr171", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 171, "start_aa": "Thr", "end_pos": 171, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr171", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A8JNM1-1" }, { "uniprot_canonical_ac": "A8JNP7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JNP7", "url": "https://www.uniprot.org/uniprotkb/A8JNP7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 310, "chemical_mass": 34379.0, "gene_names": "I-2;CG10574;DI-2;Dm I-2;Dmel\\CG10574;Dmel_CG10574;I-2Dm;I-2PP1;I-2;I2;SET", "protein_name": "", "disease": [], "biological_process": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A8JNP7", "url": "https://www.uniprot.org/uniprotkb/A8JNP7" } ], "pmid": "" }, { "name": "positive regulation of BMP signaling pathway", "id": "GO:0030513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030513", "evidence": [ { "database": "UniProtKB", "id": "A8JNP7", "url": "https://www.uniprot.org/uniprotkb/A8JNP7" } ], "pmid": "" }, { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "A8JNP7", "url": "https://www.uniprot.org/uniprotkb/A8JNP7" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein phosphatase 1 binding", "id": "GO:0008157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008157", "evidence": [ { "database": "UniProtKB", "id": "A8JNP7", "url": "https://www.uniprot.org/uniprotkb/A8JNP7" } ], "pmid": "" }, { "name": "protein phosphatase inhibitor activity", "id": "GO:0004864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004864", "evidence": [ { "database": "UniProtKB", "id": "A8JNP7", "url": "https://www.uniprot.org/uniprotkb/A8JNP7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8JNP7-1" }, { "uniprot_canonical_ac": "A8JNQ7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JNQ7", "url": "https://www.uniprot.org/uniprotkb/A8JNQ7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 206, "chemical_mass": 23433.0, "gene_names": "Dmel\\CG34238;CG34238;Dmel\\CG34238;Dmel_CG34238", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8JNQ7-1" }, { "uniprot_canonical_ac": "A8JNS2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JNS2", "url": "https://www.uniprot.org/uniprotkb/A8JNS2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 247, "chemical_mass": 27983.0, "gene_names": "Dmel\\CG34428;CG14116;CG34428;Dmel_CG34428", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8JNS2-1" }, { "uniprot_canonical_ac": "A8JNS3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JNS3", "url": "https://www.uniprot.org/uniprotkb/A8JNS3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 249, "chemical_mass": 27862.0, "gene_names": "Dmel\\CG34429;CG14116;CG34429;Dmel\\CG34429;Dmel_CG34429", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8JNS3-1" }, { "uniprot_canonical_ac": "A8JPJ8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JPJ8", "url": "https://www.uniprot.org/uniprotkb/A8JPJ8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 421, "chemical_mass": 48616.0, "gene_names": "ppk31;CG31065;Dmel\\CG31065;Dmel_CG31065;Ppk31;ppk31", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A8JPJ8", "url": "https://www.uniprot.org/uniprotkb/A8JPJ8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A8JPJ8", "url": "https://www.uniprot.org/uniprotkb/A8JPJ8" } ], "pmid": "" } ], "biological_process": [ { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "A8JPJ8", "url": "https://www.uniprot.org/uniprotkb/A8JPJ8" } ], "pmid": "" }, { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "A8JPJ8", "url": "https://www.uniprot.org/uniprotkb/A8JPJ8" } ], "pmid": "" } ], "molecular_function": [ { "name": "sodium channel activity", "id": "GO:0005272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005272", "evidence": [ { "database": "UniProtKB", "id": "A8JPJ8", "url": "https://www.uniprot.org/uniprotkb/A8JPJ8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8JPJ8-1" }, { "uniprot_canonical_ac": "A8JQT2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JQT2", "url": "https://www.uniprot.org/uniprotkb/A8JQT2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 532, "chemical_mass": 63077.0, "gene_names": "CG12584;CG12584;CG34425;CG41467;Dmel\\CG34425;Dmel_CG34425", "protein_name": "Trichohyalin", "disease": [], "cellular_component": [ { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A8JQT2", "url": "https://www.uniprot.org/uniprotkb/A8JQT2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8JQT2-1" }, { "uniprot_canonical_ac": "A8JRF0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JRF0", "url": "https://www.uniprot.org/uniprotkb/A8JRF0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 266, "chemical_mass": 30212.0, "gene_names": "CG16918;CG16918;CG34437;Dmel\\CG34437;Dmel_CG34437;SPH201b;SPH201", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A8JRF0", "url": "https://www.uniprot.org/uniprotkb/A8JRF0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8JRF0-1" }, { "uniprot_canonical_ac": "A8JUR0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JUR0", "url": "https://www.uniprot.org/uniprotkb/A8JUR0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 563, "chemical_mass": 62479.0, "gene_names": "Dmel\\CG8028;CG8028;Dmel\\CG8028;Dmel_CG8028;MCT", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A8JUR0", "url": "https://www.uniprot.org/uniprotkb/A8JUR0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A8JUR0", "url": "https://www.uniprot.org/uniprotkb/A8JUR0" } ], "pmid": "" } ], "biological_process": [ { "name": "response to toxic substance", "id": "GO:0009636", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009636", "evidence": [ { "database": "UniProtKB", "id": "A8JUR0", "url": "https://www.uniprot.org/uniprotkb/A8JUR0" } ], "pmid": "" }, { "name": "monocarboxylic acid transport", "id": "GO:0015718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015718", "evidence": [ { "database": "UniProtKB", "id": "A8JUR0", "url": "https://www.uniprot.org/uniprotkb/A8JUR0" } ], "pmid": "" }, { "name": "renal tubular secretion", "id": "GO:0097254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097254", "evidence": [ { "database": "UniProtKB", "id": "A8JUR0", "url": "https://www.uniprot.org/uniprotkb/A8JUR0" } ], "pmid": "" } ], "molecular_function": [ { "name": "monocarboxylic acid transmembrane transporter activity", "id": "GO:0008028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008028", "evidence": [ { "database": "UniProtKB", "id": "A8JUR0", "url": "https://www.uniprot.org/uniprotkb/A8JUR0" } ], "pmid": "" }, { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A8JUR0", "url": "https://www.uniprot.org/uniprotkb/A8JUR0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8JUR0-1" }, { "uniprot_canonical_ac": "A8JUR3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JUR3", "url": "https://www.uniprot.org/uniprotkb/A8JUR3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 609, "chemical_mass": 70291.0, "gene_names": "Ir10a;10a;CG12623;CG12624;CG34143;DmelIR10a;Dmel\\CG34143;Dmel_CG34143;IR10a;Ir10a", "protein_name": "", "disease": [], "biological_process": [ { "name": "detection of chemical stimulus", "id": "GO:0009593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009593", "evidence": [ { "database": "UniProtKB", "id": "A8JUR3", "url": "https://www.uniprot.org/uniprotkb/A8JUR3" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A8JUR3", "url": "https://www.uniprot.org/uniprotkb/A8JUR3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A8JUR3", "url": "https://www.uniprot.org/uniprotkb/A8JUR3" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "A8JUR3", "url": "https://www.uniprot.org/uniprotkb/A8JUR3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8JUR3-1" }, { "uniprot_canonical_ac": "A8JUS8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JUS8", "url": "https://www.uniprot.org/uniprotkb/A8JUS8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 177, "chemical_mass": 20233.0, "gene_names": "Dmel\\CG13373;CG13373;Dmel\\CG13373;Dmel_CG13373", "protein_name": "Apoptosis regulatory protein Siva", "disease": [], "biological_process": [ { "name": "extrinsic apoptotic signaling pathway", "id": "GO:0097191", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097191", "evidence": [ { "database": "UniProtKB", "id": "A8JUS8", "url": "https://www.uniprot.org/uniprotkb/A8JUS8" } ], "pmid": "" } ], "molecular_function": [ { "name": "CD27 receptor binding", "id": "GO:0005175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005175", "evidence": [ { "database": "UniProtKB", "id": "A8JUS8", "url": "https://www.uniprot.org/uniprotkb/A8JUS8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8JUS8-1" }, { "uniprot_canonical_ac": "B7YZH0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7YZH0", "url": "https://www.uniprot.org/uniprotkb/B7YZH0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 145, "chemical_mass": 16296.0, "gene_names": "CG13353;CG13353;CG42287;Dmel\\CG42287;Dmel_CG42287", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "B7YZH0-1" }, { "uniprot_canonical_ac": "B7YZL9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7YZL9", "url": "https://www.uniprot.org/uniprotkb/B7YZL9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1500, "chemical_mass": 166756.0, "gene_names": "Fak;CG10023;CT28129;DFAK;DFak56;DFak;Dfak56;Dfak;DmFAK;Dmel\\CG10023;Dmel_CG10023;FAK65D;FAK;Fak56D;Fak56;Fak;dFak;fak56D;fak56;fak;pFAK;ptk2", "protein_name": "", "disease": [ { "disease_id": "DOID:0060074", "name": "ductal carcinoma in situ", "description": "A breast carcinoma in situ that is characterized by being non-invasive, not having spread outside of the duct into the surrounding breast tissue, has_material_basis_in abnormally proliferating cells, derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:0060074", "evidence": [ { "id": "0060074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060074" } ], "weight": 0.0 }, { "disease_id": "DOID:0080365", "name": "endometrial hyperplasia", "description": "An uterine benign neoplasm that is characterized by excessive proliferation of the cells of the endometrium.", "url": "https://disease-ontology.org/term/DOID:0080365", "evidence": [ { "id": "0080365", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080365" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10952", "name": "nephritis", "description": "A kidney disease that is characterized by an inflammation of the kidneys.", "url": "https://disease-ontology.org/term/DOID:10952", "evidence": [ { "id": "10952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10952" } ], "weight": 0.0 }, { "disease_id": "DOID:11713", "name": "diabetic angiopathy", "description": "A peripheral vascular disease that is characterized by narrowing of the arteries as a complication arising from chronic diabetes.", "url": "https://disease-ontology.org/term/DOID:11713", "evidence": [ { "id": "11713", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11713" } ], "weight": 0.0 }, { "disease_id": "DOID:127", "name": "leiomyoma", "description": "A cell type benign neoplasm that is a benign tumor of smooth muscle cells.", "url": "https://disease-ontology.org/term/DOID:127", "evidence": [ { "id": "127", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:127" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1824", "name": "status epilepticus", "description": "", "url": "https://disease-ontology.org/term/DOID:1824", "evidence": [ { "id": "1824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1824" } ], "weight": 0.0 }, { "disease_id": "DOID:2316", "name": "brain ischemia", "description": "An ischemia that is characterized by insufficient blood flow to the brain to meet metabolic demand.", "url": "https://disease-ontology.org/term/DOID:2316", "evidence": [ { "id": "2316", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2316" } ], "weight": 0.0 }, { "disease_id": "DOID:2871", "name": "endometrial carcinoma", "description": "A endometrial cancer that is located_in the tissue lining the uterus.", "url": "https://disease-ontology.org/term/DOID:2871", "evidence": [ { "id": "2871", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2871" } ], "weight": 0.0 }, { "disease_id": "DOID:289", "name": "endometriosis", "description": "A female reproductive system disease characterized by the growth of endometrial tissue outside the uterine body.", "url": "https://disease-ontology.org/term/DOID:289", "evidence": [ { "id": "289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:289" } ], "weight": 0.0 }, { "disease_id": "DOID:2893", "name": "cervix carcinoma", "description": "A cervical cancer that is located_in the cervix uteri or located_in the cervical area and that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:2893", "evidence": [ { "id": "2893", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2893" } ], "weight": 0.0 }, { "disease_id": "DOID:2921", "name": "glomerulonephritis", "description": "A nephritis that causes inflammation of the glomeruli located_in kidney.", "url": "https://disease-ontology.org/term/DOID:2921", "evidence": [ { "id": "2921", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2921" } ], "weight": 0.0 }, { "disease_id": "DOID:326", "name": "ischemia", "description": "A vascular disease that is characterized by a restriction in blood supply to tissues.", "url": "https://disease-ontology.org/term/DOID:326", "evidence": [ { "id": "326", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:326" } ], "weight": 0.0 }, { "disease_id": "DOID:3907", "name": "lung squamous cell carcinoma", "description": "A non-small cell lung carcinoma that has_material_basis_in the squamous cell.", "url": "https://disease-ontology.org/term/DOID:3907", "evidence": [ { "id": "3907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3907" } ], "weight": 0.0 }, { "disease_id": "DOID:4001", "name": "ovarian carcinoma", "description": "An ovarian cancer that has_material_basis_in epithelial tissue and is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:4001", "evidence": [ { "id": "4001", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4001" } ], "weight": 0.0 }, { "disease_id": "DOID:4362", "name": "cervical cancer", "description": "A female reproductive organ cancer that is located_in the cervix.", "url": "https://disease-ontology.org/term/DOID:4362", "evidence": [ { "id": "4362", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4362" } ], "weight": 0.0 }, { "disease_id": "DOID:4676", "name": "uremia", "description": "", "url": "https://disease-ontology.org/term/DOID:4676", "evidence": [ { "id": "4676", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4676" } ], "weight": 0.0 }, { "disease_id": "DOID:4780", "name": "anti-basement membrane glomerulonephritis", "description": "A Goodpasture syndrome that is characterized by damage to only kidney capillaries.", "url": "https://disease-ontology.org/term/DOID:4780", "evidence": [ { "id": "4780", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4780" } ], "weight": 0.0 }, { "disease_id": "DOID:5409", "name": "lung small cell carcinoma", "description": "A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells and is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:5409", "evidence": [ { "id": "5409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5409" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "non-membrane spanning protein tyrosine kinase activity", "id": "GO:0004715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004715", "evidence": [ { "database": "UniProtKB", "id": "B7YZL9", "url": "https://www.uniprot.org/uniprotkb/B7YZL9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "B7YZL9", "url": "https://www.uniprot.org/uniprotkb/B7YZL9" } ], "pmid": "" }, { "name": "protein tyrosine kinase activity", "id": "GO:0004713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004713", "evidence": [ { "database": "UniProtKB", "id": "B7YZL9", "url": "https://www.uniprot.org/uniprotkb/B7YZL9" } ], "pmid": "" } ], "cellular_component": [ { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "B7YZL9", "url": "https://www.uniprot.org/uniprotkb/B7YZL9" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "B7YZL9", "url": "https://www.uniprot.org/uniprotkb/B7YZL9" } ], "pmid": "" }, { "name": "type Ib terminal bouton", "id": "GO:0061176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061176", "evidence": [ { "database": "UniProtKB", "id": "B7YZL9", "url": "https://www.uniprot.org/uniprotkb/B7YZL9" } ], "pmid": "" }, { "name": "type Is terminal bouton", "id": "GO:0061177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061177", "evidence": [ { "database": "UniProtKB", "id": "B7YZL9", "url": "https://www.uniprot.org/uniprotkb/B7YZL9" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "B7YZL9", "url": "https://www.uniprot.org/uniprotkb/B7YZL9" } ], "pmid": "" }, { "name": "animal organ morphogenesis", "id": "GO:0009887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887", "evidence": [ { "database": "UniProtKB", "id": "B7YZL9", "url": "https://www.uniprot.org/uniprotkb/B7YZL9" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "B7YZL9", "url": "https://www.uniprot.org/uniprotkb/B7YZL9" } ], "pmid": "" }, { "name": "negative regulation of receptor recycling", "id": "GO:0001920", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001920", "evidence": [ { "database": "UniProtKB", "id": "B7YZL9", "url": "https://www.uniprot.org/uniprotkb/B7YZL9" } ], "pmid": "" }, { "name": "signal complex assembly", "id": "GO:0007172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007172", "evidence": [ { "database": "UniProtKB", "id": "B7YZL9", "url": "https://www.uniprot.org/uniprotkb/B7YZL9" } ], "pmid": "" }, { "name": "negative regulation of synaptic assembly at neuromuscular junction", "id": "GO:0045886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045886", "evidence": [ { "database": "UniProtKB", "id": "B7YZL9", "url": "https://www.uniprot.org/uniprotkb/B7YZL9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "B7YZL9-1" }, { "uniprot_canonical_ac": "B7YZM8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7YZM8", "url": "https://www.uniprot.org/uniprotkb/B7YZM8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 957, "chemical_mass": 108178.0, "gene_names": "BBS9;BBS9;BcDNA:RH67628;CG15666;Dmel\\CG15666;Dmel_CG15666", "protein_name": "", "disease": [ { "disease_id": "DOID:0110131", "name": "Bardet-Biedl syndrome 9", "description": "A Bardet-Biedl syndrome that has_material_basis_in homozygosity or compound heterozygosity for mutations in the PTHB1 gene on chromosome 7p14.", "url": "https://disease-ontology.org/term/DOID:0110131", "evidence": [ { "id": "0110131", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110131" } ], "weight": 0.0 }, { "disease_id": "DOID:1935", "name": "Bardet-Biedl syndrome", "description": "A syndrome that results from mutations in multiple BBS genes affecting cellular cilia structure or function (ciliopathy) resulting in variable presentation and characterized principally by obesity, retinitis pigmentosa,vision loss, polydactyly, mental retardation, hypogonadism, and renal failure in some cases.", "url": "https://disease-ontology.org/term/DOID:1935", "evidence": [ { "id": "1935", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1935" } ], "weight": 0.0 }, { "disease_id": "DOID:2340", "name": "craniosynostosis", "description": "A synostosis that results_in premature fusion located_in skull.", "url": "https://disease-ontology.org/term/DOID:2340", "evidence": [ { "id": "2340", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2340" } ], "weight": 0.0 }, { "disease_id": "DOID:5426", "name": "primary ovarian insufficiency", "description": "An ovarian disease where ovaries do not produce estrogen despite high levels of circulating gonadotropins in women under 40.", "url": "https://disease-ontology.org/term/DOID:5426", "evidence": [ { "id": "5426", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5426" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "B7YZM8", "url": "https://www.uniprot.org/uniprotkb/B7YZM8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "B7YZM8", "url": "https://www.uniprot.org/uniprotkb/B7YZM8" } ], "pmid": "" }, { "name": "BBSome", "id": "GO:0034464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034464", "evidence": [ { "database": "UniProtKB", "id": "B7YZM8", "url": "https://www.uniprot.org/uniprotkb/B7YZM8" } ], "pmid": "" } ], "biological_process": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "B7YZM8", "url": "https://www.uniprot.org/uniprotkb/B7YZM8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "B7YZM8-1" }, { "uniprot_canonical_ac": "B7YZN3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7YZN3", "url": "https://www.uniprot.org/uniprotkb/B7YZN3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 202, "chemical_mass": 23493.0, "gene_names": "Dmel\\CG42364;CG15675;CG42364;Dmel\\CG42364;Dmel_CG42364", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "B7YZN3-1" }, { "uniprot_canonical_ac": "B7YZQ6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7YZQ6", "url": "https://www.uniprot.org/uniprotkb/B7YZQ6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 574, "chemical_mass": 66287.0, "gene_names": "Ir60d;60d;CG13582;CG42291;DmelIR60d;Dmel\\CG42291;Dmel_CG42291;IR60d;Ir60d", "protein_name": "", "disease": [], "biological_process": [ { "name": "detection of chemical stimulus", "id": "GO:0009593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009593", "evidence": [ { "database": "UniProtKB", "id": "B7YZQ6", "url": "https://www.uniprot.org/uniprotkb/B7YZQ6" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "B7YZQ6", "url": "https://www.uniprot.org/uniprotkb/B7YZQ6" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "B7YZQ6", "url": "https://www.uniprot.org/uniprotkb/B7YZQ6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "B7YZQ6-1" }, { "uniprot_canonical_ac": "B7YZU6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7YZU6", "url": "https://www.uniprot.org/uniprotkb/B7YZU6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 109, "chemical_mass": 13240.0, "gene_names": "halo;CG7428;Dmel\\CG7428;Dmel_CG7428;halo", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B7YZU6", "url": "https://www.uniprot.org/uniprotkb/B7YZU6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B7YZU6", "url": "https://www.uniprot.org/uniprotkb/B7YZU6" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "B7YZU6", "url": "https://www.uniprot.org/uniprotkb/B7YZU6" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "B7YZU6", "url": "https://www.uniprot.org/uniprotkb/B7YZU6" } ], "pmid": "" }, { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "B7YZU6", "url": "https://www.uniprot.org/uniprotkb/B7YZU6" } ], "pmid": "" }, { "name": "lipid droplet transport along microtubule", "id": "GO:0031887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031887", "evidence": [ { "database": "UniProtKB", "id": "B7YZU6", "url": "https://www.uniprot.org/uniprotkb/B7YZU6" } ], "pmid": "" } ], "molecular_function": [ { "name": "kinesin binding", "id": "GO:0019894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019894", "evidence": [ { "database": "UniProtKB", "id": "B7YZU6", "url": "https://www.uniprot.org/uniprotkb/B7YZU6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "B7YZU6-1" }, { "uniprot_canonical_ac": "B7Z0E0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7Z0E0", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 479, "chemical_mass": 53643.0, "gene_names": "Idh;CG7176;CT22171;Dmel\\CG7176;Dmel_CG7176;ICDH;IDH (CG7176);IDH-NADP;IDH1;IDH2;IDH;Idh-NADP;Idh;cIdh;dIDH2;idh;isocitrate dehydrogenase;l(3)L3852", "protein_name": "Isocitrate dehydrogenase [NADP]", "disease": [ { "disease_id": "DOID:0050575", "name": "D-2-hydroxyglutaric aciduria", "description": "An 2-hydroxyglutaric aciduria that involves developmental delay, seizures, weak muscle tone (hypotonia), and abnormalities in the largest part of the brain (the cerebrum), which controls many important functions such as muscle movement, speech, vision, thinking, emotion, and memory.", "url": "https://disease-ontology.org/term/DOID:0050575", "evidence": [ { "id": "0050575", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050575" } ], "weight": 0.0 }, { "disease_id": "DOID:0050908", "name": "myelodysplastic syndrome", "description": "A bone marrow cancer that is characterized by under production of white blood cells, red blood cells and platelets.", "url": "https://disease-ontology.org/term/DOID:0050908", "evidence": [ { "id": "0050908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050908" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:3068", "name": "glioblastoma", "description": "A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.", "url": "https://disease-ontology.org/term/DOID:3068", "evidence": [ { "id": "3068", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3068" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 }, { "disease_id": "DOID:3907", "name": "lung squamous cell carcinoma", "description": "A non-small cell lung carcinoma that has_material_basis_in the squamous cell.", "url": "https://disease-ontology.org/term/DOID:3907", "evidence": [ { "id": "3907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3907" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:417", "name": "autoimmune disease", "description": "An immune system disease that is an overactive immune response of the body against substances and tissues normally present in the body resulting from an abnormal functioning of the immune system that results in the production of antibodies or T cell directed against the host tissues.", "url": "https://disease-ontology.org/term/DOID:417", "evidence": [ { "id": "417", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:417" } ], "weight": 0.0 }, { "disease_id": "DOID:5016", "name": "hepatocellular clear cell carcinoma", "description": "", "url": "https://disease-ontology.org/term/DOID:5016", "evidence": [ { "id": "5016", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5016" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 } ], "biological_process": [ { "name": "NADP+ metabolic process", "id": "GO:0006739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006739", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E0", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ], "pmid": "" }, { "name": "tricarboxylic acid cycle", "id": "GO:0006099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006099", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E0", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ], "pmid": "" }, { "name": "isocitrate metabolic process", "id": "GO:0006102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006102", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E0", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ], "pmid": "" }, { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E0", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ], "pmid": "" }, { "name": "glyoxylate cycle", "id": "GO:0006097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006097", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E0", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ], "pmid": "" } ], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E0", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ], "pmid": "" }, { "name": "NAD binding", "id": "GO:0051287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051287", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E0", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ], "pmid": "" }, { "name": "isocitrate dehydrogenase (NADP+) activity", "id": "GO:0004450", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004450", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E0", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E0", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E0", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E0", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E0", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "B7Z0E0-1" }, { "uniprot_canonical_ac": "B7Z0E3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7Z0E3", "url": "https://www.uniprot.org/uniprotkb/B7Z0E3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 323, "chemical_mass": 37840.0, "gene_names": "CT32600;Dmel\\CG13305;BcDNA:RE33542;CG13305;CT32600;Dmel\\CG13305;Dmel_CG13305", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "B7Z0E3-1" }, { "uniprot_canonical_ac": "B7Z0K3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7Z0K3", "url": "https://www.uniprot.org/uniprotkb/B7Z0K3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 455, "chemical_mass": 51193.0, "gene_names": "Dmel\\CG14866;CG14866;Dmel\\CG14866;Dmel_CG14866", "protein_name": "C-type lectin domain-containing protein", "disease": [ { "disease_id": "DOID:0050598", "name": "extrapulmonary tuberculosis", "description": "A tuberculosis that occurs at body sites other than the lung.", "url": "https://disease-ontology.org/term/DOID:0050598", "evidence": [ { "id": "0050598", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050598" } ], "weight": 0.0 }, { "disease_id": "DOID:0050827", "name": "rheumatic heart disease", "description": "A heart valve disease that is characterized by repeated inflammation with fibrinous repair caused by an autoimmune reaction to Group A beta-hemolytic streptococci (GAS) that results in valvular damage. The cardinal anatomic changes of the valve include leaflet thickening, commissural fusion, and shortening and thickening of the tendinous cords.", "url": "https://disease-ontology.org/term/DOID:0050827", "evidence": [ { "id": "0050827", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050827" } ], "weight": 0.0 }, { "disease_id": "DOID:0080599", "name": "Coronavirus infectious disease", "description": "A viral infectious disease that has_material_basis_in Coronavirus.", "url": "https://disease-ontology.org/term/DOID:0080599", "evidence": [ { "id": "0080599", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080599" } ], "weight": 0.0 }, { "disease_id": "DOID:11650", "name": "bronchopulmonary dysplasia", "description": "A lung disease that is characterized by underdeveloped lungs in newborns that can be easily irritated or inflamed after birth resulting in damage to the alveoli of the lungs and bronchi. Most newborns who develop BPD are born more than 10 weeks before their due dates, weigh less than 2 pounds at birth, and have breathing problems.", "url": "https://disease-ontology.org/term/DOID:11650", "evidence": [ { "id": "11650", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11650" } ], "weight": 0.0 }, { "disease_id": "DOID:12205", "name": "dengue disease", "description": "A viral infectious disease that results in infection, has_material_basis_in Dengue virus (Orthoflavivirus denguei), which are transmitted by Aedes mosquito bite. The infection has symptom fever, has symptom severe headache, has symptom severe pain behind the eyes, has symptom joint pain, has symptom muscle and bone pain, has symptom rash, and has symptom mild bleeding.", "url": "https://disease-ontology.org/term/DOID:12205", "evidence": [ { "id": "12205", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12205" } ], "weight": 0.0 }, { "disease_id": "DOID:12206", "name": "dengue hemorrhagic fever", "description": "A dengue disease that occurs when a person experiences a second infection with a heterologous Dengue virus (Orthoflavivirus denguei) serotype, which is transmitted_by Aedes mosquito bite. The infection has_symptom hemorrhagic lesions of the skin, has_symptom thrombocytopenia, has_symptom reduction in the fluid part of the blood, and has_symptom high fever. Four distinct Dengue virus serotypes have been identified.", "url": "https://disease-ontology.org/term/DOID:12206", "evidence": [ { "id": "12206", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12206" } ], "weight": 0.0 }, { "disease_id": "DOID:13564", "name": "aspergillosis", "description": "An opportunistic mycosis that involves a spectrum of diseases of humans and animals caused by members of the genus Aspergillus infecting lungs, brain, kidney, heart, bone, eyes, sinuses, skin and gastrointestinal tract. It is a serious illnesses in people with a weakened immune system.", "url": "https://disease-ontology.org/term/DOID:13564", "evidence": [ { "id": "13564", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13564" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:2957", "name": "pulmonary tuberculosis", "description": "A tuberculosis that is a contagious disease located_in lungs. The infection has_symptom fever, has_symptom cough, has_symptom difficulty in breathing, has_symptom inflammatory infiltrations, has_symptom formation of tubercles, has_symptom caseation, has_symptom pleural effusion, and has_symptom fibrosis.", "url": "https://disease-ontology.org/term/DOID:2957", "evidence": [ { "id": "2957", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2957" } ], "weight": 0.0 }, { "disease_id": "DOID:399", "name": "tuberculosis", "description": "A primary bacterial infectious disease that is located_in lungs, located_in lymph nodes, located_in pericardium, located_in brain, located_in pleura or located_in gastrointestinal tract, has_material_basis_in Mycobacterium tuberculosis, which is transmitted_by droplets released into the air when an infected person coughs or sneezes.", "url": "https://disease-ontology.org/term/DOID:399", "evidence": [ { "id": "399", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:399" } ], "weight": 0.0 }, { "disease_id": "DOID:526", "name": "human immunodeficiency virus infectious disease", "description": "A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.", "url": "https://disease-ontology.org/term/DOID:526", "evidence": [ { "id": "526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:526" } ], "weight": 0.0 }, { "disease_id": "DOID:635", "name": "acquired immunodeficiency syndrome", "description": "A Human immunodeficiency virus infectious disease that results_in reduction in the numbers of CD4-bearing helper T cells below 200 per microliter of blood or 14% of all lymphocytes thereby rendering the subject highly vulnerable to life-threatening infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted_by sexual contact, transmitted_by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted_by congenital method, and transmitted_by contaminated needles. Opportunistic infections are common in people with AIDS.", "url": "https://disease-ontology.org/term/DOID:635", "evidence": [ { "id": "635", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:635" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 } ], "biological_process": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "B7Z0K3", "url": "https://www.uniprot.org/uniprotkb/B7Z0K3" } ], "pmid": "" } ], "cellular_component": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "B7Z0K3", "url": "https://www.uniprot.org/uniprotkb/B7Z0K3" } ], "pmid": "" } ], "molecular_function": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "B7Z0K3", "url": "https://www.uniprot.org/uniprotkb/B7Z0K3" } ], "pmid": "" }, { "name": "pattern recognition receptor activity", "id": "GO:0038187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038187", "evidence": [ { "database": "UniProtKB", "id": "B7Z0K3", "url": "https://www.uniprot.org/uniprotkb/B7Z0K3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "B7Z0K3-1" }, { "uniprot_canonical_ac": "B7Z0L3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7Z0L3", "url": "https://www.uniprot.org/uniprotkb/B7Z0L3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 282, "chemical_mass": 31019.0, "gene_names": "CG5240;CG31266;CG5240;Dmel\\CG31266;Dmel_CG31266;SPH146a;SPH146", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "molecular_function": [ { "name": "endopeptidase activity", "id": "GO:0004175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004175", "evidence": [ { "database": "UniProtKB", "id": "B7Z0L3", "url": "https://www.uniprot.org/uniprotkb/B7Z0L3" } ], "pmid": "" }, { "name": "serine-type peptidase activity", "id": "GO:0008236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008236", "evidence": [ { "database": "UniProtKB", "id": "B7Z0L3", "url": "https://www.uniprot.org/uniprotkb/B7Z0L3" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "B7Z0L3", "url": "https://www.uniprot.org/uniprotkb/B7Z0L3" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "B7Z0L3", "url": "https://www.uniprot.org/uniprotkb/B7Z0L3" } ], "pmid": "" }, { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "B7Z0L3", "url": "https://www.uniprot.org/uniprotkb/B7Z0L3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "B7Z0L3-1" }, { "uniprot_canonical_ac": "B7Z0S9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7Z0S9", "url": "https://www.uniprot.org/uniprotkb/B7Z0S9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 243, "chemical_mass": 27841.0, "gene_names": "GstD11;BcDNA:RE72392;CG17639;DmGSTD11;Dmel\\CG17639;Dmel_CG17639;GSTD11;GstD11;cg17639;gstd11", "protein_name": "", "disease": [], "molecular_function": [ { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "B7Z0S9", "url": "https://www.uniprot.org/uniprotkb/B7Z0S9" } ], "pmid": "" }, { "name": "glutathione peroxidase activity", "id": "GO:0004602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004602", "evidence": [ { "database": "UniProtKB", "id": "B7Z0S9", "url": "https://www.uniprot.org/uniprotkb/B7Z0S9" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B7Z0S9", "url": "https://www.uniprot.org/uniprotkb/B7Z0S9" } ], "pmid": "" } ], "biological_process": [ { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "B7Z0S9", "url": "https://www.uniprot.org/uniprotkb/B7Z0S9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "B7Z0S9-1" }, { "uniprot_canonical_ac": "B7Z0X5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7Z0X5", "url": "https://www.uniprot.org/uniprotkb/B7Z0X5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 608, "chemical_mass": 71243.0, "gene_names": "Ir7e;7e;CG15327;CG42293;DmelIR7e;Dmel\\CG42293;Dmel_CG42293;IR7e;Ir7e", "protein_name": "", "disease": [], "biological_process": [ { "name": "detection of chemical stimulus", "id": "GO:0009593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009593", "evidence": [ { "database": "UniProtKB", "id": "B7Z0X5", "url": "https://www.uniprot.org/uniprotkb/B7Z0X5" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "B7Z0X5", "url": "https://www.uniprot.org/uniprotkb/B7Z0X5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "B7Z0X5", "url": "https://www.uniprot.org/uniprotkb/B7Z0X5" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "B7Z0X5", "url": "https://www.uniprot.org/uniprotkb/B7Z0X5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "B7Z0X5-1" }, { "uniprot_canonical_ac": "E1JH12-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JH12", "url": "https://www.uniprot.org/uniprotkb/E1JH12" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 67, "chemical_mass": 7996.0, "gene_names": "Dmel\\CG42615;CG42615;Dmel\\CG42615;Dmel_CG42615;gft", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "E1JH12-1" }, { "uniprot_canonical_ac": "E1JHF6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JHF6", "url": "https://www.uniprot.org/uniprotkb/E1JHF6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 91, "chemical_mass": 10709.0, "gene_names": "Dmel\\CG42470;CG42470;Dmel\\CG42470;Dmel_CG42470", "protein_name": "Seminal fluid protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "E1JHF6-1" }, { "uniprot_canonical_ac": "E1JHF9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JHF9", "url": "https://www.uniprot.org/uniprotkb/E1JHF9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 215, "chemical_mass": 24011.0, "gene_names": "Dmel\\CG14932;CG14932;Dmel\\CG14932;Dmel_CG14932", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "E1JHF9-1", "start_pos": "149", "end_pos": "149", "site_lbl": "Thr149", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 149, "start_aa": "Thr", "end_pos": 149, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr149", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "E1JHF9-1" }, { "uniprot_canonical_ac": "E1JHS7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JHS7", "url": "https://www.uniprot.org/uniprotkb/E1JHS7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 82, "chemical_mass": 9623.0, "gene_names": "Dmel\\CG42467;CG42467;Dmel\\CG42467;Dmel_CG42467", "protein_name": "Seminal fluid protein", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "E1JHS7", "url": "https://www.uniprot.org/uniprotkb/E1JHS7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "E1JHS7-1" }, { "uniprot_canonical_ac": "E1JHT4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JHT4", "url": "https://www.uniprot.org/uniprotkb/E1JHT4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 496, "chemical_mass": 54978.0, "gene_names": "Dmel\\CG12194;anon-EST:Posey105;CG12194;Dmel\\CG12194;Dmel_CG12194;anon-EST:Posey105", "protein_name": "Lysosomal dipeptide transporter MFSD1", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1JHT4", "url": "https://www.uniprot.org/uniprotkb/E1JHT4" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "E1JHT4", "url": "https://www.uniprot.org/uniprotkb/E1JHT4" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "E1JHT4", "url": "https://www.uniprot.org/uniprotkb/E1JHT4" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "E1JHT4", "url": "https://www.uniprot.org/uniprotkb/E1JHT4" } ], "pmid": "" } ], "biological_process": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "E1JHT4", "url": "https://www.uniprot.org/uniprotkb/E1JHT4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "E1JHT4-1" }, { "uniprot_canonical_ac": "E1JJ15-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JJ15", "url": "https://www.uniprot.org/uniprotkb/E1JJ15" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 142, "chemical_mass": 15720.0, "gene_names": "Dmel\\CG42592;CG42592;Dmel\\CG42592;Dmel_CG42592", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "E1JJ15-1" }, { "uniprot_canonical_ac": "E1JJ89-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JJ89", "url": "https://www.uniprot.org/uniprotkb/E1JJ89" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 559, "chemical_mass": 62597.0, "gene_names": "CT41336;CG18249;CT41336;Dmel\\CG18249;Dmel_CG18249", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "E1JJ89-1", "start_pos": "52", "end_pos": "52", "site_lbl": "Thr52", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 52, "start_aa": "Thr", "end_pos": 52, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr52", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "E1JJ89-1" }, { "uniprot_canonical_ac": "E1JJS0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JJS0", "url": "https://www.uniprot.org/uniprotkb/E1JJS0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 92, "chemical_mass": 10654.0, "gene_names": "Dmel\\CG42578;CG42578;Dmel\\CG42578;Dmel_CG42578", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "E1JJS0-1" }, { "uniprot_canonical_ac": "E2QCN8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E2QCN8", "url": "https://www.uniprot.org/uniprotkb/E2QCN8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 123, "chemical_mass": 13519.0, "gene_names": "Dmel\\CG15870;CG15870;Dmel\\CG15870;Dmel_CG15870", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "E2QCN8-1" }, { "uniprot_canonical_ac": "E2QCZ5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E2QCZ5", "url": "https://www.uniprot.org/uniprotkb/E2QCZ5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 726, "chemical_mass": 82361.0, "gene_names": "Dmel\\CG7706;CG7706;Dmel\\CG7706;Dmel_CG7706", "protein_name": "FHA domain-containing protein", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "E2QCZ5", "url": "https://www.uniprot.org/uniprotkb/E2QCZ5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "E2QCZ5-1" }, { "uniprot_canonical_ac": "E2QD54-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E2QD54", "url": "https://www.uniprot.org/uniprotkb/E2QD54" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 553, "chemical_mass": 62389.0, "gene_names": "natalisin;CG14842;CG14843;CG34388;Dmel\\CG34388;Dmel_CG34388;NTL;Ntl;natalisin;ntl", "protein_name": "", "disease": [], "biological_process": [ { "name": "male mating behavior", "id": "GO:0060179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060179", "evidence": [ { "database": "UniProtKB", "id": "E2QD54", "url": "https://www.uniprot.org/uniprotkb/E2QD54" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E2QD54", "url": "https://www.uniprot.org/uniprotkb/E2QD54" } ], "pmid": "" } ], "molecular_function": [ { "name": "neuropeptide activity", "id": "GO:0160041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160041", "evidence": [ { "database": "UniProtKB", "id": "E2QD54", "url": "https://www.uniprot.org/uniprotkb/E2QD54" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "E2QD54-1" }, { "uniprot_canonical_ac": "M9MRH9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9MRH9", "url": "https://www.uniprot.org/uniprotkb/M9MRH9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 186, "chemical_mass": 20706.0, "gene_names": "Dmel\\CG42711;CG42711;Dmel\\CG42711;Dmel_CG42711", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9MRH9-1" }, { "uniprot_canonical_ac": "M9MRN0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9MRN0", "url": "https://www.uniprot.org/uniprotkb/M9MRN0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 145, "chemical_mass": 15630.0, "gene_names": "Dmel\\CG42809;CG16849;CG42809;Dmel\\CG42809;Dmel_CG42809", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9MRN0-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Thr53", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 53, "start_aa": "Thr", "end_pos": 53, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr53", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9MRN0-1" }, { "uniprot_canonical_ac": "M9MRN7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9MRN7", "url": "https://www.uniprot.org/uniprotkb/M9MRN7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 167, "chemical_mass": 17879.0, "gene_names": "Dmel\\CG42846;CG42846;Dmel\\CG42846;Dmel_CG42846", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9MRN7-1" }, { "uniprot_canonical_ac": "M9MRP4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9MRP4", "url": "https://www.uniprot.org/uniprotkb/M9MRP4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 494, "chemical_mass": 56638.0, "gene_names": "Dmel\\CG13924;CG13924;Dmel\\CG13924;Dmel_CG13924", "protein_name": "Coiled-coil domain-containing protein 181", "disease": [], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "M9MRP4", "url": "https://www.uniprot.org/uniprotkb/M9MRP4" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "M9MRP4", "url": "https://www.uniprot.org/uniprotkb/M9MRP4" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "M9MRP4", "url": "https://www.uniprot.org/uniprotkb/M9MRP4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9MRP4-1", "start_pos": "330", "end_pos": "330", "site_lbl": "Thr330", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 330, "start_aa": "Thr", "end_pos": 330, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr330", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9MRP4-1" }, { "uniprot_canonical_ac": "M9MRQ3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9MRQ3", "url": "https://www.uniprot.org/uniprotkb/M9MRQ3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 49, "chemical_mass": 5700.0, "gene_names": "Dmel\\CG42659;CG42659;Dmel\\CG42659;Dmel_CG42659;noncoding_3557", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9MRQ3-1" }, { "uniprot_canonical_ac": "M9MRV6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9MRV6", "url": "https://www.uniprot.org/uniprotkb/M9MRV6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 79, "chemical_mass": 8820.0, "gene_names": "Dmel\\CG42718;CG42718;Dmel\\CG42718;Dmel_CG42718", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9MRV6-1" }, { "uniprot_canonical_ac": "M9MS52-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9MS52", "url": "https://www.uniprot.org/uniprotkb/M9MS52" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 32, "chemical_mass": 3149.0, "gene_names": "Dmel\\CG42852;CG42852;Dmel\\CG42852;Dmel_CG42852;lincRNA.585", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9MS52-1" }, { "uniprot_canonical_ac": "M9NCQ5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NCQ5", "url": "https://www.uniprot.org/uniprotkb/M9NCQ5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 42, "chemical_mass": 4719.0, "gene_names": "Dmel\\CG43403;CG43403;Dmel\\CG43403;Dmel_CG43403", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9NCQ5-1" }, { "uniprot_canonical_ac": "M9ND23-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9ND23", "url": "https://www.uniprot.org/uniprotkb/M9ND23" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 82, "chemical_mass": 9257.0, "gene_names": "Dmel\\CG43056;CG43056;Dmel\\CG43056;Dmel_CG43056", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9ND23-1" }, { "uniprot_canonical_ac": "M9NDP8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NDP8", "url": "https://www.uniprot.org/uniprotkb/M9NDP8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 143, "chemical_mass": 16666.0, "gene_names": "Dmel\\CG43294;CG43294;Dmel\\CG43294;Dmel_CG43294", "protein_name": "Chitin-binding type-2 domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "M9NDP8", "url": "https://www.uniprot.org/uniprotkb/M9NDP8" } ], "pmid": "" } ], "molecular_function": [ { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "M9NDP8", "url": "https://www.uniprot.org/uniprotkb/M9NDP8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9NDP8-1" }, { "uniprot_canonical_ac": "M9NDQ6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NDQ6", "url": "https://www.uniprot.org/uniprotkb/M9NDQ6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 81, "chemical_mass": 9204.0, "gene_names": "chr3L_13830834_13831226.0;CG43184;Dmel\\CG43184;Dmel_CG43184;FBgn0262813;chr3L_13830834_13831226.0", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9NDQ6-1" }, { "uniprot_canonical_ac": "M9NDU9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NDU9", "url": "https://www.uniprot.org/uniprotkb/M9NDU9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 70, "chemical_mass": 8203.0, "gene_names": "Dmel\\CG43156;CG43156;Dmel\\CG43156;Dmel_CG43156;lincRNA.980", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9NDU9-1" }, { "uniprot_canonical_ac": "M9NE05-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NE05", "url": "https://www.uniprot.org/uniprotkb/M9NE05" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2192, "chemical_mass": 244593.0, "gene_names": "nrm;CG32458;CG41452;CG43079;CG8779;CT16082;Dmel\\CG43079;Dmel_CG43079;nrm", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M9NE05", "url": "https://www.uniprot.org/uniprotkb/M9NE05" } ], "pmid": "" } ], "biological_process": [ { "name": "synaptic target recognition", "id": "GO:0008039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008039", "evidence": [ { "database": "UniProtKB", "id": "M9NE05", "url": "https://www.uniprot.org/uniprotkb/M9NE05" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9NE05-1", "start_pos": "1593", "end_pos": "1593", "site_lbl": "Thr1593", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1593, "start_aa": "Thr", "end_pos": 1593, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1593", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9NE05-1", "start_pos": "1814", "end_pos": "1814", "site_lbl": "Thr1814", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1814, "start_aa": "Thr", "end_pos": 1814, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1814", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9NE05-1", "start_pos": "690", "end_pos": "690", "site_lbl": "Thr690", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 690, "start_aa": "Thr", "end_pos": 690, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr690", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "M9NE05", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=M9NE05" } ] } ] }, { "uniprot_canonical_ac": "M9NE05-1", "start_pos": "692", "end_pos": "692", "site_lbl": "Thr692", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 692, "start_aa": "Thr", "end_pos": 692, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr692", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "M9NE05", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=M9NE05" } ] } ] } ], "record_id": "M9NE05-1" }, { "uniprot_canonical_ac": "M9NE75-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NE75", "url": "https://www.uniprot.org/uniprotkb/M9NE75" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 60, "chemical_mass": 7059.0, "gene_names": "lincRNA.945;CG43288;Dmel\\CG43288;Dmel_CG43288;lincRNA.945", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9NE75-1" }, { "uniprot_canonical_ac": "M9NET3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NET3", "url": "https://www.uniprot.org/uniprotkb/M9NET3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 32, "chemical_mass": 3727.0, "gene_names": "lincRNA.182;CG43354;Dmel\\CG43354;Dmel_CG43354;lincRNA.182", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9NET3-1" }, { "uniprot_canonical_ac": "M9NF24-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NF24", "url": "https://www.uniprot.org/uniprotkb/M9NF24" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 628, "chemical_mass": 65322.0, "gene_names": "Dmel\\CG43332;BG:DS01523.2;CG15291;CG32972;CG43332;Dmel\\CG43332;Dmel_CG43332", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9NF24-1" }, { "uniprot_canonical_ac": "M9NF55-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NF55", "url": "https://www.uniprot.org/uniprotkb/M9NF55" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 174, "chemical_mass": 20933.0, "gene_names": "Dmel\\CG43075;CG43075;Dmel\\CG43075;Dmel_CG43075", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9NF55-1" }, { "uniprot_canonical_ac": "M9NFG6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NFG6", "url": "https://www.uniprot.org/uniprotkb/M9NFG6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 72, "chemical_mass": 8040.0, "gene_names": "UQCR-6.4L;CG43206;Dmel\\CG43206;Dmel_CG43206;UQCR-6.4L;chr3L_16559870_16560394.0", "protein_name": "", "disease": [], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "M9NFG6", "url": "https://www.uniprot.org/uniprotkb/M9NFG6" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial electron transport, ubiquinol to cytochrome c", "id": "GO:0006122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006122", "evidence": [ { "database": "UniProtKB", "id": "M9NFG6", "url": "https://www.uniprot.org/uniprotkb/M9NFG6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9NFG6-1" }, { "uniprot_canonical_ac": "Q0KHR3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1520, "chemical_mass": 163622.0, "gene_names": "baz;BAZ;Baz/Par-3;Baz/Par3;Bazooka;Baz;CG5055;D-Par3;D-par3;Dmel\\CG5055;Dmel_CG5055;PAR-3;PAR3;Par-3;Par3;baz;dPar-3;l(1)G0484;par-3;par3", "protein_name": "", "disease": [ { "disease_id": "DOID:0060037", "name": "developmental disorder of mental health", "description": "A disease of mental health that occur during a child's developmental period between birth and age 18 resulting in retarding of the child's psychological or physical development.", "url": "https://disease-ontology.org/term/DOID:0060037", "evidence": [ { "id": "0060037", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060037" } ], "weight": 0.0 } ], "biological_process": [ { "name": "establishment of apical/basal cell polarity", "id": "GO:0035089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035089", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "synapse assembly", "id": "GO:0007416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007416", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "adherens junction organization", "id": "GO:0034332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034332", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "negative regulation of filopodium assembly", "id": "GO:0051490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051490", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "branching involved in open tracheal system development", "id": "GO:0060446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060446", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "asymmetric neuroblast division", "id": "GO:0055059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055059", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "zonula adherens assembly", "id": "GO:0045186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045186", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "photoreceptor cell morphogenesis", "id": "GO:0008594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008594", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "establishment or maintenance of epithelial cell apical/basal polarity", "id": "GO:0045197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045197", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "asymmetric protein localization involved in cell fate determination", "id": "GO:0045167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045167", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "follicle cell of egg chamber-cell adhesion", "id": "GO:0007299", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007299", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "Malpighian tubule development", "id": "GO:0072002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072002", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "germarium-derived oocyte fate determination", "id": "GO:0007294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007294", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "border follicle cell migration", "id": "GO:0007298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007298", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "oocyte anterior/posterior axis specification", "id": "GO:0007314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007314", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "germ-band extension", "id": "GO:0007377", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007377", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "oocyte microtubule cytoskeleton organization", "id": "GO:0016325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016325", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "border follicle cell delamination", "id": "GO:0030709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030709", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "positive regulation of Notch signaling pathway", "id": "GO:0045747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045747", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "establishment of cell polarity", "id": "GO:0030010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030010", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "establishment or maintenance of cell polarity", "id": "GO:0007163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007163", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "axis elongation", "id": "GO:0003401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003401", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "regulation of establishment of planar polarity", "id": "GO:0090175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090175", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "apical protein localization", "id": "GO:0045176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045176", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" } ], "cellular_component": [ { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "apical junction complex", "id": "GO:0043296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043296", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "zonula adherens", "id": "GO:0005915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005915", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "spot adherens junction", "id": "GO:0005914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005914", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "cytoplasmic side of apical plasma membrane", "id": "GO:0098592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098592", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "PAR polarity complex", "id": "GO:0120157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120157", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "phosphatidic acid binding", "id": "GO:0070300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070300", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q0KHR3-1" }, { "uniprot_canonical_ac": "Q0E9H9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2016, "chemical_mass": 222102.0, "gene_names": "Dscam1;43Bc;CG17800;CT39257;DSCAM1;DSCAM;DScam;DmDscam;Dm_2R:13579;Dm_2R:13612;Dmel\\CG17800;Dmel_CG17800;DsCam;Dscam-hv;Dscam1;Dscam;Dsm;Neu1;dScam;dscam1;dscam;l(2)05518;l(2)43Bc;p270", "protein_name": "Cell adhesion molecule Dscam1", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0080849", "name": "ocular motor apraxia, Cogan type", "description": "An eye disease that is characterized by defective or absent horizontal voluntary eye movements, and defective or absent horizontal ocular attraction movements.", "url": "https://disease-ontology.org/term/DOID:0080849", "evidence": [ { "id": "0080849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080849" } ], "weight": 0.0 }, { "disease_id": "DOID:1279", "name": "ocular motility disease", "description": "", "url": "https://disease-ontology.org/term/DOID:1279", "evidence": [ { "id": "1279", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1279" } ], "weight": 0.0 }, { "disease_id": "DOID:14250", "name": "Down syndrome", "description": "A chromosomal duplication syndrome that is characterized by flat-looking facial features and weak muscle tone (hypotonia) in infancy and is caused by trisomy of all or a critical portion of chromosome 21 and is associated with intellectual disability.", "url": "https://disease-ontology.org/term/DOID:14250", "evidence": [ { "id": "14250", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14250" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of axonogenesis", "id": "GO:0050770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050770", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "central nervous system morphogenesis", "id": "GO:0021551", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021551", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "detection of mechanical stimulus involved in sensory perception of touch", "id": "GO:0050976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050976", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "regulation of dendrite morphogenesis", "id": "GO:0048814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048814", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "phagocytosis", "id": "GO:0006909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006909", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "peripheral nervous system development", "id": "GO:0007422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007422", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "axonal fasciculation", "id": "GO:0007413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007413", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "neuron development", "id": "GO:0048666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048666", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "dendrite self-avoidance", "id": "GO:0070593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070593", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "detection of molecule of bacterial origin", "id": "GO:0032490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032490", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "axon extension involved in axon guidance", "id": "GO:0048846", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048846", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "ventral cord development", "id": "GO:0007419", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007419", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "mushroom body development", "id": "GO:0016319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016319", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "antigen binding", "id": "GO:0003823", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003823", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "axon guidance receptor activity", "id": "GO:0008046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008046", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q0E9H9-1", "start_pos": "1022", "end_pos": "1022", "site_lbl": "Asn1022", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1022, "start_aa": "Asn", "end_pos": 1022, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1022", "evidence": [ { "id": "Q0E9H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q0E9H9-1", "start_pos": "1055", "end_pos": "1055", "site_lbl": "Asn1055", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1055, "start_aa": "Asn", "end_pos": 1055, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1055", "evidence": [ { "id": "Q0E9H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q0E9H9-1", "start_pos": "1113", "end_pos": "1113", "site_lbl": "Thr1113", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1113, "start_aa": "Thr", "end_pos": 1113, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1113", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q0E9H9-1", "start_pos": "1186", "end_pos": "1186", "site_lbl": "Asn1186", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1186, "start_aa": "Asn", "end_pos": 1186, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1186", "evidence": [ { "id": "Q0E9H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q0E9H9-1", "start_pos": "1219", "end_pos": "1219", "site_lbl": "Thr1219", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1219, "start_aa": "Thr", "end_pos": 1219, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1219", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q0E9H9-1", "start_pos": "325", "end_pos": "325", "site_lbl": "Asn325", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G22768VO", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": { "label": "iCn3D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?bcifid=4X9F&bu=0&command=select+.B:291;+center+selection;+zoom+selection" }, "start_pos": 325, "start_aa": "Asn", "end_pos": 325, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn325", "evidence": [ { "id": "4X9F", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9F" }, { "id": "4X9F", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9F" }, { "id": "4X9G", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9G" }, { "id": "4X9G", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9G" }, { "id": "4XHQ", "database": "PDB", "url": "https://www.rcsb.org/structure/4XHQ" }, { "id": "4XHQ", "database": "PDB", "url": "https://www.rcsb.org/structure/4XHQ" }, { "id": "4X9F|B|291", "database": "", "url": "" }, { "id": "4X9G|B|291", "database": "", "url": "" }, { "id": "4X9G|A|291", "database": "", "url": "" }, { "id": "4XHQ|A|290", "database": "", "url": "" } ] }, { "glytoucan_ac": "G81315DD", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": { "label": "iCn3D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?bcifid=4X8X&bu=0&command=select+.B:291;+center+selection;+zoom+selection" }, "start_pos": 325, "start_aa": "Asn", "end_pos": 325, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn325", "evidence": [ { "id": "4X8X", "database": "PDB", "url": "https://www.rcsb.org/structure/4X8X" }, { "id": "4X8X", "database": "PDB", "url": "https://www.rcsb.org/structure/4X8X" }, { "id": "4X8X|B|291", "database": "", "url": "" }, { "id": "4X8X|A|291", "database": "", "url": "" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": { "label": "iCn3D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?bcifid=4X83&bu=0&command=select+.D:291;+center+selection;+zoom+selection" }, "start_pos": 325, "start_aa": "Asn", "end_pos": 325, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn325", "evidence": [ { "id": "Q0E9H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" }, { "id": "27386517", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/27386517" }, { "id": "17721508", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/17721508" }, { "id": "4XHQ", "database": "PDB", "url": "https://www.rcsb.org/sequence/4XHQ" }, { "id": "2V5M", "database": "PDB", "url": "https://www.rcsb.org/sequence/2V5M" }, { "id": "18805093", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/18805093" }, { "id": "3DMK", "database": "PDB", "url": "https://www.rcsb.org/sequence/3DMK" }, { "id": "4X83", "database": "PDB", "url": "https://www.rcsb.org/structure/4X83" }, { "id": "4X83", "database": "PDB", "url": "https://www.rcsb.org/structure/4X83" }, { "id": "4X9B", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9B" }, { "id": "4X9B", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9B" }, { "id": "4X9H", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9H" }, { "id": "4X9H", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9H" }, { "id": "4X83|D|291", "database": "", "url": "" }, { "id": "4X83|B|291", "database": "", "url": "" }, { "id": "4X83|A|291", "database": "", "url": "" }, { "id": "4X9B|A|294", "database": "", "url": "" }, { "id": "4X9B|B|294", "database": "", "url": "" }, { "id": "4X9H|B|297", "database": "", "url": "" }, { "id": "4X9H|A|297", "database": "", "url": "" } ] } ] }, { "uniprot_canonical_ac": "Q0E9H9-1", "start_pos": "457", "end_pos": "457", "site_lbl": "Thr457", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 457, "start_aa": "Thr", "end_pos": 457, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr457", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q0E9H9-1", "start_pos": "492", "end_pos": "492", "site_lbl": "Asn492", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 492, "start_aa": "Asn", "end_pos": 492, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn492", "evidence": [ { "id": "Q0E9H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9#ptm_processing" }, { "id": "18805093", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/18805093" }, { "id": "3DMK", "database": "PDB", "url": "https://www.rcsb.org/sequence/3DMK" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q0E9H9-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Asn53", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G22573RC", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": { "label": "iCn3D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?bcifid=4X8X&bu=0&command=select+.B:18;+center+selection;+zoom+selection" }, "start_pos": 53, "start_aa": "Asn", "end_pos": 53, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn53", "evidence": [ { "id": "4X8X", "database": "PDB", "url": "https://www.rcsb.org/structure/4X8X" }, { "id": "4X8X", "database": "PDB", "url": "https://www.rcsb.org/structure/4X8X" }, { "id": "4X9B", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9B" }, { "id": "4X9B", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9B" }, { "id": "4XB8", "database": "PDB", "url": "https://www.rcsb.org/structure/4XB8" }, { "id": "4XB8", "database": "PDB", "url": "https://www.rcsb.org/structure/4XB8" }, { "id": "4X8X|B|18", "database": "", "url": "" }, { "id": "4X9B|A|18", "database": "", "url": "" }, { "id": "4XB8|A|18", "database": "", "url": "" } ] }, { "glytoucan_ac": "G22768VO", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": { "label": "iCn3D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?bcifid=4X9F&bu=0&command=select+.A:18;+center+selection;+zoom+selection" }, "start_pos": 53, "start_aa": "Asn", "end_pos": 53, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn53", "evidence": [ { "id": "4X9F", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9F" }, { "id": "4X9F", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9F" }, { "id": "4X9G", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9G" }, { "id": "4X9G", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9G" }, { "id": "4X9F|A|18", "database": "", "url": "" }, { "id": "4X9G|A|18", "database": "", "url": "" } ] }, { "glytoucan_ac": "G81315DD", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": { "label": "iCn3D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?bcifid=4X8X&bu=0&command=select+.A:18;+center+selection;+zoom+selection" }, "start_pos": 53, "start_aa": "Asn", "end_pos": 53, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn53", "evidence": [ { "id": "4X8X", "database": "PDB", "url": "https://www.rcsb.org/structure/4X8X" }, { "id": "4X8X", "database": "PDB", "url": "https://www.rcsb.org/structure/4X8X" }, { "id": "4X9H", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9H" }, { "id": "4X9H", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9H" }, { "id": "4X9I", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9I" }, { "id": "4X9I", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9I" }, { "id": "4X8X|A|18", "database": "", "url": "" }, { "id": "4X9H|B|18", "database": "", "url": "" }, { "id": "4X9H|A|18", "database": "", "url": "" }, { "id": "4X9I|A|18", "database": "", "url": "" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": { "label": "iCn3D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?bcifid=4XB8&bu=0&command=select+.B:18;+center+selection;+zoom+selection" }, "start_pos": 53, "start_aa": "Asn", "end_pos": 53, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn53", "evidence": [ { "id": "Q0E9H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9#ptm_processing" }, { "id": "27386517", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/27386517" }, { "id": "17721508", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/17721508" }, { "id": "18805093", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/18805093" }, { "id": "4XHQ", "database": "PDB", "url": "https://www.rcsb.org/sequence/4XHQ" }, { "id": "2V5M", "database": "PDB", "url": "https://www.rcsb.org/sequence/2V5M" }, { "id": "2V5R", "database": "PDB", "url": "https://www.rcsb.org/sequence/2V5R" }, { "id": "3DMK", "database": "PDB", "url": "https://www.rcsb.org/sequence/3DMK" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" }, { "id": "4XB8", "database": "PDB", "url": "https://www.rcsb.org/structure/4XB8" }, { "id": "4XB8", "database": "PDB", "url": "https://www.rcsb.org/structure/4XB8" }, { "id": "4XB8|B|18", "database": "", "url": "" } ] } ] }, { "uniprot_canonical_ac": "Q0E9H9-1", "start_pos": "577", "end_pos": "577", "site_lbl": "Asn577", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 577, "start_aa": "Asn", "end_pos": 577, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn577", "evidence": [ { "id": "Q0E9H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9#ptm_processing" }, { "id": "18805093", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/18805093" }, { "id": "3DMK", "database": "PDB", "url": "https://www.rcsb.org/sequence/3DMK" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q0E9H9-1", "start_pos": "755", "end_pos": "755", "site_lbl": "Thr755", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 755, "start_aa": "Thr", "end_pos": 755, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr755", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q0E9H9-1", "start_pos": "820", "end_pos": "820", "site_lbl": "Asn820", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 820, "start_aa": "Asn", "end_pos": 820, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn820", "evidence": [ { "id": "Q0E9H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q0E9H9-1", "start_pos": "530", "end_pos": "530", "site_lbl": "Arg530", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "W", "comment": "In DscamR496W; loss of function probably due to disruption of the intramolecular binding interface between Ig-like domains 5 and 6; dorsal lobe nerve tract does not form and the medial lobe fails to extend to the midline.", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" }, { "database": "PubMed", "id": "18805093", "url": "https://glygen.org/publication/PubMed/18805093" } ] } ] } ], "record_id": "Q0E9H9-1" }, { "uniprot_canonical_ac": "Q9VB15-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VB15", "url": "https://www.uniprot.org/uniprotkb/Q9VB15" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 717, "chemical_mass": 77997.0, "gene_names": "tau;BcDNA:RE16764;CG12881;CG31057;CG31058;CG34294;CG45110;CG5606;Dmel\\CG45110;Dmel_CG45110;Tau;d-tau;dTAU;dTau;dtau;tao;tau", "protein_name": "Microtubule-associated protein", "disease": [ { "disease_id": "DOID:0050741", "name": "alcohol dependence", "description": "A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.", "url": "https://disease-ontology.org/term/DOID:0050741", "evidence": [ { "id": "0050741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050741" } ], "weight": 0.0 }, { "disease_id": "DOID:0051060", "name": "frontotemporal dementia 1", "description": "A frontotemporal dementia that has_material_basis_in heterozygous mutation in the MAPT gene, which encodes microtubule-associated protein tau, on chromosome 17q21.", "url": "https://disease-ontology.org/term/DOID:0051060", "evidence": [ { "id": "0051060", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051060" } ], "weight": 0.0 }, { "disease_id": "DOID:0060892", "name": "late onset Parkinson's disease", "description": "A Parkinson's disease characterized by onset of motor symptoms typically after 60 years of age.", "url": "https://disease-ontology.org/term/DOID:0060892", "evidence": [ { "id": "0060892", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060892" } ], "weight": 0.0 }, { "disease_id": "DOID:0080855", "name": "Parkinsonism", "description": "A movement disorder that is characterized by disturbances of balance, gait and posture.", "url": "https://disease-ontology.org/term/DOID:0080855", "evidence": [ { "id": "0080855", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080855" } ], "weight": 0.0 }, { "disease_id": "DOID:0081292", "name": "traumatic brain injury", "description": "A brain disease that is characterized by brain dysfunction caused by an outside force, usually a violent blow to the head.", "url": "https://disease-ontology.org/term/DOID:0081292", "evidence": [ { "id": "0081292", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081292" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:10914", "name": "amnestic disorder", "description": "A cognitive disorder where the memory is disturbed or lost and involves the loss of memories previously established, loss of the ability to create new memories, or loss of the ability to learn new information.", "url": "https://disease-ontology.org/term/DOID:10914", "evidence": [ { "id": "10914", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10914" } ], "weight": 0.0 }, { "disease_id": "DOID:11870", "name": "Pick's disease", "description": "A frontotemporal dementia that is characterized by a spectrum of neuropsychiatric symptoms ranging from those that affect the patient's personality to those that cause a decline in cognitive function.", "url": "https://disease-ontology.org/term/DOID:11870", "evidence": [ { "id": "11870", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11870" } ], "weight": 0.0 }, { "disease_id": "DOID:11949", "name": "Creutzfeldt-Jakob disease", "description": "", "url": "https://disease-ontology.org/term/DOID:11949", "evidence": [ { "id": "11949", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11949" } ], "weight": 0.0 }, { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:1307", "name": "dementia", "description": "A cognitive disorder resulting from a loss of brain function affecting memory, thinking, language, judgement and behavior.", "url": "https://disease-ontology.org/term/DOID:1307", "evidence": [ { "id": "1307", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1307" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:1561", "name": "cognitive disorder", "description": "A disease of mental health that affects cognitive functions including memory processing, perception and problem solving.", "url": "https://disease-ontology.org/term/DOID:1561", "evidence": [ { "id": "1561", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1561" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:2316", "name": "brain ischemia", "description": "An ischemia that is characterized by insufficient blood flow to the brain to meet metabolic demand.", "url": "https://disease-ontology.org/term/DOID:2316", "evidence": [ { "id": "2316", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2316" } ], "weight": 0.0 }, { "disease_id": "DOID:332", "name": "amyotrophic lateral sclerosis", "description": "A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.", "url": "https://disease-ontology.org/term/DOID:332", "evidence": [ { "id": "332", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:332" } ], "weight": 0.0 }, { "disease_id": "DOID:3328", "name": "temporal lobe epilepsy", "description": "A focal epilepsy that is characterized by recurrent, unprovoked focal seizures that originate in the temporal lobe of the brain and last about one or two minutes.", "url": "https://disease-ontology.org/term/DOID:3328", "evidence": [ { "id": "3328", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3328" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 }, { "disease_id": "DOID:678", "name": "progressive supranuclear palsy", "description": "A movement disease that is characterized by serious and progressive problems with control of gait and balance, along with complex eye movement and thinking problems. It involves gradual deterioration and death of specific volumes of the brain.", "url": "https://disease-ontology.org/term/DOID:678", "evidence": [ { "id": "678", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:678" } ], "weight": 0.0 }, { "disease_id": "DOID:680", "name": "tauopathy", "description": "A neurodegenerative disease that has_material_basis_in the pathological aggregation of tau protein in so-called neurofibrillary tangles (NFT) in the human brain.", "url": "https://disease-ontology.org/term/DOID:680", "evidence": [ { "id": "680", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:680" } ], "weight": 0.0 }, { "disease_id": "DOID:8725", "name": "vascular dementia", "description": "A dementia that involves impairments in cognitive function caused by problems in blood vessels that feed the brain.", "url": "https://disease-ontology.org/term/DOID:8725", "evidence": [ { "id": "8725", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8725" } ], "weight": 0.0 }, { "disease_id": "DOID:9255", "name": "frontotemporal dementia", "description": "A dementia characterized by progressive neuronal loss predominantly involving the frontal and/or temporal lobes of the brain resulting in a gradual and progressive decline in behavior or language.", "url": "https://disease-ontology.org/term/DOID:9255", "evidence": [ { "id": "9255", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9255" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q9VB15", "url": "https://www.uniprot.org/uniprotkb/Q9VB15" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "Q9VB15", "url": "https://www.uniprot.org/uniprotkb/Q9VB15" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q9VB15", "url": "https://www.uniprot.org/uniprotkb/Q9VB15" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "Q9VB15", "url": "https://www.uniprot.org/uniprotkb/Q9VB15" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "Q9VB15", "url": "https://www.uniprot.org/uniprotkb/Q9VB15" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q9VB15", "url": "https://www.uniprot.org/uniprotkb/Q9VB15" } ], "pmid": "" } ], "biological_process": [ { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "Q9VB15", "url": "https://www.uniprot.org/uniprotkb/Q9VB15" } ], "pmid": "" }, { "name": "rhabdomere morphogenesis", "id": "GO:0061541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061541", "evidence": [ { "database": "UniProtKB", "id": "Q9VB15", "url": "https://www.uniprot.org/uniprotkb/Q9VB15" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "Q9VB15", "url": "https://www.uniprot.org/uniprotkb/Q9VB15" } ], "pmid": "" }, { "name": "branching involved in open tracheal system development", "id": "GO:0060446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060446", "evidence": [ { "database": "UniProtKB", "id": "Q9VB15", "url": "https://www.uniprot.org/uniprotkb/Q9VB15" } ], "pmid": "" }, { "name": "lumen formation, open tracheal system", "id": "GO:0035149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035149", "evidence": [ { "database": "UniProtKB", "id": "Q9VB15", "url": "https://www.uniprot.org/uniprotkb/Q9VB15" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VB15-1", "start_pos": "486", "end_pos": "486", "site_lbl": "Thr486", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 486, "start_aa": "Thr", "end_pos": 486, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr486", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VB15-1" }, { "uniprot_canonical_ac": "Q9V435-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V435", "url": "https://www.uniprot.org/uniprotkb/Q9V435" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 890, "chemical_mass": 101860.0, "gene_names": "yuri;BG:DS05639.1;BG:DS07851.11;CG11860;CG12635;CG31732;Dmel\\CG31732;Dmel_CG31732;Yuri;yuri", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "Q9V435", "url": "https://www.uniprot.org/uniprotkb/Q9V435" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9V435", "url": "https://www.uniprot.org/uniprotkb/Q9V435" } ], "pmid": "" }, { "name": "nuclear lamina", "id": "GO:0005652", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005652", "evidence": [ { "database": "UniProtKB", "id": "Q9V435", "url": "https://www.uniprot.org/uniprotkb/Q9V435" } ], "pmid": "" }, { "name": "investment cone", "id": "GO:0070865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070865", "evidence": [ { "database": "UniProtKB", "id": "Q9V435", "url": "https://www.uniprot.org/uniprotkb/Q9V435" } ], "pmid": "" } ], "biological_process": [ { "name": "gravitaxis", "id": "GO:0042332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042332", "evidence": [ { "database": "UniProtKB", "id": "Q9V435", "url": "https://www.uniprot.org/uniprotkb/Q9V435" } ], "pmid": "" }, { "name": "protein localization to nuclear envelope", "id": "GO:0090435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090435", "evidence": [ { "database": "UniProtKB", "id": "Q9V435", "url": "https://www.uniprot.org/uniprotkb/Q9V435" } ], "pmid": "" }, { "name": "nuclear envelope organization", "id": "GO:0006998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006998", "evidence": [ { "database": "UniProtKB", "id": "Q9V435", "url": "https://www.uniprot.org/uniprotkb/Q9V435" } ], "pmid": "" }, { "name": "sperm individualization", "id": "GO:0007291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007291", "evidence": [ { "database": "UniProtKB", "id": "Q9V435", "url": "https://www.uniprot.org/uniprotkb/Q9V435" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "Q9V435", "url": "https://www.uniprot.org/uniprotkb/Q9V435" } ], "pmid": "" }, { "name": "nuclear migration", "id": "GO:0007097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007097", "evidence": [ { "database": "UniProtKB", "id": "Q9V435", "url": "https://www.uniprot.org/uniprotkb/Q9V435" } ], "pmid": "" }, { "name": "ciliary basal body organization", "id": "GO:0032053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032053", "evidence": [ { "database": "UniProtKB", "id": "Q9V435", "url": "https://www.uniprot.org/uniprotkb/Q9V435" } ], "pmid": "" }, { "name": "nuclear pore localization", "id": "GO:0051664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051664", "evidence": [ { "database": "UniProtKB", "id": "Q9V435", "url": "https://www.uniprot.org/uniprotkb/Q9V435" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "Q9V435", "url": "https://www.uniprot.org/uniprotkb/Q9V435" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V435-1" }, { "uniprot_canonical_ac": "Q9VHR2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VHR2", "url": "https://www.uniprot.org/uniprotkb/Q9VHR2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1876, "chemical_mass": 206681.0, "gene_names": "CG11729;CG42286;CT32186;GS3056;MRE1;anon-EST:Posey178;43462;BcDNA:AT05815;BcDNA:GH22170;CG11718;CG11729;CG11730;CG11731;CG11733;CG31264;CG31369;CG31462;CG42285;CG42286;CG43462;CG45263;CT32186;Dmel\\CG45263;Dmel_CG45263;GH22170;GS3056;MRE1;anon-EST:Posey178", "protein_name": "Ig-like domain-containing protein", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR2", "url": "https://www.uniprot.org/uniprotkb/Q9VHR2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR2", "url": "https://www.uniprot.org/uniprotkb/Q9VHR2" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR2", "url": "https://www.uniprot.org/uniprotkb/Q9VHR2" } ], "pmid": "" } ], "molecular_function": [ { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR2", "url": "https://www.uniprot.org/uniprotkb/Q9VHR2" } ], "pmid": "" } ], "biological_process": [ { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR2", "url": "https://www.uniprot.org/uniprotkb/Q9VHR2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VHR2-1", "start_pos": "1617", "end_pos": "1617", "site_lbl": "Thr1617", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1617, "start_aa": "Thr", "end_pos": 1617, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1617", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VHR2-1", "start_pos": "1652", "end_pos": "1652", "site_lbl": "Thr1652", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1652, "start_aa": "Thr", "end_pos": 1652, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1652", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VHR2-1", "start_pos": "1838", "end_pos": "1838", "site_lbl": "Thr1838", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1838, "start_aa": "Thr", "end_pos": 1838, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1838", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VHR2-1", "start_pos": "326", "end_pos": "326", "site_lbl": "Ser326", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 326, "start_aa": "Ser", "end_pos": 326, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser326", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VHR2", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VHR2" } ] } ] }, { "uniprot_canonical_ac": "Q9VHR2-1", "start_pos": "334", "end_pos": "334", "site_lbl": "Thr334", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 334, "start_aa": "Thr", "end_pos": 334, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr334", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VHR2", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VHR2" } ] } ] } ], "record_id": "Q9VHR2-1" }, { "uniprot_canonical_ac": "M9NFQ7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 962, "chemical_mass": 96880.0, "gene_names": "Rbfox1;A2BP1;A2bp1;BcDNA:GM06073;CG14155;CG18441;CG32062;Dmel\\CG32062;Dmel_CG32062;Rbfox1;Rbox1;cg18441;dA2BP1;rbfox1", "protein_name": "", "disease": [ { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:11722", "name": "myotonic dystrophy type 1", "description": "A myotonic disease that is characterized by progressive muscle wasting and weakness affecting the distal skeletal and smooth muscles of lower legs, hands, neck, and face along with myotonia and cataracts and has_material_basis_in the autosomal dominant inheritance of the DMPK gene containing an expansion of a CTG trinucleotide repeat in the non-coding region.", "url": "https://disease-ontology.org/term/DOID:11722", "evidence": [ { "id": "11722", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11722" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 }, { "disease_id": "DOID:3454", "name": "brain infarction", "description": "A cerebrovascular disease that is characterized by tissue necrosis located_in the brain, resulting from inadequate blood flow through the brain.", "url": "https://disease-ontology.org/term/DOID:3454", "evidence": [ { "id": "3454", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3454" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9955", "name": "hypoplastic left heart syndrome", "description": "A congenital heart disease characterized by abnormal development of the left-sided structures of the heart.", "url": "https://disease-ontology.org/term/DOID:9955", "evidence": [ { "id": "9955", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9955" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "nuclear stress granule", "id": "GO:0097165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097165", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "negative regulation of translation", "id": "GO:0017148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017148", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "imaginal disc-derived wing vein specification", "id": "GO:0007474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007474", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "germarium-derived oocyte differentiation", "id": "GO:0030706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030706", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "memory", "id": "GO:0007613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007613", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "Cajal body organization", "id": "GO:0030576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030576", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "cellular response to chemical stress", "id": "GO:0062197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062197", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "molecular condensate scaffold activity", "id": "GO:0140693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140693", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9NFQ7-1", "start_pos": "284", "end_pos": "284", "site_lbl": "Thr284", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 284, "start_aa": "Thr", "end_pos": 284, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr284", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9NFQ7-1" }, { "uniprot_canonical_ac": "Q7KVY9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KVY9", "url": "https://www.uniprot.org/uniprotkb/Q7KVY9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2777, "chemical_mass": 297664.0, "gene_names": "PsGEF;CG14045;CG14047;CG43947;DmPsGEF;Dmel\\CG43947;Dmel_CG43947;EG:BACH48C10.4;EG:BACH7M4.1;EG:BACH7M4.2;FBgn0264598;PsGEF;PsGef;null;psGEF", "protein_name": "", "disease": [], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "Q7KVY9", "url": "https://www.uniprot.org/uniprotkb/Q7KVY9" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "Q7KVY9", "url": "https://www.uniprot.org/uniprotkb/Q7KVY9" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of Rac protein signal transduction", "id": "GO:0035022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035022", "evidence": [ { "database": "UniProtKB", "id": "Q7KVY9", "url": "https://www.uniprot.org/uniprotkb/Q7KVY9" } ], "pmid": "" }, { "name": "regulation of actin filament polymerization", "id": "GO:0030833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030833", "evidence": [ { "database": "UniProtKB", "id": "Q7KVY9", "url": "https://www.uniprot.org/uniprotkb/Q7KVY9" } ], "pmid": "" }, { "name": "positive regulation of ruffle assembly", "id": "GO:1900029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900029", "evidence": [ { "database": "UniProtKB", "id": "Q7KVY9", "url": "https://www.uniprot.org/uniprotkb/Q7KVY9" } ], "pmid": "" }, { "name": "mushroom body development", "id": "GO:0016319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016319", "evidence": [ { "database": "UniProtKB", "id": "Q7KVY9", "url": "https://www.uniprot.org/uniprotkb/Q7KVY9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q7KVY9", "url": "https://www.uniprot.org/uniprotkb/Q7KVY9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q7KVY9", "url": "https://www.uniprot.org/uniprotkb/Q7KVY9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q7KVY9", "url": "https://www.uniprot.org/uniprotkb/Q7KVY9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7KVY9-1", "start_pos": "1756", "end_pos": "1756", "site_lbl": "Thr1756", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1756, "start_aa": "Thr", "end_pos": 1756, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1756", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q7KVY9-1" }, { "uniprot_canonical_ac": "M9PHU0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PHU0", "url": "https://www.uniprot.org/uniprotkb/M9PHU0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2263, "chemical_mass": 243755.0, "gene_names": "CG12432;CG8557;CG12432;CG43658;CG8557;Dmel\\CG43658;Dmel_CG43658", "protein_name": "DH domain-containing protein", "disease": [ { "disease_id": "DOID:0050668", "name": "alcohol-related birth defects", "description": "A fetal alcohol spectrum disorder that results in damage to organs, bones, or muscles due to prenatal alcohol exposure.", "url": "https://disease-ontology.org/term/DOID:0050668", "evidence": [ { "id": "0050668", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050668" } ], "weight": 0.0 }, { "disease_id": "DOID:0050933", "name": "ovarian serous carcinoma", "description": "An ovarian carcinoma that has_material_basis_in the lining of the ovary and produces a serum-like fluid.", "url": "https://disease-ontology.org/term/DOID:0050933", "evidence": [ { "id": "0050933", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050933" } ], "weight": 0.0 }, { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:6212", "name": "ovarian endometrial cancer", "description": "An ovary epithelial cancer that has_material_basis_in the endometrium and is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:6212", "evidence": [ { "id": "6212", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6212" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9PHU0", "url": "https://www.uniprot.org/uniprotkb/M9PHU0" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of stress fiber assembly", "id": "GO:0051496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051496", "evidence": [ { "database": "UniProtKB", "id": "M9PHU0", "url": "https://www.uniprot.org/uniprotkb/M9PHU0" } ], "pmid": "" }, { "name": "positive regulation of Rho protein signal transduction", "id": "GO:0035025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035025", "evidence": [ { "database": "UniProtKB", "id": "M9PHU0", "url": "https://www.uniprot.org/uniprotkb/M9PHU0" } ], "pmid": "" }, { "name": "imaginal disc-derived leg morphogenesis", "id": "GO:0007480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007480", "evidence": [ { "database": "UniProtKB", "id": "M9PHU0", "url": "https://www.uniprot.org/uniprotkb/M9PHU0" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "M9PHU0", "url": "https://www.uniprot.org/uniprotkb/M9PHU0" } ], "pmid": "" } ], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "M9PHU0", "url": "https://www.uniprot.org/uniprotkb/M9PHU0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PHU0-1", "start_pos": "369", "end_pos": "369", "site_lbl": "Thr369", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 369, "start_aa": "Thr", "end_pos": 369, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr369", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9PHU0-1" }, { "uniprot_canonical_ac": "Q7KUQ6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KUQ6", "url": "https://www.uniprot.org/uniprotkb/Q7KUQ6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2147, "chemical_mass": 245500.0, "gene_names": "Lmpt;BcDNA:RE37250;CG11914;CG11915;CG11916;CG32171;CG33256;CG42679;CG9959;Dmel\\CG42679;Dmel_CG42679;Lmpt;lmpt", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q7KUQ6", "url": "https://www.uniprot.org/uniprotkb/Q7KUQ6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q7KUQ6", "url": "https://www.uniprot.org/uniprotkb/Q7KUQ6" } ], "pmid": "" }, { "name": "I band", "id": "GO:0031674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031674", "evidence": [ { "database": "UniProtKB", "id": "Q7KUQ6", "url": "https://www.uniprot.org/uniprotkb/Q7KUQ6" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q7KUQ6", "url": "https://www.uniprot.org/uniprotkb/Q7KUQ6" } ], "pmid": "" } ], "biological_process": [ { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "Q7KUQ6", "url": "https://www.uniprot.org/uniprotkb/Q7KUQ6" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "Q7KUQ6", "url": "https://www.uniprot.org/uniprotkb/Q7KUQ6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7KUQ6-1", "start_pos": "1114", "end_pos": "1114", "site_lbl": "Thr1114", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1114, "start_aa": "Thr", "end_pos": 1114, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1114", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q7KUQ6-1" }, { "uniprot_canonical_ac": "M9PFZ1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PFZ1", "url": "https://www.uniprot.org/uniprotkb/M9PFZ1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 773, "chemical_mass": 78192.0, "gene_names": "Nopp140;CG7421;DmNopp140;Dmel\\CG7421;Dmel_CG7421;NCL;Nopp- 140;Nopp140;nopp140", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "M9PFZ1", "url": "https://www.uniprot.org/uniprotkb/M9PFZ1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "M9PFZ1", "url": "https://www.uniprot.org/uniprotkb/M9PFZ1" } ], "pmid": "" } ], "biological_process": [ { "name": "ribosome biogenesis", "id": "GO:0042254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042254", "evidence": [ { "database": "UniProtKB", "id": "M9PFZ1", "url": "https://www.uniprot.org/uniprotkb/M9PFZ1" } ], "pmid": "" }, { "name": "rRNA 2'-O-methylation", "id": "GO:0000451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000451", "evidence": [ { "database": "UniProtKB", "id": "M9PFZ1", "url": "https://www.uniprot.org/uniprotkb/M9PFZ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PFZ1-1", "start_pos": "339", "end_pos": "339", "site_lbl": "Thr339", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 339, "start_aa": "Thr", "end_pos": 339, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr339", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PFZ1-1", "start_pos": "371", "end_pos": "371", "site_lbl": "Thr371", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 371, "start_aa": "Thr", "end_pos": 371, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr371", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PFZ1-1", "start_pos": "403", "end_pos": "403", "site_lbl": "Thr403", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 403, "start_aa": "Thr", "end_pos": 403, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr403", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PFZ1-1", "start_pos": "408", "end_pos": "408", "site_lbl": "Thr408", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 408, "start_aa": "Thr", "end_pos": 408, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr408", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PFZ1-1", "start_pos": "436", "end_pos": "436", "site_lbl": "Thr436", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 436, "start_aa": "Thr", "end_pos": 436, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr436", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9PFZ1-1" }, { "uniprot_canonical_ac": "M9PCE3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PCE3", "url": "https://www.uniprot.org/uniprotkb/M9PCE3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1901, "chemical_mass": 213595.0, "gene_names": "Dmel\\CG18304;CG13774;CG18304;Dmel\\CG18304;Dmel_CG18304", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PCE3-1" }, { "uniprot_canonical_ac": "M9PB01-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PB01", "url": "https://www.uniprot.org/uniprotkb/M9PB01" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2397, "chemical_mass": 262843.0, "gene_names": "Wdr62;CG7337;Dmel\\CG7337;Dmel_CG7337;Q0E8U7_DROME;WDR62;Wdr62;wdr62", "protein_name": "", "disease": [ { "disease_id": "DOID:0070293", "name": "primary autosomal recessive microcephaly 2 with or without cortical malformations", "description": "A primary autosomal recessive microcephaly that has_material_basis_in homozygous or compound heterozygous mutation in the WDR62 gene on chromosome 19q13.", "url": "https://disease-ontology.org/term/DOID:0070293", "evidence": [ { "id": "0070293", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070293" } ], "weight": 0.0 }, { "disease_id": "DOID:0070296", "name": "autosomal recessive primary microcephaly", "description": "A primary microcephaly characterized by microcephaly present at birth, where the brain is small but has normal architecture, and nonprogressive mental retardation that has_material_basis_in an autosomal recessive mutation.", "url": "https://disease-ontology.org/term/DOID:0070296", "evidence": [ { "id": "0070296", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070296" } ], "weight": 0.0 }, { "disease_id": "DOID:0080918", "name": "polymicrogyria", "description": "A brain disease that is characterized by malformation of the developing brain characterized by abnormal cortical lamination and an unusual folding pattern of the cerebral cortex such that all or part of the brain surface is taken up by an excessive number of small folds (gyri).", "url": "https://disease-ontology.org/term/DOID:0080918", "evidence": [ { "id": "0080918", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080918" } ], "weight": 0.0 }, { "disease_id": "DOID:0111127", "name": "nephronophthisis 20", "description": "A nephronophthisis that has_material_basis_in homozygous or compound heterozygous mutation in the MAPKBP1 gene on chromosome 15q15.", "url": "https://disease-ontology.org/term/DOID:0111127", "evidence": [ { "id": "0111127", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111127" } ], "weight": 0.0 }, { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 }, { "disease_id": "DOID:10907", "name": "microcephaly", "description": "A congenital nervous system abnormality that is characterized by a significantly smaller than normal head in infants.", "url": "https://disease-ontology.org/term/DOID:10907", "evidence": [ { "id": "10907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10907" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "M9PB01", "url": "https://www.uniprot.org/uniprotkb/M9PB01" } ], "pmid": "" }, { "name": "interphase microtubule organizing center", "id": "GO:0031021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031021", "evidence": [ { "database": "UniProtKB", "id": "M9PB01", "url": "https://www.uniprot.org/uniprotkb/M9PB01" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "M9PB01", "url": "https://www.uniprot.org/uniprotkb/M9PB01" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "M9PB01", "url": "https://www.uniprot.org/uniprotkb/M9PB01" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "M9PB01", "url": "https://www.uniprot.org/uniprotkb/M9PB01" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PB01-1", "start_pos": "223", "end_pos": "223", "site_lbl": "Thr223", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 223, "start_aa": "Thr", "end_pos": 223, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr223", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9PB01-1" }, { "uniprot_canonical_ac": "Q9VIM4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VIM4", "url": "https://www.uniprot.org/uniprotkb/Q9VIM4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 117, "chemical_mass": 13869.0, "gene_names": "38C.48;Dmel\\CG15130;38C.48;CG15130;Dmel\\CG15130;Dmel_CG15130", "protein_name": "Transmembrane inner ear expressed protein", "disease": [ { "disease_id": "DOID:0110512", "name": "autosomal recessive nonsyndromic deafness 6", "description": "An autosomal recessive nonsyndromic deafness that is characterized by prelingual onset with severe to profound, stable hearing loss and has_material_basis_in mutation in the TMIE gene on chromosome 3p21.", "url": "https://disease-ontology.org/term/DOID:0110512", "evidence": [ { "id": "0110512", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110512" } ], "weight": 0.0 }, { "disease_id": "DOID:10003", "name": "sensorineural hearing loss", "description": "An inner ear disease that is characterized by hearing loss resulting from damage to the cochlea, auditory nerve and/or brainstem.", "url": "https://disease-ontology.org/term/DOID:10003", "evidence": [ { "id": "10003", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10003" } ], "weight": 0.0 } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VIM4-1" }, { "uniprot_canonical_ac": "Q9V9N3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V9N3", "url": "https://www.uniprot.org/uniprotkb/Q9V9N3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 425, "chemical_mass": 48041.0, "gene_names": "Dmel\\CG3635;CG3635;Dmel\\CG3635;Dmel_CG3635", "protein_name": "Lipase", "disease": [ { "disease_id": "DOID:0080217", "name": "lysosomal acid lipase deficiency", "description": "A lipid storage disease characterized by dyslipidemia and accumulation of cholesteryl esters and triglycerides within various organs that has_material_basis_in homozygous or compound heterozygous mutation in the LIPA gene on chromosome 10q23.31.", "url": "https://disease-ontology.org/term/DOID:0080217", "evidence": [ { "id": "0080217", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080217" } ], "weight": 0.0 }, { "disease_id": "DOID:14497", "name": "Wolman disease", "description": "A lysosomal acid lipase deficiency characterized by infantile onset of rapidly progressive accumulation of cholesteryl esters and triglycerides throughout the body, resulting in hepatosplenomegaly, severe malnutrition, jaundice, vomiting, diarrhea, steatorrhea. Death usually occurs within the first year of life.", "url": "https://disease-ontology.org/term/DOID:14497", "evidence": [ { "id": "14497", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14497" } ], "weight": 0.0 } ], "biological_process": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "Q9V9N3", "url": "https://www.uniprot.org/uniprotkb/Q9V9N3" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "Q9V9N3", "url": "https://www.uniprot.org/uniprotkb/Q9V9N3" } ], "pmid": "" } ], "molecular_function": [ { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "Q9V9N3", "url": "https://www.uniprot.org/uniprotkb/Q9V9N3" } ], "pmid": "" }, { "name": "lipase activity", "id": "GO:0016298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016298", "evidence": [ { "database": "UniProtKB", "id": "Q9V9N3", "url": "https://www.uniprot.org/uniprotkb/Q9V9N3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9V9N3-1", "start_pos": "343", "end_pos": "343", "site_lbl": "Thr343", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 343, "start_aa": "Thr", "end_pos": 343, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr343", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9V9N3-1" }, { "uniprot_canonical_ac": "M9PC26-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PC26", "url": "https://www.uniprot.org/uniprotkb/M9PC26" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2021, "chemical_mass": 225996.0, "gene_names": "CG10020;CG31772;CG31959;CG10020;CG31772;CG31959;CG43707;Dmel\\CG43707;Dmel_CG43707", "protein_name": "", "disease": [], "cellular_component": [ { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "M9PC26", "url": "https://www.uniprot.org/uniprotkb/M9PC26" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PC26-1", "start_pos": "829", "end_pos": "829", "site_lbl": "Thr829", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 829, "start_aa": "Thr", "end_pos": 829, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr829", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PC26-1", "start_pos": "947", "end_pos": "947", "site_lbl": "Thr947", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 947, "start_aa": "Thr", "end_pos": 947, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr947", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PC26-1", "start_pos": "966", "end_pos": "966", "site_lbl": "Thr966", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 966, "start_aa": "Thr", "end_pos": 966, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr966", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9PC26-1" }, { "uniprot_canonical_ac": "Q8IPJ4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IPJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IPJ4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 711, "chemical_mass": 78469.0, "gene_names": "Nhe3;CG11328;DmNHE3;Dmel\\CG11328;Dmel_CG11328;NHE3;NHE;Nhe3;nhe3", "protein_name": "Sodium/hydrogen exchanger", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0060825", "name": "Christianson syndrome", "description": "A syndromic X-linked intellectual disability characterized by microcephaly, impaired ocular movements, progressive severe global developmental delay, developmental regression, hypotonia, abnormal movements, and early-onset seizures of variable types that has_material_basis_in mutation in hemizygous mutation in the SLC9A6 gene on chromosome Xq26.", "url": "https://disease-ontology.org/term/DOID:0060825", "evidence": [ { "id": "0060825", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060825" } ], "weight": 0.0 }, { "disease_id": "DOID:0111844", "name": "X-linked intellectual developmental disorder 108", "description": "A syndromic X-linked intellectual disability characterized by global developmental delay, delayed walking, and poor speech acquisition that has_material_basis_in hemizygous mutation in the SLC9A7 gene on chromosome Xp11.3.", "url": "https://disease-ontology.org/term/DOID:0111844", "evidence": [ { "id": "0111844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111844" } ], "weight": 0.0 }, { "disease_id": "DOID:12849", "name": "autistic disorder", "description": "An autism spectrum disorder that is characterized by symptoms across all three symptom domains (communication, social, restricted repetitive interests and behaviors), delayed language development, and symptom onset prior to age 3 years.", "url": "https://disease-ontology.org/term/DOID:12849", "evidence": [ { "id": "12849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12849" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "sodium:proton antiporter activity", "id": "GO:0015385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015385", "evidence": [ { "database": "UniProtKB", "id": "Q8IPJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IPJ4" } ], "pmid": "" }, { "name": "potassium:proton antiporter activity", "id": "GO:0015386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015386", "evidence": [ { "database": "UniProtKB", "id": "Q8IPJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IPJ4" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q8IPJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IPJ4" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "Q8IPJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IPJ4" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "Q8IPJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IPJ4" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "Q8IPJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IPJ4" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of pH", "id": "GO:0006885", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006885", "evidence": [ { "database": "UniProtKB", "id": "Q8IPJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IPJ4" } ], "pmid": "" }, { "name": "regulation of intracellular pH", "id": "GO:0051453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051453", "evidence": [ { "database": "UniProtKB", "id": "Q8IPJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IPJ4" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "Q8IPJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IPJ4" } ], "pmid": "" }, { "name": "sodium ion import across plasma membrane", "id": "GO:0098719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098719", "evidence": [ { "database": "UniProtKB", "id": "Q8IPJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IPJ4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IPJ4-1" }, { "uniprot_canonical_ac": "M9PCG3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PCG3", "url": "https://www.uniprot.org/uniprotkb/M9PCG3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2298, "chemical_mass": 260629.0, "gene_names": "Ziz;BcDNA:RH71439;CG15819;CG42533;CG6630;Dm ziz;Dmel\\CG42533;Dmel_CG42533;Ziz", "protein_name": "", "disease": [], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "M9PCG3", "url": "https://www.uniprot.org/uniprotkb/M9PCG3" } ], "pmid": "" } ], "biological_process": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "M9PCG3", "url": "https://www.uniprot.org/uniprotkb/M9PCG3" } ], "pmid": "" }, { "name": "regulation of Rho protein signal transduction", "id": "GO:0035023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035023", "evidence": [ { "database": "UniProtKB", "id": "M9PCG3", "url": "https://www.uniprot.org/uniprotkb/M9PCG3" } ], "pmid": "" }, { "name": "compound eye development", "id": "GO:0048749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048749", "evidence": [ { "database": "UniProtKB", "id": "M9PCG3", "url": "https://www.uniprot.org/uniprotkb/M9PCG3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PCG3-1", "start_pos": "861", "end_pos": "861", "site_lbl": "Thr861", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 861, "start_aa": "Thr", "end_pos": 861, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr861", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9PCG3-1" }, { "uniprot_canonical_ac": "M9PHU7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PHU7", "url": "https://www.uniprot.org/uniprotkb/M9PHU7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1248, "chemical_mass": 135157.0, "gene_names": "CG43113;CG5741;CG43113;CG43783;CG5741;Dmel\\CG43783;Dmel_CG43783", "protein_name": "SMP-LTD domain-containing protein", "disease": [], "biological_process": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "M9PHU7", "url": "https://www.uniprot.org/uniprotkb/M9PHU7" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "M9PHU7", "url": "https://www.uniprot.org/uniprotkb/M9PHU7" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "M9PHU7", "url": "https://www.uniprot.org/uniprotkb/M9PHU7" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "M9PHU7", "url": "https://www.uniprot.org/uniprotkb/M9PHU7" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "M9PHU7", "url": "https://www.uniprot.org/uniprotkb/M9PHU7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PHU7-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Thr172", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 172, "start_aa": "Thr", "end_pos": 172, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr172", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9PHU7-1" }, { "uniprot_canonical_ac": "M9PF47-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PF47", "url": "https://www.uniprot.org/uniprotkb/M9PF47" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 760, "chemical_mass": 82239.0, "gene_names": "FoxK;CG11799;DmLD16137;DmMNF;Dmel\\CG11799;Dmel_CG11799;FoxK;MNF;Mnf;dFoxK;fd68A;fork head transcription factor long isoform;fork head transcription factor short isoform", "protein_name": "", "disease": [], "biological_process": [ { "name": "visceral mesoderm-endoderm interaction involved in midgut development", "id": "GO:0007495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007495", "evidence": [ { "database": "UniProtKB", "id": "M9PF47", "url": "https://www.uniprot.org/uniprotkb/M9PF47" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "M9PF47", "url": "https://www.uniprot.org/uniprotkb/M9PF47" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "M9PF47", "url": "https://www.uniprot.org/uniprotkb/M9PF47" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "M9PF47", "url": "https://www.uniprot.org/uniprotkb/M9PF47" } ], "pmid": "" }, { "name": "midgut development", "id": "GO:0007494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007494", "evidence": [ { "database": "UniProtKB", "id": "M9PF47", "url": "https://www.uniprot.org/uniprotkb/M9PF47" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "M9PF47", "url": "https://www.uniprot.org/uniprotkb/M9PF47" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "M9PF47", "url": "https://www.uniprot.org/uniprotkb/M9PF47" } ], "pmid": "" }, { "name": "cellular response to virus", "id": "GO:0098586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098586", "evidence": [ { "database": "UniProtKB", "id": "M9PF47", "url": "https://www.uniprot.org/uniprotkb/M9PF47" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "M9PF47", "url": "https://www.uniprot.org/uniprotkb/M9PF47" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "M9PF47", "url": "https://www.uniprot.org/uniprotkb/M9PF47" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "M9PF47", "url": "https://www.uniprot.org/uniprotkb/M9PF47" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "M9PF47", "url": "https://www.uniprot.org/uniprotkb/M9PF47" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PF47", "url": "https://www.uniprot.org/uniprotkb/M9PF47" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PF47-1" }, { "uniprot_canonical_ac": "M9PCD4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1214, "chemical_mass": 136092.0, "gene_names": "Liprin-alpha;CG11199;DLiprin-alpha;DLiprin;Dliprin-alpha;Dmel\\CG11199;Dmel_CG11199;LIP.1;LIP1;LIP;LPR;Liprin-alpha;Liprin;lip-alpha;liprin-alpha;liprin;lpr;oos", "protein_name": "", "disease": [], "biological_process": [ { "name": "presynapse assembly", "id": "GO:0099054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099054", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "synaptic assembly at neuromuscular junction", "id": "GO:0051124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051124", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "synapse assembly", "id": "GO:0007416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007416", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "anterograde synaptic vesicle transport", "id": "GO:0048490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048490", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "axon extension", "id": "GO:0048675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048675", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "regulation of axon extension involved in axon guidance", "id": "GO:0048841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048841", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "retinal ganglion cell axon guidance", "id": "GO:0031290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031290", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "photoreceptor cell morphogenesis", "id": "GO:0008594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008594", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "axon target recognition", "id": "GO:0007412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007412", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "R7 cell development", "id": "GO:0045467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045467", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "synaptic vesicle localization", "id": "GO:0097479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097479", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "presynaptic active zone organization", "id": "GO:1990709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990709", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "synapse organization", "id": "GO:0050808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050808", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" } ], "cellular_component": [ { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "presynaptic active zone", "id": "GO:0048786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048786", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "axon cytoplasm", "id": "GO:1904115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904115", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "presynaptic cytosol", "id": "GO:0099523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099523", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PCD4-1" }, { "uniprot_canonical_ac": "Q9VKI0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VKI0", "url": "https://www.uniprot.org/uniprotkb/Q9VKI0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2189, "chemical_mass": 251504.0, "gene_names": "cmet;CENP-E meta;CENP-E;CENP-META;CENP-Meta;CENPE;CENPmeta;CG6392;Cenp-E;Cenp-M;Cenp-meta;Cenp_E;Cmet;DmCmeta;DmCmet;Dmel\\CG6392;Dmel_CG6392;KIF 10;KIF10;cmet;l(2)04431", "protein_name": "", "disease": [ { "disease_id": "DOID:0070283", "name": "primary autosomal recessive microcephaly 13", "description": "A primary autosomal recessive microcephaly that has_material_basis_in homozygous or compound heterozygous mutation in the CENPE gene on chromosome 4q24.", "url": "https://disease-ontology.org/term/DOID:0070283", "evidence": [ { "id": "0070283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070283" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VKI0", "url": "https://www.uniprot.org/uniprotkb/Q9VKI0" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q9VKI0", "url": "https://www.uniprot.org/uniprotkb/Q9VKI0" } ], "pmid": "" }, { "name": "plus-end-directed microtubule motor activity", "id": "GO:0008574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008574", "evidence": [ { "database": "UniProtKB", "id": "Q9VKI0", "url": "https://www.uniprot.org/uniprotkb/Q9VKI0" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "Q9VKI0", "url": "https://www.uniprot.org/uniprotkb/Q9VKI0" } ], "pmid": "" } ], "cellular_component": [ { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "Q9VKI0", "url": "https://www.uniprot.org/uniprotkb/Q9VKI0" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q9VKI0", "url": "https://www.uniprot.org/uniprotkb/Q9VKI0" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "Q9VKI0", "url": "https://www.uniprot.org/uniprotkb/Q9VKI0" } ], "pmid": "" } ], "biological_process": [ { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "Q9VKI0", "url": "https://www.uniprot.org/uniprotkb/Q9VKI0" } ], "pmid": "" }, { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "Q9VKI0", "url": "https://www.uniprot.org/uniprotkb/Q9VKI0" } ], "pmid": "" }, { "name": "mitotic metaphase chromosome alignment", "id": "GO:0007080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007080", "evidence": [ { "database": "UniProtKB", "id": "Q9VKI0", "url": "https://www.uniprot.org/uniprotkb/Q9VKI0" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "Q9VKI0", "url": "https://www.uniprot.org/uniprotkb/Q9VKI0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VKI0-1" }, { "uniprot_canonical_ac": "Q9VIM1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VIM1", "url": "https://www.uniprot.org/uniprotkb/Q9VIM1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 714, "chemical_mass": 77801.0, "gene_names": "CG11016;CG11017;Dmel\\CG31688;38C.49;38C.52;CG11016;CG11017;CG11019;CG18597;CG31688-PA;CG31688;Dmel\\CG31688;Dmel_CG31688", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VIM1-1" }, { "uniprot_canonical_ac": "M9PER3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PER3", "url": "https://www.uniprot.org/uniprotkb/M9PER3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 599, "chemical_mass": 68741.0, "gene_names": "Dmel\\CG13293;CG13293;Dmel\\CG13293;Dmel_CG13293", "protein_name": "Protein SCAI", "disease": [], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "M9PER3", "url": "https://www.uniprot.org/uniprotkb/M9PER3" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "M9PER3", "url": "https://www.uniprot.org/uniprotkb/M9PER3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PER3", "url": "https://www.uniprot.org/uniprotkb/M9PER3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PER3-1" }, { "uniprot_canonical_ac": "M9PF57-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PF57", "url": "https://www.uniprot.org/uniprotkb/M9PF57" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1385, "chemical_mass": 154599.0, "gene_names": "BcDNA:RH19933;CG14172;CG32049;CG32051;CG8154;CG8163;BcDNA:RE55923;BcDNA:RH19933;CG14172;CG32049;CG32050;CG32051;CG33205;CG43897;CG8154;CG8163;Dmel\\CG43897;Dmel_CG43897", "protein_name": "Zasp-like motif domain-containing protein", "disease": [], "biological_process": [ { "name": "mesoderm development", "id": "GO:0007498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007498", "evidence": [ { "database": "UniProtKB", "id": "M9PF57", "url": "https://www.uniprot.org/uniprotkb/M9PF57" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "M9PF57", "url": "https://www.uniprot.org/uniprotkb/M9PF57" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9PF57", "url": "https://www.uniprot.org/uniprotkb/M9PF57" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "M9PF57", "url": "https://www.uniprot.org/uniprotkb/M9PF57" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PF57-1", "start_pos": "353", "end_pos": "353", "site_lbl": "Thr353", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 353, "start_aa": "Thr", "end_pos": 353, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr353", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PF57-1", "start_pos": "471", "end_pos": "471", "site_lbl": "Thr471", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 471, "start_aa": "Thr", "end_pos": 471, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr471", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PF57-1", "start_pos": "938", "end_pos": "938", "site_lbl": "Thr938", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 938, "start_aa": "Thr", "end_pos": 938, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr938", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9PF57-1" }, { "uniprot_canonical_ac": "M9PER1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 447, "chemical_mass": 47924.0, "gene_names": "Atg18a;ATG18.1;ATG18a;ATG18;Atg18A;Atg18a;Atg18;CG7986;Dmel\\CG7986;Dmel_CG7986;atg18.1;atg18a;atg18", "protein_name": "", "disease": [ { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 } ], "biological_process": [ { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "regulation of defense response to virus", "id": "GO:0050688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050688", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "glycophagy", "id": "GO:0061723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061723", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "larval midgut histolysis", "id": "GO:0035069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035069", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "larval midgut cell programmed cell death", "id": "GO:0035096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035096", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "protein localization to phagophore assembly site", "id": "GO:0034497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034497", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "T-tubule organization", "id": "GO:0033292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033292", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "autophagy of mitochondrion", "id": "GO:0000422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000422", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "nucleophagy", "id": "GO:0044804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044804", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "pexophagy", "id": "GO:0000425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000425", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,5-bisphosphate binding", "id": "GO:0080025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080025", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PER1-1" }, { "uniprot_canonical_ac": "M9PGC0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PGC0", "url": "https://www.uniprot.org/uniprotkb/M9PGC0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 368, "chemical_mass": 42260.0, "gene_names": "M6;CG7540;Dmel\\CG7540;Dmel_CG7540;M6;dM6a;m6", "protein_name": "", "disease": [ { "disease_id": "DOID:0110773", "name": "hereditary spastic paraplegia 2", "description": "A hereditary spastic paraplegia that has_material_basis_in mutation in the PLP1 gene on chromosome Xq22.2.", "url": "https://disease-ontology.org/term/DOID:0110773", "evidence": [ { "id": "0110773", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110773" } ], "weight": 0.0 }, { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 }, { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:3210", "name": "Pelizaeus-Merzbacher disease", "description": "A hypomyelinating leukodystrophy characterized by impaired myelin formation, nystagmus, spastic quadriplegia, ataxia, and developmental delay that has_material_basis_in mutation in the PLP1 gene on chromosome Xq22.", "url": "https://disease-ontology.org/term/DOID:3210", "evidence": [ { "id": "3210", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3210" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M9PGC0", "url": "https://www.uniprot.org/uniprotkb/M9PGC0" } ], "pmid": "" }, { "name": "lateral plasma membrane", "id": "GO:0016328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016328", "evidence": [ { "database": "UniProtKB", "id": "M9PGC0", "url": "https://www.uniprot.org/uniprotkb/M9PGC0" } ], "pmid": "" }, { "name": "tricellular tight junction", "id": "GO:0061689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061689", "evidence": [ { "database": "UniProtKB", "id": "M9PGC0", "url": "https://www.uniprot.org/uniprotkb/M9PGC0" } ], "pmid": "" } ], "biological_process": [ { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "M9PGC0", "url": "https://www.uniprot.org/uniprotkb/M9PGC0" } ], "pmid": "" }, { "name": "compound eye morphogenesis", "id": "GO:0001745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001745", "evidence": [ { "database": "UniProtKB", "id": "M9PGC0", "url": "https://www.uniprot.org/uniprotkb/M9PGC0" } ], "pmid": "" }, { "name": "positive phototaxis", "id": "GO:0046956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046956", "evidence": [ { "database": "UniProtKB", "id": "M9PGC0", "url": "https://www.uniprot.org/uniprotkb/M9PGC0" } ], "pmid": "" }, { "name": "tricellular tight junction assembly", "id": "GO:1904274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904274", "evidence": [ { "database": "UniProtKB", "id": "M9PGC0", "url": "https://www.uniprot.org/uniprotkb/M9PGC0" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "M9PGC0", "url": "https://www.uniprot.org/uniprotkb/M9PGC0" } ], "pmid": "" }, { "name": "maintenance of epithelial integrity, open tracheal system", "id": "GO:0035160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035160", "evidence": [ { "database": "UniProtKB", "id": "M9PGC0", "url": "https://www.uniprot.org/uniprotkb/M9PGC0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PGC0-1" }, { "uniprot_canonical_ac": "M9PHI0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PHI0", "url": "https://www.uniprot.org/uniprotkb/M9PHI0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 887, "chemical_mass": 95553.0, "gene_names": "Hk;CG17779;CG2287;CG32688;CG34319;CG43388;Dm_X:51771;Dmel\\CG43388;Dmel_CG43388;HK;Hk;hk;lincRNA.975", "protein_name": "", "disease": [ { "disease_id": "DOID:0060410", "name": "chromosome 1p36 deletion syndrome", "description": "A chromosomal deletion syndrome that has_material_basis_in by deletion of the chromosome 1p36 region and is characterized by severe intellectual disability, a small head, deep-set eyes with straight eyebrows, midface hypoplasia, a broad, flat nose, a pointed chin and low-set ears.", "url": "https://disease-ontology.org/term/DOID:0060410", "evidence": [ { "id": "0060410", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060410" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:3328", "name": "temporal lobe epilepsy", "description": "A focal epilepsy that is characterized by recurrent, unprovoked focal seizures that originate in the temporal lobe of the brain and last about one or two minutes.", "url": "https://disease-ontology.org/term/DOID:3328", "evidence": [ { "id": "3328", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3328" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9PHI0", "url": "https://www.uniprot.org/uniprotkb/M9PHI0" } ], "pmid": "" }, { "name": "voltage-gated potassium channel complex", "id": "GO:0008076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", "evidence": [ { "database": "UniProtKB", "id": "M9PHI0", "url": "https://www.uniprot.org/uniprotkb/M9PHI0" } ], "pmid": "" } ], "molecular_function": [ { "name": "potassium channel regulator activity", "id": "GO:0015459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015459", "evidence": [ { "database": "UniProtKB", "id": "M9PHI0", "url": "https://www.uniprot.org/uniprotkb/M9PHI0" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "M9PHI0", "url": "https://www.uniprot.org/uniprotkb/M9PHI0" } ], "pmid": "" }, { "name": "voltage-gated potassium channel activity", "id": "GO:0005249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005249", "evidence": [ { "database": "UniProtKB", "id": "M9PHI0", "url": "https://www.uniprot.org/uniprotkb/M9PHI0" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "M9PHI0", "url": "https://www.uniprot.org/uniprotkb/M9PHI0" } ], "pmid": "" }, { "name": "alcohol dehydrogenase (NADP+) activity", "id": "GO:0008106", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008106", "evidence": [ { "database": "UniProtKB", "id": "M9PHI0", "url": "https://www.uniprot.org/uniprotkb/M9PHI0" } ], "pmid": "" }, { "name": "potassium channel activator activity", "id": "GO:0099104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099104", "evidence": [ { "database": "UniProtKB", "id": "M9PHI0", "url": "https://www.uniprot.org/uniprotkb/M9PHI0" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of circadian sleep/wake cycle, sleep", "id": "GO:0045938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045938", "evidence": [ { "database": "UniProtKB", "id": "M9PHI0", "url": "https://www.uniprot.org/uniprotkb/M9PHI0" } ], "pmid": "" }, { "name": "circadian sleep/wake cycle, sleep", "id": "GO:0050802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050802", "evidence": [ { "database": "UniProtKB", "id": "M9PHI0", "url": "https://www.uniprot.org/uniprotkb/M9PHI0" } ], "pmid": "" }, { "name": "regulation of potassium ion transmembrane transport", "id": "GO:1901379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901379", "evidence": [ { "database": "UniProtKB", "id": "M9PHI0", "url": "https://www.uniprot.org/uniprotkb/M9PHI0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PHI0-1", "start_pos": "200", "end_pos": "200", "site_lbl": "Thr200", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 200, "start_aa": "Thr", "end_pos": 200, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr200", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9PHI0-1" }, { "uniprot_canonical_ac": "M9PBJ1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PBJ1", "url": "https://www.uniprot.org/uniprotkb/M9PBJ1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 3664, "chemical_mass": 412844.0, "gene_names": "zormin;BcDNA:GH09541;CG11850;CG11952;CG11953;CG1282;CG32307;CG32309;CG32310;CG32311;CG33484;CG5699;CT36990;Dmel\\CG33484;Dmel_CG33484;Zormin;zormin", "protein_name": "", "disease": [], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "M9PBJ1", "url": "https://www.uniprot.org/uniprotkb/M9PBJ1" } ], "pmid": "" } ], "cellular_component": [ { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "M9PBJ1", "url": "https://www.uniprot.org/uniprotkb/M9PBJ1" } ], "pmid": "" }, { "name": "M band", "id": "GO:0031430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031430", "evidence": [ { "database": "UniProtKB", "id": "M9PBJ1", "url": "https://www.uniprot.org/uniprotkb/M9PBJ1" } ], "pmid": "" } ], "biological_process": [ { "name": "sarcomere organization", "id": "GO:0045214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045214", "evidence": [ { "database": "UniProtKB", "id": "M9PBJ1", "url": "https://www.uniprot.org/uniprotkb/M9PBJ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PBJ1-1", "start_pos": "2215", "end_pos": "2215", "site_lbl": "Thr2215", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2215, "start_aa": "Thr", "end_pos": 2215, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2215", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PBJ1-1", "start_pos": "2438", "end_pos": "2438", "site_lbl": "Thr2438", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 2438, "start_aa": "Thr", "end_pos": 2438, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2438", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "M9PBJ1", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=M9PBJ1" } ] } ] }, { "uniprot_canonical_ac": "M9PBJ1-1", "start_pos": "2641", "end_pos": "2641", "site_lbl": "Thr2641", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2641, "start_aa": "Thr", "end_pos": 2641, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2641", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PBJ1-1", "start_pos": "3012", "end_pos": "3012", "site_lbl": "Thr3012", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3012, "start_aa": "Thr", "end_pos": 3012, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3012", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PBJ1-1", "start_pos": "3014", "end_pos": "3014", "site_lbl": "Thr3014", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3014, "start_aa": "Thr", "end_pos": 3014, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3014", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PBJ1-1", "start_pos": "3195", "end_pos": "3195", "site_lbl": "Thr3195", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3195, "start_aa": "Thr", "end_pos": 3195, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3195", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PBJ1-1", "start_pos": "62", "end_pos": "62", "site_lbl": "Thr62", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 62, "start_aa": "Thr", "end_pos": 62, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr62", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9PBJ1-1" }, { "uniprot_canonical_ac": "Q9VPI3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPI3", "url": "https://www.uniprot.org/uniprotkb/Q9VPI3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1998, "chemical_mass": 221393.0, "gene_names": "Cda5;BcDNA:RH43162;CG2761;CG2776;CG31973;Cda5;DmCDA5;Dmel\\CG31973;Dmel_CG31973", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI3", "url": "https://www.uniprot.org/uniprotkb/Q9VPI3" } ], "pmid": "" } ], "biological_process": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI3", "url": "https://www.uniprot.org/uniprotkb/Q9VPI3" } ], "pmid": "" } ], "molecular_function": [ { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI3", "url": "https://www.uniprot.org/uniprotkb/Q9VPI3" } ], "pmid": "" }, { "name": "chitin deacetylase activity", "id": "GO:0004099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004099", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI3", "url": "https://www.uniprot.org/uniprotkb/Q9VPI3" } ], "pmid": "" }, { "name": "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds", "id": "GO:0016810", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016810", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI3", "url": "https://www.uniprot.org/uniprotkb/Q9VPI3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VPI3-1", "start_pos": "1470", "end_pos": "1470", "site_lbl": "Thr1470", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1470, "start_aa": "Thr", "end_pos": 1470, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1470", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VPI3-1", "start_pos": "337", "end_pos": "337", "site_lbl": "Thr337", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 337, "start_aa": "Thr", "end_pos": 337, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr337", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VPI3-1" }, { "uniprot_canonical_ac": "M9PG15-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1062, "chemical_mass": 116711.0, "gene_names": "SPoCk;2;ATP2C1/2;ATP2CD1;CG14449;CG32451;CG7651;Dmel\\CG32451;Dmel_CG32451;SPoCK;SPoCk;anon-WO0118547.249;sPoCk", "protein_name": "P-type Ca(2+) transporter", "disease": [ { "disease_id": "DOID:0050429", "name": "Hailey-Hailey disease", "description": "A pemphigus that is characterized by recurring blistering most commonly occurring in the folds of the skin, particularly the groin and axillary regions, and has_material_basis_in mutations in the ATP2C1 gene that result in loss of adhesion within the skin. Other sites of the body, such as the neck, perianal, and submammary regions, may likewise be affected.", "url": "https://disease-ontology.org/term/DOID:0050429", "evidence": [ { "id": "0050429", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050429" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "P-type calcium transporter activity", "id": "GO:0005388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005388", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "P-type manganese transporter activity", "id": "GO:0140613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140613", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular calcium ion homeostasis", "id": "GO:0006874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "peroxisomal membrane transport", "id": "GO:0015919", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015919", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "calcium ion transmembrane transport", "id": "GO:0070588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070588", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "manganese ion transport", "id": "GO:0006828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006828", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "calcium ion transport from cytosol to endoplasmic reticulum", "id": "GO:1903515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903515", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "Golgi calcium ion transmembrane transport", "id": "GO:0061856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061856", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" } ], "cellular_component": [ { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "sarcoplasmic reticulum membrane", "id": "GO:0033017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033017", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "peroxisomal membrane", "id": "GO:0005778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005778", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PG15-1", "start_pos": "685", "end_pos": "685", "site_lbl": "Thr685", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 685, "start_aa": "Thr", "end_pos": 685, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr685", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9PG15-1" }, { "uniprot_canonical_ac": "M9PFY3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PFY3", "url": "https://www.uniprot.org/uniprotkb/M9PFY3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1549, "chemical_mass": 166718.0, "gene_names": "CG33291;CG11250;CG33291;CG33292;CG43980;Dmel\\CG43980;Dmel_CG43980", "protein_name": "BTB domain-containing protein", "disease": [], "molecular_function": [ { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "M9PFY3", "url": "https://www.uniprot.org/uniprotkb/M9PFY3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PFY3-1", "start_pos": "1196", "end_pos": "1196", "site_lbl": "Thr1196", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1196, "start_aa": "Thr", "end_pos": 1196, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1196", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PFY3-1", "start_pos": "321", "end_pos": "321", "site_lbl": "Thr321", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 321, "start_aa": "Thr", "end_pos": 321, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr321", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PFY3-1", "start_pos": "422", "end_pos": "422", "site_lbl": "Thr422", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 422, "start_aa": "Thr", "end_pos": 422, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr422", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PFY3-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Thr80", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 80, "start_aa": "Thr", "end_pos": 80, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr80", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9PFY3-1" }, { "uniprot_canonical_ac": "Q8IQ43-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQ43", "url": "https://www.uniprot.org/uniprotkb/Q8IQ43" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 764, "chemical_mass": 87067.0, "gene_names": "Dmel\\CG11227;CG11227;Dmel\\CG11227;Dmel_CG11227", "protein_name": "DUF4729 domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IQ43-1" }, { "uniprot_canonical_ac": "M9PI51-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PI51", "url": "https://www.uniprot.org/uniprotkb/M9PI51" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 447, "chemical_mass": 48891.0, "gene_names": "Dmel\\CG10089;CG10089;Dmel\\CG10089;Dmel_CG10089", "protein_name": "Dual specificity protein phosphatase 15", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M9PI51", "url": "https://www.uniprot.org/uniprotkb/M9PI51" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "M9PI51", "url": "https://www.uniprot.org/uniprotkb/M9PI51" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "M9PI51", "url": "https://www.uniprot.org/uniprotkb/M9PI51" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "M9PI51", "url": "https://www.uniprot.org/uniprotkb/M9PI51" } ], "pmid": "" }, { "name": "protein tyrosine/serine/threonine phosphatase activity", "id": "GO:0008138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008138", "evidence": [ { "database": "UniProtKB", "id": "M9PI51", "url": "https://www.uniprot.org/uniprotkb/M9PI51" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "M9PI51", "url": "https://www.uniprot.org/uniprotkb/M9PI51" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PI51-1" }, { "uniprot_canonical_ac": "M9PC61-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PC61", "url": "https://www.uniprot.org/uniprotkb/M9PC61" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 606, "chemical_mass": 69811.0, "gene_names": "Dmel\\CG31664;CG15622;CG31664;Dmel_CG31664", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PC61-1" }, { "uniprot_canonical_ac": "Q8IQ73-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQ73", "url": "https://www.uniprot.org/uniprotkb/Q8IQ73" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1107, "chemical_mass": 121987.0, "gene_names": "corn;CG32386;CG32390;CG42278;CG8621;Corn;Dmel\\CG42278;Dmel_CG42278;corn", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ73", "url": "https://www.uniprot.org/uniprotkb/Q8IQ73" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ73", "url": "https://www.uniprot.org/uniprotkb/Q8IQ73" } ], "pmid": "" }, { "name": "apical part of cell", "id": "GO:0045177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045177", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ73", "url": "https://www.uniprot.org/uniprotkb/Q8IQ73" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ73", "url": "https://www.uniprot.org/uniprotkb/Q8IQ73" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ73", "url": "https://www.uniprot.org/uniprotkb/Q8IQ73" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of exocytosis", "id": "GO:0045921", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045921", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ73", "url": "https://www.uniprot.org/uniprotkb/Q8IQ73" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8IQ73-1", "start_pos": "158", "end_pos": "158", "site_lbl": "Thr158", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 158, "start_aa": "Thr", "end_pos": 158, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr158", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q8IQ73-1", "start_pos": "161", "end_pos": "161", "site_lbl": "Thr161", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 161, "start_aa": "Thr", "end_pos": 161, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr161", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q8IQ73-1" }, { "uniprot_canonical_ac": "Q9VDR5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDR5", "url": "https://www.uniprot.org/uniprotkb/Q9VDR5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 86, "chemical_mass": 9903.0, "gene_names": "Dmel\\CG4783;GH26202;CG4783;Dmel\\CG4783;Dmel_CG4783;GH26202", "protein_name": "Seminal fluid protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VDR5-1" }, { "uniprot_canonical_ac": "Q9VAV5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VAV5", "url": "https://www.uniprot.org/uniprotkb/Q9VAV5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 5080, "chemical_mass": 581089.0, "gene_names": "Dhc98D;CG1842;DHC6;DHC;Dhc98D;Dhc;Dmel\\CG1842;Dmel_CG1842;dhc", "protein_name": "", "disease": [ { "disease_id": "DOID:0060250", "name": "idiopathic scoliosis", "description": "A scoliosis with no known cause.", "url": "https://disease-ontology.org/term/DOID:0060250", "evidence": [ { "id": "0060250", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060250" } ], "weight": 0.0 }, { "disease_id": "DOID:0111910", "name": "spermatogenic failure", "description": "A male infertility characterized by disruption of the process of sperm development from diploid cells into mature haploid spermatozoa.", "url": "https://disease-ontology.org/term/DOID:0111910", "evidence": [ { "id": "0111910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111910" } ], "weight": 0.0 }, { "disease_id": "DOID:0112336", "name": "spermatogenic failure 56", "description": "A spermatogenic failure characterized by male infertility due to multiple morphologic abnormalities of the flagella with severely reduced sperm motility that has_material_basis_in homozygous or compound heterozygous mutation in the DNAH10 gene on chromosome 12q24.31.", "url": "https://disease-ontology.org/term/DOID:0112336", "evidence": [ { "id": "0112336", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112336" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cilium movement involved in cell motility", "id": "GO:0060294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060294", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV5", "url": "https://www.uniprot.org/uniprotkb/Q9VAV5" } ], "pmid": "" }, { "name": "inner dynein arm assembly", "id": "GO:0036159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036159", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV5", "url": "https://www.uniprot.org/uniprotkb/Q9VAV5" } ], "pmid": "" }, { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV5", "url": "https://www.uniprot.org/uniprotkb/Q9VAV5" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV5", "url": "https://www.uniprot.org/uniprotkb/Q9VAV5" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV5", "url": "https://www.uniprot.org/uniprotkb/Q9VAV5" } ], "pmid": "" }, { "name": "minus-end-directed microtubule motor activity", "id": "GO:0008569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008569", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV5", "url": "https://www.uniprot.org/uniprotkb/Q9VAV5" } ], "pmid": "" }, { "name": "dynein light intermediate chain binding", "id": "GO:0051959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051959", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV5", "url": "https://www.uniprot.org/uniprotkb/Q9VAV5" } ], "pmid": "" }, { "name": "dynein intermediate chain binding", "id": "GO:0045505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045505", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV5", "url": "https://www.uniprot.org/uniprotkb/Q9VAV5" } ], "pmid": "" } ], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV5", "url": "https://www.uniprot.org/uniprotkb/Q9VAV5" } ], "pmid": "" }, { "name": "inner dynein arm", "id": "GO:0036156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036156", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV5", "url": "https://www.uniprot.org/uniprotkb/Q9VAV5" } ], "pmid": "" }, { "name": "9+2 motile cilium", "id": "GO:0097729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097729", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV5", "url": "https://www.uniprot.org/uniprotkb/Q9VAV5" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV5", "url": "https://www.uniprot.org/uniprotkb/Q9VAV5" } ], "pmid": "" }, { "name": "dynein complex", "id": "GO:0030286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030286", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV5", "url": "https://www.uniprot.org/uniprotkb/Q9VAV5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VAV5-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Thr103", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 103, "start_aa": "Thr", "end_pos": 103, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr103", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VAV5-1", "start_pos": "2659", "end_pos": "2659", "site_lbl": "Thr2659", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2659, "start_aa": "Thr", "end_pos": 2659, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2659", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VAV5-1", "start_pos": "3205", "end_pos": "3205", "site_lbl": "Thr3205", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3205, "start_aa": "Thr", "end_pos": 3205, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3205", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VAV5-1" }, { "uniprot_canonical_ac": "Q9VMN3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VMN3", "url": "https://www.uniprot.org/uniprotkb/Q9VMN3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 438, "chemical_mass": 50410.0, "gene_names": "Cdkl;AC018104;CG7236/Cdk1l;CG7236;Cdk1l;Dmel\\CG7236;Dmel_CG7236;KKIALRE", "protein_name": "Cyclin-dependent kinase-like 2", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VMN3", "url": "https://www.uniprot.org/uniprotkb/Q9VMN3" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activity", "id": "GO:0004693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004693", "evidence": [ { "database": "UniProtKB", "id": "Q9VMN3", "url": "https://www.uniprot.org/uniprotkb/Q9VMN3" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "Q9VMN3", "url": "https://www.uniprot.org/uniprotkb/Q9VMN3" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "Q9VMN3", "url": "https://www.uniprot.org/uniprotkb/Q9VMN3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VMN3", "url": "https://www.uniprot.org/uniprotkb/Q9VMN3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VMN3", "url": "https://www.uniprot.org/uniprotkb/Q9VMN3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VMN3-1" }, { "uniprot_canonical_ac": "Q7KTA9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KTA9", "url": "https://www.uniprot.org/uniprotkb/Q7KTA9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 626, "chemical_mass": 68800.0, "gene_names": "Gpo3;BG:DS08249.2;CG7311;Dmel\\CG7311;Dmel_CG7311;GPO-3;GPO;Gpo3;Gpo;alpha-GPO;gpo-3", "protein_name": "Glycerol-3-phosphate dehydrogenase", "disease": [], "molecular_function": [ { "name": "glycerol-3-phosphate dehydrogenase (quinone) activity", "id": "GO:0004368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004368", "evidence": [ { "database": "UniProtKB", "id": "Q7KTA9", "url": "https://www.uniprot.org/uniprotkb/Q7KTA9" } ], "pmid": "" } ], "biological_process": [ { "name": "glycerol-3-phosphate metabolic process", "id": "GO:0006072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006072", "evidence": [ { "database": "UniProtKB", "id": "Q7KTA9", "url": "https://www.uniprot.org/uniprotkb/Q7KTA9" } ], "pmid": "" }, { "name": "glycerol-3-phosphate shuttle", "id": "GO:0006127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006127", "evidence": [ { "database": "UniProtKB", "id": "Q7KTA9", "url": "https://www.uniprot.org/uniprotkb/Q7KTA9" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q7KTA9", "url": "https://www.uniprot.org/uniprotkb/Q7KTA9" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q7KTA9", "url": "https://www.uniprot.org/uniprotkb/Q7KTA9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7KTA9-1", "start_pos": "313", "end_pos": "313", "site_lbl": "Thr313", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 313, "start_aa": "Thr", "end_pos": 313, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr313", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q7KTA9-1" }, { "uniprot_canonical_ac": "Q9VJ99-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VJ99", "url": "https://www.uniprot.org/uniprotkb/Q9VJ99" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 258, "chemical_mass": 29717.0, "gene_names": "CT35055;Dmel\\CG15155;CG15155;CT35055;Dmel\\CG15155;Dmel_CG15155", "protein_name": "GCN5-related N-acetyltransferase Rv2170-like domain-containing protein", "disease": [], "molecular_function": [ { "name": "acyltransferase activity, transferring groups other than amino-acyl groups", "id": "GO:0016747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016747", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ99", "url": "https://www.uniprot.org/uniprotkb/Q9VJ99" } ], "pmid": "" }, { "name": "glycine N-acyltransferase activity", "id": "GO:0047961", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047961", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ99", "url": "https://www.uniprot.org/uniprotkb/Q9VJ99" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VJ99-1" }, { "uniprot_canonical_ac": "M9PE53-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1069, "chemical_mass": 116706.0, "gene_names": "mwh;BP1018;CG13913;CG34022;CG43772;Dmel\\CG43772;Dmel_CG43772;Mwh;mwh", "protein_name": "", "disease": [], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "pmid": "" } ], "biological_process": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "pmid": "" }, { "name": "regulation of cell morphogenesis", "id": "GO:0022604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022604", "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "pmid": "" }, { "name": "negative regulation of actin filament polymerization", "id": "GO:0030837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030837", "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "pmid": "" }, { "name": "establishment of planar polarity", "id": "GO:0001736", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001736", "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "pmid": "" }, { "name": "imaginal disc-derived wing hair site selection", "id": "GO:0035320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035320", "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "pmid": "" }, { "name": "imaginal disc-derived wing morphogenesis", "id": "GO:0007476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007476", "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "pmid": "" }, { "name": "imaginal disc-derived wing hair organization", "id": "GO:0035317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035317", "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton organization", "id": "GO:0030866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030866", "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PE53-1", "start_pos": "949", "end_pos": "949", "site_lbl": "Thr949", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 949, "start_aa": "Thr", "end_pos": 949, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr949", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9PE53-1" }, { "uniprot_canonical_ac": "Q9VMY0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VMY0", "url": "https://www.uniprot.org/uniprotkb/Q9VMY0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 319, "chemical_mass": 36069.0, "gene_names": "jet;CG8873;Dmel\\CG8873;Dmel_CG8873;FBXL15;JETLAG;JET;Jet;jet", "protein_name": "", "disease": [], "cellular_component": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "Q9VMY0", "url": "https://www.uniprot.org/uniprotkb/Q9VMY0" } ], "pmid": "" } ], "biological_process": [ { "name": "locomotor rhythm", "id": "GO:0045475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045475", "evidence": [ { "database": "UniProtKB", "id": "Q9VMY0", "url": "https://www.uniprot.org/uniprotkb/Q9VMY0" } ], "pmid": "" }, { "name": "entrainment of circadian clock by photoperiod", "id": "GO:0043153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043153", "evidence": [ { "database": "UniProtKB", "id": "Q9VMY0", "url": "https://www.uniprot.org/uniprotkb/Q9VMY0" } ], "pmid": "" }, { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "Q9VMY0", "url": "https://www.uniprot.org/uniprotkb/Q9VMY0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VMY0-1" }, { "uniprot_canonical_ac": "Q86B99-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q86B99", "url": "https://www.uniprot.org/uniprotkb/Q86B99" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 893, "chemical_mass": 98063.0, "gene_names": "CG18546;CG14732;CG18546;CG31211;Dmel\\CG31211;Dmel_CG31211;anon-WO03070958.3;cDNA", "protein_name": "Arginine/serine-rich protein PNISR", "disease": [], "cellular_component": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q86B99", "url": "https://www.uniprot.org/uniprotkb/Q86B99" } ], "pmid": "" }, { "name": "presynaptic active zone", "id": "GO:0048786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048786", "evidence": [ { "database": "UniProtKB", "id": "Q86B99", "url": "https://www.uniprot.org/uniprotkb/Q86B99" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q86B99", "url": "https://www.uniprot.org/uniprotkb/Q86B99" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q86B99-1" }, { "uniprot_canonical_ac": "Q59E43-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q59E43", "url": "https://www.uniprot.org/uniprotkb/Q59E43" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 140, "chemical_mass": 15273.0, "gene_names": "Dmel\\CG32576;anon-AE003501.1;BcDNA:RE29988;CG32576;Dmel\\CG32576;Dmel_CG32576;NEST:bs01h05;anon-AE003501.1", "protein_name": "Vesicle transport protein GOT1B", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q59E43", "url": "https://www.uniprot.org/uniprotkb/Q59E43" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q59E43", "url": "https://www.uniprot.org/uniprotkb/Q59E43" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q59E43", "url": "https://www.uniprot.org/uniprotkb/Q59E43" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q59E43", "url": "https://www.uniprot.org/uniprotkb/Q59E43" } ], "pmid": "" } ], "biological_process": [ { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "Q59E43", "url": "https://www.uniprot.org/uniprotkb/Q59E43" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "Q59E43", "url": "https://www.uniprot.org/uniprotkb/Q59E43" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q59E43-1" }, { "uniprot_canonical_ac": "Q9VFI0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VFI0", "url": "https://www.uniprot.org/uniprotkb/Q9VFI0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1220, "chemical_mass": 135807.0, "gene_names": "stumps;0837/10;10;CG18485;CG31317;CG3375;C;DOF;Dmel\\CG31317;Dmel_CG31317;Dof/stumps/heartbroken;Dof;Hbr/Dof;Hbr;P1740;Stumps;anon-EST:CL47;anon-estC;dof/hbr/sms;dof/hbr;dof1;dof;gene C;hbr;heartbroken/dof;heartbroken;i21;i28;l(3)09904;l(3)S083710;sms;stumps/dof;stumps", "protein_name": "", "disease": [ { "disease_id": "DOID:1580", "name": "diffuse scleroderma", "description": "", "url": "https://disease-ontology.org/term/DOID:1580", "evidence": [ { "id": "1580", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1580" } ], "weight": 0.0 }, { "disease_id": "DOID:418", "name": "systemic scleroderma", "description": "A scleroderma that is characterized by fibrosis (or hardening) of the skin and major organs, as well as vascular alterations, and autoantibodies.", "url": "https://disease-ontology.org/term/DOID:418", "evidence": [ { "id": "418", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:418" } ], "weight": 0.0 }, { "disease_id": "DOID:7188", "name": "autoimmune thyroiditis", "description": "An autoimmune disease of endocrine system that involves inflammation located_in thyroid gland caused by the immune system reacting against its own tissues.", "url": "https://disease-ontology.org/term/DOID:7188", "evidence": [ { "id": "7188", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7188" } ], "weight": 0.0 }, { "disease_id": "DOID:8893", "name": "psoriasis", "description": "A skin disease that is characterized by patches of thick red skin and silvery scales.", "url": "https://disease-ontology.org/term/DOID:8893", "evidence": [ { "id": "8893", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8893" } ], "weight": 0.0 }, { "disease_id": "DOID:9074", "name": "systemic lupus erythematosus", "description": "A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.", "url": "https://disease-ontology.org/term/DOID:9074", "evidence": [ { "id": "9074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9074" } ], "weight": 0.0 }, { "disease_id": "DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.", "url": "https://disease-ontology.org/term/DOID:9744", "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ], "weight": 0.0 } ], "biological_process": [ { "name": "glial cell development", "id": "GO:0021782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021782", "evidence": [ { "database": "UniProtKB", "id": "Q9VFI0", "url": "https://www.uniprot.org/uniprotkb/Q9VFI0" } ], "pmid": "" }, { "name": "mesodermal cell migration", "id": "GO:0008078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008078", "evidence": [ { "database": "UniProtKB", "id": "Q9VFI0", "url": "https://www.uniprot.org/uniprotkb/Q9VFI0" } ], "pmid": "" }, { "name": "mesoderm development", "id": "GO:0007498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007498", "evidence": [ { "database": "UniProtKB", "id": "Q9VFI0", "url": "https://www.uniprot.org/uniprotkb/Q9VFI0" } ], "pmid": "" }, { "name": "open tracheal system development", "id": "GO:0007424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007424", "evidence": [ { "database": "UniProtKB", "id": "Q9VFI0", "url": "https://www.uniprot.org/uniprotkb/Q9VFI0" } ], "pmid": "" }, { "name": "mesodermal cell fate commitment", "id": "GO:0001710", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001710", "evidence": [ { "database": "UniProtKB", "id": "Q9VFI0", "url": "https://www.uniprot.org/uniprotkb/Q9VFI0" } ], "pmid": "" }, { "name": "fibroblast growth factor receptor signaling pathway", "id": "GO:0008543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008543", "evidence": [ { "database": "UniProtKB", "id": "Q9VFI0", "url": "https://www.uniprot.org/uniprotkb/Q9VFI0" } ], "pmid": "" }, { "name": "tracheal outgrowth, open tracheal system", "id": "GO:0007426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007426", "evidence": [ { "database": "UniProtKB", "id": "Q9VFI0", "url": "https://www.uniprot.org/uniprotkb/Q9VFI0" } ], "pmid": "" }, { "name": "epithelial cell migration, open tracheal system", "id": "GO:0007427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007427", "evidence": [ { "database": "UniProtKB", "id": "Q9VFI0", "url": "https://www.uniprot.org/uniprotkb/Q9VFI0" } ], "pmid": "" }, { "name": "epithelial cell fate determination, open tracheal system", "id": "GO:0007425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007425", "evidence": [ { "database": "UniProtKB", "id": "Q9VFI0", "url": "https://www.uniprot.org/uniprotkb/Q9VFI0" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VFI0", "url": "https://www.uniprot.org/uniprotkb/Q9VFI0" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane receptor protein tyrosine kinase adaptor activity", "id": "GO:0005068", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005068", "evidence": [ { "database": "UniProtKB", "id": "Q9VFI0", "url": "https://www.uniprot.org/uniprotkb/Q9VFI0" } ], "pmid": "" }, { "name": "fibroblast growth factor receptor binding", "id": "GO:0005104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005104", "evidence": [ { "database": "UniProtKB", "id": "Q9VFI0", "url": "https://www.uniprot.org/uniprotkb/Q9VFI0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VFI0-1", "start_pos": "1057", "end_pos": "1057", "site_lbl": "Thr1057", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1057, "start_aa": "Thr", "end_pos": 1057, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1057", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VFI0-1", "start_pos": "1067", "end_pos": "1067", "site_lbl": "Thr1067", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1067, "start_aa": "Thr", "end_pos": 1067, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1067", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VFI0-1" }, { "uniprot_canonical_ac": "Q8MLX0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8MLX0", "url": "https://www.uniprot.org/uniprotkb/Q8MLX0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1161, "chemical_mass": 130934.0, "gene_names": "Dmel\\CG3216;CG3216;Dmel\\CG3216;Dmel_CG3216;GYC", "protein_name": "Guanylate cyclase", "disease": [ { "disease_id": "DOID:0070316", "name": "Miura type epiphyseal chondrodysplasia", "description": "A bone developmental disease characterized by tall stature, scoliosis and macrodactyly of the great toes that has_material_basis_in heterozygous mutation in the NPR2 gene on chromosome 9p13.", "url": "https://disease-ontology.org/term/DOID:0070316", "evidence": [ { "id": "0070316", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070316" } ], "weight": 0.0 }, { "disease_id": "DOID:0080006", "name": "bone development disease", "description": "A bone disease that results_in abnormal growth and development located_in bone or located_in cartilage.", "url": "https://disease-ontology.org/term/DOID:0080006", "evidence": [ { "id": "0080006", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080006" } ], "weight": 0.0 }, { "disease_id": "DOID:0080050", "name": "acromesomelic dysplasia, Maroteaux type", "description": "An acromesomelic dysplasia that has_material_basis_in homozygous or compound heterozygous mutation in the NPR2 gene, which encodes natriuretic peptide receptor B, on chromosome 9p13.", "url": "https://disease-ontology.org/term/DOID:0080050", "evidence": [ { "id": "0080050", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080050" } ], "weight": 0.0 }, { "disease_id": "DOID:10825", "name": "essential hypertension", "description": "A hypertension with no known cause. It is the most common type of hypertension.", "url": "https://disease-ontology.org/term/DOID:10825", "evidence": [ { "id": "10825", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10825" } ], "weight": 0.0 }, { "disease_id": "DOID:4480", "name": "achondroplasia", "description": "An osteochondrodysplasia that is characterized by short stature caused by rhizomelic shortening of the limbs, characteristic facies with frontal bossing and midface hypoplasia, exaggerated lumbar lordosis, limitation of elbow extension, genu varum, and trident hand and that has_material_basis_in heterozygous mutation in the fibroblast growth factor receptor-3 gene (FGFR3) on chromosome 4p16.3. Achondroplasia results in dwarfism due to the abnormal ossification of cartilage in the long bone.", "url": "https://disease-ontology.org/term/DOID:4480", "evidence": [ { "id": "4480", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4480" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "guanylate cyclase activity", "id": "GO:0004383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004383", "evidence": [ { "database": "UniProtKB", "id": "Q8MLX0", "url": "https://www.uniprot.org/uniprotkb/Q8MLX0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q8MLX0", "url": "https://www.uniprot.org/uniprotkb/Q8MLX0" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q8MLX0", "url": "https://www.uniprot.org/uniprotkb/Q8MLX0" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "Q8MLX0", "url": "https://www.uniprot.org/uniprotkb/Q8MLX0" } ], "pmid": "" }, { "name": "peptide receptor activity", "id": "GO:0001653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001653", "evidence": [ { "database": "UniProtKB", "id": "Q8MLX0", "url": "https://www.uniprot.org/uniprotkb/Q8MLX0" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q8MLX0", "url": "https://www.uniprot.org/uniprotkb/Q8MLX0" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "Q8MLX0", "url": "https://www.uniprot.org/uniprotkb/Q8MLX0" } ], "pmid": "" }, { "name": "cGMP biosynthetic process", "id": "GO:0006182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006182", "evidence": [ { "database": "UniProtKB", "id": "Q8MLX0", "url": "https://www.uniprot.org/uniprotkb/Q8MLX0" } ], "pmid": "" }, { "name": "receptor guanylyl cyclase signaling pathway", "id": "GO:0007168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007168", "evidence": [ { "database": "UniProtKB", "id": "Q8MLX0", "url": "https://www.uniprot.org/uniprotkb/Q8MLX0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8MLX0-1" }, { "uniprot_canonical_ac": "Q9VK51-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VK51", "url": "https://www.uniprot.org/uniprotkb/Q9VK51" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1112, "chemical_mass": 127938.0, "gene_names": "ACXA;AC62D;ACXA;AC;Ac62D;CG17176;DACXA;Dmel\\CG17176;Dmel_CG17176", "protein_name": "adenylate cyclase", "disease": [ { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:3312", "name": "bipolar disorder", "description": "A mood disorder that involves alternating periods of mania and depression.", "url": "https://disease-ontology.org/term/DOID:3312", "evidence": [ { "id": "3312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3312" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "adenylate cyclase activity", "id": "GO:0004016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004016", "evidence": [ { "database": "UniProtKB", "id": "Q9VK51", "url": "https://www.uniprot.org/uniprotkb/Q9VK51" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VK51", "url": "https://www.uniprot.org/uniprotkb/Q9VK51" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VK51", "url": "https://www.uniprot.org/uniprotkb/Q9VK51" } ], "pmid": "" } ], "biological_process": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "Q9VK51", "url": "https://www.uniprot.org/uniprotkb/Q9VK51" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "Q9VK51", "url": "https://www.uniprot.org/uniprotkb/Q9VK51" } ], "pmid": "" }, { "name": "cyclic nucleotide biosynthetic process", "id": "GO:0009190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009190", "evidence": [ { "database": "UniProtKB", "id": "Q9VK51", "url": "https://www.uniprot.org/uniprotkb/Q9VK51" } ], "pmid": "" }, { "name": "cAMP biosynthetic process", "id": "GO:0006171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006171", "evidence": [ { "database": "UniProtKB", "id": "Q9VK51", "url": "https://www.uniprot.org/uniprotkb/Q9VK51" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "Q9VK51", "url": "https://www.uniprot.org/uniprotkb/Q9VK51" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VK51", "url": "https://www.uniprot.org/uniprotkb/Q9VK51" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VK51", "url": "https://www.uniprot.org/uniprotkb/Q9VK51" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VK51-1" }, { "uniprot_canonical_ac": "Q4ABI9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q4ABI9", "url": "https://www.uniprot.org/uniprotkb/Q4ABI9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 181, "chemical_mass": 20947.0, "gene_names": "Dmel\\CG33725;CG33725;Dmel\\CG33725;Dmel_CG33725", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q4ABI9-1" }, { "uniprot_canonical_ac": "Q8IMT8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 246, "chemical_mass": 27585.0, "gene_names": "veli;CG7662;D-veli;DLin-7;DLin7;Dmel\\CG7662;Dmel_CG7662;Dveli;Flin-7;LIN7;Lin-7;Lin7;Veli;d-Veli;dLin-7;dLin7;dVeli;lin-7;lin7;veli", "protein_name": "Protein lin-7 homolog", "disease": [], "cellular_component": [ { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" }, { "name": "subapical complex", "id": "GO:0035003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035003", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" }, { "name": "MPP7-DLG1-LIN7 complex", "id": "GO:0097025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097025", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" }, { "name": "neurotransmitter secretion", "id": "GO:0007269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007269", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" }, { "name": "regulation of synaptic assembly at neuromuscular junction", "id": "GO:0008582", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008582", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" }, { "name": "border follicle cell migration", "id": "GO:0007298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007298", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" }, { "name": "synaptic vesicle transport", "id": "GO:0048489", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048489", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IMT8-1" }, { "uniprot_canonical_ac": "Q0KI93-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0KI93", "url": "https://www.uniprot.org/uniprotkb/Q0KI93" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 630, "chemical_mass": 67470.0, "gene_names": "Whamy;CG12946;Dmel\\CG12946;Dmel_CG12946;Whamy;whamy", "protein_name": "", "disease": [], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "Q0KI93", "url": "https://www.uniprot.org/uniprotkb/Q0KI93" } ], "pmid": "" }, { "name": "GTPase binding", "id": "GO:0051020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051020", "evidence": [ { "database": "UniProtKB", "id": "Q0KI93", "url": "https://www.uniprot.org/uniprotkb/Q0KI93" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "Q0KI93", "url": "https://www.uniprot.org/uniprotkb/Q0KI93" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q0KI93", "url": "https://www.uniprot.org/uniprotkb/Q0KI93" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "Q0KI93", "url": "https://www.uniprot.org/uniprotkb/Q0KI93" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "Q0KI93", "url": "https://www.uniprot.org/uniprotkb/Q0KI93" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q0KI93", "url": "https://www.uniprot.org/uniprotkb/Q0KI93" } ], "pmid": "" } ], "biological_process": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "Q0KI93", "url": "https://www.uniprot.org/uniprotkb/Q0KI93" } ], "pmid": "" }, { "name": "myoblast fusion", "id": "GO:0007520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007520", "evidence": [ { "database": "UniProtKB", "id": "Q0KI93", "url": "https://www.uniprot.org/uniprotkb/Q0KI93" } ], "pmid": "" }, { "name": "positive regulation of actin nucleation", "id": "GO:0051127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051127", "evidence": [ { "database": "UniProtKB", "id": "Q0KI93", "url": "https://www.uniprot.org/uniprotkb/Q0KI93" } ], "pmid": "" }, { "name": "positive regulation of actin filament polymerization", "id": "GO:0030838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030838", "evidence": [ { "database": "UniProtKB", "id": "Q0KI93", "url": "https://www.uniprot.org/uniprotkb/Q0KI93" } ], "pmid": "" }, { "name": "microtubule bundle formation", "id": "GO:0001578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001578", "evidence": [ { "database": "UniProtKB", "id": "Q0KI93", "url": "https://www.uniprot.org/uniprotkb/Q0KI93" } ], "pmid": "" }, { "name": "regulation of actin filament polymerization", "id": "GO:0030833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030833", "evidence": [ { "database": "UniProtKB", "id": "Q0KI93", "url": "https://www.uniprot.org/uniprotkb/Q0KI93" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q0KI93-1", "start_pos": "289", "end_pos": "289", "site_lbl": "Thr289", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 289, "start_aa": "Thr", "end_pos": 289, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr289", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q0KI93-1", "start_pos": "333", "end_pos": "333", "site_lbl": "Thr333", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 333, "start_aa": "Thr", "end_pos": 333, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr333", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q0KI93-1", "start_pos": "492", "end_pos": "492", "site_lbl": "Thr492", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 492, "start_aa": "Thr", "end_pos": 492, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr492", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q0KI93-1" }, { "uniprot_canonical_ac": "Q9VAC9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VAC9", "url": "https://www.uniprot.org/uniprotkb/Q9VAC9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 384, "chemical_mass": 40233.0, "gene_names": "cg7903;CG7903;Dmel\\CG7903;Dmel_CG7903;cg7903", "protein_name": "RRM domain-containing protein", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q9VAC9", "url": "https://www.uniprot.org/uniprotkb/Q9VAC9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VAC9-1" }, { "uniprot_canonical_ac": "Q8IMH9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IMH9", "url": "https://www.uniprot.org/uniprotkb/Q8IMH9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 659, "chemical_mass": 74277.0, "gene_names": "Dmel\\CG31019;CG31019;Dmel\\CG31019;Dmel_CG31019", "protein_name": "Peptidase M14 domain-containing protein", "disease": [], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q8IMH9", "url": "https://www.uniprot.org/uniprotkb/Q8IMH9" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q8IMH9", "url": "https://www.uniprot.org/uniprotkb/Q8IMH9" } ], "pmid": "" }, { "name": "metallocarboxypeptidase activity", "id": "GO:0004181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004181", "evidence": [ { "database": "UniProtKB", "id": "Q8IMH9", "url": "https://www.uniprot.org/uniprotkb/Q8IMH9" } ], "pmid": "" }, { "name": "tubulin binding", "id": "GO:0015631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015631", "evidence": [ { "database": "UniProtKB", "id": "Q8IMH9", "url": "https://www.uniprot.org/uniprotkb/Q8IMH9" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q8IMH9", "url": "https://www.uniprot.org/uniprotkb/Q8IMH9" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "Q8IMH9", "url": "https://www.uniprot.org/uniprotkb/Q8IMH9" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "Q8IMH9", "url": "https://www.uniprot.org/uniprotkb/Q8IMH9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IMH9-1" }, { "uniprot_canonical_ac": "Q8INN6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8INN6", "url": "https://www.uniprot.org/uniprotkb/Q8INN6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 784, "chemical_mass": 86261.0, "gene_names": "Unc-115b;CG31332;CG9489;Dmel\\CG31332;Dmel_CG31332;Unc-115a;Unc-115b;anon-WO0140519.9;unc-115", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q8INN6", "url": "https://www.uniprot.org/uniprotkb/Q8INN6" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "Q8INN6", "url": "https://www.uniprot.org/uniprotkb/Q8INN6" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q8INN6", "url": "https://www.uniprot.org/uniprotkb/Q8INN6" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "Q8INN6", "url": "https://www.uniprot.org/uniprotkb/Q8INN6" } ], "pmid": "" } ], "biological_process": [ { "name": "lamellipodium assembly", "id": "GO:0030032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030032", "evidence": [ { "database": "UniProtKB", "id": "Q8INN6", "url": "https://www.uniprot.org/uniprotkb/Q8INN6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8INN6-1" }, { "uniprot_canonical_ac": "Q59E63-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q59E63", "url": "https://www.uniprot.org/uniprotkb/Q59E63" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 396, "chemical_mass": 44685.0, "gene_names": "Dmel\\CG11406;CG11406;Dmel\\CG11406;Dmel_CG11406", "protein_name": "Lipase", "disease": [ { "disease_id": "DOID:0080217", "name": "lysosomal acid lipase deficiency", "description": "A lipid storage disease characterized by dyslipidemia and accumulation of cholesteryl esters and triglycerides within various organs that has_material_basis_in homozygous or compound heterozygous mutation in the LIPA gene on chromosome 10q23.31.", "url": "https://disease-ontology.org/term/DOID:0080217", "evidence": [ { "id": "0080217", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080217" } ], "weight": 0.0 }, { "disease_id": "DOID:14497", "name": "Wolman disease", "description": "A lysosomal acid lipase deficiency characterized by infantile onset of rapidly progressive accumulation of cholesteryl esters and triglycerides throughout the body, resulting in hepatosplenomegaly, severe malnutrition, jaundice, vomiting, diarrhea, steatorrhea. Death usually occurs within the first year of life.", "url": "https://disease-ontology.org/term/DOID:14497", "evidence": [ { "id": "14497", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14497" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q59E63", "url": "https://www.uniprot.org/uniprotkb/Q59E63" } ], "pmid": "" }, { "name": "lipase activity", "id": "GO:0016298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016298", "evidence": [ { "database": "UniProtKB", "id": "Q59E63", "url": "https://www.uniprot.org/uniprotkb/Q59E63" } ], "pmid": "" }, { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "Q59E63", "url": "https://www.uniprot.org/uniprotkb/Q59E63" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "Q59E63", "url": "https://www.uniprot.org/uniprotkb/Q59E63" } ], "pmid": "" }, { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "Q59E63", "url": "https://www.uniprot.org/uniprotkb/Q59E63" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q59E63-1" }, { "uniprot_canonical_ac": "Q0E8Q7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0E8Q7", "url": "https://www.uniprot.org/uniprotkb/Q0E8Q7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1597, "chemical_mass": 182701.0, "gene_names": "Eato;BG:DS00797.5;CG31731;CG7491;CG7559;D00797.5;DS00797.5;DmCG31731;Dmel\\CG31731;Dmel_CG31731;Eato", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q0E8Q7", "url": "https://www.uniprot.org/uniprotkb/Q0E8Q7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q0E8Q7", "url": "https://www.uniprot.org/uniprotkb/Q0E8Q7" } ], "pmid": "" } ], "molecular_function": [ { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "Q0E8Q7", "url": "https://www.uniprot.org/uniprotkb/Q0E8Q7" } ], "pmid": "" }, { "name": "lipid transporter activity", "id": "GO:0005319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005319", "evidence": [ { "database": "UniProtKB", "id": "Q0E8Q7", "url": "https://www.uniprot.org/uniprotkb/Q0E8Q7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q0E8Q7", "url": "https://www.uniprot.org/uniprotkb/Q0E8Q7" } ], "pmid": "" }, { "name": "ATPase-coupled transmembrane transporter activity", "id": "GO:0042626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042626", "evidence": [ { "database": "UniProtKB", "id": "Q0E8Q7", "url": "https://www.uniprot.org/uniprotkb/Q0E8Q7" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q0E8Q7", "url": "https://www.uniprot.org/uniprotkb/Q0E8Q7" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "Q0E8Q7", "url": "https://www.uniprot.org/uniprotkb/Q0E8Q7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q0E8Q7-1" }, { "uniprot_canonical_ac": "Q9VKT4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VKT4", "url": "https://www.uniprot.org/uniprotkb/Q9VKT4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 409, "chemical_mass": 46997.0, "gene_names": "w-cup;BcDNA:AT31112;CG7363;Dmel\\CG7363;Dmel_CG7363;w-cup", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VKT4-1" }, { "uniprot_canonical_ac": "M9NFY9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NFY9", "url": "https://www.uniprot.org/uniprotkb/M9NFY9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 169, "chemical_mass": 19795.0, "gene_names": "Dmel\\CG43090;CG43090;Dmel\\CG43090;Dmel_CG43090", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9NFY9-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Thr124", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 124, "start_aa": "Thr", "end_pos": 124, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr124", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "M9NFY9", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=M9NFY9" } ] } ] } ], "record_id": "M9NFY9-1" }, { "uniprot_canonical_ac": "M9NGE9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NGE9", "url": "https://www.uniprot.org/uniprotkb/M9NGE9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 362, "chemical_mass": 41401.0, "gene_names": "MB8.chrX.pasa.104-MIP02663;CG43088;Dmel\\CG43088;Dmel_CG43088;MB8.chrX.pasa.104-MIP02663;MB8.chrX.pasa.104", "protein_name": "DDE Tnp4 domain-containing protein", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9NGE9", "url": "https://www.uniprot.org/uniprotkb/M9NGE9" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "M9NGE9", "url": "https://www.uniprot.org/uniprotkb/M9NGE9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "M9NGE9", "url": "https://www.uniprot.org/uniprotkb/M9NGE9" } ], "pmid": "" }, { "name": "nuclease activity", "id": "GO:0004518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004518", "evidence": [ { "database": "UniProtKB", "id": "M9NGE9", "url": "https://www.uniprot.org/uniprotkb/M9NGE9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9NGE9-1" }, { "uniprot_canonical_ac": "M9PBD0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PBD0", "url": "https://www.uniprot.org/uniprotkb/M9PBD0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 35, "chemical_mass": 3870.0, "gene_names": "Dmel\\CG43220;CG43220;DMG8-chr2L.31.003;Dmel\\CG43220;Dmel_CG43220", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PBD0-1" }, { "uniprot_canonical_ac": "M9PBI0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PBI0", "url": "https://www.uniprot.org/uniprotkb/M9PBI0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 182, "chemical_mass": 21187.0, "gene_names": "Dmel\\CG32313;CG32313;Dmel\\CG32313;Dmel_CG32313", "protein_name": "SCP domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "M9PBI0", "url": "https://www.uniprot.org/uniprotkb/M9PBI0" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "M9PBI0", "url": "https://www.uniprot.org/uniprotkb/M9PBI0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PBI0-1" }, { "uniprot_canonical_ac": "M9PBM5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PBM5", "url": "https://www.uniprot.org/uniprotkb/M9PBM5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 682, "chemical_mass": 77542.0, "gene_names": "NEST:bs23f04;BcDNA:GH10778;CG31920;CG33992;CG43755;Dmel\\CG43755;Dmel_CG43755;NEST:bs21f09;NEST:bs23f04;anon-WO0140519.62", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PBM5-1", "start_pos": "420", "end_pos": "420", "site_lbl": "Ser420", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 420, "start_aa": "Ser", "end_pos": 420, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser420", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "M9PBM5", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=M9PBM5" } ] } ] } ], "record_id": "M9PBM5-1" }, { "uniprot_canonical_ac": "M9PBV9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PBV9", "url": "https://www.uniprot.org/uniprotkb/M9PBV9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 71, "chemical_mass": 8580.0, "gene_names": "Dmel\\CG43886;CG43886;Dmel\\CG43886;Dmel_CG43886;lincRNA.469", "protein_name": "Rod shape-determining protein MreD", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PBV9-1" }, { "uniprot_canonical_ac": "M9PCF9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PCF9", "url": "https://www.uniprot.org/uniprotkb/M9PCF9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 646, "chemical_mass": 70350.0, "gene_names": "Dmel\\CG9541;CG9541;Dmel\\CG9541;Dmel_CG9541", "protein_name": "Adenylate kinase isoenzyme 5", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "M9PCF9", "url": "https://www.uniprot.org/uniprotkb/M9PCF9" } ], "pmid": "" }, { "name": "UMP kinase activity", "id": "GO:0033862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033862", "evidence": [ { "database": "UniProtKB", "id": "M9PCF9", "url": "https://www.uniprot.org/uniprotkb/M9PCF9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PCF9", "url": "https://www.uniprot.org/uniprotkb/M9PCF9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9PCF9", "url": "https://www.uniprot.org/uniprotkb/M9PCF9" } ], "pmid": "" } ], "biological_process": [ { "name": "UDP biosynthetic process", "id": "GO:0006225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006225", "evidence": [ { "database": "UniProtKB", "id": "M9PCF9", "url": "https://www.uniprot.org/uniprotkb/M9PCF9" } ], "pmid": "" }, { "name": "CDP biosynthetic process", "id": "GO:0046705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046705", "evidence": [ { "database": "UniProtKB", "id": "M9PCF9", "url": "https://www.uniprot.org/uniprotkb/M9PCF9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PCF9-1" }, { "uniprot_canonical_ac": "M9PCG2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PCG2", "url": "https://www.uniprot.org/uniprotkb/M9PCG2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 587, "chemical_mass": 62565.0, "gene_names": "Sox21b;CG13483;CG32139;CG6419;Dmel\\CG32139;Dmel_CG32139;SOXB2.2;Sox B2-2;Sox21B;Sox21b;SoxB2.2", "protein_name": "", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "M9PCG2", "url": "https://www.uniprot.org/uniprotkb/M9PCG2" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "M9PCG2", "url": "https://www.uniprot.org/uniprotkb/M9PCG2" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "M9PCG2", "url": "https://www.uniprot.org/uniprotkb/M9PCG2" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "M9PCG2", "url": "https://www.uniprot.org/uniprotkb/M9PCG2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PCG2", "url": "https://www.uniprot.org/uniprotkb/M9PCG2" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "M9PCG2", "url": "https://www.uniprot.org/uniprotkb/M9PCG2" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "M9PCG2", "url": "https://www.uniprot.org/uniprotkb/M9PCG2" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "M9PCG2", "url": "https://www.uniprot.org/uniprotkb/M9PCG2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PCG2-1", "start_pos": "350", "end_pos": "350", "site_lbl": "Thr350", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 350, "start_aa": "Thr", "end_pos": 350, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr350", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PCG2-1", "start_pos": "359", "end_pos": "359", "site_lbl": "Thr359", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 359, "start_aa": "Thr", "end_pos": 359, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr359", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9PCG2-1" }, { "uniprot_canonical_ac": "M9PCH7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PCH7", "url": "https://www.uniprot.org/uniprotkb/M9PCH7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 54, "chemical_mass": 6691.0, "gene_names": "Dmel\\CG43815;CG43815;Dmel\\CG43815;Dmel_CG43815;FBgn0264363", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PCH7-1" }, { "uniprot_canonical_ac": "M9PCI3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PCI3", "url": "https://www.uniprot.org/uniprotkb/M9PCI3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 84, "chemical_mass": 9679.0, "gene_names": "Dmel\\CG43703;CG43703;Dmel\\CG43703;Dmel_CG43703", "protein_name": "BPTI/Kunitz inhibitor domain-containing protein", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "M9PCI3", "url": "https://www.uniprot.org/uniprotkb/M9PCI3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PCI3-1" }, { "uniprot_canonical_ac": "M9PCP3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PCP3", "url": "https://www.uniprot.org/uniprotkb/M9PCP3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1318, "chemical_mass": 147820.0, "gene_names": "mdcds_8484;CG9044;CT25972;Dmel\\CG9044;Dmel_CG9044;mdcds_8484", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9PCP3", "url": "https://www.uniprot.org/uniprotkb/M9PCP3" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "M9PCP3", "url": "https://www.uniprot.org/uniprotkb/M9PCP3" } ], "pmid": "" }, { "name": "protein sequestering activity", "id": "GO:0140311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140311", "evidence": [ { "database": "UniProtKB", "id": "M9PCP3", "url": "https://www.uniprot.org/uniprotkb/M9PCP3" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "M9PCP3", "url": "https://www.uniprot.org/uniprotkb/M9PCP3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PCP3-1" }, { "uniprot_canonical_ac": "M9PCS7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PCS7", "url": "https://www.uniprot.org/uniprotkb/M9PCS7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 37, "chemical_mass": 3912.0, "gene_names": "Dmel\\CG43813;CG43813;Dmel\\CG43813;Dmel_CG43813", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PCS7-1" }, { "uniprot_canonical_ac": "M9PCT4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PCT4", "url": "https://www.uniprot.org/uniprotkb/M9PCT4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 648, "chemical_mass": 73696.0, "gene_names": "Ir31a;31a;CG31718;DmelIR31a;Dmel\\CG31718;Dmel_CG31718;IR31a;Ir31a", "protein_name": "", "disease": [], "biological_process": [ { "name": "detection of chemical stimulus involved in sensory perception", "id": "GO:0050907", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050907", "evidence": [ { "database": "UniProtKB", "id": "M9PCT4", "url": "https://www.uniprot.org/uniprotkb/M9PCT4" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M9PCT4", "url": "https://www.uniprot.org/uniprotkb/M9PCT4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "M9PCT4", "url": "https://www.uniprot.org/uniprotkb/M9PCT4" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "M9PCT4", "url": "https://www.uniprot.org/uniprotkb/M9PCT4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PCT4-1" }, { "uniprot_canonical_ac": "M9PCZ7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 761, "chemical_mass": 81614.0, "gene_names": "SoxN;CG18024;DM64;Dmel\\CG18024;Dmel_CG18024;SOX29F;SOXB1;Sox B1;SoxN;Sry-rDM64;soxNeuro;soxN", "protein_name": "", "disease": [ { "disease_id": "DOID:0111779", "name": "X-linked panhypopituitarism", "description": "A combined pituitary hormone deficiency that has_material_basis_in duplications in the SOX3 gene on chromosome Xq27.1.", "url": "https://disease-ontology.org/term/DOID:0111779", "evidence": [ { "id": "0111779", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111779" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "regulation of neurogenesis", "id": "GO:0050767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050767", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "regulation of neural precursor cell proliferation", "id": "GO:2000177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000177", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "segment polarity determination", "id": "GO:0007367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007367", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "chitin-based larval cuticle pattern formation", "id": "GO:0035293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035293", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PCZ7-1", "start_pos": "621", "end_pos": "621", "site_lbl": "Thr621", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 621, "start_aa": "Thr", "end_pos": 621, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr621", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9PCZ7-1" }, { "uniprot_canonical_ac": "M9PE01-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 538, "chemical_mass": 61617.0, "gene_names": "Eip63E;CG10579;Dmel\\CG10579;Dmel_CG10579;EIP63E;Eip63E;L63;PFTAIRE;Pftaire;cdc2-63E", "protein_name": "cyclin-dependent kinase", "disease": [ { "disease_id": "DOID:0050453", "name": "lissencephaly", "description": "A congenital nervous system abnormality characterized by the absence of folds in the cerebral cortex and caused_by defective neuronal migration during the 12th to 24th weeks of gestation.", "url": "https://disease-ontology.org/term/DOID:0050453", "evidence": [ { "id": "0050453", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050453" } ], "weight": 0.0 }, { "disease_id": "DOID:0112231", "name": "lissencephaly 7 with cerebellar hypoplasia", "description": "A lissencephaly characterized by lack of psychomotor development, facial dysmorphism, arthrogryposis, and early-onset intractable seizures resulting in death in infancy that has_material_basis_in homozygous or compound heterozygous mutation in the CDK5 gene on chromosome 7q36.1.", "url": "https://disease-ontology.org/term/DOID:0112231", "evidence": [ { "id": "0112231", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112231" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activity", "id": "GO:0004693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004693", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "cyclin binding", "id": "GO:0030332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030332", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "cyclin-dependent protein kinase holoenzyme complex", "id": "GO:0000307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000307", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" } ], "biological_process": [ { "name": "developmental growth", "id": "GO:0048589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048589", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "regulation of cell cycle phase transition", "id": "GO:1901987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901987", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "morphogenesis of an epithelium", "id": "GO:0002009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002009", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "embryonic development via the syncytial blastoderm", "id": "GO:0001700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001700", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "instar larval development", "id": "GO:0002168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002168", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "metamorphosis", "id": "GO:0007552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007552", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PE01-1" }, { "uniprot_canonical_ac": "M9PEA4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PEA4", "url": "https://www.uniprot.org/uniprotkb/M9PEA4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 379, "chemical_mass": 43210.0, "gene_names": "Dmel\\CG10479;CG10479;Dmel\\CG10479;Dmel_CG10479", "protein_name": "SH2 domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PEA4-1" }, { "uniprot_canonical_ac": "M9PED9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PED9", "url": "https://www.uniprot.org/uniprotkb/M9PED9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 486, "chemical_mass": 54363.0, "gene_names": "Dmel\\CG15412;CG15412;Dmel\\CG15412;Dmel_CG15412", "protein_name": "", "disease": [], "cellular_component": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "M9PED9", "url": "https://www.uniprot.org/uniprotkb/M9PED9" } ], "pmid": "" } ], "biological_process": [ { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "M9PED9", "url": "https://www.uniprot.org/uniprotkb/M9PED9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PED9-1" }, { "uniprot_canonical_ac": "Q7KU89-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KU89", "url": "https://www.uniprot.org/uniprotkb/Q7KU89" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1904, "chemical_mass": 210734.0, "gene_names": "Pura;CG33167;CG33275;CG7511;CG7513;CG7515;CG7520;Dmel\\CG33275;Dmel_CG33275;Pura", "protein_name": "", "disease": [], "biological_process": [ { "name": "regulation of locomotor rhythm", "id": "GO:1904059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904059", "evidence": [ { "database": "UniProtKB", "id": "Q7KU89", "url": "https://www.uniprot.org/uniprotkb/Q7KU89" } ], "pmid": "" }, { "name": "neuron projection morphogenesis", "id": "GO:0048812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048812", "evidence": [ { "database": "UniProtKB", "id": "Q7KU89", "url": "https://www.uniprot.org/uniprotkb/Q7KU89" } ], "pmid": "" }, { "name": "positive regulation of Rho protein signal transduction", "id": "GO:0035025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035025", "evidence": [ { "database": "UniProtKB", "id": "Q7KU89", "url": "https://www.uniprot.org/uniprotkb/Q7KU89" } ], "pmid": "" }, { "name": "imaginal disc-derived leg morphogenesis", "id": "GO:0007480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007480", "evidence": [ { "database": "UniProtKB", "id": "Q7KU89", "url": "https://www.uniprot.org/uniprotkb/Q7KU89" } ], "pmid": "" } ], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "Q7KU89", "url": "https://www.uniprot.org/uniprotkb/Q7KU89" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7KU89-1", "start_pos": "1195", "end_pos": "1195", "site_lbl": "Thr1195", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1195, "start_aa": "Thr", "end_pos": 1195, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1195", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q7KU89-1", "start_pos": "741", "end_pos": "741", "site_lbl": "Thr741", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 741, "start_aa": "Thr", "end_pos": 741, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr741", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q7KU89-1" }, { "uniprot_canonical_ac": "M9PEG1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PEG1", "url": "https://www.uniprot.org/uniprotkb/M9PEG1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 694, "chemical_mass": 75620.0, "gene_names": "Dmel\\CG44195;CG44195;Dmel\\CG44195;Dmel_CG44195", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PEG1-1", "start_pos": "297", "end_pos": "297", "site_lbl": "Thr297", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 297, "start_aa": "Thr", "end_pos": 297, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr297", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9PEG1-1" }, { "uniprot_canonical_ac": "M9PEG2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PEG2", "url": "https://www.uniprot.org/uniprotkb/M9PEG2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 273, "chemical_mass": 30852.0, "gene_names": "Dmel\\CG13288;dmCG13288;CG13288;Dmel\\CG13288;Dmel_CG13288;dmCG13288", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "M9PEG2", "url": "https://www.uniprot.org/uniprotkb/M9PEG2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PEG2-1" }, { "uniprot_canonical_ac": "M9PEJ6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PEJ6", "url": "https://www.uniprot.org/uniprotkb/M9PEJ6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 105, "chemical_mass": 11243.0, "gene_names": "Dmel\\CG43915;CG43915;Dmel\\CG43915;Dmel_CG43915", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "M9PEJ6", "url": "https://www.uniprot.org/uniprotkb/M9PEJ6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PEJ6-1" }, { "uniprot_canonical_ac": "M9PEP2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PEP2", "url": "https://www.uniprot.org/uniprotkb/M9PEP2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1703, "chemical_mass": 188332.0, "gene_names": "Ac13E;AC 13E;AC13E;Ac13E;Ac35C;CG9210;DAC9;Dmel\\CG9210;Dmel_CG9210;ac13e;dADCY9", "protein_name": "Adenylate cyclase type 9", "disease": [ { "disease_id": "DOID:12716", "name": "newborn respiratory distress syndrome", "description": "A respiratory failure that is characterized by deficiency of the surfactant coating the inner surface of the lungs, by failure of the lungs to expand and contract properly during breathing with resulting collapse, and by the accumulation of a protein-containing film lining the alveoli and their ducts.", "url": "https://disease-ontology.org/term/DOID:12716", "evidence": [ { "id": "12716", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12716" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:9415", "name": "allergic asthma", "description": "An extrinsic asthma that is characterized by symptoms that are triggered by an allergic reaction caused by inhaled allergens such as dust mite allergen, pet dander, pollen and mold. The disease has_symptom coughing, has_symptom wheezing, has_symptom shortness of breath or has_symptom rapid breathing, and has_symptom chest tightness.", "url": "https://disease-ontology.org/term/DOID:9415", "evidence": [ { "id": "9415", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9415" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "adenylate cyclase activity", "id": "GO:0004016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004016", "evidence": [ { "database": "UniProtKB", "id": "M9PEP2", "url": "https://www.uniprot.org/uniprotkb/M9PEP2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "M9PEP2", "url": "https://www.uniprot.org/uniprotkb/M9PEP2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "M9PEP2", "url": "https://www.uniprot.org/uniprotkb/M9PEP2" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M9PEP2", "url": "https://www.uniprot.org/uniprotkb/M9PEP2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "M9PEP2", "url": "https://www.uniprot.org/uniprotkb/M9PEP2" } ], "pmid": "" } ], "biological_process": [ { "name": "cAMP biosynthetic process", "id": "GO:0006171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006171", "evidence": [ { "database": "UniProtKB", "id": "M9PEP2", "url": "https://www.uniprot.org/uniprotkb/M9PEP2" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "M9PEP2", "url": "https://www.uniprot.org/uniprotkb/M9PEP2" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "M9PEP2", "url": "https://www.uniprot.org/uniprotkb/M9PEP2" } ], "pmid": "" }, { "name": "adenylate cyclase-modulating G protein-coupled receptor signaling pathway", "id": "GO:0007188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007188", "evidence": [ { "database": "UniProtKB", "id": "M9PEP2", "url": "https://www.uniprot.org/uniprotkb/M9PEP2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PEP2-1" }, { "uniprot_canonical_ac": "M9PEY3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PEY3", "url": "https://www.uniprot.org/uniprotkb/M9PEY3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 81, "chemical_mass": 9573.0, "gene_names": "Dmel\\CG43993;CG43993;Dmel\\CG43993;Dmel_CG43993", "protein_name": "Seminal fluid protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PEY3-1" }, { "uniprot_canonical_ac": "M9PF61-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 350, "chemical_mass": 40137.0, "gene_names": "Ar1;34F4T;AR;Akr1B;CG6084;Dmel\\CG6084;ESTS:34F4T;dAR1", "protein_name": "Aldo-keto reductase 1B", "disease": [ { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:1205", "name": "allergic disease", "description": "An immune system disease that is an exaggerated immune response to allergens, such as insect venom, dust mites, pollen, pet dander, drugs or some foods.", "url": "https://disease-ontology.org/term/DOID:1205", "evidence": [ { "id": "1205", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1205" } ], "weight": 0.0 }, { "disease_id": "DOID:2349", "name": "arteriosclerosis", "description": "An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries.", "url": "https://disease-ontology.org/term/DOID:2349", "evidence": [ { "id": "2349", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2349" } ], "weight": 0.0 }, { "disease_id": "DOID:4195", "name": "hyperglycemia", "description": "", "url": "https://disease-ontology.org/term/DOID:4195", "evidence": [ { "id": "4195", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4195" } ], "weight": 0.0 }, { "disease_id": "DOID:4500", "name": "hypokalemia", "description": "", "url": "https://disease-ontology.org/term/DOID:4500", "evidence": [ { "id": "4500", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4500" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:83", "name": "cataract", "description": "A lens disease characterized by clouding of the lens inside the eye which leads to a decrease in vision.", "url": "https://disease-ontology.org/term/DOID:83", "evidence": [ { "id": "83", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:83" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9743", "name": "diabetic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:9743", "evidence": [ { "id": "9743", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9743" } ], "weight": 0.0 }, { "disease_id": "DOID:9870", "name": "galactosemia", "description": "A carbohydrate metabolic disorder that involves a defect in galactose metabolism resulting in toxic levels of galactose 1-phosphate in various tissues.", "url": "https://disease-ontology.org/term/DOID:9870", "evidence": [ { "id": "9870", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9870" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "pmid": "" } ], "molecular_function": [ { "name": "aldose reductase (NADPH) activity", "id": "GO:0004032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004032", "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "pmid": "" }, { "name": "L-glucuronate reductase activity", "id": "GO:0047939", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047939", "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "pmid": "" }, { "name": "prostaglandin H2 endoperoxidase reductase activity", "id": "GO:0036130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036130", "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "pmid": "" }, { "name": "all-trans-retinol dehydrogenase (NADP+) activity", "id": "GO:0052650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052650", "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "pmid": "" }, { "name": "glycerol dehydrogenase (NADP+) activity", "id": "GO:0047956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047956", "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "pmid": "" }, { "name": "allyl-alcohol dehydrogenase activity", "id": "GO:0047655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047655", "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "pmid": "" } ], "biological_process": [ { "name": "sorbitol biosynthetic process", "id": "GO:0006061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006061", "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "pmid": "" }, { "name": "fructose biosynthetic process", "id": "GO:0046370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046370", "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "pmid": "" }, { "name": "D-glucuronate catabolic process to D-xylulose 5-phosphate", "id": "GO:0019640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019640", "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "pmid": "" }, { "name": "polyol biosynthetic process", "id": "GO:0046173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046173", "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PF61-1" }, { "uniprot_canonical_ac": "M9PF81-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PF81", "url": "https://www.uniprot.org/uniprotkb/M9PF81" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 356, "chemical_mass": 38795.0, "gene_names": "Dmel\\CG7906;CG7906;Dmel\\CG7906;Dmel_CG7906", "protein_name": "Kazal-like domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PF81-1" }, { "uniprot_canonical_ac": "M9PF84-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 818, "chemical_mass": 90298.0, "gene_names": "klu;CG12296;Dmel\\CG12296;Dmel_CG12296;KLU;Klu;P09036;klu;l(3)09036;l(3)10052", "protein_name": "", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "neurogenesis", "id": "GO:0022008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022008", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "positive regulation of neuroblast proliferation", "id": "GO:0002052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002052", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "neuronal stem cell population maintenance", "id": "GO:0097150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097150", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "regulation of stem cell division", "id": "GO:2000035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000035", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "regulation of neuroblast proliferation", "id": "GO:1902692", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902692", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "R7 cell differentiation", "id": "GO:0045466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045466", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "positive regulation of compound eye retinal cell programmed cell death", "id": "GO:0046672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046672", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "neuroblast development", "id": "GO:0014019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014019", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "sensory organ precursor cell fate determination", "id": "GO:0016360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016360", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "larval feeding behavior", "id": "GO:0030536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030536", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "cis-regulatory region sequence-specific DNA binding", "id": "GO:0000987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000987", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PF84-1", "start_pos": "594", "end_pos": "594", "site_lbl": "Thr594", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 594, "start_aa": "Thr", "end_pos": 594, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr594", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9PF84-1" }, { "uniprot_canonical_ac": "M9PFA9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PFA9", "url": "https://www.uniprot.org/uniprotkb/M9PFA9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 412, "chemical_mass": 46885.0, "gene_names": "Dmel\\CG10654;CG10654;Dmel\\CG10654;Dmel_CG10654", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "M9PFA9", "url": "https://www.uniprot.org/uniprotkb/M9PFA9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "M9PFA9", "url": "https://www.uniprot.org/uniprotkb/M9PFA9" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "M9PFA9", "url": "https://www.uniprot.org/uniprotkb/M9PFA9" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "M9PFA9", "url": "https://www.uniprot.org/uniprotkb/M9PFA9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "M9PFA9", "url": "https://www.uniprot.org/uniprotkb/M9PFA9" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "M9PFA9", "url": "https://www.uniprot.org/uniprotkb/M9PFA9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PFA9", "url": "https://www.uniprot.org/uniprotkb/M9PFA9" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "M9PFA9", "url": "https://www.uniprot.org/uniprotkb/M9PFA9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "M9PFA9", "url": "https://www.uniprot.org/uniprotkb/M9PFA9" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "M9PFA9", "url": "https://www.uniprot.org/uniprotkb/M9PFA9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PFA9-1" }, { "uniprot_canonical_ac": "M9PFK3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PFK3", "url": "https://www.uniprot.org/uniprotkb/M9PFK3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 240, "chemical_mass": 26503.0, "gene_names": "BcDNA:RH23514;BcDNA:RH23514;CG16743;Dmel\\CG16743;Dmel_CG16743", "protein_name": "CG16743 protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PFK3-1" }, { "uniprot_canonical_ac": "Q86BI6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q86BI6", "url": "https://www.uniprot.org/uniprotkb/Q86BI6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 282, "chemical_mass": 31993.0, "gene_names": "Dmel\\CG33061;CG13057;CG33061;Dmel\\CG33061;Dmel_CG33061", "protein_name": "Trimeric intracellular cation channel type B", "disease": [ { "disease_id": "DOID:0110343", "name": "osteogenesis imperfecta type 14", "description": "An osteogenesis imperfecta that has_material_basis_in mutation in the TMEM38B gene on chromosome 9q31.", "url": "https://disease-ontology.org/term/DOID:0110343", "evidence": [ { "id": "0110343", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110343" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q86BI6", "url": "https://www.uniprot.org/uniprotkb/Q86BI6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q86BI6", "url": "https://www.uniprot.org/uniprotkb/Q86BI6" } ], "pmid": "" }, { "name": "sarcoplasmic reticulum", "id": "GO:0016529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016529", "evidence": [ { "database": "UniProtKB", "id": "Q86BI6", "url": "https://www.uniprot.org/uniprotkb/Q86BI6" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q86BI6", "url": "https://www.uniprot.org/uniprotkb/Q86BI6" } ], "pmid": "" }, { "name": "potassium channel activity", "id": "GO:0005267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005267", "evidence": [ { "database": "UniProtKB", "id": "Q86BI6", "url": "https://www.uniprot.org/uniprotkb/Q86BI6" } ], "pmid": "" } ], "biological_process": [ { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "Q86BI6", "url": "https://www.uniprot.org/uniprotkb/Q86BI6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q86BI6-1" }, { "uniprot_canonical_ac": "M9PFR6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PFR6", "url": "https://www.uniprot.org/uniprotkb/M9PFR6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 188, "chemical_mass": 20453.0, "gene_names": "mbf1;BcDNA:GH10148;BcDNA:GM01267;CG4143;Dmel\\CG4143;Dmel_CG4143;MBF-1;MBF1;MRE4;Mbf-1;Mbf1;mbf1", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "M9PFR6", "url": "https://www.uniprot.org/uniprotkb/M9PFR6" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "M9PFR6", "url": "https://www.uniprot.org/uniprotkb/M9PFR6" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "M9PFR6", "url": "https://www.uniprot.org/uniprotkb/M9PFR6" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "M9PFR6", "url": "https://www.uniprot.org/uniprotkb/M9PFR6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PFR6", "url": "https://www.uniprot.org/uniprotkb/M9PFR6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9PFR6", "url": "https://www.uniprot.org/uniprotkb/M9PFR6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "M9PFR6", "url": "https://www.uniprot.org/uniprotkb/M9PFR6" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "M9PFR6", "url": "https://www.uniprot.org/uniprotkb/M9PFR6" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "M9PFR6", "url": "https://www.uniprot.org/uniprotkb/M9PFR6" } ], "pmid": "" }, { "name": "mRNA stabilization", "id": "GO:0048255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048255", "evidence": [ { "database": "UniProtKB", "id": "M9PFR6", "url": "https://www.uniprot.org/uniprotkb/M9PFR6" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "M9PFR6", "url": "https://www.uniprot.org/uniprotkb/M9PFR6" } ], "pmid": "" }, { "name": "open tracheal system development", "id": "GO:0007424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007424", "evidence": [ { "database": "UniProtKB", "id": "M9PFR6", "url": "https://www.uniprot.org/uniprotkb/M9PFR6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PFR6-1" }, { "uniprot_canonical_ac": "M9PFU2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PFU2", "url": "https://www.uniprot.org/uniprotkb/M9PFU2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 889, "chemical_mass": 96043.0, "gene_names": "Crtc;CG6064;CRTC;Crtc;Dmel\\CG6064;Dmel_CG6064;MTORC1;ORE-12;TOR-C2;TORC1;TORC2;TORC;Tor-C2;cg6064;crtc;dTORC2;dTORC;mTORC1;mTORC", "protein_name": "", "disease": [ { "disease_id": "DOID:1470", "name": "major depressive disorder", "description": "A depressive disorder that is characterized by at least two weeks of loss of interest or pleasure in normally enjoyable activities or depressed mood along with additional cognitive or somatic impairments such as appetite or weight changes, sleep difficulties, psychomotor agitation or retardation, fatigue or loss of energy, diminished ability to think or concentrate, feelings of worthlessness or excessive guilt, and suicidality.", "url": "https://disease-ontology.org/term/DOID:1470", "evidence": [ { "id": "1470", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1470" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "M9PFU2", "url": "https://www.uniprot.org/uniprotkb/M9PFU2" } ], "pmid": "" }, { "name": "cAMP response element binding protein binding", "id": "GO:0008140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008140", "evidence": [ { "database": "UniProtKB", "id": "M9PFU2", "url": "https://www.uniprot.org/uniprotkb/M9PFU2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PFU2", "url": "https://www.uniprot.org/uniprotkb/M9PFU2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9PFU2", "url": "https://www.uniprot.org/uniprotkb/M9PFU2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "M9PFU2", "url": "https://www.uniprot.org/uniprotkb/M9PFU2" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "M9PFU2", "url": "https://www.uniprot.org/uniprotkb/M9PFU2" } ], "pmid": "" }, { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "M9PFU2", "url": "https://www.uniprot.org/uniprotkb/M9PFU2" } ], "pmid": "" }, { "name": "response to starvation", "id": "GO:0042594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042594", "evidence": [ { "database": "UniProtKB", "id": "M9PFU2", "url": "https://www.uniprot.org/uniprotkb/M9PFU2" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "M9PFU2", "url": "https://www.uniprot.org/uniprotkb/M9PFU2" } ], "pmid": "" }, { "name": "protein homotetramerization", "id": "GO:0051289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051289", "evidence": [ { "database": "UniProtKB", "id": "M9PFU2", "url": "https://www.uniprot.org/uniprotkb/M9PFU2" } ], "pmid": "" }, { "name": "cellular response to cAMP", "id": "GO:0071320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071320", "evidence": [ { "database": "UniProtKB", "id": "M9PFU2", "url": "https://www.uniprot.org/uniprotkb/M9PFU2" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "M9PFU2", "url": "https://www.uniprot.org/uniprotkb/M9PFU2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PFU2-1" }, { "uniprot_canonical_ac": "M9PFU4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PFU4", "url": "https://www.uniprot.org/uniprotkb/M9PFU4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 374, "chemical_mass": 42925.0, "gene_names": "Dmel\\CG44006;CG34252;CG44006;Dmel\\CG44006;Dmel_CG44006", "protein_name": "F-box domain-containing protein", "disease": [], "molecular_function": [ { "name": "SCF ubiquitin ligase complex binding", "id": "GO:1905761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905761", "evidence": [ { "database": "UniProtKB", "id": "M9PFU4", "url": "https://www.uniprot.org/uniprotkb/M9PFU4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PFU4-1" }, { "uniprot_canonical_ac": "M9PFX3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PFX3", "url": "https://www.uniprot.org/uniprotkb/M9PFX3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 118, "chemical_mass": 13976.0, "gene_names": "Dmel\\CG43954;CG43954;Dmel\\CG43954;Dmel_CG43954", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "M9PFX3", "url": "https://www.uniprot.org/uniprotkb/M9PFX3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PFX3-1" }, { "uniprot_canonical_ac": "M9PG08-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 783, "chemical_mass": 89669.0, "gene_names": "RhoBTB;28574635;CG5701;Dmel\\CG5701;Dmel_CG5701;RhoBTB;RhoGTPase;RhoX", "protein_name": "", "disease": [ { "disease_id": "DOID:0070375", "name": "developmental and epileptic encephalopathy 64", "description": "A developmental and epileptic encephalopathy characterized by infantile onset of seizures, severe intellectual disabilities, impaired motor functions, movement disorders, and postnatal microcephaly that has_material_basis_in heterozygous mutation in the RHOBTB2 gene on chromosome 8p21.", "url": "https://disease-ontology.org/term/DOID:0070375", "evidence": [ { "id": "0070375", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070375" } ], "weight": 0.0 } ], "biological_process": [ { "name": "developmental process involved in reproduction", "id": "GO:0003006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003006", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "epithelium development", "id": "GO:0060429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060429", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "establishment or maintenance of cell polarity", "id": "GO:0007163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007163", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "cortical cytoskeleton organization", "id": "GO:0030865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030865", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "ameboidal-type cell migration", "id": "GO:0001667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001667", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "cellular process involved in reproduction in multicellular organism", "id": "GO:0022412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022412", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "melanotic encapsulation of foreign target", "id": "GO:0035011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035011", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "hemocyte migration", "id": "GO:0035099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035099", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PG08-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Thr27", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 27, "start_aa": "Thr", "end_pos": 27, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr27", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "M9PG08", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=M9PG08" } ] } ] } ], "record_id": "M9PG08-1" }, { "uniprot_canonical_ac": "M9PGH7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1657, "chemical_mass": 183541.0, "gene_names": "G9a;CG2995;Dmel\\CG2995;Dmel_CG2995;EG:BACR37P7.2;EHMT;G9ae;G9a;cab65850 G9a Dm;dG9a", "protein_name": "", "disease": [ { "disease_id": "DOID:0050156", "name": "idiopathic pulmonary fibrosis", "description": "A pulmonary fibrosis that is characterized by scarring of the lung characterized by stiffness in the lungs and makes it difficult to breathe.", "url": "https://disease-ontology.org/term/DOID:0050156", "evidence": [ { "id": "0050156", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050156" } ], "weight": 0.0 }, { "disease_id": "DOID:0050696", "name": "fetal alcohol spectrum disorder", "description": "A specific developmental disorder and physical disorder that is characterized by physical, behavioral and learning birth defects resulting from maternal ingestion of alcohol during pregnancy.", "url": "https://disease-ontology.org/term/DOID:0050696", "evidence": [ { "id": "0050696", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050696" } ], "weight": 0.0 }, { "disease_id": "DOID:0060352", "name": "Kleefstra syndrome 1", "description": "A Kleefstra syndrome that is characterized by severe mental retardation, hypotonia, microcephaly, epileptic seizures, flat face with hypertelorism, synophrys, anteverted nares, everted lower lip, carp mouth with macroglossia, and heart defects and that has_material_basis_in a microdeletion in the chromosome region 9q34.3 or by a point mutation in the EHMT1 gene located in that region.", "url": "https://disease-ontology.org/term/DOID:0060352", "evidence": [ { "id": "0060352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060352" } ], "weight": 0.0 }, { "disease_id": "DOID:0080597", "name": "Kleefstra syndrome", "description": "A syndrome that is characterized by developmental delay and intellectual disability, severely limited or absent speech, and weak muscle tone.", "url": "https://disease-ontology.org/term/DOID:0080597", "evidence": [ { "id": "0080597", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080597" } ], "weight": 0.0 }, { "disease_id": "DOID:1909", "name": "melanoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from melanocytes which are found in skin, the bowel and the eye.", "url": "https://disease-ontology.org/term/DOID:1909", "evidence": [ { "id": "1909", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1909" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:934", "name": "viral infectious disease", "description": "A disease by infectious agent that results in infection, has_material_basis_in Viruses.", "url": "https://disease-ontology.org/term/DOID:934", "evidence": [ { "id": "934", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:934" } ], "weight": 0.0 }, { "disease_id": "DOID:986", "name": "alopecia areata", "description": "An autoimmune disease resulting in the loss of hair on the scalp and elsewhere on the body initially causing bald spots.", "url": "https://disease-ontology.org/term/DOID:986", "evidence": [ { "id": "986", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:986" } ], "weight": 0.0 } ], "biological_process": [ { "name": "habituation", "id": "GO:0046959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046959", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "short-term memory", "id": "GO:0007614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007614", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "response to virus", "id": "GO:0009615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009615", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "positive regulation of dendrite morphogenesis", "id": "GO:0050775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050775", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "long-term memory", "id": "GO:0007616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007616", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "epigenetic regulation of gene expression", "id": "GO:0040029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040029", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "larval locomotory behavior", "id": "GO:0008345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008345", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "facultative heterochromatin formation", "id": "GO:0140718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140718", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "euchromatin", "id": "GO:0000791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000791", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "polytene chromosome interband", "id": "GO:0005705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005705", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "p53 binding", "id": "GO:0002039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002039", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "histone H3K9 methyltransferase activity", "id": "GO:0046974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046974", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "histone H3K9 monomethyltransferase activity", "id": "GO:0140948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140948", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "histone H3K9 dimethyltransferase activity", "id": "GO:0140942", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140942", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "histone H3K27 monomethyltransferase activity", "id": "GO:0140953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140953", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "histone H3K9 trimethyltransferase activity", "id": "GO:0140949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140949", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "histone H4 methyltransferase activity", "id": "GO:0140939", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140939", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "histone H3K27 trimethyltransferase activity", "id": "GO:0140951", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140951", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "histone H3K27 dimethyltransferase activity", "id": "GO:0140952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140952", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PGH7-1" }, { "uniprot_canonical_ac": "M9PGR0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PGR0", "url": "https://www.uniprot.org/uniprotkb/M9PGR0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 176, "chemical_mass": 19794.0, "gene_names": "Dlip1;CG15367;DIP1;Dip1;Dlip1;Dmel\\CG15367;Dmel_CG15367;dip1;dlip", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PGR0", "url": "https://www.uniprot.org/uniprotkb/M9PGR0" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "M9PGR0", "url": "https://www.uniprot.org/uniprotkb/M9PGR0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PGR0-1" }, { "uniprot_canonical_ac": "M9PHC0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PHC0", "url": "https://www.uniprot.org/uniprotkb/M9PHC0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 261, "chemical_mass": 30604.0, "gene_names": "Dmel\\CG32718;CG32718;Dmel\\CG32718;Dmel_CG32718", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PHC0-1" }, { "uniprot_canonical_ac": "M9PH26-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PH26", "url": "https://www.uniprot.org/uniprotkb/M9PH26" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 191, "chemical_mass": 21445.0, "gene_names": "HLH4C;CG3052;Dmel\\CG3052;Dmel_CG3052;DroNHLH;EG:84H4.2;HLH4C;bHLH36", "protein_name": "", "disease": [], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "M9PH26", "url": "https://www.uniprot.org/uniprotkb/M9PH26" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "M9PH26", "url": "https://www.uniprot.org/uniprotkb/M9PH26" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "M9PH26", "url": "https://www.uniprot.org/uniprotkb/M9PH26" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "M9PH26", "url": "https://www.uniprot.org/uniprotkb/M9PH26" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "M9PH26", "url": "https://www.uniprot.org/uniprotkb/M9PH26" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "M9PH26", "url": "https://www.uniprot.org/uniprotkb/M9PH26" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "M9PH26", "url": "https://www.uniprot.org/uniprotkb/M9PH26" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "M9PH26", "url": "https://www.uniprot.org/uniprotkb/M9PH26" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "M9PH26", "url": "https://www.uniprot.org/uniprotkb/M9PH26" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PH26-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Thr73", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 73, "start_aa": "Thr", "end_pos": 73, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr73", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9PH26-1" }, { "uniprot_canonical_ac": "M9PHF7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PHF7", "url": "https://www.uniprot.org/uniprotkb/M9PHF7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 432, "chemical_mass": 47654.0, "gene_names": "Dmel\\CG12992;CG12992;Dmel\\CG12992;Dmel_CG12992", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PHF7-1" }, { "uniprot_canonical_ac": "M9PHI7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PHI7", "url": "https://www.uniprot.org/uniprotkb/M9PHI7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 261, "chemical_mass": 28835.0, "gene_names": "kri;CG5537;Dmel\\CG5537;Dmel_CG5537;anon-EST:Posey275;kri;uprt", "protein_name": "Uracil phosphoribosyltransferase homolog", "disease": [], "molecular_function": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "M9PHI7", "url": "https://www.uniprot.org/uniprotkb/M9PHI7" } ], "pmid": "" }, { "name": "uracil phosphoribosyltransferase activity", "id": "GO:0004845", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004845", "evidence": [ { "database": "UniProtKB", "id": "M9PHI7", "url": "https://www.uniprot.org/uniprotkb/M9PHI7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PHI7", "url": "https://www.uniprot.org/uniprotkb/M9PHI7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9PHI7", "url": "https://www.uniprot.org/uniprotkb/M9PHI7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PHI7-1" }, { "uniprot_canonical_ac": "M9PHK6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PHK6", "url": "https://www.uniprot.org/uniprotkb/M9PHK6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 586, "chemical_mass": 64914.0, "gene_names": "Dmel\\CG14221;CG14221;Dmel\\CG14221;Dmel_CG14221", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PHK6-1" }, { "uniprot_canonical_ac": "M9PHS8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PHS8", "url": "https://www.uniprot.org/uniprotkb/M9PHS8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 519, "chemical_mass": 60183.0, "gene_names": "Dmel\\CG9784;CG9784;Dmel\\CG9784;Dmel_CG9784;IPP;lincRNA.S9473", "protein_name": "Inositol polyphosphate-related phosphatase domain-containing protein", "disease": [ { "disease_id": "DOID:0050588", "name": "muscular dystrophy-dystroglycanopathy type B1", "description": "A congenital muscular dystrophy characterized by muscle weakness, cognitive impairment and brain abnormalities and has_material_basis_in mutation to the POMT1 gene that encodes O-mannosyltransferase.", "url": "https://disease-ontology.org/term/DOID:0050588", "evidence": [ { "id": "0050588", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050588" } ], "weight": 0.0 }, { "disease_id": "DOID:0080197", "name": "congenital muscular dystrophy with cataracts and intellectual disability", "description": "A congenital muscular dystrophy characterized by onset of progressive muscle weakness in early childhood with autosomal recessive inheritance that has_material_basis_in homozygous or compound heterozygous mutation in the INPP5K gene (607875) on chromosome 17p13.", "url": "https://disease-ontology.org/term/DOID:0080197", "evidence": [ { "id": "0080197", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080197" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M9PHS8", "url": "https://www.uniprot.org/uniprotkb/M9PHS8" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "M9PHS8", "url": "https://www.uniprot.org/uniprotkb/M9PHS8" } ], "pmid": "" }, { "name": "ruffle", "id": "GO:0001726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001726", "evidence": [ { "database": "UniProtKB", "id": "M9PHS8", "url": "https://www.uniprot.org/uniprotkb/M9PHS8" } ], "pmid": "" } ], "biological_process": [ { "name": "phosphatidylinositol dephosphorylation", "id": "GO:0046856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046856", "evidence": [ { "database": "UniProtKB", "id": "M9PHS8", "url": "https://www.uniprot.org/uniprotkb/M9PHS8" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity", "id": "GO:0004439", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004439", "evidence": [ { "database": "UniProtKB", "id": "M9PHS8", "url": "https://www.uniprot.org/uniprotkb/M9PHS8" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity", "id": "GO:0034485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034485", "evidence": [ { "database": "UniProtKB", "id": "M9PHS8", "url": "https://www.uniprot.org/uniprotkb/M9PHS8" } ], "pmid": "" }, { "name": "inositol trisphosphate phosphatase activity", "id": "GO:0046030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046030", "evidence": [ { "database": "UniProtKB", "id": "M9PHS8", "url": "https://www.uniprot.org/uniprotkb/M9PHS8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PHS8-1" }, { "uniprot_canonical_ac": "M9PHT8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PHT8", "url": "https://www.uniprot.org/uniprotkb/M9PHT8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 496, "chemical_mass": 55070.0, "gene_names": "CT15971;CG4991;CT15971;Dmel\\CG4991;Dmel_CG4991", "protein_name": "Amino acid transporter transmembrane domain-containing protein", "disease": [ { "disease_id": "DOID:0112265", "name": "iminoglycinuria", "description": "A renal tubular transport disease characterized by impaired renal tube reabsorption of proline, hydroxyproline and glycine and elevated urine levels of the imino acids and glycine that has_material_basis_in homozygous mutation in SLC36A2 on chromosome 5q33.1 combined with either heterozygous mutation in SLC6A20 gene on chromosome 3p21.31 or homozygous mutation in SLC6A19 on chromosome 5p15.33.", "url": "https://disease-ontology.org/term/DOID:0112265", "evidence": [ { "id": "0112265", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112265" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "L-amino acid transmembrane transporter activity", "id": "GO:0015179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015179", "evidence": [ { "database": "UniProtKB", "id": "M9PHT8", "url": "https://www.uniprot.org/uniprotkb/M9PHT8" } ], "pmid": "" }, { "name": "amino acid transmembrane transporter activity", "id": "GO:0015171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015171", "evidence": [ { "database": "UniProtKB", "id": "M9PHT8", "url": "https://www.uniprot.org/uniprotkb/M9PHT8" } ], "pmid": "" } ], "cellular_component": [ { "name": "vacuolar membrane", "id": "GO:0005774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005774", "evidence": [ { "database": "UniProtKB", "id": "M9PHT8", "url": "https://www.uniprot.org/uniprotkb/M9PHT8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "M9PHT8", "url": "https://www.uniprot.org/uniprotkb/M9PHT8" } ], "pmid": "" } ], "biological_process": [ { "name": "amino acid transmembrane transport", "id": "GO:0003333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003333", "evidence": [ { "database": "UniProtKB", "id": "M9PHT8", "url": "https://www.uniprot.org/uniprotkb/M9PHT8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PHT8-1" }, { "uniprot_canonical_ac": "M9PHX0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PHX0", "url": "https://www.uniprot.org/uniprotkb/M9PHX0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 345, "chemical_mass": 39524.0, "gene_names": "Dmel\\CG43843;CG15049;CG43843;Dmel\\CG43843;Dmel_CG43843", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PHX0-1" }, { "uniprot_canonical_ac": "M9PI41-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1858, "chemical_mass": 211780.0, "gene_names": "sti;CG10522;CIT-K;CIT;Citron K;Citron;DCK;Dmel\\CG10522;Dmel_CG10522;STI;anon-WO0118547.388;cit;ck;dck;l(3)7m-62;l(3)7m62;l(3)SG21;sti/Citron;sti", "protein_name": "non-specific serine/threonine protein kinase", "disease": [ { "disease_id": "DOID:0070288", "name": "primary autosomal recessive microcephaly 17", "description": "A primary autosomal recessive microcephaly that has_material_basis_in homozygous or compound heterozygous mutation in the CIT gene on chromosome 12q24.", "url": "https://disease-ontology.org/term/DOID:0070288", "evidence": [ { "id": "0070288", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070288" } ], "weight": 0.0 }, { "disease_id": "DOID:0070297", "name": "primary microcephaly", "description": "A microcephaly characterized by microcephaly present at birth, where the brain is small but has normal architecture, and nonprogressive mental retardation.", "url": "https://disease-ontology.org/term/DOID:0070297", "evidence": [ { "id": "0070297", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070297" } ], "weight": 0.0 }, { "disease_id": "DOID:0081292", "name": "traumatic brain injury", "description": "A brain disease that is characterized by brain dysfunction caused by an outside force, usually a violent blow to the head.", "url": "https://disease-ontology.org/term/DOID:0081292", "evidence": [ { "id": "0081292", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081292" } ], "weight": 0.0 }, { "disease_id": "DOID:10907", "name": "microcephaly", "description": "A congenital nervous system abnormality that is characterized by a significantly smaller than normal head in infants.", "url": "https://disease-ontology.org/term/DOID:10907", "evidence": [ { "id": "10907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10907" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" }, { "name": "actomyosin contractile ring", "id": "GO:0005826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005826", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" }, { "name": "actomyosin structure organization", "id": "GO:0031032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031032", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" }, { "name": "negative regulation of hippo signaling", "id": "GO:0035331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035331", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" }, { "name": "actomyosin contractile ring assembly", "id": "GO:0000915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000915", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" }, { "name": "regulation of cytokinesis", "id": "GO:0032465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032465", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" }, { "name": "regulation of cytokinesis, actomyosin contractile ring assembly", "id": "GO:2000431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000431", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" }, { "name": "male meiosis cytokinesis", "id": "GO:0007112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007112", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" }, { "name": "ventral cord development", "id": "GO:0007419", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007419", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PI41-1" }, { "uniprot_canonical_ac": "Q59E08-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q59E08", "url": "https://www.uniprot.org/uniprotkb/Q59E08" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 271, "chemical_mass": 31109.0, "gene_names": "Jhbp6;BcDNA:LP08817;CG14457;CG18618;Dmel\\CG14457;Dmel_CG14457;JHBP6;Jhbp6", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q59E08", "url": "https://www.uniprot.org/uniprotkb/Q59E08" } ], "pmid": "" } ], "biological_process": [ { "name": "circadian rhythm", "id": "GO:0007623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007623", "evidence": [ { "database": "UniProtKB", "id": "Q59E08", "url": "https://www.uniprot.org/uniprotkb/Q59E08" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q59E08-1" }, { "uniprot_canonical_ac": "M9PJS6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PJS6", "url": "https://www.uniprot.org/uniprotkb/M9PJS6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 603, "chemical_mass": 65049.0, "gene_names": "CG17602;Dmel\\CG17600;CG17600;CG17602;Dmel\\CG17600;Dmel_CG17600", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "M9PJS6", "url": "https://www.uniprot.org/uniprotkb/M9PJS6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PJS6-1" }, { "uniprot_canonical_ac": "O76888-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "O76888", "url": "https://www.uniprot.org/uniprotkb/O76888" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 116, "chemical_mass": 12646.0, "gene_names": "Dmel\\CG14795;CG14795;Dmel\\CG14795;Dmel_CG14795;EG:196F3.3", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "O76888-1" }, { "uniprot_canonical_ac": "O96532-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "O96532", "url": "https://www.uniprot.org/uniprotkb/O96532" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 535, "chemical_mass": 59417.0, "gene_names": "Rad17;24;CG7825;DmRad17/24;Dmel\\CG7825;Dmel_CG7825;Rad17", "protein_name": "", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "O96532", "url": "https://www.uniprot.org/uniprotkb/O96532" } ], "pmid": "" }, { "name": "chromatin-protein adaptor activity", "id": "GO:0140463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140463", "evidence": [ { "database": "UniProtKB", "id": "O96532", "url": "https://www.uniprot.org/uniprotkb/O96532" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "O96532", "url": "https://www.uniprot.org/uniprotkb/O96532" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "O96532", "url": "https://www.uniprot.org/uniprotkb/O96532" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "O96532", "url": "https://www.uniprot.org/uniprotkb/O96532" } ], "pmid": "" }, { "name": "Rad17 RFC-like complex", "id": "GO:0031389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031389", "evidence": [ { "database": "UniProtKB", "id": "O96532", "url": "https://www.uniprot.org/uniprotkb/O96532" } ], "pmid": "" }, { "name": "chromosome, telomeric repeat region", "id": "GO:0140445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140445", "evidence": [ { "database": "UniProtKB", "id": "O96532", "url": "https://www.uniprot.org/uniprotkb/O96532" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "O96532", "url": "https://www.uniprot.org/uniprotkb/O96532" } ], "pmid": "" }, { "name": "mitotic intra-S DNA damage checkpoint signaling", "id": "GO:0031573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031573", "evidence": [ { "database": "UniProtKB", "id": "O96532", "url": "https://www.uniprot.org/uniprotkb/O96532" } ], "pmid": "" }, { "name": "mitotic DNA replication checkpoint signaling", "id": "GO:0033314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033314", "evidence": [ { "database": "UniProtKB", "id": "O96532", "url": "https://www.uniprot.org/uniprotkb/O96532" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "O96532-1", "start_pos": "136", "end_pos": "136", "site_lbl": "Thr136", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 136, "start_aa": "Thr", "end_pos": 136, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr136", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "O96532-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Thr28", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 28, "start_aa": "Thr", "end_pos": 28, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr28", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "O96532-1" }, { "uniprot_canonical_ac": "Q0E8E7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0E8E7", "url": "https://www.uniprot.org/uniprotkb/Q0E8E7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 276, "chemical_mass": 31468.0, "gene_names": "Tsen34;CG13470;CG33260;Dmel\\CG33260;Dmel_CG33260;TSEN34;Tsen34", "protein_name": "tRNA-splicing endonuclease subunit Sen34", "disease": [ { "disease_id": "DOID:0060269", "name": "pontocerebellar hypoplasia type 2C", "description": "A severe pontocerebellar hypoplasia that is characterized by progressive microcephaly, extrapyramidal dyskinesia, seizure and failure to thrive, has_material_basis_in autosomal recessive inheritance of mutation in the TSEN34 gene.", "url": "https://disease-ontology.org/term/DOID:0060269", "evidence": [ { "id": "0060269", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060269" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q0E8E7", "url": "https://www.uniprot.org/uniprotkb/Q0E8E7" } ], "pmid": "" }, { "name": "tRNA-intron endonuclease complex", "id": "GO:0000214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000214", "evidence": [ { "database": "UniProtKB", "id": "Q0E8E7", "url": "https://www.uniprot.org/uniprotkb/Q0E8E7" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q0E8E7", "url": "https://www.uniprot.org/uniprotkb/Q0E8E7" } ], "pmid": "" }, { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "Q0E8E7", "url": "https://www.uniprot.org/uniprotkb/Q0E8E7" } ], "pmid": "" }, { "name": "tRNA-type intron splice site recognition and cleavage", "id": "GO:0000379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000379", "evidence": [ { "database": "UniProtKB", "id": "Q0E8E7", "url": "https://www.uniprot.org/uniprotkb/Q0E8E7" } ], "pmid": "" } ], "molecular_function": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "Q0E8E7", "url": "https://www.uniprot.org/uniprotkb/Q0E8E7" } ], "pmid": "" }, { "name": "tRNA-intron lyase activity", "id": "GO:0000213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000213", "evidence": [ { "database": "UniProtKB", "id": "Q0E8E7", "url": "https://www.uniprot.org/uniprotkb/Q0E8E7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q0E8E7-1" }, { "uniprot_canonical_ac": "Q0E8H9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0E8H9", "url": "https://www.uniprot.org/uniprotkb/Q0E8H9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 622, "chemical_mass": 70558.0, "gene_names": "Hexo1;CG1318;DmHex1;Dmel\\CG1318;Dmel_CG1318;HEX 1;HEX1;HEXO1;Hexo1", "protein_name": "beta-N-acetylhexosaminidase", "disease": [ { "disease_id": "DOID:12377", "name": "spinal muscular atrophy", "description": "A motor neuron disease that is a degenerative neuromuscular disease characterized by lower motor neuron degeneration associated with progressive muscle weakness and atrophy.", "url": "https://disease-ontology.org/term/DOID:12377", "evidence": [ { "id": "12377", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12377" } ], "weight": 0.0 }, { "disease_id": "DOID:3211", "name": "lysosomal storage disease", "description": "An inherited metabolic disorder that involve an abnormal accumulation of substances inside the lysosome resulting from defects in lysosomal function.", "url": "https://disease-ontology.org/term/DOID:3211", "evidence": [ { "id": "3211", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3211" } ], "weight": 0.0 }, { "disease_id": "DOID:3320", "name": "Tay-Sachs disease", "description": "A GM2 gangliosidosis that is characterized onset in infancy of developmental retardation, followed by paralysis, dementia and blindness, with death in the second or third year of life and has_material_basis_in homozygous or compound heterozygous mutation in the alpha subunit of the hexosaminidase A gene (HEXA) on chromosome 15q23.", "url": "https://disease-ontology.org/term/DOID:3320", "evidence": [ { "id": "3320", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3320" } ], "weight": 0.0 }, { "disease_id": "DOID:3323", "name": "Sandhoff disease", "description": "A GM2 gangliosidosis that is characterized by an accumulation of GM2 gangliosides, particularly in neurons, and that has_material_basis_in mutation in the beta subunit of hexosaminidase (HEXB) on chromosome 5q13.", "url": "https://disease-ontology.org/term/DOID:3323", "evidence": [ { "id": "3323", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3323" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q0E8H9", "url": "https://www.uniprot.org/uniprotkb/Q0E8H9" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "Q0E8H9", "url": "https://www.uniprot.org/uniprotkb/Q0E8H9" } ], "pmid": "" } ], "biological_process": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "Q0E8H9", "url": "https://www.uniprot.org/uniprotkb/Q0E8H9" } ], "pmid": "" }, { "name": "glycosaminoglycan metabolic process", "id": "GO:0030203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030203", "evidence": [ { "database": "UniProtKB", "id": "Q0E8H9", "url": "https://www.uniprot.org/uniprotkb/Q0E8H9" } ], "pmid": "" }, { "name": "chondroitin sulfate proteoglycan catabolic process", "id": "GO:0030207", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030207", "evidence": [ { "database": "UniProtKB", "id": "Q0E8H9", "url": "https://www.uniprot.org/uniprotkb/Q0E8H9" } ], "pmid": "" }, { "name": "chitin catabolic process", "id": "GO:0006032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006032", "evidence": [ { "database": "UniProtKB", "id": "Q0E8H9", "url": "https://www.uniprot.org/uniprotkb/Q0E8H9" } ], "pmid": "" }, { "name": "N-glycan processing", "id": "GO:0006491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006491", "evidence": [ { "database": "UniProtKB", "id": "Q0E8H9", "url": "https://www.uniprot.org/uniprotkb/Q0E8H9" } ], "pmid": "" }, { "name": "rhodopsin biosynthetic process", "id": "GO:0016063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016063", "evidence": [ { "database": "UniProtKB", "id": "Q0E8H9", "url": "https://www.uniprot.org/uniprotkb/Q0E8H9" } ], "pmid": "" } ], "molecular_function": [ { "name": "beta-N-acetylglucosaminidase activity", "id": "GO:0016231", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016231", "evidence": [ { "database": "UniProtKB", "id": "Q0E8H9", "url": "https://www.uniprot.org/uniprotkb/Q0E8H9" } ], "pmid": "" }, { "name": "beta-N-acetylhexosaminidase activity", "id": "GO:0004563", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004563", "evidence": [ { "database": "UniProtKB", "id": "Q0E8H9", "url": "https://www.uniprot.org/uniprotkb/Q0E8H9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q0E8H9-1", "start_pos": "144", "end_pos": "144", "site_lbl": "Thr144", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 144, "start_aa": "Thr", "end_pos": 144, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr144", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q0E8H9-1" }, { "uniprot_canonical_ac": "Q0E8V6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0E8V6", "url": "https://www.uniprot.org/uniprotkb/Q0E8V6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 384, "chemical_mass": 43396.0, "gene_names": "Spn28Da;CG12318;CG31902;Dmel\\CG31902;Dmel_CG31902;Spn28Da", "protein_name": "", "disease": [ { "disease_id": "DOID:0050589", "name": "inflammatory bowel disease", "description": "An intestinal disease characterized by inflammation located in all parts of digestive tract.", "url": "https://disease-ontology.org/term/DOID:0050589", "evidence": [ { "id": "0050589", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050589" } ], "weight": 0.0 }, { "disease_id": "DOID:0050831", "name": "familial encephalopathy with neuroserpin inclusion bodies", "description": "A neurodegenerative disease that is characterized by intraneuronal inclusions of mutant neuroserpin resulting in progressive encephalopathy, dementia and seizures and has_material_basis_in a mutation in the SERPINI1 gene inherited in an in autosomal dominant pattern.", "url": "https://disease-ontology.org/term/DOID:0050831", "evidence": [ { "id": "0050831", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050831" } ], "weight": 0.0 }, { "disease_id": "DOID:0051054", "name": "coarctation of the aorta", "description": "A congenital heart disease that is characterized by the luminal narrowing of the thoracic aortic arch, typically located just beyond the left subclavian artery. This narrowing creates an obstruction that can lead to significant cardiovascular complications, including systemic hypertension, left ventricular hypertrophy, and eventually heart failure.", "url": "https://disease-ontology.org/term/DOID:0051054", "evidence": [ { "id": "0051054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051054" } ], "weight": 0.0 }, { "disease_id": "DOID:0051061", "name": "stroke", "description": "A cerebrovascular disease that is characterized by disruption of blood flow to the brain resulting in damage to brain cells due to a lack of oxygen.", "url": "https://disease-ontology.org/term/DOID:0051061", "evidence": [ { "id": "0051061", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051061" } ], "weight": 0.0 }, { "disease_id": "DOID:0060186", "name": "chemical colitis", "description": "A colitis caused_by introduction of various chemicals.", "url": "https://disease-ontology.org/term/DOID:0060186", "evidence": [ { "id": "0060186", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060186" } ], "weight": 0.0 }, { "disease_id": "DOID:0060189", "name": "ileitis", "description": "An inflammatory bowel disease characterized by inflammation located_in ileum, has_symptom diarrhea, has_symptom abdominal pain, often in the right lower quadrant, has_symptom weight loss.", "url": "https://disease-ontology.org/term/DOID:0060189", "evidence": [ { "id": "0060189", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060189" } ], "weight": 0.0 }, { "disease_id": "DOID:0060224", "name": "atrial fibrillation", "description": "A heart conduction disease that is characterized by uncoordinated electrical activity in the heart's upper chambers (the atria), which causes the heartbeat to become fast and irregular and has symptoms palpitations, weakness, fatigue, lightheadedness, dizziness, confusion, shortness of breath and chest pain.", "url": "https://disease-ontology.org/term/DOID:0060224", "evidence": [ { "id": "0060224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060224" } ], "weight": 0.0 }, { "disease_id": "DOID:0060903", "name": "thrombosis", "description": "A vascular disease caused by the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system.", "url": "https://disease-ontology.org/term/DOID:0060903", "evidence": [ { "id": "0060903", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060903" } ], "weight": 0.0 }, { "disease_id": "DOID:0070508", "name": "metabolic dysfunction and alcohol associated liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and elevated alcohol consumption. This disease is distinguished from MASLD by increased alcohol consumption and from ALD by the evidence of one or more of the specified cardiometabolic risk factors. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0070508", "evidence": [ { "id": "0070508", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070508" } ], "weight": 0.0 }, { "disease_id": "DOID:0070555", "name": "Nagashima-type palmoplantar keratosis", "description": "A nonepidermolytic palmoplantar keratoderma characterized by mild, well-demarcated, diffuse erythematous hyperkeratosis that is nonprogressive after the second decade of life which extends onto the dorsal surfaces of the palms and feet and the Achilles tendon area, with a high frequency of hyperhidrosis on the palms and soles and without flexion contractures or constricting bands that has_material_basis_in homozygous or compound heterozygous mutation in the SERPINB7 gene on chromosome 18q21.33.", "url": "https://disease-ontology.org/term/DOID:0070555", "evidence": [ { "id": "0070555", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070555" } ], "weight": 0.0 }, { "disease_id": "DOID:0080322", "name": "polycystic kidney disease", "description": "A cystic kidney disease that is characterized by the growth of fluid-filled cysts in the kidneys that reduces kidney function and may lead to kidney failure.", "url": "https://disease-ontology.org/term/DOID:0080322", "evidence": [ { "id": "0080322", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080322" } ], "weight": 0.0 }, { "disease_id": "DOID:0090030", "name": "corticosteroid-binding globulin deficiency", "description": "An adrenal gland disease characterized by decreased levels of serum corticosteroid-binding globulin and cortisol, and in some cases hypo- or hypertension, and muscle fatigue that has_material_basis_in heterozygous or homozygous mutation in the SERPINA6 gene on chromosome 14q32.", "url": "https://disease-ontology.org/term/DOID:0090030", "evidence": [ { "id": "0090030", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090030" } ], "weight": 0.0 }, { "disease_id": "DOID:10159", "name": "osteonecrosis", "description": "An ischemic bone disease that results_in necrosis located_in bone.", "url": "https://disease-ontology.org/term/DOID:10159", "evidence": [ { "id": "10159", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10159" } ], "weight": 0.0 }, { "disease_id": "DOID:10591", "name": "pre-eclampsia", "description": "A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy.", "url": "https://disease-ontology.org/term/DOID:10591", "evidence": [ { "id": "10591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10591" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:10762", "name": "portal hypertension", "description": "", "url": "https://disease-ontology.org/term/DOID:10762", "evidence": [ { "id": "10762", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10762" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10808", "name": "gastric ulcer", "description": "", "url": "https://disease-ontology.org/term/DOID:10808", "evidence": [ { "id": "10808", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10808" } ], "weight": 0.0 }, { "disease_id": "DOID:10952", "name": "nephritis", "description": "A kidney disease that is characterized by an inflammation of the kidneys.", "url": "https://disease-ontology.org/term/DOID:10952", "evidence": [ { "id": "10952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10952" } ], "weight": 0.0 }, { "disease_id": "DOID:11049", "name": "meconium aspiration syndrome", "description": "A lung disease that is characterized by a newborn breathing in a mixture of meconium and amniotic fluid into the lungs around the time of delivery.", "url": "https://disease-ontology.org/term/DOID:11049", "evidence": [ { "id": "11049", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11049" } ], "weight": 0.0 }, { "disease_id": "DOID:11111", "name": "hydronephrosis", "description": "An urinary system disease that is characterized by swelling of one or both kidneys due to incomplete voiding of urine.", "url": "https://disease-ontology.org/term/DOID:11111", "evidence": [ { "id": "11111", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11111" } ], "weight": 0.0 }, { "disease_id": "DOID:11123", "name": "IgA vasculitis", "description": "A hypersensitivity vasculitis that is characterized by purpura (purplish plaques), arthralgia, gastrointestinal upset, and/or glomerulonephritis, and may be related to increased immune response following an infection.", "url": "https://disease-ontology.org/term/DOID:11123", "evidence": [ { "id": "11123", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11123" } ], "weight": 0.0 }, { "disease_id": "DOID:11247", "name": "disseminated intravascular coagulation", "description": "", "url": "https://disease-ontology.org/term/DOID:11247", "evidence": [ { "id": "11247", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11247" } ], "weight": 0.0 }, { "disease_id": "DOID:11394", "name": "adult respiratory distress syndrome", "description": "A respiratory failure that results from diffuse injury to the endothelium of the lung (as in sepsis, chest trauma, massive blood transfusion, aspiration of the gastric contents, or pneumonia) and is characterized by pulmonary edema with an abnormally high amount of protein in the edematous fluid and by difficult rapid breathing and hypoxemia.", "url": "https://disease-ontology.org/term/DOID:11394", "evidence": [ { "id": "11394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11394" } ], "weight": 0.0 }, { "disease_id": "DOID:11396", "name": "pulmonary edema", "description": "A respiratory failure that is characterized by the accumulation of fluid in the lung tissues causing disturbance of the gas exchange that may lead to respiratory failure.", "url": "https://disease-ontology.org/term/DOID:11396", "evidence": [ { "id": "11396", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11396" } ], "weight": 0.0 }, { "disease_id": "DOID:11446", "name": "sciatic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:11446", "evidence": [ { "id": "11446", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11446" } ], "weight": 0.0 }, { "disease_id": "DOID:11716", "name": "prediabetes syndrome", "description": "A glucose metabolism disease that is characterized by blood glucose levels are high, but not high enough to be classified as type 2 diabetes.", "url": "https://disease-ontology.org/term/DOID:11716", "evidence": [ { "id": "11716", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11716" } ], "weight": 0.0 }, { "disease_id": "DOID:1184", "name": "nephrotic syndrome", "description": "A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.", "url": "https://disease-ontology.org/term/DOID:1184", "evidence": [ { "id": "1184", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1184" } ], "weight": 0.0 }, { "disease_id": "DOID:11949", "name": "Creutzfeldt-Jakob disease", "description": "", "url": "https://disease-ontology.org/term/DOID:11949", "evidence": [ { "id": "11949", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11949" } ], "weight": 0.0 }, { "disease_id": "DOID:11984", "name": "hypertrophic cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause.", "url": "https://disease-ontology.org/term/DOID:11984", "evidence": [ { "id": "11984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11984" } ], "weight": 0.0 }, { "disease_id": "DOID:1205", "name": "allergic disease", "description": "An immune system disease that is an exaggerated immune response to allergens, such as insect venom, dust mites, pollen, pet dander, drugs or some foods.", "url": "https://disease-ontology.org/term/DOID:1205", "evidence": [ { "id": "1205", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1205" } ], "weight": 0.0 }, { "disease_id": "DOID:12185", "name": "otosclerosis", "description": "An otitis interna characterized by isolated endochondral bone sclerosis of the labyrinthine capsule.", "url": "https://disease-ontology.org/term/DOID:12185", "evidence": [ { "id": "12185", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12185" } ], "weight": 0.0 }, { "disease_id": "DOID:12236", "name": "primary biliary cholangitis", "description": "A liver cirrhosis characterized by chronic and slow progressive destruction of intrahepatic bile ducts.", "url": "https://disease-ontology.org/term/DOID:12236", "evidence": [ { "id": "12236", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12236" } ], "weight": 0.0 }, { "disease_id": "DOID:12351", "name": "alcoholic hepatitis", "description": "", "url": "https://disease-ontology.org/term/DOID:12351", "evidence": [ { "id": "12351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12351" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:13025", "name": "retinopathy of prematurity", "description": "", "url": "https://disease-ontology.org/term/DOID:13025", "evidence": [ { "id": "13025", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13025" } ], "weight": 0.0 }, { "disease_id": "DOID:1312", "name": "focal segmental glomerulosclerosis", "description": "", "url": "https://disease-ontology.org/term/DOID:1312", "evidence": [ { "id": "1312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1312" } ], "weight": 0.0 }, { "disease_id": "DOID:13141", "name": "uveitis", "description": "An uveal disease is characterized by inflammation of any of the layers of the uvea of the eye, which includes the iris, ciliary body, and choroid.", "url": "https://disease-ontology.org/term/DOID:13141", "evidence": [ { "id": "13141", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13141" } ], "weight": 0.0 }, { "disease_id": "DOID:13372", "name": "alpha 1-antitrypsin deficiency", "description": "A plasma protein metabolism disease that has_material_basis_in defective production of the protease inhibitor alpha 1-antitrypsin (A1AT), leading to decreased A1AT activity in the blood and lungs, and deposition of excessive abnormal A1AT protein in liver cells.", "url": "https://disease-ontology.org/term/DOID:13372", "evidence": [ { "id": "13372", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13372" } ], "weight": 0.0 }, { "disease_id": "DOID:13884", "name": "sick sinus syndrome", "description": "", "url": "https://disease-ontology.org/term/DOID:13884", "evidence": [ { "id": "13884", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13884" } ], "weight": 0.0 }, { "disease_id": "DOID:14115", "name": "toxic shock syndrome", "description": "A commensal bacterial infectious disease that results_in infection, has_material_basis_in Streptococcus pyogenes or has_material_basis_in Staphylococcus aureus, which produce toxins that are absorbed systemically and produce the systemic manifestations. The infection has_symptom fever, has_symptom rash, has_symptom hypotension, has_symptom multiorgan failure, has_symptom desquamation, has_symptom vomiting, has_symptom diarrhea, has_symptom headache, and has_symptom nonfocal neurologic abnormalities.", "url": "https://disease-ontology.org/term/DOID:14115", "evidence": [ { "id": "14115", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14115" } ], "weight": 0.0 }, { "disease_id": "DOID:14499", "name": "Fabry disease", "description": "A sphingolipidosis that is characterized by the buildup of globotriaosylceramide in the body's cells and has_material_basis_in X-linked inherited mutations in the GLA gene, encoding alpha-galactosidase A, on chromosome Xq22.", "url": "https://disease-ontology.org/term/DOID:14499", "evidence": [ { "id": "14499", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14499" } ], "weight": 0.0 }, { "disease_id": "DOID:1485", "name": "cystic fibrosis", "description": "A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs.", "url": "https://disease-ontology.org/term/DOID:1485", "evidence": [ { "id": "1485", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1485" } ], "weight": 0.0 }, { "disease_id": "DOID:1580", "name": "diffuse scleroderma", "description": "", "url": "https://disease-ontology.org/term/DOID:1580", "evidence": [ { "id": "1580", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1580" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:1875", "name": "impotence", "description": "A sexual dysfunction that is characterized by persistent or recurrent inability to achieve or to maintain an erection during sexual activity.", "url": "https://disease-ontology.org/term/DOID:1875", "evidence": [ { "id": "1875", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1875" } ], "weight": 0.0 }, { "disease_id": "DOID:1936", "name": "atherosclerosis", "description": "An arteriosclerotic cardiovascular disease that is characterized by the build-up of fatty material and calcium deposition in the arterial wall resulting in partial or complete occlusion of the arterial lumen. Disease is located within the tunica intima of large and small arteries.", "url": "https://disease-ontology.org/term/DOID:1936", "evidence": [ { "id": "1936", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1936" } ], "weight": 0.0 }, { "disease_id": "DOID:2018", "name": "hyperinsulinism", "description": "", "url": "https://disease-ontology.org/term/DOID:2018", "evidence": [ { "id": "2018", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2018" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:2349", "name": "arteriosclerosis", "description": "An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries.", "url": "https://disease-ontology.org/term/DOID:2349", "evidence": [ { "id": "2349", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2349" } ], "weight": 0.0 }, { "disease_id": "DOID:2377", "name": "multiple sclerosis", "description": "A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring.", "url": "https://disease-ontology.org/term/DOID:2377", "evidence": [ { "id": "2377", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2377" } ], "weight": 0.0 }, { "disease_id": "DOID:2450", "name": "central retinal vein occlusion", "description": "", "url": "https://disease-ontology.org/term/DOID:2450", "evidence": [ { "id": "2450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2450" } ], "weight": 0.0 }, { "disease_id": "DOID:289", "name": "endometriosis", "description": "A female reproductive system disease characterized by the growth of endometrial tissue outside the uterine body.", "url": "https://disease-ontology.org/term/DOID:289", "evidence": [ { "id": "289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:289" } ], "weight": 0.0 }, { "disease_id": "DOID:2913", "name": "acute pancreatitis", "description": "A pancreatitis that is characterized by inflammation of the pancreas over a short period of time and has symptoms of severe abdominal pain, nausea, vomiting, diarrhea, fever, and shock.", "url": "https://disease-ontology.org/term/DOID:2913", "evidence": [ { "id": "2913", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2913" } ], "weight": 0.0 }, { "disease_id": "DOID:2921", "name": "glomerulonephritis", "description": "A nephritis that causes inflammation of the glomeruli located_in kidney.", "url": "https://disease-ontology.org/term/DOID:2921", "evidence": [ { "id": "2921", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2921" } ], "weight": 0.0 }, { "disease_id": "DOID:2945", "name": "severe acute respiratory syndrome", "description": "A Coronavirus infectious disease that results_in infection located_in respiratory tract, has_material_basis_in Severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1), a subtype of Betacoronavirus pandemicum, which is transmitted_by droplet spread of respiratory secretions, transmitted_by ingestion of contaminated food, or transmitted_by fomites. The infection has_symptom fever, has_symptom headache, has_symptom body aches, has_symptom dry cough, and has_symptom hypoxia.", "url": "https://disease-ontology.org/term/DOID:2945", "evidence": [ { "id": "2945", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2945" } ], "weight": 0.0 }, { "disease_id": "DOID:2986", "name": "IgA glomerulonephritis", "description": "A glomerulonephritis characterized by build up of IgA antibody in the glomerulus.", "url": "https://disease-ontology.org/term/DOID:2986", "evidence": [ { "id": "2986", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2986" } ], "weight": 0.0 }, { "disease_id": "DOID:3021", "name": "acute kidney failure", "description": "", "url": "https://disease-ontology.org/term/DOID:3021", "evidence": [ { "id": "3021", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3021" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:3328", "name": "temporal lobe epilepsy", "description": "A focal epilepsy that is characterized by recurrent, unprovoked focal seizures that originate in the temporal lobe of the brain and last about one or two minutes.", "url": "https://disease-ontology.org/term/DOID:3328", "evidence": [ { "id": "3328", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3328" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:3407", "name": "carotid artery disease", "description": "", "url": "https://disease-ontology.org/term/DOID:3407", "evidence": [ { "id": "3407", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3407" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 }, { "disease_id": "DOID:3587", "name": "pancreatic ductal carcinoma", "description": "A pancreatic carcinoma located_in the pancreatic duct.", "url": "https://disease-ontology.org/term/DOID:3587", "evidence": [ { "id": "3587", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3587" } ], "weight": 0.0 }, { "disease_id": "DOID:3755", "name": "antithrombin III deficiency", "description": "A thrombophilia that is characterized by the tendency to form clots in the veins.", "url": "https://disease-ontology.org/term/DOID:3755", "evidence": [ { "id": "3755", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3755" } ], "weight": 0.0 }, { "disease_id": "DOID:3770", "name": "pulmonary fibrosis", "description": "An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation. It can be caused by inhaling hazardous chemicals, certain diseases, medication and genetics or unknown causes.", "url": "https://disease-ontology.org/term/DOID:3770", "evidence": [ { "id": "3770", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3770" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:409", "name": "liver disease", "description": "", "url": "https://disease-ontology.org/term/DOID:409", "evidence": [ { "id": "409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:409" } ], "weight": 0.0 }, { "disease_id": "DOID:418", "name": "systemic scleroderma", "description": "A scleroderma that is characterized by fibrosis (or hardening) of the skin and major organs, as well as vascular alterations, and autoantibodies.", "url": "https://disease-ontology.org/term/DOID:418", "evidence": [ { "id": "418", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:418" } ], "weight": 0.0 }, { "disease_id": "DOID:4448", "name": "macular degeneration", "description": "A retinal degeneration characterized by gradual deterioration of light-sensing cells in the tissues at the back of the eye and has_symptom vision loss.", "url": "https://disease-ontology.org/term/DOID:4448", "evidence": [ { "id": "4448", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4448" } ], "weight": 0.0 }, { "disease_id": "DOID:4780", "name": "anti-basement membrane glomerulonephritis", "description": "A Goodpasture syndrome that is characterized by damage to only kidney capillaries.", "url": "https://disease-ontology.org/term/DOID:4780", "evidence": [ { "id": "4780", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4780" } ], "weight": 0.0 }, { "disease_id": "DOID:5082", "name": "liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:5082", "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ], "weight": 0.0 }, { "disease_id": "DOID:526", "name": "human immunodeficiency virus infectious disease", "description": "A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.", "url": "https://disease-ontology.org/term/DOID:526", "evidence": [ { "id": "526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:526" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 }, { "disease_id": "DOID:6713", "name": "cerebrovascular disease", "description": "An vascular disease that is characterized by dysfunction of the blood vessels supplying the brain.", "url": "https://disease-ontology.org/term/DOID:6713", "evidence": [ { "id": "6713", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6713" } ], "weight": 0.0 }, { "disease_id": "DOID:8398", "name": "osteoarthritis", "description": "An arthritis that has_material_basis_in worn out cartilage located_in joint.", "url": "https://disease-ontology.org/term/DOID:8398", "evidence": [ { "id": "8398", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8398" } ], "weight": 0.0 }, { "disease_id": "DOID:8552", "name": "chronic myeloid leukemia", "description": "A myeloid leukemia that is characterized by over production of white blood cells.", "url": "https://disease-ontology.org/term/DOID:8552", "evidence": [ { "id": "8552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8552" } ], "weight": 0.0 }, { "disease_id": "DOID:865", "name": "vasculitis", "description": "A vascular disease that is characterized by inflammation of the blood vessels.", "url": "https://disease-ontology.org/term/DOID:865", "evidence": [ { "id": "865", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:865" } ], "weight": 0.0 }, { "disease_id": "DOID:8805", "name": "intermediate coronary syndrome", "description": "", "url": "https://disease-ontology.org/term/DOID:8805", "evidence": [ { "id": "8805", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8805" } ], "weight": 0.0 }, { "disease_id": "DOID:8923", "name": "skin melanoma", "description": "A skin cancer that has_material_basis_in melanocytes.", "url": "https://disease-ontology.org/term/DOID:8923", "evidence": [ { "id": "8923", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8923" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9675", "name": "pulmonary emphysema", "description": "A chronic obstructive pulmonary disease that is characterized by permanent enlargement of air spaces distal to the terminal bronchioles and the destruction of the alveolar walls.", "url": "https://disease-ontology.org/term/DOID:9675", "evidence": [ { "id": "9675", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9675" } ], "weight": 0.0 }, { "disease_id": "DOID:988", "name": "mitral valve prolapse", "description": "A mitral valve disease where one or both of the cusps of the mitral valve bulge or collapse backward in the left atrium during systole.", "url": "https://disease-ontology.org/term/DOID:988", "evidence": [ { "id": "988", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:988" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "Q0E8V6", "url": "https://www.uniprot.org/uniprotkb/Q0E8V6" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q0E8V6", "url": "https://www.uniprot.org/uniprotkb/Q0E8V6" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of proteolysis", "id": "GO:0045861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045861", "evidence": [ { "database": "UniProtKB", "id": "Q0E8V6", "url": "https://www.uniprot.org/uniprotkb/Q0E8V6" } ], "pmid": "" }, { "name": "mating", "id": "GO:0007618", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007618", "evidence": [ { "database": "UniProtKB", "id": "Q0E8V6", "url": "https://www.uniprot.org/uniprotkb/Q0E8V6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q0E8V6-1" }, { "uniprot_canonical_ac": "Q0E9B1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0E9B1", "url": "https://www.uniprot.org/uniprotkb/Q0E9B1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 180, "chemical_mass": 21484.0, "gene_names": "CR33632;CG33632;CR33632;Dmel\\CG33632;Dmel_CG33632", "protein_name": "MD-2-related lipid-recognition domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q0E9B1-1" }, { "uniprot_canonical_ac": "Q0KI05-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0KI05", "url": "https://www.uniprot.org/uniprotkb/Q0KI05" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 4842, "chemical_mass": 553527.0, "gene_names": "Dmel\\CG3339;CG3339;DHC5;Dmel\\CG3339;Dmel_CG3339", "protein_name": "", "disease": [ { "disease_id": "DOID:0050144", "name": "Kartagener syndrome", "description": "A primary ciliary dyskinesia that is characterized by sinusitis, bronchiectasis and situs inversus with dextrocardia resulting from dysfunction of the cilia during embryologic development.", "url": "https://disease-ontology.org/term/DOID:0050144", "evidence": [ { "id": "0050144", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050144" } ], "weight": 0.0 }, { "disease_id": "DOID:0110605", "name": "primary ciliary dyskinesia 7", "description": "A primary ciliary dyskinesia that is characterized by autosomal recessive inheritance with chronic respiratory infections, chronic sinusitis, recurrent bronchitis, and pneumonia beginning in infancy or early childhood and has_material_basis_in mutation in the DNAH11 gene on chromosome 7p21.", "url": "https://disease-ontology.org/term/DOID:0110605", "evidence": [ { "id": "0110605", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110605" } ], "weight": 0.0 }, { "disease_id": "DOID:0111853", "name": "primary ciliary dyskinesia 40", "description": "A primary ciliary dyskinesia characterized by a subtle defect in the bend of the distal portion of the cilia, reduced ciliary clearance in-vitro, relatively mild respiratory phenotype and laterality defects in all reported patients that has_material_basis_in homozygous or compound heterozygous mutation in the DNAH9 gene on chromosome 17p12.", "url": "https://disease-ontology.org/term/DOID:0111853", "evidence": [ { "id": "0111853", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111853" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cilium movement involved in cell motility", "id": "GO:0060294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060294", "evidence": [ { "database": "UniProtKB", "id": "Q0KI05", "url": "https://www.uniprot.org/uniprotkb/Q0KI05" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q0KI05", "url": "https://www.uniprot.org/uniprotkb/Q0KI05" } ], "pmid": "" }, { "name": "minus-end-directed microtubule motor activity", "id": "GO:0008569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008569", "evidence": [ { "database": "UniProtKB", "id": "Q0KI05", "url": "https://www.uniprot.org/uniprotkb/Q0KI05" } ], "pmid": "" }, { "name": "dynein light intermediate chain binding", "id": "GO:0051959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051959", "evidence": [ { "database": "UniProtKB", "id": "Q0KI05", "url": "https://www.uniprot.org/uniprotkb/Q0KI05" } ], "pmid": "" }, { "name": "dynein intermediate chain binding", "id": "GO:0045505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045505", "evidence": [ { "database": "UniProtKB", "id": "Q0KI05", "url": "https://www.uniprot.org/uniprotkb/Q0KI05" } ], "pmid": "" } ], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q0KI05", "url": "https://www.uniprot.org/uniprotkb/Q0KI05" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "Q0KI05", "url": "https://www.uniprot.org/uniprotkb/Q0KI05" } ], "pmid": "" }, { "name": "dynein complex", "id": "GO:0030286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030286", "evidence": [ { "database": "UniProtKB", "id": "Q0KI05", "url": "https://www.uniprot.org/uniprotkb/Q0KI05" } ], "pmid": "" }, { "name": "outer dynein arm", "id": "GO:0036157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036157", "evidence": [ { "database": "UniProtKB", "id": "Q0KI05", "url": "https://www.uniprot.org/uniprotkb/Q0KI05" } ], "pmid": "" }, { "name": "9+2 motile cilium", "id": "GO:0097729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097729", "evidence": [ { "database": "UniProtKB", "id": "Q0KI05", "url": "https://www.uniprot.org/uniprotkb/Q0KI05" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q0KI05-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Thr135", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 135, "start_aa": "Thr", "end_pos": 135, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr135", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q0KI05-1" }, { "uniprot_canonical_ac": "Q0KI25-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0KI25", "url": "https://www.uniprot.org/uniprotkb/Q0KI25" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1125, "chemical_mass": 126543.0, "gene_names": "CG13825;Dmel\\CG4467;CG13825;CG4467;Dmel\\CG4467;Dmel_CG4467", "protein_name": "Endoplasmic reticulum aminopeptidase 2", "disease": [ { "disease_id": "DOID:127", "name": "leiomyoma", "description": "A cell type benign neoplasm that is a benign tumor of smooth muscle cells.", "url": "https://disease-ontology.org/term/DOID:127", "evidence": [ { "id": "127", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:127" } ], "weight": 0.0 }, { "disease_id": "DOID:13129", "name": "severe pre-eclampsia", "description": "A pre-eclampsia that has_symptom at least one of the following: SBP of 160mm HG or higher or DPB of 110mm HG or higher on 2 occasions at least 6 hours apart, proteinuria more than 5g in a 24-hour collection, pulmonary edema or cyanosis, oliguria, persistent headaches, epigastric pain and/or impaired liver function, thrombocytopenia, oligohydramnios, decreased fetal growth or placental abruption.", "url": "https://disease-ontology.org/term/DOID:13129", "evidence": [ { "id": "13129", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13129" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:2871", "name": "endometrial carcinoma", "description": "A endometrial cancer that is located_in the tissue lining the uterus.", "url": "https://disease-ontology.org/term/DOID:2871", "evidence": [ { "id": "2871", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2871" } ], "weight": 0.0 }, { "disease_id": "DOID:2893", "name": "cervix carcinoma", "description": "A cervical cancer that is located_in the cervix uteri or located_in the cervical area and that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:2893", "evidence": [ { "id": "2893", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2893" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:8488", "name": "polyhydramnios", "description": "A placenta disease that is characterized by an excess of amniotic fluid in the amniotic sac.", "url": "https://disease-ontology.org/term/DOID:8488", "evidence": [ { "id": "8488", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8488" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q0KI25", "url": "https://www.uniprot.org/uniprotkb/Q0KI25" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q0KI25", "url": "https://www.uniprot.org/uniprotkb/Q0KI25" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q0KI25", "url": "https://www.uniprot.org/uniprotkb/Q0KI25" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q0KI25", "url": "https://www.uniprot.org/uniprotkb/Q0KI25" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q0KI25-1" }, { "uniprot_canonical_ac": "Q0KI77-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0KI77", "url": "https://www.uniprot.org/uniprotkb/Q0KI77" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 388, "chemical_mass": 43792.0, "gene_names": "Dmel\\CG11598;CG11598;Dmel\\CG11598;Dmel_CG11598", "protein_name": "Lipase", "disease": [ { "disease_id": "DOID:0080217", "name": "lysosomal acid lipase deficiency", "description": "A lipid storage disease characterized by dyslipidemia and accumulation of cholesteryl esters and triglycerides within various organs that has_material_basis_in homozygous or compound heterozygous mutation in the LIPA gene on chromosome 10q23.31.", "url": "https://disease-ontology.org/term/DOID:0080217", "evidence": [ { "id": "0080217", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080217" } ], "weight": 0.0 }, { "disease_id": "DOID:14497", "name": "Wolman disease", "description": "A lysosomal acid lipase deficiency characterized by infantile onset of rapidly progressive accumulation of cholesteryl esters and triglycerides throughout the body, resulting in hepatosplenomegaly, severe malnutrition, jaundice, vomiting, diarrhea, steatorrhea. Death usually occurs within the first year of life.", "url": "https://disease-ontology.org/term/DOID:14497", "evidence": [ { "id": "14497", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14497" } ], "weight": 0.0 } ], "biological_process": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "Q0KI77", "url": "https://www.uniprot.org/uniprotkb/Q0KI77" } ], "pmid": "" }, { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "Q0KI77", "url": "https://www.uniprot.org/uniprotkb/Q0KI77" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "Q0KI77", "url": "https://www.uniprot.org/uniprotkb/Q0KI77" } ], "pmid": "" }, { "name": "mating", "id": "GO:0007618", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007618", "evidence": [ { "database": "UniProtKB", "id": "Q0KI77", "url": "https://www.uniprot.org/uniprotkb/Q0KI77" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q0KI77", "url": "https://www.uniprot.org/uniprotkb/Q0KI77" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipase activity", "id": "GO:0016298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016298", "evidence": [ { "database": "UniProtKB", "id": "Q0KI77", "url": "https://www.uniprot.org/uniprotkb/Q0KI77" } ], "pmid": "" }, { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "Q0KI77", "url": "https://www.uniprot.org/uniprotkb/Q0KI77" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q0KI77-1" }, { "uniprot_canonical_ac": "Q0KI91-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0KI91", "url": "https://www.uniprot.org/uniprotkb/Q0KI91" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 171, "chemical_mass": 19937.0, "gene_names": "Dmel\\CG12817;BcDNA:RE53107;CG12817;Dmel\\CG12817;Dmel_CG12817", "protein_name": "EF-hand domain-containing protein", "disease": [], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q0KI91", "url": "https://www.uniprot.org/uniprotkb/Q0KI91" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q0KI91-1" }, { "uniprot_canonical_ac": "Q2MGK5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q2MGK5", "url": "https://www.uniprot.org/uniprotkb/Q2MGK5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 690, "chemical_mass": 79235.0, "gene_names": "Dmel\\CG4970;CG32953;CG4970;Dmel\\CG4970;Dmel_CG4970;anon-WO0140519.184", "protein_name": "CCDC113/CCDC96 coiled-coil domain-containing protein", "disease": [], "biological_process": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "Q2MGK5", "url": "https://www.uniprot.org/uniprotkb/Q2MGK5" } ], "pmid": "" } ], "cellular_component": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "Q2MGK5", "url": "https://www.uniprot.org/uniprotkb/Q2MGK5" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "Q2MGK5", "url": "https://www.uniprot.org/uniprotkb/Q2MGK5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q2MGK5-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Ser107", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 107, "start_aa": "Ser", "end_pos": 107, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser107", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q2MGK5", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q2MGK5" } ] } ] }, { "uniprot_canonical_ac": "Q2MGK5-1", "start_pos": "406", "end_pos": "406", "site_lbl": "Thr406", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 406, "start_aa": "Thr", "end_pos": 406, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr406", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q2MGK5-1" }, { "uniprot_canonical_ac": "Q2MGL5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q2MGL5", "url": "https://www.uniprot.org/uniprotkb/Q2MGL5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 180, "chemical_mass": 21422.0, "gene_names": "Dmel\\CG33764;CG33764;Dmel\\CG33764;Dmel_CG33764", "protein_name": "MD-2-related lipid-recognition domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q2MGL5-1" }, { "uniprot_canonical_ac": "Q2MGL8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q2MGL8", "url": "https://www.uniprot.org/uniprotkb/Q2MGL8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 310, "chemical_mass": 35801.0, "gene_names": "Dmel\\CG33966;CG1211;CG33966;Dmel\\CG33966;Dmel_CG33966", "protein_name": "CRAL-TRIO domain-containing protein", "disease": [], "molecular_function": [ { "name": "phosphatidylinositol bisphosphate binding", "id": "GO:1902936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902936", "evidence": [ { "database": "UniProtKB", "id": "Q2MGL8", "url": "https://www.uniprot.org/uniprotkb/Q2MGL8" } ], "pmid": "" }, { "name": "lipid transfer activity", "id": "GO:0120013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120013", "evidence": [ { "database": "UniProtKB", "id": "Q2MGL8", "url": "https://www.uniprot.org/uniprotkb/Q2MGL8" } ], "pmid": "" } ], "cellular_component": [ { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "Q2MGL8", "url": "https://www.uniprot.org/uniprotkb/Q2MGL8" } ], "pmid": "" } ], "biological_process": [ { "name": "intermembrane lipid transfer", "id": "GO:0120009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120009", "evidence": [ { "database": "UniProtKB", "id": "Q2MGL8", "url": "https://www.uniprot.org/uniprotkb/Q2MGL8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q2MGL8-1" }, { "uniprot_canonical_ac": "Q2MGP2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q2MGP2", "url": "https://www.uniprot.org/uniprotkb/Q2MGP2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 160, "chemical_mass": 18734.0, "gene_names": "Dmel\\CG33665;CG33665;Dmel\\CG33665;Dmel_CG33665", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q2MGP2-1" }, { "uniprot_canonical_ac": "Q2MGP7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q2MGP7", "url": "https://www.uniprot.org/uniprotkb/Q2MGP7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 160, "chemical_mass": 18712.0, "gene_names": "Dmel\\CG33664;CG33664;Dmel\\CG33664;Dmel_CG33664", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q2MGP7-1" }, { "uniprot_canonical_ac": "Q2PE06-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q2PE06", "url": "https://www.uniprot.org/uniprotkb/Q2PE06" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 325, "chemical_mass": 37660.0, "gene_names": "Dmel\\CG34025;BP1082;CG34025;Dmel\\CG34025;Dmel_CG34025;HDC08169", "protein_name": "F-box domain-containing protein", "disease": [], "cellular_component": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "Q2PE06", "url": "https://www.uniprot.org/uniprotkb/Q2PE06" } ], "pmid": "" } ], "biological_process": [ { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "Q2PE06", "url": "https://www.uniprot.org/uniprotkb/Q2PE06" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q2PE06-1" }, { "uniprot_canonical_ac": "Q2PE19-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q2PE19", "url": "https://www.uniprot.org/uniprotkb/Q2PE19" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 281, "chemical_mass": 30356.0, "gene_names": "BP1015;BP1015;CG34040;Dmel\\CG34040;Dmel_CG34040", "protein_name": "DUF753 domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q2PE19-1", "start_pos": "208", "end_pos": "208", "site_lbl": "Thr208", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 208, "start_aa": "Thr", "end_pos": 208, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr208", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q2PE19-1" }, { "uniprot_canonical_ac": "Q4AB27-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q4AB27", "url": "https://www.uniprot.org/uniprotkb/Q4AB27" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1288, "chemical_mass": 148074.0, "gene_names": "Myo95E;95E;CG31134;CG31135;CG5501;Dm95E;DmAE003746;Dmel\\CG5501;Dmel_CG5501;Myo5;Myo95E;myo 95E", "protein_name": "", "disease": [ { "disease_id": "DOID:10003", "name": "sensorineural hearing loss", "description": "An inner ear disease that is characterized by hearing loss resulting from damage to the cochlea, auditory nerve and/or brainstem.", "url": "https://disease-ontology.org/term/DOID:10003", "evidence": [ { "id": "10003", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10003" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "Q4AB27", "url": "https://www.uniprot.org/uniprotkb/Q4AB27" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q4AB27", "url": "https://www.uniprot.org/uniprotkb/Q4AB27" } ], "pmid": "" }, { "name": "microfilament motor activity", "id": "GO:0000146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000146", "evidence": [ { "database": "UniProtKB", "id": "Q4AB27", "url": "https://www.uniprot.org/uniprotkb/Q4AB27" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "Q4AB27", "url": "https://www.uniprot.org/uniprotkb/Q4AB27" } ], "pmid": "" } ], "cellular_component": [ { "name": "myosin complex", "id": "GO:0016459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016459", "evidence": [ { "database": "UniProtKB", "id": "Q4AB27", "url": "https://www.uniprot.org/uniprotkb/Q4AB27" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q4AB27", "url": "https://www.uniprot.org/uniprotkb/Q4AB27" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q4AB27", "url": "https://www.uniprot.org/uniprotkb/Q4AB27" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "Q4AB27", "url": "https://www.uniprot.org/uniprotkb/Q4AB27" } ], "pmid": "" }, { "name": "microvillus", "id": "GO:0005902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005902", "evidence": [ { "database": "UniProtKB", "id": "Q4AB27", "url": "https://www.uniprot.org/uniprotkb/Q4AB27" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "Q4AB27", "url": "https://www.uniprot.org/uniprotkb/Q4AB27" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "Q4AB27", "url": "https://www.uniprot.org/uniprotkb/Q4AB27" } ], "pmid": "" }, { "name": "actin filament-based movement", "id": "GO:0030048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030048", "evidence": [ { "database": "UniProtKB", "id": "Q4AB27", "url": "https://www.uniprot.org/uniprotkb/Q4AB27" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q4AB27-1", "start_pos": "374", "end_pos": "374", "site_lbl": "Thr374", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 374, "start_aa": "Thr", "end_pos": 374, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr374", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q4AB27-1" }, { "uniprot_canonical_ac": "Q4ABD8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q4ABD8", "url": "https://www.uniprot.org/uniprotkb/Q4ABD8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 256, "chemical_mass": 26360.0, "gene_names": "His1:CG33807;CG33807;Dmel\\CG33807;Dmel_CG33807;His1:CG33807", "protein_name": "", "disease": [ { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q4ABD8", "url": "https://www.uniprot.org/uniprotkb/Q4ABD8" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q4ABD8", "url": "https://www.uniprot.org/uniprotkb/Q4ABD8" } ], "pmid": "" }, { "name": "nucleosome", "id": "GO:0000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000786", "evidence": [ { "database": "UniProtKB", "id": "Q4ABD8", "url": "https://www.uniprot.org/uniprotkb/Q4ABD8" } ], "pmid": "" } ], "molecular_function": [ { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "Q4ABD8", "url": "https://www.uniprot.org/uniprotkb/Q4ABD8" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "Q4ABD8", "url": "https://www.uniprot.org/uniprotkb/Q4ABD8" } ], "pmid": "" }, { "name": "nucleosomal DNA binding", "id": "GO:0031492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031492", "evidence": [ { "database": "UniProtKB", "id": "Q4ABD8", "url": "https://www.uniprot.org/uniprotkb/Q4ABD8" } ], "pmid": "" }, { "name": "structural constituent of chromatin", "id": "GO:0030527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030527", "evidence": [ { "database": "UniProtKB", "id": "Q4ABD8", "url": "https://www.uniprot.org/uniprotkb/Q4ABD8" } ], "pmid": "" } ], "biological_process": [ { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "Q4ABD8", "url": "https://www.uniprot.org/uniprotkb/Q4ABD8" } ], "pmid": "" }, { "name": "chromosome condensation", "id": "GO:0030261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030261", "evidence": [ { "database": "UniProtKB", "id": "Q4ABD8", "url": "https://www.uniprot.org/uniprotkb/Q4ABD8" } ], "pmid": "" }, { "name": "negative regulation of DNA recombination", "id": "GO:0045910", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045910", "evidence": [ { "database": "UniProtKB", "id": "Q4ABD8", "url": "https://www.uniprot.org/uniprotkb/Q4ABD8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q4ABD8-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Thr43", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 43, "start_aa": "Thr", "end_pos": 43, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr43", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q4ABD8-1" }, { "uniprot_canonical_ac": "Q4ABF1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q4ABF1", "url": "https://www.uniprot.org/uniprotkb/Q4ABF1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 180, "chemical_mass": 21164.0, "gene_names": "Dmel\\CG33928;CG33928;Dmel\\CG33928;Dmel_CG33928", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q4ABF1-1" }, { "uniprot_canonical_ac": "Q4ABF4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q4ABF4", "url": "https://www.uniprot.org/uniprotkb/Q4ABF4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 173, "chemical_mass": 20559.0, "gene_names": "Dmel\\CG33679;BP1003;CG33679;Dmel\\CG33679;Dmel_CG33679", "protein_name": "MD-2-related lipid-recognition domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q4ABF4-1" }, { "uniprot_canonical_ac": "Q4ABF8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q4ABF8", "url": "https://www.uniprot.org/uniprotkb/Q4ABF8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 178, "chemical_mass": 20748.0, "gene_names": "Dmel\\CG33643;CG33643;Dmel\\CG33643;Dmel_CG33643", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q4ABF8-1" }, { "uniprot_canonical_ac": "Q4ABG8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q4ABG8", "url": "https://www.uniprot.org/uniprotkb/Q4ABG8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 180, "chemical_mass": 21314.0, "gene_names": "Dmel\\CG33723;CG33723;Dmel\\CG33723;Dmel_CG33723", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q4ABG8-1" }, { "uniprot_canonical_ac": "Q4ABH5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q4ABH5", "url": "https://www.uniprot.org/uniprotkb/Q4ABH5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 178, "chemical_mass": 20608.0, "gene_names": "Dmel\\CG33771;CG14458;CG33771;Dmel\\CG33771;Dmel_CG33771", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q4ABH5-1" }, { "uniprot_canonical_ac": "Q4ABJ1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q4ABJ1", "url": "https://www.uniprot.org/uniprotkb/Q4ABJ1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 178, "chemical_mass": 21260.0, "gene_names": "Dmel\\CG33689;CG33689;Dmel\\CG33689;Dmel_CG33689", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q4ABJ1-1" }, { "uniprot_canonical_ac": "Q4ABJ4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q4ABJ4", "url": "https://www.uniprot.org/uniprotkb/Q4ABJ4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 178, "chemical_mass": 21341.0, "gene_names": "Dmel\\CG33795;CG33795;Dmel\\CG33795;Dmel_CG33795", "protein_name": "MD-2-related lipid-recognition domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q4ABJ4-1" }, { "uniprot_canonical_ac": "Q4ABK1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q4ABK1", "url": "https://www.uniprot.org/uniprotkb/Q4ABK1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 172, "chemical_mass": 20251.0, "gene_names": "Dmel\\CG33777;CG33777;Dmel\\CG33777;Dmel_CG33777", "protein_name": "MD-2-related lipid-recognition domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q4ABK1-1" }, { "uniprot_canonical_ac": "Q8IP19-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1081, "chemical_mass": 113665.0, "gene_names": "dac;BG:DS02780.3;CG4952;DAC;Dac2-3;Dachshund;Dach;Dac;Dm-DAC;Dmel\\CG4952;Dmel_CG4952;dach;dac;l(2)36Ae;l(2)rK364;spn", "protein_name": "", "disease": [], "biological_process": [ { "name": "compound eye development", "id": "GO:0048749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048749", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "leg disc proximal/distal pattern formation", "id": "GO:0007479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007479", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "genital disc morphogenesis", "id": "GO:0007483", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007483", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "mushroom body development", "id": "GO:0016319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016319", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "spermathecum morphogenesis", "id": "GO:0035211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035211", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "genital disc development", "id": "GO:0035215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035215", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "genital disc sexually dimorphic development", "id": "GO:0035263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035263", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "compound eye photoreceptor development", "id": "GO:0042051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042051", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "photoreceptor cell fate specification", "id": "GO:0043704", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043704", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "antennal joint development", "id": "GO:0048098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048098", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8IP19-1", "start_pos": "706", "end_pos": "706", "site_lbl": "Thr706", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 706, "start_aa": "Thr", "end_pos": 706, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr706", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q8IP19-1" }, { "uniprot_canonical_ac": "Q59E04-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q59E04", "url": "https://www.uniprot.org/uniprotkb/Q59E04" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 276, "chemical_mass": 29995.0, "gene_names": "7B2;7B2;CG1168;Dmel\\CG1168;FBgn0040073;d7B2", "protein_name": "Neuroendocrine protein 7B2", "disease": [ { "disease_id": "DOID:3946", "name": "pituitary-dependent Cushing's disease", "description": "", "url": "https://disease-ontology.org/term/DOID:3946", "evidence": [ { "id": "3946", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3946" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q59E04", "url": "https://www.uniprot.org/uniprotkb/Q59E04" } ], "pmid": "" }, { "name": "secretory granule", "id": "GO:0030141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030141", "evidence": [ { "database": "UniProtKB", "id": "Q59E04", "url": "https://www.uniprot.org/uniprotkb/Q59E04" } ], "pmid": "" } ], "biological_process": [ { "name": "neuropeptide signaling pathway", "id": "GO:0007218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007218", "evidence": [ { "database": "UniProtKB", "id": "Q59E04", "url": "https://www.uniprot.org/uniprotkb/Q59E04" } ], "pmid": "" }, { "name": "regulation of hormone secretion", "id": "GO:0046883", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046883", "evidence": [ { "database": "UniProtKB", "id": "Q59E04", "url": "https://www.uniprot.org/uniprotkb/Q59E04" } ], "pmid": "" }, { "name": "positive regulation of proteolysis", "id": "GO:0045862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045862", "evidence": [ { "database": "UniProtKB", "id": "Q59E04", "url": "https://www.uniprot.org/uniprotkb/Q59E04" } ], "pmid": "" } ], "molecular_function": [ { "name": "peptidase activator activity", "id": "GO:0016504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016504", "evidence": [ { "database": "UniProtKB", "id": "Q59E04", "url": "https://www.uniprot.org/uniprotkb/Q59E04" } ], "pmid": "" }, { "name": "enzyme regulator activity", "id": "GO:0030234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030234", "evidence": [ { "database": "UniProtKB", "id": "Q59E04", "url": "https://www.uniprot.org/uniprotkb/Q59E04" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q59E04-1" }, { "uniprot_canonical_ac": "Q59E05-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q59E05", "url": "https://www.uniprot.org/uniprotkb/Q59E05" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 337, "chemical_mass": 39178.0, "gene_names": "Dmel\\CG14667;CG14667;Dmel\\CG14667;Dmel_CG14667", "protein_name": "Transcription factor Ouib", "disease": [], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "Q59E05", "url": "https://www.uniprot.org/uniprotkb/Q59E05" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q59E05", "url": "https://www.uniprot.org/uniprotkb/Q59E05" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "Q59E05", "url": "https://www.uniprot.org/uniprotkb/Q59E05" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q59E05", "url": "https://www.uniprot.org/uniprotkb/Q59E05" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "Q59E05", "url": "https://www.uniprot.org/uniprotkb/Q59E05" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q59E05", "url": "https://www.uniprot.org/uniprotkb/Q59E05" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q59E05", "url": "https://www.uniprot.org/uniprotkb/Q59E05" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q59E05", "url": "https://www.uniprot.org/uniprotkb/Q59E05" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q59E05-1" }, { "uniprot_canonical_ac": "Q76NR6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q76NR6", "url": "https://www.uniprot.org/uniprotkb/Q76NR6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 319, "chemical_mass": 35360.0, "gene_names": "regucalcin;CG1803;Dmel\\CG1803;Dmel_CG1803;Regucalcin;RgN;T1;regucalcin", "protein_name": "Regucalcin", "disease": [ { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:1168", "name": "familial hyperlipidemia", "description": "A lipid metabolism disease that is characterized by elevated levels of lipids in the blood.", "url": "https://disease-ontology.org/term/DOID:1168", "evidence": [ { "id": "1168", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1168" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "biological_process": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "Q76NR6", "url": "https://www.uniprot.org/uniprotkb/Q76NR6" } ], "pmid": "" }, { "name": "L-ascorbic acid biosynthetic process", "id": "GO:0019853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019853", "evidence": [ { "database": "UniProtKB", "id": "Q76NR6", "url": "https://www.uniprot.org/uniprotkb/Q76NR6" } ], "pmid": "" } ], "molecular_function": [ { "name": "gluconolactonase activity", "id": "GO:0004341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004341", "evidence": [ { "database": "UniProtKB", "id": "Q76NR6", "url": "https://www.uniprot.org/uniprotkb/Q76NR6" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q76NR6", "url": "https://www.uniprot.org/uniprotkb/Q76NR6" } ], "pmid": "" }, { "name": "serine hydrolase activity", "id": "GO:0017171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017171", "evidence": [ { "database": "UniProtKB", "id": "Q76NR6", "url": "https://www.uniprot.org/uniprotkb/Q76NR6" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q76NR6", "url": "https://www.uniprot.org/uniprotkb/Q76NR6" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q76NR6", "url": "https://www.uniprot.org/uniprotkb/Q76NR6" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q76NR6", "url": "https://www.uniprot.org/uniprotkb/Q76NR6" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q76NR6", "url": "https://www.uniprot.org/uniprotkb/Q76NR6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q76NR6", "url": "https://www.uniprot.org/uniprotkb/Q76NR6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q76NR6-1" }, { "uniprot_canonical_ac": "Q7KS21-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KS21", "url": "https://www.uniprot.org/uniprotkb/Q7KS21" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 219, "chemical_mass": 24439.0, "gene_names": "Dmel\\CG33342;BP1089;CG33342;Dmel\\CG33342;Dmel_CG33342;mdcds_42691", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7KS21-1" }, { "uniprot_canonical_ac": "Q7KSA2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KSA2", "url": "https://www.uniprot.org/uniprotkb/Q7KSA2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 394, "chemical_mass": 44210.0, "gene_names": "Dmel\\CG31223;CG15694;CG31223;Dmel_CG31223", "protein_name": "HIT-type domain-containing protein", "disease": [], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q7KSA2", "url": "https://www.uniprot.org/uniprotkb/Q7KSA2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7KSA2-1", "start_pos": "191", "end_pos": "191", "site_lbl": "Thr191", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 191, "start_aa": "Thr", "end_pos": 191, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr191", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q7KSA2-1" }, { "uniprot_canonical_ac": "Q9VDS9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDS9", "url": "https://www.uniprot.org/uniprotkb/Q9VDS9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1363, "chemical_mass": 155497.0, "gene_names": "Ask1;ASK1;Ask1;Ask;CG4720;D-ASK;DASK1;DASK;DPk92B/ASK1;Dmel\\CG4720;Dmel_CG4720;MEKK5/ASK1;Pk92B;ask1;dASK1;dASK;dAsk1;pk92B", "protein_name": "", "disease": [ { "disease_id": "DOID:10976", "name": "membranous glomerulonephritis", "description": "", "url": "https://disease-ontology.org/term/DOID:10976", "evidence": [ { "id": "10976", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10976" } ], "weight": 0.0 }, { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:3526", "name": "cerebral infarction", "description": "A cerebrovascular disease that is characterized by an area of necrotic tissue in the brain resulting from a blockage or narrowing in the arteries supplying blood and oxygen to the brain.", "url": "https://disease-ontology.org/term/DOID:3526", "evidence": [ { "id": "3526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3526" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:670", "name": "amphetamine abuse", "description": "A substance abuse that involves the recurring use of amphetamines despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:670", "evidence": [ { "id": "670", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:670" } ], "weight": 0.0 }, { "disease_id": "DOID:8677", "name": "perinatal necrotizing enterocolitis", "description": "", "url": "https://disease-ontology.org/term/DOID:8677", "evidence": [ { "id": "8677", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8677" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VDS9", "url": "https://www.uniprot.org/uniprotkb/Q9VDS9" } ], "pmid": "" }, { "name": "MAP kinase kinase kinase activity", "id": "GO:0004709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004709", "evidence": [ { "database": "UniProtKB", "id": "Q9VDS9", "url": "https://www.uniprot.org/uniprotkb/Q9VDS9" } ], "pmid": "" }, { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "Q9VDS9", "url": "https://www.uniprot.org/uniprotkb/Q9VDS9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VDS9", "url": "https://www.uniprot.org/uniprotkb/Q9VDS9" } ], "pmid": "" } ], "biological_process": [ { "name": "MAPK cascade", "id": "GO:0000165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000165", "evidence": [ { "database": "UniProtKB", "id": "Q9VDS9", "url": "https://www.uniprot.org/uniprotkb/Q9VDS9" } ], "pmid": "" }, { "name": "positive regulation of JNK cascade", "id": "GO:0046330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046330", "evidence": [ { "database": "UniProtKB", "id": "Q9VDS9", "url": "https://www.uniprot.org/uniprotkb/Q9VDS9" } ], "pmid": "" }, { "name": "JNK cascade", "id": "GO:0007254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007254", "evidence": [ { "database": "UniProtKB", "id": "Q9VDS9", "url": "https://www.uniprot.org/uniprotkb/Q9VDS9" } ], "pmid": "" }, { "name": "p38MAPK cascade", "id": "GO:0038066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038066", "evidence": [ { "database": "UniProtKB", "id": "Q9VDS9", "url": "https://www.uniprot.org/uniprotkb/Q9VDS9" } ], "pmid": "" }, { "name": "regulation of adult chitin-containing cuticle pigmentation", "id": "GO:0048082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048082", "evidence": [ { "database": "UniProtKB", "id": "Q9VDS9", "url": "https://www.uniprot.org/uniprotkb/Q9VDS9" } ], "pmid": "" } ], "cellular_component": [ { "name": "protein kinase complex", "id": "GO:1902911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902911", "evidence": [ { "database": "UniProtKB", "id": "Q9VDS9", "url": "https://www.uniprot.org/uniprotkb/Q9VDS9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VDS9-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Ser107", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 107, "start_aa": "Ser", "end_pos": 107, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser107", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VDS9", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VDS9" } ] } ] }, { "uniprot_canonical_ac": "Q9VDS9-1", "start_pos": "1214", "end_pos": "1214", "site_lbl": "Thr1214", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1214, "start_aa": "Thr", "end_pos": 1214, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1214", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VDS9-1", "start_pos": "1344", "end_pos": "1344", "site_lbl": "Thr1344", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1344, "start_aa": "Thr", "end_pos": 1344, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1344", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VDS9-1" }, { "uniprot_canonical_ac": "Q9VEC4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VEC4", "url": "https://www.uniprot.org/uniprotkb/Q9VEC4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 450, "chemical_mass": 50716.0, "gene_names": "Dmel\\CG7208;CG 7208;CG7208;Dmel\\CG7208;Dmel_CG7208", "protein_name": "DUF4780 domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VEC4-1" }, { "uniprot_canonical_ac": "Q7KSK1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KSK1", "url": "https://www.uniprot.org/uniprotkb/Q7KSK1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 516, "chemical_mass": 56620.0, "gene_names": "Sp212;CG33329;Dmel\\CG33329;Dmel_CG33329;ORE-5;SP212;Sp212", "protein_name": "", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "Q7KSK1", "url": "https://www.uniprot.org/uniprotkb/Q7KSK1" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q7KSK1", "url": "https://www.uniprot.org/uniprotkb/Q7KSK1" } ], "pmid": "" }, { "name": "response to bacterium", "id": "GO:0009617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009617", "evidence": [ { "database": "UniProtKB", "id": "Q7KSK1", "url": "https://www.uniprot.org/uniprotkb/Q7KSK1" } ], "pmid": "" }, { "name": "response to fungus", "id": "GO:0009620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009620", "evidence": [ { "database": "UniProtKB", "id": "Q7KSK1", "url": "https://www.uniprot.org/uniprotkb/Q7KSK1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7KSK1-1", "start_pos": "199", "end_pos": "199", "site_lbl": "Thr199", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 199, "start_aa": "Thr", "end_pos": 199, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr199", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q7KSK1-1", "start_pos": "239", "end_pos": "239", "site_lbl": "Thr239", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 239, "start_aa": "Thr", "end_pos": 239, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr239", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q7KSK1-1", "start_pos": "250", "end_pos": "250", "site_lbl": "Thr250", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 250, "start_aa": "Thr", "end_pos": 250, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr250", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q7KSK1-1" }, { "uniprot_canonical_ac": "Q7KT14-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KT14", "url": "https://www.uniprot.org/uniprotkb/Q7KT14" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 197, "chemical_mass": 23032.0, "gene_names": "CheB38b;38E.23;CG33321;CG9329;CheB38b;Dmel\\CG33321;Dmel_CG33321", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q7KT14", "url": "https://www.uniprot.org/uniprotkb/Q7KT14" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q7KT14", "url": "https://www.uniprot.org/uniprotkb/Q7KT14" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "Q7KT14", "url": "https://www.uniprot.org/uniprotkb/Q7KT14" } ], "pmid": "" } ], "biological_process": [ { "name": "sensory perception of chemical stimulus", "id": "GO:0007606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007606", "evidence": [ { "database": "UniProtKB", "id": "Q7KT14", "url": "https://www.uniprot.org/uniprotkb/Q7KT14" } ], "pmid": "" }, { "name": "detection of pheromone", "id": "GO:0043695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043695", "evidence": [ { "database": "UniProtKB", "id": "Q7KT14", "url": "https://www.uniprot.org/uniprotkb/Q7KT14" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7KT14-1" }, { "uniprot_canonical_ac": "Q7KT22-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KT22", "url": "https://www.uniprot.org/uniprotkb/Q7KT22" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1292, "chemical_mass": 145261.0, "gene_names": "Dme_CG9270;CG9270;DmCG9270;Dme_CG9270;Dmel\\CG9270;Dmel_CG9270", "protein_name": "", "disease": [ { "disease_id": "DOID:13580", "name": "cholestasis", "description": "A bile duct disease that is characterized by where bile cannot flow from the liver to the duodenum.", "url": "https://disease-ontology.org/term/DOID:13580", "evidence": [ { "id": "13580", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13580" } ], "weight": 0.0 }, { "disease_id": "DOID:13619", "name": "extrahepatic cholestasis", "description": "A cholestasis resulting from causes located_in bile ducts outside the liver.", "url": "https://disease-ontology.org/term/DOID:13619", "evidence": [ { "id": "13619", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13619" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q7KT22", "url": "https://www.uniprot.org/uniprotkb/Q7KT22" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q7KT22", "url": "https://www.uniprot.org/uniprotkb/Q7KT22" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "Q7KT22", "url": "https://www.uniprot.org/uniprotkb/Q7KT22" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q7KT22", "url": "https://www.uniprot.org/uniprotkb/Q7KT22" } ], "pmid": "" } ], "biological_process": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "Q7KT22", "url": "https://www.uniprot.org/uniprotkb/Q7KT22" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7KT22-1" }, { "uniprot_canonical_ac": "Q7KT60-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KT60", "url": "https://www.uniprot.org/uniprotkb/Q7KT60" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2353, "chemical_mass": 268823.0, "gene_names": "anon-WO03042407.98;BG:DS02740.18;CG31817;DS02740.18;Dmel\\CG31817;Dmel_CG31817;anon-WO03042407.98;anon-WO03042407.99", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7KT60-1" }, { "uniprot_canonical_ac": "Q7KT77-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KT77", "url": "https://www.uniprot.org/uniprotkb/Q7KT77" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 876, "chemical_mass": 100981.0, "gene_names": "Dmel\\CG33310;BG:DS00929.6;CG15274;CG33310;Dmel\\CG33310;Dmel_CG33310;NaKbeta", "protein_name": "", "disease": [], "biological_process": [ { "name": "intracellular sodium ion homeostasis", "id": "GO:0006883", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006883", "evidence": [ { "database": "UniProtKB", "id": "Q7KT77", "url": "https://www.uniprot.org/uniprotkb/Q7KT77" } ], "pmid": "" }, { "name": "intracellular potassium ion homeostasis", "id": "GO:0030007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030007", "evidence": [ { "database": "UniProtKB", "id": "Q7KT77", "url": "https://www.uniprot.org/uniprotkb/Q7KT77" } ], "pmid": "" }, { "name": "sodium ion export across plasma membrane", "id": "GO:0036376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036376", "evidence": [ { "database": "UniProtKB", "id": "Q7KT77", "url": "https://www.uniprot.org/uniprotkb/Q7KT77" } ], "pmid": "" }, { "name": "potassium ion import across plasma membrane", "id": "GO:1990573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990573", "evidence": [ { "database": "UniProtKB", "id": "Q7KT77", "url": "https://www.uniprot.org/uniprotkb/Q7KT77" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATPase activator activity", "id": "GO:0001671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001671", "evidence": [ { "database": "UniProtKB", "id": "Q7KT77", "url": "https://www.uniprot.org/uniprotkb/Q7KT77" } ], "pmid": "" } ], "cellular_component": [ { "name": "sodium:potassium-exchanging ATPase complex", "id": "GO:0005890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005890", "evidence": [ { "database": "UniProtKB", "id": "Q7KT77", "url": "https://www.uniprot.org/uniprotkb/Q7KT77" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7KT77-1" }, { "uniprot_canonical_ac": "Q7KTG2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KTG2", "url": "https://www.uniprot.org/uniprotkb/Q7KTG2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 4333, "chemical_mass": 494320.0, "gene_names": "Apoltp;ApoLTPII;ApoLTPI;ApoLTP;Apoltp;CG15828;CT39214;Dmel\\CG15828;Dmel_CG15828;LTP;Ltp;apoLTP;apoltp;ltp", "protein_name": "", "disease": [ { "disease_id": "DOID:0111061", "name": "familial hypobetalipoproteinemia 2", "description": "A hypobetalipoproteinemia that has_material_basis_in homozygous or compound heterozygous mutation in the ANGPTL3 gene on chromosome 1p31.", "url": "https://disease-ontology.org/term/DOID:0111061", "evidence": [ { "id": "0111061", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111061" } ], "weight": 0.0 }, { "disease_id": "DOID:1184", "name": "nephrotic syndrome", "description": "A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.", "url": "https://disease-ontology.org/term/DOID:1184", "evidence": [ { "id": "1184", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1184" } ], "weight": 0.0 }, { "disease_id": "DOID:9452", "name": "steatotic liver disease", "description": "A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes.", "url": "https://disease-ontology.org/term/DOID:9452", "evidence": [ { "id": "9452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9452" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of lipid transport", "id": "GO:0032370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032370", "evidence": [ { "database": "UniProtKB", "id": "Q7KTG2", "url": "https://www.uniprot.org/uniprotkb/Q7KTG2" } ], "pmid": "" }, { "name": "sterol transport", "id": "GO:0015918", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015918", "evidence": [ { "database": "UniProtKB", "id": "Q7KTG2", "url": "https://www.uniprot.org/uniprotkb/Q7KTG2" } ], "pmid": "" }, { "name": "transport across blood-brain barrier", "id": "GO:0150104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150104", "evidence": [ { "database": "UniProtKB", "id": "Q7KTG2", "url": "https://www.uniprot.org/uniprotkb/Q7KTG2" } ], "pmid": "" }, { "name": "acylglycerol transport", "id": "GO:0034196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034196", "evidence": [ { "database": "UniProtKB", "id": "Q7KTG2", "url": "https://www.uniprot.org/uniprotkb/Q7KTG2" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipid transporter activity", "id": "GO:0005319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005319", "evidence": [ { "database": "UniProtKB", "id": "Q7KTG2", "url": "https://www.uniprot.org/uniprotkb/Q7KTG2" } ], "pmid": "" }, { "name": "lipoprotein particle receptor binding", "id": "GO:0070325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070325", "evidence": [ { "database": "UniProtKB", "id": "Q7KTG2", "url": "https://www.uniprot.org/uniprotkb/Q7KTG2" } ], "pmid": "" }, { "name": "nutrient reservoir activity", "id": "GO:0045735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045735", "evidence": [ { "database": "UniProtKB", "id": "Q7KTG2", "url": "https://www.uniprot.org/uniprotkb/Q7KTG2" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q7KTG2", "url": "https://www.uniprot.org/uniprotkb/Q7KTG2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q7KTG2", "url": "https://www.uniprot.org/uniprotkb/Q7KTG2" } ], "pmid": "" }, { "name": "basal part of cell", "id": "GO:0045178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045178", "evidence": [ { "database": "UniProtKB", "id": "Q7KTG2", "url": "https://www.uniprot.org/uniprotkb/Q7KTG2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7KTG2-1" }, { "uniprot_canonical_ac": "Q7KTH6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KTH6", "url": "https://www.uniprot.org/uniprotkb/Q7KTH6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 689, "chemical_mass": 79664.0, "gene_names": "CG13394;CG13394;CG42820;Dmel\\CG42820;Dmel_CG42820", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7KTH6-1" }, { "uniprot_canonical_ac": "Q7KTJ2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KTJ2", "url": "https://www.uniprot.org/uniprotkb/Q7KTJ2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 264, "chemical_mass": 29678.0, "gene_names": "Dmel\\CG8349;CG8349;Dmel\\CG8349;Dmel_CG8349", "protein_name": "cytidine deaminase", "disease": [ { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "cytidine deaminase activity", "id": "GO:0004126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004126", "evidence": [ { "database": "UniProtKB", "id": "Q7KTJ2", "url": "https://www.uniprot.org/uniprotkb/Q7KTJ2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q7KTJ2", "url": "https://www.uniprot.org/uniprotkb/Q7KTJ2" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q7KTJ2", "url": "https://www.uniprot.org/uniprotkb/Q7KTJ2" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q7KTJ2", "url": "https://www.uniprot.org/uniprotkb/Q7KTJ2" } ], "pmid": "" } ], "biological_process": [ { "name": "nucleobase-containing small molecule metabolic process", "id": "GO:0055086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055086", "evidence": [ { "database": "UniProtKB", "id": "Q7KTJ2", "url": "https://www.uniprot.org/uniprotkb/Q7KTJ2" } ], "pmid": "" }, { "name": "pyrimidine-containing compound metabolic process", "id": "GO:0072527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072527", "evidence": [ { "database": "UniProtKB", "id": "Q7KTJ2", "url": "https://www.uniprot.org/uniprotkb/Q7KTJ2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7KTJ2-1", "start_pos": "169", "end_pos": "169", "site_lbl": "Thr169", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 169, "start_aa": "Thr", "end_pos": 169, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr169", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q7KTJ2-1" }, { "uniprot_canonical_ac": "Q9VM74-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VM74", "url": "https://www.uniprot.org/uniprotkb/Q9VM74" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 715, "chemical_mass": 77438.0, "gene_names": "Nha1;CG10806;DmNHA1;Dmel\\CG10806;Dmel_CG10806;NHA1;Nha1;nha1", "protein_name": "", "disease": [], "molecular_function": [ { "name": "sodium:proton antiporter activity", "id": "GO:0015385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015385", "evidence": [ { "database": "UniProtKB", "id": "Q9VM74", "url": "https://www.uniprot.org/uniprotkb/Q9VM74" } ], "pmid": "" }, { "name": "chloride transmembrane transporter activity", "id": "GO:0015108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015108", "evidence": [ { "database": "UniProtKB", "id": "Q9VM74", "url": "https://www.uniprot.org/uniprotkb/Q9VM74" } ], "pmid": "" } ], "biological_process": [ { "name": "renal sodium ion transport", "id": "GO:0003096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003096", "evidence": [ { "database": "UniProtKB", "id": "Q9VM74", "url": "https://www.uniprot.org/uniprotkb/Q9VM74" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VM74", "url": "https://www.uniprot.org/uniprotkb/Q9VM74" } ], "pmid": "" }, { "name": "brush border", "id": "GO:0005903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005903", "evidence": [ { "database": "UniProtKB", "id": "Q9VM74", "url": "https://www.uniprot.org/uniprotkb/Q9VM74" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VM74-1", "start_pos": "39", "end_pos": "39", "site_lbl": "Thr39", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 39, "start_aa": "Thr", "end_pos": 39, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr39", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VM74-1" }, { "uniprot_canonical_ac": "Q7KUG3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KUG3", "url": "https://www.uniprot.org/uniprotkb/Q7KUG3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 88, "chemical_mass": 9680.0, "gene_names": "CG6100;CG14139;CG32084;CG33270;CG6100;Dmel\\CG33270;Dmel_CG33270;FBgn0053270", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7KUG3-1" }, { "uniprot_canonical_ac": "Q7KUI9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KUI9", "url": "https://www.uniprot.org/uniprotkb/Q7KUI9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 208, "chemical_mass": 24044.0, "gene_names": "Dmel\\CG33262;CG33262;Dmel\\CG33262;Dmel_CG33262", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7KUI9-1" }, { "uniprot_canonical_ac": "Q7KUV8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KUV8", "url": "https://www.uniprot.org/uniprotkb/Q7KUV8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 305, "chemical_mass": 34985.0, "gene_names": "Dmel\\CG6023;CG6023;Dmel\\CG6023;Dmel_CG6023", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7KUV8-1" }, { "uniprot_canonical_ac": "Q7KV35-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KV35", "url": "https://www.uniprot.org/uniprotkb/Q7KV35" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1584, "chemical_mass": 174342.0, "gene_names": "Dmel\\CG33235;CG15192;CG33235;Dmel\\CG33235;Dmel_CG33235", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7KV35-1", "start_pos": "1383", "end_pos": "1383", "site_lbl": "Thr1383", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1383, "start_aa": "Thr", "end_pos": 1383, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1383", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q7KV35-1", "start_pos": "163", "end_pos": "163", "site_lbl": "Thr163", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 163, "start_aa": "Thr", "end_pos": 163, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr163", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q7KV35", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7KV35" } ] } ] } ], "record_id": "Q7KV35-1" }, { "uniprot_canonical_ac": "Q7KVP9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 769, "chemical_mass": 88011.0, "gene_names": "Xpd;CG9433;DhR3;DhXPD;DmXPD;Dmel\\CG9433;Dmel_CG9433;ERCC2;XPD/ERCC2;XPD;Xpd;l(2)SH2 2137;l(2)SH2137;xpd", "protein_name": "General transcription and DNA repair factor IIH helicase subunit XPD", "disease": [ { "disease_id": "DOID:0050427", "name": "xeroderma pigmentosum", "description": "A syndrome that is characterized by a deficiency in the ability to repair ultraviolet damage that has_material_basis_in autosomal recessive inheritance of DNA repair.", "url": "https://disease-ontology.org/term/DOID:0050427", "evidence": [ { "id": "0050427", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050427" } ], "weight": 0.0 }, { "disease_id": "DOID:0050908", "name": "myelodysplastic syndrome", "description": "A bone marrow cancer that is characterized by under production of white blood cells, red blood cells and platelets.", "url": "https://disease-ontology.org/term/DOID:0050908", "evidence": [ { "id": "0050908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050908" } ], "weight": 0.0 }, { "disease_id": "DOID:0060655", "name": "autosomal recessive congenital ichthyosis", "description": "An ichthyosis that is characterized by autosomal recessive inheritance and abnormal skin scaling over the whole body due to a defect in keratinization.", "url": "https://disease-ontology.org/term/DOID:0060655", "evidence": [ { "id": "0060655", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060655" } ], "weight": 0.0 }, { "disease_id": "DOID:0080912", "name": "cerebrooculofacioskeletal syndrome 2", "description": "A cerebrooculofacioskeletal syndrome that has_material_basis_in compound heterozygous mutation in the DNA repair gene XPD (ERCC2) on chromosome 19q13.", "url": "https://disease-ontology.org/term/DOID:0080912", "evidence": [ { "id": "0080912", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080912" } ], "weight": 0.0 }, { "disease_id": "DOID:0110845", "name": "xeroderma pigmentosum group D", "description": "A xeroderma pigmentosum that has_material_basis_in homozygous or compound heterozygous mutation in the excision repair gene ERCC2 on chromosome 19q13.", "url": "https://disease-ontology.org/term/DOID:0110845", "evidence": [ { "id": "0110845", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110845" } ], "weight": 0.0 }, { "disease_id": "DOID:0111873", "name": "photosensitive trichothiodystrophy 1", "description": "A photosensitive trichothiodystrophy that has_material_basis_in homozygous or compound heterozygous mutation in the ERCC2 gene on chromosome 19q13.32.", "url": "https://disease-ontology.org/term/DOID:0111873", "evidence": [ { "id": "0111873", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111873" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:11088", "name": "asphyxia neonatorum", "description": "A respiratory system disease that is characterized by deprivation of oxygen to a newborn infant that lasts long enough during the birth process to cause physical harm, usually to the brain.", "url": "https://disease-ontology.org/term/DOID:11088", "evidence": [ { "id": "11088", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11088" } ], "weight": 0.0 }, { "disease_id": "DOID:12689", "name": "acoustic neuroma", "description": "", "url": "https://disease-ontology.org/term/DOID:12689", "evidence": [ { "id": "12689", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12689" } ], "weight": 0.0 }, { "disease_id": "DOID:14250", "name": "Down syndrome", "description": "A chromosomal duplication syndrome that is characterized by flat-looking facial features and weak muscle tone (hypotonia) in infancy and is caused by trisomy of all or a critical portion of chromosome 21 and is associated with intellectual disability.", "url": "https://disease-ontology.org/term/DOID:14250", "evidence": [ { "id": "14250", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14250" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:1909", "name": "melanoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from melanocytes which are found in skin, the bowel and the eye.", "url": "https://disease-ontology.org/term/DOID:1909", "evidence": [ { "id": "1909", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1909" } ], "weight": 0.0 }, { "disease_id": "DOID:2152", "name": "ovary epithelial cancer", "description": "An ovarian cancer that is derives_from ovarian surface epithelium.", "url": "https://disease-ontology.org/term/DOID:2152", "evidence": [ { "id": "2152", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2152" } ], "weight": 0.0 }, { "disease_id": "DOID:2960", "name": "photosensitive trichothiodystrophy", "description": "A trichothiodystrophy characterized by skin that is extremely sensitive to ultraviolet (UV) rays from sunlight.", "url": "https://disease-ontology.org/term/DOID:2960", "evidence": [ { "id": "2960", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2960" } ], "weight": 0.0 }, { "disease_id": "DOID:2962", "name": "Cockayne syndrome", "description": "A syndrome that is characterized by an abnormally small head size (microcephaly), a failure to gain weight and grow at the expected rate (failure to thrive) leading to very short stature, and delayed development.", "url": "https://disease-ontology.org/term/DOID:2962", "evidence": [ { "id": "2962", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2962" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:37", "name": "skin disease", "description": "An integumentary system disease that is located_in skin.", "url": "https://disease-ontology.org/term/DOID:37", "evidence": [ { "id": "37", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:37" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:4448", "name": "macular degeneration", "description": "A retinal degeneration characterized by gradual deterioration of light-sensing cells in the tissues at the back of the eye and has_symptom vision loss.", "url": "https://disease-ontology.org/term/DOID:4448", "evidence": [ { "id": "4448", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4448" } ], "weight": 0.0 }, { "disease_id": "DOID:635", "name": "acquired immunodeficiency syndrome", "description": "A Human immunodeficiency virus infectious disease that results_in reduction in the numbers of CD4-bearing helper T cells below 200 per microliter of blood or 14% of all lymphocytes thereby rendering the subject highly vulnerable to life-threatening infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted_by sexual contact, transmitted_by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted_by congenital method, and transmitted_by contaminated needles. Opportunistic infections are common in people with AIDS.", "url": "https://disease-ontology.org/term/DOID:635", "evidence": [ { "id": "635", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:635" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:8552", "name": "chronic myeloid leukemia", "description": "A myeloid leukemia that is characterized by over production of white blood cells.", "url": "https://disease-ontology.org/term/DOID:8552", "evidence": [ { "id": "8552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8552" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9538", "name": "multiple myeloma", "description": "A myeloid neoplasm that is located_in the plasma cells in bone marrow.", "url": "https://disease-ontology.org/term/DOID:9538", "evidence": [ { "id": "9538", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9538" } ], "weight": 0.0 }, { "disease_id": "DOID:9655", "name": "oral mucosa leukoplakia", "description": "A mouth disease that is characterized by a white patch or plaque that develops in the oral cavity and is strongly associated with smoking.", "url": "https://disease-ontology.org/term/DOID:9655", "evidence": [ { "id": "9655", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9655" } ], "weight": 0.0 }, { "disease_id": "DOID:9669", "name": "senile cataract", "description": "A cataract that is characterized by thickening and loss of transparency of the lens with age progression, caused by a multifactorial etiology related to aging.", "url": "https://disease-ontology.org/term/DOID:9669", "evidence": [ { "id": "9669", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9669" } ], "weight": 0.0 }, { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "DNA helicase activity", "id": "GO:0003678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003678", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "5'-3' DNA helicase activity", "id": "GO:0043139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043139", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "transcription factor TFIIH holo complex", "id": "GO:0005675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005675", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "transcription factor TFIIH core complex", "id": "GO:0000439", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000439", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "polytene chromosome", "id": "GO:0005700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005700", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "polytene chromosome puff", "id": "GO:0005703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005703", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "polytene chromosome interband", "id": "GO:0005705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005705", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "response to UV", "id": "GO:0009411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009411", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "transcription by RNA polymerase II", "id": "GO:0006366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006366", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase II promoter", "id": "GO:0006367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006367", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "regulation of mitotic nuclear division", "id": "GO:0007088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007088", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "nucleotide-excision repair", "id": "GO:0006289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006289", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "negative regulation of G2/M transition of mitotic cell cycle", "id": "GO:0010972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010972", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "RNA polymerase II promoter clearance", "id": "GO:0001111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001111", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "transcription open complex formation at RNA polymerase II promoter", "id": "GO:0001113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001113", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "regulation of chromosome segregation", "id": "GO:0051983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051983", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "hair cell differentiation", "id": "GO:0035315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035315", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "positive regulation of mitotic recombination", "id": "GO:0045951", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045951", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "regulation of syncytial blastoderm mitotic cell cycle", "id": "GO:0007348", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007348", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7KVP9-1" }, { "uniprot_canonical_ac": "Q7PLB8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7PLB8", "url": "https://www.uniprot.org/uniprotkb/Q7PLB8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2394, "chemical_mass": 266851.0, "gene_names": "FASN3;80Ff;CG17374;DM_7289423;Dmel\\CG17374;Dmel_CG17374;FASN3;FASN[CG17374];FAS[CG17374];FAS;fasn3;l(3)80Ff;l(3)Lh4B;l4B", "protein_name": "Fatty acid synthase", "disease": [ { "disease_id": "DOID:0080000", "name": "muscular disease", "description": "A musculoskeletal system disease that affects the muscles.", "url": "https://disease-ontology.org/term/DOID:0080000", "evidence": [ { "id": "0080000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080000" } ], "weight": 0.0 }, { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "biological_process": [ { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "Q7PLB8", "url": "https://www.uniprot.org/uniprotkb/Q7PLB8" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphopantetheine binding", "id": "GO:0031177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031177", "evidence": [ { "database": "UniProtKB", "id": "Q7PLB8", "url": "https://www.uniprot.org/uniprotkb/Q7PLB8" } ], "pmid": "" }, { "name": "fatty acid synthase activity", "id": "GO:0004312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004312", "evidence": [ { "database": "UniProtKB", "id": "Q7PLB8", "url": "https://www.uniprot.org/uniprotkb/Q7PLB8" } ], "pmid": "" }, { "name": "[acyl-carrier-protein] S-acetyltransferase activity", "id": "GO:0004313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004313", "evidence": [ { "database": "UniProtKB", "id": "Q7PLB8", "url": "https://www.uniprot.org/uniprotkb/Q7PLB8" } ], "pmid": "" }, { "name": "3-oxoacyl-[acyl-carrier-protein] synthase activity", "id": "GO:0004315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004315", "evidence": [ { "database": "UniProtKB", "id": "Q7PLB8", "url": "https://www.uniprot.org/uniprotkb/Q7PLB8" } ], "pmid": "" }, { "name": "3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity", "id": "GO:0004316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004316", "evidence": [ { "database": "UniProtKB", "id": "Q7PLB8", "url": "https://www.uniprot.org/uniprotkb/Q7PLB8" } ], "pmid": "" }, { "name": "fatty acyl-[ACP] hydrolase activity", "id": "GO:0016297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016297", "evidence": [ { "database": "UniProtKB", "id": "Q7PLB8", "url": "https://www.uniprot.org/uniprotkb/Q7PLB8" } ], "pmid": "" }, { "name": "(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity", "id": "GO:0019171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019171", "evidence": [ { "database": "UniProtKB", "id": "Q7PLB8", "url": "https://www.uniprot.org/uniprotkb/Q7PLB8" } ], "pmid": "" }, { "name": "enoyl-[acyl-carrier-protein] reductase (NADPH) activity", "id": "GO:0141148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141148", "evidence": [ { "database": "UniProtKB", "id": "Q7PLB8", "url": "https://www.uniprot.org/uniprotkb/Q7PLB8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7PLB8-1" }, { "uniprot_canonical_ac": "Q7PLI0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7PLI0", "url": "https://www.uniprot.org/uniprotkb/Q7PLI0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 781, "chemical_mass": 86823.0, "gene_names": "p120ctn;CG17484;Dmel\\CG17484;Dmel_CG17484;Dp120[ctn];Dp120ctn;P120-catenin;P120ctn;P120;dP120ctn;dp120ctn;p120[ctn];p120ctn;p120", "protein_name": "", "disease": [ { "disease_id": "DOID:0050431", "name": "arrhythmogenic right ventricular cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by hypokinetic areas involving the free wall of the right ventricle, with fibrofatty replacement of the right ventricular myocardium, with associated arrhythmias originating in the right ventricle and limited or no involvement of the left ventricle.", "url": "https://disease-ontology.org/term/DOID:0050431", "evidence": [ { "id": "0050431", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050431" } ], "weight": 0.0 }, { "disease_id": "DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050866", "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ], "weight": 0.0 }, { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0080346", "name": "blepharocheilodontic syndrome 2", "description": "A blepharocheilodontic syndrome that has_material_basis_in heterozygous mutation in the CTNND1 gene on chromosome 11q12.", "url": "https://disease-ontology.org/term/DOID:0080346", "evidence": [ { "id": "0080346", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080346" } ], "weight": 0.0 }, { "disease_id": "DOID:0110077", "name": "arrhythmogenic right ventricular dysplasia 9", "description": "An arrhythmogenic right ventricular dysplasia that has_material_basis_in heterozygous mutations in the PKP2 gene on chromosome 12p11.", "url": "https://disease-ontology.org/term/DOID:0110077", "evidence": [ { "id": "0110077", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110077" } ], "weight": 0.0 }, { "disease_id": "DOID:11198", "name": "DiGeorge syndrome", "description": "A syndrome that has_material_basis_in a large deletion of the chromosome 22q11.2 region which includes the DGS gene needed for development of the thymus and related glands with subsequent lack of T-cell production.", "url": "https://disease-ontology.org/term/DOID:11198", "evidence": [ { "id": "11198", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11198" } ], "weight": 0.0 }, { "disease_id": "DOID:1470", "name": "major depressive disorder", "description": "A depressive disorder that is characterized by at least two weeks of loss of interest or pleasure in normally enjoyable activities or depressed mood along with additional cognitive or somatic impairments such as appetite or weight changes, sleep difficulties, psychomotor agitation or retardation, fatigue or loss of energy, diminished ability to think or concentrate, feelings of worthlessness or excessive guilt, and suicidality.", "url": "https://disease-ontology.org/term/DOID:1470", "evidence": [ { "id": "1470", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1470" } ], "weight": 0.0 }, { "disease_id": "DOID:2030", "name": "anxiety disorder", "description": "A cognitive disorder that involves an excessive, irrational dread of everyday situations.", "url": "https://disease-ontology.org/term/DOID:2030", "evidence": [ { "id": "2030", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2030" } ], "weight": 0.0 }, { "disease_id": "DOID:2121", "name": "ectodermal dysplasia", "description": "A syndrome characterized by abnormal development in 2 or more ectodermal structures (hair, nails, teeth, and sweat glands) without other systemic findings.", "url": "https://disease-ontology.org/term/DOID:2121", "evidence": [ { "id": "2121", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2121" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q7PLI0", "url": "https://www.uniprot.org/uniprotkb/Q7PLI0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q7PLI0", "url": "https://www.uniprot.org/uniprotkb/Q7PLI0" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "Q7PLI0", "url": "https://www.uniprot.org/uniprotkb/Q7PLI0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q7PLI0", "url": "https://www.uniprot.org/uniprotkb/Q7PLI0" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "Q7PLI0", "url": "https://www.uniprot.org/uniprotkb/Q7PLI0" } ], "pmid": "" } ], "biological_process": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "Q7PLI0", "url": "https://www.uniprot.org/uniprotkb/Q7PLI0" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "Q7PLI0", "url": "https://www.uniprot.org/uniprotkb/Q7PLI0" } ], "pmid": "" }, { "name": "dendritic spine morphogenesis", "id": "GO:0060997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060997", "evidence": [ { "database": "UniProtKB", "id": "Q7PLI0", "url": "https://www.uniprot.org/uniprotkb/Q7PLI0" } ], "pmid": "" }, { "name": "adherens junction maintenance", "id": "GO:0034334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034334", "evidence": [ { "database": "UniProtKB", "id": "Q7PLI0", "url": "https://www.uniprot.org/uniprotkb/Q7PLI0" } ], "pmid": "" }, { "name": "compound eye morphogenesis", "id": "GO:0001745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001745", "evidence": [ { "database": "UniProtKB", "id": "Q7PLI0", "url": "https://www.uniprot.org/uniprotkb/Q7PLI0" } ], "pmid": "" } ], "molecular_function": [ { "name": "cadherin binding", "id": "GO:0045296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045296", "evidence": [ { "database": "UniProtKB", "id": "Q7PLI0", "url": "https://www.uniprot.org/uniprotkb/Q7PLI0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7PLI0-1" }, { "uniprot_canonical_ac": "Q86BI5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q86BI5", "url": "https://www.uniprot.org/uniprotkb/Q86BI5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 121, "chemical_mass": 13838.0, "gene_names": "CG13057;CG13057;CG33060;Dmel\\CG33060;Dmel_CG33060", "protein_name": "Protein dpy-30 homolog", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q86BI5-1" }, { "uniprot_canonical_ac": "Q8IML0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IML0", "url": "https://www.uniprot.org/uniprotkb/Q8IML0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 373, "chemical_mass": 42066.0, "gene_names": "Dmel\\CG14507;CG14507;Dmel\\CG14507;Dmel_CG14507", "protein_name": "Phospholipase A2", "disease": [ { "disease_id": "DOID:0111677", "name": "familial benign fleck retina", "description": "A retinal disease characterized by a striking pattern of diffuse, yellow-white, fleck-like lesions extending to the far periphery of the retina but with no apparent visual or electrophysiologic deficits that has_material_basis_in homozygous or compound heterozygous mutation in the PLA2G5 gene on chromosome 1p36.13.", "url": "https://disease-ontology.org/term/DOID:0111677", "evidence": [ { "id": "0111677", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111677" } ], "weight": 0.0 }, { "disease_id": "DOID:11151", "name": "cholecystolithiasis", "description": "", "url": "https://disease-ontology.org/term/DOID:11151", "evidence": [ { "id": "11151", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11151" } ], "weight": 0.0 }, { "disease_id": "DOID:11204", "name": "allergic conjunctivitis", "description": "A chronic conjunctivitis that is an inflammation of the conjunctiva involing red, itchy, and watery eyes a resulting from an exposure to an allergen or an irritant.", "url": "https://disease-ontology.org/term/DOID:11204", "evidence": [ { "id": "11204", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11204" } ], "weight": 0.0 }, { "disease_id": "DOID:11394", "name": "adult respiratory distress syndrome", "description": "A respiratory failure that results from diffuse injury to the endothelium of the lung (as in sepsis, chest trauma, massive blood transfusion, aspiration of the gastric contents, or pneumonia) and is characterized by pulmonary edema with an abnormally high amount of protein in the edematous fluid and by difficult rapid breathing and hypoxemia.", "url": "https://disease-ontology.org/term/DOID:11394", "evidence": [ { "id": "11394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11394" } ], "weight": 0.0 }, { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 }, { "disease_id": "DOID:526", "name": "human immunodeficiency virus infectious disease", "description": "A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.", "url": "https://disease-ontology.org/term/DOID:526", "evidence": [ { "id": "526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:526" } ], "weight": 0.0 }, { "disease_id": "DOID:8534", "name": "gastroesophageal reflux disease", "description": "", "url": "https://disease-ontology.org/term/DOID:8534", "evidence": [ { "id": "8534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8534" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q8IML0", "url": "https://www.uniprot.org/uniprotkb/Q8IML0" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "Q8IML0", "url": "https://www.uniprot.org/uniprotkb/Q8IML0" } ], "pmid": "" }, { "name": "arachidonate secretion", "id": "GO:0050482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050482", "evidence": [ { "database": "UniProtKB", "id": "Q8IML0", "url": "https://www.uniprot.org/uniprotkb/Q8IML0" } ], "pmid": "" }, { "name": "phospholipid metabolic process", "id": "GO:0006644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006644", "evidence": [ { "database": "UniProtKB", "id": "Q8IML0", "url": "https://www.uniprot.org/uniprotkb/Q8IML0" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q8IML0", "url": "https://www.uniprot.org/uniprotkb/Q8IML0" } ], "pmid": "" }, { "name": "phospholipase A2 activity", "id": "GO:0004623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004623", "evidence": [ { "database": "UniProtKB", "id": "Q8IML0", "url": "https://www.uniprot.org/uniprotkb/Q8IML0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IML0-1" }, { "uniprot_canonical_ac": "Q8IMQ3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IMQ3", "url": "https://www.uniprot.org/uniprotkb/Q8IMQ3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 988, "chemical_mass": 110326.0, "gene_names": "Dmel\\CG31077;CG31077;Dmel\\CG31077;Dmel_CG31077", "protein_name": "Chitin-binding type-2 domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q8IMQ3", "url": "https://www.uniprot.org/uniprotkb/Q8IMQ3" } ], "pmid": "" }, { "name": "external encapsulating structure", "id": "GO:0030312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030312", "evidence": [ { "database": "UniProtKB", "id": "Q8IMQ3", "url": "https://www.uniprot.org/uniprotkb/Q8IMQ3" } ], "pmid": "" } ], "molecular_function": [ { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "Q8IMQ3", "url": "https://www.uniprot.org/uniprotkb/Q8IMQ3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IMQ3-1" }, { "uniprot_canonical_ac": "Q8IMR4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IMR4", "url": "https://www.uniprot.org/uniprotkb/Q8IMR4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 402, "chemical_mass": 44796.0, "gene_names": "Yif1;CG5484;COP;Dmel\\CG5484;Dmel_CG5484;Yif1;anon-WO0118547.366;doc", "protein_name": "", "disease": [ { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q8IMR4", "url": "https://www.uniprot.org/uniprotkb/Q8IMR4" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q8IMR4", "url": "https://www.uniprot.org/uniprotkb/Q8IMR4" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment", "id": "GO:0005793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005793", "evidence": [ { "database": "UniProtKB", "id": "Q8IMR4", "url": "https://www.uniprot.org/uniprotkb/Q8IMR4" } ], "pmid": "" }, { "name": "COPII-coated ER to Golgi transport vesicle", "id": "GO:0030134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030134", "evidence": [ { "database": "UniProtKB", "id": "Q8IMR4", "url": "https://www.uniprot.org/uniprotkb/Q8IMR4" } ], "pmid": "" }, { "name": "endoplasmic reticulum exit site", "id": "GO:0070971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070971", "evidence": [ { "database": "UniProtKB", "id": "Q8IMR4", "url": "https://www.uniprot.org/uniprotkb/Q8IMR4" } ], "pmid": "" }, { "name": "cis-Golgi network", "id": "GO:0005801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005801", "evidence": [ { "database": "UniProtKB", "id": "Q8IMR4", "url": "https://www.uniprot.org/uniprotkb/Q8IMR4" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q8IMR4", "url": "https://www.uniprot.org/uniprotkb/Q8IMR4" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "Q8IMR4", "url": "https://www.uniprot.org/uniprotkb/Q8IMR4" } ], "pmid": "" }, { "name": "positive regulation of synapse pruning", "id": "GO:1905808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905808", "evidence": [ { "database": "UniProtKB", "id": "Q8IMR4", "url": "https://www.uniprot.org/uniprotkb/Q8IMR4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IMR4-1" }, { "uniprot_canonical_ac": "Q8IMT4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IMT4", "url": "https://www.uniprot.org/uniprotkb/Q8IMT4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 428, "chemical_mass": 49978.0, "gene_names": "CG13665;CG13665;CG31288;Dmel\\CG31288;Dmel_CG31288;Dro11-0", "protein_name": "CHK kinase-like domain-containing protein", "disease": [], "molecular_function": [ { "name": "ecdysteroid 22-kinase activity", "id": "GO:0106389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106389", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT4", "url": "https://www.uniprot.org/uniprotkb/Q8IMT4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IMT4-1" }, { "uniprot_canonical_ac": "Q8IN22-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IN22", "url": "https://www.uniprot.org/uniprotkb/Q8IN22" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 381, "chemical_mass": 44955.0, "gene_names": "Gr93d;93F.4;CG31335;DmGr93d;Dmel\\CG31335;Dmel_CG31335;GR93F.4;GR93d;Gr93F4;Gr93d", "protein_name": "Gustatory receptor", "disease": [], "biological_process": [ { "name": "male courtship behavior", "id": "GO:0008049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008049", "evidence": [ { "database": "UniProtKB", "id": "Q8IN22", "url": "https://www.uniprot.org/uniprotkb/Q8IN22" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q8IN22", "url": "https://www.uniprot.org/uniprotkb/Q8IN22" } ], "pmid": "" }, { "name": "monoatomic ion transmembrane transport", "id": "GO:0034220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034220", "evidence": [ { "database": "UniProtKB", "id": "Q8IN22", "url": "https://www.uniprot.org/uniprotkb/Q8IN22" } ], "pmid": "" }, { "name": "chemosensory behavior", "id": "GO:0007635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007635", "evidence": [ { "database": "UniProtKB", "id": "Q8IN22", "url": "https://www.uniprot.org/uniprotkb/Q8IN22" } ], "pmid": "" }, { "name": "sensory perception of taste", "id": "GO:0050909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050909", "evidence": [ { "database": "UniProtKB", "id": "Q8IN22", "url": "https://www.uniprot.org/uniprotkb/Q8IN22" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q8IN22", "url": "https://www.uniprot.org/uniprotkb/Q8IN22" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "Q8IN22", "url": "https://www.uniprot.org/uniprotkb/Q8IN22" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q8IN22", "url": "https://www.uniprot.org/uniprotkb/Q8IN22" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "Q8IN22", "url": "https://www.uniprot.org/uniprotkb/Q8IN22" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "Q8IN22", "url": "https://www.uniprot.org/uniprotkb/Q8IN22" } ], "pmid": "" }, { "name": "taste receptor activity", "id": "GO:0008527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008527", "evidence": [ { "database": "UniProtKB", "id": "Q8IN22", "url": "https://www.uniprot.org/uniprotkb/Q8IN22" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IN22-1" }, { "uniprot_canonical_ac": "Q8ING0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8ING0", "url": "https://www.uniprot.org/uniprotkb/Q8ING0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 520, "chemical_mass": 57228.0, "gene_names": "CG9645;CG31326;CG9645;Dmel\\CG31326;Dmel_CG31326;SPH144;cg9645", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q8ING0", "url": "https://www.uniprot.org/uniprotkb/Q8ING0" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q8ING0", "url": "https://www.uniprot.org/uniprotkb/Q8ING0" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q8ING0", "url": "https://www.uniprot.org/uniprotkb/Q8ING0" } ], "pmid": "" } ], "molecular_function": [ { "name": "serine-type peptidase activity", "id": "GO:0008236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008236", "evidence": [ { "database": "UniProtKB", "id": "Q8ING0", "url": "https://www.uniprot.org/uniprotkb/Q8ING0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8ING0-1" }, { "uniprot_canonical_ac": "Q8ING1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8ING1", "url": "https://www.uniprot.org/uniprotkb/Q8ING1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 861, "chemical_mass": 98033.0, "gene_names": "Dmel\\CG31327;BcDNA:AT17065;CG31327;Dmel\\CG31327;Dmel_CG31327", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8ING1-1", "start_pos": "291", "end_pos": "291", "site_lbl": "Thr291", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 291, "start_aa": "Thr", "end_pos": 291, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr291", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q8ING1-1" }, { "uniprot_canonical_ac": "Q8INY9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8INY9", "url": "https://www.uniprot.org/uniprotkb/Q8INY9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 212, "chemical_mass": 24534.0, "gene_names": "Dmel\\CG31804;CG31804;Dmel\\CG31804;Dmel_CG31804;NEST:bs12c10;NEST:bs13h04;NEST:bs27h11;NEST:bs34f07", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8INY9-1" }, { "uniprot_canonical_ac": "Q8IP11-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IP11", "url": "https://www.uniprot.org/uniprotkb/Q8IP11" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 233, "chemical_mass": 26411.0, "gene_names": "Tsen2;CG31812;Dmel\\CG31812;Dmel_CG31812;TSEN2;Tsen2", "protein_name": "tRNA-intron lyase", "disease": [ { "disease_id": "DOID:0060268", "name": "pontocerebellar hypoplasia type 2B", "description": "A severe pontocerebellar hypoplasia that is characterized by progressive microcephaly, clonus, dysphagia and failure to thrive, has_material_basis_in autosomal recessive inheritance of mutation in the TSEN2 gene.", "url": "https://disease-ontology.org/term/DOID:0060268", "evidence": [ { "id": "0060268", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060268" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q8IP11", "url": "https://www.uniprot.org/uniprotkb/Q8IP11" } ], "pmid": "" }, { "name": "tRNA-intron endonuclease complex", "id": "GO:0000214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000214", "evidence": [ { "database": "UniProtKB", "id": "Q8IP11", "url": "https://www.uniprot.org/uniprotkb/Q8IP11" } ], "pmid": "" } ], "biological_process": [ { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "Q8IP11", "url": "https://www.uniprot.org/uniprotkb/Q8IP11" } ], "pmid": "" }, { "name": "tRNA-type intron splice site recognition and cleavage", "id": "GO:0000379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000379", "evidence": [ { "database": "UniProtKB", "id": "Q8IP11", "url": "https://www.uniprot.org/uniprotkb/Q8IP11" } ], "pmid": "" } ], "molecular_function": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "Q8IP11", "url": "https://www.uniprot.org/uniprotkb/Q8IP11" } ], "pmid": "" }, { "name": "tRNA-intron lyase activity", "id": "GO:0000213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000213", "evidence": [ { "database": "UniProtKB", "id": "Q8IP11", "url": "https://www.uniprot.org/uniprotkb/Q8IP11" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IP11-1" }, { "uniprot_canonical_ac": "Q8IPE5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IPE5", "url": "https://www.uniprot.org/uniprotkb/Q8IPE5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 121, "chemical_mass": 14042.0, "gene_names": "pal;CG31882;Dmel\\CG31882;Dmel_CG31882;NEST:bs35a07;bs35a07.y1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q8IPE5", "url": "https://www.uniprot.org/uniprotkb/Q8IPE5" } ], "pmid": "" } ], "biological_process": [ { "name": "sperm DNA condensation", "id": "GO:0035092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035092", "evidence": [ { "database": "UniProtKB", "id": "Q8IPE5", "url": "https://www.uniprot.org/uniprotkb/Q8IPE5" } ], "pmid": "" } ], "molecular_function": [ { "name": "H3-H4 histone complex chaperone activity", "id": "GO:0000510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000510", "evidence": [ { "database": "UniProtKB", "id": "Q8IPE5", "url": "https://www.uniprot.org/uniprotkb/Q8IPE5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IPE5-1" }, { "uniprot_canonical_ac": "Q8IPF1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IPF1", "url": "https://www.uniprot.org/uniprotkb/Q8IPF1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 123, "chemical_mass": 14949.0, "gene_names": "anon-AE003623.1;CG31609;Dmel\\CG31609;Dmel_CG31609;anon-AE003623.1", "protein_name": "BPTI/Kunitz inhibitor domain-containing protein", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "Q8IPF1", "url": "https://www.uniprot.org/uniprotkb/Q8IPF1" } ], "pmid": "" }, { "name": "toxin activity", "id": "GO:0090729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090729", "evidence": [ { "database": "UniProtKB", "id": "Q8IPF1", "url": "https://www.uniprot.org/uniprotkb/Q8IPF1" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q8IPF1", "url": "https://www.uniprot.org/uniprotkb/Q8IPF1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IPF1-1" }, { "uniprot_canonical_ac": "Q8IPR5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IPR5", "url": "https://www.uniprot.org/uniprotkb/Q8IPR5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 323, "chemical_mass": 35498.0, "gene_names": "Dmel\\CG15594;CG15594;Dmel\\CG15594;Dmel_CG15594", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IPR5-1" }, { "uniprot_canonical_ac": "Q9VP68-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VP68", "url": "https://www.uniprot.org/uniprotkb/Q9VP68" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 446, "chemical_mass": 47074.0, "gene_names": "Dmel\\CG10512;CG10512;Dmel\\CG10512;Dmel_CG10512", "protein_name": "", "disease": [], "molecular_function": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "Q9VP68", "url": "https://www.uniprot.org/uniprotkb/Q9VP68" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VP68-1", "start_pos": "395", "end_pos": "395", "site_lbl": "Thr395", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 395, "start_aa": "Thr", "end_pos": 395, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr395", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VP68-1" }, { "uniprot_canonical_ac": "Q8IPW2-2", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 548, "chemical_mass": 60406.0, "gene_names": "dock;2L19;CG3727;DOCK;Dm0447;Dmel\\CG3727;Dock;Nck;dck;dock;doc;l(2)04723", "protein_name": "SH2/SH3 adapter protein dreadlocks", "disease": [], "biological_process": [ { "name": "negative regulation of insulin receptor signaling pathway", "id": "GO:0046627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046627", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" }, { "name": "myoblast fusion", "id": "GO:0007520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007520", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" } ], "molecular_function": [ { "name": "insulin receptor binding", "id": "GO:0005158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005158", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" }, { "name": "kinase binding", "id": "GO:0019900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019900", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" }, { "name": "male germline ring canal", "id": "GO:0035323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035323", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8IPW2-2", "start_pos": "186", "end_pos": "186", "site_lbl": "Trp186", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "K", "comment": "Probably disrupts the binding pocket of SH3 domain 1. No effect on interaction with Pak. Unable to rescue R cell projection phenotype in loss of function mutants; when associated with Q-336.", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" }, { "database": "PubMed", "id": "10399914", "url": "https://glygen.org/publication/PubMed/10399914" }, { "database": "PubMed", "id": "9482841", "url": "https://glygen.org/publication/PubMed/9482841" } ] } ] }, { "uniprot_canonical_ac": "Q8IPW2-2", "start_pos": "289", "end_pos": "289", "site_lbl": "Trp289", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "K", "comment": "Probably disrupts the binding pocket of SH3 domain 2. Disrupts interaction with Pak. Unable to rescue R cell projection phenotype in loss of function mutants.", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" }, { "database": "PubMed", "id": "10399914", "url": "https://glygen.org/publication/PubMed/10399914" }, { "database": "PubMed", "id": "9482841", "url": "https://glygen.org/publication/PubMed/9482841" } ] } ] }, { "uniprot_canonical_ac": "Q8IPW2-2", "start_pos": "363", "end_pos": "363", "site_lbl": "Trp363", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "K", "comment": "Probably disrupts the binding pocket of SH3 domain 3. No effect on interaction with Pak. Unable to rescue R cell projection phenotype in loss of function mutants; when associated with Q-336.", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" }, { "database": "PubMed", "id": "9482841", "url": "https://glygen.org/publication/PubMed/9482841" }, { "database": "PubMed", "id": "10399914", "url": "https://glygen.org/publication/PubMed/10399914" } ] } ] }, { "uniprot_canonical_ac": "Q8IPW2-2", "start_pos": "474", "end_pos": "474", "site_lbl": "Arg474", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "Q", "comment": "Probably disrupts SH2 phosphotyrosine binding pocket. Unable to rescue R cell projection phenotype in loss of function mutants; when associated with K-48 or K-225.", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" }, { "database": "PubMed", "id": "9482841", "url": "https://glygen.org/publication/PubMed/9482841" } ] } ] } ], "record_id": "Q8IPW2-2" }, { "uniprot_canonical_ac": "Q8IPX4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IPX4", "url": "https://www.uniprot.org/uniprotkb/Q8IPX4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 192, "chemical_mass": 21952.0, "gene_names": "CG16933;CG16933;CG31659;Dmel\\CG31659;Dmel_CG31659", "protein_name": "", "disease": [], "biological_process": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "Q8IPX4", "url": "https://www.uniprot.org/uniprotkb/Q8IPX4" } ], "pmid": "" }, { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "Q8IPX4", "url": "https://www.uniprot.org/uniprotkb/Q8IPX4" } ], "pmid": "" }, { "name": "response to reactive oxygen species", "id": "GO:0000302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000302", "evidence": [ { "database": "UniProtKB", "id": "Q8IPX4", "url": "https://www.uniprot.org/uniprotkb/Q8IPX4" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q8IPX4", "url": "https://www.uniprot.org/uniprotkb/Q8IPX4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q8IPX4", "url": "https://www.uniprot.org/uniprotkb/Q8IPX4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IPX4-1" }, { "uniprot_canonical_ac": "Q8IQ06-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQ06", "url": "https://www.uniprot.org/uniprotkb/Q8IQ06" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 109, "chemical_mass": 12293.0, "gene_names": "BEST:RH19272;BEST:RH19272;CG31777;Dmel\\CG31777;Dmel_CG31777", "protein_name": "BPTI/Kunitz inhibitor domain-containing protein", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ06", "url": "https://www.uniprot.org/uniprotkb/Q8IQ06" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IQ06-1" }, { "uniprot_canonical_ac": "Q8IQ79-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQ79", "url": "https://www.uniprot.org/uniprotkb/Q8IQ79" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 253, "chemical_mass": 29067.0, "gene_names": "sphinx1;CG32383;CG8555;Dmel\\CG32383;Dmel_CG32383;SPH194a;SPH194;Sphinx-1;Sphinx1;Spx1;sphinx-1;sphinx1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ79", "url": "https://www.uniprot.org/uniprotkb/Q8IQ79" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ79", "url": "https://www.uniprot.org/uniprotkb/Q8IQ79" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ79", "url": "https://www.uniprot.org/uniprotkb/Q8IQ79" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ79", "url": "https://www.uniprot.org/uniprotkb/Q8IQ79" } ], "pmid": "" }, { "name": "defense response to Gram-negative bacterium", "id": "GO:0050829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050829", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ79", "url": "https://www.uniprot.org/uniprotkb/Q8IQ79" } ], "pmid": "" }, { "name": "defense response to Gram-positive bacterium", "id": "GO:0050830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050830", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ79", "url": "https://www.uniprot.org/uniprotkb/Q8IQ79" } ], "pmid": "" }, { "name": "defense response to fungus", "id": "GO:0050832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050832", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ79", "url": "https://www.uniprot.org/uniprotkb/Q8IQ79" } ], "pmid": "" }, { "name": "mating", "id": "GO:0007618", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007618", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ79", "url": "https://www.uniprot.org/uniprotkb/Q8IQ79" } ], "pmid": "" }, { "name": "Toll receptor ligand protein activation cascade", "id": "GO:0160032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160032", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ79", "url": "https://www.uniprot.org/uniprotkb/Q8IQ79" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ79", "url": "https://www.uniprot.org/uniprotkb/Q8IQ79" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IQ79-1" }, { "uniprot_canonical_ac": "Q8IQ88-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQ88", "url": "https://www.uniprot.org/uniprotkb/Q8IQ88" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 760, "chemical_mass": 83551.0, "gene_names": "Dmel\\CG14837;CG14837;Dmel\\CG14837;Dmel_CG14837", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IQ88-1" }, { "uniprot_canonical_ac": "Q8IQ89-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQ89", "url": "https://www.uniprot.org/uniprotkb/Q8IQ89" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 291, "chemical_mass": 33062.0, "gene_names": "Dmel\\CG32376;CG32376;CG8528;Dmel\\CG32376;Dmel_CG32376;SP148b;SP148", "protein_name": "Peptidase S1 domain-containing protein", "disease": [ { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ89", "url": "https://www.uniprot.org/uniprotkb/Q8IQ89" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ89", "url": "https://www.uniprot.org/uniprotkb/Q8IQ89" } ], "pmid": "" }, { "name": "digestion", "id": "GO:0007586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007586", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ89", "url": "https://www.uniprot.org/uniprotkb/Q8IQ89" } ], "pmid": "" }, { "name": "hemolymph coagulation", "id": "GO:0042381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042381", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ89", "url": "https://www.uniprot.org/uniprotkb/Q8IQ89" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8IQ89-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Thr41", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 41, "start_aa": "Thr", "end_pos": 41, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr41", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q8IQ89-1" }, { "uniprot_canonical_ac": "Q8IQC4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQC4", "url": "https://www.uniprot.org/uniprotkb/Q8IQC4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 81, "chemical_mass": 9455.0, "gene_names": "ghi;CG32038;Dmel\\CG32038;Dmel_CG32038;fro;ghi", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q8IQC4", "url": "https://www.uniprot.org/uniprotkb/Q8IQC4" } ], "pmid": "" } ], "biological_process": [ { "name": "sphingolipid biosynthetic process", "id": "GO:0030148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030148", "evidence": [ { "database": "UniProtKB", "id": "Q8IQC4", "url": "https://www.uniprot.org/uniprotkb/Q8IQC4" } ], "pmid": "" }, { "name": "actomyosin contractile ring contraction", "id": "GO:0000916", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000916", "evidence": [ { "database": "UniProtKB", "id": "Q8IQC4", "url": "https://www.uniprot.org/uniprotkb/Q8IQC4" } ], "pmid": "" }, { "name": "meiotic spindle organization", "id": "GO:0000212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000212", "evidence": [ { "database": "UniProtKB", "id": "Q8IQC4", "url": "https://www.uniprot.org/uniprotkb/Q8IQC4" } ], "pmid": "" }, { "name": "meiosis I cytokinesis", "id": "GO:0007110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007110", "evidence": [ { "database": "UniProtKB", "id": "Q8IQC4", "url": "https://www.uniprot.org/uniprotkb/Q8IQC4" } ], "pmid": "" }, { "name": "meiosis II cytokinesis", "id": "GO:0007111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007111", "evidence": [ { "database": "UniProtKB", "id": "Q8IQC4", "url": "https://www.uniprot.org/uniprotkb/Q8IQC4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8IQC4-1", "start_pos": "62", "end_pos": "62", "site_lbl": "Thr62", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 62, "start_aa": "Thr", "end_pos": 62, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr62", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q8IQC4-1" }, { "uniprot_canonical_ac": "Q8IQE7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQE7", "url": "https://www.uniprot.org/uniprotkb/Q8IQE7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 110, "chemical_mass": 12066.0, "gene_names": "Dmel\\CG32074;CG32074;Dmel\\CG32074;Dmel_CG32074", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IQE7-1" }, { "uniprot_canonical_ac": "Q8IQJ4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IQJ4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 269, "chemical_mass": 30096.0, "gene_names": "Dmel\\CG10725;CG10725;Dmel\\CG10725;Dmel_CG10725", "protein_name": "Chitin-binding type-2 domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q8IQJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IQJ4" } ], "pmid": "" }, { "name": "external encapsulating structure", "id": "GO:0030312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030312", "evidence": [ { "database": "UniProtKB", "id": "Q8IQJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IQJ4" } ], "pmid": "" } ], "molecular_function": [ { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "Q8IQJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IQJ4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IQJ4-1" }, { "uniprot_canonical_ac": "Q8IQY1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQY1", "url": "https://www.uniprot.org/uniprotkb/Q8IQY1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 104, "chemical_mass": 11952.0, "gene_names": "Dmel\\CG32551;CG32551;Dmel\\CG32551;Dmel_CG32551", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IQY1-1" }, { "uniprot_canonical_ac": "Q8IQZ4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQZ4", "url": "https://www.uniprot.org/uniprotkb/Q8IQZ4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 239, "chemical_mass": 27082.0, "gene_names": "CG7871;CG32554;CG7871;Dmel\\CG32554;Dmel_CG32554", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IQZ4-1" }, { "uniprot_canonical_ac": "Q8IR50-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IR50", "url": "https://www.uniprot.org/uniprotkb/Q8IR50" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 262, "chemical_mass": 28863.0, "gene_names": "betaNACtes6;CG32598;Dmel\\CG32598;Dmel_CG32598;bNACtes6;betaNACtes6", "protein_name": "Transcription factor BTF3", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q8IR50", "url": "https://www.uniprot.org/uniprotkb/Q8IR50" } ], "pmid": "" }, { "name": "nascent polypeptide-associated complex", "id": "GO:0005854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005854", "evidence": [ { "database": "UniProtKB", "id": "Q8IR50", "url": "https://www.uniprot.org/uniprotkb/Q8IR50" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IR50-1" }, { "uniprot_canonical_ac": "Q8IR73-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IR73", "url": "https://www.uniprot.org/uniprotkb/Q8IR73" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 101, "chemical_mass": 11535.0, "gene_names": "Dmel\\CG32643;CG32643;Dmel\\CG32643;Dmel_CG32643;NEST:bs08h10", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IR73-1" }, { "uniprot_canonical_ac": "Q8IRA7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IRA7", "url": "https://www.uniprot.org/uniprotkb/Q8IRA7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 565, "chemical_mass": 66380.0, "gene_names": "Dmel\\CG32246;CG32246;Dmel\\CG32246;Dmel_CG32246", "protein_name": "Nucleoporin Ndc1", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8IRA7-1", "start_pos": "417", "end_pos": "417", "site_lbl": "Thr417", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 417, "start_aa": "Thr", "end_pos": 417, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr417", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q8IRA7-1" }, { "uniprot_canonical_ac": "Q8IRB3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IRB3", "url": "https://www.uniprot.org/uniprotkb/Q8IRB3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 415, "chemical_mass": 45017.0, "gene_names": "Dmel\\CG32241;CG32241;Dmel\\CG32241;Dmel_CG32241", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8IRB3-1", "start_pos": "390", "end_pos": "390", "site_lbl": "Thr390", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 390, "start_aa": "Thr", "end_pos": 390, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr390", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q8IRB3-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Thr68", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 68, "start_aa": "Thr", "end_pos": 68, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr68", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q8IRB3-1" }, { "uniprot_canonical_ac": "Q8IRD1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IRD1", "url": "https://www.uniprot.org/uniprotkb/Q8IRD1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 717, "chemical_mass": 80236.0, "gene_names": "Dmel\\CG12010;CG12010;Dmel\\CG12010;Dmel_CG12010", "protein_name": "AAA+ ATPase domain-containing protein", "disease": [ { "disease_id": "DOID:0050565", "name": "autosomal recessive nonsyndromic deafness", "description": "A nonsyndromic deafness characterized by an autosomal recessive inheritance mode.", "url": "https://disease-ontology.org/term/DOID:0050565", "evidence": [ { "id": "0050565", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050565" } ], "weight": 0.0 } ], "biological_process": [ { "name": "autophagosome maturation", "id": "GO:0097352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097352", "evidence": [ { "database": "UniProtKB", "id": "Q8IRD1", "url": "https://www.uniprot.org/uniprotkb/Q8IRD1" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "Q8IRD1", "url": "https://www.uniprot.org/uniprotkb/Q8IRD1" } ], "pmid": "" }, { "name": "mitotic spindle disassembly", "id": "GO:0051228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051228", "evidence": [ { "database": "UniProtKB", "id": "Q8IRD1", "url": "https://www.uniprot.org/uniprotkb/Q8IRD1" } ], "pmid": "" }, { "name": "retrograde protein transport, ER to cytosol", "id": "GO:0030970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030970", "evidence": [ { "database": "UniProtKB", "id": "Q8IRD1", "url": "https://www.uniprot.org/uniprotkb/Q8IRD1" } ], "pmid": "" } ], "cellular_component": [ { "name": "VCP-NPL4-UFD1 AAA ATPase complex", "id": "GO:0034098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034098", "evidence": [ { "database": "UniProtKB", "id": "Q8IRD1", "url": "https://www.uniprot.org/uniprotkb/Q8IRD1" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q8IRD1", "url": "https://www.uniprot.org/uniprotkb/Q8IRD1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q8IRD1", "url": "https://www.uniprot.org/uniprotkb/Q8IRD1" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q8IRD1", "url": "https://www.uniprot.org/uniprotkb/Q8IRD1" } ], "pmid": "" }, { "name": "polyubiquitin modification-dependent protein binding", "id": "GO:0031593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031593", "evidence": [ { "database": "UniProtKB", "id": "Q8IRD1", "url": "https://www.uniprot.org/uniprotkb/Q8IRD1" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q8IRD1", "url": "https://www.uniprot.org/uniprotkb/Q8IRD1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8IRD1-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Thr55", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 55, "start_aa": "Thr", "end_pos": 55, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr55", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q8IRD1-1" }, { "uniprot_canonical_ac": "Q8IRF5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IRF5", "url": "https://www.uniprot.org/uniprotkb/Q8IRF5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1164, "chemical_mass": 133110.0, "gene_names": "CG8970;AC;CG32305;CG8970;Dmel\\CG32305;Dmel_CG32305", "protein_name": "adenylate cyclase", "disease": [ { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:3312", "name": "bipolar disorder", "description": "A mood disorder that involves alternating periods of mania and depression.", "url": "https://disease-ontology.org/term/DOID:3312", "evidence": [ { "id": "3312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3312" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "adenylate cyclase activity", "id": "GO:0004016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004016", "evidence": [ { "database": "UniProtKB", "id": "Q8IRF5", "url": "https://www.uniprot.org/uniprotkb/Q8IRF5" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q8IRF5", "url": "https://www.uniprot.org/uniprotkb/Q8IRF5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q8IRF5", "url": "https://www.uniprot.org/uniprotkb/Q8IRF5" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q8IRF5", "url": "https://www.uniprot.org/uniprotkb/Q8IRF5" } ], "pmid": "" } ], "biological_process": [ { "name": "cAMP biosynthetic process", "id": "GO:0006171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006171", "evidence": [ { "database": "UniProtKB", "id": "Q8IRF5", "url": "https://www.uniprot.org/uniprotkb/Q8IRF5" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "Q8IRF5", "url": "https://www.uniprot.org/uniprotkb/Q8IRF5" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "Q8IRF5", "url": "https://www.uniprot.org/uniprotkb/Q8IRF5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IRF5-1" }, { "uniprot_canonical_ac": "Q8IRH3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IRH3", "url": "https://www.uniprot.org/uniprotkb/Q8IRH3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 767, "chemical_mass": 90219.0, "gene_names": "Dmel\\CG32320;CG32320;Dmel\\CG32320;Dmel_CG32320", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q8IRH3", "url": "https://www.uniprot.org/uniprotkb/Q8IRH3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IRH3-1" }, { "uniprot_canonical_ac": "Q8IRK9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IRK9", "url": "https://www.uniprot.org/uniprotkb/Q8IRK9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 197, "chemical_mass": 22845.0, "gene_names": "Rab9D;CG32678;Dmel\\CG32678;Dmel_CG32678;Rab9D;anon-AE003451.1", "protein_name": "", "disease": [], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q8IRK9", "url": "https://www.uniprot.org/uniprotkb/Q8IRK9" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q8IRK9", "url": "https://www.uniprot.org/uniprotkb/Q8IRK9" } ], "pmid": "" } ], "cellular_component": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "Q8IRK9", "url": "https://www.uniprot.org/uniprotkb/Q8IRK9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q8IRK9", "url": "https://www.uniprot.org/uniprotkb/Q8IRK9" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "Q8IRK9", "url": "https://www.uniprot.org/uniprotkb/Q8IRK9" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "Q8IRK9", "url": "https://www.uniprot.org/uniprotkb/Q8IRK9" } ], "pmid": "" }, { "name": "trans-Golgi network transport vesicle", "id": "GO:0030140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030140", "evidence": [ { "database": "UniProtKB", "id": "Q8IRK9", "url": "https://www.uniprot.org/uniprotkb/Q8IRK9" } ], "pmid": "" } ], "biological_process": [ { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "Q8IRK9", "url": "https://www.uniprot.org/uniprotkb/Q8IRK9" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "Q8IRK9", "url": "https://www.uniprot.org/uniprotkb/Q8IRK9" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "Q8IRK9", "url": "https://www.uniprot.org/uniprotkb/Q8IRK9" } ], "pmid": "" }, { "name": "Rab protein signal transduction", "id": "GO:0032482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032482", "evidence": [ { "database": "UniProtKB", "id": "Q8IRK9", "url": "https://www.uniprot.org/uniprotkb/Q8IRK9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IRK9-1" }, { "uniprot_canonical_ac": "Q8IRL0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IRL0", "url": "https://www.uniprot.org/uniprotkb/Q8IRL0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1506, "chemical_mass": 169458.0, "gene_names": "Dmel\\CG32681;CG32681;Dmel\\CG32681;Dmel_CG32681", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IRL0-1" }, { "uniprot_canonical_ac": "Q8MLP8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8MLP8", "url": "https://www.uniprot.org/uniprotkb/Q8MLP8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 247, "chemical_mass": 28183.0, "gene_names": "Not11;C2orf29;CG13567;Dmel\\CG13567;Dmel_CG13567;NOT11;Not11", "protein_name": "CCR4-NOT transcription complex subunit 11", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q8MLP8", "url": "https://www.uniprot.org/uniprotkb/Q8MLP8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q8MLP8", "url": "https://www.uniprot.org/uniprotkb/Q8MLP8" } ], "pmid": "" }, { "name": "CCR4-NOT complex", "id": "GO:0030014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030014", "evidence": [ { "database": "UniProtKB", "id": "Q8MLP8", "url": "https://www.uniprot.org/uniprotkb/Q8MLP8" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q8MLP8", "url": "https://www.uniprot.org/uniprotkb/Q8MLP8" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q8MLP8", "url": "https://www.uniprot.org/uniprotkb/Q8MLP8" } ], "pmid": "" }, { "name": "negative regulation of translation", "id": "GO:0017148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017148", "evidence": [ { "database": "UniProtKB", "id": "Q8MLP8", "url": "https://www.uniprot.org/uniprotkb/Q8MLP8" } ], "pmid": "" }, { "name": "mRNA catabolic process", "id": "GO:0006402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006402", "evidence": [ { "database": "UniProtKB", "id": "Q8MLP8", "url": "https://www.uniprot.org/uniprotkb/Q8MLP8" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated gene silencing", "id": "GO:0031047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031047", "evidence": [ { "database": "UniProtKB", "id": "Q8MLP8", "url": "https://www.uniprot.org/uniprotkb/Q8MLP8" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA poly(A) tail shortening", "id": "GO:0000289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000289", "evidence": [ { "database": "UniProtKB", "id": "Q8MLP8", "url": "https://www.uniprot.org/uniprotkb/Q8MLP8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8MLP8-1" }, { "uniprot_canonical_ac": "Q8MLS3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8MLS3", "url": "https://www.uniprot.org/uniprotkb/Q8MLS3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 122, "chemical_mass": 12825.0, "gene_names": "Dmel\\CG30413;CG30413;Dmel\\CG30413;Dmel_CG30413", "protein_name": "Salivary secreted peptide", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8MLS3-1" }, { "uniprot_canonical_ac": "Q8MLU9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8MLU9", "url": "https://www.uniprot.org/uniprotkb/Q8MLU9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2979, "chemical_mass": 321313.0, "gene_names": "Dmel\\CG13492;CG13492;Dmel\\CG13492;Dmel_CG13492", "protein_name": "DUF753 domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8MLU9-1" }, { "uniprot_canonical_ac": "Q8MMD6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8MMD6", "url": "https://www.uniprot.org/uniprotkb/Q8MMD6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 497, "chemical_mass": 54835.0, "gene_names": "MFS1;CG11682;CG30272;Dmel\\CG30272;Dmel_CG30272;MFS1", "protein_name": "Putative inorganic phosphate cotransporter", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q8MMD6", "url": "https://www.uniprot.org/uniprotkb/Q8MMD6" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "Q8MMD6", "url": "https://www.uniprot.org/uniprotkb/Q8MMD6" } ], "pmid": "" }, { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "Q8MMD6", "url": "https://www.uniprot.org/uniprotkb/Q8MMD6" } ], "pmid": "" } ], "biological_process": [ { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "Q8MMD6", "url": "https://www.uniprot.org/uniprotkb/Q8MMD6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8MMD6-1" }, { "uniprot_canonical_ac": "Q9I7L3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9I7L3", "url": "https://www.uniprot.org/uniprotkb/Q9I7L3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 211, "chemical_mass": 23891.0, "gene_names": "Dmel\\CG17917;CG17917;Dmel\\CG17917;Dmel_CG17917", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9I7L3", "url": "https://www.uniprot.org/uniprotkb/Q9I7L3" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of ERK1 and ERK2 cascade", "id": "GO:0070373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070373", "evidence": [ { "database": "UniProtKB", "id": "Q9I7L3", "url": "https://www.uniprot.org/uniprotkb/Q9I7L3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9I7L3-1" }, { "uniprot_canonical_ac": "Q9I7M8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9I7M8", "url": "https://www.uniprot.org/uniprotkb/Q9I7M8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 699, "chemical_mass": 79823.0, "gene_names": "Ku80;BG:DS09217.6;CG18801;DmKu80;Dmel\\CG18801;Dmel_CG18801;KU80;Ku80;Ku;ku80", "protein_name": "ATP-dependent DNA helicase II subunit 2", "disease": [ { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1749", "name": "squamous cell carcinoma", "description": "A carcinoma that derives_from squamous epithelial cells.", "url": "https://disease-ontology.org/term/DOID:1749", "evidence": [ { "id": "1749", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1749" } ], "weight": 0.0 }, { "disease_id": "DOID:1993", "name": "rectum cancer", "description": "A colorectal cancer that is located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:1993", "evidence": [ { "id": "1993", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1993" } ], "weight": 0.0 }, { "disease_id": "DOID:2513", "name": "basal cell carcinoma", "description": "A skin carcinoma affecting basal cells.", "url": "https://disease-ontology.org/term/DOID:2513", "evidence": [ { "id": "2513", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2513" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:9538", "name": "multiple myeloma", "description": "A myeloid neoplasm that is located_in the plasma cells in bone marrow.", "url": "https://disease-ontology.org/term/DOID:9538", "evidence": [ { "id": "9538", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9538" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9I7M8", "url": "https://www.uniprot.org/uniprotkb/Q9I7M8" } ], "pmid": "" }, { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "Q9I7M8", "url": "https://www.uniprot.org/uniprotkb/Q9I7M8" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q9I7M8", "url": "https://www.uniprot.org/uniprotkb/Q9I7M8" } ], "pmid": "" }, { "name": "telomeric DNA binding", "id": "GO:0042162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042162", "evidence": [ { "database": "UniProtKB", "id": "Q9I7M8", "url": "https://www.uniprot.org/uniprotkb/Q9I7M8" } ], "pmid": "" }, { "name": "DNA helicase activity", "id": "GO:0003678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003678", "evidence": [ { "database": "UniProtKB", "id": "Q9I7M8", "url": "https://www.uniprot.org/uniprotkb/Q9I7M8" } ], "pmid": "" }, { "name": "ATP-dependent activity, acting on DNA", "id": "GO:0008094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008094", "evidence": [ { "database": "UniProtKB", "id": "Q9I7M8", "url": "https://www.uniprot.org/uniprotkb/Q9I7M8" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "Q9I7M8", "url": "https://www.uniprot.org/uniprotkb/Q9I7M8" } ], "pmid": "" }, { "name": "response to ethanol", "id": "GO:0045471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045471", "evidence": [ { "database": "UniProtKB", "id": "Q9I7M8", "url": "https://www.uniprot.org/uniprotkb/Q9I7M8" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "Q9I7M8", "url": "https://www.uniprot.org/uniprotkb/Q9I7M8" } ], "pmid": "" }, { "name": "double-strand break repair via nonhomologous end joining", "id": "GO:0006303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006303", "evidence": [ { "database": "UniProtKB", "id": "Q9I7M8", "url": "https://www.uniprot.org/uniprotkb/Q9I7M8" } ], "pmid": "" } ], "cellular_component": [ { "name": "Ku70:Ku80 complex", "id": "GO:0043564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043564", "evidence": [ { "database": "UniProtKB", "id": "Q9I7M8", "url": "https://www.uniprot.org/uniprotkb/Q9I7M8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9I7M8-1" }, { "uniprot_canonical_ac": "Q9V3R0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V3R0", "url": "https://www.uniprot.org/uniprotkb/Q9V3R0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 254, "chemical_mass": 29030.0, "gene_names": "BG:BACR44L22.6;BG:BACR44L22.6;CG7631;Dmel\\CG7631;Dmel_CG7631", "protein_name": "Metalloendopeptidase", "disease": [], "molecular_function": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "Q9V3R0", "url": "https://www.uniprot.org/uniprotkb/Q9V3R0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9V3R0", "url": "https://www.uniprot.org/uniprotkb/Q9V3R0" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9V3R0", "url": "https://www.uniprot.org/uniprotkb/Q9V3R0" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9V3R0", "url": "https://www.uniprot.org/uniprotkb/Q9V3R0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V3R0-1" }, { "uniprot_canonical_ac": "Q9V3Y0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V3Y0", "url": "https://www.uniprot.org/uniprotkb/Q9V3Y0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 215, "chemical_mass": 24244.0, "gene_names": "Ankrd49;Ankrd49;BG:DS00929.2;C3;CG4140;DAnkrd49;Dmel\\CG4140;br10;l(2)35Be;l(2)br10", "protein_name": "Ankyrin repeat domain-containing protein 49", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9V3Y0", "url": "https://www.uniprot.org/uniprotkb/Q9V3Y0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9V3Y0", "url": "https://www.uniprot.org/uniprotkb/Q9V3Y0" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of establishment of planar polarity", "id": "GO:0090175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090175", "evidence": [ { "database": "UniProtKB", "id": "Q9V3Y0", "url": "https://www.uniprot.org/uniprotkb/Q9V3Y0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9V3Y0-1", "start_pos": "156", "end_pos": "156", "site_lbl": "Ala156", "weight": 0.0, "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "T", "comment": "Lethal. Pupal wings containing clones display reduced levels of dsh, reduced asymmetric localization of stan, delayed trichome initiation, and formation of trichomes in the cell center rather than at the distal cell edge; when associated with A-87.", "evidence": [ { "database": "UniProtKB", "id": "Q9V3Y0", "url": "https://www.uniprot.org/uniprotkb/Q9V3Y0" }, { "database": "PubMed", "id": "32750048", "url": "https://glygen.org/publication/PubMed/32750048" } ] } ] }, { "uniprot_canonical_ac": "Q9V3Y0-1", "start_pos": "87", "end_pos": "87", "site_lbl": "His87", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "Y", "comment": "Lethal. Pupal wings containing clones display reduced levels of dsh, reduced asymmetric localization of stan, delayed trichome initiation, and formation of trichomes in the cell center rather than at the distal cell edge; when associated with T-156.", "evidence": [ { "database": "UniProtKB", "id": "Q9V3Y0", "url": "https://www.uniprot.org/uniprotkb/Q9V3Y0" }, { "database": "PubMed", "id": "32750048", "url": "https://glygen.org/publication/PubMed/32750048" } ] } ] } ], "record_id": "Q9V3Y0-1" }, { "uniprot_canonical_ac": "Q9V421-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V421", "url": "https://www.uniprot.org/uniprotkb/Q9V421" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 253, "chemical_mass": 29304.0, "gene_names": "BG:BACR44L22.3;BACR44L22.3;BG:BACR44L22.3;CG15253;Dmel\\CG15253;Dmel_CG15253", "protein_name": "Metalloendopeptidase", "disease": [], "molecular_function": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "Q9V421", "url": "https://www.uniprot.org/uniprotkb/Q9V421" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9V421", "url": "https://www.uniprot.org/uniprotkb/Q9V421" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9V421", "url": "https://www.uniprot.org/uniprotkb/Q9V421" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9V421", "url": "https://www.uniprot.org/uniprotkb/Q9V421" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V421-1" }, { "uniprot_canonical_ac": "Q9V9P0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V9P0", "url": "https://www.uniprot.org/uniprotkb/Q9V9P0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 390, "chemical_mass": 44184.0, "gene_names": "Dmel\\CG6675;CG6675;Dmel\\CG6675;Dmel_CG6675", "protein_name": "Lipase domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9V9P0", "url": "https://www.uniprot.org/uniprotkb/Q9V9P0" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9V9P0", "url": "https://www.uniprot.org/uniprotkb/Q9V9P0" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipase activity", "id": "GO:0016298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016298", "evidence": [ { "database": "UniProtKB", "id": "Q9V9P0", "url": "https://www.uniprot.org/uniprotkb/Q9V9P0" } ], "pmid": "" }, { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "Q9V9P0", "url": "https://www.uniprot.org/uniprotkb/Q9V9P0" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "Q9V9P0", "url": "https://www.uniprot.org/uniprotkb/Q9V9P0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V9P0-1" }, { "uniprot_canonical_ac": "Q9V9Q1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V9Q1", "url": "https://www.uniprot.org/uniprotkb/Q9V9Q1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 631, "chemical_mass": 73056.0, "gene_names": "gi7302136;CG11630;Dmel\\CG11630;Dmel_CG11630;gi7302136", "protein_name": "", "disease": [], "biological_process": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "Q9V9Q1", "url": "https://www.uniprot.org/uniprotkb/Q9V9Q1" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9V9Q1", "url": "https://www.uniprot.org/uniprotkb/Q9V9Q1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V9Q1-1" }, { "uniprot_canonical_ac": "Q9V9V4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V9V4", "url": "https://www.uniprot.org/uniprotkb/Q9V9V4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 298, "chemical_mass": 34834.0, "gene_names": "Dmel\\CG11550;CG11550;Dmel\\CG11550;Dmel_CG11550", "protein_name": "CRAL-TRIO domain-containing protein", "disease": [], "molecular_function": [ { "name": "phosphatidylinositol bisphosphate binding", "id": "GO:1902936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902936", "evidence": [ { "database": "UniProtKB", "id": "Q9V9V4", "url": "https://www.uniprot.org/uniprotkb/Q9V9V4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V9V4-1" }, { "uniprot_canonical_ac": "Q9V9W5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V9W5", "url": "https://www.uniprot.org/uniprotkb/Q9V9W5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 443, "chemical_mass": 50266.0, "gene_names": "Dmel\\CG1638;CG1638;Dmel\\CG1638;Dmel_CG1638;bs31f06.y1", "protein_name": "HotDog ACOT-type domain-containing protein", "disease": [], "molecular_function": [ { "name": "acetyl-CoA hydrolase activity", "id": "GO:0003986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003986", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W5", "url": "https://www.uniprot.org/uniprotkb/Q9V9W5" } ], "pmid": "" }, { "name": "fatty acyl-CoA hydrolase activity", "id": "GO:0047617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047617", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W5", "url": "https://www.uniprot.org/uniprotkb/Q9V9W5" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W5", "url": "https://www.uniprot.org/uniprotkb/Q9V9W5" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W5", "url": "https://www.uniprot.org/uniprotkb/Q9V9W5" } ], "pmid": "" } ], "biological_process": [ { "name": "acyl-CoA metabolic process", "id": "GO:0006637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006637", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W5", "url": "https://www.uniprot.org/uniprotkb/Q9V9W5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V9W5-1" }, { "uniprot_canonical_ac": "Q9V9W7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2089, "chemical_mass": 239692.0, "gene_names": "rod;CG1569;Dmel\\CG1569;Dmel_CG1569;EP3408;ROD;Rod1;Rod;pNB20A;rod", "protein_name": "", "disease": [], "cellular_component": [ { "name": "kinetochore microtubule", "id": "GO:0005828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005828", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" }, { "name": "RZZ complex", "id": "GO:1990423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990423", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" }, { "name": "spindle midzone", "id": "GO:0051233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051233", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" }, { "name": "Golgi stack", "id": "GO:0005795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005795", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" }, { "name": "acroblast", "id": "GO:0036063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036063", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of chromosome separation", "id": "GO:1905818", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905818", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" }, { "name": "protein localization to kinetochore involved in kinetochore assembly", "id": "GO:1903394", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903394", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" }, { "name": "mitotic spindle assembly checkpoint signaling", "id": "GO:0007094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007094", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" }, { "name": "regulation of attachment of spindle microtubules to kinetochore", "id": "GO:0051988", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051988", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" }, { "name": "regulation of mitotic metaphase/anaphase transition", "id": "GO:0030071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030071", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" }, { "name": "mitotic sister chromatid segregation", "id": "GO:0000070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000070", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" }, { "name": "protein localization to kinetochore", "id": "GO:0034501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034501", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" } ], "molecular_function": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V9W7-1" }, { "uniprot_canonical_ac": "Q9V9Y8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V9Y8", "url": "https://www.uniprot.org/uniprotkb/Q9V9Y8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 298, "chemical_mass": 33487.0, "gene_names": "CAH6;CAH6;CG3669;Dmel\\CG3669;Dmel_CG3669", "protein_name": "Carbonic anhydrase", "disease": [ { "disease_id": "DOID:0050861", "name": "colorectal adenocarcinoma", "description": "A colorectal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:0050861", "evidence": [ { "id": "0050861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050861" } ], "weight": 0.0 }, { "disease_id": "DOID:0050997", "name": "cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome", "description": "A syndrome characterized by congenital onset of nonprogressive cerebellar ataxia, disturbed equilibrium, and mental retardation, associated with cerebellar hypoplasia.", "url": "https://disease-ontology.org/term/DOID:0050997", "evidence": [ { "id": "0050997", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050997" } ], "weight": 0.0 }, { "disease_id": "DOID:0080199", "name": "colorectal carcinoma", "description": "A colorectal cancer that arises from the colon or rectum and invades through the muscularis mucosa into the submucosa.", "url": "https://disease-ontology.org/term/DOID:0080199", "evidence": [ { "id": "0080199", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080199" } ], "weight": 0.0 }, { "disease_id": "DOID:0111371", "name": "isolated hyperchlorhidrosis", "description": "A skin disease characterized by excessive loss of salt in sweat resulting in low levels of salt in the blood in the absence of other symptoms that has_material_basis_in homozygous or compound heterozygous mutation in the CA12 gene on chromosome 15q22.2.", "url": "https://disease-ontology.org/term/DOID:0111371", "evidence": [ { "id": "0111371", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111371" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:234", "name": "colon adenocarcinoma", "description": "A colon carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:234", "evidence": [ { "id": "234", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:234" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:3883", "name": "Lynch syndrome", "description": "A syndrome that is characterized by an increased risk for colon cancer and cancers of the endometrium, ovary, stomach, small intestine, hepatobiliary tract, urinary tract, brain, and skin and has_material_basis_in mutation of mismatch repair genes that increases the risk of many types of cancers.", "url": "https://disease-ontology.org/term/DOID:3883", "evidence": [ { "id": "3883", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3883" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:5015", "name": "fibrolamellar carcinoma", "description": "A hepatocellular carcinoma characterized microscopically by laminated fibrous layers interspersed between the tumour cells. The polygonal, deeply eosinophilic tumor cells arise in non-cirrhotic livers.", "url": "https://disease-ontology.org/term/DOID:5015", "evidence": [ { "id": "5015", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5015" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9V9Y8", "url": "https://www.uniprot.org/uniprotkb/Q9V9Y8" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9V9Y8", "url": "https://www.uniprot.org/uniprotkb/Q9V9Y8" } ], "pmid": "" }, { "name": "carbonate dehydratase activity", "id": "GO:0004089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004089", "evidence": [ { "database": "UniProtKB", "id": "Q9V9Y8", "url": "https://www.uniprot.org/uniprotkb/Q9V9Y8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V9Y8-1" }, { "uniprot_canonical_ac": "Q9VA61-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VA61", "url": "https://www.uniprot.org/uniprotkb/Q9VA61" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 542, "chemical_mass": 62120.0, "gene_names": "PH4alphaNE2;CG9720;Dmel\\CG9720;Dmel_CG9720;PH4-alpha-NE2;PH4alphaNE2", "protein_name": "procollagen-proline 4-dioxygenase", "disease": [ { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9VA61", "url": "https://www.uniprot.org/uniprotkb/Q9VA61" } ], "pmid": "" }, { "name": "L-ascorbic acid binding", "id": "GO:0031418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031418", "evidence": [ { "database": "UniProtKB", "id": "Q9VA61", "url": "https://www.uniprot.org/uniprotkb/Q9VA61" } ], "pmid": "" }, { "name": "procollagen-proline 4-dioxygenase activity", "id": "GO:0004656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004656", "evidence": [ { "database": "UniProtKB", "id": "Q9VA61", "url": "https://www.uniprot.org/uniprotkb/Q9VA61" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VA61", "url": "https://www.uniprot.org/uniprotkb/Q9VA61" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q9VA61", "url": "https://www.uniprot.org/uniprotkb/Q9VA61" } ], "pmid": "" }, { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "Q9VA61", "url": "https://www.uniprot.org/uniprotkb/Q9VA61" } ], "pmid": "" } ], "biological_process": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "Q9VA61", "url": "https://www.uniprot.org/uniprotkb/Q9VA61" } ], "pmid": "" }, { "name": "mating", "id": "GO:0007618", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007618", "evidence": [ { "database": "UniProtKB", "id": "Q9VA61", "url": "https://www.uniprot.org/uniprotkb/Q9VA61" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VA61-1" }, { "uniprot_canonical_ac": "Q9VA77-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VA77", "url": "https://www.uniprot.org/uniprotkb/Q9VA77" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 666, "chemical_mass": 75264.0, "gene_names": "Dmel\\CG15534;CG15534;Dmel\\CG15534;Dmel_CG15534;aSMase;alphaSmase", "protein_name": "Sphingomyelin phosphodiesterase", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VA77", "url": "https://www.uniprot.org/uniprotkb/Q9VA77" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VA77", "url": "https://www.uniprot.org/uniprotkb/Q9VA77" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "Q9VA77", "url": "https://www.uniprot.org/uniprotkb/Q9VA77" } ], "pmid": "" } ], "biological_process": [ { "name": "ceramide biosynthetic process", "id": "GO:0046513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046513", "evidence": [ { "database": "UniProtKB", "id": "Q9VA77", "url": "https://www.uniprot.org/uniprotkb/Q9VA77" } ], "pmid": "" }, { "name": "sphingomyelin catabolic process", "id": "GO:0006685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006685", "evidence": [ { "database": "UniProtKB", "id": "Q9VA77", "url": "https://www.uniprot.org/uniprotkb/Q9VA77" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VA77", "url": "https://www.uniprot.org/uniprotkb/Q9VA77" } ], "pmid": "" }, { "name": "hydrolase activity, acting on glycosyl bonds", "id": "GO:0016798", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016798", "evidence": [ { "database": "UniProtKB", "id": "Q9VA77", "url": "https://www.uniprot.org/uniprotkb/Q9VA77" } ], "pmid": "" }, { "name": "acid sphingomyelin phosphodiesterase activity", "id": "GO:0061750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061750", "evidence": [ { "database": "UniProtKB", "id": "Q9VA77", "url": "https://www.uniprot.org/uniprotkb/Q9VA77" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VA77-1" }, { "uniprot_canonical_ac": "Q9VAN1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VAN1", "url": "https://www.uniprot.org/uniprotkb/Q9VAN1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 168, "chemical_mass": 18884.0, "gene_names": "Dmel\\CG14515;CG14515;Dmel\\CG14515;Dmel_CG14515", "protein_name": "Reelin domain-containing protein", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VAN1", "url": "https://www.uniprot.org/uniprotkb/Q9VAN1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VAN1-1" }, { "uniprot_canonical_ac": "Q9VAQ9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VAQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VAQ9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 414, "chemical_mass": 46367.0, "gene_names": "Ssl2;CG11833;DmSSl2;Dmel\\CG11833;Dmel_CG11833;SSl2;Ssl2", "protein_name": "", "disease": [], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q9VAQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VAQ9" } ], "pmid": "" }, { "name": "arylesterase activity", "id": "GO:0004064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004064", "evidence": [ { "database": "UniProtKB", "id": "Q9VAQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VAQ9" } ], "pmid": "" }, { "name": "lyase activity", "id": "GO:0016829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016829", "evidence": [ { "database": "UniProtKB", "id": "Q9VAQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VAQ9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VAQ9-1" }, { "uniprot_canonical_ac": "Q9VAV6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VAV6", "url": "https://www.uniprot.org/uniprotkb/Q9VAV6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 421, "chemical_mass": 48425.0, "gene_names": "Myst5;CG1894;Dmel\\CG1894;Dmel_CG1894;HAT;dmHAG407", "protein_name": "Histone acetyltransferase", "disease": [ { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:4467", "name": "clear cell renal cell carcinoma", "description": "A renal cell carcinoma that has_material_basis_in cells that appear very pale or clear when examined under microscope.", "url": "https://disease-ontology.org/term/DOID:4467", "evidence": [ { "id": "4467", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4467" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV6", "url": "https://www.uniprot.org/uniprotkb/Q9VAV6" } ], "pmid": "" }, { "name": "NuA4 histone acetyltransferase complex", "id": "GO:0035267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035267", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV6", "url": "https://www.uniprot.org/uniprotkb/Q9VAV6" } ], "pmid": "" }, { "name": "euchromatin", "id": "GO:0000791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000791", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV6", "url": "https://www.uniprot.org/uniprotkb/Q9VAV6" } ], "pmid": "" }, { "name": "MSL complex", "id": "GO:0072487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072487", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV6", "url": "https://www.uniprot.org/uniprotkb/Q9VAV6" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV6", "url": "https://www.uniprot.org/uniprotkb/Q9VAV6" } ], "pmid": "" }, { "name": "NSL complex", "id": "GO:0044545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044545", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV6", "url": "https://www.uniprot.org/uniprotkb/Q9VAV6" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV6", "url": "https://www.uniprot.org/uniprotkb/Q9VAV6" } ], "pmid": "" } ], "molecular_function": [ { "name": "histone acetyltransferase activity", "id": "GO:0004402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004402", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV6", "url": "https://www.uniprot.org/uniprotkb/Q9VAV6" } ], "pmid": "" }, { "name": "histone H4K16 acetyltransferase activity", "id": "GO:0046972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046972", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV6", "url": "https://www.uniprot.org/uniprotkb/Q9VAV6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VAV6-1" }, { "uniprot_canonical_ac": "Q9VAW1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VAW1", "url": "https://www.uniprot.org/uniprotkb/Q9VAW1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 970, "chemical_mass": 112796.0, "gene_names": "Moca-cyp;BEST:LD38313;CG1866;Dmel\\CG1866;Dmel_CG1866;Moca-cyp;anon-WO0147981.13;anon-WO0147981.4;anon-WO0147981.5;moca", "protein_name": "peptidylprolyl isomerase", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VAW1", "url": "https://www.uniprot.org/uniprotkb/Q9VAW1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q9VAW1", "url": "https://www.uniprot.org/uniprotkb/Q9VAW1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VAW1", "url": "https://www.uniprot.org/uniprotkb/Q9VAW1" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "Q9VAW1", "url": "https://www.uniprot.org/uniprotkb/Q9VAW1" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "Q9VAW1", "url": "https://www.uniprot.org/uniprotkb/Q9VAW1" } ], "pmid": "" } ], "biological_process": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "Q9VAW1", "url": "https://www.uniprot.org/uniprotkb/Q9VAW1" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q9VAW1", "url": "https://www.uniprot.org/uniprotkb/Q9VAW1" } ], "pmid": "" } ], "molecular_function": [ { "name": "cyclosporin A binding", "id": "GO:0016018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016018", "evidence": [ { "database": "UniProtKB", "id": "Q9VAW1", "url": "https://www.uniprot.org/uniprotkb/Q9VAW1" } ], "pmid": "" }, { "name": "peptidyl-prolyl cis-trans isomerase activity", "id": "GO:0003755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003755", "evidence": [ { "database": "UniProtKB", "id": "Q9VAW1", "url": "https://www.uniprot.org/uniprotkb/Q9VAW1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VAW1-1" }, { "uniprot_canonical_ac": "Q9VB06-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VB06", "url": "https://www.uniprot.org/uniprotkb/Q9VB06" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 398, "chemical_mass": 45842.0, "gene_names": "HSPBAP1;CG12879;CG43320;Dmel\\CG43320;Dmel_CG43320;HSPBAP1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VB06", "url": "https://www.uniprot.org/uniprotkb/Q9VB06" } ], "pmid": "" } ], "molecular_function": [ { "name": "2-oxoglutarate-dependent dioxygenase activity", "id": "GO:0016706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016706", "evidence": [ { "database": "UniProtKB", "id": "Q9VB06", "url": "https://www.uniprot.org/uniprotkb/Q9VB06" } ], "pmid": "" } ], "biological_process": [ { "name": "circadian behavior", "id": "GO:0048512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048512", "evidence": [ { "database": "UniProtKB", "id": "Q9VB06", "url": "https://www.uniprot.org/uniprotkb/Q9VB06" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VB06-1" }, { "uniprot_canonical_ac": "Q9VB32-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VB32", "url": "https://www.uniprot.org/uniprotkb/Q9VB32" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 898, "chemical_mass": 103537.0, "gene_names": "Dmel\\CG13978;CG13978;Dmel\\CG13978;Dmel_CG13978", "protein_name": "GPI ethanolamine phosphate transferase 1", "disease": [ { "disease_id": "DOID:0080138", "name": "multiple congenital anomalies-hypotonia-seizures syndrome 1", "description": "A multiple congenital anomalies-hypotonia-seizures syndrome that is characterized by neonatal hypotonia, lack of psychomotor development, seizures, dysmorphic features, and variable congenital anomalies involving the cardiac, urinary, and gastrointestinal systems and has_material_basis_in homozygous mutation in the PIGN gene on chromosome 18q21.", "url": "https://disease-ontology.org/term/DOID:0080138", "evidence": [ { "id": "0080138", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080138" } ], "weight": 0.0 }, { "disease_id": "DOID:4621", "name": "holoprosencephaly", "description": "A congenital nervous system abnormality characterized by failed or incomplete separation of the forebrain early in gestation; it is accompanied by a spectrum of characteristic craniofacial anomalies.", "url": "https://disease-ontology.org/term/DOID:4621", "evidence": [ { "id": "4621", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4621" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mannose-ethanolamine phosphotransferase activity", "id": "GO:0051377", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051377", "evidence": [ { "database": "UniProtKB", "id": "Q9VB32", "url": "https://www.uniprot.org/uniprotkb/Q9VB32" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VB32", "url": "https://www.uniprot.org/uniprotkb/Q9VB32" } ], "pmid": "" } ], "biological_process": [ { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "Q9VB32", "url": "https://www.uniprot.org/uniprotkb/Q9VB32" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VB32-1" }, { "uniprot_canonical_ac": "Q9VBE8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBE8", "url": "https://www.uniprot.org/uniprotkb/Q9VBE8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 121, "chemical_mass": 13462.0, "gene_names": "Dmel\\CG14237;CG14237;Dmel\\CG14237;Dmel_CG14237", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VBE8-1" }, { "uniprot_canonical_ac": "Q9VBK7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBK7", "url": "https://www.uniprot.org/uniprotkb/Q9VBK7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 677, "chemical_mass": 77620.0, "gene_names": "Mco3;CG5959;Dmel\\CG5959;Dmel_CG5959;MCO3;MIP26036;Mco3;dMCO3", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VBK7", "url": "https://www.uniprot.org/uniprotkb/Q9VBK7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VBK7", "url": "https://www.uniprot.org/uniprotkb/Q9VBK7" } ], "pmid": "" } ], "molecular_function": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "Q9VBK7", "url": "https://www.uniprot.org/uniprotkb/Q9VBK7" } ], "pmid": "" }, { "name": "copper ion binding", "id": "GO:0005507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005507", "evidence": [ { "database": "UniProtKB", "id": "Q9VBK7", "url": "https://www.uniprot.org/uniprotkb/Q9VBK7" } ], "pmid": "" }, { "name": "ferroxidase activity", "id": "GO:0004322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004322", "evidence": [ { "database": "UniProtKB", "id": "Q9VBK7", "url": "https://www.uniprot.org/uniprotkb/Q9VBK7" } ], "pmid": "" } ], "biological_process": [ { "name": "copper ion homeostasis", "id": "GO:0055070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055070", "evidence": [ { "database": "UniProtKB", "id": "Q9VBK7", "url": "https://www.uniprot.org/uniprotkb/Q9VBK7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VBK7-1", "start_pos": "318", "end_pos": "318", "site_lbl": "Thr318", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 318, "start_aa": "Thr", "end_pos": 318, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr318", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VBK7-1" }, { "uniprot_canonical_ac": "Q9VBQ2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBQ2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 432, "chemical_mass": 49220.0, "gene_names": "Dmel\\CG4582;CG4582;Dmel\\CG4582;Dmel_CG4582", "protein_name": "Lipase domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VBQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBQ2" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipase activity", "id": "GO:0016298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016298", "evidence": [ { "database": "UniProtKB", "id": "Q9VBQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBQ2" } ], "pmid": "" }, { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "Q9VBQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBQ2" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "Q9VBQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBQ2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VBQ2-1" }, { "uniprot_canonical_ac": "Q9VBS5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBS5", "url": "https://www.uniprot.org/uniprotkb/Q9VBS5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 415, "chemical_mass": 48044.0, "gene_names": "Dmel\\CG10559;CG10559;Dmel\\CG10559;Dmel_CG10559;Dro16-0", "protein_name": "CHK kinase-like domain-containing protein", "disease": [], "molecular_function": [ { "name": "ecdysteroid 22-kinase activity", "id": "GO:0106389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106389", "evidence": [ { "database": "UniProtKB", "id": "Q9VBS5", "url": "https://www.uniprot.org/uniprotkb/Q9VBS5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VBS5-1" }, { "uniprot_canonical_ac": "Q9VBV9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBV9", "url": "https://www.uniprot.org/uniprotkb/Q9VBV9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 506, "chemical_mass": 55425.0, "gene_names": "Dmel\\CG31103;CG13655;CG31103;Dmel\\CG31103;Dmel_CG31103", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VBV9", "url": "https://www.uniprot.org/uniprotkb/Q9VBV9" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "Q9VBV9", "url": "https://www.uniprot.org/uniprotkb/Q9VBV9" } ], "pmid": "" } ], "biological_process": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "Q9VBV9", "url": "https://www.uniprot.org/uniprotkb/Q9VBV9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VBV9-1" }, { "uniprot_canonical_ac": "Q9VBW4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBW4", "url": "https://www.uniprot.org/uniprotkb/Q9VBW4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 235, "chemical_mass": 27051.0, "gene_names": "Dmel\\CG13653;CG13653;Dmel\\CG13653;Dmel_CG13653", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VBW4-1" }, { "uniprot_canonical_ac": "Q9VBX3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBX3", "url": "https://www.uniprot.org/uniprotkb/Q9VBX3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 443, "chemical_mass": 48705.0, "gene_names": "vig2;BcDNA:SD06613;CG11844;Dmel\\CG11844;Dmel_CG11844;Hero45;Vig2;anon-WO0118547.290;vig-2;vig2", "protein_name": "", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9VBX3", "url": "https://www.uniprot.org/uniprotkb/Q9VBX3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VBX3", "url": "https://www.uniprot.org/uniprotkb/Q9VBX3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VBX3", "url": "https://www.uniprot.org/uniprotkb/Q9VBX3" } ], "pmid": "" }, { "name": "polytene chromosome", "id": "GO:0005700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005700", "evidence": [ { "database": "UniProtKB", "id": "Q9VBX3", "url": "https://www.uniprot.org/uniprotkb/Q9VBX3" } ], "pmid": "" }, { "name": "polytene chromosome chromocenter", "id": "GO:0005701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005701", "evidence": [ { "database": "UniProtKB", "id": "Q9VBX3", "url": "https://www.uniprot.org/uniprotkb/Q9VBX3" } ], "pmid": "" }, { "name": "polytene chromosome puff", "id": "GO:0005703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005703", "evidence": [ { "database": "UniProtKB", "id": "Q9VBX3", "url": "https://www.uniprot.org/uniprotkb/Q9VBX3" } ], "pmid": "" } ], "biological_process": [ { "name": "heterochromatin organization", "id": "GO:0070828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070828", "evidence": [ { "database": "UniProtKB", "id": "Q9VBX3", "url": "https://www.uniprot.org/uniprotkb/Q9VBX3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VBX3-1" }, { "uniprot_canonical_ac": "Q9VBZ2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBZ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBZ2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 222, "chemical_mass": 24565.0, "gene_names": "Dmel\\CG11786;CG11786;Dmel\\CG11786;Dmel_CG11786", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VBZ2-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Thr58", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 58, "start_aa": "Thr", "end_pos": 58, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr58", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VBZ2-1" }, { "uniprot_canonical_ac": "Q9VC32-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VC32", "url": "https://www.uniprot.org/uniprotkb/Q9VC32" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 841, "chemical_mass": 91815.0, "gene_names": "niki;CG10951;Dmel\\CG10951;Dmel_CG10951;NEK1;Niki;niki", "protein_name": "", "disease": [ { "disease_id": "DOID:0060259", "name": "renal-hepatic-pancreatic dysplasia", "description": "A physical disorder characterized by pancreatic fibrosis, renal dysplasia and hepatic dysgenesis; it is usual fatal soon after birth.", "url": "https://disease-ontology.org/term/DOID:0060259", "evidence": [ { "id": "0060259", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060259" } ], "weight": 0.0 }, { "disease_id": "DOID:0060558", "name": "lethal congenital contracture syndrome", "description": "A syndrome characterized by congenital nonprogressive joint contractures. The contractures can involve the upper or lower limbs and/or the vertebral column, leading to various degrees of flexion or extension limitations evident at birth.", "url": "https://disease-ontology.org/term/DOID:0060558", "evidence": [ { "id": "0060558", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060558" } ], "weight": 0.0 }, { "disease_id": "DOID:0081378", "name": "amyotrophic lateral sclerosis type 24", "description": "An amyotrophic lateral sclerosis that is characterized by adult-onset loss of motor neurons and that has_material_basis_in heterozygous mutation in the NEK1 gene on chromosome 4q33.", "url": "https://disease-ontology.org/term/DOID:0081378", "evidence": [ { "id": "0081378", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081378" } ], "weight": 0.0 }, { "disease_id": "DOID:0110861", "name": "autosomal recessive polycystic kidney disease", "description": "A polycystic kidney disease characterized by the presence of multiple cysts located_in the kidney resulting from ciliopathy that disrupts the function of primary cilium, inherited in an autosomal recessive fashion.", "url": "https://disease-ontology.org/term/DOID:0110861", "evidence": [ { "id": "0110861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110861" } ], "weight": 0.0 }, { "disease_id": "DOID:0111120", "name": "nephronophthisis 9", "description": "A nephronophthisis that has_material_basis_in homozygous mutation in the NEK8 gene on chromosome 17q11.", "url": "https://disease-ontology.org/term/DOID:0111120", "evidence": [ { "id": "0111120", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111120" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "Q9VC32", "url": "https://www.uniprot.org/uniprotkb/Q9VC32" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VC32", "url": "https://www.uniprot.org/uniprotkb/Q9VC32" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VC32", "url": "https://www.uniprot.org/uniprotkb/Q9VC32" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VC32", "url": "https://www.uniprot.org/uniprotkb/Q9VC32" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "Q9VC32", "url": "https://www.uniprot.org/uniprotkb/Q9VC32" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VC32-1" }, { "uniprot_canonical_ac": "Q9VC68-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VC68", "url": "https://www.uniprot.org/uniprotkb/Q9VC68" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 280, "chemical_mass": 32025.0, "gene_names": "Dmel\\CG13622;CG13622;Dmel\\CG13622;Dmel_CG13622", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VC68-1" }, { "uniprot_canonical_ac": "Q9VCC4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCC4", "url": "https://www.uniprot.org/uniprotkb/Q9VCC4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 306, "chemical_mass": 36088.0, "gene_names": "TBC1d7;BcDNA:LD17019;CG6182;Dmel\\CG6182;Dmel_CG6182;TBC1D7;TBC1d7;dTBC1D7", "protein_name": "TBC1 domain family member 7", "disease": [], "cellular_component": [ { "name": "TSC1-TSC2 complex", "id": "GO:0033596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033596", "evidence": [ { "database": "UniProtKB", "id": "Q9VCC4", "url": "https://www.uniprot.org/uniprotkb/Q9VCC4" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "Q9VCC4", "url": "https://www.uniprot.org/uniprotkb/Q9VCC4" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "Q9VCC4", "url": "https://www.uniprot.org/uniprotkb/Q9VCC4" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "Q9VCC4", "url": "https://www.uniprot.org/uniprotkb/Q9VCC4" } ], "pmid": "" }, { "name": "TSC1-TSC2 complex binding", "id": "GO:0062078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062078", "evidence": [ { "database": "UniProtKB", "id": "Q9VCC4", "url": "https://www.uniprot.org/uniprotkb/Q9VCC4" } ], "pmid": "" } ], "biological_process": [ { "name": "glucose homeostasis", "id": "GO:0042593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042593", "evidence": [ { "database": "UniProtKB", "id": "Q9VCC4", "url": "https://www.uniprot.org/uniprotkb/Q9VCC4" } ], "pmid": "" }, { "name": "negative regulation of TOR signaling", "id": "GO:0032007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032007", "evidence": [ { "database": "UniProtKB", "id": "Q9VCC4", "url": "https://www.uniprot.org/uniprotkb/Q9VCC4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VCC4-1" }, { "uniprot_canonical_ac": "Q9VCJ2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VCJ2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 311, "chemical_mass": 35796.0, "gene_names": "Dmel\\CG10300;CG10300;Dmel\\CG10300;Dmel_CG10300", "protein_name": "CRAL-TRIO domain-containing protein", "disease": [], "molecular_function": [ { "name": "phosphatidylinositol bisphosphate binding", "id": "GO:1902936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902936", "evidence": [ { "database": "UniProtKB", "id": "Q9VCJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VCJ2" } ], "pmid": "" }, { "name": "lipid transfer activity", "id": "GO:0120013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120013", "evidence": [ { "database": "UniProtKB", "id": "Q9VCJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VCJ2" } ], "pmid": "" } ], "biological_process": [ { "name": "intermembrane lipid transfer", "id": "GO:0120009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120009", "evidence": [ { "database": "UniProtKB", "id": "Q9VCJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VCJ2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VCJ2-1" }, { "uniprot_canonical_ac": "Q9VCJ9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VCJ9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 372, "chemical_mass": 42180.0, "gene_names": "Dmel\\CG16710;CG16710;Dmel\\CG16710;Dmel_CG16710;SP16;cSP16", "protein_name": "CLIP domain-containing serine protease", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "Q9VCJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VCJ9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VCJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VCJ9" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VCJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VCJ9" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VCJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VCJ9" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q9VCJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VCJ9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VCJ9-1" }, { "uniprot_canonical_ac": "Q9VCL3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCL3", "url": "https://www.uniprot.org/uniprotkb/Q9VCL3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 540, "chemical_mass": 62243.0, "gene_names": "Ugt303B2;CG10168;Dmel\\CG10168;Dmel_CG10168;UGT303B2;Ugt303B2", "protein_name": "", "disease": [], "molecular_function": [ { "name": "UDP-glycosyltransferase activity", "id": "GO:0008194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008194", "evidence": [ { "database": "UniProtKB", "id": "Q9VCL3", "url": "https://www.uniprot.org/uniprotkb/Q9VCL3" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VCL3", "url": "https://www.uniprot.org/uniprotkb/Q9VCL3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VCL3-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Thr61", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 61, "start_aa": "Thr", "end_pos": 61, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr61", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VCL3-1" }, { "uniprot_canonical_ac": "Q9VCM8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCM8", "url": "https://www.uniprot.org/uniprotkb/Q9VCM8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 479, "chemical_mass": 54385.0, "gene_names": "Dmel\\CG4408;BEST:GH09055;CG4408;Dmel\\CG4408;Dmel_CG4408", "protein_name": "Zinc carboxypeptidase A 1", "disease": [ { "disease_id": "DOID:0060752", "name": "familial temporal lobe epilepsy 5", "description": "A temporal lobe epilepsy that has_material_basis_in heterozygous mutation in the CPA6 gene on chromosome 8q13.", "url": "https://disease-ontology.org/term/DOID:0060752", "evidence": [ { "id": "0060752", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060752" } ], "weight": 0.0 }, { "disease_id": "DOID:0111308", "name": "familial febrile seizures 11", "description": "A familial febrile seizures that has_material_basis_in homozygous mutation in the CPA6 gene on chromosome 8p13.2.", "url": "https://disease-ontology.org/term/DOID:0111308", "evidence": [ { "id": "0111308", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111308" } ], "weight": 0.0 }, { "disease_id": "DOID:1184", "name": "nephrotic syndrome", "description": "A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.", "url": "https://disease-ontology.org/term/DOID:1184", "evidence": [ { "id": "1184", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1184" } ], "weight": 0.0 }, { "disease_id": "DOID:13241", "name": "Behcet's disease", "description": "An autoimmune disease that is characterized by mucocutaneous manifestations, including recurrent oral and genital ulcerations, ocular manifestations, especially chronic relapsing uveitis, and systemic vasculitis involving arteries and veins of all sizes.", "url": "https://disease-ontology.org/term/DOID:13241", "evidence": [ { "id": "13241", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13241" } ], "weight": 0.0 }, { "disease_id": "DOID:2228", "name": "thrombocytosis", "description": "A blood platelet disease that is characterized by the presence of high platelet counts in the blood.", "url": "https://disease-ontology.org/term/DOID:2228", "evidence": [ { "id": "2228", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2228" } ], "weight": 0.0 }, { "disease_id": "DOID:4989", "name": "pancreatitis", "description": "A pancreas disease that is characterized by inflammation of the pancreas.", "url": "https://disease-ontology.org/term/DOID:4989", "evidence": [ { "id": "4989", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4989" } ], "weight": 0.0 }, { "disease_id": "DOID:784", "name": "chronic kidney disease", "description": "A kidney failure that is characterized by the gradual loss of kidney function, present for a minimum of 3 months. CKD is classified based on cause, glomerular filtration rate (GFR) category (G2-G5), and albuminuria category (A1-A3).", "url": "https://disease-ontology.org/term/DOID:784", "evidence": [ { "id": "784", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:784" } ], "weight": 0.0 }, { "disease_id": "DOID:9351", "name": "diabetes mellitus", "description": "A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.", "url": "https://disease-ontology.org/term/DOID:9351", "evidence": [ { "id": "9351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9351" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VCM8", "url": "https://www.uniprot.org/uniprotkb/Q9VCM8" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VCM8", "url": "https://www.uniprot.org/uniprotkb/Q9VCM8" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VCM8", "url": "https://www.uniprot.org/uniprotkb/Q9VCM8" } ], "pmid": "" }, { "name": "metallocarboxypeptidase activity", "id": "GO:0004181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004181", "evidence": [ { "database": "UniProtKB", "id": "Q9VCM8", "url": "https://www.uniprot.org/uniprotkb/Q9VCM8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VCM8-1", "start_pos": "457", "end_pos": "457", "site_lbl": "Thr457", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 457, "start_aa": "Thr", "end_pos": 457, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr457", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VCM8-1" }, { "uniprot_canonical_ac": "Q9VCN6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCN6", "url": "https://www.uniprot.org/uniprotkb/Q9VCN6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 718, "chemical_mass": 81738.0, "gene_names": "Cdc16;APC6;Apc6;CDC16;CG6759;Cdc16;Dmcdc16;Dmel\\CG6759;Dmel_CG6759;cdc16", "protein_name": "", "disease": [], "biological_process": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "Q9VCN6", "url": "https://www.uniprot.org/uniprotkb/Q9VCN6" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q9VCN6", "url": "https://www.uniprot.org/uniprotkb/Q9VCN6" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "Q9VCN6", "url": "https://www.uniprot.org/uniprotkb/Q9VCN6" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "Q9VCN6", "url": "https://www.uniprot.org/uniprotkb/Q9VCN6" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q9VCN6", "url": "https://www.uniprot.org/uniprotkb/Q9VCN6" } ], "pmid": "" }, { "name": "anaphase-promoting complex-dependent catabolic process", "id": "GO:0031145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031145", "evidence": [ { "database": "UniProtKB", "id": "Q9VCN6", "url": "https://www.uniprot.org/uniprotkb/Q9VCN6" } ], "pmid": "" }, { "name": "positive regulation of mitotic metaphase/anaphase transition", "id": "GO:0045842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045842", "evidence": [ { "database": "UniProtKB", "id": "Q9VCN6", "url": "https://www.uniprot.org/uniprotkb/Q9VCN6" } ], "pmid": "" }, { "name": "regulation of mitotic metaphase/anaphase transition", "id": "GO:0030071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030071", "evidence": [ { "database": "UniProtKB", "id": "Q9VCN6", "url": "https://www.uniprot.org/uniprotkb/Q9VCN6" } ], "pmid": "" }, { "name": "protein catabolic process", "id": "GO:0030163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030163", "evidence": [ { "database": "UniProtKB", "id": "Q9VCN6", "url": "https://www.uniprot.org/uniprotkb/Q9VCN6" } ], "pmid": "" }, { "name": "compound eye photoreceptor cell differentiation", "id": "GO:0001751", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001751", "evidence": [ { "database": "UniProtKB", "id": "Q9VCN6", "url": "https://www.uniprot.org/uniprotkb/Q9VCN6" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VCN6", "url": "https://www.uniprot.org/uniprotkb/Q9VCN6" } ], "pmid": "" }, { "name": "anaphase-promoting complex", "id": "GO:0005680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005680", "evidence": [ { "database": "UniProtKB", "id": "Q9VCN6", "url": "https://www.uniprot.org/uniprotkb/Q9VCN6" } ], "pmid": "" } ], "molecular_function": [ { "name": "enzyme-substrate adaptor activity", "id": "GO:0140767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140767", "evidence": [ { "database": "UniProtKB", "id": "Q9VCN6", "url": "https://www.uniprot.org/uniprotkb/Q9VCN6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VCN6-1" }, { "uniprot_canonical_ac": "Q9VCQ2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VCQ2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 211, "chemical_mass": 23509.0, "gene_names": "Dmel\\CG13829;CG13829;Dmel\\CG13829;Dmel_CG13829", "protein_name": "", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VCQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VCQ2" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "Q9VCQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VCQ2" } ], "pmid": "" } ], "biological_process": [ { "name": "vacuolar proton-transporting V-type ATPase complex assembly", "id": "GO:0070072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070072", "evidence": [ { "database": "UniProtKB", "id": "Q9VCQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VCQ2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VCQ2-1" }, { "uniprot_canonical_ac": "Q9VCT6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCT6", "url": "https://www.uniprot.org/uniprotkb/Q9VCT6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 466, "chemical_mass": 53239.0, "gene_names": "Dmel\\CG13840;CG13840;Dmel\\CG13840;Dmel_CG13840", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VCT6-1" }, { "uniprot_canonical_ac": "Q9VCV8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCV8", "url": "https://www.uniprot.org/uniprotkb/Q9VCV8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 772, "chemical_mass": 89202.0, "gene_names": "Dmel\\CG13842;CG13842;Dmel\\CG13842;Dmel_CG13842", "protein_name": "Coiled-coil protein 142 C-terminal domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VCV8-1" }, { "uniprot_canonical_ac": "Q9VCW2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCW2", "url": "https://www.uniprot.org/uniprotkb/Q9VCW2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 830, "chemical_mass": 92829.0, "gene_names": "cd;CG6969;Dmel\\CG6969;Dmel_CG6969;HPX6;PHS;cd", "protein_name": "", "disease": [ { "disease_id": "DOID:0050328", "name": "congenital hypothyroidism", "description": "A hypothyroidism that is present at birth.", "url": "https://disease-ontology.org/term/DOID:0050328", "evidence": [ { "id": "0050328", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050328" } ], "weight": 0.0 }, { "disease_id": "DOID:0080162", "name": "lupus nephritis", "description": "A glomerulonephritis that is characterized by inflammation of the kidneys resulting from systemic lupus erythematosus.", "url": "https://disease-ontology.org/term/DOID:0080162", "evidence": [ { "id": "0080162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080162" } ], "weight": 0.0 }, { "disease_id": "DOID:0080348", "name": "Alzheimer's disease 1", "description": "An Alzheimer's disease that has_material_basis_in mutation heterozygous mutation in the APP gene, which encodes the amyloid precursor protein, on chromosome 21q21.", "url": "https://disease-ontology.org/term/DOID:0080348", "evidence": [ { "id": "0080348", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080348" } ], "weight": 0.0 }, { "disease_id": "DOID:0112186", "name": "thyroid dyshormonogenesis 2A", "description": "A familial thyroid dyshormonogenesis that has_material_basis_in homozygous or compound heterozygous mutation in TPO on chromosome 2p25.3.", "url": "https://disease-ontology.org/term/DOID:0112186", "evidence": [ { "id": "0112186", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112186" } ], "weight": 0.0 }, { "disease_id": "DOID:1287", "name": "cardiovascular system disease", "description": "A disease of anatomical entity which occurs in the blood, heart, blood vessels or the lymphatic system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells or lymph to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis.", "url": "https://disease-ontology.org/term/DOID:1287", "evidence": [ { "id": "1287", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1287" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:1485", "name": "cystic fibrosis", "description": "A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs.", "url": "https://disease-ontology.org/term/DOID:1485", "evidence": [ { "id": "1485", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1485" } ], "weight": 0.0 }, { "disease_id": "DOID:1591", "name": "renovascular hypertension", "description": "", "url": "https://disease-ontology.org/term/DOID:1591", "evidence": [ { "id": "1591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1591" } ], "weight": 0.0 }, { "disease_id": "DOID:161", "name": "keratosis", "description": "A skin disease characterized_by growth of keratin on the skin or mucous membranes.", "url": "https://disease-ontology.org/term/DOID:161", "evidence": [ { "id": "161", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:161" } ], "weight": 0.0 }, { "disease_id": "DOID:1679", "name": "cystitis", "description": "A bladder disease that is characterized by inflammation of the bladder.", "url": "https://disease-ontology.org/term/DOID:1679", "evidence": [ { "id": "1679", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1679" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:2921", "name": "glomerulonephritis", "description": "A nephritis that causes inflammation of the glomeruli located_in kidney.", "url": "https://disease-ontology.org/term/DOID:2921", "evidence": [ { "id": "2921", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2921" } ], "weight": 0.0 }, { "disease_id": "DOID:3021", "name": "acute kidney failure", "description": "", "url": "https://disease-ontology.org/term/DOID:3021", "evidence": [ { "id": "3021", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3021" } ], "weight": 0.0 }, { "disease_id": "DOID:3082", "name": "interstitial lung disease", "description": "A lung disease that is characterized by inflammation and altered lung interstitium compromising pulmonary function and often has_symptom shortness of breath, dyspnea, and/or cough.", "url": "https://disease-ontology.org/term/DOID:3082", "evidence": [ { "id": "3082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3082" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:5082", "name": "liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:5082", "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 }, { "disease_id": "DOID:850", "name": "lung disease", "description": "A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide.", "url": "https://disease-ontology.org/term/DOID:850", "evidence": [ { "id": "850", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:850" } ], "weight": 0.0 }, { "disease_id": "DOID:865", "name": "vasculitis", "description": "A vascular disease that is characterized by inflammation of the blood vessels.", "url": "https://disease-ontology.org/term/DOID:865", "evidence": [ { "id": "865", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:865" } ], "weight": 0.0 }, { "disease_id": "DOID:874", "name": "bacterial pneumonia", "description": "A pneumonia involving inflammation of the lungs caused by bacteria.", "url": "https://disease-ontology.org/term/DOID:874", "evidence": [ { "id": "874", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:874" } ], "weight": 0.0 }, { "disease_id": "DOID:9362", "name": "status asthmaticus", "description": "An acute asthma that is characterized by an acute episode with a progressive severity that is poorly responsive to standard therapeutic measures, regardless of disease severity or phenotypic variant.", "url": "https://disease-ontology.org/term/DOID:9362", "evidence": [ { "id": "9362", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9362" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VCW2", "url": "https://www.uniprot.org/uniprotkb/Q9VCW2" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "Q9VCW2", "url": "https://www.uniprot.org/uniprotkb/Q9VCW2" } ], "pmid": "" }, { "name": "pigment granule", "id": "GO:0048770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048770", "evidence": [ { "database": "UniProtKB", "id": "Q9VCW2", "url": "https://www.uniprot.org/uniprotkb/Q9VCW2" } ], "pmid": "" } ], "biological_process": [ { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "Q9VCW2", "url": "https://www.uniprot.org/uniprotkb/Q9VCW2" } ], "pmid": "" }, { "name": "kynurenine metabolic process", "id": "GO:0070189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070189", "evidence": [ { "database": "UniProtKB", "id": "Q9VCW2", "url": "https://www.uniprot.org/uniprotkb/Q9VCW2" } ], "pmid": "" }, { "name": "cellular process involved in reproduction in multicellular organism", "id": "GO:0022412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022412", "evidence": [ { "database": "UniProtKB", "id": "Q9VCW2", "url": "https://www.uniprot.org/uniprotkb/Q9VCW2" } ], "pmid": "" }, { "name": "ommochrome biosynthetic process", "id": "GO:0006727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006727", "evidence": [ { "database": "UniProtKB", "id": "Q9VCW2", "url": "https://www.uniprot.org/uniprotkb/Q9VCW2" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VCW2", "url": "https://www.uniprot.org/uniprotkb/Q9VCW2" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9VCW2", "url": "https://www.uniprot.org/uniprotkb/Q9VCW2" } ], "pmid": "" }, { "name": "peroxidase activity", "id": "GO:0004601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004601", "evidence": [ { "database": "UniProtKB", "id": "Q9VCW2", "url": "https://www.uniprot.org/uniprotkb/Q9VCW2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VCW2-1" }, { "uniprot_canonical_ac": "Q9VD47-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VD47", "url": "https://www.uniprot.org/uniprotkb/Q9VD47" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 444, "chemical_mass": 49232.0, "gene_names": "Dmel\\CG13407;CG13407;Dmel\\CG13407;Dmel_CG13407", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VD47-1" }, { "uniprot_canonical_ac": "Q9VD62-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VD62", "url": "https://www.uniprot.org/uniprotkb/Q9VD62" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 562, "chemical_mass": 64813.0, "gene_names": "Qsox3;CG6690;Dmel\\CG6690;Dmel_CG6690;Qsox3", "protein_name": "Sulfhydryl oxidase", "disease": [ { "disease_id": "DOID:14679", "name": "VACTERL association", "description": "A syndrome that is characterized by the presence of at least three of the following: vertebral defects, anal atresia, cardiac defects, tracheo-esophageal fistula, renal anomalies, and limb abnormalities.", "url": "https://disease-ontology.org/term/DOID:14679", "evidence": [ { "id": "14679", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14679" } ], "weight": 0.0 } ], "biological_process": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "Q9VD62", "url": "https://www.uniprot.org/uniprotkb/Q9VD62" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "Q9VD62", "url": "https://www.uniprot.org/uniprotkb/Q9VD62" } ], "pmid": "" }, { "name": "mating", "id": "GO:0007618", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007618", "evidence": [ { "database": "UniProtKB", "id": "Q9VD62", "url": "https://www.uniprot.org/uniprotkb/Q9VD62" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q9VD62", "url": "https://www.uniprot.org/uniprotkb/Q9VD62" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VD62", "url": "https://www.uniprot.org/uniprotkb/Q9VD62" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VD62", "url": "https://www.uniprot.org/uniprotkb/Q9VD62" } ], "pmid": "" } ], "molecular_function": [ { "name": "flavin-dependent sulfhydryl oxidase activity", "id": "GO:0016971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016971", "evidence": [ { "database": "UniProtKB", "id": "Q9VD62", "url": "https://www.uniprot.org/uniprotkb/Q9VD62" } ], "pmid": "" }, { "name": "protein disulfide isomerase activity", "id": "GO:0003756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003756", "evidence": [ { "database": "UniProtKB", "id": "Q9VD62", "url": "https://www.uniprot.org/uniprotkb/Q9VD62" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VD62-1" }, { "uniprot_canonical_ac": "Q9VD91-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VD91", "url": "https://www.uniprot.org/uniprotkb/Q9VD91" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 260, "chemical_mass": 29788.0, "gene_names": "Jhbp16;CG15497;Dmel\\CG15497;Dmel_CG15497;JHBP16;Jhbp16", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VD91", "url": "https://www.uniprot.org/uniprotkb/Q9VD91" } ], "pmid": "" } ], "biological_process": [ { "name": "circadian rhythm", "id": "GO:0007623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007623", "evidence": [ { "database": "UniProtKB", "id": "Q9VD91", "url": "https://www.uniprot.org/uniprotkb/Q9VD91" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VD91-1" }, { "uniprot_canonical_ac": "Q9VDA3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDA3", "url": "https://www.uniprot.org/uniprotkb/Q9VDA3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 200, "chemical_mass": 22517.0, "gene_names": "CheB93a;CG15503;CheB93a;Dmel\\CG15503;Dmel_CG15503", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VDA3", "url": "https://www.uniprot.org/uniprotkb/Q9VDA3" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VDA3", "url": "https://www.uniprot.org/uniprotkb/Q9VDA3" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "Q9VDA3", "url": "https://www.uniprot.org/uniprotkb/Q9VDA3" } ], "pmid": "" } ], "biological_process": [ { "name": "sensory perception of chemical stimulus", "id": "GO:0007606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007606", "evidence": [ { "database": "UniProtKB", "id": "Q9VDA3", "url": "https://www.uniprot.org/uniprotkb/Q9VDA3" } ], "pmid": "" }, { "name": "detection of pheromone", "id": "GO:0043695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043695", "evidence": [ { "database": "UniProtKB", "id": "Q9VDA3", "url": "https://www.uniprot.org/uniprotkb/Q9VDA3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VDA3-1" }, { "uniprot_canonical_ac": "Q9VDA5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDA5", "url": "https://www.uniprot.org/uniprotkb/Q9VDA5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 526, "chemical_mass": 59654.0, "gene_names": "Ugt49B2;CG6475;Dmel\\CG6475;Dmel_CG6475;UGT49B2;Ugt49B2", "protein_name": "UDP-glucuronosyltransferase", "disease": [ { "disease_id": "DOID:10211", "name": "cholelithiasis", "description": "", "url": "https://disease-ontology.org/term/DOID:10211", "evidence": [ { "id": "10211", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10211" } ], "weight": 0.0 }, { "disease_id": "DOID:11151", "name": "cholecystolithiasis", "description": "", "url": "https://disease-ontology.org/term/DOID:11151", "evidence": [ { "id": "11151", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11151" } ], "weight": 0.0 }, { "disease_id": "DOID:1380", "name": "endometrial cancer", "description": "A uterine cancer that is located_in tissues lining the uterus.", "url": "https://disease-ontology.org/term/DOID:1380", "evidence": [ { "id": "1380", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1380" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:2043", "name": "hepatitis B", "description": "A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in Hepatitis B virus (Orthohepadnavirus hominoidei), which is transmitted_by sexual contact, blood transfusions, or fomites like needles or syringes. The infection has_symptom fever, fatigue, loss of appetite, nausea, vomiting, abdominal pain, clay-colored bowel movements, joint pain, and jaundice.", "url": "https://disease-ontology.org/term/DOID:2043", "evidence": [ { "id": "2043", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2043" } ], "weight": 0.0 }, { "disease_id": "DOID:2394", "name": "ovarian cancer", "description": "A female reproductive organ cancer that is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:2394", "evidence": [ { "id": "2394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2394" } ], "weight": 0.0 }, { "disease_id": "DOID:2739", "name": "Gilbert syndrome", "description": "A bilirubin metabolic disorder that involves elevated levels of unconjugated bilirubin as bilirubin is not being conjugated as a result of reduced glucuronyltransferase activity.", "url": "https://disease-ontology.org/term/DOID:2739", "evidence": [ { "id": "2739", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2739" } ], "weight": 0.0 }, { "disease_id": "DOID:2741", "name": "bilirubin metabolic disorder", "description": "An inherited metabolic disorder that involves elevated levels of bilirubin resulting from disruption of bilirubin metabolism.", "url": "https://disease-ontology.org/term/DOID:2741", "evidence": [ { "id": "2741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2741" } ], "weight": 0.0 }, { "disease_id": "DOID:3803", "name": "Crigler-Najjar syndrome", "description": "A bilirubin metabolic disorder that involves a build up of bilirubin as bilirubin is not being broken down as a result of a lack or deficiency of the enzyme uridine diphosphate glycosyltransferase (UGT).", "url": "https://disease-ontology.org/term/DOID:3803", "evidence": [ { "id": "3803", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3803" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:4947", "name": "cholangiocarcinoma", "description": "A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4947", "evidence": [ { "id": "4947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4947" } ], "weight": 0.0 }, { "disease_id": "DOID:4988", "name": "alcoholic pancreatitis", "description": "", "url": "https://disease-ontology.org/term/DOID:4988", "evidence": [ { "id": "4988", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4988" } ], "weight": 0.0 }, { "disease_id": "DOID:7998", "name": "hyperthyroidism", "description": "A thyroid gland disease that involves an over production of thyroid hormone.", "url": "https://disease-ontology.org/term/DOID:7998", "evidence": [ { "id": "7998", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7998" } ], "weight": 0.0 }, { "disease_id": "DOID:8692", "name": "myeloid leukemia", "description": "A leukemia that is located_in myeloid tissue.", "url": "https://disease-ontology.org/term/DOID:8692", "evidence": [ { "id": "8692", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8692" } ], "weight": 0.0 }, { "disease_id": "DOID:8778", "name": "Crohn's disease", "description": "An intestinal disease that involves inflammation located_in intestine.", "url": "https://disease-ontology.org/term/DOID:8778", "evidence": [ { "id": "8778", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8778" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.", "url": "https://disease-ontology.org/term/DOID:9744", "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "UDP-glycosyltransferase activity", "id": "GO:0008194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008194", "evidence": [ { "database": "UniProtKB", "id": "Q9VDA5", "url": "https://www.uniprot.org/uniprotkb/Q9VDA5" } ], "pmid": "" }, { "name": "glucuronosyltransferase activity", "id": "GO:0015020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015020", "evidence": [ { "database": "UniProtKB", "id": "Q9VDA5", "url": "https://www.uniprot.org/uniprotkb/Q9VDA5" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VDA5", "url": "https://www.uniprot.org/uniprotkb/Q9VDA5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VDA5-1" }, { "uniprot_canonical_ac": "Q9VDD4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDD4", "url": "https://www.uniprot.org/uniprotkb/Q9VDD4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 428, "chemical_mass": 48855.0, "gene_names": "Dmel\\CG5810;CG5810;CT18214;Dmel\\CG5810;Dmel_CG5810", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VDD4-1" }, { "uniprot_canonical_ac": "Q9VDF1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDF1", "url": "https://www.uniprot.org/uniprotkb/Q9VDF1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 325, "chemical_mass": 35636.0, "gene_names": "dmrt93B;CG5737;Dmel\\CG5737;Dmel_CG5737;dmrt93B;dmrt93b", "protein_name": "", "disease": [ { "disease_id": "DOID:5426", "name": "primary ovarian insufficiency", "description": "An ovarian disease where ovaries do not produce estrogen despite high levels of circulating gonadotropins in women under 40.", "url": "https://disease-ontology.org/term/DOID:5426", "evidence": [ { "id": "5426", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5426" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VDF1", "url": "https://www.uniprot.org/uniprotkb/Q9VDF1" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q9VDF1", "url": "https://www.uniprot.org/uniprotkb/Q9VDF1" } ], "pmid": "" }, { "name": "sex differentiation", "id": "GO:0007548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007548", "evidence": [ { "database": "UniProtKB", "id": "Q9VDF1", "url": "https://www.uniprot.org/uniprotkb/Q9VDF1" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VDF1", "url": "https://www.uniprot.org/uniprotkb/Q9VDF1" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "Q9VDF1", "url": "https://www.uniprot.org/uniprotkb/Q9VDF1" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q9VDF1", "url": "https://www.uniprot.org/uniprotkb/Q9VDF1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q9VDF1", "url": "https://www.uniprot.org/uniprotkb/Q9VDF1" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "Q9VDF1", "url": "https://www.uniprot.org/uniprotkb/Q9VDF1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VDF1-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Thr32", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 32, "start_aa": "Thr", "end_pos": 32, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr32", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VDF1-1" }, { "uniprot_canonical_ac": "Q9VDN3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDN3", "url": "https://www.uniprot.org/uniprotkb/Q9VDN3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 678, "chemical_mass": 76752.0, "gene_names": "Ir92a;92a;CG15685;DmelIR92a;Dmel\\CG15685;Dmel_CG15685;IR92a;Ir92a", "protein_name": "", "disease": [], "biological_process": [ { "name": "cellular response to ammonium ion", "id": "GO:0071242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071242", "evidence": [ { "database": "UniProtKB", "id": "Q9VDN3", "url": "https://www.uniprot.org/uniprotkb/Q9VDN3" } ], "pmid": "" }, { "name": "positive regulation of calcium-mediated signaling", "id": "GO:0050850", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050850", "evidence": [ { "database": "UniProtKB", "id": "Q9VDN3", "url": "https://www.uniprot.org/uniprotkb/Q9VDN3" } ], "pmid": "" }, { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "Q9VDN3", "url": "https://www.uniprot.org/uniprotkb/Q9VDN3" } ], "pmid": "" }, { "name": "cellular response to amine stimulus", "id": "GO:0071418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071418", "evidence": [ { "database": "UniProtKB", "id": "Q9VDN3", "url": "https://www.uniprot.org/uniprotkb/Q9VDN3" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VDN3", "url": "https://www.uniprot.org/uniprotkb/Q9VDN3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VDN3", "url": "https://www.uniprot.org/uniprotkb/Q9VDN3" } ], "pmid": "" } ], "molecular_function": [ { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "Q9VDN3", "url": "https://www.uniprot.org/uniprotkb/Q9VDN3" } ], "pmid": "" }, { "name": "extracellular ammonia-gated monoatomic ion channel activity", "id": "GO:0036081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036081", "evidence": [ { "database": "UniProtKB", "id": "Q9VDN3", "url": "https://www.uniprot.org/uniprotkb/Q9VDN3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VDN3-1", "start_pos": "161", "end_pos": "161", "site_lbl": "Thr161", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 161, "start_aa": "Thr", "end_pos": 161, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr161", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VDN3-1" }, { "uniprot_canonical_ac": "Q9VDP6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDP6", "url": "https://www.uniprot.org/uniprotkb/Q9VDP6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 461, "chemical_mass": 49823.0, "gene_names": "Dmel\\CG17199;CG17199;Dmel\\CG17199;Dmel_CG17199", "protein_name": "", "disease": [], "molecular_function": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "Q9VDP6", "url": "https://www.uniprot.org/uniprotkb/Q9VDP6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VDP6-1", "start_pos": "159", "end_pos": "159", "site_lbl": "Thr159", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 159, "start_aa": "Thr", "end_pos": 159, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr159", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VDP6-1" }, { "uniprot_canonical_ac": "Q9VDU4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDU4", "url": "https://www.uniprot.org/uniprotkb/Q9VDU4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 537, "chemical_mass": 60202.0, "gene_names": "Acsx1L;Acsx1L;CG6300;Dmel\\CG6300;Dmel_CG6300", "protein_name": "", "disease": [], "biological_process": [ { "name": "long-chain fatty acid metabolic process", "id": "GO:0001676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001676", "evidence": [ { "database": "UniProtKB", "id": "Q9VDU4", "url": "https://www.uniprot.org/uniprotkb/Q9VDU4" } ], "pmid": "" }, { "name": "fatty-acyl-CoA biosynthetic process", "id": "GO:0046949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046949", "evidence": [ { "database": "UniProtKB", "id": "Q9VDU4", "url": "https://www.uniprot.org/uniprotkb/Q9VDU4" } ], "pmid": "" } ], "cellular_component": [ { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "Q9VDU4", "url": "https://www.uniprot.org/uniprotkb/Q9VDU4" } ], "pmid": "" } ], "molecular_function": [ { "name": "long-chain fatty acid-CoA ligase activity", "id": "GO:0004467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004467", "evidence": [ { "database": "UniProtKB", "id": "Q9VDU4", "url": "https://www.uniprot.org/uniprotkb/Q9VDU4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VDU4-1" }, { "uniprot_canonical_ac": "Q9VDY6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDY6", "url": "https://www.uniprot.org/uniprotkb/Q9VDY6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 368, "chemical_mass": 41742.0, "gene_names": "Polr2M;CG3773;Dmel\\CG3773;Dmel_CG3773;Gdn1;Gdown1;Polr2M;anon-EST:fe2D10;anon-EST:fe2D12", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VDY6", "url": "https://www.uniprot.org/uniprotkb/Q9VDY6" } ], "pmid": "" }, { "name": "RNA polymerase II, core complex", "id": "GO:0005665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005665", "evidence": [ { "database": "UniProtKB", "id": "Q9VDY6", "url": "https://www.uniprot.org/uniprotkb/Q9VDY6" } ], "pmid": "" } ], "biological_process": [ { "name": "transcription initiation at RNA polymerase II promoter", "id": "GO:0006367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006367", "evidence": [ { "database": "UniProtKB", "id": "Q9VDY6", "url": "https://www.uniprot.org/uniprotkb/Q9VDY6" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "Q9VDY6", "url": "https://www.uniprot.org/uniprotkb/Q9VDY6" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription elongation factor activity", "id": "GO:0003711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003711", "evidence": [ { "database": "UniProtKB", "id": "Q9VDY6", "url": "https://www.uniprot.org/uniprotkb/Q9VDY6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VDY6-1" }, { "uniprot_canonical_ac": "Q9VDZ7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VDZ7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 459, "chemical_mass": 52875.0, "gene_names": "CG117799;BEST:GM03811;BcDNA:GM03811;CG117799;CG11779;Dmel\\CG11779;Dmel_CG11779;GH-18370", "protein_name": "Mitochondrial import inner membrane translocase subunit TIM44", "disease": [ { "disease_id": "DOID:13207", "name": "proliferative diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:13207", "evidence": [ { "id": "13207", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13207" } ], "weight": 0.0 }, { "disease_id": "DOID:8161", "name": "oncocytic carcinoma of the thyroid", "description": "A thyroid gland follicular carcinoma that is characterized by the presence of large cells with eosinophilic granular cytoplasm and pleomorphic nuclei with prominent, eosinophilic nucleoli.", "url": "https://disease-ontology.org/term/DOID:8161", "evidence": [ { "id": "8161", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8161" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VDZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VDZ7" } ], "pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "Q9VDZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VDZ7" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q9VDZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VDZ7" } ], "pmid": "" }, { "name": "PAM complex, Tim23 associated import motor", "id": "GO:0001405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001405", "evidence": [ { "database": "UniProtKB", "id": "Q9VDZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VDZ7" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to hypoxia", "id": "GO:0071456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071456", "evidence": [ { "database": "UniProtKB", "id": "Q9VDZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VDZ7" } ], "pmid": "" }, { "name": "protein import into mitochondrial matrix", "id": "GO:0030150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030150", "evidence": [ { "database": "UniProtKB", "id": "Q9VDZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VDZ7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VDZ7-1" }, { "uniprot_canonical_ac": "Q9VEH2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VEH2", "url": "https://www.uniprot.org/uniprotkb/Q9VEH2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 260, "chemical_mass": 29157.0, "gene_names": "Dmel\\CG7523;CG7523;Dmel\\CG7523;Dmel_CG7523", "protein_name": "Transmembrane protein 192", "disease": [], "cellular_component": [ { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "Q9VEH2", "url": "https://www.uniprot.org/uniprotkb/Q9VEH2" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "Q9VEH2", "url": "https://www.uniprot.org/uniprotkb/Q9VEH2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VEH2-1" }, { "uniprot_canonical_ac": "Q9VEH5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VEH5", "url": "https://www.uniprot.org/uniprotkb/Q9VEH5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 181, "chemical_mass": 18171.0, "gene_names": "AttD;ATTD;AttD;Attacin D;Att;CG7629;Dmel\\CG7629;Dmel_CG7629;att D;attD;attacin-D;att", "protein_name": "", "disease": [], "biological_process": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q9VEH5", "url": "https://www.uniprot.org/uniprotkb/Q9VEH5" } ], "pmid": "" }, { "name": "defense response to Gram-positive bacterium", "id": "GO:0050830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050830", "evidence": [ { "database": "UniProtKB", "id": "Q9VEH5", "url": "https://www.uniprot.org/uniprotkb/Q9VEH5" } ], "pmid": "" }, { "name": "response to wounding", "id": "GO:0009611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009611", "evidence": [ { "database": "UniProtKB", "id": "Q9VEH5", "url": "https://www.uniprot.org/uniprotkb/Q9VEH5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VEH5-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Thr37", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 37, "start_aa": "Thr", "end_pos": 37, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr37", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VEH5-1" }, { "uniprot_canonical_ac": "Q9VEK5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VEK5", "url": "https://www.uniprot.org/uniprotkb/Q9VEK5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 465, "chemical_mass": 50947.0, "gene_names": "Dmel\\CG17283;CG17283;Dmel\\CG17283;Dmel_CG17283", "protein_name": "Peptidase A1 domain-containing protein", "disease": [], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VEK5", "url": "https://www.uniprot.org/uniprotkb/Q9VEK5" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "Q9VEK5", "url": "https://www.uniprot.org/uniprotkb/Q9VEK5" } ], "pmid": "" } ], "cellular_component": [ { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "Q9VEK5", "url": "https://www.uniprot.org/uniprotkb/Q9VEK5" } ], "pmid": "" } ], "molecular_function": [ { "name": "aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "Q9VEK5", "url": "https://www.uniprot.org/uniprotkb/Q9VEK5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VEK5-1" }, { "uniprot_canonical_ac": "Q9VEL5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VEL5", "url": "https://www.uniprot.org/uniprotkb/Q9VEL5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 225, "chemical_mass": 25026.0, "gene_names": "CG5329;CG31418;CG5329;Dmel\\CG31418;Dmel_CG31418", "protein_name": "", "disease": [], "biological_process": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "Q9VEL5", "url": "https://www.uniprot.org/uniprotkb/Q9VEL5" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VEL5", "url": "https://www.uniprot.org/uniprotkb/Q9VEL5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VEL5-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Thr25", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 25, "start_aa": "Thr", "end_pos": 25, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr25", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VEL5-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Thr29", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 29, "start_aa": "Thr", "end_pos": 29, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr29", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VEL5-1" }, { "uniprot_canonical_ac": "Q9VEM4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VEM4", "url": "https://www.uniprot.org/uniprotkb/Q9VEM4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 643, "chemical_mass": 73515.0, "gene_names": "Dmel\\CG5265;CG5265;CRAT;CrAT;Dmel\\CG5265;Dmel_CG5265", "protein_name": "Choline/carnitine acyltransferase domain-containing protein", "disease": [ { "disease_id": "DOID:0110734", "name": "neurodegeneration with brain iron accumulation", "description": "A neurodegenerative disease characterized by progressive iron accumulation in the basal ganglia and other regions of the brain, resulting in extrapyramidal movements, such as parkinsonism and dystonia.", "url": "https://disease-ontology.org/term/DOID:0110734", "evidence": [ { "id": "0110734", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110734" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VEM4", "url": "https://www.uniprot.org/uniprotkb/Q9VEM4" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "Q9VEM4", "url": "https://www.uniprot.org/uniprotkb/Q9VEM4" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "Q9VEM4", "url": "https://www.uniprot.org/uniprotkb/Q9VEM4" } ], "pmid": "" }, { "name": "fatty acid beta-oxidation using acyl-CoA oxidase", "id": "GO:0033540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033540", "evidence": [ { "database": "UniProtKB", "id": "Q9VEM4", "url": "https://www.uniprot.org/uniprotkb/Q9VEM4" } ], "pmid": "" }, { "name": "carnitine metabolic process, CoA-linked", "id": "GO:0019254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019254", "evidence": [ { "database": "UniProtKB", "id": "Q9VEM4", "url": "https://www.uniprot.org/uniprotkb/Q9VEM4" } ], "pmid": "" } ], "molecular_function": [ { "name": "carnitine O-acetyltransferase activity", "id": "GO:0004092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004092", "evidence": [ { "database": "UniProtKB", "id": "Q9VEM4", "url": "https://www.uniprot.org/uniprotkb/Q9VEM4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VEM4-1" }, { "uniprot_canonical_ac": "Q9VEN2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VEN2", "url": "https://www.uniprot.org/uniprotkb/Q9VEN2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 979, "chemical_mass": 109539.0, "gene_names": "cal1;CAL1;CG5148;CLD2;Cal1;Dmel\\CG5148;Dmel_CG5148;cal1", "protein_name": "", "disease": [], "biological_process": [ { "name": "kinetochore assembly", "id": "GO:0051382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051382", "evidence": [ { "database": "UniProtKB", "id": "Q9VEN2", "url": "https://www.uniprot.org/uniprotkb/Q9VEN2" } ], "pmid": "" }, { "name": "female meiosis chromosome segregation", "id": "GO:0016321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016321", "evidence": [ { "database": "UniProtKB", "id": "Q9VEN2", "url": "https://www.uniprot.org/uniprotkb/Q9VEN2" } ], "pmid": "" }, { "name": "CENP-A containing chromatin assembly", "id": "GO:0034080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034080", "evidence": [ { "database": "UniProtKB", "id": "Q9VEN2", "url": "https://www.uniprot.org/uniprotkb/Q9VEN2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q9VEN2", "url": "https://www.uniprot.org/uniprotkb/Q9VEN2" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "Q9VEN2", "url": "https://www.uniprot.org/uniprotkb/Q9VEN2" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "Q9VEN2", "url": "https://www.uniprot.org/uniprotkb/Q9VEN2" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin-protein adaptor activity", "id": "GO:0140463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140463", "evidence": [ { "database": "UniProtKB", "id": "Q9VEN2", "url": "https://www.uniprot.org/uniprotkb/Q9VEN2" } ], "pmid": "" }, { "name": "histone chaperone activity", "id": "GO:0140713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140713", "evidence": [ { "database": "UniProtKB", "id": "Q9VEN2", "url": "https://www.uniprot.org/uniprotkb/Q9VEN2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VEN2-1", "start_pos": "512", "end_pos": "512", "site_lbl": "Thr512", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 512, "start_aa": "Thr", "end_pos": 512, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr512", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VEN2-1" }, { "uniprot_canonical_ac": "Q9VET3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VET3", "url": "https://www.uniprot.org/uniprotkb/Q9VET3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 119, "chemical_mass": 13471.0, "gene_names": "Dmel\\CG14903;CG14903;Dmel\\CG14903;Dmel_CG14903", "protein_name": "peptidyl-tRNA hydrolase", "disease": [], "molecular_function": [ { "name": "peptidyl-tRNA hydrolase activity", "id": "GO:0004045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004045", "evidence": [ { "database": "UniProtKB", "id": "Q9VET3", "url": "https://www.uniprot.org/uniprotkb/Q9VET3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VET3-1" }, { "uniprot_canonical_ac": "Q9VEV6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VEV6", "url": "https://www.uniprot.org/uniprotkb/Q9VEV6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 286, "chemical_mass": 32540.0, "gene_names": "Dmel\\CG14881;CG14881;Dmel\\CG14881;Dmel_CG14881", "protein_name": "MaoC-like domain-containing protein", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VEV6", "url": "https://www.uniprot.org/uniprotkb/Q9VEV6" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "Q9VEV6", "url": "https://www.uniprot.org/uniprotkb/Q9VEV6" } ], "pmid": "" } ], "molecular_function": [ { "name": "3-hydroxyacyl-CoA dehydratase activity", "id": "GO:0018812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018812", "evidence": [ { "database": "UniProtKB", "id": "Q9VEV6", "url": "https://www.uniprot.org/uniprotkb/Q9VEV6" } ], "pmid": "" }, { "name": "(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity", "id": "GO:0019171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019171", "evidence": [ { "database": "UniProtKB", "id": "Q9VEV6", "url": "https://www.uniprot.org/uniprotkb/Q9VEV6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VEV6-1" }, { "uniprot_canonical_ac": "Q9VFA9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VFA9", "url": "https://www.uniprot.org/uniprotkb/Q9VFA9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 562, "chemical_mass": 60433.0, "gene_names": "Amt;Amt;CG6499;Dmel\\CG6499;Dmel_CG6499", "protein_name": "Ammonium transporter", "disease": [ { "disease_id": "DOID:14219", "name": "renal tubular acidosis", "description": "A renal tubular transport disease characterized by the accumulation of metabolically produced acids with elevated plasma chloride, hyperchloremic metabolic acidosis.", "url": "https://disease-ontology.org/term/DOID:14219", "evidence": [ { "id": "14219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14219" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cellular response to ammonium ion", "id": "GO:0071242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071242", "evidence": [ { "database": "UniProtKB", "id": "Q9VFA9", "url": "https://www.uniprot.org/uniprotkb/Q9VFA9" } ], "pmid": "" }, { "name": "ammonium homeostasis", "id": "GO:0097272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097272", "evidence": [ { "database": "UniProtKB", "id": "Q9VFA9", "url": "https://www.uniprot.org/uniprotkb/Q9VFA9" } ], "pmid": "" }, { "name": "ammonium transmembrane transport", "id": "GO:0072488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072488", "evidence": [ { "database": "UniProtKB", "id": "Q9VFA9", "url": "https://www.uniprot.org/uniprotkb/Q9VFA9" } ], "pmid": "" }, { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "Q9VFA9", "url": "https://www.uniprot.org/uniprotkb/Q9VFA9" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VFA9", "url": "https://www.uniprot.org/uniprotkb/Q9VFA9" } ], "pmid": "" } ], "molecular_function": [ { "name": "ammonium channel activity", "id": "GO:0008519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008519", "evidence": [ { "database": "UniProtKB", "id": "Q9VFA9", "url": "https://www.uniprot.org/uniprotkb/Q9VFA9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VFA9-1" }, { "uniprot_canonical_ac": "Q9VFE1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VFE1", "url": "https://www.uniprot.org/uniprotkb/Q9VFE1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 364, "chemical_mass": 41222.0, "gene_names": "Dmel\\CG14861;CG14861;Dmel\\CG14861;Dmel_CG14861", "protein_name": "EF-hand domain-containing protein", "disease": [], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q9VFE1", "url": "https://www.uniprot.org/uniprotkb/Q9VFE1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VFE1-1" }, { "uniprot_canonical_ac": "Q9VFN1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VFN1", "url": "https://www.uniprot.org/uniprotkb/Q9VFN1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 319, "chemical_mass": 35669.0, "gene_names": "Dmel\\CG14357;CG14357;Dmel\\CG14357;Dmel_CG14357", "protein_name": "C2H2-type domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VFN1-1" }, { "uniprot_canonical_ac": "Q9VFS4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VFS4", "url": "https://www.uniprot.org/uniprotkb/Q9VFS4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 310, "chemical_mass": 35393.0, "gene_names": "Dmel\\CG14367;CG14367;Dmel\\CG14367;Dmel_CG14367", "protein_name": "Cilia- and flagella-associated protein 36", "disease": [], "biological_process": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "Q9VFS4", "url": "https://www.uniprot.org/uniprotkb/Q9VFS4" } ], "pmid": "" } ], "cellular_component": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "Q9VFS4", "url": "https://www.uniprot.org/uniprotkb/Q9VFS4" } ], "pmid": "" }, { "name": "ciliary base", "id": "GO:0097546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097546", "evidence": [ { "database": "UniProtKB", "id": "Q9VFS4", "url": "https://www.uniprot.org/uniprotkb/Q9VFS4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VFS4-1" }, { "uniprot_canonical_ac": "Q9VFU2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VFU2", "url": "https://www.uniprot.org/uniprotkb/Q9VFU2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 112, "chemical_mass": 12160.0, "gene_names": "Dmel\\CG14369;CG14369;Dmel\\CG14369;Dmel_CG14369", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VFU2-1" }, { "uniprot_canonical_ac": "Q9VFU4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VFU4", "url": "https://www.uniprot.org/uniprotkb/Q9VFU4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 194, "chemical_mass": 21192.0, "gene_names": "Dmel\\CG12538;CG12538;Dmel\\CG12538;Dmel_CG12538", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VFU4-1" }, { "uniprot_canonical_ac": "Q9VFW3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VFW3", "url": "https://www.uniprot.org/uniprotkb/Q9VFW3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 183, "chemical_mass": 21453.0, "gene_names": "CheA87a;CG14379;CheA87a;Dmel\\CG14379;Dmel_CG14379", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VFW3", "url": "https://www.uniprot.org/uniprotkb/Q9VFW3" } ], "pmid": "" } ], "biological_process": [ { "name": "sensory perception of chemical stimulus", "id": "GO:0007606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007606", "evidence": [ { "database": "UniProtKB", "id": "Q9VFW3", "url": "https://www.uniprot.org/uniprotkb/Q9VFW3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VFW3-1" }, { "uniprot_canonical_ac": "Q9VFY4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VFY4", "url": "https://www.uniprot.org/uniprotkb/Q9VFY4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 168, "chemical_mass": 19105.0, "gene_names": "Dmel\\CG14380;CG14380;Dmel\\CG14380;Dmel_CG14380", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VFY4-1" }, { "uniprot_canonical_ac": "Q9VG30-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VG30", "url": "https://www.uniprot.org/uniprotkb/Q9VG30" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 530, "chemical_mass": 59128.0, "gene_names": "Ugt37A2;CG5724;Dmel\\CG5724;Dmel_CG5724;UGT37A2;Ugt37A2", "protein_name": "", "disease": [ { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "UDP-glycosyltransferase activity", "id": "GO:0008194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008194", "evidence": [ { "database": "UniProtKB", "id": "Q9VG30", "url": "https://www.uniprot.org/uniprotkb/Q9VG30" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VG30", "url": "https://www.uniprot.org/uniprotkb/Q9VG30" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VG30-1" }, { "uniprot_canonical_ac": "Q9VG47-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VG47", "url": "https://www.uniprot.org/uniprotkb/Q9VG47" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 430, "chemical_mass": 49177.0, "gene_names": "Dmel\\CG11608;CG11608;Dmel\\CG11608;Dmel_CG11608", "protein_name": "Lipase", "disease": [ { "disease_id": "DOID:0080217", "name": "lysosomal acid lipase deficiency", "description": "A lipid storage disease characterized by dyslipidemia and accumulation of cholesteryl esters and triglycerides within various organs that has_material_basis_in homozygous or compound heterozygous mutation in the LIPA gene on chromosome 10q23.31.", "url": "https://disease-ontology.org/term/DOID:0080217", "evidence": [ { "id": "0080217", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080217" } ], "weight": 0.0 }, { "disease_id": "DOID:14497", "name": "Wolman disease", "description": "A lysosomal acid lipase deficiency characterized by infantile onset of rapidly progressive accumulation of cholesteryl esters and triglycerides throughout the body, resulting in hepatosplenomegaly, severe malnutrition, jaundice, vomiting, diarrhea, steatorrhea. Death usually occurs within the first year of life.", "url": "https://disease-ontology.org/term/DOID:14497", "evidence": [ { "id": "14497", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14497" } ], "weight": 0.0 } ], "biological_process": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "Q9VG47", "url": "https://www.uniprot.org/uniprotkb/Q9VG47" } ], "pmid": "" }, { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "Q9VG47", "url": "https://www.uniprot.org/uniprotkb/Q9VG47" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "Q9VG47", "url": "https://www.uniprot.org/uniprotkb/Q9VG47" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VG47", "url": "https://www.uniprot.org/uniprotkb/Q9VG47" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipase activity", "id": "GO:0016298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016298", "evidence": [ { "database": "UniProtKB", "id": "Q9VG47", "url": "https://www.uniprot.org/uniprotkb/Q9VG47" } ], "pmid": "" }, { "name": "serine hydrolase activity", "id": "GO:0017171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017171", "evidence": [ { "database": "UniProtKB", "id": "Q9VG47", "url": "https://www.uniprot.org/uniprotkb/Q9VG47" } ], "pmid": "" }, { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "Q9VG47", "url": "https://www.uniprot.org/uniprotkb/Q9VG47" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VG47-1" }, { "uniprot_canonical_ac": "Q9VG62-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VG62", "url": "https://www.uniprot.org/uniprotkb/Q9VG62" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 485, "chemical_mass": 53165.0, "gene_names": "trus;CG5333;Dmel\\CG5333;Dmel_CG5333;trus", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VG62", "url": "https://www.uniprot.org/uniprotkb/Q9VG62" } ], "pmid": "" } ], "biological_process": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "Q9VG62", "url": "https://www.uniprot.org/uniprotkb/Q9VG62" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VG62-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Thr35", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 35, "start_aa": "Thr", "end_pos": 35, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr35", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VG62-1" }, { "uniprot_canonical_ac": "Q9VG72-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VG72", "url": "https://www.uniprot.org/uniprotkb/Q9VG72" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 501, "chemical_mass": 58790.0, "gene_names": "Dmel\\CG5245;CG5245;Dmel\\CG5245;Dmel_CG5245;anon-WO0118547.611", "protein_name": "Zinc finger protein 865", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "Q9VG72", "url": "https://www.uniprot.org/uniprotkb/Q9VG72" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VG72", "url": "https://www.uniprot.org/uniprotkb/Q9VG72" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q9VG72", "url": "https://www.uniprot.org/uniprotkb/Q9VG72" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VG72", "url": "https://www.uniprot.org/uniprotkb/Q9VG72" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VG72", "url": "https://www.uniprot.org/uniprotkb/Q9VG72" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "Q9VG72", "url": "https://www.uniprot.org/uniprotkb/Q9VG72" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q9VG72", "url": "https://www.uniprot.org/uniprotkb/Q9VG72" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VG72-1" }, { "uniprot_canonical_ac": "Q9VGB6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VGB6", "url": "https://www.uniprot.org/uniprotkb/Q9VGB6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 292, "chemical_mass": 32963.0, "gene_names": "Pgam2;CG17645;Dmel\\CG17645;Dmel_CG17645;Pglym87;Pglym;pglym87", "protein_name": "Phosphoglycerate mutase", "disease": [ { "disease_id": "DOID:0080108", "name": "myoglobinuria", "description": "A myopathy that is characterized by an increased urinary excretion of myoglobin.", "url": "https://disease-ontology.org/term/DOID:0080108", "evidence": [ { "id": "0080108", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080108" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "bisphosphoglycerate mutase activity", "id": "GO:0004082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004082", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB6", "url": "https://www.uniprot.org/uniprotkb/Q9VGB6" } ], "pmid": "" }, { "name": "phosphoglycerate mutase activity", "id": "GO:0004619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004619", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB6", "url": "https://www.uniprot.org/uniprotkb/Q9VGB6" } ], "pmid": "" }, { "name": "phosphatase activity", "id": "GO:0016791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016791", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB6", "url": "https://www.uniprot.org/uniprotkb/Q9VGB6" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB6", "url": "https://www.uniprot.org/uniprotkb/Q9VGB6" } ], "pmid": "" } ], "biological_process": [ { "name": "gluconeogenesis", "id": "GO:0006094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006094", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB6", "url": "https://www.uniprot.org/uniprotkb/Q9VGB6" } ], "pmid": "" }, { "name": "canonical glycolysis", "id": "GO:0061621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061621", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB6", "url": "https://www.uniprot.org/uniprotkb/Q9VGB6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VGB6-1" }, { "uniprot_canonical_ac": "Q9VGB8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VGB8", "url": "https://www.uniprot.org/uniprotkb/Q9VGB8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 267, "chemical_mass": 29147.0, "gene_names": "Dmel\\CG3916;CG3916;Dmel\\CG3916;Dmel_CG3916;SP154", "protein_name": "trypsin", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB8", "url": "https://www.uniprot.org/uniprotkb/Q9VGB8" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB8", "url": "https://www.uniprot.org/uniprotkb/Q9VGB8" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB8", "url": "https://www.uniprot.org/uniprotkb/Q9VGB8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VGB8-1" }, { "uniprot_canonical_ac": "Q9VGQ3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VGQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VGQ3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 264, "chemical_mass": 29513.0, "gene_names": "scpr-A;CG5207;Dmel\\CG5207;Dmel_CG5207;SCPR-A;bs03f04.y1;cg5207;scp-A;scpr-A", "protein_name": "Venom allergen-1", "disease": [], "biological_process": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "Q9VGQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VGQ3" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VGQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VGQ3" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VGQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VGQ3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VGQ3-1" }, { "uniprot_canonical_ac": "Q9VGT4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VGT4", "url": "https://www.uniprot.org/uniprotkb/Q9VGT4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 521, "chemical_mass": 59682.0, "gene_names": "Ugt302E1;AC 006491C;CG4739;Dmel\\CG4739;Dmel_CG4739;UGT302E1;Ugt302E1;Ugt86Dc", "protein_name": "UDP-glucuronosyltransferase", "disease": [], "molecular_function": [ { "name": "UDP-glycosyltransferase activity", "id": "GO:0008194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008194", "evidence": [ { "database": "UniProtKB", "id": "Q9VGT4", "url": "https://www.uniprot.org/uniprotkb/Q9VGT4" } ], "pmid": "" }, { "name": "glucuronosyltransferase activity", "id": "GO:0015020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015020", "evidence": [ { "database": "UniProtKB", "id": "Q9VGT4", "url": "https://www.uniprot.org/uniprotkb/Q9VGT4" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VGT4", "url": "https://www.uniprot.org/uniprotkb/Q9VGT4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VGT4-1" }, { "uniprot_canonical_ac": "Q9VGW4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VGW4", "url": "https://www.uniprot.org/uniprotkb/Q9VGW4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2851, "chemical_mass": 319200.0, "gene_names": "Dmel\\CG14692;CG14692;Dmel\\CG14692;Dmel_CG14692", "protein_name": "RIIa domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VGW4-1", "start_pos": "2238", "end_pos": "2238", "site_lbl": "Thr2238", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2238, "start_aa": "Thr", "end_pos": 2238, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2238", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VGW4-1", "start_pos": "609", "end_pos": "609", "site_lbl": "Thr609", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 609, "start_aa": "Thr", "end_pos": 609, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr609", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VGW4-1" }, { "uniprot_canonical_ac": "Q9VH13-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VH13", "url": "https://www.uniprot.org/uniprotkb/Q9VH13" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 240, "chemical_mass": 25422.0, "gene_names": "Dmel\\CG12420;CG12420;Dmel\\CG12420;Dmel_CG12420", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VH13-1" }, { "uniprot_canonical_ac": "Q9VH59-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VH59", "url": "https://www.uniprot.org/uniprotkb/Q9VH59" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 265, "chemical_mass": 30988.0, "gene_names": "Dmel\\CG8534;CG8534;Dmel\\CG8534;Dmel_CG8534", "protein_name": "Elongation of very long chain fatty acids protein", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VH59", "url": "https://www.uniprot.org/uniprotkb/Q9VH59" } ], "pmid": "" } ], "biological_process": [ { "name": "sphingolipid biosynthetic process", "id": "GO:0030148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030148", "evidence": [ { "database": "UniProtKB", "id": "Q9VH59", "url": "https://www.uniprot.org/uniprotkb/Q9VH59" } ], "pmid": "" }, { "name": "fatty acid elongation", "id": "GO:0030497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030497", "evidence": [ { "database": "UniProtKB", "id": "Q9VH59", "url": "https://www.uniprot.org/uniprotkb/Q9VH59" } ], "pmid": "" }, { "name": "fatty acid elongation, monounsaturated fatty acid", "id": "GO:0034625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034625", "evidence": [ { "database": "UniProtKB", "id": "Q9VH59", "url": "https://www.uniprot.org/uniprotkb/Q9VH59" } ], "pmid": "" }, { "name": "fatty acid elongation, polyunsaturated fatty acid", "id": "GO:0034626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034626", "evidence": [ { "database": "UniProtKB", "id": "Q9VH59", "url": "https://www.uniprot.org/uniprotkb/Q9VH59" } ], "pmid": "" }, { "name": "fatty acid elongation, saturated fatty acid", "id": "GO:0019367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019367", "evidence": [ { "database": "UniProtKB", "id": "Q9VH59", "url": "https://www.uniprot.org/uniprotkb/Q9VH59" } ], "pmid": "" }, { "name": "very long-chain fatty acid biosynthetic process", "id": "GO:0042761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042761", "evidence": [ { "database": "UniProtKB", "id": "Q9VH59", "url": "https://www.uniprot.org/uniprotkb/Q9VH59" } ], "pmid": "" } ], "molecular_function": [ { "name": "fatty acid elongase activity", "id": "GO:0009922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009922", "evidence": [ { "database": "UniProtKB", "id": "Q9VH59", "url": "https://www.uniprot.org/uniprotkb/Q9VH59" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VH59-1" }, { "uniprot_canonical_ac": "Q9VHF6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 520, "chemical_mass": 59764.0, "gene_names": "Aduk;ADUK;Aduk;CG8866;Dmel\\CG8866;Dmel_CG8866;UNC 51-like;dULK3", "protein_name": "Serine/threonine-protein kinase ULK3", "disease": [], "biological_process": [ { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" }, { "name": "regulation of autophagy", "id": "GO:0010506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010506", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" }, { "name": "response to starvation", "id": "GO:0042594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042594", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" }, { "name": "reticulophagy", "id": "GO:0061709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061709", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" }, { "name": "positive regulation of autophagosome assembly", "id": "GO:2000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000786", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" }, { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" }, { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VHF6-1" }, { "uniprot_canonical_ac": "Q9VHG7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VHG7", "url": "https://www.uniprot.org/uniprotkb/Q9VHG7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 277, "chemical_mass": 31807.0, "gene_names": "Dmel\\CG16736;CG16736;Dmel\\CG16736;Dmel_CG16736", "protein_name": "", "disease": [], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG7", "url": "https://www.uniprot.org/uniprotkb/Q9VHG7" } ], "pmid": "" } ], "biological_process": [ { "name": "sulfate transmembrane transport", "id": "GO:1902358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902358", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG7", "url": "https://www.uniprot.org/uniprotkb/Q9VHG7" } ], "pmid": "" }, { "name": "thiosulfate transport", "id": "GO:0015709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015709", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG7", "url": "https://www.uniprot.org/uniprotkb/Q9VHG7" } ], "pmid": "" }, { "name": "oxaloacetate transport", "id": "GO:0015729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015729", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG7", "url": "https://www.uniprot.org/uniprotkb/Q9VHG7" } ], "pmid": "" }, { "name": "phosphate ion transmembrane transport", "id": "GO:0035435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035435", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG7", "url": "https://www.uniprot.org/uniprotkb/Q9VHG7" } ], "pmid": "" }, { "name": "succinate transmembrane transport", "id": "GO:0071422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071422", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG7", "url": "https://www.uniprot.org/uniprotkb/Q9VHG7" } ], "pmid": "" }, { "name": "malate transmembrane transport", "id": "GO:0071423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071423", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG7", "url": "https://www.uniprot.org/uniprotkb/Q9VHG7" } ], "pmid": "" } ], "molecular_function": [ { "name": "sulfate transmembrane transporter activity", "id": "GO:0015116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015116", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG7", "url": "https://www.uniprot.org/uniprotkb/Q9VHG7" } ], "pmid": "" }, { "name": "thiosulfate transmembrane transporter activity", "id": "GO:0015117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015117", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG7", "url": "https://www.uniprot.org/uniprotkb/Q9VHG7" } ], "pmid": "" }, { "name": "oxaloacetate transmembrane transporter activity", "id": "GO:0015131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015131", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG7", "url": "https://www.uniprot.org/uniprotkb/Q9VHG7" } ], "pmid": "" }, { "name": "malate transmembrane transporter activity", "id": "GO:0015140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015140", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG7", "url": "https://www.uniprot.org/uniprotkb/Q9VHG7" } ], "pmid": "" }, { "name": "succinate transmembrane transporter activity", "id": "GO:0015141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015141", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG7", "url": "https://www.uniprot.org/uniprotkb/Q9VHG7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VHG7-1" }, { "uniprot_canonical_ac": "Q9VHG8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VHG8", "url": "https://www.uniprot.org/uniprotkb/Q9VHG8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 443, "chemical_mass": 51012.0, "gene_names": "Dmel\\CG16734;CG16734;Dmel\\CG16734;Dmel_CG16734", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VHG8-1" }, { "uniprot_canonical_ac": "Q9VHM4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VHM4", "url": "https://www.uniprot.org/uniprotkb/Q9VHM4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 346, "chemical_mass": 40730.0, "gene_names": "ranshi;CG9793;Dmel\\CG9793;Dmel_CG9793;ranshi", "protein_name": "", "disease": [], "biological_process": [ { "name": "oocyte differentiation", "id": "GO:0009994", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009994", "evidence": [ { "database": "UniProtKB", "id": "Q9VHM4", "url": "https://www.uniprot.org/uniprotkb/Q9VHM4" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VHM4", "url": "https://www.uniprot.org/uniprotkb/Q9VHM4" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q9VHM4", "url": "https://www.uniprot.org/uniprotkb/Q9VHM4" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q9VHM4", "url": "https://www.uniprot.org/uniprotkb/Q9VHM4" } ], "pmid": "" }, { "name": "germarium-derived oocyte differentiation", "id": "GO:0030706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030706", "evidence": [ { "database": "UniProtKB", "id": "Q9VHM4", "url": "https://www.uniprot.org/uniprotkb/Q9VHM4" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VHM4", "url": "https://www.uniprot.org/uniprotkb/Q9VHM4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q9VHM4", "url": "https://www.uniprot.org/uniprotkb/Q9VHM4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q9VHM4", "url": "https://www.uniprot.org/uniprotkb/Q9VHM4" } ], "pmid": "" } ], "cellular_component": [ { "name": "exon-exon junction complex", "id": "GO:0035145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035145", "evidence": [ { "database": "UniProtKB", "id": "Q9VHM4", "url": "https://www.uniprot.org/uniprotkb/Q9VHM4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VHM4-1" }, { "uniprot_canonical_ac": "Q9VHU7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VHU7", "url": "https://www.uniprot.org/uniprotkb/Q9VHU7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 490, "chemical_mass": 55989.0, "gene_names": "CG7553;CG15864;CG7553;Dmel\\CG15864;Dmel_CG15864", "protein_name": "procollagen-proline 4-dioxygenase", "disease": [], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9VHU7", "url": "https://www.uniprot.org/uniprotkb/Q9VHU7" } ], "pmid": "" }, { "name": "L-ascorbic acid binding", "id": "GO:0031418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031418", "evidence": [ { "database": "UniProtKB", "id": "Q9VHU7", "url": "https://www.uniprot.org/uniprotkb/Q9VHU7" } ], "pmid": "" }, { "name": "procollagen-proline 4-dioxygenase activity", "id": "GO:0004656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004656", "evidence": [ { "database": "UniProtKB", "id": "Q9VHU7", "url": "https://www.uniprot.org/uniprotkb/Q9VHU7" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q9VHU7", "url": "https://www.uniprot.org/uniprotkb/Q9VHU7" } ], "pmid": "" }, { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "Q9VHU7", "url": "https://www.uniprot.org/uniprotkb/Q9VHU7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VHU7-1" }, { "uniprot_canonical_ac": "Q9VHV9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VHV9", "url": "https://www.uniprot.org/uniprotkb/Q9VHV9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 536, "chemical_mass": 58823.0, "gene_names": "Dmel\\CG7900;CG7900;Dmel\\CG7900;Dmel_CG7900", "protein_name": "Amidase domain-containing protein", "disease": [ { "disease_id": "DOID:0060367", "name": "Parkinson's disease 1", "description": "A late onset Parkinson's disease that has_material_basis_in mutation in the alpha-synuclein gene on chromosome 4q22.1.", "url": "https://disease-ontology.org/term/DOID:0060367", "evidence": [ { "id": "0060367", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060367" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:303", "name": "substance-related disorder", "description": "A disease of mental health involving the abuse or dependence on a substance that is ingested in order to produce a high, alter one's senses, or otherwise affect functioning.", "url": "https://disease-ontology.org/term/DOID:303", "evidence": [ { "id": "303", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:303" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 }, { "disease_id": "DOID:9975", "name": "cocaine dependence", "description": "A drug dependence that is a psychological dependency on the regular use of cocaine.", "url": "https://disease-ontology.org/term/DOID:9975", "evidence": [ { "id": "9975", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9975" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "fatty acid amide hydrolase activity", "id": "GO:0017064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017064", "evidence": [ { "database": "UniProtKB", "id": "Q9VHV9", "url": "https://www.uniprot.org/uniprotkb/Q9VHV9" } ], "pmid": "" }, { "name": "monoacylglycerol lipase activity", "id": "GO:0047372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047372", "evidence": [ { "database": "UniProtKB", "id": "Q9VHV9", "url": "https://www.uniprot.org/uniprotkb/Q9VHV9" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid catabolic process", "id": "GO:0009062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009062", "evidence": [ { "database": "UniProtKB", "id": "Q9VHV9", "url": "https://www.uniprot.org/uniprotkb/Q9VHV9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VHV9-1" }, { "uniprot_canonical_ac": "Q9VI35-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VI35", "url": "https://www.uniprot.org/uniprotkb/Q9VI35" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 195, "chemical_mass": 22321.0, "gene_names": "CG2337;CG2337;CG31482;Dmel\\CG31482;Dmel_CG31482", "protein_name": "SCP domain-containing protein", "disease": [ { "disease_id": "DOID:3498", "name": "pancreatic ductal adenocarcinoma", "description": "A pancreatic adenocarcinoma that derives_from pancreatic duct cells.", "url": "https://disease-ontology.org/term/DOID:3498", "evidence": [ { "id": "3498", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3498" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VI35", "url": "https://www.uniprot.org/uniprotkb/Q9VI35" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VI35", "url": "https://www.uniprot.org/uniprotkb/Q9VI35" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VI35-1" }, { "uniprot_canonical_ac": "Q9VI49-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VI49", "url": "https://www.uniprot.org/uniprotkb/Q9VI49" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1047, "chemical_mass": 115206.0, "gene_names": "BcDNA:GH19145;BG:DS00464.1;BcDNA:GH19145;CG1979;Dmel\\CG1979;Dmel_CG1979", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VI49-1" }, { "uniprot_canonical_ac": "Q9VI69-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VI69", "url": "https://www.uniprot.org/uniprotkb/Q9VI69" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 147, "chemical_mass": 17096.0, "gene_names": "Dmel\\CG14610;CG14610;Dmel\\CG14610;Dmel_CG14610", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VI69-1" }, { "uniprot_canonical_ac": "Q9VIG0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VIG0", "url": "https://www.uniprot.org/uniprotkb/Q9VIG0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 347, "chemical_mass": 39253.0, "gene_names": "Dmel\\CG9257;CG9257;Dmel\\CG9257;Dmel_CG9257", "protein_name": "Malectin domain-containing protein", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VIG0", "url": "https://www.uniprot.org/uniprotkb/Q9VIG0" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VIG0", "url": "https://www.uniprot.org/uniprotkb/Q9VIG0" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "Q9VIG0", "url": "https://www.uniprot.org/uniprotkb/Q9VIG0" } ], "pmid": "" } ], "molecular_function": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "Q9VIG0", "url": "https://www.uniprot.org/uniprotkb/Q9VIG0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VIG0-1" }, { "uniprot_canonical_ac": "Q9VIH0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VIH0", "url": "https://www.uniprot.org/uniprotkb/Q9VIH0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 388, "chemical_mass": 43511.0, "gene_names": "Nthl1;9272;CG9272;Dmel\\CG9272;Dmel_CG9272;NTH1;NTHL1;Nth1;Nthl1", "protein_name": "Endonuclease III homolog", "disease": [ { "disease_id": "DOID:0080411", "name": "familial adenomatous polyposis 3", "description": "A familial adenomatous polyposis that has_material_basis_in homozygous or compound heterozygous mutation in the NTHL1 gene on chromosome 16p13.", "url": "https://disease-ontology.org/term/DOID:0080411", "evidence": [ { "id": "0080411", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080411" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q9VIH0", "url": "https://www.uniprot.org/uniprotkb/Q9VIH0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VIH0", "url": "https://www.uniprot.org/uniprotkb/Q9VIH0" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "Q9VIH0", "url": "https://www.uniprot.org/uniprotkb/Q9VIH0" } ], "pmid": "" }, { "name": "DNA-(apurinic or apyrimidinic site) endonuclease activity", "id": "GO:0003906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003906", "evidence": [ { "database": "UniProtKB", "id": "Q9VIH0", "url": "https://www.uniprot.org/uniprotkb/Q9VIH0" } ], "pmid": "" }, { "name": "class I DNA-(apurinic or apyrimidinic site) endonuclease activity", "id": "GO:0140078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140078", "evidence": [ { "database": "UniProtKB", "id": "Q9VIH0", "url": "https://www.uniprot.org/uniprotkb/Q9VIH0" } ], "pmid": "" }, { "name": "oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity", "id": "GO:0000703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000703", "evidence": [ { "database": "UniProtKB", "id": "Q9VIH0", "url": "https://www.uniprot.org/uniprotkb/Q9VIH0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VIH0", "url": "https://www.uniprot.org/uniprotkb/Q9VIH0" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VIH0", "url": "https://www.uniprot.org/uniprotkb/Q9VIH0" } ], "pmid": "" } ], "biological_process": [ { "name": "nucleotide-excision repair", "id": "GO:0006289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006289", "evidence": [ { "database": "UniProtKB", "id": "Q9VIH0", "url": "https://www.uniprot.org/uniprotkb/Q9VIH0" } ], "pmid": "" }, { "name": "base-excision repair, AP site formation", "id": "GO:0006285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006285", "evidence": [ { "database": "UniProtKB", "id": "Q9VIH0", "url": "https://www.uniprot.org/uniprotkb/Q9VIH0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VIH0-1" }, { "uniprot_canonical_ac": "Q9VIK3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VIK3", "url": "https://www.uniprot.org/uniprotkb/Q9VIK3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 448, "chemical_mass": 51013.0, "gene_names": "Dmel\\CG9316;38E.9;CG9316;Dmel\\CG9316;Dmel_CG9316;FBXL10", "protein_name": "F-box domain-containing protein", "disease": [], "cellular_component": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "Q9VIK3", "url": "https://www.uniprot.org/uniprotkb/Q9VIK3" } ], "pmid": "" } ], "biological_process": [ { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "Q9VIK3", "url": "https://www.uniprot.org/uniprotkb/Q9VIK3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VIK3-1" }, { "uniprot_canonical_ac": "Q9VIL6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VIL6", "url": "https://www.uniprot.org/uniprotkb/Q9VIL6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 233, "chemical_mass": 26176.0, "gene_names": "38D.19;38D.19;CG15475;Dmel\\CG15475;Dmel_CG15475", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VIL6-1" }, { "uniprot_canonical_ac": "Q9VJC8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VJC8", "url": "https://www.uniprot.org/uniprotkb/Q9VJC8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 206, "chemical_mass": 22514.0, "gene_names": "Dmel\\CG15142;CG15142;Dmel\\CG15142;Dmel_CG15142", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VJC8", "url": "https://www.uniprot.org/uniprotkb/Q9VJC8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VJC8", "url": "https://www.uniprot.org/uniprotkb/Q9VJC8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VJC8-1" }, { "uniprot_canonical_ac": "Q9VJU2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VJU2", "url": "https://www.uniprot.org/uniprotkb/Q9VJU2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 224, "chemical_mass": 25270.0, "gene_names": "NimC3;BG:DS05899.2;CG16880;Dmel\\CG16880;Dmel_CG16880;I(2)34Fa;NimC3;br30;l(2)34Fa;l(2)br30;l(2)k00811;l34Fa;nimC3", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VJU2", "url": "https://www.uniprot.org/uniprotkb/Q9VJU2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VJU2", "url": "https://www.uniprot.org/uniprotkb/Q9VJU2" } ], "pmid": "" } ], "biological_process": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "Q9VJU2", "url": "https://www.uniprot.org/uniprotkb/Q9VJU2" } ], "pmid": "" }, { "name": "phagocytosis", "id": "GO:0006909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006909", "evidence": [ { "database": "UniProtKB", "id": "Q9VJU2", "url": "https://www.uniprot.org/uniprotkb/Q9VJU2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VJU2-1" }, { "uniprot_canonical_ac": "Q9VJW0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VJW0", "url": "https://www.uniprot.org/uniprotkb/Q9VJW0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 169, "chemical_mass": 19510.0, "gene_names": "Dmel\\CG16888;CG16888;Dmel\\CG16888;Dmel_CG16888", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VJW0-1" }, { "uniprot_canonical_ac": "Q9VK49-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VK49", "url": "https://www.uniprot.org/uniprotkb/Q9VK49" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 282, "chemical_mass": 32180.0, "gene_names": "Dmel\\CG16800;CG16800;Dmel\\CG16800;Dmel_CG16800", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VK49-1" }, { "uniprot_canonical_ac": "Q9VKA3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VKA3", "url": "https://www.uniprot.org/uniprotkb/Q9VKA3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 701, "chemical_mass": 78092.0, "gene_names": "ZnT33D;CG17215;CG31860;Dmel\\CG31860;Dmel_CG31860;ZNT33D;ZnT33D;cg31860;dZnT33D", "protein_name": "", "disease": [ { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 } ], "biological_process": [ { "name": "detoxification of zinc ion", "id": "GO:0010312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010312", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA3", "url": "https://www.uniprot.org/uniprotkb/Q9VKA3" } ], "pmid": "" }, { "name": "zinc ion transmembrane transport", "id": "GO:0071577", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071577", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA3", "url": "https://www.uniprot.org/uniprotkb/Q9VKA3" } ], "pmid": "" }, { "name": "zinc ion transport", "id": "GO:0006829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006829", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA3", "url": "https://www.uniprot.org/uniprotkb/Q9VKA3" } ], "pmid": "" }, { "name": "response to zinc ion", "id": "GO:0010043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010043", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA3", "url": "https://www.uniprot.org/uniprotkb/Q9VKA3" } ], "pmid": "" }, { "name": "intracellular zinc ion homeostasis", "id": "GO:0006882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006882", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA3", "url": "https://www.uniprot.org/uniprotkb/Q9VKA3" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion transmembrane transporter activity", "id": "GO:0005385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005385", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA3", "url": "https://www.uniprot.org/uniprotkb/Q9VKA3" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA3", "url": "https://www.uniprot.org/uniprotkb/Q9VKA3" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA3", "url": "https://www.uniprot.org/uniprotkb/Q9VKA3" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA3", "url": "https://www.uniprot.org/uniprotkb/Q9VKA3" } ], "pmid": "" }, { "name": "transport vesicle membrane", "id": "GO:0030658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030658", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA3", "url": "https://www.uniprot.org/uniprotkb/Q9VKA3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VKA3-1" }, { "uniprot_canonical_ac": "Q9VKE6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VKE6", "url": "https://www.uniprot.org/uniprotkb/Q9VKE6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 584, "chemical_mass": 67250.0, "gene_names": "Mal-B1;CG14934;Dmel\\CG14934;Dmel_CG14934;Drome_B1;Mal-B1;mal_B1", "protein_name": "alpha-glucosidase", "disease": [ { "disease_id": "DOID:9266", "name": "cystinuria", "description": "An amino acid metabolic disorder that involves the formation of cystine stones in the kidneys, ureter, and bladder.", "url": "https://disease-ontology.org/term/DOID:9266", "evidence": [ { "id": "9266", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9266" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "alpha-1,4-glucosidase activity", "id": "GO:0004558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004558", "evidence": [ { "database": "UniProtKB", "id": "Q9VKE6", "url": "https://www.uniprot.org/uniprotkb/Q9VKE6" } ], "pmid": "" } ], "biological_process": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "Q9VKE6", "url": "https://www.uniprot.org/uniprotkb/Q9VKE6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VKE6-1" }, { "uniprot_canonical_ac": "Q9VKH9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VKH9", "url": "https://www.uniprot.org/uniprotkb/Q9VKH9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1931, "chemical_mass": 221829.0, "gene_names": "cana;CENP-E ana;CENPana;CG32955;CG33694;CG4831;CP15516;Cana;Cenp-E;Cenp_E;DmCana;Dmel\\CG33694;Dmel_CG33694;KIF 10;KIF10;cana;l(2)k07716", "protein_name": "", "disease": [ { "disease_id": "DOID:0070283", "name": "primary autosomal recessive microcephaly 13", "description": "A primary autosomal recessive microcephaly that has_material_basis_in homozygous or compound heterozygous mutation in the CENPE gene on chromosome 4q24.", "url": "https://disease-ontology.org/term/DOID:0070283", "evidence": [ { "id": "0070283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070283" } ], "weight": 0.0 } ], "biological_process": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "Q9VKH9", "url": "https://www.uniprot.org/uniprotkb/Q9VKH9" } ], "pmid": "" }, { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "Q9VKH9", "url": "https://www.uniprot.org/uniprotkb/Q9VKH9" } ], "pmid": "" }, { "name": "metaphase/anaphase transition of mitotic cell cycle", "id": "GO:0007091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007091", "evidence": [ { "database": "UniProtKB", "id": "Q9VKH9", "url": "https://www.uniprot.org/uniprotkb/Q9VKH9" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VKH9", "url": "https://www.uniprot.org/uniprotkb/Q9VKH9" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q9VKH9", "url": "https://www.uniprot.org/uniprotkb/Q9VKH9" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "Q9VKH9", "url": "https://www.uniprot.org/uniprotkb/Q9VKH9" } ], "pmid": "" }, { "name": "plus-end-directed microtubule motor activity", "id": "GO:0008574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008574", "evidence": [ { "database": "UniProtKB", "id": "Q9VKH9", "url": "https://www.uniprot.org/uniprotkb/Q9VKH9" } ], "pmid": "" } ], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q9VKH9", "url": "https://www.uniprot.org/uniprotkb/Q9VKH9" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "Q9VKH9", "url": "https://www.uniprot.org/uniprotkb/Q9VKH9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VKH9-1", "start_pos": "1884", "end_pos": "1884", "site_lbl": "Thr1884", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1884, "start_aa": "Thr", "end_pos": 1884, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1884", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VKH9-1" }, { "uniprot_canonical_ac": "Q9VKR1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VKR1", "url": "https://www.uniprot.org/uniprotkb/Q9VKR1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 281, "chemical_mass": 31707.0, "gene_names": "Dmel\\CG17118;CG17118;Dmel\\CG17118;Dmel_CG17118", "protein_name": "CFA20 domain-containing protein", "disease": [], "cellular_component": [ { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "Q9VKR1", "url": "https://www.uniprot.org/uniprotkb/Q9VKR1" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "Q9VKR1", "url": "https://www.uniprot.org/uniprotkb/Q9VKR1" } ], "pmid": "" } ], "biological_process": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "Q9VKR1", "url": "https://www.uniprot.org/uniprotkb/Q9VKR1" } ], "pmid": "" }, { "name": "positive regulation of cell motility", "id": "GO:2000147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000147", "evidence": [ { "database": "UniProtKB", "id": "Q9VKR1", "url": "https://www.uniprot.org/uniprotkb/Q9VKR1" } ], "pmid": "" }, { "name": "regulation of cilium beat frequency involved in ciliary motility", "id": "GO:0060296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060296", "evidence": [ { "database": "UniProtKB", "id": "Q9VKR1", "url": "https://www.uniprot.org/uniprotkb/Q9VKR1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VKR1-1" }, { "uniprot_canonical_ac": "Q9VL26-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VL26", "url": "https://www.uniprot.org/uniprotkb/Q9VL26" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 183, "chemical_mass": 21384.0, "gene_names": "BcDNA:LD02427;BcDNA:LD02427;CG5727;Dmel\\CG5727;Dmel_CG5727", "protein_name": "Myb/SANT-like DNA-binding domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VL26-1" }, { "uniprot_canonical_ac": "Q9VL47-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VL47", "url": "https://www.uniprot.org/uniprotkb/Q9VL47" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 734, "chemical_mass": 84400.0, "gene_names": "Dmel\\CG13127;CG13127;Dmel\\CG13127;Dmel_CG13127", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VL47-1" }, { "uniprot_canonical_ac": "Q9VL77-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VL77", "url": "https://www.uniprot.org/uniprotkb/Q9VL77" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 97, "chemical_mass": 10725.0, "gene_names": "Dmel\\CG4537;CG4537;Dmel\\CG4537;Dmel_CG4537", "protein_name": "Cysteine-rich PDZ-binding protein", "disease": [ { "disease_id": "DOID:2732", "name": "Rothmund-Thomson syndrome", "description": "A skin disease characterized by poikiloderma, congenital bone defects, and an increased risk of osteosarcoma in childhood and skin cancer later in life that has_material_basis_in homozygous or compound heterozygous mutation in the DNA helicase gene RECQL4 on chromosome 8q24.", "url": "https://disease-ontology.org/term/DOID:2732", "evidence": [ { "id": "2732", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2732" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VL77", "url": "https://www.uniprot.org/uniprotkb/Q9VL77" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q9VL77", "url": "https://www.uniprot.org/uniprotkb/Q9VL77" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "Q9VL77", "url": "https://www.uniprot.org/uniprotkb/Q9VL77" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q9VL77", "url": "https://www.uniprot.org/uniprotkb/Q9VL77" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "Q9VL77", "url": "https://www.uniprot.org/uniprotkb/Q9VL77" } ], "pmid": "" }, { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "Q9VL77", "url": "https://www.uniprot.org/uniprotkb/Q9VL77" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q9VL77", "url": "https://www.uniprot.org/uniprotkb/Q9VL77" } ], "pmid": "" }, { "name": "PDZ domain binding", "id": "GO:0030165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030165", "evidence": [ { "database": "UniProtKB", "id": "Q9VL77", "url": "https://www.uniprot.org/uniprotkb/Q9VL77" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VL77-1" }, { "uniprot_canonical_ac": "Q9VLB4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VLB4", "url": "https://www.uniprot.org/uniprotkb/Q9VLB4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 328, "chemical_mass": 32588.0, "gene_names": "CG17022;CG17022;CG31883;Dmel\\CG31883;Dmel_CG31883;anon-WO0140519.218", "protein_name": "", "disease": [], "biological_process": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "Q9VLB4", "url": "https://www.uniprot.org/uniprotkb/Q9VLB4" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VLB4", "url": "https://www.uniprot.org/uniprotkb/Q9VLB4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VLB4-1", "start_pos": "66", "end_pos": "66", "site_lbl": "Thr66", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 66, "start_aa": "Thr", "end_pos": 66, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr66", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VLB4-1", "start_pos": "79", "end_pos": "79", "site_lbl": "Thr79", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 79, "start_aa": "Thr", "end_pos": 79, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr79", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VLB4", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VLB4" } ] } ] } ], "record_id": "Q9VLB4-1" }, { "uniprot_canonical_ac": "Q9VLG0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VLG0", "url": "https://www.uniprot.org/uniprotkb/Q9VLG0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 146, "chemical_mass": 16456.0, "gene_names": "Dmel\\CG18662;CG18662;Dmel\\CG18662;Dmel_CG18662", "protein_name": "Sex-regulated protein janus-B", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VLG0", "url": "https://www.uniprot.org/uniprotkb/Q9VLG0" } ], "pmid": "" } ], "biological_process": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "Q9VLG0", "url": "https://www.uniprot.org/uniprotkb/Q9VLG0" } ], "pmid": "" }, { "name": "sex differentiation", "id": "GO:0007548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007548", "evidence": [ { "database": "UniProtKB", "id": "Q9VLG0", "url": "https://www.uniprot.org/uniprotkb/Q9VLG0" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein histidine phosphatase activity", "id": "GO:0101006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0101006", "evidence": [ { "database": "UniProtKB", "id": "Q9VLG0", "url": "https://www.uniprot.org/uniprotkb/Q9VLG0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VLG0-1" }, { "uniprot_canonical_ac": "Q9VLH6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VLH6", "url": "https://www.uniprot.org/uniprotkb/Q9VLH6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 250, "chemical_mass": 27440.0, "gene_names": "CG18663;CG18663;CG32983;Dmel\\CG32983;Dmel_CG32983", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VLH6-1" }, { "uniprot_canonical_ac": "Q9VLL6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VLL6", "url": "https://www.uniprot.org/uniprotkb/Q9VLL6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 284, "chemical_mass": 29225.0, "gene_names": "Dmel\\CG13386;CG13386;Dmel\\CG13386;Dmel_CG13386", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VLL6-1" }, { "uniprot_canonical_ac": "Q9VLN0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VLN0", "url": "https://www.uniprot.org/uniprotkb/Q9VLN0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 381, "chemical_mass": 41475.0, "gene_names": "Dmel\\CG13390;CG13390;Dmel\\CG13390;Dmel_CG13390", "protein_name": "Mitochondrial ribosome-associated GTPase 2", "disease": [], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "Q9VLN0", "url": "https://www.uniprot.org/uniprotkb/Q9VLN0" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q9VLN0", "url": "https://www.uniprot.org/uniprotkb/Q9VLN0" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q9VLN0", "url": "https://www.uniprot.org/uniprotkb/Q9VLN0" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VLN0", "url": "https://www.uniprot.org/uniprotkb/Q9VLN0" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q9VLN0", "url": "https://www.uniprot.org/uniprotkb/Q9VLN0" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial large ribosomal subunit assembly", "id": "GO:1902775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902775", "evidence": [ { "database": "UniProtKB", "id": "Q9VLN0", "url": "https://www.uniprot.org/uniprotkb/Q9VLN0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VLN0-1" }, { "uniprot_canonical_ac": "Q9VLU9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VLU9", "url": "https://www.uniprot.org/uniprotkb/Q9VLU9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 358, "chemical_mass": 39925.0, "gene_names": "Dmel\\CG7231;CG7231;Dmel\\CG7231;Dmel_CG7231", "protein_name": "Menorin-like domain-containing protein", "disease": [ { "disease_id": "DOID:0050861", "name": "colorectal adenocarcinoma", "description": "A colorectal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:0050861", "evidence": [ { "id": "0050861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050861" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VLU9", "url": "https://www.uniprot.org/uniprotkb/Q9VLU9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VLU9-1" }, { "uniprot_canonical_ac": "Q9VM54-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VM54", "url": "https://www.uniprot.org/uniprotkb/Q9VM54" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 359, "chemical_mass": 41461.0, "gene_names": "Dmel\\CG43322;CG13776;CG43322;Dmel\\CG43322;Dmel_CG43322", "protein_name": "J domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VM54-1" }, { "uniprot_canonical_ac": "Q9VME8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VME8", "url": "https://www.uniprot.org/uniprotkb/Q9VME8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 504, "chemical_mass": 58910.0, "gene_names": "ppk14;CG9501;Dmel\\CG9501;Dmel_CG9501;PPK14;Ppk14;ppk14", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VME8", "url": "https://www.uniprot.org/uniprotkb/Q9VME8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VME8", "url": "https://www.uniprot.org/uniprotkb/Q9VME8" } ], "pmid": "" } ], "biological_process": [ { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "Q9VME8", "url": "https://www.uniprot.org/uniprotkb/Q9VME8" } ], "pmid": "" }, { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "Q9VME8", "url": "https://www.uniprot.org/uniprotkb/Q9VME8" } ], "pmid": "" } ], "molecular_function": [ { "name": "sodium channel activity", "id": "GO:0005272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005272", "evidence": [ { "database": "UniProtKB", "id": "Q9VME8", "url": "https://www.uniprot.org/uniprotkb/Q9VME8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VME8-1" }, { "uniprot_canonical_ac": "Q9VMK7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VMK7", "url": "https://www.uniprot.org/uniprotkb/Q9VMK7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 97, "chemical_mass": 11730.0, "gene_names": "Dmel\\CG13998;CG13998;Dmel\\CG13998;Dmel_CG13998", "protein_name": "", "disease": [], "biological_process": [ { "name": "vitelline membrane formation involved in chorion-containing eggshell formation", "id": "GO:0007305", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007305", "evidence": [ { "database": "UniProtKB", "id": "Q9VMK7", "url": "https://www.uniprot.org/uniprotkb/Q9VMK7" } ], "pmid": "" } ], "cellular_component": [ { "name": "egg chorion", "id": "GO:0042600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042600", "evidence": [ { "database": "UniProtKB", "id": "Q9VMK7", "url": "https://www.uniprot.org/uniprotkb/Q9VMK7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VMK7-1" }, { "uniprot_canonical_ac": "Q9VML2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 3489, "chemical_mass": 389825.0, "gene_names": "bchs;Alfy;BcDNA:SD12984;Bchs;Beach1;CG14001;CG9011;DBEACH1;Dmel\\CG14001;Dmel_CG14001;EP2299;alfy;bchd;bchs;beach", "protein_name": "", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0070295", "name": "primary autosomal dominant microcephaly 18", "description": "A primary microcephaly that has_material_basis_in heterozygous mutation in the WDFY3 gene on chromosome 4q21.", "url": "https://disease-ontology.org/term/DOID:0070295", "evidence": [ { "id": "0070295", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070295" } ], "weight": 0.0 }, { "disease_id": "DOID:2935", "name": "Chediak-Higashi syndrome", "description": "A syndrome characterized by oculocutaneous albinism, immune deficiency, coagulation deficiency and neuropathy and that has_material_basis_in homozygous or compound heterozygous mutation in the lysosomal trafficking regulator gene (LYST) on chromosome 1q42.", "url": "https://disease-ontology.org/term/DOID:2935", "evidence": [ { "id": "2935", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2935" } ], "weight": 0.0 } ], "biological_process": [ { "name": "compound eye development", "id": "GO:0048749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048749", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" }, { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" }, { "name": "positive regulation of organ growth", "id": "GO:0046622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046622", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" }, { "name": "neuron development", "id": "GO:0048666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048666", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" }, { "name": "lysosome localization", "id": "GO:0032418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032418", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" }, { "name": "fasciculation of motor neuron axon", "id": "GO:0097156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097156", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" }, { "name": "regulation of synapse organization", "id": "GO:0050807", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050807", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" }, { "name": "microtubule bundle formation", "id": "GO:0001578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001578", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" }, { "name": "regulation of protein ubiquitination", "id": "GO:0031396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031396", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" }, { "name": "chaeta development", "id": "GO:0022416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022416", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" }, { "name": "presynaptic active zone", "id": "GO:0048786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048786", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VML2-1", "start_pos": "2314", "end_pos": "2314", "site_lbl": "Thr2314", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2314, "start_aa": "Thr", "end_pos": 2314, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2314", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VML2-1", "start_pos": "42", "end_pos": "42", "site_lbl": "Thr42", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 42, "start_aa": "Thr", "end_pos": 42, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr42", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VML2-1" }, { "uniprot_canonical_ac": "Q9VMX7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VMX7", "url": "https://www.uniprot.org/uniprotkb/Q9VMX7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 266, "chemical_mass": 28720.0, "gene_names": "Jon25Bi;25B;CG8867;Dmel\\CG8867;Dmel_CG8867;Jon25Bi;Jon25B;Jon25i;Jon25;SP137;Ser4", "protein_name": "", "disease": [], "molecular_function": [ { "name": "endopeptidase activity", "id": "GO:0004175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004175", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX7", "url": "https://www.uniprot.org/uniprotkb/Q9VMX7" } ], "pmid": "" }, { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX7", "url": "https://www.uniprot.org/uniprotkb/Q9VMX7" } ], "pmid": "" }, { "name": "serine hydrolase activity", "id": "GO:0017171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017171", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX7", "url": "https://www.uniprot.org/uniprotkb/Q9VMX7" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX7", "url": "https://www.uniprot.org/uniprotkb/Q9VMX7" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX7", "url": "https://www.uniprot.org/uniprotkb/Q9VMX7" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX7", "url": "https://www.uniprot.org/uniprotkb/Q9VMX7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VMX7-1" }, { "uniprot_canonical_ac": "Q9VN30-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VN30", "url": "https://www.uniprot.org/uniprotkb/Q9VN30" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1079, "chemical_mass": 126895.0, "gene_names": "sac;CG14651;Dmel\\CG14651;Dmel_CG14651;sac", "protein_name": "", "disease": [], "biological_process": [ { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "Q9VN30", "url": "https://www.uniprot.org/uniprotkb/Q9VN30" } ], "pmid": "" } ], "cellular_component": [ { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "Q9VN30", "url": "https://www.uniprot.org/uniprotkb/Q9VN30" } ], "pmid": "" }, { "name": "dynein complex", "id": "GO:0030286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030286", "evidence": [ { "database": "UniProtKB", "id": "Q9VN30", "url": "https://www.uniprot.org/uniprotkb/Q9VN30" } ], "pmid": "" } ], "molecular_function": [ { "name": "dynein light intermediate chain binding", "id": "GO:0051959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051959", "evidence": [ { "database": "UniProtKB", "id": "Q9VN30", "url": "https://www.uniprot.org/uniprotkb/Q9VN30" } ], "pmid": "" }, { "name": "dynein intermediate chain binding", "id": "GO:0045505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045505", "evidence": [ { "database": "UniProtKB", "id": "Q9VN30", "url": "https://www.uniprot.org/uniprotkb/Q9VN30" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VN30-1" }, { "uniprot_canonical_ac": "Q9VN42-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VN42", "url": "https://www.uniprot.org/uniprotkb/Q9VN42" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 226, "chemical_mass": 25971.0, "gene_names": "Dlip2;CG9771;DIP2;Dip2;Dlip2;Dmel\\CG9771;Dmel_CG9771;dip2;dmDIP2;sip4", "protein_name": "", "disease": [], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VN42", "url": "https://www.uniprot.org/uniprotkb/Q9VN42" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "Q9VN42", "url": "https://www.uniprot.org/uniprotkb/Q9VN42" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VN42-1" }, { "uniprot_canonical_ac": "Q9VN65-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VN65", "url": "https://www.uniprot.org/uniprotkb/Q9VN65" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 97, "chemical_mass": 11965.0, "gene_names": "Dmel\\CG14659;CG14659;Dmel\\CG14659;Dmel_CG14659", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VN65-1" }, { "uniprot_canonical_ac": "Q9VNF5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VNF5", "url": "https://www.uniprot.org/uniprotkb/Q9VNF5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 438, "chemical_mass": 46379.0, "gene_names": "anon-WO0118547.367;CG12170;Dmel\\CG12170;Dmel_CG12170;anon-WO0118547.367", "protein_name": "3-oxoacyl-[acyl-carrier-protein] synthase", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VNF5", "url": "https://www.uniprot.org/uniprotkb/Q9VNF5" } ], "pmid": "" } ], "biological_process": [ { "name": "acyl-CoA metabolic process", "id": "GO:0006637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006637", "evidence": [ { "database": "UniProtKB", "id": "Q9VNF5", "url": "https://www.uniprot.org/uniprotkb/Q9VNF5" } ], "pmid": "" }, { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "Q9VNF5", "url": "https://www.uniprot.org/uniprotkb/Q9VNF5" } ], "pmid": "" } ], "molecular_function": [ { "name": "3-oxoacyl-[acyl-carrier-protein] synthase activity", "id": "GO:0004315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004315", "evidence": [ { "database": "UniProtKB", "id": "Q9VNF5", "url": "https://www.uniprot.org/uniprotkb/Q9VNF5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VNF5-1" }, { "uniprot_canonical_ac": "Q9VNN0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VNN0", "url": "https://www.uniprot.org/uniprotkb/Q9VNN0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 351, "chemical_mass": 38478.0, "gene_names": "Osi10a;10a_CG15593;CG15593;CG46436;Dmel\\CG46436;Dmel_CG46436;Osi10a;Osi10", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VNN0", "url": "https://www.uniprot.org/uniprotkb/Q9VNN0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VNN0", "url": "https://www.uniprot.org/uniprotkb/Q9VNN0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VNN0-1", "start_pos": "125", "end_pos": "125", "site_lbl": "Thr125", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 125, "start_aa": "Thr", "end_pos": 125, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr125", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VNN0-1" }, { "uniprot_canonical_ac": "Q9VNU3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VNU3", "url": "https://www.uniprot.org/uniprotkb/Q9VNU3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 538, "chemical_mass": 64375.0, "gene_names": "Dmel\\CG11449;CG11449;Dmel\\CG11449;Dmel_CG11449", "protein_name": "Cilia- and flagella-associated protein 45", "disease": [ { "disease_id": "DOID:0051025", "name": "visceral heterotaxy 11", "description": "A visceral heterotaxy that is characterized by a failure to generate normal left-right visceral asymmetry during embryogenesis, which can result in heterotaxy syndrome or situs inversus totalis and that has_material_basis_in homozygous or compound heterozygous mutation in the CFAP45 gene on chromosome 1q23.", "url": "https://disease-ontology.org/term/DOID:0051025", "evidence": [ { "id": "0051025", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051025" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "Q9VNU3", "url": "https://www.uniprot.org/uniprotkb/Q9VNU3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VNU3-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Thr103", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 103, "start_aa": "Thr", "end_pos": 103, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr103", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VNU3", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VNU3" } ] } ] }, { "uniprot_canonical_ac": "Q9VNU3-1", "start_pos": "105", "end_pos": "105", "site_lbl": "Ser105", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 105, "start_aa": "Ser", "end_pos": 105, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser105", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VNU3", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VNU3" } ] } ] } ], "record_id": "Q9VNU3-1" }, { "uniprot_canonical_ac": "Q9VNY9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VNY9", "url": "https://www.uniprot.org/uniprotkb/Q9VNY9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 192, "chemical_mass": 20819.0, "gene_names": "Dmel\\CG14573;CG14573;Dmel\\CG14573;Dmel_CG14573", "protein_name": "DUF4794 domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VNY9-1" }, { "uniprot_canonical_ac": "Q9VNZ9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VNZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VNZ9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 642, "chemical_mass": 73674.0, "gene_names": "Pykl5;CG11249;Dmel\\CG11249;Dmel_CG11249", "protein_name": "", "disease": [], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "Q9VNZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VNZ9" } ], "pmid": "" }, { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "Q9VNZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VNZ9" } ], "pmid": "" }, { "name": "potassium ion binding", "id": "GO:0030955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030955", "evidence": [ { "database": "UniProtKB", "id": "Q9VNZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VNZ9" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VNZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VNZ9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VNZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VNZ9" } ], "pmid": "" } ], "biological_process": [ { "name": "glycolytic process", "id": "GO:0006096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006096", "evidence": [ { "database": "UniProtKB", "id": "Q9VNZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VNZ9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VNZ9-1" }, { "uniprot_canonical_ac": "Q9VPB4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPB4", "url": "https://www.uniprot.org/uniprotkb/Q9VPB4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 340, "chemical_mass": 38217.0, "gene_names": "Dmel\\CG3698;CG3698;Dmel\\CG3698;Dmel_CG3698", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VPB4-1" }, { "uniprot_canonical_ac": "Q9VPD9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPD9", "url": "https://www.uniprot.org/uniprotkb/Q9VPD9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 504, "chemical_mass": 55360.0, "gene_names": "Dmel\\CG17637;CG17637;Dmel\\CG17637;Dmel_CG17637", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VPD9", "url": "https://www.uniprot.org/uniprotkb/Q9VPD9" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "Q9VPD9", "url": "https://www.uniprot.org/uniprotkb/Q9VPD9" } ], "pmid": "" } ], "biological_process": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "Q9VPD9", "url": "https://www.uniprot.org/uniprotkb/Q9VPD9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VPD9-1" }, { "uniprot_canonical_ac": "A0A0B4K7E5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7E5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7E5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 110, "chemical_mass": 12730.0, "gene_names": "lincRNA.337;CG43272;Dmel\\CG43272;Dmel_CG43272", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4K7E5-1" }, { "uniprot_canonical_ac": "A1ZAQ3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZAQ3", "url": "https://www.uniprot.org/uniprotkb/A1ZAQ3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 682, "chemical_mass": 79724.0, "gene_names": "CG15612;Dmel\\CG46491;CG15612;CG15613;CG30456;CG46491;Dmel\\CG46491;Dmel_CG46491", "protein_name": "DH domain-containing protein", "disease": [ { "disease_id": "DOID:0061036", "name": "autosomal dominant intellectual developmental disorder 63 with macrocephaly", "description": "An autosomal dominant intellectual developmental disorder that has_material_basis_in heterozygous mutation in the TRIO gene on chromosome 5p15.", "url": "https://disease-ontology.org/term/DOID:0061036", "evidence": [ { "id": "0061036", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061036" } ], "weight": 0.0 }, { "disease_id": "DOID:0070074", "name": "autosomal dominant intellectual developmental disorder 44", "description": "An autosomal dominant intellectual developmental disorder that has_material_basis_in an autosomal dominant mutation of the TRIO gene on chromosome 5p15.2.", "url": "https://disease-ontology.org/term/DOID:0070074", "evidence": [ { "id": "0070074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070074" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A1ZAQ3", "url": "https://www.uniprot.org/uniprotkb/A1ZAQ3" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of Rho protein signal transduction", "id": "GO:0035025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035025", "evidence": [ { "database": "UniProtKB", "id": "A1ZAQ3", "url": "https://www.uniprot.org/uniprotkb/A1ZAQ3" } ], "pmid": "" }, { "name": "imaginal disc-derived leg morphogenesis", "id": "GO:0007480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007480", "evidence": [ { "database": "UniProtKB", "id": "A1ZAQ3", "url": "https://www.uniprot.org/uniprotkb/A1ZAQ3" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1ZAQ3", "url": "https://www.uniprot.org/uniprotkb/A1ZAQ3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1ZAQ3-1", "start_pos": "170", "end_pos": "170", "site_lbl": "Thr170", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 170, "start_aa": "Thr", "end_pos": 170, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr170", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A1ZAQ3-1" }, { "uniprot_canonical_ac": "A0A0B4K651-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K651", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K651" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 784, "chemical_mass": 86177.0, "gene_names": "Best1;Best1;CG6264;Dbest;Dmel\\CG6264;Dmel_CG6264;anon-WO0118547.380;best;dBest1;dbest1;dmBest1", "protein_name": "", "disease": [ { "disease_id": "DOID:0050661", "name": "vitelliform macular dystrophy", "description": "A macular degeneration that it is characterized by the disruption of cells in a small area near the center of the retina, the macula and may cause progressive vision loss.", "url": "https://disease-ontology.org/term/DOID:0050661", "evidence": [ { "id": "0050661", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050661" } ], "weight": 0.0 }, { "disease_id": "DOID:0050662", "name": "bestrophinopathy", "description": "A macular degeneration that is characterized by central vision loss, an absent electrooculogram light rise and a reduced electroretinogram, has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the BEST1 gene on chromosome 11q12.", "url": "https://disease-ontology.org/term/DOID:0050662", "evidence": [ { "id": "0050662", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050662" } ], "weight": 0.0 }, { "disease_id": "DOID:0080685", "name": "aortic dissection", "description": "An aortic disease that is characterized by tearing of the intimal layer of the aorta resulting in separation of the layers of the aortic wall.", "url": "https://disease-ontology.org/term/DOID:0080685", "evidence": [ { "id": "0080685", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080685" } ], "weight": 0.0 }, { "disease_id": "DOID:0110396", "name": "retinitis pigmentosa 50", "description": "A retinitis pigmentosa that has_material_basis_in mutation in the BEST1 gene on chromosome 11q13.", "url": "https://disease-ontology.org/term/DOID:0110396", "evidence": [ { "id": "0110396", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110396" } ], "weight": 0.0 }, { "disease_id": "DOID:0111569", "name": "autosomal dominant vitreoretinochoroidopathy", "description": "A hereditary retinal dystrophy characterized by abnormal chorioretinal hypopigmentation and hyperpigmentation typically lying between the vortex veins and the ora serrata for 360 degrees and other ocular developmental anomalies that has_material_basis_in heterozygous mutation in the BEST1 gene on chromosome 11q12.3.", "url": "https://disease-ontology.org/term/DOID:0111569", "evidence": [ { "id": "0111569", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111569" } ], "weight": 0.0 }, { "disease_id": "DOID:4448", "name": "macular degeneration", "description": "A retinal degeneration characterized by gradual deterioration of light-sensing cells in the tissues at the back of the eye and has_symptom vision loss.", "url": "https://disease-ontology.org/term/DOID:4448", "evidence": [ { "id": "4448", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4448" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "volume-sensitive chloride channel activity", "id": "GO:0072320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072320", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K651", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K651" } ], "pmid": "" }, { "name": "intracellularly calcium-gated chloride channel activity", "id": "GO:0005229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005229", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K651", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K651" } ], "pmid": "" }, { "name": "chloride channel activity", "id": "GO:0005254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005254", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K651", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K651" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K651", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K651" } ], "pmid": "" }, { "name": "chloride channel complex", "id": "GO:0034707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034707", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K651", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K651" } ], "pmid": "" } ], "biological_process": [ { "name": "cell volume homeostasis", "id": "GO:0006884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006884", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K651", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K651" } ], "pmid": "" }, { "name": "chloride transport", "id": "GO:0006821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006821", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K651", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K651" } ], "pmid": "" }, { "name": "intracellular water homeostasis", "id": "GO:0009992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009992", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K651", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K651" } ], "pmid": "" }, { "name": "chloride transmembrane transport", "id": "GO:1902476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902476", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K651", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K651" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4K651-1", "start_pos": "498", "end_pos": "498", "site_lbl": "Thr498", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 498, "start_aa": "Thr", "end_pos": 498, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr498", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A0A0B4K651-1" }, { "uniprot_canonical_ac": "A1Z7I1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z7I1", "url": "https://www.uniprot.org/uniprotkb/A1Z7I1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 620, "chemical_mass": 71227.0, "gene_names": "Dmel\\CG14744;CG14744;Dmel\\CG14744;Dmel_CG14744", "protein_name": "Sodium/calcium exchanger membrane region domain-containing protein", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A1Z7I1", "url": "https://www.uniprot.org/uniprotkb/A1Z7I1" } ], "pmid": "" }, { "name": "mitochondrial crista", "id": "GO:0030061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030061", "evidence": [ { "database": "UniProtKB", "id": "A1Z7I1", "url": "https://www.uniprot.org/uniprotkb/A1Z7I1" } ], "pmid": "" } ], "biological_process": [ { "name": "calcium ion transport", "id": "GO:0006816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006816", "evidence": [ { "database": "UniProtKB", "id": "A1Z7I1", "url": "https://www.uniprot.org/uniprotkb/A1Z7I1" } ], "pmid": "" }, { "name": "intracellular calcium ion homeostasis", "id": "GO:0006874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "database": "UniProtKB", "id": "A1Z7I1", "url": "https://www.uniprot.org/uniprotkb/A1Z7I1" } ], "pmid": "" }, { "name": "monoatomic cation transport", "id": "GO:0006812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006812", "evidence": [ { "database": "UniProtKB", "id": "A1Z7I1", "url": "https://www.uniprot.org/uniprotkb/A1Z7I1" } ], "pmid": "" }, { "name": "mitochondrial calcium ion homeostasis", "id": "GO:0051560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051560", "evidence": [ { "database": "UniProtKB", "id": "A1Z7I1", "url": "https://www.uniprot.org/uniprotkb/A1Z7I1" } ], "pmid": "" } ], "molecular_function": [ { "name": "antiporter activity", "id": "GO:0015297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015297", "evidence": [ { "database": "UniProtKB", "id": "A1Z7I1", "url": "https://www.uniprot.org/uniprotkb/A1Z7I1" } ], "pmid": "" }, { "name": "calcium:sodium antiporter activity", "id": "GO:0005432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005432", "evidence": [ { "database": "UniProtKB", "id": "A1Z7I1", "url": "https://www.uniprot.org/uniprotkb/A1Z7I1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1Z7I1-1" }, { "uniprot_canonical_ac": "A1ZAW0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1722, "chemical_mass": 197765.0, "gene_names": "Dcr-2;CG6493;DCR-2;DCR2;DICER-2;DICER;Dcr-2;Dcr2;Dcr;Dicer-II;Dicer2;Dicer;DmDcr-2;Dmel\\CG6493;Dmel_CG6493;cg6493;dDcr2;dcr-2;dcr2;dcr;dic2;dicer-2;dicer2;dicer;dmDcr-2", "protein_name": "Endoribonuclease Dcr-2", "disease": [], "biological_process": [ { "name": "RISC complex assembly", "id": "GO:0070922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070922", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "locomotory behavior", "id": "GO:0007626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007626", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "positive regulation of defense response to virus by host", "id": "GO:0002230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002230", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated post-transcriptional gene silencing", "id": "GO:0035194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035194", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "siRNA processing", "id": "GO:0030422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030422", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "cellular response to virus", "id": "GO:0098586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098586", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "apoptotic DNA fragmentation", "id": "GO:0006309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006309", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "positive regulation of innate immune response", "id": "GO:0045089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045089", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "detection of virus", "id": "GO:0009597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009597", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "RNAi-mediated antiviral immune response", "id": "GO:0009616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009616", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "dosage compensation by hyperactivation of X chromosome", "id": "GO:0009047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009047", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "positive regulation of Toll signaling pathway", "id": "GO:0045752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045752", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "global gene silencing by mRNA cleavage", "id": "GO:0098795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098795", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "lncRNA catabolic process", "id": "GO:0110064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110064", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "siRNA binding", "id": "GO:0035197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035197", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "ribonuclease III activity", "id": "GO:0004525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004525", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "deoxyribonuclease I activity", "id": "GO:0004530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004530", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "ATP-dependent activity, acting on RNA", "id": "GO:0008186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008186", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "cytoplasmic ribonucleoprotein granule", "id": "GO:0036464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036464", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "RISC complex", "id": "GO:0016442", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016442", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "RISC-loading complex", "id": "GO:0070578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070578", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "1566", "end_pos": "1566", "site_lbl": "Thr1566", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1566, "start_aa": "Thr", "end_pos": 1566, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1566", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "1210", "end_pos": "1210", "site_lbl": "Glu1210", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "V", "comment": "No effect on RNAi silencing activity.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "15066283", "url": "https://glygen.org/publication/PubMed/15066283" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "1217", "end_pos": "1217", "site_lbl": "Asp1217", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Unable to unwind blunt termini (BLT) dsRNAs and fails to rescue loss of RNA silencing activity in mutants. No effect on binding to BLT or 3' overhanging (3'ovr) termini dsRNAs; when associated with A-1476. No effect on binding to 3' overhanging (3'ovr) termini but abolishes binding to BLT dsRNAs; when associated with A-34 and A-1476.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "25891075", "url": "https://glygen.org/publication/PubMed/25891075" }, { "database": "PubMed", "id": "29269422", "url": "https://glygen.org/publication/PubMed/29269422" }, { "database": "PubMed", "id": "27872309", "url": "https://glygen.org/publication/PubMed/27872309" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "1237", "end_pos": "1237", "site_lbl": "Glu1237", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "No effect on RNAi silencing activity.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "15066283", "url": "https://glygen.org/publication/PubMed/15066283" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "1330", "end_pos": "1330", "site_lbl": "Arg1330", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Loss of dimerization, likely affecting formation of the initial binding complex with loqs and dsRNA.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "35768513", "url": "https://glygen.org/publication/PubMed/35768513" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "1371", "end_pos": "1371", "site_lbl": "Glu1371", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "K", "comment": "Loss of RNAi silencing activity. Decreased processing of dsRNAs into SiRNAs. No effect on mRNA cleavage.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "15066283", "url": "https://glygen.org/publication/PubMed/15066283" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "1476", "end_pos": "1476", "site_lbl": "Asp1476", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Unable to unwind blunt termini (BLT) dsRNAs and fails to rescue loss of RNA silencing activity in mutants. No effect on binding to BLT or 3' overhanging (3'ovr) termini dsRNAs; when associated with A-1217. No effect on binding to 3' overhanging (3'ovr) termini but abolishes binding to BLT dsRNAs; when associated with A-34 and A-1217.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "25891075", "url": "https://glygen.org/publication/PubMed/25891075" }, { "database": "PubMed", "id": "29269422", "url": "https://glygen.org/publication/PubMed/29269422" }, { "database": "PubMed", "id": "27872309", "url": "https://glygen.org/publication/PubMed/27872309" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "1617", "end_pos": "1617", "site_lbl": "Glu1617", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "K", "comment": "Loss of RNAi silencing activity. Decreased processing of dsRNAs into SiRNAs. No effect on mRNA cleavage.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "15066283", "url": "https://glygen.org/publication/PubMed/15066283" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "173", "end_pos": "173", "site_lbl": "Gly173", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "E", "comment": "Decreased production of siRNAs from dsRNA precursors.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "15066283", "url": "https://glygen.org/publication/PubMed/15066283" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "225", "end_pos": "225", "site_lbl": "Phe225", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "G", "comment": "Reduced RNAi activity due to decreased generation of siRNAs from endogenous and viral dsRNAs. In vitro, abolishes ATP-dependent cleavage of blunt termini (BLT) dsRNAs but has no effect on ATP-independent cleavage of 3' overhanging (3'ovr) termini dsRNAs. Decreased binding affinities for BLT and 3'ovr dsRNAs. Binding affinity for BLT dsRNAs is further decreased by addition of ATP. Also displays severely reduced binding to loqs (isoform PD). No effect on ATP hydrolysis. Abolishes binding to BLT and 3'ovr dsRNAs; when associated with A-493 and A-596.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "29269422", "url": "https://glygen.org/publication/PubMed/29269422" }, { "database": "PubMed", "id": "32843367", "url": "https://glygen.org/publication/PubMed/32843367" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Gly31", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "R", "comment": "Disrupts ATP binding and thus ATP hydrolysis. Also effects binding to dsRNA substrates and siRNA unwinding by the RISC-loading complex is decreased. Severely reduced RNAi activity due to decreased generation of siRNAs from endogenous and viral dsRNAs. Abolishes ATP-dependent cleavage of blunt termini (BLT) dsRNAs but has no effect on ATP-independent cleavage of 3' overhanging (3'ovr) termini dsRNAs. Decreased binding affinities for BLT and 3'ovr dsRNAs. Also reduces binding to loqs. Fails to rescue loss of RNA silencing activity in mutants.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "21419681", "url": "https://glygen.org/publication/PubMed/21419681" }, { "database": "PubMed", "id": "32843367", "url": "https://glygen.org/publication/PubMed/32843367" }, { "database": "PubMed", "id": "15550672", "url": "https://glygen.org/publication/PubMed/15550672" }, { "database": "PubMed", "id": "27872309", "url": "https://glygen.org/publication/PubMed/27872309" }, { "database": "PubMed", "id": "15066283", "url": "https://glygen.org/publication/PubMed/15066283" }, { "database": "PubMed", "id": "34590626", "url": "https://glygen.org/publication/PubMed/34590626" }, { "database": "PubMed", "id": "24488111", "url": "https://glygen.org/publication/PubMed/24488111" }, { "database": "PubMed", "id": "34257295", "url": "https://glygen.org/publication/PubMed/34257295" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "324", "end_pos": "324", "site_lbl": "Arg324", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "E", "comment": "Decreased binding to r2d2.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "35768503", "url": "https://glygen.org/publication/PubMed/35768503" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "331", "end_pos": "331", "site_lbl": "Glu331", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "R", "comment": "Decreased binding to r2d2.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "35768503", "url": "https://glygen.org/publication/PubMed/35768503" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "34", "end_pos": "34", "site_lbl": "Lys34", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "ATPase-defective. Unable to unwind blunt termini (BLT) dsRNAs but is able to bind BLT dsRNAs. No effect on binding to 3' overhanging (3'ovr) termini but abolishes binding to BLT dsRNAs; when associated with A-1217 and A-1476.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "25891075", "url": "https://glygen.org/publication/PubMed/25891075" }, { "database": "PubMed", "id": "29269422", "url": "https://glygen.org/publication/PubMed/29269422" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "500", "end_pos": "500", "site_lbl": "Ala500", "weight": 0.0, "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "V", "comment": "Increased viral replication of the Sindbis virus (SINV).", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "24009507", "url": "https://glygen.org/publication/PubMed/24009507" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "743", "end_pos": "743", "site_lbl": "His743", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Partially rescues RNA silencing activity in mutants. Abolishes cleavage of 3' overhanging (3'ovr) termini dsRNAs but has no effect on cleavage of blunt termini (BLT) dsRNAs, when associated with A-752, A-759, A-943 and A-956.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "27872309", "url": "https://glygen.org/publication/PubMed/27872309" }, { "database": "PubMed", "id": "35768503", "url": "https://glygen.org/publication/PubMed/35768503" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "752", "end_pos": "752", "site_lbl": "Arg752", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Decreased siRNA length fidelity. Abundance of 21-nucleotide siRNAs produced by the enzyme is decreased whereas the abundance of both 20- and 22-nucleotide siRNAs is increased. Partially rescues RNA silencing activity in mutants. Abolishes cleavage of 3' overhanging (3'ovr) termini dsRNAs but has no effect on cleavage of blunt termini (BLT) dsRNAs, when associated with A-743, A-759, A-943 and A-956.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "27872309", "url": "https://glygen.org/publication/PubMed/27872309" }, { "database": "PubMed", "id": "35768503", "url": "https://glygen.org/publication/PubMed/35768503" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "759", "end_pos": "759", "site_lbl": "Arg759", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Decreased siRNA length fidelity. Abundance of 21-nucleotide siRNAs produced by the enzyme is decreased whereas the abundance of both 20- and 22-nucleotide siRNAs is increased. Partially rescues RNA silencing activity in mutants. Abolishes cleavage of 3' overhanging (3'ovr) termini dsRNAs but has no effect on cleavage of blunt termini (BLT) dsRNAs, when associated with A-743, A-752, A-943 and A-956.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "32843367", "url": "https://glygen.org/publication/PubMed/32843367" }, { "database": "PubMed", "id": "27872309", "url": "https://glygen.org/publication/PubMed/27872309" }, { "database": "PubMed", "id": "35768503", "url": "https://glygen.org/publication/PubMed/35768503" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "943", "end_pos": "943", "site_lbl": "Arg943", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Decreased siRNA length fidelity. Abundance of 21-nucleotide siRNAs produced by the enzyme is decreased whereas the abundance of both 20- and 22-nucleotide siRNAs is increased. However, has no effect on RNA cleavage rates, when associated with A-956. Decreased siRNA length fidelity, partially rescues RNA silencing activity in mutants and abolishes cleavage of 3' overhanging (3'ovr) termini dsRNAs but has no effect on cleavage of blunt termini (BLT) dsRNAs, when associated with A-743, A-752, A-759 and A-956. Abolishes binding to BLT and 3'ovr dsRNAs; when associated with G-225 and A-956.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "32843367", "url": "https://glygen.org/publication/PubMed/32843367" }, { "database": "PubMed", "id": "29269422", "url": "https://glygen.org/publication/PubMed/29269422" }, { "database": "PubMed", "id": "27872309", "url": "https://glygen.org/publication/PubMed/27872309" } ] }, { "sequence_org": "R", "sequence_mut": "E", "comment": "Decreased siRNA length fidelity. Abundance of 21-nucleotide siRNAs produced by the enzyme is decreased whereas the abundance of both 20- and 22-nucleotide siRNAs is increased. However, has no effect on RNA cleavage rates, when associated with E-956.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "27872309", "url": "https://glygen.org/publication/PubMed/27872309" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "956", "end_pos": "956", "site_lbl": "Arg956", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Decreased siRNA length fidelity. Abundance of 21-nucleotide siRNAs produced by the enzyme is decreased whereas the abundance of both 20- and 22-nucleotide siRNAs is increased. However, has no effect on RNA cleavage rates when associated with A-943. Partially rescues RNA silencing activity in mutants. Abolishes cleavage of 3' overhanging (3'ovr) termini dsRNAs but has no effect on cleavage of blunt termini (BLT) dsRNAs, when associated with A-743, A-752, A-759 and A-943. Abolishes binding to BLT and 3'ovr dsRNAs; when associated with G-225 and A-493.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "29269422", "url": "https://glygen.org/publication/PubMed/29269422" }, { "database": "PubMed", "id": "32843367", "url": "https://glygen.org/publication/PubMed/32843367" }, { "database": "PubMed", "id": "27872309", "url": "https://glygen.org/publication/PubMed/27872309" } ] }, { "sequence_org": "R", "sequence_mut": "E", "comment": "Decreased siRNA length fidelity. Abundance of 21-nucleotide siRNAs produced by the enzyme is decreased whereas the abundance of both 20- and 22-nucleotide siRNAs is increased. However, has no effect on RNA cleavage rates, when associated with E-943.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "27872309", "url": "https://glygen.org/publication/PubMed/27872309" } ] } ] } ], "record_id": "A1ZAW0-1" }, { "uniprot_canonical_ac": "A0A126GUN8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A126GUN8", "url": "https://www.uniprot.org/uniprotkb/A0A126GUN8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 760, "chemical_mass": 83489.0, "gene_names": "Klp54D;CG15844;CG43323;DmKlp54D;Dmel\\CG43323;Dmel_CG43323;KIF 12;KIF12;KLP1;KLP54D;Klp1;Klp54D", "protein_name": "Kinesin-like protein", "disease": [ { "disease_id": "DOID:0070221", "name": "progressive familial intrahepatic cholestasis", "description": "An intrahepatic cholestasis characterized by early onset of chronic unremitting cholestasis of hepatocellular origin that progresses to hepatic fibrosis, cirrhosis, and end-stage liver disease before adulthood.", "url": "https://disease-ontology.org/term/DOID:0070221", "evidence": [ { "id": "0070221", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070221" } ], "weight": 0.0 }, { "disease_id": "DOID:0080547", "name": "metabolic dysfunction-associated steatohepatitis", "description": "A metabolic dysfunction-associated steatotic liver disease characterized by the presence of inflammation with hepatocyte injury such as ballooning, with or without fibrosis.", "url": "https://disease-ontology.org/term/DOID:0080547", "evidence": [ { "id": "0080547", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080547" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A126GUN8", "url": "https://www.uniprot.org/uniprotkb/A0A126GUN8" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A126GUN8", "url": "https://www.uniprot.org/uniprotkb/A0A126GUN8" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "A0A126GUN8", "url": "https://www.uniprot.org/uniprotkb/A0A126GUN8" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A126GUN8", "url": "https://www.uniprot.org/uniprotkb/A0A126GUN8" } ], "pmid": "" } ], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A126GUN8", "url": "https://www.uniprot.org/uniprotkb/A0A126GUN8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A126GUN8", "url": "https://www.uniprot.org/uniprotkb/A0A126GUN8" } ], "pmid": "" }, { "name": "kinesin complex", "id": "GO:0005871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005871", "evidence": [ { "database": "UniProtKB", "id": "A0A126GUN8", "url": "https://www.uniprot.org/uniprotkb/A0A126GUN8" } ], "pmid": "" } ], "biological_process": [ { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "A0A126GUN8", "url": "https://www.uniprot.org/uniprotkb/A0A126GUN8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A126GUN8-1", "start_pos": "666", "end_pos": "666", "site_lbl": "Thr666", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 666, "start_aa": "Thr", "end_pos": 666, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr666", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A0A126GUN8-1" }, { "uniprot_canonical_ac": "A0A0B4K6N2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6N2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6N2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 520, "chemical_mass": 59473.0, "gene_names": "FoxP;CG16899;CG32937;CG43067;DmFoxP;Dmcg16899;Dmel\\CG43067;Dmel_CG43067;FoxP;dFoxP;fd85E", "protein_name": "", "disease": [ { "disease_id": "DOID:0050200", "name": "Korean hemorrhagic fever", "description": "A hemorrhagic fever with renal syndrome that results_in infection located_in kidney, has_material_basis_in Hantaan virus, which is transmitted_by the eurasian field mouse, Apodemus agrarius, or has_material_basis_in Seoul virus, which is transmitted_by norwegian rat, Rattus norvegicus. The infection has_symptom headache, has_symptom back pain, has_symptom abdominal pain, has_symptom fever, has_symptom chills, has_symptom nausea, has_symptom blurred vision, has_symptom flushing of the face, has_symptom redness of the eyes, has_symptom rash, has_symptom low blood pressure, has_symptom acute shock, has_symptom vascular leakage, and has_symptom acute kidney failure, which can cause severe fluid overload.", "url": "https://disease-ontology.org/term/DOID:0050200", "evidence": [ { "id": "0050200", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050200" } ], "weight": 0.0 }, { "disease_id": "DOID:0050523", "name": "adult T-cell leukemia/lymphoma", "description": "A T-cell acute leukemia that results_in abnormal increase of lymphocytes, derives_from T-cells, has_material_basis_in human T-cell leukemia virus type 1 (Deltaretrovirus priTlym1), which is transmitted_by sexual contact, transmitted_by contaminated needles used by intravenous-drug users, and transmitted_by breast feeding. The infection results_in_formation_of skin lesions.", "url": "https://disease-ontology.org/term/DOID:0050523", "evidence": [ { "id": "0050523", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050523" } ], "weight": 0.0 }, { "disease_id": "DOID:0060038", "name": "specific developmental disorder", "description": "A developmental disorder of mental health that categorizes specific learning disabilities and developmental disorders affecting coordination.", "url": "https://disease-ontology.org/term/DOID:0060038", "evidence": [ { "id": "0060038", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060038" } ], "weight": 0.0 }, { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0081267", "name": "graft-versus-host disease", "description": "An immune system disease that is characterized by recognition by mature donor T cells, that contaminate the allogeneic bone marrow, of the recipient's tissue as foreign, causing a severe inflammatory disease characterized by rashes, diarrhea, and liver disease, and that has_material_basis_in an associated with variation in the interleukin-10 gene (IL10) on chromosome 1q32.", "url": "https://disease-ontology.org/term/DOID:0081267", "evidence": [ { "id": "0081267", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081267" } ], "weight": 0.0 }, { "disease_id": "DOID:0090110", "name": "immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome", "description": "An autoimmune disease that is characterized by onset in infancy of refractory diarrhea, endocrinopathies, type 1 diabetes mellitus, and dermatitis that has_material_basis_in X-linked recessive mutation in the forkhead box P3 (FOXP3) gene on chromosome Xp11.", "url": "https://disease-ontology.org/term/DOID:0090110", "evidence": [ { "id": "0090110", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090110" } ], "weight": 0.0 }, { "disease_id": "DOID:0090131", "name": "complex cortical dysplasia with other brain malformations", "description": "A brain disease characterized by aberrant neuronal migration and disturbed axonal guidance resulting in variable brain malformations.", "url": "https://disease-ontology.org/term/DOID:0090131", "evidence": [ { "id": "0090131", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090131" } ], "weight": 0.0 }, { "disease_id": "DOID:0111275", "name": "speech-language disorder-1", "description": "A speech disorder characterized by severe orofacial dyspraxia resulting in largely incomprehensible speech that has_material_basis_in heterozygous mutation in FOXP2 on 7q31.1.", "url": "https://disease-ontology.org/term/DOID:0111275", "evidence": [ { "id": "0111275", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111275" } ], "weight": 0.0 }, { "disease_id": "DOID:0111331", "name": "intellectual disability-severe speech delay-mild dysmorphism syndrome", "description": "A syndromic intellectual disability characterized by global developmental delay with moderate to severe speech delay, dysmorphic craniofacial features, and gross motor skill delays that particularly affects expressive speech that has_material_basis_in heterozygous mutation in the FOXP1 gene on chromosome 3p13.", "url": "https://disease-ontology.org/term/DOID:0111331", "evidence": [ { "id": "0111331", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111331" } ], "weight": 0.0 }, { "disease_id": "DOID:106", "name": "pleural tuberculosis", "description": "An extrapulmonary tuberculosis that results_in lymphocyte-predominant exudative pleural effusion, located_in pleura. This results from an allergic response to tuberculoprotein causing the permeabiltity of the pleural vasculature to alter leading to a sub-pleural caseous focus rupture into the pleural sac.", "url": "https://disease-ontology.org/term/DOID:106", "evidence": [ { "id": "106", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:106" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:1094", "name": "attention deficit hyperactivity disorder", "description": "A specific developmental disorder that is characterized by co-existence of attentional problems and hyperactivity, with each behavior occurring infrequently alone and symptoms starting before seven years of age.", "url": "https://disease-ontology.org/term/DOID:1094", "evidence": [ { "id": "1094", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1094" } ], "weight": 0.0 }, { "disease_id": "DOID:11166", "name": "Human papillomavirus infectious disease", "description": "A viral infectious disease that has_material_basis_in human papillomaviruses, which establish productive infections only in the stratified epithelium of the skin or mucous membranes. These viruses cause warts and sometimes tumors. They are transmitted_by sexual contact.", "url": "https://disease-ontology.org/term/DOID:11166", "evidence": [ { "id": "11166", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11166" } ], "weight": 0.0 }, { "disease_id": "DOID:11168", "name": "anogenital venereal wart", "description": "A viral infectious disease that results_in infection located_in skin of vagina, cervix, uterus, anus, penis, scrotum, mouth, or throat, has_material_basis_in human papillomaviruses (types 6 and 11), which are transmitted_by direct contact with the skin during oral, genital, or anal sex with an infected partner. The infection has_symptom anogenital warts.", "url": "https://disease-ontology.org/term/DOID:11168", "evidence": [ { "id": "11168", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11168" } ], "weight": 0.0 }, { "disease_id": "DOID:11263", "name": "chlamydia", "description": "A commensal bacterial infectious disease that is caused by Chlamydia trachomatis.", "url": "https://disease-ontology.org/term/DOID:11263", "evidence": [ { "id": "11263", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11263" } ], "weight": 0.0 }, { "disease_id": "DOID:12236", "name": "primary biliary cholangitis", "description": "A liver cirrhosis characterized by chronic and slow progressive destruction of intrahepatic bile ducts.", "url": "https://disease-ontology.org/term/DOID:12236", "evidence": [ { "id": "12236", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12236" } ], "weight": 0.0 }, { "disease_id": "DOID:12365", "name": "malaria", "description": "A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle.", "url": "https://disease-ontology.org/term/DOID:12365", "evidence": [ { "id": "12365", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12365" } ], "weight": 0.0 }, { "disease_id": "DOID:1255", "name": "trichostrongyloidiasis", "description": "A parasitic helminthiasis infectious disease that involves parasitic infection of animals and humans by nematodes of the superfamily Trichostrongyloidea.", "url": "https://disease-ontology.org/term/DOID:1255", "evidence": [ { "id": "1255", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1255" } ], "weight": 0.0 }, { "disease_id": "DOID:12849", "name": "autistic disorder", "description": "An autism spectrum disorder that is characterized by symptoms across all three symptom domains (communication, social, restricted repetitive interests and behaviors), delayed language development, and symptom onset prior to age 3 years.", "url": "https://disease-ontology.org/term/DOID:12849", "evidence": [ { "id": "12849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12849" } ], "weight": 0.0 }, { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 }, { "disease_id": "DOID:1459", "name": "hypothyroidism", "description": "A thyroid gland disease which involves an underproduction of thyroid hormone.", "url": "https://disease-ontology.org/term/DOID:1459", "evidence": [ { "id": "1459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1459" } ], "weight": 0.0 }, { "disease_id": "DOID:1470", "name": "major depressive disorder", "description": "A depressive disorder that is characterized by at least two weeks of loss of interest or pleasure in normally enjoyable activities or depressed mood along with additional cognitive or somatic impairments such as appetite or weight changes, sleep difficulties, psychomotor agitation or retardation, fatigue or loss of energy, diminished ability to think or concentrate, feelings of worthlessness or excessive guilt, and suicidality.", "url": "https://disease-ontology.org/term/DOID:1470", "evidence": [ { "id": "1470", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1470" } ], "weight": 0.0 }, { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 }, { "disease_id": "DOID:1883", "name": "hepatitis C", "description": "A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in hepatitis C virus (Hepacivirus hominis), which is transmitted_by blood from an infected person enters the body of an uninfected person. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice.", "url": "https://disease-ontology.org/term/DOID:1883", "evidence": [ { "id": "1883", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1883" } ], "weight": 0.0 }, { "disease_id": "DOID:2043", "name": "hepatitis B", "description": "A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in Hepatitis B virus (Orthohepadnavirus hominoidei), which is transmitted_by sexual contact, blood transfusions, or fomites like needles or syringes. The infection has_symptom fever, fatigue, loss of appetite, nausea, vomiting, abdominal pain, clay-colored bowel movements, joint pain, and jaundice.", "url": "https://disease-ontology.org/term/DOID:2043", "evidence": [ { "id": "2043", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2043" } ], "weight": 0.0 }, { "disease_id": "DOID:2799", "name": "bronchiolitis obliterans", "description": "A obstructive lung disease involving obstruction of the bronchioles due to inflammation and fibrosis which occurs as a complication of various lung conditions or physiological insults.", "url": "https://disease-ontology.org/term/DOID:2799", "evidence": [ { "id": "2799", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2799" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:289", "name": "endometriosis", "description": "A female reproductive system disease characterized by the growth of endometrial tissue outside the uterine body.", "url": "https://disease-ontology.org/term/DOID:289", "evidence": [ { "id": "289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:289" } ], "weight": 0.0 }, { "disease_id": "DOID:2938", "name": "Epstein-Barr virus infectious disease", "description": "A viral infectious disease that has_material_basis_in Human gammaherpesvirus 4 (Lymphocryptovirus humangamma4).", "url": "https://disease-ontology.org/term/DOID:2938", "evidence": [ { "id": "2938", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2938" } ], "weight": 0.0 }, { "disease_id": "DOID:2957", "name": "pulmonary tuberculosis", "description": "A tuberculosis that is a contagious disease located_in lungs. The infection has_symptom fever, has_symptom cough, has_symptom difficulty in breathing, has_symptom inflammatory infiltrations, has_symptom formation of tubercles, has_symptom caseation, has_symptom pleural effusion, and has_symptom fibrosis.", "url": "https://disease-ontology.org/term/DOID:2957", "evidence": [ { "id": "2957", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2957" } ], "weight": 0.0 }, { "disease_id": "DOID:321", "name": "HTLV-1-associated myelopathy/tropical spastic paraparesis", "description": "A viral infectious disease that results in inflammation located in spinal cord, has_material_basis_in human T-cell leukemia virus type 1 (Deltaretrovirus priTlym1), which is transmitted by sexual contact, and transmitted by breast feeding. The infection has symptom spastic weakness of both legs, has symptom muscle stiffness, has symptom sensory disturbance, and has symptom spasms.", "url": "https://disease-ontology.org/term/DOID:321", "evidence": [ { "id": "321", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:321" } ], "weight": 0.0 }, { "disease_id": "DOID:3744", "name": "cervical squamous cell carcinoma", "description": "A cervix carcinoma that has_material_basis_in squamous cells of the cervix.", "url": "https://disease-ontology.org/term/DOID:3744", "evidence": [ { "id": "3744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3744" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:401", "name": "multidrug-resistant tuberculosis", "description": "A tuberculosis that is resistant to isoniazid and rifampicin, the two most powerful first-line anti-TB drugs.", "url": "https://disease-ontology.org/term/DOID:401", "evidence": [ { "id": "401", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:401" } ], "weight": 0.0 }, { "disease_id": "DOID:4166", "name": "syphilis", "description": "A primary bacterial infectious disease that is a sexually transmitted systemic disease, has_material_basis_in Treponema pallidum subsp pallidum, which is transmitted_by sexual contact, transmitted_by blood product transfusion, transmitted_by congenital method from mother to fetus or transmitted_by contact with infectious lesions. If left untreated, produces chancres, rashes, and systemic lesions in a clinical course with three stages continued over many years.", "url": "https://disease-ontology.org/term/DOID:4166", "evidence": [ { "id": "4166", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4166" } ], "weight": 0.0 }, { "disease_id": "DOID:4186", "name": "articulation disorder", "description": "A speech disorder that involves mispronouncing speech sounds by omitting, distorting, substituting, or adding sounds which can make speech difficult to understand.", "url": "https://disease-ontology.org/term/DOID:4186", "evidence": [ { "id": "4186", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4186" } ], "weight": 0.0 }, { "disease_id": "DOID:4428", "name": "dyslexia", "description": "A reading disorder resulting from a developmental reading disability involving the inability to process graphic symbols resulting in impairment of reading ability.", "url": "https://disease-ontology.org/term/DOID:4428", "evidence": [ { "id": "4428", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4428" } ], "weight": 0.0 }, { "disease_id": "DOID:4914", "name": "esophagus adenocarcinoma", "description": "An esophageal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:4914", "evidence": [ { "id": "4914", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4914" } ], "weight": 0.0 }, { "disease_id": "DOID:4928", "name": "intrahepatic cholangiocarcinoma", "description": "A cholangiocarcinoma that arises from the intrahepatic bile duct epithelium in any site of the intrahepatic biliary tree.", "url": "https://disease-ontology.org/term/DOID:4928", "evidence": [ { "id": "4928", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4928" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:8283", "name": "peritonitis", "description": "A gastrointestinal system disease that involves inflammation of the peritoneum resulting from perforation of the gastrointestinal tract, which produces immediate chemical inflammation followed shortly by infection from intestinal organisms. Peritonitis can also result from appendicitis, diverticulitis, strangulating intestinal obstruction, pancreatitis, pelvic inflammatory disease, mesenteric ischemia, intraperitoneal blood, barium, or peritoneo-systemic shunts, drains, and dialysis catheters in the peritoneal cavity. The symptoms include abdominal pain and tenderness, fever, fluid in the abdomen, nausea, vomiting and low urine output.", "url": "https://disease-ontology.org/term/DOID:8283", "evidence": [ { "id": "8283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8283" } ], "weight": 0.0 }, { "disease_id": "DOID:8568", "name": "infectious mononucleosis", "description": "A viral infectious disease that results in inflammation, located in pharynx, has_material_basis_in Human herpesvirus 4 (Lymphocryptovirus humangamma4) and has symptom fever, has symptom fatigue, has symptom lymphadenopathy, and has symptom splenomegaly.", "url": "https://disease-ontology.org/term/DOID:8568", "evidence": [ { "id": "8568", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8568" } ], "weight": 0.0 }, { "disease_id": "DOID:9111", "name": "cutaneous leishmaniasis", "description": "A leishmaniasis that involves skin infection caused by Leishmania species, resulting in one or more cutaneous lesions.", "url": "https://disease-ontology.org/term/DOID:9111", "evidence": [ { "id": "9111", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9111" } ], "weight": 0.0 }, { "disease_id": "DOID:9169", "name": "Wiskott-Aldrich syndrome", "description": "A syndrome that is characterized by abnormal immune system function and a reduced ability to form blood clots resulting from a decrease in the number and size of blood cell fragments involved in clotting (microthrombocytopenia).", "url": "https://disease-ontology.org/term/DOID:9169", "evidence": [ { "id": "9169", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9169" } ], "weight": 0.0 }, { "disease_id": "DOID:9206", "name": "Barrett's esophagus", "description": "An esophageal disease characterized by a change of normal esophageal squamous epithelium to a columnar and intestinal-type epithelium.", "url": "https://disease-ontology.org/term/DOID:9206", "evidence": [ { "id": "9206", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9206" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:93", "name": "language disorder", "description": "A communication disorder that involves the processing of linguistic information.", "url": "https://disease-ontology.org/term/DOID:93", "evidence": [ { "id": "93", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:93" } ], "weight": 0.0 }, { "disease_id": "DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.", "url": "https://disease-ontology.org/term/DOID:9744", "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ], "weight": 0.0 }, { "disease_id": "DOID:9955", "name": "hypoplastic left heart syndrome", "description": "A congenital heart disease characterized by abnormal development of the left-sided structures of the heart.", "url": "https://disease-ontology.org/term/DOID:9955", "evidence": [ { "id": "9955", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9955" } ], "weight": 0.0 } ], "biological_process": [ { "name": "operant conditioning", "id": "GO:0035106", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035106", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6N2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6N2" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6N2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6N2" } ], "pmid": "" }, { "name": "locomotion", "id": "GO:0040011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040011", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6N2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6N2" } ], "pmid": "" }, { "name": "male courtship behavior, veined wing generated song production", "id": "GO:0045433", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045433", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6N2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6N2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6N2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6N2" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6N2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6N2" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6N2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6N2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6N2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6N2" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6N2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6N2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6N2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6N2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6N2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6N2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6N2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6N2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4K6N2-1" }, { "uniprot_canonical_ac": "X2JE21-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JE21", "url": "https://www.uniprot.org/uniprotkb/X2JE21" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1484, "chemical_mass": 162616.0, "gene_names": "mmd;CG15603;CG15604;CG42252;CG9163;CT26192;Dmel\\CG42252;Dmel_CG42252;mmd", "protein_name": "", "disease": [ { "disease_id": "DOID:0080434", "name": "developmental and epileptic encephalopathy 61", "description": "A developmental and epileptic encephalopathy that has_material_basis_in homozygous or compound heterozygous mutation in the ADAM22 gene on chromosome 7q21.", "url": "https://disease-ontology.org/term/DOID:0080434", "evidence": [ { "id": "0080434", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080434" } ], "weight": 0.0 } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "X2JE21", "url": "https://www.uniprot.org/uniprotkb/X2JE21" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "X2JE21", "url": "https://www.uniprot.org/uniprotkb/X2JE21" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "X2JE21", "url": "https://www.uniprot.org/uniprotkb/X2JE21" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "X2JE21", "url": "https://www.uniprot.org/uniprotkb/X2JE21" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "X2JE21-1" }, { "uniprot_canonical_ac": "X2JAM4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JAM4", "url": "https://www.uniprot.org/uniprotkb/X2JAM4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 4526, "chemical_mass": 496785.0, "gene_names": "Svil;CG1141;CG12790;CG13797;CG13798;CG13799;CG13800;CG16763;CG16764;CG32306;CG33231;CG33232;CG42669;CG45186;Dmel\\CG45186;Dmel_CG45186;Svil;c62E-11", "protein_name": "", "disease": [ { "disease_id": "DOID:0112108", "name": "myofibrillar myopathy 10", "description": "A myofibrillar myopathy characterized by onset of muscle pain, cramping, and exercise fatigue in the first or second decades of life that has_material_basis_in homozygous or compound heterozygous mutation in the SVIL gene on chromosome 10p11.23.", "url": "https://disease-ontology.org/term/DOID:0112108", "evidence": [ { "id": "0112108", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112108" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "X2JAM4", "url": "https://www.uniprot.org/uniprotkb/X2JAM4" } ], "pmid": "" }, { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "X2JAM4", "url": "https://www.uniprot.org/uniprotkb/X2JAM4" } ], "pmid": "" } ], "biological_process": [ { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "X2JAM4", "url": "https://www.uniprot.org/uniprotkb/X2JAM4" } ], "pmid": "" }, { "name": "actin filament capping", "id": "GO:0051693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051693", "evidence": [ { "database": "UniProtKB", "id": "X2JAM4", "url": "https://www.uniprot.org/uniprotkb/X2JAM4" } ], "pmid": "" }, { "name": "barbed-end actin filament capping", "id": "GO:0051016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051016", "evidence": [ { "database": "UniProtKB", "id": "X2JAM4", "url": "https://www.uniprot.org/uniprotkb/X2JAM4" } ], "pmid": "" }, { "name": "actin polymerization or depolymerization", "id": "GO:0008154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008154", "evidence": [ { "database": "UniProtKB", "id": "X2JAM4", "url": "https://www.uniprot.org/uniprotkb/X2JAM4" } ], "pmid": "" }, { "name": "actin filament severing", "id": "GO:0051014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051014", "evidence": [ { "database": "UniProtKB", "id": "X2JAM4", "url": "https://www.uniprot.org/uniprotkb/X2JAM4" } ], "pmid": "" } ], "cellular_component": [ { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "X2JAM4", "url": "https://www.uniprot.org/uniprotkb/X2JAM4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "X2JAM4-1", "start_pos": "1450", "end_pos": "1450", "site_lbl": "Thr1450", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1450, "start_aa": "Thr", "end_pos": 1450, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1450", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "X2JAM4-1", "start_pos": "1993", "end_pos": "1993", "site_lbl": "Thr1993", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1993, "start_aa": "Thr", "end_pos": 1993, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1993", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "X2JAM4-1", "start_pos": "2804", "end_pos": "2804", "site_lbl": "Thr2804", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2804, "start_aa": "Thr", "end_pos": 2804, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2804", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "X2JAM4-1", "start_pos": "494", "end_pos": "494", "site_lbl": "Thr494", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 494, "start_aa": "Thr", "end_pos": 494, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr494", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "X2JAM4-1" }, { "uniprot_canonical_ac": "A0A023GPK8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A023GPK8", "url": "https://www.uniprot.org/uniprotkb/A0A023GPK8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1447, "chemical_mass": 158042.0, "gene_names": "fred;CG12675;CG31774;CG3390;CG3393;CT11413;Dmel\\CG31774;Dmel_CG31774;Fred;fred", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A023GPK8", "url": "https://www.uniprot.org/uniprotkb/A0A023GPK8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A023GPK8", "url": "https://www.uniprot.org/uniprotkb/A0A023GPK8" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A023GPK8", "url": "https://www.uniprot.org/uniprotkb/A0A023GPK8" } ], "pmid": "" } ], "biological_process": [ { "name": "sensory organ development", "id": "GO:0007423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007423", "evidence": [ { "database": "UniProtKB", "id": "A0A023GPK8", "url": "https://www.uniprot.org/uniprotkb/A0A023GPK8" } ], "pmid": "" }, { "name": "adult chitin-based cuticle pattern formation", "id": "GO:0035018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035018", "evidence": [ { "database": "UniProtKB", "id": "A0A023GPK8", "url": "https://www.uniprot.org/uniprotkb/A0A023GPK8" } ], "pmid": "" }, { "name": "compound eye morphogenesis", "id": "GO:0001745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001745", "evidence": [ { "database": "UniProtKB", "id": "A0A023GPK8", "url": "https://www.uniprot.org/uniprotkb/A0A023GPK8" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A023GPK8", "url": "https://www.uniprot.org/uniprotkb/A0A023GPK8" } ], "pmid": "" }, { "name": "regulation of establishment of planar polarity", "id": "GO:0090175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090175", "evidence": [ { "database": "UniProtKB", "id": "A0A023GPK8", "url": "https://www.uniprot.org/uniprotkb/A0A023GPK8" } ], "pmid": "" } ], "molecular_function": [ { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A023GPK8", "url": "https://www.uniprot.org/uniprotkb/A0A023GPK8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A023GPK8-1", "start_pos": "1205", "end_pos": "1205", "site_lbl": "Thr1205", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1205, "start_aa": "Thr", "end_pos": 1205, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1205", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A023GPK8-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Thr135", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 135, "start_aa": "Thr", "end_pos": 135, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr135", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A0A023GPK8-1" }, { "uniprot_canonical_ac": "A8JNK4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 665, "chemical_mass": 74103.0, "gene_names": "Cip4;CG11341;CG15015;CIP4;Cip4;DCIP4;Dmel\\CG15015;Dmel_CG15015;cip4;dCIP4;dcip4", "protein_name": "", "disease": [ { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "GTPase activating protein binding", "id": "GO:0032794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032794", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "cleavage furrow", "id": "GO:0032154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032154", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "vesicle membrane", "id": "GO:0012506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012506", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "plasma membrane organization", "id": "GO:0007009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007009", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "negative regulation of actin nucleation", "id": "GO:0051126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051126", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "mesoderm development", "id": "GO:0007498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007498", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "negative regulation of actin filament polymerization", "id": "GO:0030837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030837", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "plasma membrane tubulation", "id": "GO:0097320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097320", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "regulation of synaptic assembly at neuromuscular junction", "id": "GO:0008582", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008582", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "germarium-derived female germ-line cyst encapsulation", "id": "GO:0030708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030708", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "regulation of adherens junction organization", "id": "GO:1903391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903391", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "cellularization", "id": "GO:0007349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007349", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "imaginal disc-derived wing hair organization", "id": "GO:0035317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035317", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "negative regulation of synaptic assembly at neuromuscular junction", "id": "GO:0045886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045886", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8JNK4-1" }, { "uniprot_canonical_ac": "X2JEY5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JEY5", "url": "https://www.uniprot.org/uniprotkb/X2JEY5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 798, "chemical_mass": 91522.0, "gene_names": "AMPdeam;AMP deam;AMPdeam;CG11058;CG11065;CG15762;CG32626;Dmel\\CG32626;Dmel_CG32626", "protein_name": "AMP deaminase", "disease": [ { "disease_id": "DOID:0051064", "name": "left ventricular failure", "description": "A congestive heart failure that is characterized by dysfunction of the left ventricle, resulting insufficient delivery of blood to vital organs.", "url": "https://disease-ontology.org/term/DOID:0051064", "evidence": [ { "id": "0051064", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051064" } ], "weight": 0.0 }, { "disease_id": "DOID:0060264", "name": "pontocerebellar hypoplasia", "description": "A neurodegenerative disease that is characterized by underdevelopment of the pons and cerebellum.", "url": "https://disease-ontology.org/term/DOID:0060264", "evidence": [ { "id": "0060264", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060264" } ], "weight": 0.0 }, { "disease_id": "DOID:0060278", "name": "pontocerebellar hypoplasia type 9", "description": "A pontocerebellar hypoplasia that is characterized by progressive microcephaly, spasticity, seizure and brain atrophy, has_material_basis_in autosomal recessive inheritance of mutation in the AMPD2 gene.", "url": "https://disease-ontology.org/term/DOID:0060278", "evidence": [ { "id": "0060278", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060278" } ], "weight": 0.0 }, { "disease_id": "DOID:0110814", "name": "hereditary spastic paraplegia 63", "description": "A hereditary spastic paraplegia that has_material_basis_in mutation in the AMPD2 gene on chromosome 1p13.", "url": "https://disease-ontology.org/term/DOID:0110814", "evidence": [ { "id": "0110814", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110814" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "X2JEY5", "url": "https://www.uniprot.org/uniprotkb/X2JEY5" } ], "pmid": "" } ], "molecular_function": [ { "name": "AMP deaminase activity", "id": "GO:0003876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003876", "evidence": [ { "database": "UniProtKB", "id": "X2JEY5", "url": "https://www.uniprot.org/uniprotkb/X2JEY5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "X2JEY5", "url": "https://www.uniprot.org/uniprotkb/X2JEY5" } ], "pmid": "" } ], "biological_process": [ { "name": "IMP salvage", "id": "GO:0032264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032264", "evidence": [ { "database": "UniProtKB", "id": "X2JEY5", "url": "https://www.uniprot.org/uniprotkb/X2JEY5" } ], "pmid": "" }, { "name": "AMP metabolic process", "id": "GO:0046033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046033", "evidence": [ { "database": "UniProtKB", "id": "X2JEY5", "url": "https://www.uniprot.org/uniprotkb/X2JEY5" } ], "pmid": "" }, { "name": "IMP biosynthetic process", "id": "GO:0006188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006188", "evidence": [ { "database": "UniProtKB", "id": "X2JEY5", "url": "https://www.uniprot.org/uniprotkb/X2JEY5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "X2JEY5-1" }, { "uniprot_canonical_ac": "Q9VZ41-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZ41", "url": "https://www.uniprot.org/uniprotkb/Q9VZ41" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 532, "chemical_mass": 60690.0, "gene_names": "SmydA-4;CG11160;Dmel\\CG11160;Dmel_CG11160;SmydA-4", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ41", "url": "https://www.uniprot.org/uniprotkb/Q9VZ41" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ41", "url": "https://www.uniprot.org/uniprotkb/Q9VZ41" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ41", "url": "https://www.uniprot.org/uniprotkb/Q9VZ41" } ], "pmid": "" } ], "molecular_function": [ { "name": "histone deacetylase binding", "id": "GO:0042826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042826", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ41", "url": "https://www.uniprot.org/uniprotkb/Q9VZ41" } ], "pmid": "" }, { "name": "N-methyltransferase activity", "id": "GO:0008170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008170", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ41", "url": "https://www.uniprot.org/uniprotkb/Q9VZ41" } ], "pmid": "" }, { "name": "protein methyltransferase activity", "id": "GO:0008276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008276", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ41", "url": "https://www.uniprot.org/uniprotkb/Q9VZ41" } ], "pmid": "" }, { "name": "S-adenosylmethionine-dependent methyltransferase activity", "id": "GO:0008757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008757", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ41", "url": "https://www.uniprot.org/uniprotkb/Q9VZ41" } ], "pmid": "" }, { "name": "protein-lysine N-methyltransferase activity", "id": "GO:0016279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016279", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ41", "url": "https://www.uniprot.org/uniprotkb/Q9VZ41" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VZ41-1" }, { "uniprot_canonical_ac": "Q9W4S3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W4S3", "url": "https://www.uniprot.org/uniprotkb/Q9W4S3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 558, "chemical_mass": 66127.0, "gene_names": "Dmel\\CG10801;CG10801;Dmel\\CG10801;Dmel_CG10801", "protein_name": "BACK domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W4S3-1" }, { "uniprot_canonical_ac": "Q9W4G6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W4G6", "url": "https://www.uniprot.org/uniprotkb/Q9W4G6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1893, "chemical_mass": 211120.0, "gene_names": "CG2861;Dmel\\CG2861;CG2861;Dmel\\CG2861;Dmel_CG2861", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9W4G6-1", "start_pos": "595", "end_pos": "595", "site_lbl": "Thr595", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 595, "start_aa": "Thr", "end_pos": 595, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr595", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9W4G6-1" }, { "uniprot_canonical_ac": "Q9VVM0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVM0", "url": "https://www.uniprot.org/uniprotkb/Q9VVM0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 630, "chemical_mass": 68916.0, "gene_names": "Dmel\\CG5535;anon-WO0118547.111;CG5535;Dmel\\CG5535;Dmel_CG5535;anon-WO0118547.111", "protein_name": "Cationic amino acid transporter C-terminal domain-containing protein", "disease": [ { "disease_id": "DOID:0111666", "name": "proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome", "description": "A syndrome characterized by hydranencephaly, glomeruloid vasculopathy of the central nervous system and retinal vessels, diffuse clastic ischemic lesions of the brain stem, basal ganglia, and spinal cord with calcifications, and fetal akinesia with arthrogryposis that has_material_basis_in homozygous or compound heterozygous mutation in the FLVCR2 gene on chromosome 14q24.3.", "url": "https://disease-ontology.org/term/DOID:0111666", "evidence": [ { "id": "0111666", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111666" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM0", "url": "https://www.uniprot.org/uniprotkb/Q9VVM0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM0", "url": "https://www.uniprot.org/uniprotkb/Q9VVM0" } ], "pmid": "" } ], "molecular_function": [ { "name": "amino acid transmembrane transporter activity", "id": "GO:0015171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015171", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM0", "url": "https://www.uniprot.org/uniprotkb/Q9VVM0" } ], "pmid": "" }, { "name": "L-ornithine transmembrane transporter activity", "id": "GO:0000064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000064", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM0", "url": "https://www.uniprot.org/uniprotkb/Q9VVM0" } ], "pmid": "" }, { "name": "L-lysine transmembrane transporter activity", "id": "GO:0015189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015189", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM0", "url": "https://www.uniprot.org/uniprotkb/Q9VVM0" } ], "pmid": "" }, { "name": "L-arginine transmembrane transporter activity", "id": "GO:0061459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061459", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM0", "url": "https://www.uniprot.org/uniprotkb/Q9VVM0" } ], "pmid": "" } ], "biological_process": [ { "name": "amino acid transmembrane transport", "id": "GO:0003333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003333", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM0", "url": "https://www.uniprot.org/uniprotkb/Q9VVM0" } ], "pmid": "" }, { "name": "L-arginine import across plasma membrane", "id": "GO:0097638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097638", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM0", "url": "https://www.uniprot.org/uniprotkb/Q9VVM0" } ], "pmid": "" }, { "name": "L-ornithine transmembrane transport", "id": "GO:1903352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903352", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM0", "url": "https://www.uniprot.org/uniprotkb/Q9VVM0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VVM0-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Thr112", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 112, "start_aa": "Thr", "end_pos": 112, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr112", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VVM0-1" }, { "uniprot_canonical_ac": "Q9VR26-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VR26", "url": "https://www.uniprot.org/uniprotkb/Q9VR26" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 456, "chemical_mass": 54834.0, "gene_names": "Dmel\\CG3294;CG3294;Dmel\\CG3294;Dmel_CG3294;cg3294", "protein_name": "", "disease": [ { "disease_id": "DOID:0050908", "name": "myelodysplastic syndrome", "description": "A bone marrow cancer that is characterized by under production of white blood cells, red blood cells and platelets.", "url": "https://disease-ontology.org/term/DOID:0050908", "evidence": [ { "id": "0050908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050908" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q9VR26", "url": "https://www.uniprot.org/uniprotkb/Q9VR26" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VR26", "url": "https://www.uniprot.org/uniprotkb/Q9VR26" } ], "pmid": "" }, { "name": "pre-mRNA 3'-splice site binding", "id": "GO:0030628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030628", "evidence": [ { "database": "UniProtKB", "id": "Q9VR26", "url": "https://www.uniprot.org/uniprotkb/Q9VR26" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q9VR26", "url": "https://www.uniprot.org/uniprotkb/Q9VR26" } ], "pmid": "" }, { "name": "wound healing", "id": "GO:0042060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042060", "evidence": [ { "database": "UniProtKB", "id": "Q9VR26", "url": "https://www.uniprot.org/uniprotkb/Q9VR26" } ], "pmid": "" }, { "name": "spliceosomal complex assembly", "id": "GO:0000245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000245", "evidence": [ { "database": "UniProtKB", "id": "Q9VR26", "url": "https://www.uniprot.org/uniprotkb/Q9VR26" } ], "pmid": "" } ], "cellular_component": [ { "name": "U2AF complex", "id": "GO:0089701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0089701", "evidence": [ { "database": "UniProtKB", "id": "Q9VR26", "url": "https://www.uniprot.org/uniprotkb/Q9VR26" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "Q9VR26", "url": "https://www.uniprot.org/uniprotkb/Q9VR26" } ], "pmid": "" }, { "name": "U12-type spliceosomal complex", "id": "GO:0005689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005689", "evidence": [ { "database": "UniProtKB", "id": "Q9VR26", "url": "https://www.uniprot.org/uniprotkb/Q9VR26" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VR26-1" }, { "uniprot_canonical_ac": "X2JFW7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JFW7", "url": "https://www.uniprot.org/uniprotkb/X2JFW7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 134, "chemical_mass": 14399.0, "gene_names": "Dmel\\CG34331;CG34331;Dmel\\CG34331;Dmel_CG34331", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "X2JFW7-1" }, { "uniprot_canonical_ac": "Q9W4I6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W4I6", "url": "https://www.uniprot.org/uniprotkb/Q9W4I6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 583, "chemical_mass": 62897.0, "gene_names": "Dmel\\CG3081;CG3081;Dmel\\CG3081;Dmel_CG3081;EG:84H4.4", "protein_name": "DUF4812 domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W4I6-1" }, { "uniprot_canonical_ac": "A0A6H2EG35-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EG35", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EG35" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2803, "chemical_mass": 302857.0, "gene_names": "Nuak;CG11870;CG11871;CG11872;CG43143;Dmel\\CG43143;Dmel_CG43143;EMK/KIAA0537;KIAA0537;NUAK;Nuak1;Nuak;Omphk1", "protein_name": "", "disease": [ { "disease_id": "DOID:0060668", "name": "anencephaly", "description": "A congenital nervous system abnormality characterized by failure of the anterior neuropore to close resulting in partial or complete absence of the cranial vault accompanied by absence of overlying tissues, including the brain and cerebral hemispheres, skull and scalp.", "url": "https://disease-ontology.org/term/DOID:0060668", "evidence": [ { "id": "0060668", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060668" } ], "weight": 0.0 }, { "disease_id": "DOID:13223", "name": "uterine fibroid", "description": "An uterine benign neoplasm derived from the smooth muscle layer of the uterus.", "url": "https://disease-ontology.org/term/DOID:13223", "evidence": [ { "id": "13223", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13223" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EG35", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EG35" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EG35", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EG35" } ], "pmid": "" }, { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EG35", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EG35" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EG35", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EG35" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EG35", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EG35" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A6H2EG35-1", "start_pos": "1039", "end_pos": "1039", "site_lbl": "Thr1039", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1039, "start_aa": "Thr", "end_pos": 1039, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1039", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A6H2EG35-1", "start_pos": "1046", "end_pos": "1046", "site_lbl": "Thr1046", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1046, "start_aa": "Thr", "end_pos": 1046, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1046", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A0A6H2EG35", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A6H2EG35" }, { "id": "33925313", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33925313" } ] } ] }, { "uniprot_canonical_ac": "A0A6H2EG35-1", "start_pos": "1047", "end_pos": "1047", "site_lbl": "Ser1047", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1047, "start_aa": "Ser", "end_pos": 1047, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1047", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A0A6H2EG35", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A6H2EG35" }, { "id": "33925313", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33925313" } ] } ] }, { "uniprot_canonical_ac": "A0A6H2EG35-1", "start_pos": "2072", "end_pos": "2072", "site_lbl": "Thr2072", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2072, "start_aa": "Thr", "end_pos": 2072, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2072", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A6H2EG35-1", "start_pos": "2074", "end_pos": "2074", "site_lbl": "Thr2074", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2074, "start_aa": "Thr", "end_pos": 2074, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2074", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A6H2EG35-1", "start_pos": "2519", "end_pos": "2519", "site_lbl": "Thr2519", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2519, "start_aa": "Thr", "end_pos": 2519, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2519", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A6H2EG35-1", "start_pos": "531", "end_pos": "531", "site_lbl": "Thr531", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 531, "start_aa": "Thr", "end_pos": 531, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr531", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A6H2EG35-1", "start_pos": "669", "end_pos": "669", "site_lbl": "Thr669", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 669, "start_aa": "Thr", "end_pos": 669, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr669", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A6H2EG35-1", "start_pos": "713", "end_pos": "713", "site_lbl": "Ser713", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 713, "start_aa": "Ser", "end_pos": 713, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser713", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A0A6H2EG35", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A6H2EG35" }, { "id": "33925313", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33925313" } ] } ] } ], "record_id": "A0A6H2EG35-1" }, { "uniprot_canonical_ac": "A1Z9K9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z9K9", "url": "https://www.uniprot.org/uniprotkb/A1Z9K9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 160, "chemical_mass": 18633.0, "gene_names": "CG13353;Dmel\\CG42288;CG13353;CG42288;Dmel\\CG42288;Dmel_CG42288", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A1Z9K9", "url": "https://www.uniprot.org/uniprotkb/A1Z9K9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1Z9K9-1" }, { "uniprot_canonical_ac": "A0A0B4KHG9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHG9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHG9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 819, "chemical_mass": 92010.0, "gene_names": "Dmel\\CG13643;CG13642;CG13643;Dmel\\CG13643;Dmel_CG13643", "protein_name": "Chitin-binding type-2 domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHG9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHG9" } ], "pmid": "" } ], "molecular_function": [ { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHG9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHG9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4KHG9-1", "start_pos": "312", "end_pos": "312", "site_lbl": "Thr312", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 312, "start_aa": "Thr", "end_pos": 312, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr312", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A0A0B4KHG9-1" }, { "uniprot_canonical_ac": "A1ZBC4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1471, "chemical_mass": 158176.0, "gene_names": "Sik3;CG15072;CG18604;CG42856;Dmel\\CG42856;Dmel_CG42856;EMK/KIAA0999;KIAA0999;SIK3;SIK;Sik3", "protein_name": "non-specific serine/threonine protein kinase", "disease": [], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "pmid": "" }, { "name": "response to starvation", "id": "GO:0042594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042594", "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "pmid": "" }, { "name": "lipid homeostasis", "id": "GO:0055088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055088", "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "pmid": "" }, { "name": "insulin receptor signaling pathway", "id": "GO:0008286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008286", "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "pmid": "" }, { "name": "negative regulation of hippo signaling", "id": "GO:0035331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035331", "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "pmid": "" }, { "name": "negative regulation of triglyceride catabolic process", "id": "GO:0010897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010897", "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "pmid": "" }, { "name": "circadian sleep/wake cycle, sleep", "id": "GO:0050802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050802", "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "pmid": "" }, { "name": "positive regulation of pentose-phosphate shunt", "id": "GO:1905857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905857", "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1ZBC4-1", "start_pos": "1127", "end_pos": "1127", "site_lbl": "Thr1127", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1127, "start_aa": "Thr", "end_pos": 1127, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1127", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A1ZBC4-1" }, { "uniprot_canonical_ac": "Q9W233-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W233", "url": "https://www.uniprot.org/uniprotkb/Q9W233" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 813, "chemical_mass": 89190.0, "gene_names": "Idit;33143;CG13509;CG33143;CG4232;Dmel\\CG33143;Dmel_CG33143;mdcds_16487", "protein_name": "Fibronectin type-III domain-containing protein", "disease": [], "biological_process": [ { "name": "positive regulation of macroautophagy", "id": "GO:0016239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016239", "evidence": [ { "database": "UniProtKB", "id": "Q9W233", "url": "https://www.uniprot.org/uniprotkb/Q9W233" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W233-1" }, { "uniprot_canonical_ac": "A1Z782-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z782", "url": "https://www.uniprot.org/uniprotkb/A1Z782" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 646, "chemical_mass": 71722.0, "gene_names": "Dmel\\CG8726;CG8726;Dmel\\CG8726;Dmel_CG8726", "protein_name": "PX domain-containing protein kinase-like protein", "disease": [ { "disease_id": "DOID:2835", "name": "polycythemia due to hypoxia", "description": "", "url": "https://disease-ontology.org/term/DOID:2835", "evidence": [ { "id": "2835", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2835" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A1Z782", "url": "https://www.uniprot.org/uniprotkb/A1Z782" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A1Z782", "url": "https://www.uniprot.org/uniprotkb/A1Z782" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A1Z782", "url": "https://www.uniprot.org/uniprotkb/A1Z782" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1Z782", "url": "https://www.uniprot.org/uniprotkb/A1Z782" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A1Z782", "url": "https://www.uniprot.org/uniprotkb/A1Z782" } ], "pmid": "" } ], "biological_process": [ { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "A1Z782", "url": "https://www.uniprot.org/uniprotkb/A1Z782" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1Z782-1" }, { "uniprot_canonical_ac": "A1Z830-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z830", "url": "https://www.uniprot.org/uniprotkb/A1Z830" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 485, "chemical_mass": 53881.0, "gene_names": "ptch;CG12128;Dmel\\CG12128;Dmel_CG12128", "protein_name": "28S rRNA (uridine-N(3))-methyltransferase", "disease": [], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A1Z830", "url": "https://www.uniprot.org/uniprotkb/A1Z830" } ], "pmid": "" } ], "molecular_function": [ { "name": "rRNA (uridine-N3-)-methyltransferase activity", "id": "GO:0070042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070042", "evidence": [ { "database": "UniProtKB", "id": "A1Z830", "url": "https://www.uniprot.org/uniprotkb/A1Z830" } ], "pmid": "" }, { "name": "RNA methyltransferase activity", "id": "GO:0008173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008173", "evidence": [ { "database": "UniProtKB", "id": "A1Z830", "url": "https://www.uniprot.org/uniprotkb/A1Z830" } ], "pmid": "" }, { "name": "S-adenosyl-L-methionine binding", "id": "GO:1904047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904047", "evidence": [ { "database": "UniProtKB", "id": "A1Z830", "url": "https://www.uniprot.org/uniprotkb/A1Z830" } ], "pmid": "" } ], "biological_process": [ { "name": "rRNA base methylation", "id": "GO:0070475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070475", "evidence": [ { "database": "UniProtKB", "id": "A1Z830", "url": "https://www.uniprot.org/uniprotkb/A1Z830" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1Z830-1" }, { "uniprot_canonical_ac": "A1Z8F4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z8F4", "url": "https://www.uniprot.org/uniprotkb/A1Z8F4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2577, "chemical_mass": 276829.0, "gene_names": "shn;BEST:SD06302;CG7734;Dmel\\CG7734;EP(2)2359;EP2359;SD06302;SHN;Schnurri;Shn;l(2)04738;quo;shn", "protein_name": "Protein schnurri", "disease": [ { "disease_id": "DOID:0050787", "name": "juvenile polyposis syndrome", "description": "A gastrointestinal system disease that is characterized by predisposition to hamartomatous benign polyps in the gastrointestinal tract, specifically in the stomach, small intestine, colon, and rectum.", "url": "https://disease-ontology.org/term/DOID:0050787", "evidence": [ { "id": "0050787", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050787" } ], "weight": 0.0 }, { "disease_id": "DOID:0070073", "name": "autosomal dominant intellectual developmental disorder 43", "description": "An autosomal dominant intellectual developmental disorder characterized by delayed psychomotor development with impaired intellectual development and poor speech, hypotonia, and nonspecific dysmorphic features that has_material_basis_in an autosomal dominant mutation of the HIVEP2 gene on chromosome 6q24.2.", "url": "https://disease-ontology.org/term/DOID:0070073", "evidence": [ { "id": "0070073", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070073" } ], "weight": 0.0 }, { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A1Z8F4", "url": "https://www.uniprot.org/uniprotkb/A1Z8F4" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A1Z8F4", "url": "https://www.uniprot.org/uniprotkb/A1Z8F4" } ], "pmid": "" }, { "name": "midgut development", "id": "GO:0007494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007494", "evidence": [ { "database": "UniProtKB", "id": "A1Z8F4", "url": "https://www.uniprot.org/uniprotkb/A1Z8F4" } ], "pmid": "" }, { "name": "dendrite morphogenesis", "id": "GO:0048813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048813", "evidence": [ { "database": "UniProtKB", "id": "A1Z8F4", "url": "https://www.uniprot.org/uniprotkb/A1Z8F4" } ], "pmid": "" }, { "name": "ectoderm development", "id": "GO:0007398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007398", "evidence": [ { "database": "UniProtKB", "id": "A1Z8F4", "url": "https://www.uniprot.org/uniprotkb/A1Z8F4" } ], "pmid": "" }, { "name": "Malpighian tubule morphogenesis", "id": "GO:0007443", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007443", "evidence": [ { "database": "UniProtKB", "id": "A1Z8F4", "url": "https://www.uniprot.org/uniprotkb/A1Z8F4" } ], "pmid": "" }, { "name": "negative regulation of salivary gland boundary specification", "id": "GO:0045705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045705", "evidence": [ { "database": "UniProtKB", "id": "A1Z8F4", "url": "https://www.uniprot.org/uniprotkb/A1Z8F4" } ], "pmid": "" }, { "name": "wing disc dorsal/ventral pattern formation", "id": "GO:0048190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048190", "evidence": [ { "database": "UniProtKB", "id": "A1Z8F4", "url": "https://www.uniprot.org/uniprotkb/A1Z8F4" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A1Z8F4", "url": "https://www.uniprot.org/uniprotkb/A1Z8F4" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A1Z8F4", "url": "https://www.uniprot.org/uniprotkb/A1Z8F4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1Z8F4-1", "start_pos": "1060", "end_pos": "1060", "site_lbl": "Thr1060", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1060, "start_aa": "Thr", "end_pos": 1060, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1060", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A1Z8F4-1", "start_pos": "1062", "end_pos": "1062", "site_lbl": "Thr1062", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1062, "start_aa": "Thr", "end_pos": 1062, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1062", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A1Z8F4-1", "start_pos": "1514", "end_pos": "1514", "site_lbl": "Thr1514", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1514, "start_aa": "Thr", "end_pos": 1514, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1514", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A1Z8F4-1", "start_pos": "823", "end_pos": "823", "site_lbl": "Thr823", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 823, "start_aa": "Thr", "end_pos": 823, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr823", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A1Z8F4-1", "start_pos": "517", "end_pos": "517", "site_lbl": "Cys517", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Results in ectopic venation of developing wings; when associated with 486-S--S-489. Phenotype is more severe when also associated with 1834-N--N-1838 and 1846-S--S-1849.", "evidence": [ { "database": "UniProtKB", "id": "A1Z8F4", "url": "https://www.uniprot.org/uniprotkb/A1Z8F4" }, { "database": "PubMed", "id": "38344065", "url": "https://glygen.org/publication/PubMed/38344065" } ] } ] } ], "record_id": "A1Z8F4-1" }, { "uniprot_canonical_ac": "Q9W2Z7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W2Z7", "url": "https://www.uniprot.org/uniprotkb/Q9W2Z7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 364, "chemical_mass": 38031.0, "gene_names": "CG12634;CG12649;CG18512;Dmel\\CG32694;BcDNA:RE02049;CG12634;CG12649;CG18512;CG32694;Dmel\\CG32694;Dmel_CG32694", "protein_name": "Cell wall protein DAN4", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9W2Z7-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Thr126", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 126, "start_aa": "Thr", "end_pos": 126, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr126", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9W2Z7-1" }, { "uniprot_canonical_ac": "Q9VRW2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VRW2", "url": "https://www.uniprot.org/uniprotkb/Q9VRW2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1320, "chemical_mass": 146536.0, "gene_names": "AMT;Dmel\\CG10226;AMT;CG10226;DmCG10226;Dmel\\CG10226;Dmel_CG10226", "protein_name": "Multidrug resistance protein homolog 65", "disease": [ { "disease_id": "DOID:0050848", "name": "obstructive sleep apnea", "description": "A sleep apnea that is characterized by repeated collapse and obstruction of the upper airway during sleep, which results in reduced airflow (hypopnea) or complete airflow cessation (apnea), oxygen desaturation, and arousals from sleep.", "url": "https://disease-ontology.org/term/DOID:0050848", "evidence": [ { "id": "0050848", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050848" } ], "weight": 0.0 }, { "disease_id": "DOID:0050861", "name": "colorectal adenocarcinoma", "description": "A colorectal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:0050861", "evidence": [ { "id": "0050861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050861" } ], "weight": 0.0 }, { "disease_id": "DOID:0060643", "name": "primary sclerosing cholangitis", "description": "A sclerosing cholangitis characterized by fibroobliterative inflammation of the biliary tract, leading to cirrhosis and portal hypertension.", "url": "https://disease-ontology.org/term/DOID:0060643", "evidence": [ { "id": "0060643", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060643" } ], "weight": 0.0 }, { "disease_id": "DOID:0060750", "name": "familial temporal lobe epilepsy 3", "description": "A temporal lobe epilepsy characterized by simple or complex partial seizures often accompanied by intense feelings of deja or altered awareness and that has_material_basis_in variation in the chromosome region 4q13.2-q21.3.", "url": "https://disease-ontology.org/term/DOID:0060750", "evidence": [ { "id": "0060750", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060750" } ], "weight": 0.0 }, { "disease_id": "DOID:0070223", "name": "progressive familial intrahepatic cholestasis 3", "description": "A progressive familial intrahepatic cholestasis characterized by autosomal recessive inheritance of intrahepatic cholestasis and elevated serum GGT1 activity that has_material_basis_in mutation in the ABCB4 gene on chromosome 7q21.12.", "url": "https://disease-ontology.org/term/DOID:0070223", "evidence": [ { "id": "0070223", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070223" } ], "weight": 0.0 }, { "disease_id": "DOID:0070229", "name": "intrahepatic cholestasis of pregnancy 3", "description": "An intrahepatic cholestasis of pregnancy characterized by autosomal dominant inheritance that has_material_basis_in mutation in the ABCB4 gene on chromosome 7q21.", "url": "https://disease-ontology.org/term/DOID:0070229", "evidence": [ { "id": "0070229", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070229" } ], "weight": 0.0 }, { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 }, { "disease_id": "DOID:0080797", "name": "nasal type extranodal NK/T-cell lymphoma", "description": "A mature T-cell and NK-cell lymphoma that is characterized by an often angiocentric and angiodestructive cellular infiltrate composed of EBV positive NK/T cells.", "url": "https://disease-ontology.org/term/DOID:0080797", "evidence": [ { "id": "0080797", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080797" } ], "weight": 0.0 }, { "disease_id": "DOID:0110893", "name": "inflammatory bowel disease 13", "description": "An inflammatory bowel disease that has_material_basis_in variation in the ABCB1 gene on chromosome 7q21.1.", "url": "https://disease-ontology.org/term/DOID:0110893", "evidence": [ { "id": "0110893", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110893" } ], "weight": 0.0 }, { "disease_id": "DOID:10159", "name": "osteonecrosis", "description": "An ischemic bone disease that results_in necrosis located_in bone.", "url": "https://disease-ontology.org/term/DOID:10159", "evidence": [ { "id": "10159", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10159" } ], "weight": 0.0 }, { "disease_id": "DOID:10939", "name": "antisocial personality disorder", "description": "A personality disorder that involves a pervasive pattern of disregard for, and violation of, the rights of others that begins in childhood or early adolescence and continues into adulthood.", "url": "https://disease-ontology.org/term/DOID:10939", "evidence": [ { "id": "10939", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10939" } ], "weight": 0.0 }, { "disease_id": "DOID:1168", "name": "familial hyperlipidemia", "description": "A lipid metabolism disease that is characterized by elevated levels of lipids in the blood.", "url": "https://disease-ontology.org/term/DOID:1168", "evidence": [ { "id": "1168", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1168" } ], "weight": 0.0 }, { "disease_id": "DOID:12236", "name": "primary biliary cholangitis", "description": "A liver cirrhosis characterized by chronic and slow progressive destruction of intrahepatic bile ducts.", "url": "https://disease-ontology.org/term/DOID:12236", "evidence": [ { "id": "12236", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12236" } ], "weight": 0.0 }, { "disease_id": "DOID:12365", "name": "malaria", "description": "A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle.", "url": "https://disease-ontology.org/term/DOID:12365", "evidence": [ { "id": "12365", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12365" } ], "weight": 0.0 }, { "disease_id": "DOID:13241", "name": "Behcet's disease", "description": "An autoimmune disease that is characterized by mucocutaneous manifestations, including recurrent oral and genital ulcerations, ocular manifestations, especially chronic relapsing uveitis, and systemic vasculitis involving arteries and veins of all sizes.", "url": "https://disease-ontology.org/term/DOID:13241", "evidence": [ { "id": "13241", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13241" } ], "weight": 0.0 }, { "disease_id": "DOID:13413", "name": "hepatic encephalopathy", "description": "A brain disease that is characterized by loss of brain function, the occurrence of confusion, altered level of consciousness, and coma that results when the liver is unable to remove toxins from the blood.", "url": "https://disease-ontology.org/term/DOID:13413", "evidence": [ { "id": "13413", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13413" } ], "weight": 0.0 }, { "disease_id": "DOID:13580", "name": "cholestasis", "description": "A bile duct disease that is characterized by where bile cannot flow from the liver to the duodenum.", "url": "https://disease-ontology.org/term/DOID:13580", "evidence": [ { "id": "13580", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13580" } ], "weight": 0.0 }, { "disease_id": "DOID:1485", "name": "cystic fibrosis", "description": "A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs.", "url": "https://disease-ontology.org/term/DOID:1485", "evidence": [ { "id": "1485", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1485" } ], "weight": 0.0 }, { "disease_id": "DOID:1824", "name": "status epilepticus", "description": "", "url": "https://disease-ontology.org/term/DOID:1824", "evidence": [ { "id": "1824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1824" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:1849", "name": "cannabis dependence", "description": "A drug dependence that involves the continued use of cannabis despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:1849", "evidence": [ { "id": "1849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1849" } ], "weight": 0.0 }, { "disease_id": "DOID:1852", "name": "intrahepatic cholestasis", "description": "A cholestasis characterized by impairment of the bile flow caused by obstruction located_in liver.", "url": "https://disease-ontology.org/term/DOID:1852", "evidence": [ { "id": "1852", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1852" } ], "weight": 0.0 }, { "disease_id": "DOID:1949", "name": "cholecystitis", "description": "A cholangitis that is characterized by an inflammation that is located in the gallbladder.", "url": "https://disease-ontology.org/term/DOID:1949", "evidence": [ { "id": "1949", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1949" } ], "weight": 0.0 }, { "disease_id": "DOID:2154", "name": "nephroblastoma", "description": "A kidney cancer that affects the kidneys and typically occuring in children.", "url": "https://disease-ontology.org/term/DOID:2154", "evidence": [ { "id": "2154", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2154" } ], "weight": 0.0 }, { "disease_id": "DOID:2316", "name": "brain ischemia", "description": "An ischemia that is characterized by insufficient blood flow to the brain to meet metabolic demand.", "url": "https://disease-ontology.org/term/DOID:2316", "evidence": [ { "id": "2316", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2316" } ], "weight": 0.0 }, { "disease_id": "DOID:2394", "name": "ovarian cancer", "description": "A female reproductive organ cancer that is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:2394", "evidence": [ { "id": "2394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2394" } ], "weight": 0.0 }, { "disease_id": "DOID:2559", "name": "opiate dependence", "description": "A drug dependence that involves the continued use of opiate drugs despite despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:2559", "evidence": [ { "id": "2559", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2559" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:2917", "name": "cryoglobulinemia", "description": "A hypersensitivity reaction type IV disease that involves large amounts of cryoglobulins in the blood which become thick or gel-like in cold temperatures.", "url": "https://disease-ontology.org/term/DOID:2917", "evidence": [ { "id": "2917", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2917" } ], "weight": 0.0 }, { "disease_id": "DOID:2957", "name": "pulmonary tuberculosis", "description": "A tuberculosis that is a contagious disease located_in lungs. The infection has_symptom fever, has_symptom cough, has_symptom difficulty in breathing, has_symptom inflammatory infiltrations, has_symptom formation of tubercles, has_symptom caseation, has_symptom pleural effusion, and has_symptom fibrosis.", "url": "https://disease-ontology.org/term/DOID:2957", "evidence": [ { "id": "2957", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2957" } ], "weight": 0.0 }, { "disease_id": "DOID:2987", "name": "familial Mediterranean fever", "description": "An autoinflammatory disease characterized by recurrent episodes of fever and acute inflammation of the membranes lining the abdomen, joints and lungs; that has_material_basis_in mutations in the MEFV gene, which encodes the protein pyrin.", "url": "https://disease-ontology.org/term/DOID:2987", "evidence": [ { "id": "2987", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2987" } ], "weight": 0.0 }, { "disease_id": "DOID:3008", "name": "invasive ductal carcinoma", "description": "A breast ductal carcinoma that is characterized by infiltration into the fibrous or fatty tissue of the breast outside of the duct where it originated.", "url": "https://disease-ontology.org/term/DOID:3008", "evidence": [ { "id": "3008", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3008" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 }, { "disease_id": "DOID:3328", "name": "temporal lobe epilepsy", "description": "A focal epilepsy that is characterized by recurrent, unprovoked focal seizures that originate in the temporal lobe of the brain and last about one or two minutes.", "url": "https://disease-ontology.org/term/DOID:3328", "evidence": [ { "id": "3328", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3328" } ], "weight": 0.0 }, { "disease_id": "DOID:3602", "name": "toxic encephalopathy", "description": "A nervous system disease that results from exposure to neurotoxicants and is characterized by an altered mental status, memory loss, and visual problems.", "url": "https://disease-ontology.org/term/DOID:3602", "evidence": [ { "id": "3602", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3602" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:4481", "name": "allergic rhinitis", "description": "A rhinitis that is an allergic inflammation and irritation of the nasal airways involving sneezing, runny nose, nasal congestion, itching and tearing of the eyes caused by exposure to an allergen such as pollen, dust, mold, animal dander and droppings of cockroaches or house dust mites.", "url": "https://disease-ontology.org/term/DOID:4481", "evidence": [ { "id": "4481", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4481" } ], "weight": 0.0 }, { "disease_id": "DOID:5082", "name": "liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:5082", "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ], "weight": 0.0 }, { "disease_id": "DOID:526", "name": "human immunodeficiency virus infectious disease", "description": "A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.", "url": "https://disease-ontology.org/term/DOID:526", "evidence": [ { "id": "526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:526" } ], "weight": 0.0 }, { "disease_id": "DOID:635", "name": "acquired immunodeficiency syndrome", "description": "A Human immunodeficiency virus infectious disease that results_in reduction in the numbers of CD4-bearing helper T cells below 200 per microliter of blood or 14% of all lymphocytes thereby rendering the subject highly vulnerable to life-threatening infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted_by sexual contact, transmitted_by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted_by congenital method, and transmitted_by contaminated needles. Opportunistic infections are common in people with AIDS.", "url": "https://disease-ontology.org/term/DOID:635", "evidence": [ { "id": "635", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:635" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 }, { "disease_id": "DOID:8552", "name": "chronic myeloid leukemia", "description": "A myeloid leukemia that is characterized by over production of white blood cells.", "url": "https://disease-ontology.org/term/DOID:8552", "evidence": [ { "id": "8552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8552" } ], "weight": 0.0 }, { "disease_id": "DOID:8577", "name": "ulcerative colitis", "description": "A colitis that is predominantly confined to the mucosa located_in colon and includes characteristic ulcers, or open sores.", "url": "https://disease-ontology.org/term/DOID:8577", "evidence": [ { "id": "8577", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8577" } ], "weight": 0.0 }, { "disease_id": "DOID:8778", "name": "Crohn's disease", "description": "An intestinal disease that involves inflammation located_in intestine.", "url": "https://disease-ontology.org/term/DOID:8778", "evidence": [ { "id": "8778", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8778" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 }, { "disease_id": "DOID:9974", "name": "drug dependence", "description": "A substance dependence that involves the continued use of drugs despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:9974", "evidence": [ { "id": "9974", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9974" } ], "weight": 0.0 }, { "disease_id": "DOID:9976", "name": "heroin dependence", "description": "An opiate dependence that involves the continued use of heroin despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:9976", "evidence": [ { "id": "9976", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9976" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW2", "url": "https://www.uniprot.org/uniprotkb/Q9VRW2" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW2", "url": "https://www.uniprot.org/uniprotkb/Q9VRW2" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW2", "url": "https://www.uniprot.org/uniprotkb/Q9VRW2" } ], "pmid": "" }, { "name": "ATPase-coupled transmembrane transporter activity", "id": "GO:0042626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042626", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW2", "url": "https://www.uniprot.org/uniprotkb/Q9VRW2" } ], "pmid": "" }, { "name": "ABC-type xenobiotic transporter activity", "id": "GO:0008559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008559", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW2", "url": "https://www.uniprot.org/uniprotkb/Q9VRW2" } ], "pmid": "" }, { "name": "efflux transmembrane transporter activity", "id": "GO:0015562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015562", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW2", "url": "https://www.uniprot.org/uniprotkb/Q9VRW2" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW2", "url": "https://www.uniprot.org/uniprotkb/Q9VRW2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW2", "url": "https://www.uniprot.org/uniprotkb/Q9VRW2" } ], "pmid": "" }, { "name": "ATP-binding cassette (ABC) transporter complex", "id": "GO:0043190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043190", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW2", "url": "https://www.uniprot.org/uniprotkb/Q9VRW2" } ], "pmid": "" } ], "biological_process": [ { "name": "response to toxic substance", "id": "GO:0009636", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009636", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW2", "url": "https://www.uniprot.org/uniprotkb/Q9VRW2" } ], "pmid": "" }, { "name": "renal tubular secretion", "id": "GO:0097254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097254", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW2", "url": "https://www.uniprot.org/uniprotkb/Q9VRW2" } ], "pmid": "" }, { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW2", "url": "https://www.uniprot.org/uniprotkb/Q9VRW2" } ], "pmid": "" }, { "name": "xenobiotic transport", "id": "GO:0042908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042908", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW2", "url": "https://www.uniprot.org/uniprotkb/Q9VRW2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VRW2-1", "start_pos": "19", "end_pos": "19", "site_lbl": "Thr19", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 19, "start_aa": "Thr", "end_pos": 19, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr19", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VRW2-1" }, { "uniprot_canonical_ac": "X2JE74-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JE74", "url": "https://www.uniprot.org/uniprotkb/X2JE74" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1170, "chemical_mass": 127040.0, "gene_names": "X11L;CG5675;CG5678;Dmel\\CG5675;Dmel_CG5675;Dmint1;Dmint;MINT;Mint;X11-like;X11/Mint;X11Lalpha;X11L;X11;dX11/Mint;dX11Lalpha;dX11L;dX11;x11/Mint;x11Lalpha", "protein_name": "", "disease": [], "biological_process": [ { "name": "compound eye development", "id": "GO:0048749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048749", "evidence": [ { "database": "UniProtKB", "id": "X2JE74", "url": "https://www.uniprot.org/uniprotkb/X2JE74" } ], "pmid": "" }, { "name": "protein localization to membrane", "id": "GO:0072657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072657", "evidence": [ { "database": "UniProtKB", "id": "X2JE74", "url": "https://www.uniprot.org/uniprotkb/X2JE74" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "X2JE74", "url": "https://www.uniprot.org/uniprotkb/X2JE74" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "X2JE74", "url": "https://www.uniprot.org/uniprotkb/X2JE74" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "X2JE74", "url": "https://www.uniprot.org/uniprotkb/X2JE74" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "X2JE74", "url": "https://www.uniprot.org/uniprotkb/X2JE74" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "X2JE74", "url": "https://www.uniprot.org/uniprotkb/X2JE74" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "X2JE74", "url": "https://www.uniprot.org/uniprotkb/X2JE74" } ], "pmid": "" } ], "molecular_function": [ { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "X2JE74", "url": "https://www.uniprot.org/uniprotkb/X2JE74" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "X2JE74-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Thr58", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 58, "start_aa": "Thr", "end_pos": 58, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr58", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "X2JE74-1", "start_pos": "896", "end_pos": "896", "site_lbl": "Thr896", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 896, "start_aa": "Thr", "end_pos": 896, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr896", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "X2JE74-1" }, { "uniprot_canonical_ac": "Q9VW79-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VW79", "url": "https://www.uniprot.org/uniprotkb/Q9VW79" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 126, "chemical_mass": 13832.0, "gene_names": "Dmel\\CG14187;CG14187;Dmel\\CG14187;Dmel_CG14187", "protein_name": "", "disease": [], "biological_process": [ { "name": "chorion-containing eggshell formation", "id": "GO:0007304", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007304", "evidence": [ { "database": "UniProtKB", "id": "Q9VW79", "url": "https://www.uniprot.org/uniprotkb/Q9VW79" } ], "pmid": "" } ], "cellular_component": [ { "name": "egg chorion", "id": "GO:0042600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042600", "evidence": [ { "database": "UniProtKB", "id": "Q9VW79", "url": "https://www.uniprot.org/uniprotkb/Q9VW79" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VW79-1" }, { "uniprot_canonical_ac": "A0A0B4KI34-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 941, "chemical_mass": 98521.0, "gene_names": "cindr;BcDNA:GH03163;CD2AP;CG11316;CG1408;CG31012;Cindir;Cindr;Dmel\\CG31012;Dmel_CG31012;cindr", "protein_name": "", "disease": [ { "disease_id": "DOID:0111999", "name": "immunodeficiency 61", "description": "A B cell deficiency characterized by onset in early childhood of recurrent infections due to an intrinsic defect in the ability of B cells to produce antibodies that has_material_basis_in hemizygous mutation in the SH3KBP1 gene on chromosome Xp22.12.", "url": "https://disease-ontology.org/term/DOID:0111999", "evidence": [ { "id": "0111999", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111999" } ], "weight": 0.0 }, { "disease_id": "DOID:0112245", "name": "focal segmental glomerulosclerosis 3", "description": "A focal segmental glomerulosclerosis that has_material_basis_in loss of function mutation in the CD2AP gene on chromosome 6p12.3.", "url": "https://disease-ontology.org/term/DOID:0112245", "evidence": [ { "id": "0112245", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112245" } ], "weight": 0.0 }, { "disease_id": "DOID:1184", "name": "nephrotic syndrome", "description": "A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.", "url": "https://disease-ontology.org/term/DOID:1184", "evidence": [ { "id": "1184", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1184" } ], "weight": 0.0 }, { "disease_id": "DOID:1312", "name": "focal segmental glomerulosclerosis", "description": "", "url": "https://disease-ontology.org/term/DOID:1312", "evidence": [ { "id": "1312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1312" } ], "weight": 0.0 }, { "disease_id": "DOID:680", "name": "tauopathy", "description": "A neurodegenerative disease that has_material_basis_in the pathological aggregation of tau protein in so-called neurofibrillary tangles (NFT) in the human brain.", "url": "https://disease-ontology.org/term/DOID:680", "evidence": [ { "id": "680", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:680" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 } ], "biological_process": [ { "name": "compound eye development", "id": "GO:0048749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048749", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "intercellular bridge organization", "id": "GO:0043063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043063", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "positive regulation of receptor-mediated endocytosis", "id": "GO:0048260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048260", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "regulation of cytokinesis", "id": "GO:0032465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032465", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "border follicle cell migration", "id": "GO:0007298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007298", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "adherens junction assembly", "id": "GO:0034333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034333", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "compound eye morphogenesis", "id": "GO:0001745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001745", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" } ], "molecular_function": [ { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "GTPase activating protein binding", "id": "GO:0032794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032794", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" } ], "cellular_component": [ { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "intercellular bridge", "id": "GO:0045171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045171", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "cleavage furrow", "id": "GO:0032154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032154", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "apical cortex", "id": "GO:0045179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045179", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4KI34-1" }, { "uniprot_canonical_ac": "A8JQY2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JQY2", "url": "https://www.uniprot.org/uniprotkb/A8JQY2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 581, "chemical_mass": 63256.0, "gene_names": "Dmel\\CG12213;anon-87Ab;3;87A7-9/3;CG12213;Dmel\\CG12213;Dmel_CG12213;anon-87Ab", "protein_name": "Golgi integral membrane protein 4", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8JQY2-1" }, { "uniprot_canonical_ac": "A0A0B4K6X8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6X8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6X8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 323, "chemical_mass": 34463.0, "gene_names": "Dmel\\CG11693;CG11693;Dmel\\CG11693;Dmel_CG11693", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4K6X8-1" }, { "uniprot_canonical_ac": "A0A0B4KF34-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF34" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 835, "chemical_mass": 94174.0, "gene_names": "CG12167;CG12167;CG12168;CG31550;Dmel\\CG31550;Dmel_CG31550", "protein_name": "G-patch domain-containing protein", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF34" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF34" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF34" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF34" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF34" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4KF34-1", "start_pos": "392", "end_pos": "392", "site_lbl": "Thr392", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 392, "start_aa": "Thr", "end_pos": 392, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr392", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A0A0B4KF34-1" }, { "uniprot_canonical_ac": "X2JF48-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JF48", "url": "https://www.uniprot.org/uniprotkb/X2JF48" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 923, "chemical_mass": 105076.0, "gene_names": "Dmel\\CG6324;CG6324;Dmel\\CG6324;Dmel_CG6324", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "X2JF48", "url": "https://www.uniprot.org/uniprotkb/X2JF48" } ], "pmid": "" } ], "biological_process": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "X2JF48", "url": "https://www.uniprot.org/uniprotkb/X2JF48" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "X2JF48-1" }, { "uniprot_canonical_ac": "Q9VWP5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWP5", "url": "https://www.uniprot.org/uniprotkb/Q9VWP5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2486, "chemical_mass": 259465.0, "gene_names": "htk;ARID4B;CG34422;CG7274;CG7282;Dmel\\CG34422;Dmel_CG34422;Htk;Q9VWP3_DROME;htk", "protein_name": "", "disease": [ { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP5", "url": "https://www.uniprot.org/uniprotkb/Q9VWP5" } ], "pmid": "" }, { "name": "Sin3-type complex", "id": "GO:0070822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070822", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP5", "url": "https://www.uniprot.org/uniprotkb/Q9VWP5" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP5", "url": "https://www.uniprot.org/uniprotkb/Q9VWP5" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP5", "url": "https://www.uniprot.org/uniprotkb/Q9VWP5" } ], "pmid": "" }, { "name": "transcription coregulator binding", "id": "GO:0001221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001221", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP5", "url": "https://www.uniprot.org/uniprotkb/Q9VWP5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP5", "url": "https://www.uniprot.org/uniprotkb/Q9VWP5" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP5", "url": "https://www.uniprot.org/uniprotkb/Q9VWP5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP5", "url": "https://www.uniprot.org/uniprotkb/Q9VWP5" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP5", "url": "https://www.uniprot.org/uniprotkb/Q9VWP5" } ], "pmid": "" }, { "name": "positive regulation of Notch signaling pathway", "id": "GO:0045747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045747", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP5", "url": "https://www.uniprot.org/uniprotkb/Q9VWP5" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP5", "url": "https://www.uniprot.org/uniprotkb/Q9VWP5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VWP5-1", "start_pos": "1310", "end_pos": "1310", "site_lbl": "Thr1310", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1310, "start_aa": "Thr", "end_pos": 1310, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1310", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VWP5-1", "start_pos": "1407", "end_pos": "1407", "site_lbl": "Thr1407", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1407, "start_aa": "Thr", "end_pos": 1407, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1407", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VWP5-1", "start_pos": "1608", "end_pos": "1608", "site_lbl": "Thr1608", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1608, "start_aa": "Thr", "end_pos": 1608, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1608", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VWP5-1", "start_pos": "1620", "end_pos": "1620", "site_lbl": "Thr1620", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1620, "start_aa": "Thr", "end_pos": 1620, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1620", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VWP5-1", "start_pos": "1953", "end_pos": "1953", "site_lbl": "Thr1953", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1953, "start_aa": "Thr", "end_pos": 1953, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1953", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VWP5-1", "start_pos": "2112", "end_pos": "2112", "site_lbl": "Thr2112", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2112, "start_aa": "Thr", "end_pos": 2112, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2112", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VWP5-1", "start_pos": "456", "end_pos": "456", "site_lbl": "Thr456", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 456, "start_aa": "Thr", "end_pos": 456, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr456", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VWP5-1", "start_pos": "844", "end_pos": "844", "site_lbl": "Thr844", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 844, "start_aa": "Thr", "end_pos": 844, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr844", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VWP5-1" }, { "uniprot_canonical_ac": "Q9VYL1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VYL1", "url": "https://www.uniprot.org/uniprotkb/Q9VYL1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 572, "chemical_mass": 64317.0, "gene_names": "Fpgs1;CG2543;Dmel\\CG2543;Dmel_CG2543;Fpgs1;Fpgs", "protein_name": "Folylpolyglutamate synthase", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VYL1", "url": "https://www.uniprot.org/uniprotkb/Q9VYL1" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VYL1", "url": "https://www.uniprot.org/uniprotkb/Q9VYL1" } ], "pmid": "" }, { "name": "tetrahydrofolylpolyglutamate synthase activity", "id": "GO:0004326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004326", "evidence": [ { "database": "UniProtKB", "id": "Q9VYL1", "url": "https://www.uniprot.org/uniprotkb/Q9VYL1" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q9VYL1", "url": "https://www.uniprot.org/uniprotkb/Q9VYL1" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q9VYL1", "url": "https://www.uniprot.org/uniprotkb/Q9VYL1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VYL1", "url": "https://www.uniprot.org/uniprotkb/Q9VYL1" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VYL1", "url": "https://www.uniprot.org/uniprotkb/Q9VYL1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VYL1", "url": "https://www.uniprot.org/uniprotkb/Q9VYL1" } ], "pmid": "" } ], "biological_process": [ { "name": "one-carbon metabolic process", "id": "GO:0006730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006730", "evidence": [ { "database": "UniProtKB", "id": "Q9VYL1", "url": "https://www.uniprot.org/uniprotkb/Q9VYL1" } ], "pmid": "" }, { "name": "tetrahydrofolylpolyglutamate biosynthetic process", "id": "GO:0046901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046901", "evidence": [ { "database": "UniProtKB", "id": "Q9VYL1", "url": "https://www.uniprot.org/uniprotkb/Q9VYL1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VYL1-1" }, { "uniprot_canonical_ac": "Q9W398-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W398", "url": "https://www.uniprot.org/uniprotkb/Q9W398" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 146, "chemical_mass": 16119.0, "gene_names": "CG15366;CG7267;CG15366;CG44325;CG7267;Dmel\\CG44325;Dmel_CG44325", "protein_name": "", "disease": [], "biological_process": [ { "name": "septate junction assembly", "id": "GO:0019991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019991", "evidence": [ { "database": "UniProtKB", "id": "Q9W398", "url": "https://www.uniprot.org/uniprotkb/Q9W398" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9W398", "url": "https://www.uniprot.org/uniprotkb/Q9W398" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W398-1" }, { "uniprot_canonical_ac": "A8DZ29-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8DZ29", "url": "https://www.uniprot.org/uniprotkb/A8DZ29" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1919, "chemical_mass": 211123.0, "gene_names": "eIF4G1;CG10811;Dmel\\CG10811;Dmel_CG10811;EIF4G1;EIF4G;Eif4G;deIF4G;eIF-4G;eIF4G1;eIF4G;eIF4g;eiF-4G;p200", "protein_name": "", "disease": [ { "disease_id": "DOID:0060892", "name": "late onset Parkinson's disease", "description": "A Parkinson's disease characterized by onset of motor symptoms typically after 60 years of age.", "url": "https://disease-ontology.org/term/DOID:0060892", "evidence": [ { "id": "0060892", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060892" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 } ], "biological_process": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "A8DZ29", "url": "https://www.uniprot.org/uniprotkb/A8DZ29" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A8DZ29", "url": "https://www.uniprot.org/uniprotkb/A8DZ29" } ], "pmid": "" }, { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "A8DZ29", "url": "https://www.uniprot.org/uniprotkb/A8DZ29" } ], "pmid": "" }, { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A8DZ29", "url": "https://www.uniprot.org/uniprotkb/A8DZ29" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A8DZ29", "url": "https://www.uniprot.org/uniprotkb/A8DZ29" } ], "pmid": "" }, { "name": "eukaryotic initiation factor 4E binding", "id": "GO:0008190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008190", "evidence": [ { "database": "UniProtKB", "id": "A8DZ29", "url": "https://www.uniprot.org/uniprotkb/A8DZ29" } ], "pmid": "" }, { "name": "RNA 7-methylguanosine cap binding", "id": "GO:0000340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000340", "evidence": [ { "database": "UniProtKB", "id": "A8DZ29", "url": "https://www.uniprot.org/uniprotkb/A8DZ29" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "A8DZ29", "url": "https://www.uniprot.org/uniprotkb/A8DZ29" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A8DZ29", "url": "https://www.uniprot.org/uniprotkb/A8DZ29" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A8DZ29", "url": "https://www.uniprot.org/uniprotkb/A8DZ29" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 4F complex", "id": "GO:0016281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016281", "evidence": [ { "database": "UniProtKB", "id": "A8DZ29", "url": "https://www.uniprot.org/uniprotkb/A8DZ29" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A8DZ29-1", "start_pos": "1412", "end_pos": "1412", "site_lbl": "Thr1412", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1412, "start_aa": "Thr", "end_pos": 1412, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1412", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A8DZ29-1", "start_pos": "1414", "end_pos": "1414", "site_lbl": "Thr1414", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1414, "start_aa": "Thr", "end_pos": 1414, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1414", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A8DZ29-1", "start_pos": "539", "end_pos": "539", "site_lbl": "Ser539", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 539, "start_aa": "Ser", "end_pos": 539, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser539", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A8DZ29", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A8DZ29" } ] } ] }, { "uniprot_canonical_ac": "A8DZ29-1", "start_pos": "562", "end_pos": "562", "site_lbl": "Ser562", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 562, "start_aa": "Ser", "end_pos": 562, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser562", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A8DZ29", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A8DZ29" } ] } ] }, { "uniprot_canonical_ac": "A8DZ29-1", "start_pos": "564", "end_pos": "564", "site_lbl": "Thr564", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 564, "start_aa": "Thr", "end_pos": 564, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr564", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A8DZ29", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A8DZ29" } ] } ] }, { "uniprot_canonical_ac": "A8DZ29-1", "start_pos": "569", "end_pos": "569", "site_lbl": "Thr569", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 569, "start_aa": "Thr", "end_pos": 569, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr569", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A8DZ29-1", "start_pos": "586", "end_pos": "586", "site_lbl": "Thr586", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 586, "start_aa": "Thr", "end_pos": 586, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr586", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A8DZ29-1", "start_pos": "624", "end_pos": "624", "site_lbl": "Ser624", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 624, "start_aa": "Ser", "end_pos": 624, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser624", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A8DZ29", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A8DZ29" } ] } ] }, { "uniprot_canonical_ac": "A8DZ29-1", "start_pos": "715", "end_pos": "715", "site_lbl": "Thr715", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 715, "start_aa": "Thr", "end_pos": 715, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr715", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A8DZ29-1" }, { "uniprot_canonical_ac": "A0A6F7R657-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 709, "chemical_mass": 79477.0, "gene_names": "wdb;0318/07;07;B56-2;BEST:LD02456;BcDNA:LD34343;CG5643;Dmel\\CG5643;Dmel_CG5643;EP3559;LD02456;PP2-AB;PP2A-B';PP2A[B'-2];PP2A;PP2a;WDB;Wdb;Widerborst;dB56-2;dPP2A-B56-2;dPP2A;l(3)S031807;wbd;wdb", "protein_name": "", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of smoothened signaling pathway", "id": "GO:0045880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045880", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "negative regulation of insulin receptor signaling pathway", "id": "GO:0046627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046627", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "negative regulation of lipid storage", "id": "GO:0010888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010888", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "positive regulation of macroautophagy", "id": "GO:0016239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016239", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051898", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "spindle assembly", "id": "GO:0051225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051225", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "determination of adult lifespan", "id": "GO:0008340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008340", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "negative regulation of smoothened signaling pathway", "id": "GO:0045879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045879", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "negative regulation of hippo signaling", "id": "GO:0035331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035331", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "meiotic spindle assembly", "id": "GO:0090306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090306", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "maintenance of sister chromatid cohesion", "id": "GO:0034086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034086", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "protein phosphatase type 2A complex", "id": "GO:0000159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000159", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein phosphatase regulator activity", "id": "GO:0019888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019888", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "protein phosphatase activator activity", "id": "GO:0072542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072542", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A6F7R657-1" }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2238, "chemical_mass": 255301.0, "gene_names": "brp;BRP;Brp;Bruchpilot;CG12932;CG12933;CG1931;CG30336;CG30337;CG34146;CG42344;Cast;Dmel\\CG42344;Dmel_CG42344;MAbnc82;Mabnc82;NC82;Nc82;brp;mAb nc82;mAbnc82;nc-82;nc82", "protein_name": "Protein bruchpilot", "disease": [], "biological_process": [ { "name": "cytoskeletal matrix organization at active zone", "id": "GO:0048789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048789", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "synaptic vesicle clustering", "id": "GO:0097091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097091", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "maintenance of presynaptic active zone structure", "id": "GO:0048790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048790", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "presynaptic active zone organization", "id": "GO:1990709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990709", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "neuromuscular synaptic transmission", "id": "GO:0007274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007274", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "adult locomotory behavior", "id": "GO:0008344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008344", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "short-term memory", "id": "GO:0007614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007614", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "regulation of synaptic plasticity", "id": "GO:0048167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048167", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "neurotransmitter secretion", "id": "GO:0007269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007269", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "regulation of synaptic vesicle fusion to presynaptic active zone membrane", "id": "GO:0031630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031630", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "presynaptic active zone assembly", "id": "GO:1904071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904071", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "synapse maturation", "id": "GO:0060074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060074", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "anesthesia-resistant memory", "id": "GO:0007615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007615", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "synaptic vesicle tethering involved in synaptic vesicle exocytosis", "id": "GO:0099069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099069", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "regulation of calcium-dependent activation of synaptic vesicle fusion", "id": "GO:0150037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150037", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" } ], "cellular_component": [ { "name": "presynaptic active zone cytoplasmic component", "id": "GO:0098831", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098831", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "axon terminus", "id": "GO:0043679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043679", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "presynaptic active zone", "id": "GO:0048786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048786", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "cytoskeleton of presynaptic active zone", "id": "GO:0048788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048788", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "T-bar", "id": "GO:0098986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098986", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "synaptic vesicle, readily releasable pool", "id": "GO:1990474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990474", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of presynaptic active zone", "id": "GO:0098882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098882", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Thr151", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 151, "start_aa": "Thr", "end_pos": 151, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr151", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "1677", "end_pos": "1677", "site_lbl": "Thr1677", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1677, "start_aa": "Thr", "end_pos": 1677, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1677", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A0A0B4K7K9", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A0B4K7K9" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "569", "end_pos": "569", "site_lbl": "Thr569", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 569, "start_aa": "Thr", "end_pos": 569, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr569", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A0A0B4K7K9", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A0B4K7K9" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "1028", "end_pos": "1028", "site_lbl": "Ser1028", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "1080", "end_pos": "1080", "site_lbl": "Thr1080", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "1081", "end_pos": "1081", "site_lbl": "Ser1081", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Ser114", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Ser118", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "130", "end_pos": "130", "site_lbl": "Tyr130", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Ser133", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "137", "end_pos": "137", "site_lbl": "Ser137", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "139", "end_pos": "139", "site_lbl": "Ser139", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "1666", "end_pos": "1666", "site_lbl": "Ser1666", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "1668", "end_pos": "1668", "site_lbl": "Ser1668", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "1679", "end_pos": "1679", "site_lbl": "Ser1679", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "1681", "end_pos": "1681", "site_lbl": "Ser1681", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Ser16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "1854", "end_pos": "1854", "site_lbl": "Ser1854", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "187", "end_pos": "187", "site_lbl": "Ser187", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "188", "end_pos": "188", "site_lbl": "Ser188", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "197", "end_pos": "197", "site_lbl": "Ser197", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Ser32", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "34", "end_pos": "34", "site_lbl": "Ser34", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Ser43", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "59", "end_pos": "59", "site_lbl": "Thr59", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "60", "end_pos": "60", "site_lbl": "Ser60", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "71", "end_pos": "71", "site_lbl": "Ser71", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Ser73", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "90", "end_pos": "90", "site_lbl": "Ser90", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Reduced hatching rate and disturbed axonal transport of active zone proteins; when associated with 71-A--A-73.", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "924", "end_pos": "924", "site_lbl": "Ser924", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "925", "end_pos": "925", "site_lbl": "Ser925", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "926", "end_pos": "926", "site_lbl": "Ser926", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] } ], "record_id": "A0A0B4K7K9-1" }, { "uniprot_canonical_ac": "A1ZBJ6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZBJ6", "url": "https://www.uniprot.org/uniprotkb/A1ZBJ6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1379, "chemical_mass": 147988.0, "gene_names": "Rgk1;CG30127;CG44011;CG9811;CT27512;Dmel\\CG44011;Dmel_CG44011;RGK1;Rgk1;rgk1", "protein_name": "", "disease": [], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A1ZBJ6", "url": "https://www.uniprot.org/uniprotkb/A1ZBJ6" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A1ZBJ6", "url": "https://www.uniprot.org/uniprotkb/A1ZBJ6" } ], "pmid": "" }, { "name": "calcium channel regulator activity", "id": "GO:0005246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005246", "evidence": [ { "database": "UniProtKB", "id": "A1ZBJ6", "url": "https://www.uniprot.org/uniprotkb/A1ZBJ6" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A1ZBJ6", "url": "https://www.uniprot.org/uniprotkb/A1ZBJ6" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "A1ZBJ6", "url": "https://www.uniprot.org/uniprotkb/A1ZBJ6" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A1ZBJ6", "url": "https://www.uniprot.org/uniprotkb/A1ZBJ6" } ], "pmid": "" } ], "biological_process": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A1ZBJ6", "url": "https://www.uniprot.org/uniprotkb/A1ZBJ6" } ], "pmid": "" }, { "name": "anesthesia-resistant memory", "id": "GO:0007615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007615", "evidence": [ { "database": "UniProtKB", "id": "A1ZBJ6", "url": "https://www.uniprot.org/uniprotkb/A1ZBJ6" } ], "pmid": "" }, { "name": "medium-term memory", "id": "GO:0072375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072375", "evidence": [ { "database": "UniProtKB", "id": "A1ZBJ6", "url": "https://www.uniprot.org/uniprotkb/A1ZBJ6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1ZBJ6-1", "start_pos": "838", "end_pos": "838", "site_lbl": "Thr838", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 838, "start_aa": "Thr", "end_pos": 838, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr838", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A1ZBJ6-1" }, { "uniprot_canonical_ac": "A0A0B4LHY5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 728, "chemical_mass": 77510.0, "gene_names": "Lnk;CG 17367;CG17367;CG5908;Dmel\\CG17367;Dmel_CG17367;LNK;Lnk;SH2B;dSH2B;lnk", "protein_name": "", "disease": [ { "disease_id": "DOID:0060398", "name": "chromosome 16p11.2 deletion syndrome, 220-kb", "description": "A chromosomal deletion syndrome that is characterized by developmental delay, mild intellectual disability and autism spectrum disorder and that has_material_basis_in a partial deletion of the short arm of chromosome 16, specifically a deletion of a 220-kb region on chromosome 16p11.2 (chr16:28.73-28.95 Mb) encompassing approximately 9 genes, including the SH2B1 gene.", "url": "https://disease-ontology.org/term/DOID:0060398", "evidence": [ { "id": "0060398", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060398" } ], "weight": 0.0 }, { "disease_id": "DOID:0060652", "name": "familial erythrocytosis 1", "description": "A primary polycythemia that has_material_basis_in mutation in the gene encoding the erythropoietin receptor. It is characterized by increased serum red blood cell mass and hemoglobin concentration, hypersensitivity of erythroid progenitors to EPO, and low serum levels of EPO.", "url": "https://disease-ontology.org/term/DOID:0060652", "evidence": [ { "id": "0060652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060652" } ], "weight": 0.0 }, { "disease_id": "DOID:0080199", "name": "colorectal carcinoma", "description": "A colorectal cancer that arises from the colon or rectum and invades through the muscularis mucosa into the submucosa.", "url": "https://disease-ontology.org/term/DOID:0080199", "evidence": [ { "id": "0080199", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080199" } ], "weight": 0.0 }, { "disease_id": "DOID:2224", "name": "essential thrombocythemia", "description": "A myeloproliferative neoplasm that is characterized by sustained thrombocytosis in the blood, increased numbers of large, mature megakaryocytes in the bone marrow, and episodes of thrombosis and/or hemorrhage and that results_in the overproduction of platelets.", "url": "https://disease-ontology.org/term/DOID:2224", "evidence": [ { "id": "2224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2224" } ], "weight": 0.0 }, { "disease_id": "DOID:4971", "name": "myelofibrosis", "description": "A myeloid neoplasm that is located in the bone marrow which results in bone marrow being replaced by fibrous (scar) tissue.", "url": "https://disease-ontology.org/term/DOID:4971", "evidence": [ { "id": "4971", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4971" } ], "weight": 0.0 }, { "disease_id": "DOID:8552", "name": "chronic myeloid leukemia", "description": "A myeloid leukemia that is characterized by over production of white blood cells.", "url": "https://disease-ontology.org/term/DOID:8552", "evidence": [ { "id": "8552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8552" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.", "url": "https://disease-ontology.org/term/DOID:9744", "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ], "weight": 0.0 } ], "biological_process": [ { "name": "female mating behavior", "id": "GO:0060180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060180", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "regulation of growth", "id": "GO:0040008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040008", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "positive regulation of TORC1 signaling", "id": "GO:1904263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904263", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "carbohydrate homeostasis", "id": "GO:0033500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033500", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "positive regulation of cell growth", "id": "GO:0030307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030307", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051897", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "positive regulation of ERK1 and ERK2 cascade", "id": "GO:0070374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "insulin receptor signaling pathway", "id": "GO:0008286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008286", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "vascular endothelial growth factor receptor signaling pathway", "id": "GO:0048010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048010", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "positive regulation of protein localization to cell cortex", "id": "GO:1904778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904778", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "triglyceride homeostasis", "id": "GO:0070328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070328", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" } ], "molecular_function": [ { "name": "signaling adaptor activity", "id": "GO:0035591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035591", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "transmembrane receptor protein tyrosine kinase adaptor activity", "id": "GO:0005068", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005068", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4LHY5-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Thr22", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 22, "start_aa": "Thr", "end_pos": 22, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr22", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4LHY5-1", "start_pos": "400", "end_pos": "400", "site_lbl": "Thr400", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 400, "start_aa": "Thr", "end_pos": 400, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr400", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A0A0B4LHY5-1" }, { "uniprot_canonical_ac": "X2JCX9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JCX9", "url": "https://www.uniprot.org/uniprotkb/X2JCX9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 218, "chemical_mass": 24511.0, "gene_names": "Ptth;CG13687;Dmel\\CG13687;Dmel_CG13687;PTTH;Ptth;ptth", "protein_name": "", "disease": [], "cellular_component": [ { "name": "varicosity", "id": "GO:0043196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043196", "evidence": [ { "database": "UniProtKB", "id": "X2JCX9", "url": "https://www.uniprot.org/uniprotkb/X2JCX9" } ], "pmid": "" } ], "molecular_function": [ { "name": "prothoracicotrophic hormone activity", "id": "GO:0018445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018445", "evidence": [ { "database": "UniProtKB", "id": "X2JCX9", "url": "https://www.uniprot.org/uniprotkb/X2JCX9" } ], "pmid": "" } ], "biological_process": [ { "name": "negative phototaxis", "id": "GO:0046957", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046957", "evidence": [ { "database": "UniProtKB", "id": "X2JCX9", "url": "https://www.uniprot.org/uniprotkb/X2JCX9" } ], "pmid": "" }, { "name": "metamorphosis", "id": "GO:0007552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007552", "evidence": [ { "database": "UniProtKB", "id": "X2JCX9", "url": "https://www.uniprot.org/uniprotkb/X2JCX9" } ], "pmid": "" }, { "name": "torso signaling pathway", "id": "GO:0008293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008293", "evidence": [ { "database": "UniProtKB", "id": "X2JCX9", "url": "https://www.uniprot.org/uniprotkb/X2JCX9" } ], "pmid": "" }, { "name": "positive regulation of ecdysteroid biosynthetic process", "id": "GO:0045998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045998", "evidence": [ { "database": "UniProtKB", "id": "X2JCX9", "url": "https://www.uniprot.org/uniprotkb/X2JCX9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "X2JCX9-1" }, { "uniprot_canonical_ac": "A0A0B4KFE4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 728, "chemical_mass": 81815.0, "gene_names": "Acsl;4;7447;ACSL1;ACSL3/4;ACSL3;ACS;Acsl;CG8732;Dmel\\CG8732;Dmel_CG8732;FACS;FCS;acsl;anon-WO0172774.173;dAcsl;dFAC;l(2)05847;l(2)44DEa;l(2)7447;l(2)SH0465;l(2)SH2 0465;l(2)k05304", "protein_name": "long-chain-fatty-acid--CoA ligase", "disease": [ { "disease_id": "DOID:0050776", "name": "non-syndromic X-linked intellectual disability", "description": "A non-syndromic intellectual disability characterized by a X-linked inheritance pattern.", "url": "https://disease-ontology.org/term/DOID:0050776", "evidence": [ { "id": "0050776", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050776" } ], "weight": 0.0 }, { "disease_id": "DOID:0112050", "name": "non-syndromic X-linked intellectual disability 63", "description": "A non-syndromic X-linked intellectual disability characterized by moderate to severe nonprogressive intellectual disability in males and moderate intellectual disability to normal intelligence in females that has_material_basis_in heterozygous mutation in the ACSL4 gene on chromosome Xq23.", "url": "https://disease-ontology.org/term/DOID:0112050", "evidence": [ { "id": "0112050", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112050" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:14501", "name": "Sjogren-Larsson syndrome", "description": "A syndrome that is characterized by ichthyosis, mental retardation, spastic paraparesis, macular dystrophy, and leukoencephalopathy, and has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the aldehyde dehydrogenase 3 family member A2 (ALDH3A2) gene, which encodes fatty aldehyde dehydrogenase, on chromosome 17p11.", "url": "https://disease-ontology.org/term/DOID:14501", "evidence": [ { "id": "14501", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14501" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "long-chain fatty acid-CoA ligase activity", "id": "GO:0004467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004467", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "palmitoyl-CoA ligase activity", "id": "GO:0090433", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090433", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" } ], "biological_process": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "segmentation", "id": "GO:0035282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035282", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "positive regulation of triglyceride storage", "id": "GO:0010890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010890", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "long-chain fatty acid metabolic process", "id": "GO:0001676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001676", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "long-chain fatty-acyl-CoA biosynthetic process", "id": "GO:0035338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035338", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "long-chain fatty-acyl-CoA metabolic process", "id": "GO:0035336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035336", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "phosphatidylglycerol biosynthetic process", "id": "GO:0006655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006655", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4KFE4-1" }, { "uniprot_canonical_ac": "A1ZBW0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZBW0", "url": "https://www.uniprot.org/uniprotkb/A1ZBW0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 502, "chemical_mass": 51022.0, "gene_names": "HnRNP-K;BL;Bancal;Bl;CG13425;Dmel\\CG13425;Dmel_CG13425;HnRNP-K;Hrb57A;Q18;bl;dhnRNP K;hnRNP K;hnRNP-A1L;hrb57a;l(2)k08305", "protein_name": "", "disease": [ { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10300", "name": "Raynaud disease", "description": "A peripheral vascular disease that is characterized by bilateral Raynaud phenomenon, the abrupt onset of digital paleness or cyanosis in response to cold exposure or stress.", "url": "https://disease-ontology.org/term/DOID:10300", "evidence": [ { "id": "10300", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10300" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A1ZBW0", "url": "https://www.uniprot.org/uniprotkb/A1ZBW0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A1ZBW0", "url": "https://www.uniprot.org/uniprotkb/A1ZBW0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1ZBW0", "url": "https://www.uniprot.org/uniprotkb/A1ZBW0" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A1ZBW0", "url": "https://www.uniprot.org/uniprotkb/A1ZBW0" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A1ZBW0", "url": "https://www.uniprot.org/uniprotkb/A1ZBW0" } ], "pmid": "" }, { "name": "omega speckle", "id": "GO:0035062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035062", "evidence": [ { "database": "UniProtKB", "id": "A1ZBW0", "url": "https://www.uniprot.org/uniprotkb/A1ZBW0" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "A1ZBW0", "url": "https://www.uniprot.org/uniprotkb/A1ZBW0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A1ZBW0", "url": "https://www.uniprot.org/uniprotkb/A1ZBW0" } ], "pmid": "" }, { "name": "regulation of mRNA splicing, via spliceosome", "id": "GO:0048024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048024", "evidence": [ { "database": "UniProtKB", "id": "A1ZBW0", "url": "https://www.uniprot.org/uniprotkb/A1ZBW0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1ZBW0-1" }, { "uniprot_canonical_ac": "X2JEJ0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JEJ0", "url": "https://www.uniprot.org/uniprotkb/X2JEJ0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 551, "chemical_mass": 62529.0, "gene_names": "Dmel\\CG1440;CG1440;Dmel\\CG1440;Dmel_CG1440", "protein_name": "Bleomycin hydrolase", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "X2JEJ0", "url": "https://www.uniprot.org/uniprotkb/X2JEJ0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "X2JEJ0", "url": "https://www.uniprot.org/uniprotkb/X2JEJ0" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "X2JEJ0", "url": "https://www.uniprot.org/uniprotkb/X2JEJ0" } ], "pmid": "" }, { "name": "response to toxic substance", "id": "GO:0009636", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009636", "evidence": [ { "database": "UniProtKB", "id": "X2JEJ0", "url": "https://www.uniprot.org/uniprotkb/X2JEJ0" } ], "pmid": "" }, { "name": "homocysteine catabolic process", "id": "GO:0043418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043418", "evidence": [ { "database": "UniProtKB", "id": "X2JEJ0", "url": "https://www.uniprot.org/uniprotkb/X2JEJ0" } ], "pmid": "" } ], "molecular_function": [ { "name": "cysteine-type endopeptidase activity", "id": "GO:0004197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004197", "evidence": [ { "database": "UniProtKB", "id": "X2JEJ0", "url": "https://www.uniprot.org/uniprotkb/X2JEJ0" } ], "pmid": "" }, { "name": "cysteine-type aminopeptidase activity", "id": "GO:0070005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070005", "evidence": [ { "database": "UniProtKB", "id": "X2JEJ0", "url": "https://www.uniprot.org/uniprotkb/X2JEJ0" } ], "pmid": "" }, { "name": "aminopeptidase activity", "id": "GO:0004177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004177", "evidence": [ { "database": "UniProtKB", "id": "X2JEJ0", "url": "https://www.uniprot.org/uniprotkb/X2JEJ0" } ], "pmid": "" }, { "name": "cysteine-type peptidase activity", "id": "GO:0008234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008234", "evidence": [ { "database": "UniProtKB", "id": "X2JEJ0", "url": "https://www.uniprot.org/uniprotkb/X2JEJ0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "X2JEJ0-1" }, { "uniprot_canonical_ac": "Q9VYF5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VYF5", "url": "https://www.uniprot.org/uniprotkb/Q9VYF5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 203, "chemical_mass": 23669.0, "gene_names": "Dmel\\CG15742;CG15742;Dmel\\CG15742;Dmel_CG15742", "protein_name": "CG15742-PA", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VYF5-1" }, { "uniprot_canonical_ac": "Q9W2H8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W2H8", "url": "https://www.uniprot.org/uniprotkb/Q9W2H8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1629, "chemical_mass": 183219.0, "gene_names": "Agl;BEST:GH22856;CG9485;Dmel\\CG9485;Dmel_CG9485", "protein_name": "Glycogen debranching enzyme", "disease": [ { "disease_id": "DOID:2748", "name": "glycogen storage disease III", "description": "A glycogen storage disease that is characterized by an accumulation of abnormal glycogen with short outer chains and that has_material_basis_in homozygous or compound heterozygous mutation in the AGL gene, which encodes the glycogen debrancher enzyme, on chromosome 1p21.", "url": "https://disease-ontology.org/term/DOID:2748", "evidence": [ { "id": "2748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2748" } ], "weight": 0.0 }, { "disease_id": "DOID:4676", "name": "uremia", "description": "", "url": "https://disease-ontology.org/term/DOID:4676", "evidence": [ { "id": "4676", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4676" } ], "weight": 0.0 }, { "disease_id": "DOID:5212", "name": "congenital disorder of glycosylation", "description": "A carbohydrate metabolic disorder that involves deficient or defective glycosylation of a variety of tissue proteins and/or lipids.", "url": "https://disease-ontology.org/term/DOID:5212", "evidence": [ { "id": "5212", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5212" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "4-alpha-glucanotransferase activity", "id": "GO:0004134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004134", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H8", "url": "https://www.uniprot.org/uniprotkb/Q9W2H8" } ], "pmid": "" }, { "name": "amylo-alpha-1,6-glucosidase activity", "id": "GO:0004135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004135", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H8", "url": "https://www.uniprot.org/uniprotkb/Q9W2H8" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H8", "url": "https://www.uniprot.org/uniprotkb/Q9W2H8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H8", "url": "https://www.uniprot.org/uniprotkb/Q9W2H8" } ], "pmid": "" } ], "biological_process": [ { "name": "glycogen biosynthetic process", "id": "GO:0005978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005978", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H8", "url": "https://www.uniprot.org/uniprotkb/Q9W2H8" } ], "pmid": "" }, { "name": "glycogen catabolic process", "id": "GO:0005980", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005980", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H8", "url": "https://www.uniprot.org/uniprotkb/Q9W2H8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W2H8-1" }, { "uniprot_canonical_ac": "Q9VVE0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVE0", "url": "https://www.uniprot.org/uniprotkb/Q9VVE0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 145, "chemical_mass": 17055.0, "gene_names": "Pop5;CG14057;Dmel\\CG14057;Dmel_CG14057;Pop5", "protein_name": "Ribonuclease P/MRP protein subunit POP5", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VVE0", "url": "https://www.uniprot.org/uniprotkb/Q9VVE0" } ], "pmid": "" }, { "name": "ribonuclease P complex", "id": "GO:0030677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030677", "evidence": [ { "database": "UniProtKB", "id": "Q9VVE0", "url": "https://www.uniprot.org/uniprotkb/Q9VVE0" } ], "pmid": "" }, { "name": "nucleolar ribonuclease P complex", "id": "GO:0005655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005655", "evidence": [ { "database": "UniProtKB", "id": "Q9VVE0", "url": "https://www.uniprot.org/uniprotkb/Q9VVE0" } ], "pmid": "" }, { "name": "multimeric ribonuclease P complex", "id": "GO:0030681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030681", "evidence": [ { "database": "UniProtKB", "id": "Q9VVE0", "url": "https://www.uniprot.org/uniprotkb/Q9VVE0" } ], "pmid": "" }, { "name": "ribonuclease MRP complex", "id": "GO:0000172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000172", "evidence": [ { "database": "UniProtKB", "id": "Q9VVE0", "url": "https://www.uniprot.org/uniprotkb/Q9VVE0" } ], "pmid": "" } ], "biological_process": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "Q9VVE0", "url": "https://www.uniprot.org/uniprotkb/Q9VVE0" } ], "pmid": "" }, { "name": "tRNA 5'-leader removal", "id": "GO:0001682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001682", "evidence": [ { "database": "UniProtKB", "id": "Q9VVE0", "url": "https://www.uniprot.org/uniprotkb/Q9VVE0" } ], "pmid": "" }, { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "Q9VVE0", "url": "https://www.uniprot.org/uniprotkb/Q9VVE0" } ], "pmid": "" }, { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "Q9VVE0", "url": "https://www.uniprot.org/uniprotkb/Q9VVE0" } ], "pmid": "" } ], "molecular_function": [ { "name": "ribonuclease P RNA binding", "id": "GO:0033204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033204", "evidence": [ { "database": "UniProtKB", "id": "Q9VVE0", "url": "https://www.uniprot.org/uniprotkb/Q9VVE0" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9VVE0", "url": "https://www.uniprot.org/uniprotkb/Q9VVE0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VVE0-1" }, { "uniprot_canonical_ac": "X2JAR4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JAR4", "url": "https://www.uniprot.org/uniprotkb/X2JAR4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 254, "chemical_mass": 28273.0, "gene_names": "Dmel\\CG42780;CG42780;Dmel\\CG42780;Dmel_CG42780", "protein_name": "SCP domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "X2JAR4", "url": "https://www.uniprot.org/uniprotkb/X2JAR4" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "X2JAR4", "url": "https://www.uniprot.org/uniprotkb/X2JAR4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "X2JAR4-1" }, { "uniprot_canonical_ac": "Q9VT40-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 818, "chemical_mass": 91503.0, "gene_names": "nbs;6754;CG6754;Dmel\\CG6754;Dmel_CG6754;Dnbs1;NBS1;NBS;Nbs1;Nbs;dNbs1;l(3)67BDp;l(3)67BDr;l(3)e77A1;nbs1;nbs", "protein_name": "Nibrin", "disease": [ { "disease_id": "DOID:0014667", "name": "disease of metabolism", "description": "A disease that involves errors in metabolic processes of building or degradation of molecules.", "url": "https://disease-ontology.org/term/DOID:0014667", "evidence": [ { "id": "0014667", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0014667" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:12449", "name": "aplastic anemia", "description": "A normocytic anemia that is characterized by a deficiency of red blood cells, white blood cells and platelets produced by bone marrow.", "url": "https://disease-ontology.org/term/DOID:12449", "evidence": [ { "id": "12449", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12449" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1993", "name": "rectum cancer", "description": "A colorectal cancer that is located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:1993", "evidence": [ { "id": "1993", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1993" } ], "weight": 0.0 }, { "disease_id": "DOID:2394", "name": "ovarian cancer", "description": "A female reproductive organ cancer that is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:2394", "evidence": [ { "id": "2394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2394" } ], "weight": 0.0 }, { "disease_id": "DOID:5603", "name": "T-cell acute lymphoblastic leukemia", "description": "An acute lymphoblastic leukemia that is characterized by too many T-cell lymphoblasts found in the bone marrow and blood.", "url": "https://disease-ontology.org/term/DOID:5603", "evidence": [ { "id": "5603", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5603" } ], "weight": 0.0 }, { "disease_id": "DOID:7400", "name": "Nijmegen breakage syndrome", "description": "A syndrome characterized by chromosomal instability, microcephaly, growth retardation, immunodeficiency, cellular hypersensitivity to X-rays, and predisposition to cancer that has_material_basis_in homozygous or compound heterozygous mutation in NBN on chromosome 8q21.3.", "url": "https://disease-ontology.org/term/DOID:7400", "evidence": [ { "id": "7400", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7400" } ], "weight": 0.0 }, { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway in response to DNA damage", "id": "GO:0008630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008630", "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "pmid": "" }, { "name": "signal transduction in response to DNA damage", "id": "GO:0042770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042770", "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "pmid": "" }, { "name": "mitotic G2 DNA damage checkpoint signaling", "id": "GO:0007095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007095", "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "pmid": "" }, { "name": "double-strand break repair via synthesis-dependent strand annealing", "id": "GO:0045003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045003", "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "pmid": "" }, { "name": "DNA double-strand break processing", "id": "GO:0000729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000729", "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "pmid": "" } ], "cellular_component": [ { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "pmid": "" }, { "name": "Mre11 complex", "id": "GO:0030870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030870", "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "pmid": "" } ], "molecular_function": [ { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VT40-1" }, { "uniprot_canonical_ac": "Q9VZT7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1381, "chemical_mass": 157513.0, "gene_names": "Girdin;CG12734;Dmel\\CG12734;Dmel_CG12734;Girdin;girdin;mecA", "protein_name": "", "disease": [ { "disease_id": "DOID:0050986", "name": "spinocerebellar ataxia 40", "description": "An autosomal dominant cerebellar ataxia that is characterized by progressive gait abnormalities, dysarthria, tremor and hyporeflexia, has_material_basis_in mutation in the CCDC88C gene.", "url": "https://disease-ontology.org/term/DOID:0050986", "evidence": [ { "id": "0050986", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050986" } ], "weight": 0.0 }, { "disease_id": "DOID:10908", "name": "hydrocephalus", "description": "A cerebral degeneration characterized by an abnormal accumulation of cerebrospinal fluid in the ventricles of the brain, leading to progressive enlargement of the head.", "url": "https://disease-ontology.org/term/DOID:10908", "evidence": [ { "id": "10908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10908" } ], "weight": 0.0 } ], "biological_process": [ { "name": "epithelium migration", "id": "GO:0090132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090132", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" }, { "name": "dendrite development", "id": "GO:0016358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016358", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" }, { "name": "dendrite morphogenesis", "id": "GO:0048813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048813", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" }, { "name": "positive regulation of cell size", "id": "GO:0045793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045793", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" }, { "name": "cytoskeleton-dependent intracellular transport", "id": "GO:0030705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030705", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" }, { "name": "epithelial cell-cell adhesion", "id": "GO:0090136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090136", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" }, { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" }, { "name": "zonula adherens", "id": "GO:0005915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005915", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" }, { "name": "spot adherens junction", "id": "GO:0005914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005914", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" }, { "name": "sensory dendrite", "id": "GO:0071683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071683", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" }, { "name": "dynein light intermediate chain binding", "id": "GO:0051959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051959", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VZT7-1", "start_pos": "1280", "end_pos": "1280", "site_lbl": "Thr1280", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1280, "start_aa": "Thr", "end_pos": 1280, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1280", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VZT7-1", "start_pos": "1301", "end_pos": "1301", "site_lbl": "Thr1301", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1301, "start_aa": "Thr", "end_pos": 1301, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1301", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VZT7-1", "start_pos": "239", "end_pos": "239", "site_lbl": "Thr239", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 239, "start_aa": "Thr", "end_pos": 239, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr239", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VZT7-1" }, { "uniprot_canonical_ac": "Q9VUG6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VUG6", "url": "https://www.uniprot.org/uniprotkb/Q9VUG6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1333, "chemical_mass": 153969.0, "gene_names": "Dmel\\CG17177;CG17177;Dmel\\CG17177;Dmel_CG17177", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VUG6-1", "start_pos": "290", "end_pos": "290", "site_lbl": "Thr290", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 290, "start_aa": "Thr", "end_pos": 290, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr290", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VUG6", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VUG6" } ] } ] } ], "record_id": "Q9VUG6-1" }, { "uniprot_canonical_ac": "X2JAG8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JAG8", "url": "https://www.uniprot.org/uniprotkb/X2JAG8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 912, "chemical_mass": 104626.0, "gene_names": "Prp4k;BcDNA:GH04978;CG7028;Dmel\\CG7028;Dmel_CG7028;PRP4K;PRP4;Prp4k;prp4", "protein_name": "Serine/threonine-protein kinase PRP4 homolog", "disease": [], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "X2JAG8", "url": "https://www.uniprot.org/uniprotkb/X2JAG8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "X2JAG8", "url": "https://www.uniprot.org/uniprotkb/X2JAG8" } ], "pmid": "" } ], "cellular_component": [ { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "X2JAG8", "url": "https://www.uniprot.org/uniprotkb/X2JAG8" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "X2JAG8", "url": "https://www.uniprot.org/uniprotkb/X2JAG8" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "X2JAG8", "url": "https://www.uniprot.org/uniprotkb/X2JAG8" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "X2JAG8", "url": "https://www.uniprot.org/uniprotkb/X2JAG8" } ], "pmid": "" }, { "name": "mRNA cis splicing, via spliceosome", "id": "GO:0045292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045292", "evidence": [ { "database": "UniProtKB", "id": "X2JAG8", "url": "https://www.uniprot.org/uniprotkb/X2JAG8" } ], "pmid": "" }, { "name": "positive regulation of hippo signaling", "id": "GO:0035332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035332", "evidence": [ { "database": "UniProtKB", "id": "X2JAG8", "url": "https://www.uniprot.org/uniprotkb/X2JAG8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "X2JAG8-1", "start_pos": "263", "end_pos": "263", "site_lbl": "Thr263", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 263, "start_aa": "Thr", "end_pos": 263, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr263", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "X2JAG8-1", "start_pos": "350", "end_pos": "350", "site_lbl": "Thr350", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 350, "start_aa": "Thr", "end_pos": 350, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr350", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "X2JAG8-1", "start_pos": "498", "end_pos": "498", "site_lbl": "Thr498", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 498, "start_aa": "Thr", "end_pos": 498, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr498", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "X2JAG8-1" }, { "uniprot_canonical_ac": "X2JAX9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JAX9", "url": "https://www.uniprot.org/uniprotkb/X2JAX9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 589, "chemical_mass": 62924.0, "gene_names": "ect;CG11965;CG6611;DROECT;Difl;Dmel\\CG6611;Dmel_CG6611;Ifl;ect", "protein_name": "", "disease": [], "biological_process": [ { "name": "tube development", "id": "GO:0035295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035295", "evidence": [ { "database": "UniProtKB", "id": "X2JAX9", "url": "https://www.uniprot.org/uniprotkb/X2JAX9" } ], "pmid": "" }, { "name": "cuticle development", "id": "GO:0042335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042335", "evidence": [ { "database": "UniProtKB", "id": "X2JAX9", "url": "https://www.uniprot.org/uniprotkb/X2JAX9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "X2JAX9-1" }, { "uniprot_canonical_ac": "Q9VUR8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VUR8", "url": "https://www.uniprot.org/uniprotkb/Q9VUR8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 570, "chemical_mass": 64895.0, "gene_names": "Dmel\\CG13449;CG13449;Dmel\\CG13449;Dmel_CG13449", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VUR8-1", "start_pos": "131", "end_pos": "131", "site_lbl": "Thr131", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 131, "start_aa": "Thr", "end_pos": 131, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr131", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VUR8-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Thr133", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 133, "start_aa": "Thr", "end_pos": 133, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr133", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VUR8-1" }, { "uniprot_canonical_ac": "Q9VX92-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VX92", "url": "https://www.uniprot.org/uniprotkb/Q9VX92" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1552, "chemical_mass": 174299.0, "gene_names": "RhoGAP15B;CG4937;Dmel\\CG4937;Dmel_CG4937;RhoGAP15B;gap20", "protein_name": "", "disease": [], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "Q9VX92", "url": "https://www.uniprot.org/uniprotkb/Q9VX92" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,4,5-trisphosphate binding", "id": "GO:0005547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005547", "evidence": [ { "database": "UniProtKB", "id": "Q9VX92", "url": "https://www.uniprot.org/uniprotkb/Q9VX92" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q9VX92", "url": "https://www.uniprot.org/uniprotkb/Q9VX92" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "Q9VX92", "url": "https://www.uniprot.org/uniprotkb/Q9VX92" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VX92", "url": "https://www.uniprot.org/uniprotkb/Q9VX92" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q9VX92", "url": "https://www.uniprot.org/uniprotkb/Q9VX92" } ], "pmid": "" }, { "name": "generation of neurons", "id": "GO:0048699", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048699", "evidence": [ { "database": "UniProtKB", "id": "Q9VX92", "url": "https://www.uniprot.org/uniprotkb/Q9VX92" } ], "pmid": "" }, { "name": "imaginal disc-derived leg morphogenesis", "id": "GO:0007480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007480", "evidence": [ { "database": "UniProtKB", "id": "Q9VX92", "url": "https://www.uniprot.org/uniprotkb/Q9VX92" } ], "pmid": "" }, { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "Q9VX92", "url": "https://www.uniprot.org/uniprotkb/Q9VX92" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VX92-1", "start_pos": "1429", "end_pos": "1429", "site_lbl": "Thr1429", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1429, "start_aa": "Thr", "end_pos": 1429, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1429", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VX92-1" }, { "uniprot_canonical_ac": "Q9VU18-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VU18", "url": "https://www.uniprot.org/uniprotkb/Q9VU18" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 804, "chemical_mass": 90080.0, "gene_names": "CT30663;CG10948;CT30663;Dmel\\CG10948;Dmel_CG10948;cg10948", "protein_name": "RRM domain-containing protein", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q9VU18", "url": "https://www.uniprot.org/uniprotkb/Q9VU18" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "Q9VU18", "url": "https://www.uniprot.org/uniprotkb/Q9VU18" } ], "pmid": "" }, { "name": "protein disulfide isomerase activity", "id": "GO:0003756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003756", "evidence": [ { "database": "UniProtKB", "id": "Q9VU18", "url": "https://www.uniprot.org/uniprotkb/Q9VU18" } ], "pmid": "" }, { "name": "pre-mRNA binding", "id": "GO:0036002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036002", "evidence": [ { "database": "UniProtKB", "id": "Q9VU18", "url": "https://www.uniprot.org/uniprotkb/Q9VU18" } ], "pmid": "" } ], "cellular_component": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "Q9VU18", "url": "https://www.uniprot.org/uniprotkb/Q9VU18" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VU18", "url": "https://www.uniprot.org/uniprotkb/Q9VU18" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "Q9VU18", "url": "https://www.uniprot.org/uniprotkb/Q9VU18" } ], "pmid": "" } ], "biological_process": [ { "name": "ultradian rhythm", "id": "GO:0007624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007624", "evidence": [ { "database": "UniProtKB", "id": "Q9VU18", "url": "https://www.uniprot.org/uniprotkb/Q9VU18" } ], "pmid": "" }, { "name": "alternative mRNA splicing, via spliceosome", "id": "GO:0000380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000380", "evidence": [ { "database": "UniProtKB", "id": "Q9VU18", "url": "https://www.uniprot.org/uniprotkb/Q9VU18" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VU18-1", "start_pos": "199", "end_pos": "199", "site_lbl": "Thr199", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 199, "start_aa": "Thr", "end_pos": 199, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr199", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VU18-1" }, { "uniprot_canonical_ac": "Q9W523-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1537, "chemical_mass": 161977.0, "gene_names": "ph-d;CG3895;DROZFP;Dmel\\CG3895;Dmel_CG3895;EG:BACN25G24.3;PH-d;PHD;PH;Ph-d;PhD;Ph;ph-D;ph-d;ph[D];ph[d];phd;phm;ph", "protein_name": "", "disease": [ { "disease_id": "DOID:0070287", "name": "primary autosomal recessive microcephaly 11", "description": "A primary autosomal recessive microcephaly that has_material_basis_in homozygous or compound heterozygous mutation in the PHC1 gene on chromosome 12p13.", "url": "https://disease-ontology.org/term/DOID:0070287", "evidence": [ { "id": "0070287", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070287" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:6419", "name": "tetralogy of Fallot", "description": "", "url": "https://disease-ontology.org/term/DOID:6419", "evidence": [ { "id": "6419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6419" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "pmid": "" }, { "name": "PRC1 complex", "id": "GO:0035102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035102", "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "pmid": "" }, { "name": "polytene chromosome", "id": "GO:0005700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005700", "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "pmid": "" }, { "name": "syncytial blastoderm mitotic cell cycle", "id": "GO:0035186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035186", "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9W523-1", "start_pos": "1051", "end_pos": "1051", "site_lbl": "Thr1051", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1051, "start_aa": "Thr", "end_pos": 1051, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1051", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9W523-1", "start_pos": "1085", "end_pos": "1085", "site_lbl": "Thr1085", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1085, "start_aa": "Thr", "end_pos": 1085, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1085", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9W523-1", "start_pos": "1433", "end_pos": "1433", "site_lbl": "Thr1433", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1433, "start_aa": "Thr", "end_pos": 1433, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1433", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9W523-1", "start_pos": "89", "end_pos": "89", "site_lbl": "Thr89", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 89, "start_aa": "Thr", "end_pos": 89, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr89", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9W523-1" }, { "uniprot_canonical_ac": "A8JRE3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JRE3", "url": "https://www.uniprot.org/uniprotkb/A8JRE3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1703, "chemical_mass": 188738.0, "gene_names": "woc;CG5965;Dmel\\CG5965;Dmel_CG5965;WOC;Woc;woc", "protein_name": "", "disease": [ { "disease_id": "DOID:0050776", "name": "non-syndromic X-linked intellectual disability", "description": "A non-syndromic intellectual disability characterized by a X-linked inheritance pattern.", "url": "https://disease-ontology.org/term/DOID:0050776", "evidence": [ { "id": "0050776", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050776" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A8JRE3", "url": "https://www.uniprot.org/uniprotkb/A8JRE3" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A8JRE3", "url": "https://www.uniprot.org/uniprotkb/A8JRE3" } ], "pmid": "" }, { "name": "ecdysone biosynthetic process", "id": "GO:0006697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006697", "evidence": [ { "database": "UniProtKB", "id": "A8JRE3", "url": "https://www.uniprot.org/uniprotkb/A8JRE3" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A8JRE3", "url": "https://www.uniprot.org/uniprotkb/A8JRE3" } ], "pmid": "" } ], "cellular_component": [ { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A8JRE3", "url": "https://www.uniprot.org/uniprotkb/A8JRE3" } ], "pmid": "" }, { "name": "polytene chromosome interband", "id": "GO:0005705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005705", "evidence": [ { "database": "UniProtKB", "id": "A8JRE3", "url": "https://www.uniprot.org/uniprotkb/A8JRE3" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A8JRE3", "url": "https://www.uniprot.org/uniprotkb/A8JRE3" } ], "pmid": "" }, { "name": "euchromatin", "id": "GO:0000791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000791", "evidence": [ { "database": "UniProtKB", "id": "A8JRE3", "url": "https://www.uniprot.org/uniprotkb/A8JRE3" } ], "pmid": "" }, { "name": "heterochromatin", "id": "GO:0000792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000792", "evidence": [ { "database": "UniProtKB", "id": "A8JRE3", "url": "https://www.uniprot.org/uniprotkb/A8JRE3" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "A8JRE3", "url": "https://www.uniprot.org/uniprotkb/A8JRE3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A8JRE3-1", "start_pos": "1085", "end_pos": "1085", "site_lbl": "Thr1085", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1085, "start_aa": "Thr", "end_pos": 1085, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1085", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A8JRE3-1" }, { "uniprot_canonical_ac": "A0A0B4LIC4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LIC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LIC4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 880, "chemical_mass": 92528.0, "gene_names": "Dmel\\CG15803;lincRNA.804;CG15803;Dmel\\CG15803;Dmel_CG15803;lincRNA.804", "protein_name": "PDZ domain-containing protein", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LIC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LIC4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LIC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LIC4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4LIC4-1", "start_pos": "596", "end_pos": "596", "site_lbl": "Thr596", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 596, "start_aa": "Thr", "end_pos": 596, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr596", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A0A0B4LIC4-1" }, { "uniprot_canonical_ac": "X2J9P4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2J9P4", "url": "https://www.uniprot.org/uniprotkb/X2J9P4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 940, "chemical_mass": 105730.0, "gene_names": "Dpp10;CG11319;DPP10;Dmel\\CG11319;Dmel_CG11319;Dpp10", "protein_name": "Venom dipeptidyl peptidase 4", "disease": [ { "disease_id": "DOID:0070063", "name": "autosomal dominant intellectual developmental disorder 33", "description": "An autosomal dominant intellectual developmental disorder that has_material_basis_in an autosomal dominant mutation of the DPP6 gene on chromosome 7q36.2.", "url": "https://disease-ontology.org/term/DOID:0070063", "evidence": [ { "id": "0070063", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070063" } ], "weight": 0.0 }, { "disease_id": "DOID:12377", "name": "spinal muscular atrophy", "description": "A motor neuron disease that is a degenerative neuromuscular disease characterized by lower motor neuron degeneration associated with progressive muscle weakness and atrophy.", "url": "https://disease-ontology.org/term/DOID:12377", "evidence": [ { "id": "12377", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12377" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:332", "name": "amyotrophic lateral sclerosis", "description": "A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.", "url": "https://disease-ontology.org/term/DOID:332", "evidence": [ { "id": "332", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:332" } ], "weight": 0.0 } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "X2J9P4", "url": "https://www.uniprot.org/uniprotkb/X2J9P4" } ], "pmid": "" }, { "name": "regulation of potassium ion transmembrane transport", "id": "GO:1901379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901379", "evidence": [ { "database": "UniProtKB", "id": "X2J9P4", "url": "https://www.uniprot.org/uniprotkb/X2J9P4" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "X2J9P4", "url": "https://www.uniprot.org/uniprotkb/X2J9P4" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "X2J9P4", "url": "https://www.uniprot.org/uniprotkb/X2J9P4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "X2J9P4", "url": "https://www.uniprot.org/uniprotkb/X2J9P4" } ], "pmid": "" }, { "name": "Kv4.3-DPP10 channel complex", "id": "GO:0071202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071202", "evidence": [ { "database": "UniProtKB", "id": "X2J9P4", "url": "https://www.uniprot.org/uniprotkb/X2J9P4" } ], "pmid": "" } ], "molecular_function": [ { "name": "aminopeptidase activity", "id": "GO:0004177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004177", "evidence": [ { "database": "UniProtKB", "id": "X2J9P4", "url": "https://www.uniprot.org/uniprotkb/X2J9P4" } ], "pmid": "" }, { "name": "serine-type peptidase activity", "id": "GO:0008236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008236", "evidence": [ { "database": "UniProtKB", "id": "X2J9P4", "url": "https://www.uniprot.org/uniprotkb/X2J9P4" } ], "pmid": "" }, { "name": "dipeptidyl-peptidase activity", "id": "GO:0008239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008239", "evidence": [ { "database": "UniProtKB", "id": "X2J9P4", "url": "https://www.uniprot.org/uniprotkb/X2J9P4" } ], "pmid": "" }, { "name": "potassium channel regulator activity", "id": "GO:0015459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015459", "evidence": [ { "database": "UniProtKB", "id": "X2J9P4", "url": "https://www.uniprot.org/uniprotkb/X2J9P4" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "X2J9P4", "url": "https://www.uniprot.org/uniprotkb/X2J9P4" } ], "pmid": "" }, { "name": "serine hydrolase activity", "id": "GO:0017171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017171", "evidence": [ { "database": "UniProtKB", "id": "X2J9P4", "url": "https://www.uniprot.org/uniprotkb/X2J9P4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "X2J9P4-1", "start_pos": "621", "end_pos": "621", "site_lbl": "Thr621", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 621, "start_aa": "Thr", "end_pos": 621, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr621", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "X2J9P4-1" }, { "uniprot_canonical_ac": "Q9VPI7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPI7", "url": "https://www.uniprot.org/uniprotkb/Q9VPI7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 401, "chemical_mass": 46753.0, "gene_names": "Dmel\\CG11374;CG11374;Dmel\\CG11374;Dmel_CG11374", "protein_name": "Galectin", "disease": [], "molecular_function": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI7", "url": "https://www.uniprot.org/uniprotkb/Q9VPI7" } ], "pmid": "" }, { "name": "galactoside binding", "id": "GO:0016936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016936", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI7", "url": "https://www.uniprot.org/uniprotkb/Q9VPI7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VPI7-1", "start_pos": "271", "end_pos": "271", "site_lbl": "Thr271", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 271, "start_aa": "Thr", "end_pos": 271, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr271", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VPI7-1" }, { "uniprot_canonical_ac": "Q9VPJ1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPJ1", "url": "https://www.uniprot.org/uniprotkb/Q9VPJ1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 649, "chemical_mass": 71283.0, "gene_names": "Nhe1;CG12178;DmNHE1;Dmel\\CG12178;Dmel_CG12178;NHE1;Nhe1;nhe1", "protein_name": "Sodium/hydrogen exchanger", "disease": [], "molecular_function": [ { "name": "sodium:proton antiporter activity", "id": "GO:0015385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015385", "evidence": [ { "database": "UniProtKB", "id": "Q9VPJ1", "url": "https://www.uniprot.org/uniprotkb/Q9VPJ1" } ], "pmid": "" }, { "name": "potassium:proton antiporter activity", "id": "GO:0015386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015386", "evidence": [ { "database": "UniProtKB", "id": "Q9VPJ1", "url": "https://www.uniprot.org/uniprotkb/Q9VPJ1" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q9VPJ1", "url": "https://www.uniprot.org/uniprotkb/Q9VPJ1" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of intracellular pH", "id": "GO:0051453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051453", "evidence": [ { "database": "UniProtKB", "id": "Q9VPJ1", "url": "https://www.uniprot.org/uniprotkb/Q9VPJ1" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "Q9VPJ1", "url": "https://www.uniprot.org/uniprotkb/Q9VPJ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VPJ1-1" }, { "uniprot_canonical_ac": "Q9VPL8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPL8", "url": "https://www.uniprot.org/uniprotkb/Q9VPL8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 443, "chemical_mass": 51460.0, "gene_names": "Dmel\\CG13693;CG13693;Dmel\\CG13693;Dmel_CG13693", "protein_name": "Cilia- and flagella-associated protein 263", "disease": [], "biological_process": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "Q9VPL8", "url": "https://www.uniprot.org/uniprotkb/Q9VPL8" } ], "pmid": "" } ], "cellular_component": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "Q9VPL8", "url": "https://www.uniprot.org/uniprotkb/Q9VPL8" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "Q9VPL8", "url": "https://www.uniprot.org/uniprotkb/Q9VPL8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VPL8-1" }, { "uniprot_canonical_ac": "Q9VPN8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPN8", "url": "https://www.uniprot.org/uniprotkb/Q9VPN8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 277, "chemical_mass": 30136.0, "gene_names": "SP103;CG11911;Dmel\\CG11911;Dmel_CG11911;SP103", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN8", "url": "https://www.uniprot.org/uniprotkb/Q9VPN8" } ], "pmid": "" }, { "name": "serine hydrolase activity", "id": "GO:0017171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017171", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN8", "url": "https://www.uniprot.org/uniprotkb/Q9VPN8" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN8", "url": "https://www.uniprot.org/uniprotkb/Q9VPN8" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN8", "url": "https://www.uniprot.org/uniprotkb/Q9VPN8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VPN8-1" }, { "uniprot_canonical_ac": "Q9VPP9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPP9", "url": "https://www.uniprot.org/uniprotkb/Q9VPP9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 549, "chemical_mass": 60746.0, "gene_names": "BBS8;BBS2;BBS8;CG13691;Dmel\\CG13691;Dmel_CG13691", "protein_name": "", "disease": [ { "disease_id": "DOID:0060340", "name": "ciliopathy", "description": "A syndrome associated with mutations encoding defective proteins, which result in either abnormal function formation or function of cilia.", "url": "https://disease-ontology.org/term/DOID:0060340", "evidence": [ { "id": "0060340", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060340" } ], "weight": 0.0 }, { "disease_id": "DOID:0110130", "name": "Bardet-Biedl syndrome 8", "description": "A Bardet-Biedl syndrome that has_material_basis_in homozygous mutation in the TTC8 gene on chromosome 14q31.", "url": "https://disease-ontology.org/term/DOID:0110130", "evidence": [ { "id": "0110130", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110130" } ], "weight": 0.0 }, { "disease_id": "DOID:0110398", "name": "retinitis pigmentosa 51", "description": "A retinitis pigmentosa that has_material_basis_in mutation in the TTC8 gene on chromosome 14q31.", "url": "https://disease-ontology.org/term/DOID:0110398", "evidence": [ { "id": "0110398", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110398" } ], "weight": 0.0 }, { "disease_id": "DOID:1935", "name": "Bardet-Biedl syndrome", "description": "A syndrome that results from mutations in multiple BBS genes affecting cellular cilia structure or function (ciliopathy) resulting in variable presentation and characterized principally by obesity, retinitis pigmentosa,vision loss, polydactyly, mental retardation, hypogonadism, and renal failure in some cases.", "url": "https://disease-ontology.org/term/DOID:1935", "evidence": [ { "id": "1935", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1935" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "Q9VPP9", "url": "https://www.uniprot.org/uniprotkb/Q9VPP9" } ], "pmid": "" }, { "name": "non-motile cilium", "id": "GO:0097730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097730", "evidence": [ { "database": "UniProtKB", "id": "Q9VPP9", "url": "https://www.uniprot.org/uniprotkb/Q9VPP9" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "Q9VPP9", "url": "https://www.uniprot.org/uniprotkb/Q9VPP9" } ], "pmid": "" }, { "name": "BBSome", "id": "GO:0034464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034464", "evidence": [ { "database": "UniProtKB", "id": "Q9VPP9", "url": "https://www.uniprot.org/uniprotkb/Q9VPP9" } ], "pmid": "" } ], "biological_process": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "Q9VPP9", "url": "https://www.uniprot.org/uniprotkb/Q9VPP9" } ], "pmid": "" }, { "name": "non-motile cilium assembly", "id": "GO:1905515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905515", "evidence": [ { "database": "UniProtKB", "id": "Q9VPP9", "url": "https://www.uniprot.org/uniprotkb/Q9VPP9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VPP9-1" }, { "uniprot_canonical_ac": "Q9VPS9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPS9", "url": "https://www.uniprot.org/uniprotkb/Q9VPS9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 99, "chemical_mass": 9605.0, "gene_names": "Dmel\\CG13946;CG13946;Dmel\\CG13946;Dmel_CG13946", "protein_name": "Tenecin-3-like", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VPS9-1" }, { "uniprot_canonical_ac": "Q9VPW6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPW6", "url": "https://www.uniprot.org/uniprotkb/Q9VPW6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 264, "chemical_mass": 29928.0, "gene_names": "Dmel\\CG14340;CG14340;Dmel\\CG14340;Dmel_CG14340", "protein_name": "", "disease": [], "biological_process": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW6", "url": "https://www.uniprot.org/uniprotkb/Q9VPW6" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW6", "url": "https://www.uniprot.org/uniprotkb/Q9VPW6" } ], "pmid": "" }, { "name": "negative regulation of signal transduction", "id": "GO:0009968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009968", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW6", "url": "https://www.uniprot.org/uniprotkb/Q9VPW6" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW6", "url": "https://www.uniprot.org/uniprotkb/Q9VPW6" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW6", "url": "https://www.uniprot.org/uniprotkb/Q9VPW6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VPW6-1" }, { "uniprot_canonical_ac": "Q9VPW9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPW9", "url": "https://www.uniprot.org/uniprotkb/Q9VPW9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 689, "chemical_mass": 77472.0, "gene_names": "TBC1D23;CG4552;Dmel\\CG4552;Dmel_CG4552;TBC1D23;tbc1", "protein_name": "TBC1 domain family member 23", "disease": [ { "disease_id": "DOID:0060264", "name": "pontocerebellar hypoplasia", "description": "A neurodegenerative disease that is characterized by underdevelopment of the pons and cerebellum.", "url": "https://disease-ontology.org/term/DOID:0060264", "evidence": [ { "id": "0060264", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060264" } ], "weight": 0.0 }, { "disease_id": "DOID:0112324", "name": "pontocerebellar hypoplasia type 11", "description": "A pontocerebellar hypoplasia characterized by severely delayed psychomotor development with intellectual disability and poor speech, microcephaly, dysmorphic features, and pontocerebellar hypoplasia on brain imaging that has_material_basis_in homozygous or compound heterozygous mutation in the TBC1D23 gene on chromosome 3q12.1-q12.2.", "url": "https://disease-ontology.org/term/DOID:0112324", "evidence": [ { "id": "0112324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112324" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW9", "url": "https://www.uniprot.org/uniprotkb/Q9VPW9" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW9", "url": "https://www.uniprot.org/uniprotkb/Q9VPW9" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW9", "url": "https://www.uniprot.org/uniprotkb/Q9VPW9" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW9", "url": "https://www.uniprot.org/uniprotkb/Q9VPW9" } ], "pmid": "" } ], "biological_process": [ { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW9", "url": "https://www.uniprot.org/uniprotkb/Q9VPW9" } ], "pmid": "" }, { "name": "vesicle tethering to Golgi", "id": "GO:0099041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099041", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW9", "url": "https://www.uniprot.org/uniprotkb/Q9VPW9" } ], "pmid": "" }, { "name": "positive regulation of intracellular transport", "id": "GO:0032388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032388", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW9", "url": "https://www.uniprot.org/uniprotkb/Q9VPW9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VPW9-1" }, { "uniprot_canonical_ac": "Q9VQ50-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQ50", "url": "https://www.uniprot.org/uniprotkb/Q9VQ50" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 673, "chemical_mass": 78460.0, "gene_names": "gi22945479;CG15622;CG31933;Dmel\\CG31933;Dmel_CG31933;gi21064045;gi22945479", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VQ50-1" }, { "uniprot_canonical_ac": "Q9VQ88-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQ88", "url": "https://www.uniprot.org/uniprotkb/Q9VQ88" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 77, "chemical_mass": 8563.0, "gene_names": "Dmel\\CG15386;CG15386;Dmel\\CG15386;Dmel_CG15386", "protein_name": "", "disease": [], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ88", "url": "https://www.uniprot.org/uniprotkb/Q9VQ88" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial respiratory chain complex III assembly", "id": "GO:0034551", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034551", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ88", "url": "https://www.uniprot.org/uniprotkb/Q9VQ88" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VQ88-1" }, { "uniprot_canonical_ac": "Q9VQA4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQA4", "url": "https://www.uniprot.org/uniprotkb/Q9VQA4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 242, "chemical_mass": 26991.0, "gene_names": "Dmel\\CG4271;CG4271;Dmel\\CG4271;Dmel_CG4271;SPH164", "protein_name": "trypsin", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VQA4", "url": "https://www.uniprot.org/uniprotkb/Q9VQA4" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VQA4", "url": "https://www.uniprot.org/uniprotkb/Q9VQA4" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q9VQA4", "url": "https://www.uniprot.org/uniprotkb/Q9VQA4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VQA4-1" }, { "uniprot_canonical_ac": "Q9VQD0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQD0", "url": "https://www.uniprot.org/uniprotkb/Q9VQD0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 235, "chemical_mass": 27908.0, "gene_names": "Dmel\\CG3528;CG3528;Dmel\\CG3528;Dmel_CG3528", "protein_name": "Cilia- and flagella-associated protein 299", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD0", "url": "https://www.uniprot.org/uniprotkb/Q9VQD0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD0", "url": "https://www.uniprot.org/uniprotkb/Q9VQD0" } ], "pmid": "" } ], "biological_process": [ { "name": "motile cilium assembly", "id": "GO:0044458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044458", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD0", "url": "https://www.uniprot.org/uniprotkb/Q9VQD0" } ], "pmid": "" }, { "name": "non-motile cilium assembly", "id": "GO:1905515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905515", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD0", "url": "https://www.uniprot.org/uniprotkb/Q9VQD0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VQD0-1" }, { "uniprot_canonical_ac": "Q9VQH8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQH8", "url": "https://www.uniprot.org/uniprotkb/Q9VQH8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 343, "chemical_mass": 37881.0, "gene_names": "c-SPH125;CG18557;Dmel\\CG18557;Dmel_CG18557;c-SPH125;cSPH125", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VQH8", "url": "https://www.uniprot.org/uniprotkb/Q9VQH8" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VQH8", "url": "https://www.uniprot.org/uniprotkb/Q9VQH8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VQH8-1" }, { "uniprot_canonical_ac": "Q9VQH9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQH9", "url": "https://www.uniprot.org/uniprotkb/Q9VQH9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 347, "chemical_mass": 37884.0, "gene_names": "c-SPH94;CG3117;Dmel\\CG3117;Dmel_CG3117;SPH94;c-SPH94;cSPH94", "protein_name": "Phenoloxidase-activating factor 2", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VQH9", "url": "https://www.uniprot.org/uniprotkb/Q9VQH9" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VQH9", "url": "https://www.uniprot.org/uniprotkb/Q9VQH9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VQH9-1" }, { "uniprot_canonical_ac": "Q9VQL9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQL9", "url": "https://www.uniprot.org/uniprotkb/Q9VQL9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 336, "chemical_mass": 38322.0, "gene_names": "PpD6;CG8822;D6;Dmel\\CG8822;Dmel_CG8822;PP1;PPD6;PpD6", "protein_name": "Serine/threonine-protein phosphatase", "disease": [], "biological_process": [ { "name": "male meiosis chromosome segregation", "id": "GO:0007060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007060", "evidence": [ { "database": "UniProtKB", "id": "Q9VQL9", "url": "https://www.uniprot.org/uniprotkb/Q9VQL9" } ], "pmid": "" }, { "name": "egg-laying behavior", "id": "GO:0018991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018991", "evidence": [ { "database": "UniProtKB", "id": "Q9VQL9", "url": "https://www.uniprot.org/uniprotkb/Q9VQL9" } ], "pmid": "" }, { "name": "regulation of pseudopodium assembly", "id": "GO:0031272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031272", "evidence": [ { "database": "UniProtKB", "id": "Q9VQL9", "url": "https://www.uniprot.org/uniprotkb/Q9VQL9" } ], "pmid": "" }, { "name": "amoeboid sperm motility", "id": "GO:0097723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097723", "evidence": [ { "database": "UniProtKB", "id": "Q9VQL9", "url": "https://www.uniprot.org/uniprotkb/Q9VQL9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VQL9", "url": "https://www.uniprot.org/uniprotkb/Q9VQL9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VQL9", "url": "https://www.uniprot.org/uniprotkb/Q9VQL9" } ], "pmid": "" }, { "name": "pseudopodium", "id": "GO:0031143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031143", "evidence": [ { "database": "UniProtKB", "id": "Q9VQL9", "url": "https://www.uniprot.org/uniprotkb/Q9VQL9" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VQL9", "url": "https://www.uniprot.org/uniprotkb/Q9VQL9" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "Q9VQL9", "url": "https://www.uniprot.org/uniprotkb/Q9VQL9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VQL9-1" }, { "uniprot_canonical_ac": "Q9VQP2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQP2", "url": "https://www.uniprot.org/uniprotkb/Q9VQP2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 466, "chemical_mass": 51764.0, "gene_names": "Dmel\\CG15408;CG15408;Dmel\\CG15408;Dmel_CG15408", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "disease": [], "molecular_function": [ { "name": "sugar transmembrane transporter activity", "id": "GO:0051119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051119", "evidence": [ { "database": "UniProtKB", "id": "Q9VQP2", "url": "https://www.uniprot.org/uniprotkb/Q9VQP2" } ], "pmid": "" }, { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "Q9VQP2", "url": "https://www.uniprot.org/uniprotkb/Q9VQP2" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VQP2", "url": "https://www.uniprot.org/uniprotkb/Q9VQP2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VQP2", "url": "https://www.uniprot.org/uniprotkb/Q9VQP2" } ], "pmid": "" } ], "biological_process": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "Q9VQP2", "url": "https://www.uniprot.org/uniprotkb/Q9VQP2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VQP2-1" }, { "uniprot_canonical_ac": "R9PY49-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "R9PY49", "url": "https://www.uniprot.org/uniprotkb/R9PY49" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 723, "chemical_mass": 83814.0, "gene_names": "Dmel\\CG8851;CG8851;Dmel\\CG8851;Dmel_CG8851", "protein_name": "", "disease": [], "cellular_component": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "R9PY49", "url": "https://www.uniprot.org/uniprotkb/R9PY49" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of cilium assembly", "id": "GO:1902017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902017", "evidence": [ { "database": "UniProtKB", "id": "R9PY49", "url": "https://www.uniprot.org/uniprotkb/R9PY49" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "R9PY49-1" }, { "uniprot_canonical_ac": "Q9VR48-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VR48", "url": "https://www.uniprot.org/uniprotkb/Q9VR48" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 846, "chemical_mass": 94691.0, "gene_names": "hoe2;CG15624;Dmel\\CG15624;Dmel_CG15624;hoe2", "protein_name": "", "disease": [ { "disease_id": "DOID:0050632", "name": "oculocutaneous albinism", "description": "A syndrome characterized by abnormal pigmentation of the skin, hair and eyes.", "url": "https://disease-ontology.org/term/DOID:0050632", "evidence": [ { "id": "0050632", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050632" } ], "weight": 0.0 }, { "disease_id": "DOID:0070096", "name": "oculocutaneous albinism type II", "description": "An oculocutaneous albinism that has_material_basis_in an autosomal recessive mutation of the OCA2 gene on chromosome 15q12-q13.", "url": "https://disease-ontology.org/term/DOID:0070096", "evidence": [ { "id": "0070096", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070096" } ], "weight": 0.0 }, { "disease_id": "DOID:10123", "name": "pigmentation disease", "description": "A skin disease that is characterized by discoloration of the skin.", "url": "https://disease-ontology.org/term/DOID:10123", "evidence": [ { "id": "10123", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10123" } ], "weight": 0.0 }, { "disease_id": "DOID:1749", "name": "squamous cell carcinoma", "description": "A carcinoma that derives_from squamous epithelial cells.", "url": "https://disease-ontology.org/term/DOID:1749", "evidence": [ { "id": "1749", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1749" } ], "weight": 0.0 }, { "disease_id": "DOID:2513", "name": "basal cell carcinoma", "description": "A skin carcinoma affecting basal cells.", "url": "https://disease-ontology.org/term/DOID:2513", "evidence": [ { "id": "2513", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2513" } ], "weight": 0.0 }, { "disease_id": "DOID:8866", "name": "actinic keratosis", "description": "", "url": "https://disease-ontology.org/term/DOID:8866", "evidence": [ { "id": "8866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8866" } ], "weight": 0.0 }, { "disease_id": "DOID:8923", "name": "skin melanoma", "description": "A skin cancer that has_material_basis_in melanocytes.", "url": "https://disease-ontology.org/term/DOID:8923", "evidence": [ { "id": "8923", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8923" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VR48", "url": "https://www.uniprot.org/uniprotkb/Q9VR48" } ], "pmid": "" } ], "molecular_function": [ { "name": "monoatomic ion transmembrane transporter activity", "id": "GO:0015075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015075", "evidence": [ { "database": "UniProtKB", "id": "Q9VR48", "url": "https://www.uniprot.org/uniprotkb/Q9VR48" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VR48-1" }, { "uniprot_canonical_ac": "Q9VR92-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VR92", "url": "https://www.uniprot.org/uniprotkb/Q9VR92" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 302, "chemical_mass": 32593.0, "gene_names": "Dmel\\CG15459;CG15459;Dmel\\CG15459;Dmel_CG15459", "protein_name": "", "disease": [ { "disease_id": "DOID:0111749", "name": "mitochondrial complex V (ATP synthase) deficiency nuclear type 6", "description": "A mitochondrial complex V (ATP synthase) deficiency characterized by episodic regression of gross motor skills beginning in early childhood that has_material_basis_in homozygous or compound heterozygous mutation in the ATP5MD gene on chromosome 10q24.33.", "url": "https://disease-ontology.org/term/DOID:0111749", "evidence": [ { "id": "0111749", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111749" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q9VR92", "url": "https://www.uniprot.org/uniprotkb/Q9VR92" } ], "pmid": "" }, { "name": "proton-transporting ATP synthase complex", "id": "GO:0045259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045259", "evidence": [ { "database": "UniProtKB", "id": "Q9VR92", "url": "https://www.uniprot.org/uniprotkb/Q9VR92" } ], "pmid": "" } ], "biological_process": [ { "name": "proton motive force-driven ATP synthesis", "id": "GO:0015986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015986", "evidence": [ { "database": "UniProtKB", "id": "Q9VR92", "url": "https://www.uniprot.org/uniprotkb/Q9VR92" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VR92-1", "start_pos": "117", "end_pos": "117", "site_lbl": "Thr117", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 117, "start_aa": "Thr", "end_pos": 117, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr117", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VR92-1" }, { "uniprot_canonical_ac": "Q9VRG5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VRG5", "url": "https://www.uniprot.org/uniprotkb/Q9VRG5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1655, "chemical_mass": 190269.0, "gene_names": "Dmel\\CG1801;CG1801;DmCG1801;Dmel\\CG1801;Dmel_CG1801", "protein_name": "ABC transporter domain-containing protein", "disease": [], "molecular_function": [ { "name": "lipid transporter activity", "id": "GO:0005319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005319", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG5", "url": "https://www.uniprot.org/uniprotkb/Q9VRG5" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG5", "url": "https://www.uniprot.org/uniprotkb/Q9VRG5" } ], "pmid": "" }, { "name": "ATPase-coupled transmembrane transporter activity", "id": "GO:0042626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042626", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG5", "url": "https://www.uniprot.org/uniprotkb/Q9VRG5" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG5", "url": "https://www.uniprot.org/uniprotkb/Q9VRG5" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG5", "url": "https://www.uniprot.org/uniprotkb/Q9VRG5" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG5", "url": "https://www.uniprot.org/uniprotkb/Q9VRG5" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG5", "url": "https://www.uniprot.org/uniprotkb/Q9VRG5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VRG5-1" }, { "uniprot_canonical_ac": "Q9VRI3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VRI3", "url": "https://www.uniprot.org/uniprotkb/Q9VRI3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 183, "chemical_mass": 17014.0, "gene_names": "Dmel\\CG10918;CG10918;Dmel\\CG10918;Dmel_CG10918", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VRI3", "url": "https://www.uniprot.org/uniprotkb/Q9VRI3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VRI3-1" }, { "uniprot_canonical_ac": "Q9VRM0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VRM0", "url": "https://www.uniprot.org/uniprotkb/Q9VRM0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 542, "chemical_mass": 60814.0, "gene_names": "Lkr;CG10626;DLKR;Dmel\\CG10626;Dmel_CG10626;LK-R;LKR;LkR;Lkr;anon-WO0131005.17;anon-WO0170980.118;anon-WO0170980.119;dLKR;lkr", "protein_name": "", "disease": [], "biological_process": [ { "name": "negative regulation of feeding behavior", "id": "GO:2000252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000252", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM0", "url": "https://www.uniprot.org/uniprotkb/Q9VRM0" } ], "pmid": "" }, { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM0", "url": "https://www.uniprot.org/uniprotkb/Q9VRM0" } ], "pmid": "" }, { "name": "positive regulation of cytosolic calcium ion concentration", "id": "GO:0007204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007204", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM0", "url": "https://www.uniprot.org/uniprotkb/Q9VRM0" } ], "pmid": "" } ], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM0", "url": "https://www.uniprot.org/uniprotkb/Q9VRM0" } ], "pmid": "" }, { "name": "neuropeptide receptor activity", "id": "GO:0008188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008188", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM0", "url": "https://www.uniprot.org/uniprotkb/Q9VRM0" } ], "pmid": "" }, { "name": "neuropeptide Y receptor activity", "id": "GO:0004983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004983", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM0", "url": "https://www.uniprot.org/uniprotkb/Q9VRM0" } ], "pmid": "" }, { "name": "leucokinin receptor activity", "id": "GO:0042071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042071", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM0", "url": "https://www.uniprot.org/uniprotkb/Q9VRM0" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM0", "url": "https://www.uniprot.org/uniprotkb/Q9VRM0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM0", "url": "https://www.uniprot.org/uniprotkb/Q9VRM0" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM0", "url": "https://www.uniprot.org/uniprotkb/Q9VRM0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VRM0-1", "start_pos": "431", "end_pos": "431", "site_lbl": "Thr431", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 431, "start_aa": "Thr", "end_pos": 431, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr431", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VRM0-1" }, { "uniprot_canonical_ac": "Q9VRP4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VRP4", "url": "https://www.uniprot.org/uniprotkb/Q9VRP4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 518, "chemical_mass": 57641.0, "gene_names": "Ppat-Dpck;CG10575;DPCK/PPAT;Dmel\\CG10575;Dmel_CG10575;PPAT-DPCK;PPAT;Ppat-Dpck;dCOASY;dPPAT-DPCK", "protein_name": "Bifunctional coenzyme A synthase", "disease": [ { "disease_id": "DOID:0110740", "name": "neurodegeneration with brain iron accumulation 6", "description": "A neurodegeneration with brain iron accumulation that has_material_basis_in autosomal recessive inheritance of mutation in the COASY gene on chromosome 17q21.2.", "url": "https://disease-ontology.org/term/DOID:0110740", "evidence": [ { "id": "0110740", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110740" } ], "weight": 0.0 }, { "disease_id": "DOID:0112327", "name": "pontocerebellar hypoplasia type 12", "description": "A pontocerebellar hypoplasia that has_material_basis_in homozygous or compound heterozygous mutation in the COASY gene on chromosome 17q21.2.", "url": "https://disease-ontology.org/term/DOID:0112327", "evidence": [ { "id": "0112327", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112327" } ], "weight": 0.0 }, { "disease_id": "DOID:12801", "name": "mucopolysaccharidosis III", "description": "A mucopolysaccharidosis characterized by a deficiency of the lysosomal enzyme resulting in incomplete breakdown of the heparan sulfate sugar chain.", "url": "https://disease-ontology.org/term/DOID:12801", "evidence": [ { "id": "12801", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12801" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "dephospho-CoA kinase activity", "id": "GO:0004140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004140", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP4", "url": "https://www.uniprot.org/uniprotkb/Q9VRP4" } ], "pmid": "" }, { "name": "pantetheine-phosphate adenylyltransferase activity", "id": "GO:0004595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004595", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP4", "url": "https://www.uniprot.org/uniprotkb/Q9VRP4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP4", "url": "https://www.uniprot.org/uniprotkb/Q9VRP4" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP4", "url": "https://www.uniprot.org/uniprotkb/Q9VRP4" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP4", "url": "https://www.uniprot.org/uniprotkb/Q9VRP4" } ], "pmid": "" } ], "biological_process": [ { "name": "triglyceride homeostasis", "id": "GO:0070328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070328", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP4", "url": "https://www.uniprot.org/uniprotkb/Q9VRP4" } ], "pmid": "" }, { "name": "coenzyme A biosynthetic process", "id": "GO:0015937", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015937", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP4", "url": "https://www.uniprot.org/uniprotkb/Q9VRP4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VRP4-1", "start_pos": "229", "end_pos": "229", "site_lbl": "Thr229", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 229, "start_aa": "Thr", "end_pos": 229, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr229", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VRP4-1" }, { "uniprot_canonical_ac": "Q9VRT4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VRT4", "url": "https://www.uniprot.org/uniprotkb/Q9VRT4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 662, "chemical_mass": 73186.0, "gene_names": "CG6596;CG42269;CG6596;CG6600;Dmel\\CG42269;Dmel_CG42269", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "disease": [ { "disease_id": "DOID:13619", "name": "extrahepatic cholestasis", "description": "A cholestasis resulting from causes located_in bile ducts outside the liver.", "url": "https://disease-ontology.org/term/DOID:13619", "evidence": [ { "id": "13619", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13619" } ], "weight": 0.0 }, { "disease_id": "DOID:1852", "name": "intrahepatic cholestasis", "description": "A cholestasis characterized by impairment of the bile flow caused by obstruction located_in liver.", "url": "https://disease-ontology.org/term/DOID:1852", "evidence": [ { "id": "1852", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1852" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:3021", "name": "acute kidney failure", "description": "", "url": "https://disease-ontology.org/term/DOID:3021", "evidence": [ { "id": "3021", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3021" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VRT4", "url": "https://www.uniprot.org/uniprotkb/Q9VRT4" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "Q9VRT4", "url": "https://www.uniprot.org/uniprotkb/Q9VRT4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VRT4-1" }, { "uniprot_canonical_ac": "Q9VS65-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VS65", "url": "https://www.uniprot.org/uniprotkb/Q9VS65" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 344, "chemical_mass": 39884.0, "gene_names": "CG18415;CG18415;CG32379;Dmel\\CG32379;Dmel_CG32379", "protein_name": "Peptidase M14 domain-containing protein", "disease": [ { "disease_id": "DOID:0060752", "name": "familial temporal lobe epilepsy 5", "description": "A temporal lobe epilepsy that has_material_basis_in heterozygous mutation in the CPA6 gene on chromosome 8q13.", "url": "https://disease-ontology.org/term/DOID:0060752", "evidence": [ { "id": "0060752", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060752" } ], "weight": 0.0 }, { "disease_id": "DOID:0111308", "name": "familial febrile seizures 11", "description": "A familial febrile seizures that has_material_basis_in homozygous mutation in the CPA6 gene on chromosome 8p13.2.", "url": "https://disease-ontology.org/term/DOID:0111308", "evidence": [ { "id": "0111308", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111308" } ], "weight": 0.0 }, { "disease_id": "DOID:1184", "name": "nephrotic syndrome", "description": "A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.", "url": "https://disease-ontology.org/term/DOID:1184", "evidence": [ { "id": "1184", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1184" } ], "weight": 0.0 }, { "disease_id": "DOID:13241", "name": "Behcet's disease", "description": "An autoimmune disease that is characterized by mucocutaneous manifestations, including recurrent oral and genital ulcerations, ocular manifestations, especially chronic relapsing uveitis, and systemic vasculitis involving arteries and veins of all sizes.", "url": "https://disease-ontology.org/term/DOID:13241", "evidence": [ { "id": "13241", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13241" } ], "weight": 0.0 }, { "disease_id": "DOID:2228", "name": "thrombocytosis", "description": "A blood platelet disease that is characterized by the presence of high platelet counts in the blood.", "url": "https://disease-ontology.org/term/DOID:2228", "evidence": [ { "id": "2228", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2228" } ], "weight": 0.0 }, { "disease_id": "DOID:4989", "name": "pancreatitis", "description": "A pancreas disease that is characterized by inflammation of the pancreas.", "url": "https://disease-ontology.org/term/DOID:4989", "evidence": [ { "id": "4989", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4989" } ], "weight": 0.0 }, { "disease_id": "DOID:784", "name": "chronic kidney disease", "description": "A kidney failure that is characterized by the gradual loss of kidney function, present for a minimum of 3 months. CKD is classified based on cause, glomerular filtration rate (GFR) category (G2-G5), and albuminuria category (A1-A3).", "url": "https://disease-ontology.org/term/DOID:784", "evidence": [ { "id": "784", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:784" } ], "weight": 0.0 }, { "disease_id": "DOID:9351", "name": "diabetes mellitus", "description": "A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.", "url": "https://disease-ontology.org/term/DOID:9351", "evidence": [ { "id": "9351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9351" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VS65", "url": "https://www.uniprot.org/uniprotkb/Q9VS65" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VS65", "url": "https://www.uniprot.org/uniprotkb/Q9VS65" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VS65", "url": "https://www.uniprot.org/uniprotkb/Q9VS65" } ], "pmid": "" }, { "name": "metallocarboxypeptidase activity", "id": "GO:0004181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004181", "evidence": [ { "database": "UniProtKB", "id": "Q9VS65", "url": "https://www.uniprot.org/uniprotkb/Q9VS65" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VS65-1" }, { "uniprot_canonical_ac": "Q9VS81-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VS81", "url": "https://www.uniprot.org/uniprotkb/Q9VS81" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 197, "chemical_mass": 21791.0, "gene_names": "Dmel\\CG7548;CG7548;Dmel\\CG7548;Dmel_CG7548", "protein_name": "", "disease": [], "molecular_function": [ { "name": "structural constituent of cuticle", "id": "GO:0042302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042302", "evidence": [ { "database": "UniProtKB", "id": "Q9VS81", "url": "https://www.uniprot.org/uniprotkb/Q9VS81" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VS81-1" }, { "uniprot_canonical_ac": "Q9VS91-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VS91", "url": "https://www.uniprot.org/uniprotkb/Q9VS91" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 728, "chemical_mass": 84012.0, "gene_names": "t-Grip84;CG7716;Dmel\\CG7716;Dmel_CG7716;t-Grip84", "protein_name": "Gamma-tubulin complex component", "disease": [ { "disease_id": "DOID:0081266", "name": "complex cortical dysplasia with other brain malformations 15", "description": "A cortical dysplasia with other brain malformation that is characterized by progressive microcephaly associated with abnormal facial features, hypotonia, and variable global developmental delay with impaired intellectual development and that has_material_basis_in homozygous or compound heterozygous mutation in the TUBGCP2 gene on chromosome 10q26.", "url": "https://disease-ontology.org/term/DOID:0081266", "evidence": [ { "id": "0081266", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081266" } ], "weight": 0.0 } ], "biological_process": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "Q9VS91", "url": "https://www.uniprot.org/uniprotkb/Q9VS91" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "Q9VS91", "url": "https://www.uniprot.org/uniprotkb/Q9VS91" } ], "pmid": "" }, { "name": "microtubule nucleation", "id": "GO:0007020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007020", "evidence": [ { "database": "UniProtKB", "id": "Q9VS91", "url": "https://www.uniprot.org/uniprotkb/Q9VS91" } ], "pmid": "" }, { "name": "spindle assembly", "id": "GO:0051225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051225", "evidence": [ { "database": "UniProtKB", "id": "Q9VS91", "url": "https://www.uniprot.org/uniprotkb/Q9VS91" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "Q9VS91", "url": "https://www.uniprot.org/uniprotkb/Q9VS91" } ], "pmid": "" }, { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "Q9VS91", "url": "https://www.uniprot.org/uniprotkb/Q9VS91" } ], "pmid": "" } ], "cellular_component": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "Q9VS91", "url": "https://www.uniprot.org/uniprotkb/Q9VS91" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "Q9VS91", "url": "https://www.uniprot.org/uniprotkb/Q9VS91" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VS91", "url": "https://www.uniprot.org/uniprotkb/Q9VS91" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q9VS91", "url": "https://www.uniprot.org/uniprotkb/Q9VS91" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "Q9VS91", "url": "https://www.uniprot.org/uniprotkb/Q9VS91" } ], "pmid": "" }, { "name": "gamma-tubulin complex", "id": "GO:0000930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000930", "evidence": [ { "database": "UniProtKB", "id": "Q9VS91", "url": "https://www.uniprot.org/uniprotkb/Q9VS91" } ], "pmid": "" } ], "molecular_function": [ { "name": "gamma-tubulin binding", "id": "GO:0043015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043015", "evidence": [ { "database": "UniProtKB", "id": "Q9VS91", "url": "https://www.uniprot.org/uniprotkb/Q9VS91" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VS91-1" }, { "uniprot_canonical_ac": "Q9VSJ2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 262, "chemical_mass": 28375.0, "gene_names": "Jon66Cii;66C;CCG7170;CG7170;Dmel\\CG7170;Dmel_CG7170;Jon66CII;Jon66Cii;Jon66C;SP165", "protein_name": "trypsin", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ2" } ], "pmid": "" }, { "name": "serine hydrolase activity", "id": "GO:0017171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017171", "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ2" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ2" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ2" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VSJ2-1" }, { "uniprot_canonical_ac": "Q9VSQ2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VSQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VSQ2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 401, "chemical_mass": 43433.0, "gene_names": "Dmel\\CG13310;CG13310;Dmel\\CG13310;Dmel_CG13310", "protein_name": "CUB domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VSQ2-1", "start_pos": "177", "end_pos": "177", "site_lbl": "Thr177", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 177, "start_aa": "Thr", "end_pos": 177, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr177", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VSQ2-1" }, { "uniprot_canonical_ac": "Q9VSR8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VSR8", "url": "https://www.uniprot.org/uniprotkb/Q9VSR8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 476, "chemical_mass": 54036.0, "gene_names": "Dmel\\CG5653;CG5653;Dmel\\CG5653;Dmel_CG5653", "protein_name": "Amine oxidase domain-containing protein", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VSR8", "url": "https://www.uniprot.org/uniprotkb/Q9VSR8" } ], "pmid": "" } ], "molecular_function": [ { "name": "polyamine oxidase activity", "id": "GO:0046592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046592", "evidence": [ { "database": "UniProtKB", "id": "Q9VSR8", "url": "https://www.uniprot.org/uniprotkb/Q9VSR8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VSR8-1" }, { "uniprot_canonical_ac": "Q9VT14-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VT14", "url": "https://www.uniprot.org/uniprotkb/Q9VT14" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 379, "chemical_mass": 44527.0, "gene_names": "bs17c12.y1;CG3222;Dmel\\CG3222;Dmel_CG3222;NEST:bs17c12;bs17c12.y1", "protein_name": "MORN repeat-containing protein 5", "disease": [], "cellular_component": [ { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "Q9VT14", "url": "https://www.uniprot.org/uniprotkb/Q9VT14" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VT14-1", "start_pos": "130", "end_pos": "130", "site_lbl": "Thr130", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 130, "start_aa": "Thr", "end_pos": 130, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr130", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VT14-1" }, { "uniprot_canonical_ac": "Q9VT23-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VT23", "url": "https://www.uniprot.org/uniprotkb/Q9VT23" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 259, "chemical_mass": 27841.0, "gene_names": "SP170;CG8329;Dmel\\CG8329;Dmel_CG8329;SP170", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "Q9VT23", "url": "https://www.uniprot.org/uniprotkb/Q9VT23" } ], "pmid": "" }, { "name": "serine hydrolase activity", "id": "GO:0017171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017171", "evidence": [ { "database": "UniProtKB", "id": "Q9VT23", "url": "https://www.uniprot.org/uniprotkb/Q9VT23" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VT23", "url": "https://www.uniprot.org/uniprotkb/Q9VT23" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VT23", "url": "https://www.uniprot.org/uniprotkb/Q9VT23" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q9VT23", "url": "https://www.uniprot.org/uniprotkb/Q9VT23" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VT23-1" }, { "uniprot_canonical_ac": "Q9VT29-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VT29", "url": "https://www.uniprot.org/uniprotkb/Q9VT29" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 300, "chemical_mass": 33580.0, "gene_names": "Mpped;CG16717;Dmel\\CG16717;Dmel_CG16717", "protein_name": "Calcineurin-like phosphoesterase domain-containing protein", "disease": [], "molecular_function": [ { "name": "phosphoric diester hydrolase activity", "id": "GO:0008081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008081", "evidence": [ { "database": "UniProtKB", "id": "Q9VT29", "url": "https://www.uniprot.org/uniprotkb/Q9VT29" } ], "pmid": "" }, { "name": "cyclic-nucleotide phosphodiesterase activity", "id": "GO:0004112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004112", "evidence": [ { "database": "UniProtKB", "id": "Q9VT29", "url": "https://www.uniprot.org/uniprotkb/Q9VT29" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VT29-1" }, { "uniprot_canonical_ac": "Q9VT95-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VT95", "url": "https://www.uniprot.org/uniprotkb/Q9VT95" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 574, "chemical_mass": 66716.0, "gene_names": "Ir67b;67b;CG12303;DmelIR67b;Dmel\\CG12303;Dmel_CG12303;IR67b;Ir67b", "protein_name": "", "disease": [], "biological_process": [ { "name": "detection of chemical stimulus", "id": "GO:0009593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009593", "evidence": [ { "database": "UniProtKB", "id": "Q9VT95", "url": "https://www.uniprot.org/uniprotkb/Q9VT95" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VT95", "url": "https://www.uniprot.org/uniprotkb/Q9VT95" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VT95", "url": "https://www.uniprot.org/uniprotkb/Q9VT95" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "Q9VT95", "url": "https://www.uniprot.org/uniprotkb/Q9VT95" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VT95-1" }, { "uniprot_canonical_ac": "X2JGL7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JGL7", "url": "https://www.uniprot.org/uniprotkb/X2JGL7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 458, "chemical_mass": 52178.0, "gene_names": "Sms;CG4300;Dmel\\CG4300;Dmel_CG4300;Sms;anon-WO0118547.387;dSms;sms", "protein_name": "", "disease": [ { "disease_id": "DOID:0060802", "name": "syndromic X-linked intellectual disability Snyder type", "description": "A syndromic X-linked intellectual disability characterized by mild to profound intellectual disability, facial asymmetry, marfanoid habitus, asthenic habitus, unsteady gait, thickened lower lip, nasal dysarthic speech, narrow or cleft palate, osteoporosis, kyphoscoliosis, long great toes, short stature, pectus carinatum, and myopia that has_material_basis_in mutation in the SMS gene on chromosome Xp22.", "url": "https://disease-ontology.org/term/DOID:0060802", "evidence": [ { "id": "0060802", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060802" } ], "weight": 0.0 }, { "disease_id": "DOID:2030", "name": "anxiety disorder", "description": "A cognitive disorder that involves an excessive, irrational dread of everyday situations.", "url": "https://disease-ontology.org/term/DOID:2030", "evidence": [ { "id": "2030", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2030" } ], "weight": 0.0 } ], "biological_process": [ { "name": "spermine biosynthetic process", "id": "GO:0006597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006597", "evidence": [ { "database": "UniProtKB", "id": "X2JGL7", "url": "https://www.uniprot.org/uniprotkb/X2JGL7" } ], "pmid": "" } ], "molecular_function": [ { "name": "spermine synthase activity", "id": "GO:0016768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016768", "evidence": [ { "database": "UniProtKB", "id": "X2JGL7", "url": "https://www.uniprot.org/uniprotkb/X2JGL7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "X2JGL7-1" }, { "uniprot_canonical_ac": "Q9VU11-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VU11", "url": "https://www.uniprot.org/uniprotkb/Q9VU11" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 697, "chemical_mass": 78942.0, "gene_names": "Dmel\\CG10969;CG10969;Dmel\\CG10969;Dmel_CG10969", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VU11-1" }, { "uniprot_canonical_ac": "Q9VU22-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VU22", "url": "https://www.uniprot.org/uniprotkb/Q9VU22" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1371, "chemical_mass": 151087.0, "gene_names": "Dmel\\CG14120;CG14120;Dmel\\CG14120;Dmel_CG14120", "protein_name": "DNA/RNA non-specific endonuclease domain-containing protein", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VU22", "url": "https://www.uniprot.org/uniprotkb/Q9VU22" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q9VU22", "url": "https://www.uniprot.org/uniprotkb/Q9VU22" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VU22", "url": "https://www.uniprot.org/uniprotkb/Q9VU22" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "Q9VU22", "url": "https://www.uniprot.org/uniprotkb/Q9VU22" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "Q9VU22", "url": "https://www.uniprot.org/uniprotkb/Q9VU22" } ], "pmid": "" }, { "name": "single-stranded DNA endodeoxyribonuclease activity", "id": "GO:0000014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000014", "evidence": [ { "database": "UniProtKB", "id": "Q9VU22", "url": "https://www.uniprot.org/uniprotkb/Q9VU22" } ], "pmid": "" } ], "biological_process": [ { "name": "apoptotic DNA fragmentation", "id": "GO:0006309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006309", "evidence": [ { "database": "UniProtKB", "id": "Q9VU22", "url": "https://www.uniprot.org/uniprotkb/Q9VU22" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VU22-1" }, { "uniprot_canonical_ac": "Q9VUJ7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VUJ7", "url": "https://www.uniprot.org/uniprotkb/Q9VUJ7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 167, "chemical_mass": 19103.0, "gene_names": "Dmel\\CG18581;CG18581;Dmel\\CG18581;Dmel_CG18581", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VUJ7-1" }, { "uniprot_canonical_ac": "Q9VV12-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VV12", "url": "https://www.uniprot.org/uniprotkb/Q9VV12" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 93, "chemical_mass": 9445.0, "gene_names": "Dmel\\CG13066;CG13066;Dmel\\CG13066;Dmel_CG13066", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VV12-1" }, { "uniprot_canonical_ac": "Q9VV22-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VV22", "url": "https://www.uniprot.org/uniprotkb/Q9VV22" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 113, "chemical_mass": 12472.0, "gene_names": "Dmel\\CG4982;CG4982;Dmel\\CG4982;Dmel_CG4982", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VV22-1" }, { "uniprot_canonical_ac": "Q9VV31-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VV31", "url": "https://www.uniprot.org/uniprotkb/Q9VV31" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 155, "chemical_mass": 15844.0, "gene_names": "Dmel\\CG13059;CG13059;Dmel\\CG13059;Dmel_CG13059", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VV31-1" }, { "uniprot_canonical_ac": "Q9VV94-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VV94", "url": "https://www.uniprot.org/uniprotkb/Q9VV94" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 122, "chemical_mass": 12353.0, "gene_names": "Dmel\\CG13031;CG13031;Dmel\\CG13031;Dmel_CG13031", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VV94-1" }, { "uniprot_canonical_ac": "Q9VVA9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVA9", "url": "https://www.uniprot.org/uniprotkb/Q9VVA9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1734, "chemical_mass": 197109.0, "gene_names": "Zcchc7;CG9715;Dmel\\CG9715;Dmel_CG9715;Zcchc7;dZcchc7", "protein_name": "Zinc finger CCHC domain-containing protein 7", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA9", "url": "https://www.uniprot.org/uniprotkb/Q9VVA9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA9", "url": "https://www.uniprot.org/uniprotkb/Q9VVA9" } ], "pmid": "" } ], "biological_process": [ { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA9", "url": "https://www.uniprot.org/uniprotkb/Q9VVA9" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent rRNA catabolic process", "id": "GO:0071035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071035", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA9", "url": "https://www.uniprot.org/uniprotkb/Q9VVA9" } ], "pmid": "" }, { "name": "TRAMP-dependent tRNA surveillance pathway", "id": "GO:0071038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071038", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA9", "url": "https://www.uniprot.org/uniprotkb/Q9VVA9" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent snoRNA catabolic process", "id": "GO:0071036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071036", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA9", "url": "https://www.uniprot.org/uniprotkb/Q9VVA9" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent snRNA catabolic process", "id": "GO:0071037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071037", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA9", "url": "https://www.uniprot.org/uniprotkb/Q9VVA9" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent CUT catabolic process", "id": "GO:0071039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071039", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA9", "url": "https://www.uniprot.org/uniprotkb/Q9VVA9" } ], "pmid": "" }, { "name": "nuclear mRNA surveillance of mRNA 3'-end processing", "id": "GO:0071031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071031", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA9", "url": "https://www.uniprot.org/uniprotkb/Q9VVA9" } ], "pmid": "" } ], "cellular_component": [ { "name": "TRAMP complex", "id": "GO:0031499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031499", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA9", "url": "https://www.uniprot.org/uniprotkb/Q9VVA9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VVA9-1", "start_pos": "1526", "end_pos": "1526", "site_lbl": "Thr1526", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1526, "start_aa": "Thr", "end_pos": 1526, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1526", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VVA9-1" }, { "uniprot_canonical_ac": "Q9VVF1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVF1", "url": "https://www.uniprot.org/uniprotkb/Q9VVF1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 550, "chemical_mass": 64804.0, "gene_names": "Dmel\\CG13724;CG13724;Dmel\\CG13724;Dmel_CG13724", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VVF1-1", "start_pos": "348", "end_pos": "348", "site_lbl": "Thr348", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 348, "start_aa": "Thr", "end_pos": 348, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr348", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VVF1", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VVF1" } ] } ] }, { "uniprot_canonical_ac": "Q9VVF1-1", "start_pos": "350", "end_pos": "350", "site_lbl": "Thr350", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 350, "start_aa": "Thr", "end_pos": 350, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr350", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VVF1", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VVF1" } ] } ] } ], "record_id": "Q9VVF1-1" }, { "uniprot_canonical_ac": "Q9VVF5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVF5", "url": "https://www.uniprot.org/uniprotkb/Q9VVF5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 302, "chemical_mass": 31788.0, "gene_names": "Dmel\\CG13727;CG13727;Dmel\\CG13727;Dmel_CG13727", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VVF5-1", "start_pos": "273", "end_pos": "273", "site_lbl": "Thr273", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 273, "start_aa": "Thr", "end_pos": 273, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr273", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VVF5-1" }, { "uniprot_canonical_ac": "Q9VVG2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVG2", "url": "https://www.uniprot.org/uniprotkb/Q9VVG2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 792, "chemical_mass": 86568.0, "gene_names": "Dmel\\CG13731;CG13731;Dmel\\CG13731;Dmel_CG13731", "protein_name": "Proline-rich extensin-like protein EPR1", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VVG2-1", "start_pos": "268", "end_pos": "268", "site_lbl": "Thr268", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 268, "start_aa": "Thr", "end_pos": 268, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr268", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VVG2-1", "start_pos": "435", "end_pos": "435", "site_lbl": "Thr435", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 435, "start_aa": "Thr", "end_pos": 435, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr435", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VVG2-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Thr73", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 73, "start_aa": "Thr", "end_pos": 73, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr73", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VVG2-1" }, { "uniprot_canonical_ac": "Q9VVJ9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1725, "chemical_mass": 195315.0, "gene_names": "Dmel\\CG6052;CG6052;DmCG6052;Dmel_CG6052", "protein_name": "ABC transporter domain-containing protein", "disease": [ { "disease_id": "DOID:11161", "name": "neonatal respiratory failure", "description": "A respiratory failure that is characterized by inadequate gas exchange by the respiratory system in neonates.", "url": "https://disease-ontology.org/term/DOID:11161", "evidence": [ { "id": "11161", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11161" } ], "weight": 0.0 }, { "disease_id": "DOID:11162", "name": "respiratory failure", "description": "A lung disease characterized by inadequate gas exchange by the respiratory system.", "url": "https://disease-ontology.org/term/DOID:11162", "evidence": [ { "id": "11162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11162" } ], "weight": 0.0 }, { "disease_id": "DOID:12120", "name": "pulmonary alveolar proteinosis", "description": "A lung disease that is characterized by abnormal accumulation of surfactant occurs within the alveoli, interfering with gas exchange.", "url": "https://disease-ontology.org/term/DOID:12120", "evidence": [ { "id": "12120", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12120" } ], "weight": 0.0 }, { "disease_id": "DOID:12716", "name": "newborn respiratory distress syndrome", "description": "A respiratory failure that is characterized by deficiency of the surfactant coating the inner surface of the lungs, by failure of the lungs to expand and contract properly during breathing with resulting collapse, and by the accumulation of a protein-containing film lining the alveoli and their ducts.", "url": "https://disease-ontology.org/term/DOID:12716", "evidence": [ { "id": "12716", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12716" } ], "weight": 0.0 }, { "disease_id": "DOID:3082", "name": "interstitial lung disease", "description": "A lung disease that is characterized by inflammation and altered lung interstitium compromising pulmonary function and often has_symptom shortness of breath, dyspnea, and/or cough.", "url": "https://disease-ontology.org/term/DOID:3082", "evidence": [ { "id": "3082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3082" } ], "weight": 0.0 }, { "disease_id": "DOID:850", "name": "lung disease", "description": "A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide.", "url": "https://disease-ontology.org/term/DOID:850", "evidence": [ { "id": "850", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:850" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "lipid transporter activity", "id": "GO:0005319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005319", "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ9" } ], "pmid": "" }, { "name": "ATPase-coupled transmembrane transporter activity", "id": "GO:0042626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042626", "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ9" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ9" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ9" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ9" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VVJ9-1" }, { "uniprot_canonical_ac": "Q9VVM4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVM4", "url": "https://www.uniprot.org/uniprotkb/Q9VVM4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 579, "chemical_mass": 65054.0, "gene_names": "Dmel\\CG7402;CG7402;Dmel\\CG7402;Dmel_CG7402", "protein_name": "Sulfatase N-terminal domain-containing protein", "disease": [ { "disease_id": "DOID:12800", "name": "mucopolysaccharidosis VI", "description": "A mucopolysaccharidosis characterized by a deficiency of the lysosomal enzyme N-acetylgalactosamine 4-sulfatase.", "url": "https://disease-ontology.org/term/DOID:12800", "evidence": [ { "id": "12800", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12800" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM4", "url": "https://www.uniprot.org/uniprotkb/Q9VVM4" } ], "pmid": "" }, { "name": "N-acetylgalactosamine-4-sulfatase activity", "id": "GO:0003943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003943", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM4", "url": "https://www.uniprot.org/uniprotkb/Q9VVM4" } ], "pmid": "" }, { "name": "sulfuric ester hydrolase activity", "id": "GO:0008484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008484", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM4", "url": "https://www.uniprot.org/uniprotkb/Q9VVM4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VVM4-1" }, { "uniprot_canonical_ac": "Q9VVV0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVV0", "url": "https://www.uniprot.org/uniprotkb/Q9VVV0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 322, "chemical_mass": 36229.0, "gene_names": "Dmel\\CG18223;BcDNA:AT03311;CG18223;Dmel\\CG18223;Dmel_CG18223;SPH200", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VVV0", "url": "https://www.uniprot.org/uniprotkb/Q9VVV0" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VVV0", "url": "https://www.uniprot.org/uniprotkb/Q9VVV0" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q9VVV0", "url": "https://www.uniprot.org/uniprotkb/Q9VVV0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VVV0-1" }, { "uniprot_canonical_ac": "Q9VVW7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVW7", "url": "https://www.uniprot.org/uniprotkb/Q9VVW7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 221, "chemical_mass": 25632.0, "gene_names": "CNPYb;CG11577;CNPYb;Dmel\\CG11577;Dmel_CG11577;anon-WO0118547.323", "protein_name": "", "disease": [ { "disease_id": "DOID:0080432", "name": "developmental and epileptic encephalopathy 60", "description": "A developmental and epileptic encephalopathy characterized by onset of infantile spasms, seizures, or myoclonus in the first months of life, hypsarrhythmia on EEG, and severe global developmental delay that has_material_basis_in homozygous or compound heterozygous mutation in the CNPY3 gene on chromosome 6p.", "url": "https://disease-ontology.org/term/DOID:0080432", "evidence": [ { "id": "0080432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080432" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q9VVW7", "url": "https://www.uniprot.org/uniprotkb/Q9VVW7" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "Q9VVW7", "url": "https://www.uniprot.org/uniprotkb/Q9VVW7" } ], "pmid": "" } ], "biological_process": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "Q9VVW7", "url": "https://www.uniprot.org/uniprotkb/Q9VVW7" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein folding chaperone", "id": "GO:0044183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044183", "evidence": [ { "database": "UniProtKB", "id": "Q9VVW7", "url": "https://www.uniprot.org/uniprotkb/Q9VVW7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VVW7-1" }, { "uniprot_canonical_ac": "Q9VVX9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVX9", "url": "https://www.uniprot.org/uniprotkb/Q9VVX9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 289, "chemical_mass": 32032.0, "gene_names": "SPH199;CG14088;Dmel\\CG14088;Dmel_CG14088;SPH199", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VVX9", "url": "https://www.uniprot.org/uniprotkb/Q9VVX9" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VVX9", "url": "https://www.uniprot.org/uniprotkb/Q9VVX9" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q9VVX9", "url": "https://www.uniprot.org/uniprotkb/Q9VVX9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VVX9-1" }, { "uniprot_canonical_ac": "R9PY60-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "R9PY60", "url": "https://www.uniprot.org/uniprotkb/R9PY60" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1278, "chemical_mass": 139737.0, "gene_names": "CG14091;CG9600;CG14090;CG14091;CG14092;CG32206;CG9600;Dmel\\CG32206;Dmel_CG32206", "protein_name": "CUB domain-containing protein", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "R9PY60", "url": "https://www.uniprot.org/uniprotkb/R9PY60" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "R9PY60-1", "start_pos": "258", "end_pos": "258", "site_lbl": "Thr258", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 258, "start_aa": "Thr", "end_pos": 258, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr258", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "R9PY60-1" }, { "uniprot_canonical_ac": "Q9VVZ4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVZ4", "url": "https://www.uniprot.org/uniprotkb/Q9VVZ4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 162, "chemical_mass": 15946.0, "gene_names": "Dmel\\CG14095;CG14095;Dmel\\CG14095;Dmel_CG14095", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VVZ4-1" }, { "uniprot_canonical_ac": "Q9VW52-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VW52", "url": "https://www.uniprot.org/uniprotkb/Q9VW52" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 598, "chemical_mass": 67382.0, "gene_names": "Prp3;CG7757;Dmel\\CG7757;Dmel_CG7757;PRPF3;Prp3;dPrp3;prp3", "protein_name": "", "disease": [ { "disease_id": "DOID:0110356", "name": "retinitis pigmentosa 18", "description": "A retinitis pigmentosa that has_material_basis_in mutation in the PRPF3 gene on chromosome 1q21.", "url": "https://disease-ontology.org/term/DOID:0110356", "evidence": [ { "id": "0110356", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110356" } ], "weight": 0.0 }, { "disease_id": "DOID:10584", "name": "retinitis pigmentosa", "description": "A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.", "url": "https://disease-ontology.org/term/DOID:10584", "evidence": [ { "id": "10584", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10584" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9VW52", "url": "https://www.uniprot.org/uniprotkb/Q9VW52" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VW52", "url": "https://www.uniprot.org/uniprotkb/Q9VW52" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "Q9VW52", "url": "https://www.uniprot.org/uniprotkb/Q9VW52" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "Q9VW52", "url": "https://www.uniprot.org/uniprotkb/Q9VW52" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "Q9VW52", "url": "https://www.uniprot.org/uniprotkb/Q9VW52" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q9VW52", "url": "https://www.uniprot.org/uniprotkb/Q9VW52" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VW52-1" }, { "uniprot_canonical_ac": "Q9VW57-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VW57", "url": "https://www.uniprot.org/uniprotkb/Q9VW57" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 460, "chemical_mass": 47724.0, "gene_names": "Grasp65;CG7809;Dmel\\CG7809;Dmel_CG7809;GRASP65;GRASP;Grasp65;dGRASP;dGrasp65;dGrasp;dgrasp", "protein_name": "", "disease": [ { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "apical cortex", "id": "GO:0045179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045179", "evidence": [ { "database": "UniProtKB", "id": "Q9VW57", "url": "https://www.uniprot.org/uniprotkb/Q9VW57" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q9VW57", "url": "https://www.uniprot.org/uniprotkb/Q9VW57" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q9VW57", "url": "https://www.uniprot.org/uniprotkb/Q9VW57" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q9VW57", "url": "https://www.uniprot.org/uniprotkb/Q9VW57" } ], "pmid": "" }, { "name": "Golgi-associated vesicle", "id": "GO:0005798", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005798", "evidence": [ { "database": "UniProtKB", "id": "Q9VW57", "url": "https://www.uniprot.org/uniprotkb/Q9VW57" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VW57", "url": "https://www.uniprot.org/uniprotkb/Q9VW57" } ], "pmid": "" }, { "name": "Golgi stack", "id": "GO:0005795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005795", "evidence": [ { "database": "UniProtKB", "id": "Q9VW57", "url": "https://www.uniprot.org/uniprotkb/Q9VW57" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VW57", "url": "https://www.uniprot.org/uniprotkb/Q9VW57" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of lipid storage", "id": "GO:0010884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010884", "evidence": [ { "database": "UniProtKB", "id": "Q9VW57", "url": "https://www.uniprot.org/uniprotkb/Q9VW57" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "Q9VW57", "url": "https://www.uniprot.org/uniprotkb/Q9VW57" } ], "pmid": "" }, { "name": "wing disc morphogenesis", "id": "GO:0007472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007472", "evidence": [ { "database": "UniProtKB", "id": "Q9VW57", "url": "https://www.uniprot.org/uniprotkb/Q9VW57" } ], "pmid": "" }, { "name": "morphogenesis of follicular epithelium", "id": "GO:0016333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016333", "evidence": [ { "database": "UniProtKB", "id": "Q9VW57", "url": "https://www.uniprot.org/uniprotkb/Q9VW57" } ], "pmid": "" }, { "name": "regulation of imaginal disc-derived wing size", "id": "GO:0044719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044719", "evidence": [ { "database": "UniProtKB", "id": "Q9VW57", "url": "https://www.uniprot.org/uniprotkb/Q9VW57" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VW57-1" }, { "uniprot_canonical_ac": "Q9VW81-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VW81", "url": "https://www.uniprot.org/uniprotkb/Q9VW81" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 353, "chemical_mass": 39713.0, "gene_names": "obst-J;CG7348;Dmel\\CG7348;Dmel_CG7348;Obst-J;anon-EST:ParkEST360;obst-J", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VW81", "url": "https://www.uniprot.org/uniprotkb/Q9VW81" } ], "pmid": "" }, { "name": "chitin-based extracellular matrix", "id": "GO:0062129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062129", "evidence": [ { "database": "UniProtKB", "id": "Q9VW81", "url": "https://www.uniprot.org/uniprotkb/Q9VW81" } ], "pmid": "" }, { "name": "external encapsulating structure", "id": "GO:0030312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030312", "evidence": [ { "database": "UniProtKB", "id": "Q9VW81", "url": "https://www.uniprot.org/uniprotkb/Q9VW81" } ], "pmid": "" } ], "molecular_function": [ { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "Q9VW81", "url": "https://www.uniprot.org/uniprotkb/Q9VW81" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VW81-1" }, { "uniprot_canonical_ac": "Q9VWC5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWC5", "url": "https://www.uniprot.org/uniprotkb/Q9VWC5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 158, "chemical_mass": 17569.0, "gene_names": "SkpD;BcDNA:AT18217;CG12700;Dmel\\CG12700;Dmel_CG12700;SkpD;Skp;dskpD;skpD", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC5", "url": "https://www.uniprot.org/uniprotkb/Q9VWC5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC5", "url": "https://www.uniprot.org/uniprotkb/Q9VWC5" } ], "pmid": "" }, { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC5", "url": "https://www.uniprot.org/uniprotkb/Q9VWC5" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC5", "url": "https://www.uniprot.org/uniprotkb/Q9VWC5" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC5", "url": "https://www.uniprot.org/uniprotkb/Q9VWC5" } ], "pmid": "" }, { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC5", "url": "https://www.uniprot.org/uniprotkb/Q9VWC5" } ], "pmid": "" } ], "molecular_function": [ { "name": "cullin family protein binding", "id": "GO:0097602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097602", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC5", "url": "https://www.uniprot.org/uniprotkb/Q9VWC5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VWC5-1" }, { "uniprot_canonical_ac": "Q9VWG5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWG5", "url": "https://www.uniprot.org/uniprotkb/Q9VWG5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 724, "chemical_mass": 80808.0, "gene_names": "Dmel\\CG14219;CG14219;Dmel\\CG14219;Dmel_CG14219", "protein_name": "Nose resistant-to-fluoxetine protein N-terminal domain-containing protein", "disease": [], "molecular_function": [ { "name": "acyltransferase activity, transferring groups other than amino-acyl groups", "id": "GO:0016747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016747", "evidence": [ { "database": "UniProtKB", "id": "Q9VWG5", "url": "https://www.uniprot.org/uniprotkb/Q9VWG5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VWG5-1" }, { "uniprot_canonical_ac": "Q9VWH9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWH9", "url": "https://www.uniprot.org/uniprotkb/Q9VWH9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 323, "chemical_mass": 39067.0, "gene_names": "Snrnp48;CG12204;Dmel\\CG12204;Dmel_CG12204", "protein_name": "", "disease": [], "cellular_component": [ { "name": "U11/U12 snRNP", "id": "GO:0034693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034693", "evidence": [ { "database": "UniProtKB", "id": "Q9VWH9", "url": "https://www.uniprot.org/uniprotkb/Q9VWH9" } ], "pmid": "" }, { "name": "U12-type spliceosomal complex", "id": "GO:0005689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005689", "evidence": [ { "database": "UniProtKB", "id": "Q9VWH9", "url": "https://www.uniprot.org/uniprotkb/Q9VWH9" } ], "pmid": "" } ], "biological_process": [ { "name": "alternative mRNA splicing, via spliceosome", "id": "GO:0000380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000380", "evidence": [ { "database": "UniProtKB", "id": "Q9VWH9", "url": "https://www.uniprot.org/uniprotkb/Q9VWH9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VWH9-1" }, { "uniprot_canonical_ac": "Q9VWP7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWP7", "url": "https://www.uniprot.org/uniprotkb/Q9VWP7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 352, "chemical_mass": 40234.0, "gene_names": "Dmel\\CG7101;CG7101;Dmel\\CG7101;Dmel_CG7101", "protein_name": "C2H2-type domain-containing protein", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP7", "url": "https://www.uniprot.org/uniprotkb/Q9VWP7" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP7", "url": "https://www.uniprot.org/uniprotkb/Q9VWP7" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP7", "url": "https://www.uniprot.org/uniprotkb/Q9VWP7" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP7", "url": "https://www.uniprot.org/uniprotkb/Q9VWP7" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP7", "url": "https://www.uniprot.org/uniprotkb/Q9VWP7" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP7", "url": "https://www.uniprot.org/uniprotkb/Q9VWP7" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP7", "url": "https://www.uniprot.org/uniprotkb/Q9VWP7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VWP7-1" }, { "uniprot_canonical_ac": "Q9VWT5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWT5", "url": "https://www.uniprot.org/uniprotkb/Q9VWT5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 250, "chemical_mass": 27976.0, "gene_names": "Xrcc2;CG6318;Dm CG6318;Dmel\\CG6318;Dmel_CG6318;Rad51D;XRCC2;Xrcc2;dmRad51D", "protein_name": "", "disease": [ { "disease_id": "DOID:0080874", "name": "primary ovarian insufficiency 17", "description": "A primary ovarian insufficiency that is characterized by early cessation of menses after initial menarche, with small ovaries and uterus and that has_material_basis_in homozygous mutation in the XRCC2 gene on chromosome 7q36.", "url": "https://disease-ontology.org/term/DOID:0080874", "evidence": [ { "id": "0080874", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080874" } ], "weight": 0.0 }, { "disease_id": "DOID:0111085", "name": "Fanconi anemia complementation group U", "description": "A Fanconi anemia that has_material_basis_in homozygous mutation in the XRCC2 gene on chromosome 7q36.", "url": "https://disease-ontology.org/term/DOID:0111085", "evidence": [ { "id": "0111085", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111085" } ], "weight": 0.0 }, { "disease_id": "DOID:0112272", "name": "spermatogenic failure 50", "description": "A spermatogenic failure that is characterized by azoospermia resulting from meiotic arrest at prophase I that has_material_basis_in homozygous or compound heterozygous mutation in the XRCC2 gene on chromosome 7q36.1.", "url": "https://disease-ontology.org/term/DOID:0112272", "evidence": [ { "id": "0112272", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112272" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "Q9VWT5", "url": "https://www.uniprot.org/uniprotkb/Q9VWT5" } ], "pmid": "" }, { "name": "replication fork", "id": "GO:0005657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005657", "evidence": [ { "database": "UniProtKB", "id": "Q9VWT5", "url": "https://www.uniprot.org/uniprotkb/Q9VWT5" } ], "pmid": "" }, { "name": "Rad51B-Rad51C-Rad51D-XRCC2 complex", "id": "GO:0033063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033063", "evidence": [ { "database": "UniProtKB", "id": "Q9VWT5", "url": "https://www.uniprot.org/uniprotkb/Q9VWT5" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q9VWT5", "url": "https://www.uniprot.org/uniprotkb/Q9VWT5" } ], "pmid": "" }, { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "Q9VWT5", "url": "https://www.uniprot.org/uniprotkb/Q9VWT5" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "Q9VWT5", "url": "https://www.uniprot.org/uniprotkb/Q9VWT5" } ], "pmid": "" }, { "name": "DNA strand invasion", "id": "GO:0042148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042148", "evidence": [ { "database": "UniProtKB", "id": "Q9VWT5", "url": "https://www.uniprot.org/uniprotkb/Q9VWT5" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA strand exchange activity", "id": "GO:0000150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000150", "evidence": [ { "database": "UniProtKB", "id": "Q9VWT5", "url": "https://www.uniprot.org/uniprotkb/Q9VWT5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VWT5-1" }, { "uniprot_canonical_ac": "Q9VWY5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWY5", "url": "https://www.uniprot.org/uniprotkb/Q9VWY5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 417, "chemical_mass": 48592.0, "gene_names": "Dmel\\CG7135;CG7135;Dmel\\CG7135;Dmel_CG7135;Dro32-0", "protein_name": "CHK kinase-like domain-containing protein", "disease": [], "molecular_function": [ { "name": "ecdysteroid 22-kinase activity", "id": "GO:0106389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106389", "evidence": [ { "database": "UniProtKB", "id": "Q9VWY5", "url": "https://www.uniprot.org/uniprotkb/Q9VWY5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VWY5-1" }, { "uniprot_canonical_ac": "X2JCF3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JCF3", "url": "https://www.uniprot.org/uniprotkb/X2JCF3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 581, "chemical_mass": 65859.0, "gene_names": "RhoGAP16F;CG7122;Dmel\\CG7122;Dmel_CG7122;RhoGAP16F", "protein_name": "", "disease": [], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "X2JCF3", "url": "https://www.uniprot.org/uniprotkb/X2JCF3" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "X2JCF3", "url": "https://www.uniprot.org/uniprotkb/X2JCF3" } ], "pmid": "" }, { "name": "imaginal disc-derived leg morphogenesis", "id": "GO:0007480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007480", "evidence": [ { "database": "UniProtKB", "id": "X2JCF3", "url": "https://www.uniprot.org/uniprotkb/X2JCF3" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "X2JCF3", "url": "https://www.uniprot.org/uniprotkb/X2JCF3" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "X2JCF3", "url": "https://www.uniprot.org/uniprotkb/X2JCF3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "X2JCF3", "url": "https://www.uniprot.org/uniprotkb/X2JCF3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "X2JCF3-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Thr11", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 11, "start_aa": "Thr", "end_pos": 11, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr11", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "X2JCF3-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Thr3", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 3, "start_aa": "Thr", "end_pos": 3, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "X2JCF3", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=X2JCF3" } ] } ] }, { "uniprot_canonical_ac": "X2JCF3-1", "start_pos": "451", "end_pos": "451", "site_lbl": "Thr451", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 451, "start_aa": "Thr", "end_pos": 451, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr451", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "X2JCF3-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Thr5", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 5, "start_aa": "Thr", "end_pos": 5, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr5", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "X2JCF3", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=X2JCF3" } ] } ] } ], "record_id": "X2JCF3-1" }, { "uniprot_canonical_ac": "Q9VX72-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VX72", "url": "https://www.uniprot.org/uniprotkb/Q9VX72" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 170, "chemical_mass": 18839.0, "gene_names": "Dmel\\CG32563;CG32563;CG5095;Dmel\\CG32563;Dmel_CG32563", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VX72-1" }, { "uniprot_canonical_ac": "Q9VXP8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VXP8", "url": "https://www.uniprot.org/uniprotkb/Q9VXP8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 276, "chemical_mass": 29910.0, "gene_names": "Dmel\\CG8952;CG8952;Dmel\\CG8952;Dmel_CG8952;SP52", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "Q9VXP8", "url": "https://www.uniprot.org/uniprotkb/Q9VXP8" } ], "pmid": "" }, { "name": "serine hydrolase activity", "id": "GO:0017171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017171", "evidence": [ { "database": "UniProtKB", "id": "Q9VXP8", "url": "https://www.uniprot.org/uniprotkb/Q9VXP8" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VXP8", "url": "https://www.uniprot.org/uniprotkb/Q9VXP8" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VXP8", "url": "https://www.uniprot.org/uniprotkb/Q9VXP8" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q9VXP8", "url": "https://www.uniprot.org/uniprotkb/Q9VXP8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VXP8-1" }, { "uniprot_canonical_ac": "Q9VXV3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VXV3", "url": "https://www.uniprot.org/uniprotkb/Q9VXV3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2030, "chemical_mass": 227274.0, "gene_names": "shtd;APC1/shtd;APC1;Apc1;CG9198;Dmel\\CG9198;Dmel_CG9198;SHTD;Shtd;shtd", "protein_name": "", "disease": [ { "disease_id": "DOID:2732", "name": "Rothmund-Thomson syndrome", "description": "A skin disease characterized by poikiloderma, congenital bone defects, and an increased risk of osteosarcoma in childhood and skin cancer later in life that has_material_basis_in homozygous or compound heterozygous mutation in the DNA helicase gene RECQL4 on chromosome 8q24.", "url": "https://disease-ontology.org/term/DOID:2732", "evidence": [ { "id": "2732", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2732" } ], "weight": 0.0 } ], "biological_process": [ { "name": "compound eye development", "id": "GO:0048749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048749", "evidence": [ { "database": "UniProtKB", "id": "Q9VXV3", "url": "https://www.uniprot.org/uniprotkb/Q9VXV3" } ], "pmid": "" }, { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "Q9VXV3", "url": "https://www.uniprot.org/uniprotkb/Q9VXV3" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q9VXV3", "url": "https://www.uniprot.org/uniprotkb/Q9VXV3" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "Q9VXV3", "url": "https://www.uniprot.org/uniprotkb/Q9VXV3" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q9VXV3", "url": "https://www.uniprot.org/uniprotkb/Q9VXV3" } ], "pmid": "" }, { "name": "anaphase-promoting complex-dependent catabolic process", "id": "GO:0031145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031145", "evidence": [ { "database": "UniProtKB", "id": "Q9VXV3", "url": "https://www.uniprot.org/uniprotkb/Q9VXV3" } ], "pmid": "" }, { "name": "protein K11-linked ubiquitination", "id": "GO:0070979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070979", "evidence": [ { "database": "UniProtKB", "id": "Q9VXV3", "url": "https://www.uniprot.org/uniprotkb/Q9VXV3" } ], "pmid": "" }, { "name": "metaphase/anaphase transition of mitotic cell cycle", "id": "GO:0007091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007091", "evidence": [ { "database": "UniProtKB", "id": "Q9VXV3", "url": "https://www.uniprot.org/uniprotkb/Q9VXV3" } ], "pmid": "" } ], "molecular_function": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "Q9VXV3", "url": "https://www.uniprot.org/uniprotkb/Q9VXV3" } ], "pmid": "" } ], "cellular_component": [ { "name": "anaphase-promoting complex", "id": "GO:0005680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005680", "evidence": [ { "database": "UniProtKB", "id": "Q9VXV3", "url": "https://www.uniprot.org/uniprotkb/Q9VXV3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VXV3-1" }, { "uniprot_canonical_ac": "Q9VY14-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VY14", "url": "https://www.uniprot.org/uniprotkb/Q9VY14" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 201, "chemical_mass": 23633.0, "gene_names": "Dmel\\CG14410;CG14410;Dmel\\CG14410;Dmel_CG14410", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VY14-1" }, { "uniprot_canonical_ac": "Q9VY41-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VY41", "url": "https://www.uniprot.org/uniprotkb/Q9VY41" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 154, "chemical_mass": 17937.0, "gene_names": "Dmel\\CG13404;CG13404;Dmel\\CG13404;Dmel_CG13404", "protein_name": "Plasminogen receptor (KT)", "disease": [], "biological_process": [ { "name": "positive regulation of plasminogen activation", "id": "GO:0010756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010756", "evidence": [ { "database": "UniProtKB", "id": "Q9VY41", "url": "https://www.uniprot.org/uniprotkb/Q9VY41" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VY41", "url": "https://www.uniprot.org/uniprotkb/Q9VY41" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VY41", "url": "https://www.uniprot.org/uniprotkb/Q9VY41" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VY41-1" }, { "uniprot_canonical_ac": "Q9VY47-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VY47", "url": "https://www.uniprot.org/uniprotkb/Q9VY47" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1280, "chemical_mass": 143567.0, "gene_names": "CG1846;CG1846;CG33248;CG33249;CG42271;Dmel\\CG42271;Dmel_CG42271;FBgn0259166;INPP4A", "protein_name": "phosphatidylinositol-3,4-bisphosphate 4-phosphatase", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VY47", "url": "https://www.uniprot.org/uniprotkb/Q9VY47" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity", "id": "GO:0016316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016316", "evidence": [ { "database": "UniProtKB", "id": "Q9VY47", "url": "https://www.uniprot.org/uniprotkb/Q9VY47" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VY47-1" }, { "uniprot_canonical_ac": "Q9VY62-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VY62", "url": "https://www.uniprot.org/uniprotkb/Q9VY62" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 186, "chemical_mass": 19416.0, "gene_names": "Dmel\\CG1368;CG1368;Dmel\\CG1368;Dmel_CG1368", "protein_name": "Cuticle protein 16.5", "disease": [], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "Q9VY62", "url": "https://www.uniprot.org/uniprotkb/Q9VY62" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q9VY62", "url": "https://www.uniprot.org/uniprotkb/Q9VY62" } ], "pmid": "" } ], "cellular_component": [ { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "Q9VY62", "url": "https://www.uniprot.org/uniprotkb/Q9VY62" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VY62-1" }, { "uniprot_canonical_ac": "Q9VY83-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VY83", "url": "https://www.uniprot.org/uniprotkb/Q9VY83" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 392, "chemical_mass": 44493.0, "gene_names": "Galml2;CG10996;Dmel\\CG10996;Dmel_CG10996", "protein_name": "Galactose mutarotase", "disease": [ { "disease_id": "DOID:0060969", "name": "galactosemia 4", "description": "A galactosemia characterized by persistent congenital galactosemia due to deficiency of the enzyme galactose mutarotase that has_material_basis_in homozygous or compound heterozygous mutation in the GALM gene on chromosome 2p22.", "url": "https://disease-ontology.org/term/DOID:0060969", "evidence": [ { "id": "0060969", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060969" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VY83", "url": "https://www.uniprot.org/uniprotkb/Q9VY83" } ], "pmid": "" } ], "molecular_function": [ { "name": "catalytic activity", "id": "GO:0003824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003824", "evidence": [ { "database": "UniProtKB", "id": "Q9VY83", "url": "https://www.uniprot.org/uniprotkb/Q9VY83" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "Q9VY83", "url": "https://www.uniprot.org/uniprotkb/Q9VY83" } ], "pmid": "" } ], "biological_process": [ { "name": "galactose metabolic process", "id": "GO:0006012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006012", "evidence": [ { "database": "UniProtKB", "id": "Q9VY83", "url": "https://www.uniprot.org/uniprotkb/Q9VY83" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VY83-1" }, { "uniprot_canonical_ac": "Q9VYE0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VYE0", "url": "https://www.uniprot.org/uniprotkb/Q9VYE0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 377, "chemical_mass": 41301.0, "gene_names": "dmrt11E;CG15749;Dmel\\CG15749;Dmel_CG15749;Dmrt11E;dmrt11E;dmrt11", "protein_name": "", "disease": [ { "disease_id": "DOID:14227", "name": "azoospermia", "description": "A male infertility disease characterized by the absence of any measurable level of sperm in semen.", "url": "https://disease-ontology.org/term/DOID:14227", "evidence": [ { "id": "14227", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14227" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VYE0", "url": "https://www.uniprot.org/uniprotkb/Q9VYE0" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q9VYE0", "url": "https://www.uniprot.org/uniprotkb/Q9VYE0" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "Q9VYE0", "url": "https://www.uniprot.org/uniprotkb/Q9VYE0" } ], "pmid": "" }, { "name": "sex differentiation", "id": "GO:0007548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007548", "evidence": [ { "database": "UniProtKB", "id": "Q9VYE0", "url": "https://www.uniprot.org/uniprotkb/Q9VYE0" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VYE0", "url": "https://www.uniprot.org/uniprotkb/Q9VYE0" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "Q9VYE0", "url": "https://www.uniprot.org/uniprotkb/Q9VYE0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q9VYE0", "url": "https://www.uniprot.org/uniprotkb/Q9VYE0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q9VYE0", "url": "https://www.uniprot.org/uniprotkb/Q9VYE0" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "Q9VYE0", "url": "https://www.uniprot.org/uniprotkb/Q9VYE0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VYE0-1" }, { "uniprot_canonical_ac": "Q9VYH8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VYH8", "url": "https://www.uniprot.org/uniprotkb/Q9VYH8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 894, "chemical_mass": 98502.0, "gene_names": "Dmel\\CG15721;CG15721;Dmel\\CG15721;Dmel_CG15721", "protein_name": "Kazal-like domain-containing protein", "disease": [], "biological_process": [ { "name": "chorion-containing eggshell formation", "id": "GO:0007304", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007304", "evidence": [ { "database": "UniProtKB", "id": "Q9VYH8", "url": "https://www.uniprot.org/uniprotkb/Q9VYH8" } ], "pmid": "" } ], "cellular_component": [ { "name": "egg chorion", "id": "GO:0042600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042600", "evidence": [ { "database": "UniProtKB", "id": "Q9VYH8", "url": "https://www.uniprot.org/uniprotkb/Q9VYH8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VYH8-1", "start_pos": "459", "end_pos": "459", "site_lbl": "Thr459", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 459, "start_aa": "Thr", "end_pos": 459, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr459", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VYH8-1", "start_pos": "860", "end_pos": "860", "site_lbl": "Thr860", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 860, "start_aa": "Thr", "end_pos": 860, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr860", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VYH8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VYH8" } ] } ] } ], "record_id": "Q9VYH8-1" }, { "uniprot_canonical_ac": "Q9VYM7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VYM7", "url": "https://www.uniprot.org/uniprotkb/Q9VYM7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 465, "chemical_mass": 47702.0, "gene_names": "Dmel\\CG42258;Pripl4;BcDNA:RE29468;CG15926;CG17788;CG42258;Dmel\\CG42258;Dmel_CG42258;Pripl4", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VYM7", "url": "https://www.uniprot.org/uniprotkb/Q9VYM7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VYM7-1", "start_pos": "444", "end_pos": "444", "site_lbl": "Thr444", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 444, "start_aa": "Thr", "end_pos": 444, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr444", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VYM7-1" }, { "uniprot_canonical_ac": "Q9VYY5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VYY5", "url": "https://www.uniprot.org/uniprotkb/Q9VYY5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 411, "chemical_mass": 45728.0, "gene_names": "CG15194;CG15194;CG1756;CG43155;Dmel\\CG43155;Dmel_CG43155;anon-WO0109301.51;anon-WO0109301.52;anon-WO0109301.9", "protein_name": "Potassium channel domain-containing protein", "disease": [], "molecular_function": [ { "name": "outward rectifier potassium channel activity", "id": "GO:0015271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015271", "evidence": [ { "database": "UniProtKB", "id": "Q9VYY5", "url": "https://www.uniprot.org/uniprotkb/Q9VYY5" } ], "pmid": "" }, { "name": "potassium ion leak channel activity", "id": "GO:0022841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022841", "evidence": [ { "database": "UniProtKB", "id": "Q9VYY5", "url": "https://www.uniprot.org/uniprotkb/Q9VYY5" } ], "pmid": "" }, { "name": "potassium channel activity", "id": "GO:0005267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005267", "evidence": [ { "database": "UniProtKB", "id": "Q9VYY5", "url": "https://www.uniprot.org/uniprotkb/Q9VYY5" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VYY5", "url": "https://www.uniprot.org/uniprotkb/Q9VYY5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VYY5", "url": "https://www.uniprot.org/uniprotkb/Q9VYY5" } ], "pmid": "" } ], "biological_process": [ { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "Q9VYY5", "url": "https://www.uniprot.org/uniprotkb/Q9VYY5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VYY5-1" }, { "uniprot_canonical_ac": "Q9VZ47-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZ47", "url": "https://www.uniprot.org/uniprotkb/Q9VZ47" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 197, "chemical_mass": 22773.0, "gene_names": "Rab9Fa;CG2532;CG32671;DmRabX3;Dmel\\CG32671;Dmel_CG32671;Rab9Fa;RabX3", "protein_name": "", "disease": [], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ47", "url": "https://www.uniprot.org/uniprotkb/Q9VZ47" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ47", "url": "https://www.uniprot.org/uniprotkb/Q9VZ47" } ], "pmid": "" } ], "cellular_component": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ47", "url": "https://www.uniprot.org/uniprotkb/Q9VZ47" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ47", "url": "https://www.uniprot.org/uniprotkb/Q9VZ47" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ47", "url": "https://www.uniprot.org/uniprotkb/Q9VZ47" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ47", "url": "https://www.uniprot.org/uniprotkb/Q9VZ47" } ], "pmid": "" }, { "name": "trans-Golgi network transport vesicle", "id": "GO:0030140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030140", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ47", "url": "https://www.uniprot.org/uniprotkb/Q9VZ47" } ], "pmid": "" } ], "biological_process": [ { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ47", "url": "https://www.uniprot.org/uniprotkb/Q9VZ47" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ47", "url": "https://www.uniprot.org/uniprotkb/Q9VZ47" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ47", "url": "https://www.uniprot.org/uniprotkb/Q9VZ47" } ], "pmid": "" }, { "name": "Rab protein signal transduction", "id": "GO:0032482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032482", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ47", "url": "https://www.uniprot.org/uniprotkb/Q9VZ47" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VZ47-1" }, { "uniprot_canonical_ac": "X2JB52-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JB52", "url": "https://www.uniprot.org/uniprotkb/X2JB52" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 459, "chemical_mass": 52589.0, "gene_names": "Dmel\\CG1637;CG1637;Dmel\\CG1637;Dmel_CG1637", "protein_name": "Purple acid phosphatase", "disease": [], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "X2JB52", "url": "https://www.uniprot.org/uniprotkb/X2JB52" } ], "pmid": "" }, { "name": "acid phosphatase activity", "id": "GO:0003993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003993", "evidence": [ { "database": "UniProtKB", "id": "X2JB52", "url": "https://www.uniprot.org/uniprotkb/X2JB52" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "X2JB52-1" }, { "uniprot_canonical_ac": "Q9VZ90-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZ90", "url": "https://www.uniprot.org/uniprotkb/Q9VZ90" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 117, "chemical_mass": 14254.0, "gene_names": "HL4;CG13712;Dmel\\CG13712;Dmel_CG13712;HL4", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VZ90-1" }, { "uniprot_canonical_ac": "Q9VZ99-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZ99", "url": "https://www.uniprot.org/uniprotkb/Q9VZ99" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 117, "chemical_mass": 13944.0, "gene_names": "HL1;CG13716;Dmel\\CG13716;Dmel_CG13716;HL1", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VZ99-1" }, { "uniprot_canonical_ac": "Q9VZL2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZL2", "url": "https://www.uniprot.org/uniprotkb/Q9VZL2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 777, "chemical_mass": 88771.0, "gene_names": "ida;APC5;Apc5;CG10850;Dmel\\CG10850;Dmel_CG10850;IDA;Ida;ida;l(3)63Fb;l(3)SH7", "protein_name": "Anaphase-promoting complex subunit 5", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VZL2", "url": "https://www.uniprot.org/uniprotkb/Q9VZL2" } ], "pmid": "" }, { "name": "anaphase-promoting complex", "id": "GO:0005680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005680", "evidence": [ { "database": "UniProtKB", "id": "Q9VZL2", "url": "https://www.uniprot.org/uniprotkb/Q9VZL2" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q9VZL2", "url": "https://www.uniprot.org/uniprotkb/Q9VZL2" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "Q9VZL2", "url": "https://www.uniprot.org/uniprotkb/Q9VZL2" } ], "pmid": "" }, { "name": "regulation of proteolysis", "id": "GO:0030162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030162", "evidence": [ { "database": "UniProtKB", "id": "Q9VZL2", "url": "https://www.uniprot.org/uniprotkb/Q9VZL2" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q9VZL2", "url": "https://www.uniprot.org/uniprotkb/Q9VZL2" } ], "pmid": "" }, { "name": "anaphase-promoting complex-dependent catabolic process", "id": "GO:0031145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031145", "evidence": [ { "database": "UniProtKB", "id": "Q9VZL2", "url": "https://www.uniprot.org/uniprotkb/Q9VZL2" } ], "pmid": "" }, { "name": "protein K11-linked ubiquitination", "id": "GO:0070979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070979", "evidence": [ { "database": "UniProtKB", "id": "Q9VZL2", "url": "https://www.uniprot.org/uniprotkb/Q9VZL2" } ], "pmid": "" }, { "name": "positive regulation of mitotic metaphase/anaphase transition", "id": "GO:0045842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045842", "evidence": [ { "database": "UniProtKB", "id": "Q9VZL2", "url": "https://www.uniprot.org/uniprotkb/Q9VZL2" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "Q9VZL2", "url": "https://www.uniprot.org/uniprotkb/Q9VZL2" } ], "pmid": "" }, { "name": "imaginal disc development", "id": "GO:0007444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007444", "evidence": [ { "database": "UniProtKB", "id": "Q9VZL2", "url": "https://www.uniprot.org/uniprotkb/Q9VZL2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VZL2-1" }, { "uniprot_canonical_ac": "Q9VZW7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZW7", "url": "https://www.uniprot.org/uniprotkb/Q9VZW7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 667, "chemical_mass": 75107.0, "gene_names": "CPT2;CG2107;CPT2;Cpt2;Dmel\\CG2107;Dmel_CG2107;SD01848p;cpt;dCPT2", "protein_name": "", "disease": [ { "disease_id": "DOID:0080000", "name": "muscular disease", "description": "A musculoskeletal system disease that affects the muscles.", "url": "https://disease-ontology.org/term/DOID:0080000", "evidence": [ { "id": "0080000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080000" } ], "weight": 0.0 }, { "disease_id": "DOID:3146", "name": "lipid metabolism disorder", "description": "An inherited metabolic disorder that involves the creation and degradation of lipids.", "url": "https://disease-ontology.org/term/DOID:3146", "evidence": [ { "id": "3146", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3146" } ], "weight": 0.0 }, { "disease_id": "DOID:936", "name": "brain disease", "description": "A central nervous system disease that is located_in the brain.", "url": "https://disease-ontology.org/term/DOID:936", "evidence": [ { "id": "936", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:936" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "carnitine O-palmitoyltransferase activity", "id": "GO:0004095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004095", "evidence": [ { "database": "UniProtKB", "id": "Q9VZW7", "url": "https://www.uniprot.org/uniprotkb/Q9VZW7" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VZW7", "url": "https://www.uniprot.org/uniprotkb/Q9VZW7" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid beta-oxidation", "id": "GO:0006635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006635", "evidence": [ { "database": "UniProtKB", "id": "Q9VZW7", "url": "https://www.uniprot.org/uniprotkb/Q9VZW7" } ], "pmid": "" }, { "name": "response to starvation", "id": "GO:0042594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042594", "evidence": [ { "database": "UniProtKB", "id": "Q9VZW7", "url": "https://www.uniprot.org/uniprotkb/Q9VZW7" } ], "pmid": "" }, { "name": "ketone body biosynthetic process", "id": "GO:0046951", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046951", "evidence": [ { "database": "UniProtKB", "id": "Q9VZW7", "url": "https://www.uniprot.org/uniprotkb/Q9VZW7" } ], "pmid": "" }, { "name": "triglyceride homeostasis", "id": "GO:0070328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070328", "evidence": [ { "database": "UniProtKB", "id": "Q9VZW7", "url": "https://www.uniprot.org/uniprotkb/Q9VZW7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VZW7-1" }, { "uniprot_canonical_ac": "Q9W030-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W030", "url": "https://www.uniprot.org/uniprotkb/Q9W030" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 313, "chemical_mass": 35245.0, "gene_names": "CG13805;CG13805;CG32302;Dmel\\CG32302;Dmel_CG32302", "protein_name": "Chitin-binding type-2 domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9W030", "url": "https://www.uniprot.org/uniprotkb/Q9W030" } ], "pmid": "" }, { "name": "external encapsulating structure", "id": "GO:0030312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030312", "evidence": [ { "database": "UniProtKB", "id": "Q9W030", "url": "https://www.uniprot.org/uniprotkb/Q9W030" } ], "pmid": "" } ], "molecular_function": [ { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "Q9W030", "url": "https://www.uniprot.org/uniprotkb/Q9W030" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W030-1" }, { "uniprot_canonical_ac": "Q9W039-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W039", "url": "https://www.uniprot.org/uniprotkb/Q9W039" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 375, "chemical_mass": 41974.0, "gene_names": "Dmel\\CG9018;CG9018;Dmel\\CG9018;Dmel_CG9018;FBgn0035318", "protein_name": "CID domain-containing protein", "disease": [], "molecular_function": [ { "name": "RNA polymerase II complex binding", "id": "GO:0000993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000993", "evidence": [ { "database": "UniProtKB", "id": "Q9W039", "url": "https://www.uniprot.org/uniprotkb/Q9W039" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "Q9W039", "url": "https://www.uniprot.org/uniprotkb/Q9W039" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W039-1" }, { "uniprot_canonical_ac": "Q9W048-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W048", "url": "https://www.uniprot.org/uniprotkb/Q9W048" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 342, "chemical_mass": 39264.0, "gene_names": "Dmel\\CG15879;CG15879;Dmel\\CG15879;Dmel_CG15879", "protein_name": "AB hydrolase-1 domain-containing protein", "disease": [], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q9W048", "url": "https://www.uniprot.org/uniprotkb/Q9W048" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W048-1" }, { "uniprot_canonical_ac": "Q9W0M0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W0M0", "url": "https://www.uniprot.org/uniprotkb/Q9W0M0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 262, "chemical_mass": 29204.0, "gene_names": "Dci;CG13890;DCI;Dci;Dmel\\CG13890;Dmel_CG13890;PEC1;PECI", "protein_name": "", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9W0M0", "url": "https://www.uniprot.org/uniprotkb/Q9W0M0" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "Q9W0M0", "url": "https://www.uniprot.org/uniprotkb/Q9W0M0" } ], "pmid": "" }, { "name": "peroxisomal matrix", "id": "GO:0005782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005782", "evidence": [ { "database": "UniProtKB", "id": "Q9W0M0", "url": "https://www.uniprot.org/uniprotkb/Q9W0M0" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid beta-oxidation", "id": "GO:0006635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006635", "evidence": [ { "database": "UniProtKB", "id": "Q9W0M0", "url": "https://www.uniprot.org/uniprotkb/Q9W0M0" } ], "pmid": "" }, { "name": "defense response to Gram-negative bacterium", "id": "GO:0050829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050829", "evidence": [ { "database": "UniProtKB", "id": "Q9W0M0", "url": "https://www.uniprot.org/uniprotkb/Q9W0M0" } ], "pmid": "" } ], "molecular_function": [ { "name": "delta(3)-delta(2)-enoyl-CoA isomerase activity", "id": "GO:0004165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004165", "evidence": [ { "database": "UniProtKB", "id": "Q9W0M0", "url": "https://www.uniprot.org/uniprotkb/Q9W0M0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W0M0-1" }, { "uniprot_canonical_ac": "Q9W0R2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W0R2", "url": "https://www.uniprot.org/uniprotkb/Q9W0R2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 345, "chemical_mass": 38732.0, "gene_names": "Dmel\\CG1231;CG1231;Dmel\\CG1231;Dmel_CG1231", "protein_name": "Matrin-type domain-containing protein", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R2", "url": "https://www.uniprot.org/uniprotkb/Q9W0R2" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R2", "url": "https://www.uniprot.org/uniprotkb/Q9W0R2" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R2", "url": "https://www.uniprot.org/uniprotkb/Q9W0R2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W0R2-1" }, { "uniprot_canonical_ac": "Q9W0Z7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W0Z7", "url": "https://www.uniprot.org/uniprotkb/Q9W0Z7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 249, "chemical_mass": 26825.0, "gene_names": "SP159;CG3650;Dmel\\CG3650;Dmel_CG3650;SP159", "protein_name": "trypsin", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "Q9W0Z7", "url": "https://www.uniprot.org/uniprotkb/Q9W0Z7" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9W0Z7", "url": "https://www.uniprot.org/uniprotkb/Q9W0Z7" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9W0Z7", "url": "https://www.uniprot.org/uniprotkb/Q9W0Z7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W0Z7-1" }, { "uniprot_canonical_ac": "Q9W101-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W101", "url": "https://www.uniprot.org/uniprotkb/Q9W101" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 172, "chemical_mass": 20760.0, "gene_names": "Dmel\\CG12849;CG12849;Dmel\\CG12849;Dmel_CG12849", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W101-1" }, { "uniprot_canonical_ac": "Q9W135-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W135", "url": "https://www.uniprot.org/uniprotkb/Q9W135" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 496, "chemical_mass": 56126.0, "gene_names": "CG13588;CG13588;CG3579;CG42360;Dmel\\CG42360;Dmel_CG42360", "protein_name": "RNase NYN domain-containing protein", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q9W135", "url": "https://www.uniprot.org/uniprotkb/Q9W135" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "Q9W135", "url": "https://www.uniprot.org/uniprotkb/Q9W135" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9W135", "url": "https://www.uniprot.org/uniprotkb/Q9W135" } ], "pmid": "" }, { "name": "cytoplasmic ribonucleoprotein granule", "id": "GO:0036464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036464", "evidence": [ { "database": "UniProtKB", "id": "Q9W135", "url": "https://www.uniprot.org/uniprotkb/Q9W135" } ], "pmid": "" } ], "biological_process": [ { "name": "3'-UTR-mediated mRNA destabilization", "id": "GO:0061158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061158", "evidence": [ { "database": "UniProtKB", "id": "Q9W135", "url": "https://www.uniprot.org/uniprotkb/Q9W135" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W135-1" }, { "uniprot_canonical_ac": "Q9W142-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W142", "url": "https://www.uniprot.org/uniprotkb/Q9W142" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 324, "chemical_mass": 35934.0, "gene_names": "Dmel\\CG13587;CG13587;Dmel\\CG13587;Dmel_CG13587", "protein_name": "C-type lectin domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W142-1" }, { "uniprot_canonical_ac": "Q9W155-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W155", "url": "https://www.uniprot.org/uniprotkb/Q9W155" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 572, "chemical_mass": 65589.0, "gene_names": "Ir60e;60e;CG13592;DmelIR60e;Dmel\\CG13592;Dmel_CG13592;IR60e;Ir60e", "protein_name": "", "disease": [], "biological_process": [ { "name": "detection of chemical stimulus", "id": "GO:0009593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009593", "evidence": [ { "database": "UniProtKB", "id": "Q9W155", "url": "https://www.uniprot.org/uniprotkb/Q9W155" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9W155", "url": "https://www.uniprot.org/uniprotkb/Q9W155" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9W155", "url": "https://www.uniprot.org/uniprotkb/Q9W155" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "Q9W155", "url": "https://www.uniprot.org/uniprotkb/Q9W155" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W155-1" }, { "uniprot_canonical_ac": "Q9W165-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W165", "url": "https://www.uniprot.org/uniprotkb/Q9W165" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 193, "chemical_mass": 22477.0, "gene_names": "Dmel\\CG13590;CG13590;Dmel\\CG13590;Dmel_CG13590", "protein_name": "MD-2-related lipid-recognition domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W165-1" }, { "uniprot_canonical_ac": "Q9W174-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W174", "url": "https://www.uniprot.org/uniprotkb/Q9W174" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 297, "chemical_mass": 33051.0, "gene_names": "Dmel\\CG15873;CG15873;Dmel\\CG15873;Dmel_CG15873;SP184;SPH184", "protein_name": "trypsin", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9W174", "url": "https://www.uniprot.org/uniprotkb/Q9W174" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9W174", "url": "https://www.uniprot.org/uniprotkb/Q9W174" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q9W174", "url": "https://www.uniprot.org/uniprotkb/Q9W174" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q9W174", "url": "https://www.uniprot.org/uniprotkb/Q9W174" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W174-1" }, { "uniprot_canonical_ac": "Q9W1F0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W1F0", "url": "https://www.uniprot.org/uniprotkb/Q9W1F0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 202, "chemical_mass": 22690.0, "gene_names": "Dmel\\CG13566;CG13566;Dmel\\CG13566;Dmel_CG13566", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W1F0-1" }, { "uniprot_canonical_ac": "Q9W1H6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W1H6", "url": "https://www.uniprot.org/uniprotkb/Q9W1H6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 260, "chemical_mass": 29649.0, "gene_names": "Dmel\\CG5597;5597;CG5597;CT17698;Dmel\\CG5597;Dmel_CG5597", "protein_name": "Ig-like domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W1H6-1" }, { "uniprot_canonical_ac": "Q9W1P1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W1P1", "url": "https://www.uniprot.org/uniprotkb/Q9W1P1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 195, "chemical_mass": 22245.0, "gene_names": "Dmel\\CG13558;CG13558;Dmel\\CG13558;Dmel_CG13558", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W1P1-1" }, { "uniprot_canonical_ac": "Q9W1R3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W1R3", "url": "https://www.uniprot.org/uniprotkb/Q9W1R3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1489, "chemical_mass": 170129.0, "gene_names": "Golgin245;CG3493;Dmel\\CG3493;Dmel_CG3493;Golgin245;dGolgin-245;dGolgin245;g245;golgin245", "protein_name": "", "disease": [], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q9W1R3", "url": "https://www.uniprot.org/uniprotkb/Q9W1R3" } ], "pmid": "" }, { "name": "trans-Golgi network membrane", "id": "GO:0032588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032588", "evidence": [ { "database": "UniProtKB", "id": "Q9W1R3", "url": "https://www.uniprot.org/uniprotkb/Q9W1R3" } ], "pmid": "" }, { "name": "Golgi trans cisterna", "id": "GO:0000138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000138", "evidence": [ { "database": "UniProtKB", "id": "Q9W1R3", "url": "https://www.uniprot.org/uniprotkb/Q9W1R3" } ], "pmid": "" } ], "molecular_function": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "Q9W1R3", "url": "https://www.uniprot.org/uniprotkb/Q9W1R3" } ], "pmid": "" } ], "biological_process": [ { "name": "Golgi vesicle transport", "id": "GO:0048193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048193", "evidence": [ { "database": "UniProtKB", "id": "Q9W1R3", "url": "https://www.uniprot.org/uniprotkb/Q9W1R3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W1R3-1" }, { "uniprot_canonical_ac": "Q9W1V0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W1V0", "url": "https://www.uniprot.org/uniprotkb/Q9W1V0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 367, "chemical_mass": 43137.0, "gene_names": "Gr59a;CG13537;CG30189;Dmel\\CG30189;Dmel_CG30189;GR59C.1;GR59a;Gr59a", "protein_name": "Gustatory receptor", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V0", "url": "https://www.uniprot.org/uniprotkb/Q9W1V0" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V0", "url": "https://www.uniprot.org/uniprotkb/Q9W1V0" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V0", "url": "https://www.uniprot.org/uniprotkb/Q9W1V0" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V0", "url": "https://www.uniprot.org/uniprotkb/Q9W1V0" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V0", "url": "https://www.uniprot.org/uniprotkb/Q9W1V0" } ], "pmid": "" }, { "name": "monoatomic ion transmembrane transport", "id": "GO:0034220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034220", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V0", "url": "https://www.uniprot.org/uniprotkb/Q9W1V0" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V0", "url": "https://www.uniprot.org/uniprotkb/Q9W1V0" } ], "pmid": "" }, { "name": "taste receptor activity", "id": "GO:0008527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008527", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V0", "url": "https://www.uniprot.org/uniprotkb/Q9W1V0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W1V0-1" }, { "uniprot_canonical_ac": "Q9W1W2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W1W2", "url": "https://www.uniprot.org/uniprotkb/Q9W1W2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 362, "chemical_mass": 37970.0, "gene_names": "CG9895;CG34209;CG42741;CG9895;Dmel\\CG42741;Dmel_CG42741", "protein_name": "C2H2-type domain-containing protein", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "Q9W1W2", "url": "https://www.uniprot.org/uniprotkb/Q9W1W2" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9W1W2", "url": "https://www.uniprot.org/uniprotkb/Q9W1W2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q9W1W2", "url": "https://www.uniprot.org/uniprotkb/Q9W1W2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9W1W2", "url": "https://www.uniprot.org/uniprotkb/Q9W1W2" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9W1W2", "url": "https://www.uniprot.org/uniprotkb/Q9W1W2" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "Q9W1W2", "url": "https://www.uniprot.org/uniprotkb/Q9W1W2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q9W1W2", "url": "https://www.uniprot.org/uniprotkb/Q9W1W2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q9W1W2", "url": "https://www.uniprot.org/uniprotkb/Q9W1W2" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "Q9W1W2", "url": "https://www.uniprot.org/uniprotkb/Q9W1W2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W1W2-1" }, { "uniprot_canonical_ac": "Q9W206-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W206", "url": "https://www.uniprot.org/uniprotkb/Q9W206" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1240, "chemical_mass": 144937.0, "gene_names": "CG13520;CG13520;CG30268;Dmel\\CG30268;Dmel_CG30268", "protein_name": "", "disease": [ { "disease_id": "DOID:0070311", "name": "oligoasthenoteratozoospermia", "description": "A form of male infertility that is characterized by a combination of low number or oligozoospermia, poor motility or asthenozoospermia, and abnormal shape or teratozoospermia of sperms. OAT is the most common cause of male subfertility.", "url": "https://disease-ontology.org/term/DOID:0070311", "evidence": [ { "id": "0070311", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070311" } ], "weight": 0.0 }, { "disease_id": "DOID:0070583", "name": "spermatogenic failure 84", "description": "A spermatogenic failure characterized by multiple morphologic abnormalities of the sperm flagella, resulting in severely reduced motility, that has_material_basis_in homozygous or compound heterozygous mutation in the CFAP61 gene on chromosome 20p11.23.", "url": "https://disease-ontology.org/term/DOID:0070583", "evidence": [ { "id": "0070583", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070583" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "Q9W206", "url": "https://www.uniprot.org/uniprotkb/Q9W206" } ], "pmid": "" } ], "biological_process": [ { "name": "sperm flagellum assembly", "id": "GO:0120316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120316", "evidence": [ { "database": "UniProtKB", "id": "Q9W206", "url": "https://www.uniprot.org/uniprotkb/Q9W206" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W206-1" }, { "uniprot_canonical_ac": "Q9W212-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W212", "url": "https://www.uniprot.org/uniprotkb/Q9W212" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 540, "chemical_mass": 63187.0, "gene_names": "CG13522;CG13522;CG13523;CG30259;Dmel\\CG30259;Dmel_CG30259", "protein_name": "Dynein regulatory complex subunit 2", "disease": [ { "disease_id": "DOID:0110611", "name": "primary ciliary dyskinesia 27", "description": "A primary ciliary dyskinesia that is characterized by autosomal recessive inheritance with neonatal respiratory distress, recurrent upper and lower airway disease, and bronchiectasis and has_material_basis_in homozygous mutation in the CCDC65 gene on chromosome 12q13.", "url": "https://disease-ontology.org/term/DOID:0110611", "evidence": [ { "id": "0110611", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110611" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "Q9W212", "url": "https://www.uniprot.org/uniprotkb/Q9W212" } ], "pmid": "" }, { "name": "axonemal dynein complex", "id": "GO:0005858", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005858", "evidence": [ { "database": "UniProtKB", "id": "Q9W212", "url": "https://www.uniprot.org/uniprotkb/Q9W212" } ], "pmid": "" } ], "biological_process": [ { "name": "cilium-dependent cell motility", "id": "GO:0060285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060285", "evidence": [ { "database": "UniProtKB", "id": "Q9W212", "url": "https://www.uniprot.org/uniprotkb/Q9W212" } ], "pmid": "" }, { "name": "axonemal dynein complex assembly", "id": "GO:0070286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070286", "evidence": [ { "database": "UniProtKB", "id": "Q9W212", "url": "https://www.uniprot.org/uniprotkb/Q9W212" } ], "pmid": "" }, { "name": "regulation of cilium movement", "id": "GO:0003352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003352", "evidence": [ { "database": "UniProtKB", "id": "Q9W212", "url": "https://www.uniprot.org/uniprotkb/Q9W212" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9W212-1", "start_pos": "500", "end_pos": "500", "site_lbl": "Thr500", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 500, "start_aa": "Thr", "end_pos": 500, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr500", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9W212-1" }, { "uniprot_canonical_ac": "Q9W246-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W246", "url": "https://www.uniprot.org/uniprotkb/Q9W246" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2733, "chemical_mass": 311904.0, "gene_names": "Dmel\\CG4554;CG4554;Dmel\\CG4554;Dmel_CG4554;GM01751p", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q9W246", "url": "https://www.uniprot.org/uniprotkb/Q9W246" } ], "pmid": "" }, { "name": "90S preribosome", "id": "GO:0030686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030686", "evidence": [ { "database": "UniProtKB", "id": "Q9W246", "url": "https://www.uniprot.org/uniprotkb/Q9W246" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "Q9W246", "url": "https://www.uniprot.org/uniprotkb/Q9W246" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9W246-1", "start_pos": "2516", "end_pos": "2516", "site_lbl": "Thr2516", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2516, "start_aa": "Thr", "end_pos": 2516, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2516", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9W246-1" }, { "uniprot_canonical_ac": "Q9W289-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W289", "url": "https://www.uniprot.org/uniprotkb/Q9W289" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 795, "chemical_mass": 90827.0, "gene_names": "GM130;CG11061;Dmel\\CG11061;Dmel_CG11061;GM-130;GM130;dGM130;dgm130", "protein_name": "", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q9W289", "url": "https://www.uniprot.org/uniprotkb/Q9W289" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q9W289", "url": "https://www.uniprot.org/uniprotkb/Q9W289" } ], "pmid": "" }, { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "Q9W289", "url": "https://www.uniprot.org/uniprotkb/Q9W289" } ], "pmid": "" }, { "name": "Golgi stack", "id": "GO:0005795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005795", "evidence": [ { "database": "UniProtKB", "id": "Q9W289", "url": "https://www.uniprot.org/uniprotkb/Q9W289" } ], "pmid": "" }, { "name": "cis-Golgi network", "id": "GO:0005801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005801", "evidence": [ { "database": "UniProtKB", "id": "Q9W289", "url": "https://www.uniprot.org/uniprotkb/Q9W289" } ], "pmid": "" }, { "name": "Golgi cis cisterna", "id": "GO:0000137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000137", "evidence": [ { "database": "UniProtKB", "id": "Q9W289", "url": "https://www.uniprot.org/uniprotkb/Q9W289" } ], "pmid": "" } ], "molecular_function": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "Q9W289", "url": "https://www.uniprot.org/uniprotkb/Q9W289" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of dendrite morphogenesis", "id": "GO:0050775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050775", "evidence": [ { "database": "UniProtKB", "id": "Q9W289", "url": "https://www.uniprot.org/uniprotkb/Q9W289" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "Q9W289", "url": "https://www.uniprot.org/uniprotkb/Q9W289" } ], "pmid": "" }, { "name": "Golgi vesicle transport", "id": "GO:0048193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048193", "evidence": [ { "database": "UniProtKB", "id": "Q9W289", "url": "https://www.uniprot.org/uniprotkb/Q9W289" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W289-1" }, { "uniprot_canonical_ac": "Q9W2C1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W2C1", "url": "https://www.uniprot.org/uniprotkb/Q9W2C1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 600, "chemical_mass": 68386.0, "gene_names": "comr;CG13493;Comr;Dmel\\CG13493;Dmel_CG13493;Z2-1340;comr;zab", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "Q9W2C1", "url": "https://www.uniprot.org/uniprotkb/Q9W2C1" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "Q9W2C1", "url": "https://www.uniprot.org/uniprotkb/Q9W2C1" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9W2C1", "url": "https://www.uniprot.org/uniprotkb/Q9W2C1" } ], "pmid": "" }, { "name": "euchromatin", "id": "GO:0000791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000791", "evidence": [ { "database": "UniProtKB", "id": "Q9W2C1", "url": "https://www.uniprot.org/uniprotkb/Q9W2C1" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "Q9W2C1", "url": "https://www.uniprot.org/uniprotkb/Q9W2C1" } ], "pmid": "" } ], "biological_process": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "Q9W2C1", "url": "https://www.uniprot.org/uniprotkb/Q9W2C1" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q9W2C1", "url": "https://www.uniprot.org/uniprotkb/Q9W2C1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W2C1-1" }, { "uniprot_canonical_ac": "Q9W2C5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W2C5", "url": "https://www.uniprot.org/uniprotkb/Q9W2C5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 199, "chemical_mass": 21278.0, "gene_names": "CT14230;BcDNA:LP06375;CG4363;CT14230;Dmel\\CG4363;Dmel_CG4363", "protein_name": "DUF753 domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W2C5-1" }, { "uniprot_canonical_ac": "Q9W2E3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W2E3", "url": "https://www.uniprot.org/uniprotkb/Q9W2E3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 341, "chemical_mass": 36253.0, "gene_names": "NC2alpha;CG10318;Dmel\\CG10318;Dmel_CG10318;Dr1-Drap1;Drap1;NC2-alpha;NC2alpha;NC2;Nc2alpha;dDrap1/dNC2a;dDrap1;dDrap;dNC2a;dNC2", "protein_name": "", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "Q9W2E3", "url": "https://www.uniprot.org/uniprotkb/Q9W2E3" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q9W2E3", "url": "https://www.uniprot.org/uniprotkb/Q9W2E3" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "Q9W2E3", "url": "https://www.uniprot.org/uniprotkb/Q9W2E3" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "Q9W2E3", "url": "https://www.uniprot.org/uniprotkb/Q9W2E3" } ], "pmid": "" }, { "name": "transcription by RNA polymerase II", "id": "GO:0006366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006366", "evidence": [ { "database": "UniProtKB", "id": "Q9W2E3", "url": "https://www.uniprot.org/uniprotkb/Q9W2E3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9W2E3", "url": "https://www.uniprot.org/uniprotkb/Q9W2E3" } ], "pmid": "" }, { "name": "negative cofactor 2 complex", "id": "GO:0017054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017054", "evidence": [ { "database": "UniProtKB", "id": "Q9W2E3", "url": "https://www.uniprot.org/uniprotkb/Q9W2E3" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "Q9W2E3", "url": "https://www.uniprot.org/uniprotkb/Q9W2E3" } ], "pmid": "" }, { "name": "core promoter sequence-specific DNA binding", "id": "GO:0001046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001046", "evidence": [ { "database": "UniProtKB", "id": "Q9W2E3", "url": "https://www.uniprot.org/uniprotkb/Q9W2E3" } ], "pmid": "" }, { "name": "RNA polymerase II general transcription initiation factor activity", "id": "GO:0016251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016251", "evidence": [ { "database": "UniProtKB", "id": "Q9W2E3", "url": "https://www.uniprot.org/uniprotkb/Q9W2E3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "Q9W2E3", "url": "https://www.uniprot.org/uniprotkb/Q9W2E3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9W2E3-1", "start_pos": "298", "end_pos": "298", "site_lbl": "Thr298", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 298, "start_aa": "Thr", "end_pos": 298, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr298", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9W2E3-1" }, { "uniprot_canonical_ac": "Q9W311-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W311", "url": "https://www.uniprot.org/uniprotkb/Q9W311" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 355, "chemical_mass": 40184.0, "gene_names": "Dmel\\CG15247;CG15247;Dmel\\CG15247;Dmel_CG15247", "protein_name": "CG15247-PA", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9W311-1", "start_pos": "113", "end_pos": "113", "site_lbl": "Thr113", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 113, "start_aa": "Thr", "end_pos": 113, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr113", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9W311-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Thr115", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 115, "start_aa": "Thr", "end_pos": 115, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr115", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9W311-1", "start_pos": "117", "end_pos": "117", "site_lbl": "Thr117", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 117, "start_aa": "Thr", "end_pos": 117, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr117", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9W311-1", "start_pos": "119", "end_pos": "119", "site_lbl": "Thr119", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 119, "start_aa": "Thr", "end_pos": 119, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr119", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9W311-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Thr124", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 124, "start_aa": "Thr", "end_pos": 124, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr124", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9W311-1", "start_pos": "179", "end_pos": "179", "site_lbl": "Thr179", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 179, "start_aa": "Thr", "end_pos": 179, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr179", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9W311-1" }, { "uniprot_canonical_ac": "Q9W3R2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W3R2", "url": "https://www.uniprot.org/uniprotkb/Q9W3R2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 177, "chemical_mass": 20075.0, "gene_names": "CheA7a;CG15033;CheA7a;Dmel\\CG15033;Dmel_CG15033", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R2", "url": "https://www.uniprot.org/uniprotkb/Q9W3R2" } ], "pmid": "" } ], "biological_process": [ { "name": "sensory perception of chemical stimulus", "id": "GO:0007606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007606", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R2", "url": "https://www.uniprot.org/uniprotkb/Q9W3R2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W3R2-1" }, { "uniprot_canonical_ac": "Q9W3Y8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W3Y8", "url": "https://www.uniprot.org/uniprotkb/Q9W3Y8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 266, "chemical_mass": 29760.0, "gene_names": "BcDNA:AT19932;BcDNA:AT19932;CG17717;Dmel\\CG17717;Dmel_CG17717", "protein_name": "RING-CH-type domain-containing protein", "disease": [], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9W3Y8", "url": "https://www.uniprot.org/uniprotkb/Q9W3Y8" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q9W3Y8", "url": "https://www.uniprot.org/uniprotkb/Q9W3Y8" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "Q9W3Y8", "url": "https://www.uniprot.org/uniprotkb/Q9W3Y8" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9W3Y8", "url": "https://www.uniprot.org/uniprotkb/Q9W3Y8" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q9W3Y8", "url": "https://www.uniprot.org/uniprotkb/Q9W3Y8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W3Y8-1" }, { "uniprot_canonical_ac": "Q9W471-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W471", "url": "https://www.uniprot.org/uniprotkb/Q9W471" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 145, "chemical_mass": 15461.0, "gene_names": "Cpr5C;CG4052;Cpr5C;Dmel\\CG4052;Dmel_CG4052", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "Q9W471", "url": "https://www.uniprot.org/uniprotkb/Q9W471" } ], "pmid": "" }, { "name": "chitin-based extracellular matrix", "id": "GO:0062129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062129", "evidence": [ { "database": "UniProtKB", "id": "Q9W471", "url": "https://www.uniprot.org/uniprotkb/Q9W471" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of chitin-based larval cuticle", "id": "GO:0008010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008010", "evidence": [ { "database": "UniProtKB", "id": "Q9W471", "url": "https://www.uniprot.org/uniprotkb/Q9W471" } ], "pmid": "" } ], "biological_process": [ { "name": "chitin-based cuticle development", "id": "GO:0040003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040003", "evidence": [ { "database": "UniProtKB", "id": "Q9W471", "url": "https://www.uniprot.org/uniprotkb/Q9W471" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W471-1" }, { "uniprot_canonical_ac": "Q9W4D3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W4D3", "url": "https://www.uniprot.org/uniprotkb/Q9W4D3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 513, "chemical_mass": 57711.0, "gene_names": "Dmel\\CG15930;CG15930;Dmel\\CG15930;Dmel_CG15930;Tdrd5l;tdrd5l", "protein_name": "Tudor domain-containing protein", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9W4D3", "url": "https://www.uniprot.org/uniprotkb/Q9W4D3" } ], "pmid": "" }, { "name": "cytoplasmic ribonucleoprotein granule", "id": "GO:0036464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036464", "evidence": [ { "database": "UniProtKB", "id": "Q9W4D3", "url": "https://www.uniprot.org/uniprotkb/Q9W4D3" } ], "pmid": "" } ], "biological_process": [ { "name": "male germ-line sex determination", "id": "GO:0019100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019100", "evidence": [ { "database": "UniProtKB", "id": "Q9W4D3", "url": "https://www.uniprot.org/uniprotkb/Q9W4D3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W4D3-1" }, { "uniprot_canonical_ac": "Q9W4N1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W4N1", "url": "https://www.uniprot.org/uniprotkb/Q9W4N1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 233, "chemical_mass": 27258.0, "gene_names": "mdcds_59461;CG15375;Dmel\\CG15375;Dmel_CG15375;mdcds_59461", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W4N1-1" }, { "uniprot_canonical_ac": "Q9W4P9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W4P9", "url": "https://www.uniprot.org/uniprotkb/Q9W4P9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 649, "chemical_mass": 75853.0, "gene_names": "Dmel\\CG2901;CG2901;Dmel\\CG2901;Dmel_CG2901", "protein_name": "Solute carrier family 53 member 1", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9W4P9", "url": "https://www.uniprot.org/uniprotkb/Q9W4P9" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphate transmembrane transporter activity", "id": "GO:0005315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005315", "evidence": [ { "database": "UniProtKB", "id": "Q9W4P9", "url": "https://www.uniprot.org/uniprotkb/Q9W4P9" } ], "pmid": "" }, { "name": "inositol hexakisphosphate binding", "id": "GO:0000822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000822", "evidence": [ { "database": "UniProtKB", "id": "Q9W4P9", "url": "https://www.uniprot.org/uniprotkb/Q9W4P9" } ], "pmid": "" } ], "biological_process": [ { "name": "phosphate ion transport", "id": "GO:0006817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006817", "evidence": [ { "database": "UniProtKB", "id": "Q9W4P9", "url": "https://www.uniprot.org/uniprotkb/Q9W4P9" } ], "pmid": "" }, { "name": "cellular response to phosphate starvation", "id": "GO:0016036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016036", "evidence": [ { "database": "UniProtKB", "id": "Q9W4P9", "url": "https://www.uniprot.org/uniprotkb/Q9W4P9" } ], "pmid": "" }, { "name": "synaptic target recognition", "id": "GO:0008039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008039", "evidence": [ { "database": "UniProtKB", "id": "Q9W4P9", "url": "https://www.uniprot.org/uniprotkb/Q9W4P9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W4P9-1" }, { "uniprot_canonical_ac": "Q9W4V0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W4V0", "url": "https://www.uniprot.org/uniprotkb/Q9W4V0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 826, "chemical_mass": 91897.0, "gene_names": "CG3591;CG18089;CG18852;CG32793;CG3591;Dmel\\CG32793;Dmel_CG32793;EG:100G7.1;EG:100G7.2;anon-3Ca;anon-3Cb", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W4V0-1" }, { "uniprot_canonical_ac": "X2JI50-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JI50", "url": "https://www.uniprot.org/uniprotkb/X2JI50" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1239, "chemical_mass": 133501.0, "gene_names": "Dmel\\CG2841;EG:BACH48C10.5;CG2841;Dmel\\CG2841;Dmel_CG2841;EG:BACH48C10.5;ptr", "protein_name": "WH2 domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "X2JI50-1", "start_pos": "1216", "end_pos": "1216", "site_lbl": "Thr1216", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1216, "start_aa": "Thr", "end_pos": 1216, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1216", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "X2JI50-1", "start_pos": "322", "end_pos": "322", "site_lbl": "Thr322", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 322, "start_aa": "Thr", "end_pos": 322, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr322", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "X2JI50-1", "start_pos": "359", "end_pos": "359", "site_lbl": "Thr359", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 359, "start_aa": "Thr", "end_pos": 359, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr359", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "X2JI50-1", "start_pos": "361", "end_pos": "361", "site_lbl": "Thr361", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 361, "start_aa": "Thr", "end_pos": 361, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr361", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "X2JI50-1", "start_pos": "518", "end_pos": "518", "site_lbl": "Thr518", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 518, "start_aa": "Thr", "end_pos": 518, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr518", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "X2JI50-1", "start_pos": "865", "end_pos": "865", "site_lbl": "Thr865", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 865, "start_aa": "Thr", "end_pos": 865, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr865", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "X2JI50-1" }, { "uniprot_canonical_ac": "Q9W5D7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W5D7", "url": "https://www.uniprot.org/uniprotkb/Q9W5D7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 478, "chemical_mass": 55213.0, "gene_names": "Dmel\\CG13361;CG13361;Dmel\\CG13361;Dmel_CG13361", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9W5D7-1" }, { "uniprot_canonical_ac": "Q9XZ12-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9XZ12", "url": "https://www.uniprot.org/uniprotkb/Q9XZ12" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 928, "chemical_mass": 103924.0, "gene_names": "Dmel\\CG7600;CG7600;Dmel\\CG7600;Dmel_CG7600", "protein_name": "Protein FAM91A1", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9XZ12-1" }, { "uniprot_canonical_ac": "V9H0I1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "V9H0I1", "url": "https://www.uniprot.org/uniprotkb/V9H0I1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 440, "chemical_mass": 51705.0, "gene_names": "mthl13;CG30018;Dmel\\CG30018;Dmel_CG30018;Mthl13;mthl13", "protein_name": "", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "V9H0I1", "url": "https://www.uniprot.org/uniprotkb/V9H0I1" } ], "pmid": "" }, { "name": "G protein-coupled peptide receptor activity", "id": "GO:0008528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008528", "evidence": [ { "database": "UniProtKB", "id": "V9H0I1", "url": "https://www.uniprot.org/uniprotkb/V9H0I1" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "V9H0I1", "url": "https://www.uniprot.org/uniprotkb/V9H0I1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "V9H0I1", "url": "https://www.uniprot.org/uniprotkb/V9H0I1" } ], "pmid": "" } ], "biological_process": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "V9H0I1", "url": "https://www.uniprot.org/uniprotkb/V9H0I1" } ], "pmid": "" }, { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "V9H0I1", "url": "https://www.uniprot.org/uniprotkb/V9H0I1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "V9H0I1-1" }, { "uniprot_canonical_ac": "X2J4U0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2J4U0", "url": "https://www.uniprot.org/uniprotkb/X2J4U0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 141, "chemical_mass": 16408.0, "gene_names": "Dmel\\CG44574;CG44574;Dmel\\CG44574;Dmel_CG44574", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "X2J4U0-1" }, { "uniprot_canonical_ac": "X2J8Q7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2J8Q7", "url": "https://www.uniprot.org/uniprotkb/X2J8Q7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 92, "chemical_mass": 10356.0, "gene_names": "Dmel\\CG44521;CG44521;Dmel\\CG44521;Dmel_CG44521;FBgn0265714", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "X2J8Q7-1" }, { "uniprot_canonical_ac": "X2J8S3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2J8S3", "url": "https://www.uniprot.org/uniprotkb/X2J8S3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 94, "chemical_mass": 10698.0, "gene_names": "Dmel\\CG44406;CG44406;Dmel\\CG44406;Dmel_CG44406", "protein_name": "Kazal-like domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "X2J8S3-1" }, { "uniprot_canonical_ac": "X2J9G7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2J9G7", "url": "https://www.uniprot.org/uniprotkb/X2J9G7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 35, "chemical_mass": 4063.0, "gene_names": "chr2L_11663230_11663806;CG44477;Dmel\\CG44477;Dmel_CG44477;FBgn0265670;chr2L_11663230_11663806", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "X2J9G7-1" }, { "uniprot_canonical_ac": "X2JA25-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JA25", "url": "https://www.uniprot.org/uniprotkb/X2JA25" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 45, "chemical_mass": 5052.0, "gene_names": "Dmel\\CG45690;CG45690;Dmel\\CG45690;Dmel_CG45690;FBgn0267254", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "X2JA25-1" }, { "uniprot_canonical_ac": "X2JB67-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JB67", "url": "https://www.uniprot.org/uniprotkb/X2JB67" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 72, "chemical_mass": 7957.0, "gene_names": "Dmel\\CG34250;CG34250;Dmel\\CG34250;Dmel_CG34250", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "X2JB67-1" }, { "uniprot_canonical_ac": "X2JBD0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JBD0", "url": "https://www.uniprot.org/uniprotkb/X2JBD0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1552, "chemical_mass": 142914.0, "gene_names": "Muc11A;CG2779;CG32656;Dmel\\CG32656;Dmel_CG32656;Muc11A", "protein_name": "", "disease": [ { "disease_id": "DOID:0050156", "name": "idiopathic pulmonary fibrosis", "description": "A pulmonary fibrosis that is characterized by scarring of the lung characterized by stiffness in the lungs and makes it difficult to breathe.", "url": "https://disease-ontology.org/term/DOID:0050156", "evidence": [ { "id": "0050156", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050156" } ], "weight": 0.0 }, { "disease_id": "DOID:0050625", "name": "biliary tract benign neoplasm", "description": "A hepatobiliary benign neoplasm located_in the biliary tract.", "url": "https://disease-ontology.org/term/DOID:0050625", "evidence": [ { "id": "0050625", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050625" } ], "weight": 0.0 }, { "disease_id": "DOID:0050848", "name": "obstructive sleep apnea", "description": "A sleep apnea that is characterized by repeated collapse and obstruction of the upper airway during sleep, which results in reduced airflow (hypopnea) or complete airflow cessation (apnea), oxygen desaturation, and arousals from sleep.", "url": "https://disease-ontology.org/term/DOID:0050848", "evidence": [ { "id": "0050848", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050848" } ], "weight": 0.0 }, { "disease_id": "DOID:0061118", "name": "autosomal dominant tubulointerstitial kidney disease 2", "description": "An autosomal dominant tubulointerstitial kidney disease characterized by adult onset of impaired renal function and salt wasting resulting in chronic renal insufficiency and end-stage renal failure by the sixth decade that has_material_basis_in eterozygous mutation in the MUC1 gene on chromosome 1q22.", "url": "https://disease-ontology.org/term/DOID:0061118", "evidence": [ { "id": "0061118", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061118" } ], "weight": 0.0 }, { "disease_id": "DOID:10140", "name": "dry eye syndrome", "description": "A lacrimal apparatus disease that is characterized by persistent irritation or burning of the coreneal surface.", "url": "https://disease-ontology.org/term/DOID:10140", "evidence": [ { "id": "10140", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10140" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:11204", "name": "allergic conjunctivitis", "description": "A chronic conjunctivitis that is an inflammation of the conjunctiva involing red, itchy, and watery eyes a resulting from an exposure to an allergen or an irritant.", "url": "https://disease-ontology.org/term/DOID:11204", "evidence": [ { "id": "11204", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11204" } ], "weight": 0.0 }, { "disease_id": "DOID:11339", "name": "pneumocystosis", "description": "An opportunistic mycosis that is located in lungs, but can also occur in eyes, ears, skin, thyroid, pituitary, palate, parathyroid, esophagus, pleura, heart, liver, spleen, small intestine, adrenals, kidneys, bone marrow, and lymph nodes, has_material_basis_in Pneumocystis jirovecii that effects interstitial and alveolar tissues and has symptom nonproductive cough, has symptom shortness of breath, and has symptom fever.", "url": "https://disease-ontology.org/term/DOID:11339", "evidence": [ { "id": "11339", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11339" } ], "weight": 0.0 }, { "disease_id": "DOID:11394", "name": "adult respiratory distress syndrome", "description": "A respiratory failure that results from diffuse injury to the endothelium of the lung (as in sepsis, chest trauma, massive blood transfusion, aspiration of the gastric contents, or pneumonia) and is characterized by pulmonary edema with an abnormally high amount of protein in the edematous fluid and by difficult rapid breathing and hypoxemia.", "url": "https://disease-ontology.org/term/DOID:11394", "evidence": [ { "id": "11394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11394" } ], "weight": 0.0 }, { "disease_id": "DOID:114", "name": "heart disease", "description": "A cardiovascular system disease that involves the heart.", "url": "https://disease-ontology.org/term/DOID:114", "evidence": [ { "id": "114", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:114" } ], "weight": 0.0 }, { "disease_id": "DOID:11650", "name": "bronchopulmonary dysplasia", "description": "A lung disease that is characterized by underdeveloped lungs in newborns that can be easily irritated or inflamed after birth resulting in damage to the alveoli of the lungs and bronchi. Most newborns who develop BPD are born more than 10 weeks before their due dates, weigh less than 2 pounds at birth, and have breathing problems.", "url": "https://disease-ontology.org/term/DOID:11650", "evidence": [ { "id": "11650", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11650" } ], "weight": 0.0 }, { "disease_id": "DOID:13406", "name": "pulmonary sarcoidosis", "description": "A sarcoidosis that is characterized by noncaseating granulomatous infiltration of the lungs and supporting lymph nodes, bilateral hilar adenopathy, and pulmonary issues, has_symptom shortness of breath, fatigue, wheezing, and chronic cough, and develops_from a type IV hypersensitivity reaction.", "url": "https://disease-ontology.org/term/DOID:13406", "evidence": [ { "id": "13406", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13406" } ], "weight": 0.0 }, { "disease_id": "DOID:13891", "name": "bird fancier's lung", "description": "An extrinsic allergic alveolitis which is caused by inhalation of antigens from avian excreta. The disease has_symptom abrupt onset of dyspnea, has_symptom cough, has_symptom malaise, and has_symptom fever, after exposure to antigen.", "url": "https://disease-ontology.org/term/DOID:13891", "evidence": [ { "id": "13891", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13891" } ], "weight": 0.0 }, { "disease_id": "DOID:1485", "name": "cystic fibrosis", "description": "A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs.", "url": "https://disease-ontology.org/term/DOID:1485", "evidence": [ { "id": "1485", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1485" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:2799", "name": "bronchiolitis obliterans", "description": "A obstructive lung disease involving obstruction of the bronchioles due to inflammation and fibrosis which occurs as a complication of various lung conditions or physiological insults.", "url": "https://disease-ontology.org/term/DOID:2799", "evidence": [ { "id": "2799", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2799" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:3030", "name": "mucinous adenocarcinoma", "description": "An adenocarcinoma that derives_from epithelial cells originating in glandular tissue, which produce mucin.", "url": "https://disease-ontology.org/term/DOID:3030", "evidence": [ { "id": "3030", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3030" } ], "weight": 0.0 }, { "disease_id": "DOID:3082", "name": "interstitial lung disease", "description": "A lung disease that is characterized by inflammation and altered lung interstitium compromising pulmonary function and often has_symptom shortness of breath, dyspnea, and/or cough.", "url": "https://disease-ontology.org/term/DOID:3082", "evidence": [ { "id": "3082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3082" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:3458", "name": "breast adenocarcinoma", "description": "A breast carcinoma that originates in the milk ducts and/or lobules (glandular tissue) of the breast.", "url": "https://disease-ontology.org/term/DOID:3458", "evidence": [ { "id": "3458", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3458" } ], "weight": 0.0 }, { "disease_id": "DOID:3587", "name": "pancreatic ductal carcinoma", "description": "A pancreatic carcinoma located_in the pancreatic duct.", "url": "https://disease-ontology.org/term/DOID:3587", "evidence": [ { "id": "3587", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3587" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:418", "name": "systemic scleroderma", "description": "A scleroderma that is characterized by fibrosis (or hardening) of the skin and major organs, as well as vascular alterations, and autoantibodies.", "url": "https://disease-ontology.org/term/DOID:418", "evidence": [ { "id": "418", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:418" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:4481", "name": "allergic rhinitis", "description": "A rhinitis that is an allergic inflammation and irritation of the nasal airways involving sneezing, runny nose, nasal congestion, itching and tearing of the eyes caused by exposure to an allergen such as pollen, dust, mold, animal dander and droppings of cockroaches or house dust mites.", "url": "https://disease-ontology.org/term/DOID:4481", "evidence": [ { "id": "4481", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4481" } ], "weight": 0.0 }, { "disease_id": "DOID:4608", "name": "common bile duct neoplasm", "description": "", "url": "https://disease-ontology.org/term/DOID:4608", "evidence": [ { "id": "4608", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4608" } ], "weight": 0.0 }, { "disease_id": "DOID:4947", "name": "cholangiocarcinoma", "description": "A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4947", "evidence": [ { "id": "4947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4947" } ], "weight": 0.0 }, { "disease_id": "DOID:552", "name": "pneumonia", "description": "A lung disease that involves lung parenchyma or alveolar inflammation and abnormal alveolar filling with fluid (consolidation and exudation). It results from a variety of causes including infection with bacteria, viruses, fungi or parasites, and chemical or physical injury to the lungs. It is accompanied by fever, chills, cough, and difficulty in breathing.", "url": "https://disease-ontology.org/term/DOID:552", "evidence": [ { "id": "552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:552" } ], "weight": 0.0 }, { "disease_id": "DOID:850", "name": "lung disease", "description": "A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide.", "url": "https://disease-ontology.org/term/DOID:850", "evidence": [ { "id": "850", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:850" } ], "weight": 0.0 }, { "disease_id": "DOID:8622", "name": "measles", "description": "A viral infectious disease that results_in infection located_in skin, has_material_basis_in Measles virus (Morbillivirus hominis), which is transmitted_by contact with oronasal secretions, or semen of an infected person. The infection has_symptom fever, has_symptom cough, has_symptom coryza, has_symptom conjunctivitis, and has_symptom maculopapular, erythematous rash.", "url": "https://disease-ontology.org/term/DOID:8622", "evidence": [ { "id": "8622", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8622" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "X2JBD0", "url": "https://www.uniprot.org/uniprotkb/X2JBD0" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "X2JBD0", "url": "https://www.uniprot.org/uniprotkb/X2JBD0" } ], "pmid": "" } ], "molecular_function": [ { "name": "extracellular matrix structural constituent", "id": "GO:0005201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005201", "evidence": [ { "database": "UniProtKB", "id": "X2JBD0", "url": "https://www.uniprot.org/uniprotkb/X2JBD0" } ], "pmid": "" }, { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "X2JBD0", "url": "https://www.uniprot.org/uniprotkb/X2JBD0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "X2JBD0-1", "start_pos": "292", "end_pos": "292", "site_lbl": "Thr292", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 292, "start_aa": "Thr", "end_pos": 292, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr292", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "X2JBD0-1", "start_pos": "86", "end_pos": "86", "site_lbl": "Thr86", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 86, "start_aa": "Thr", "end_pos": 86, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr86", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "X2JBD0-1" }, { "uniprot_canonical_ac": "X2JBL3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JBL3", "url": "https://www.uniprot.org/uniprotkb/X2JBL3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 187, "chemical_mass": 20848.0, "gene_names": "Dmel\\CG44437;CG1903;CG44437;Dmel\\CG44437;Dmel_CG44437", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "X2JBL3-1" }, { "uniprot_canonical_ac": "X2JCU8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JCU8", "url": "https://www.uniprot.org/uniprotkb/X2JCU8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 964, "chemical_mass": 104576.0, "gene_names": "CG14126;CG5917;CG14126;CG14129;CG34420;CG44837;CG5917;Dmel\\CG44837;Dmel_CG44837", "protein_name": "Dipeptidase", "disease": [], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "X2JCU8", "url": "https://www.uniprot.org/uniprotkb/X2JCU8" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "X2JCU8", "url": "https://www.uniprot.org/uniprotkb/X2JCU8" } ], "pmid": "" }, { "name": "metallodipeptidase activity", "id": "GO:0070573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070573", "evidence": [ { "database": "UniProtKB", "id": "X2JCU8", "url": "https://www.uniprot.org/uniprotkb/X2JCU8" } ], "pmid": "" }, { "name": "dipeptidase activity", "id": "GO:0016805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016805", "evidence": [ { "database": "UniProtKB", "id": "X2JCU8", "url": "https://www.uniprot.org/uniprotkb/X2JCU8" } ], "pmid": "" } ], "cellular_component": [ { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "X2JCU8", "url": "https://www.uniprot.org/uniprotkb/X2JCU8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "X2JCU8-1", "start_pos": "265", "end_pos": "265", "site_lbl": "Thr265", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 265, "start_aa": "Thr", "end_pos": 265, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr265", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "X2JCU8-1", "start_pos": "267", "end_pos": "267", "site_lbl": "Thr267", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 267, "start_aa": "Thr", "end_pos": 267, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr267", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "X2JCU8-1", "start_pos": "357", "end_pos": "357", "site_lbl": "Thr357", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 357, "start_aa": "Thr", "end_pos": 357, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr357", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "X2JCU8-1" }, { "uniprot_canonical_ac": "X2JFV5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JFV5", "url": "https://www.uniprot.org/uniprotkb/X2JFV5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 90, "chemical_mass": 9969.0, "gene_names": "Dmel\\CG45487;CG45487;Dmel\\CG45487;Dmel_CG45487", "protein_name": "DUF4777 domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "X2JFV5-1" }, { "uniprot_canonical_ac": "X2JK14-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JK14", "url": "https://www.uniprot.org/uniprotkb/X2JK14" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 95, "chemical_mass": 10672.0, "gene_names": "Dmel\\CG44428;CG44428;Dmel\\CG44428;Dmel_CG44428;FBgn0265610", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "X2JK14-1" }, { "uniprot_canonical_ac": "A0A0B4JCY7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4JCY7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4JCY7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 107, "chemical_mass": 12309.0, "gene_names": "pre-mod(mdg4)-AD;CG42773;Dmel\\CG42773;Dmel_CG42773;RAD;pre-mod(mdg4)-AD", "protein_name": "", "disease": [], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4JCY7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4JCY7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4JCY7-1" }, { "uniprot_canonical_ac": "A0A0B4JDD0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4JDD0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4JDD0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1264, "chemical_mass": 143417.0, "gene_names": "Pif1A;BcDNA:GH12504;CG11773;CG11774;CG11776;CG32940;CG33719;CG42599;CG9808;DM22;Dmel\\CG42599;Dmel_CG42599;IP06413p;PIF-1A;Pif1A;Pif1", "protein_name": "", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4JDD0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4JDD0" } ], "pmid": "" }, { "name": "investment cone", "id": "GO:0070865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070865", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4JDD0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4JDD0" } ], "pmid": "" } ], "biological_process": [ { "name": "sperm individualization", "id": "GO:0007291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007291", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4JDD0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4JDD0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4JDD0-1", "start_pos": "697", "end_pos": "697", "site_lbl": "Thr697", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 697, "start_aa": "Thr", "end_pos": 697, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr697", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A0A0B4JDD0-1" }, { "uniprot_canonical_ac": "A0A0B4JDD7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4JDD7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4JDD7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 138, "chemical_mass": 15908.0, "gene_names": "Dmel\\CG42857;CG42857;DMG6-MB6.chr3R.10.010;Dmel\\CG42857;Dmel_CG42857", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4JDD7-1" }, { "uniprot_canonical_ac": "A0A0B4JDE5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4JDE5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4JDE5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 94, "chemical_mass": 10882.0, "gene_names": "Dmel\\CG42870;CG42870;Dmel\\CG42870;Dmel_CG42870;lincRNA.828", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4JDE5-1" }, { "uniprot_canonical_ac": "A0A0B4K5Z8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K5Z8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 781, "chemical_mass": 87568.0, "gene_names": "Sec23;CG1250;COPII;Dmel\\CG1250;Dmel_CG1250;Hau;SEC23;Sec23A;Sec23p;Sec23;dSec23p;dSec23;dar2;dsec23p;dsec23;hau;sec23", "protein_name": "Protein transport protein SEC23", "disease": [ { "disease_id": "DOID:0070307", "name": "craniolenticulosutural dysplasia", "description": "A syndrome in neonates that is characterized by facial dysmorphism, late-closing fontanels, cataract, and skeletal defects. It has_material_basis_in the mutation of the SEC23A gene on the 14th chromosome, with the underproduction in the collagen secreting pathway and distension of endoplasmic reticulum leading to bone defects.", "url": "https://disease-ontology.org/term/DOID:0070307", "evidence": [ { "id": "0070307", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070307" } ], "weight": 0.0 }, { "disease_id": "DOID:0081003", "name": "Cowden syndrome 7", "description": "A Cowden syndrome that has_material_basis_in heterozygous mutation in the SEC23B gene on chromosome 20p11.", "url": "https://disease-ontology.org/term/DOID:0081003", "evidence": [ { "id": "0081003", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081003" } ], "weight": 0.0 }, { "disease_id": "DOID:0111401", "name": "congenital dyserythropoietic anemia type II", "description": "A congenital dyserythropoietic anemia characterized by mild to severe anemia, bi- and multinucleated erythroblasts in bone marrow, jaundice and splenomegaly and may lead to liver iron overload and gallstones that has_material_basis_in homozygous or compound heterozygous mutation in the SEC23B gene on chromosome 20p11.23.", "url": "https://disease-ontology.org/term/DOID:0111401", "evidence": [ { "id": "0111401", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111401" } ], "weight": 0.0 }, { "disease_id": "DOID:5325", "name": "Roberts syndrome", "description": "A syndrome characterized by tetraphocomelia, craniofacial anomalies, growth retardation, intellectual disability, and cardiac and renal abnormalities that has_material_basis_in homozygous or compound heterozygous mutation in the ESCO2 gene on chromosome 8p21.1.", "url": "https://disease-ontology.org/term/DOID:5325", "evidence": [ { "id": "5325", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5325" } ], "weight": 0.0 } ], "biological_process": [ { "name": "COPII-coated vesicle cargo loading", "id": "GO:0090110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090110", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K5Z8" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K5Z8" } ], "pmid": "" }, { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K5Z8" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K5Z8" } ], "pmid": "" }, { "name": "positive regulation of dendrite morphogenesis", "id": "GO:0050775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050775", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K5Z8" } ], "pmid": "" }, { "name": "protein secretion", "id": "GO:0009306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009306", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K5Z8" } ], "pmid": "" }, { "name": "protein localization to cell surface", "id": "GO:0034394", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034394", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K5Z8" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K5Z8" } ], "pmid": "" }, { "name": "positive regulation of ER to Golgi vesicle-mediated transport", "id": "GO:1902953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902953", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K5Z8" } ], "pmid": "" }, { "name": "positive regulation of protein exit from endoplasmic reticulum", "id": "GO:0070863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070863", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K5Z8" } ], "pmid": "" }, { "name": "extracellular matrix constituent secretion", "id": "GO:0070278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070278", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K5Z8" } ], "pmid": "" }, { "name": "regulation of COPII vesicle coating", "id": "GO:0003400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003400", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K5Z8" } ], "pmid": "" }, { "name": "larval chitin-based cuticle development", "id": "GO:0008363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008363", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K5Z8" } ], "pmid": "" }, { "name": "lumen formation, open tracheal system", "id": "GO:0035149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035149", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K5Z8" } ], "pmid": "" }, { "name": "chitin-based larval cuticle pattern formation", "id": "GO:0035293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035293", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K5Z8" } ], "pmid": "" }, { "name": "chitin-based cuticle development", "id": "GO:0040003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040003", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K5Z8" } ], "pmid": "" }, { "name": "COPII-coated vesicle budding", "id": "GO:0090114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090114", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K5Z8" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K5Z8" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K5Z8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K5Z8" } ], "pmid": "" }, { "name": "COPII-coated ER to Golgi transport vesicle", "id": "GO:0030134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030134", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K5Z8" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K5Z8" } ], "pmid": "" }, { "name": "endoplasmic reticulum exit site", "id": "GO:0070971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070971", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K5Z8" } ], "pmid": "" }, { "name": "Golgi stack", "id": "GO:0005795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005795", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K5Z8" } ], "pmid": "" }, { "name": "COPII vesicle coat", "id": "GO:0030127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030127", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K5Z8" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K5Z8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K5Z8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4K5Z8-1" }, { "uniprot_canonical_ac": "A0A0B4K691-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K691", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K691" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 568, "chemical_mass": 65443.0, "gene_names": "rpk;CG1058;Dmel\\CG1058;Dmel_CG1058;GNaC1;RPK;Rpk;dGNaC1;ppk2;rpk", "protein_name": "", "disease": [ { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:14452", "name": "hypokalemic periodic paralysis", "description": "", "url": "https://disease-ontology.org/term/DOID:14452", "evidence": [ { "id": "14452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14452" } ], "weight": 0.0 }, { "disease_id": "DOID:326", "name": "ischemia", "description": "A vascular disease that is characterized by a restriction in blood supply to tissues.", "url": "https://disease-ontology.org/term/DOID:326", "evidence": [ { "id": "326", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:326" } ], "weight": 0.0 } ], "biological_process": [ { "name": "sensory perception of touch", "id": "GO:0050975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050975", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K691", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K691" } ], "pmid": "" }, { "name": "detection of mechanical stimulus involved in sensory perception of pain", "id": "GO:0050966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050966", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K691", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K691" } ], "pmid": "" }, { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K691", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K691" } ], "pmid": "" }, { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K691", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K691" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K691", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K691" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K691", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K691" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K691", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K691" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K691", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K691" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K691", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K691" } ], "pmid": "" } ], "molecular_function": [ { "name": "sodium channel activity", "id": "GO:0005272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005272", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K691", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K691" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4K691-1" }, { "uniprot_canonical_ac": "A0A0B4K6S3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6S3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6S3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 121, "chemical_mass": 13287.0, "gene_names": "Dmel\\CG43131;CG43131;Dmel\\CG43131;Dmel_CG43131", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4K6S3-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Thr21", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 21, "start_aa": "Thr", "end_pos": 21, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr21", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A0A0B4K6S3-1" }, { "uniprot_canonical_ac": "A0A0B4K774-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 477, "chemical_mass": 52407.0, "gene_names": "Abi;Abi-1;Abi;Ablphilin;CG9749;Dmel\\CG9749;Dmel_CG9749;abi;dAbi", "protein_name": "", "disease": [], "cellular_component": [ { "name": "basal cortex", "id": "GO:0045180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045180", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "basal part of cell", "id": "GO:0045178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045178", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "SCAR complex", "id": "GO:0031209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031209", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "lamellipodium membrane", "id": "GO:0031258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031258", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "actin-based cell projection", "id": "GO:0098858", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098858", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of cytoskeleton organization", "id": "GO:0051495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051495", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "establishment of planar polarity of follicular epithelium", "id": "GO:0042247", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042247", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "neuromuscular junction development", "id": "GO:0007528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007528", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "positive regulation of G2/M transition of mitotic cell cycle", "id": "GO:0010971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010971", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "neuron migration", "id": "GO:0001764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001764", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "cell adhesion mediated by integrin", "id": "GO:0033627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033627", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "positive regulation of stress fiber assembly", "id": "GO:0051496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051496", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "lamellipodium assembly", "id": "GO:0030032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030032", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton organization", "id": "GO:0030866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030866", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "positive regulation of filopodium assembly", "id": "GO:0051491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051491", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "central nervous system neuron axonogenesis", "id": "GO:0021955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021955", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "axon extension involved in axon guidance", "id": "GO:0048846", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048846", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "cell projection morphogenesis", "id": "GO:0048858", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048858", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "cell projection assembly", "id": "GO:0030031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030031", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "chaeta development", "id": "GO:0022416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022416", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "centripetally migrating follicle cell migration", "id": "GO:0060269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060269", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "photoreceptor cell axon guidance", "id": "GO:0072499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072499", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "somatic muscle attachment to chitin-based cuticle", "id": "GO:0160175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160175", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "regulation of Arp2/3 complex-mediated actin nucleation", "id": "GO:0034315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034315", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" } ], "molecular_function": [ { "name": "cadherin binding", "id": "GO:0045296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045296", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "signaling adaptor activity", "id": "GO:0035591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035591", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K774", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K774" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4K774-1", "start_pos": "203", "end_pos": "203", "site_lbl": "Thr203", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 203, "start_aa": "Thr", "end_pos": 203, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr203", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K774-1", "start_pos": "262", "end_pos": "262", "site_lbl": "Thr262", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 262, "start_aa": "Thr", "end_pos": 262, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr262", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A0A0B4K774", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A0B4K774" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K774-1", "start_pos": "269", "end_pos": "269", "site_lbl": "Thr269", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 269, "start_aa": "Thr", "end_pos": 269, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr269", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A0A0B4K774", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A0B4K774" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K774-1", "start_pos": "270", "end_pos": "270", "site_lbl": "Thr270", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 270, "start_aa": "Thr", "end_pos": 270, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr270", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A0A0B4K774", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A0B4K774" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K774-1", "start_pos": "271", "end_pos": "271", "site_lbl": "Thr271", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 271, "start_aa": "Thr", "end_pos": 271, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr271", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A0A0B4K774", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A0B4K774" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K774-1", "start_pos": "272", "end_pos": "272", "site_lbl": "Thr272", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 272, "start_aa": "Thr", "end_pos": 272, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr272", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A0A0B4K774", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A0B4K774" } ] } ] } ], "record_id": "A0A0B4K774-1" }, { "uniprot_canonical_ac": "A0A0B4K7A7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7A7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7A7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 258, "chemical_mass": 29269.0, "gene_names": "Dmel\\CG43125;CG43125;Dmel\\CG43125;Dmel_CG43125;SPH250", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7A7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7A7" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7A7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7A7" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7A7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7A7" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7A7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7A7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4K7A7-1" }, { "uniprot_canonical_ac": "A0A0B4K7H3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7H3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7H3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 112, "chemical_mass": 12862.0, "gene_names": "euc;CG12269;Dmel\\CG12269;Dmel_CG12269;euc", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7H3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7H3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4K7H3-1" }, { "uniprot_canonical_ac": "A0A0B4K7K5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 127, "chemical_mass": 14255.0, "gene_names": "Dmel\\CG43393;CG43393;Dmel\\CG43393;Dmel_CG43393", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4K7K5-1" }, { "uniprot_canonical_ac": "A0A0B4K7P2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7P2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7P2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 170, "chemical_mass": 19303.0, "gene_names": "noncoding_6564;CG43192;Dmel\\CG43192;Dmel_CG43192;noncoding_6564;noncoding_6907", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4K7P2-1" }, { "uniprot_canonical_ac": "A0A0B4K7T3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7T3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7T3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 250, "chemical_mass": 28234.0, "gene_names": "AAF57948;AAL48972;AAF57948;AAL48972;CG5550;Dmel\\CG5550;Dmel_CG5550;FBpp0086184", "protein_name": "Fibrinogen C-terminal domain-containing protein", "disease": [ { "disease_id": "DOID:0060768", "name": "Smith-Magenis syndrome", "description": "A chromosomal deletion syndrome that is characterized by mild-to-moderate infantile hypotonia, minor skeletal anomalies, prepubertal short stature, brachydactyly, ophthalmologic and otolaryngologic abnormalities, peripheral neuropathy, developmental delay, cognitive impairment, and behavioral abnormalities that has_material_basis_in a 3.7-Mb interstitial deletion in chromosome 17p11.2 or sometimes by mutations in the RAI1 gene in the same region.", "url": "https://disease-ontology.org/term/DOID:0060768", "evidence": [ { "id": "0060768", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060768" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7T3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7T3" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7T3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7T3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4K7T3-1" }, { "uniprot_canonical_ac": "A0A0B4KEF0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEF0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEF0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 148, "chemical_mass": 17179.0, "gene_names": "mlncRNA42E5-2;CG43646;Dmel\\CG43646;Dmel_CG43646;lincRNA.258", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4KEF0-1" }, { "uniprot_canonical_ac": "A0A0B4KEL2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEL2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEL2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 281, "chemical_mass": 31416.0, "gene_names": "Dmel\\CG9084;CG9084;Dmel\\CG9084;Dmel_CG9084", "protein_name": "Phospholipid scramblase", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEL2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEL2" } ], "pmid": "" } ], "biological_process": [ { "name": "plasma membrane phospholipid scrambling", "id": "GO:0017121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017121", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEL2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEL2" } ], "pmid": "" } ], "molecular_function": [ { "name": "phospholipid scramblase activity", "id": "GO:0017128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017128", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEL2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEL2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4KEL2-1" }, { "uniprot_canonical_ac": "A0A0B4KES8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KES8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KES8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 60, "chemical_mass": 6855.0, "gene_names": "Dmel\\CG43789;CG43789;Dmel\\CG43789;Dmel_CG43789", "protein_name": "Seminal fluid protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4KES8-1" }, { "uniprot_canonical_ac": "A0A0B4KEV6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEV6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEV6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 412, "chemical_mass": 44028.0, "gene_names": "Dmel\\CG43711;CG43711;Dmel\\CG43711;Dmel_CG43711", "protein_name": "", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEV6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEV6" } ], "pmid": "" }, { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEV6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEV6" } ], "pmid": "" }, { "name": "nuclear localization sequence binding", "id": "GO:0008139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008139", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEV6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEV6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear pore cytoplasmic filaments", "id": "GO:0044614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044614", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEV6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEV6" } ], "pmid": "" } ], "biological_process": [ { "name": "post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery", "id": "GO:0000973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000973", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEV6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEV6" } ], "pmid": "" }, { "name": "telomere tethering at nuclear periphery", "id": "GO:0034398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034398", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEV6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEV6" } ], "pmid": "" }, { "name": "RNA export from nucleus", "id": "GO:0006405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006405", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEV6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEV6" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEV6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEV6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4KEV6-1" }, { "uniprot_canonical_ac": "A0A0B4KF06-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF06", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF06" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1055, "chemical_mass": 118793.0, "gene_names": "ValRS;Aats-val;BEST:LD45671;CG4062;Dmel\\CG4062;Dmel_CG4062;VARS;VRS;ValRS;aaRS(Val);aats-val;dVARS;l(2)03531;l(2)rI255;ld45671", "protein_name": "Valine--tRNA ligase", "disease": [ { "disease_id": "DOID:0060475", "name": "myoclonic-atonic epilepsy", "description": "An idiopathic generalized epilepsy characterized by onset of multiple seizure types in the first few years of life and associated with poor prognosis. Affected individuals have cognitive regression and intellectual disability and that has_material_basis_in heterozygous mutation in the SLC6A1 gene on chromosome 3p25.", "url": "https://disease-ontology.org/term/DOID:0060475", "evidence": [ { "id": "0060475", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060475" } ], "weight": 0.0 }, { "disease_id": "DOID:0111478", "name": "combined oxidative phosphorylation deficiency 20", "description": "A combined oxidative phosphorylation deficiency that has_material_basis_in homozygous or compound heterozygous mutation in the VARS2 gene on chromosome 6p21.33.", "url": "https://disease-ontology.org/term/DOID:0111478", "evidence": [ { "id": "0111478", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111478" } ], "weight": 0.0 }, { "disease_id": "DOID:700", "name": "mitochondrial metabolism disease", "description": "An inherited metabolic disorder that involves mitochondrial metabolism dysfunction.", "url": "https://disease-ontology.org/term/DOID:700", "evidence": [ { "id": "700", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:700" } ], "weight": 0.0 }, { "disease_id": "DOID:890", "name": "mitochondrial encephalomyopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:890", "evidence": [ { "id": "890", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:890" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "aminoacyl-tRNA deacylase activity", "id": "GO:0002161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002161", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF06", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF06" } ], "pmid": "" }, { "name": "valine-tRNA ligase activity", "id": "GO:0004832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004832", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF06", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF06" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF06", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF06" } ], "pmid": "" } ], "biological_process": [ { "name": "valyl-tRNA aminoacylation", "id": "GO:0006438", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006438", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF06", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF06" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF06", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF06" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF06", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF06" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4KF06-1" }, { "uniprot_canonical_ac": "A0A0B4KF09-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF09", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF09" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 340, "chemical_mass": 37074.0, "gene_names": "Dmel\\CG43710;CG43710;Dmel\\CG43710;Dmel_CG43710", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4KF09-1" }, { "uniprot_canonical_ac": "A0A0B4LGM5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGM5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGM5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1047, "chemical_mass": 116564.0, "gene_names": "Hcs;CG14670;Dmel\\CG14670;Dmel_CG14670;HCS;HSC;Hcs;NEST:bs27h05", "protein_name": "", "disease": [ { "disease_id": "DOID:859", "name": "holocarboxylase synthetase deficiency", "description": "A multiple carboxylase deficiency that involves a deficiency in holocarboxylase synthetase.", "url": "https://disease-ontology.org/term/DOID:859", "evidence": [ { "id": "859", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:859" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "biotin--[biotin carboxyl-carrier protein] ligase activity", "id": "GO:0004077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004077", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGM5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGM5" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGM5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGM5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGM5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGM5" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGM5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGM5" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGM5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGM5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4LGM5-1" }, { "uniprot_canonical_ac": "A0A0B4KFC4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 680, "chemical_mass": 73129.0, "gene_names": "rib;CG7230;Dmel\\CG7230;Dmel_CG7230;RIB;Rib;fus1;gene 5;rib", "protein_name": "", "disease": [], "biological_process": [ { "name": "hindgut morphogenesis", "id": "GO:0007442", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007442", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC4" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC4" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC4" } ], "pmid": "" }, { "name": "membrane organization", "id": "GO:0061024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061024", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC4" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC4" } ], "pmid": "" }, { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC4" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC4" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC4" } ], "pmid": "" }, { "name": "salivary gland development", "id": "GO:0007431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007431", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC4" } ], "pmid": "" }, { "name": "salivary gland morphogenesis", "id": "GO:0007435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007435", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC4" } ], "pmid": "" }, { "name": "gonad development", "id": "GO:0008406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008406", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC4" } ], "pmid": "" }, { "name": "establishment or maintenance of epithelial cell apical/basal polarity", "id": "GO:0045197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045197", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC4" } ], "pmid": "" }, { "name": "dorsal closure", "id": "GO:0007391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007391", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC4" } ], "pmid": "" }, { "name": "open tracheal system development", "id": "GO:0007424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007424", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC4" } ], "pmid": "" }, { "name": "tracheal outgrowth, open tracheal system", "id": "GO:0007426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007426", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC4" } ], "pmid": "" }, { "name": "epithelial cell migration, open tracheal system", "id": "GO:0007427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007427", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC4" } ], "pmid": "" }, { "name": "Malpighian tubule morphogenesis", "id": "GO:0007443", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007443", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC4" } ], "pmid": "" }, { "name": "head involution", "id": "GO:0008258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008258", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC4" } ], "pmid": "" }, { "name": "regulation of Malpighian tubule diameter", "id": "GO:0035297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035297", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC4" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4KFC4-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Thr141", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 141, "start_aa": "Thr", "end_pos": 141, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr141", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4KFC4-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Thr5", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 5, "start_aa": "Thr", "end_pos": 5, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr5", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A0A0B4KFC4-1" }, { "uniprot_canonical_ac": "A0A0B4KFK6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFK6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFK6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 582, "chemical_mass": 64311.0, "gene_names": "Dmel\\CG4630;CG4630;Dmel\\CG4630;Dmel_CG4630", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "disease": [ { "disease_id": "DOID:0050700", "name": "cardiomyopathy", "description": "A heart disease and a myopathy that is characterized by deterioration of the function of the heart muscle.", "url": "https://disease-ontology.org/term/DOID:0050700", "evidence": [ { "id": "0050700", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050700" } ], "weight": 0.0 }, { "disease_id": "DOID:0050908", "name": "myelodysplastic syndrome", "description": "A bone marrow cancer that is characterized by under production of white blood cells, red blood cells and platelets.", "url": "https://disease-ontology.org/term/DOID:0050908", "evidence": [ { "id": "0050908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050908" } ], "weight": 0.0 }, { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 }, { "disease_id": "DOID:14365", "name": "systemic primary carnitine deficiency disease", "description": "An amino acid metabolic disorder that involves defective proteins called carnitine transporters, which bring carnitine into cells and prevent its escape from the body preventing the body cannot utilize fats for energy.", "url": "https://disease-ontology.org/term/DOID:14365", "evidence": [ { "id": "14365", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14365" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 }, { "disease_id": "DOID:655", "name": "inherited metabolic disorder", "description": "A disease of metabolism that is characterized by enzyme deficiency or accumulation of enzymes or toxins which interfere with normal function due to inherited enzyme abnormality.", "url": "https://disease-ontology.org/term/DOID:655", "evidence": [ { "id": "655", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:655" } ], "weight": 0.0 }, { "disease_id": "DOID:7148", "name": "rheumatoid arthritis", "description": "An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint.", "url": "https://disease-ontology.org/term/DOID:7148", "evidence": [ { "id": "7148", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7148" } ], "weight": 0.0 }, { "disease_id": "DOID:8778", "name": "Crohn's disease", "description": "An intestinal disease that involves inflammation located_in intestine.", "url": "https://disease-ontology.org/term/DOID:8778", "evidence": [ { "id": "8778", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8778" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFK6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFK6" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFK6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFK6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4KFK6-1" }, { "uniprot_canonical_ac": "A0A0B4KFW6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFW6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFW6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 154, "chemical_mass": 17817.0, "gene_names": "Dmel\\CG43709;CG43709;Dmel\\CG43709;Dmel_CG43709", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4KFW6-1" }, { "uniprot_canonical_ac": "A0A0B4KG18-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KG18", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KG18" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 72, "chemical_mass": 8526.0, "gene_names": "Dmel\\CG43829;CG43829;Dmel\\CG43829;Dmel_CG43829", "protein_name": "Seminal fluid protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4KG18-1" }, { "uniprot_canonical_ac": "A0A0B4KG96-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KG96", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KG96" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 827, "chemical_mass": 92360.0, "gene_names": "hrg;CG9854;Dmel\\CG9854;Dmel_CG9854;Hiiragi;PAP;Pap;dHrg;hrg;l(2)07619;l(2)k07619", "protein_name": "polynucleotide adenylyltransferase", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KG96", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KG96" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KG96", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KG96" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KG96", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KG96" } ], "pmid": "" }, { "name": "poly(A) RNA polymerase activity", "id": "GO:1990817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990817", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KG96", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KG96" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KG96", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KG96" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KG96", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KG96" } ], "pmid": "" } ], "biological_process": [ { "name": "cytosolic mRNA polyadenylation", "id": "GO:0180011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180011", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KG96", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KG96" } ], "pmid": "" }, { "name": "co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway", "id": "GO:0180010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180010", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KG96", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KG96" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4KG96-1", "start_pos": "824", "end_pos": "824", "site_lbl": "Thr824", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 824, "start_aa": "Thr", "end_pos": 824, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr824", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A0A0B4KG96-1" }, { "uniprot_canonical_ac": "A0A0B4KGS4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGS4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGS4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 583, "chemical_mass": 65784.0, "gene_names": "Pak3;CG14895;D-Pak3;DPAK3;DPak3;DmPAK3;Dmel\\CG14895;Dmel_CG14895;Dpak3;PAK-3;PAK3;PaK3;Pak3;Pak;anon-WO0118547.285;dPAK3;dpak3;pak3", "protein_name": "non-specific serine/threonine protein kinase", "disease": [], "biological_process": [ { "name": "regulation of axonogenesis", "id": "GO:0050770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050770", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGS4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGS4" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGS4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGS4" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGS4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGS4" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGS4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGS4" } ], "pmid": "" }, { "name": "positive regulation of synapse assembly", "id": "GO:0051965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051965", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGS4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGS4" } ], "pmid": "" }, { "name": "myoblast fusion", "id": "GO:0007520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007520", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGS4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGS4" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGS4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGS4" } ], "pmid": "" }, { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGS4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGS4" } ], "pmid": "" }, { "name": "regulation of MAPK cascade", "id": "GO:0043408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043408", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGS4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGS4" } ], "pmid": "" }, { "name": "border follicle cell migration", "id": "GO:0007298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007298", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGS4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGS4" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGS4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGS4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGS4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGS4" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGS4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGS4" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGS4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGS4" } ], "pmid": "" }, { "name": "ruffle", "id": "GO:0001726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001726", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGS4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGS4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4KGS4-1" }, { "uniprot_canonical_ac": "A0A0B4KGX8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGX8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGX8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 420, "chemical_mass": 49207.0, "gene_names": "Dmel\\CG31102;CG10634;CG31102;Dmel\\CG31102;Dmel_CG31102;Dro9-0", "protein_name": "CHK kinase-like domain-containing protein", "disease": [], "molecular_function": [ { "name": "ecdysteroid 22-kinase activity", "id": "GO:0106389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106389", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGX8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGX8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4KGX8-1" }, { "uniprot_canonical_ac": "A0A0B4KH11-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KH11", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KH11" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 83, "chemical_mass": 8146.0, "gene_names": "Dmel\\CG44142;CG44142;Dmel\\CG44142;Dmel_CG44142", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4KH11-1" }, { "uniprot_canonical_ac": "A0A0B4KH75-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KH75", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KH75" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 237, "chemical_mass": 25897.0, "gene_names": "BcDNA:RE40372;BcDNA:RE40372;CG31446;Dmel\\CG31446;Dmel_CG31446", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4KH75-1" }, { "uniprot_canonical_ac": "A0A0B4KHM5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHM5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHM5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 493, "chemical_mass": 55316.0, "gene_names": "Dmel\\CG12783;CG12783;Dmel\\CG12783;Dmel_CG12783", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHM5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHM5" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHM5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHM5" } ], "pmid": "" } ], "biological_process": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHM5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHM5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4KHM5-1" }, { "uniprot_canonical_ac": "A0A0B4KI55-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI55", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI55" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 482, "chemical_mass": 53090.0, "gene_names": "Dmel\\CG7568;CG7568;Dmel\\CG7568;Dmel_CG7568", "protein_name": "Dynein assembly factor with WDR repeat domains 1", "disease": [ { "disease_id": "DOID:0050144", "name": "Kartagener syndrome", "description": "A primary ciliary dyskinesia that is characterized by sinusitis, bronchiectasis and situs inversus with dextrocardia resulting from dysfunction of the cilia during embryologic development.", "url": "https://disease-ontology.org/term/DOID:0050144", "evidence": [ { "id": "0050144", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050144" } ], "weight": 0.0 }, { "disease_id": "DOID:0050545", "name": "visceral heterotaxy", "description": "A physical disorder characterized by the abnormal distribution of the major visceral organs within the chest and abdomen.", "url": "https://disease-ontology.org/term/DOID:0050545", "evidence": [ { "id": "0050545", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050545" } ], "weight": 0.0 }, { "disease_id": "DOID:9562", "name": "primary ciliary dyskinesia", "description": "A ciliopathy that is characterized by impaired function of the cilia lining the respiratory tract (lower and upper, sinuses, Eustachian tube, middle ear) and fallopian tube.", "url": "https://disease-ontology.org/term/DOID:9562", "evidence": [ { "id": "9562", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9562" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI55", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI55" } ], "pmid": "" } ], "biological_process": [ { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI55", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI55" } ], "pmid": "" }, { "name": "axonemal dynein complex assembly", "id": "GO:0070286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070286", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI55", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI55" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI55", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI55" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4KI55-1" }, { "uniprot_canonical_ac": "A0A0B4LED6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LED6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LED6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 55, "chemical_mass": 6290.0, "gene_names": "lincRNA.249;CG44438;Dmel\\CG44438;Dmel_CG44438;lincRNA.249", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4LED6-1" }, { "uniprot_canonical_ac": "A1Z7M8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z7M8", "url": "https://www.uniprot.org/uniprotkb/A1Z7M8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 609, "chemical_mass": 70158.0, "gene_names": "Ance-4;Ance-4;CG8196;Dmel\\CG8196;Dmel_CG8196;ance-4", "protein_name": "Angiotensin-converting enzyme", "disease": [ { "disease_id": "DOID:0050152", "name": "aspiration pneumonia", "description": "A bacterial pneumonia which is an acute pulmonary inflammatory response that develops after the inhalation of colonized oropharyngeal material containing bacteria. It is seen in individuals with dysphagia and gastric dysmotility. The disease has_symptom tachypnea and has_symptom cough.", "url": "https://disease-ontology.org/term/DOID:0050152", "evidence": [ { "id": "0050152", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050152" } ], "weight": 0.0 }, { "disease_id": "DOID:0050848", "name": "obstructive sleep apnea", "description": "A sleep apnea that is characterized by repeated collapse and obstruction of the upper airway during sleep, which results in reduced airflow (hypopnea) or complete airflow cessation (apnea), oxygen desaturation, and arousals from sleep.", "url": "https://disease-ontology.org/term/DOID:0050848", "evidence": [ { "id": "0050848", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050848" } ], "weight": 0.0 }, { "disease_id": "DOID:0050855", "name": "renal fibrosis", "description": "A kidney disease that is characterized by progressive detrimental connective tissue deposition of the kidney parenchyma leading to deterioration of renal function.", "url": "https://disease-ontology.org/term/DOID:0050855", "evidence": [ { "id": "0050855", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050855" } ], "weight": 0.0 }, { "disease_id": "DOID:0050864", "name": "non-arteritic anterior ischemic optic neuropathy", "description": "An anterior ischemic optic neuropathy that is characterized by near-complete vision loss caused by acute ischemic damage to the optic nerve due to non-inflammatory small vessel disease.", "url": "https://disease-ontology.org/term/DOID:0050864", "evidence": [ { "id": "0050864", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050864" } ], "weight": 0.0 }, { "disease_id": "DOID:0051061", "name": "stroke", "description": "A cerebrovascular disease that is characterized by disruption of blood flow to the brain resulting in damage to brain cells due to a lack of oxygen.", "url": "https://disease-ontology.org/term/DOID:0051061", "evidence": [ { "id": "0051061", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051061" } ], "weight": 0.0 }, { "disease_id": "DOID:0060224", "name": "atrial fibrillation", "description": "A heart conduction disease that is characterized by uncoordinated electrical activity in the heart's upper chambers (the atria), which causes the heartbeat to become fast and irregular and has symptoms palpitations, weakness, fatigue, lightheadedness, dizziness, confusion, shortness of breath and chest pain.", "url": "https://disease-ontology.org/term/DOID:0060224", "evidence": [ { "id": "0060224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060224" } ], "weight": 0.0 }, { "disease_id": "DOID:0070658", "name": "alcohol-associated liver disease", "description": "A liver disease resulting from excessive alcohol intake.", "url": "https://disease-ontology.org/term/DOID:0070658", "evidence": [ { "id": "0070658", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070658" } ], "weight": 0.0 }, { "disease_id": "DOID:0080599", "name": "Coronavirus infectious disease", "description": "A viral infectious disease that has_material_basis_in Coronavirus.", "url": "https://disease-ontology.org/term/DOID:0080599", "evidence": [ { "id": "0080599", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080599" } ], "weight": 0.0 }, { "disease_id": "DOID:0080600", "name": "COVID-19", "description": "A Coronavirus infectious disease that is characterized by fever, cough and shortness of breath and that has_material_basis_in Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a subtype of Betacoronavirus pandemicum.", "url": "https://disease-ontology.org/term/DOID:0080600", "evidence": [ { "id": "0080600", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080600" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:10591", "name": "pre-eclampsia", "description": "A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy.", "url": "https://disease-ontology.org/term/DOID:10591", "evidence": [ { "id": "10591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10591" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10952", "name": "nephritis", "description": "A kidney disease that is characterized by an inflammation of the kidneys.", "url": "https://disease-ontology.org/term/DOID:10952", "evidence": [ { "id": "10952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10952" } ], "weight": 0.0 }, { "disease_id": "DOID:11123", "name": "IgA vasculitis", "description": "A hypersensitivity vasculitis that is characterized by purpura (purplish plaques), arthralgia, gastrointestinal upset, and/or glomerulonephritis, and may be related to increased immune response following an infection.", "url": "https://disease-ontology.org/term/DOID:11123", "evidence": [ { "id": "11123", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11123" } ], "weight": 0.0 }, { "disease_id": "DOID:11335", "name": "sarcoidosis", "description": "A hypersensitivity reaction type IV disease characterized by the growth of collections of inflammatory cells (granulomas) in multiple organs.", "url": "https://disease-ontology.org/term/DOID:11335", "evidence": [ { "id": "11335", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11335" } ], "weight": 0.0 }, { "disease_id": "DOID:11400", "name": "pyelonephritis", "description": "", "url": "https://disease-ontology.org/term/DOID:11400", "evidence": [ { "id": "11400", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11400" } ], "weight": 0.0 }, { "disease_id": "DOID:11713", "name": "diabetic angiopathy", "description": "A peripheral vascular disease that is characterized by narrowing of the arteries as a complication arising from chronic diabetes.", "url": "https://disease-ontology.org/term/DOID:11713", "evidence": [ { "id": "11713", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11713" } ], "weight": 0.0 }, { "disease_id": "DOID:1205", "name": "allergic disease", "description": "An immune system disease that is an exaggerated immune response to allergens, such as insect venom, dust mites, pollen, pet dander, drugs or some foods.", "url": "https://disease-ontology.org/term/DOID:1205", "evidence": [ { "id": "1205", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1205" } ], "weight": 0.0 }, { "disease_id": "DOID:1240", "name": "leukemia", "description": "A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells.", "url": "https://disease-ontology.org/term/DOID:1240", "evidence": [ { "id": "1240", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1240" } ], "weight": 0.0 }, { "disease_id": "DOID:12549", "name": "hepatitis A", "description": "A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in Hepatitis A virus (Hepatovirus ahepa), which is transmitted_by ingestion of contaminated food or water, or transmitted_by direct contact with an infected person. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice.", "url": "https://disease-ontology.org/term/DOID:12549", "evidence": [ { "id": "12549", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12549" } ], "weight": 0.0 }, { "disease_id": "DOID:13141", "name": "uveitis", "description": "An uveal disease is characterized by inflammation of any of the layers of the uvea of the eye, which includes the iris, ciliary body, and choroid.", "url": "https://disease-ontology.org/term/DOID:13141", "evidence": [ { "id": "13141", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13141" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:13241", "name": "Behcet's disease", "description": "An autoimmune disease that is characterized by mucocutaneous manifestations, including recurrent oral and genital ulcerations, ocular manifestations, especially chronic relapsing uveitis, and systemic vasculitis involving arteries and veins of all sizes.", "url": "https://disease-ontology.org/term/DOID:13241", "evidence": [ { "id": "13241", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13241" } ], "weight": 0.0 }, { "disease_id": "DOID:14115", "name": "toxic shock syndrome", "description": "A commensal bacterial infectious disease that results_in infection, has_material_basis_in Streptococcus pyogenes or has_material_basis_in Staphylococcus aureus, which produce toxins that are absorbed systemically and produce the systemic manifestations. The infection has_symptom fever, has_symptom rash, has_symptom hypotension, has_symptom multiorgan failure, has_symptom desquamation, has_symptom vomiting, has_symptom diarrhea, has_symptom headache, and has_symptom nonfocal neurologic abnormalities.", "url": "https://disease-ontology.org/term/DOID:14115", "evidence": [ { "id": "14115", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14115" } ], "weight": 0.0 }, { "disease_id": "DOID:14499", "name": "Fabry disease", "description": "A sphingolipidosis that is characterized by the buildup of globotriaosylceramide in the body's cells and has_material_basis_in X-linked inherited mutations in the GLA gene, encoding alpha-galactosidase A, on chromosome Xq22.", "url": "https://disease-ontology.org/term/DOID:14499", "evidence": [ { "id": "14499", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14499" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:2355", "name": "anemia", "description": "A hematopoietic system disease that is characterized by a decrease in the normal number of red blood cells.", "url": "https://disease-ontology.org/term/DOID:2355", "evidence": [ { "id": "2355", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2355" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:2986", "name": "IgA glomerulonephritis", "description": "A glomerulonephritis characterized by build up of IgA antibody in the glomerulus.", "url": "https://disease-ontology.org/term/DOID:2986", "evidence": [ { "id": "2986", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2986" } ], "weight": 0.0 }, { "disease_id": "DOID:2987", "name": "familial Mediterranean fever", "description": "An autoinflammatory disease characterized by recurrent episodes of fever and acute inflammation of the membranes lining the abdomen, joints and lungs; that has_material_basis_in mutations in the MEFV gene, which encodes the protein pyrin.", "url": "https://disease-ontology.org/term/DOID:2987", "evidence": [ { "id": "2987", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2987" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:3500", "name": "gallbladder adenocarcinoma", "description": "A gallbladder carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3500", "evidence": [ { "id": "3500", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3500" } ], "weight": 0.0 }, { "disease_id": "DOID:3526", "name": "cerebral infarction", "description": "A cerebrovascular disease that is characterized by an area of necrotic tissue in the brain resulting from a blockage or narrowing in the arteries supplying blood and oxygen to the brain.", "url": "https://disease-ontology.org/term/DOID:3526", "evidence": [ { "id": "3526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3526" } ], "weight": 0.0 }, { "disease_id": "DOID:3587", "name": "pancreatic ductal carcinoma", "description": "A pancreatic carcinoma located_in the pancreatic duct.", "url": "https://disease-ontology.org/term/DOID:3587", "evidence": [ { "id": "3587", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3587" } ], "weight": 0.0 }, { "disease_id": "DOID:3905", "name": "lung carcinoma", "description": "A lung cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells and is located_in the lungs and has_symptom cough and has_symptom chest discomfort or pain and has_symptom weight loss and has_symptom hemoptysis.", "url": "https://disease-ontology.org/term/DOID:3905", "evidence": [ { "id": "3905", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3905" } ], "weight": 0.0 }, { "disease_id": "DOID:4079", "name": "heart valve disease", "description": "A heart disease involving one or more of the four valves of the heart (the aortic and mitral valves on the left and the pulmonary and tricuspid valves on the right).", "url": "https://disease-ontology.org/term/DOID:4079", "evidence": [ { "id": "4079", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4079" } ], "weight": 0.0 }, { "disease_id": "DOID:418", "name": "systemic scleroderma", "description": "A scleroderma that is characterized by fibrosis (or hardening) of the skin and major organs, as well as vascular alterations, and autoantibodies.", "url": "https://disease-ontology.org/term/DOID:418", "evidence": [ { "id": "418", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:418" } ], "weight": 0.0 }, { "disease_id": "DOID:5082", "name": "liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:5082", "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:552", "name": "pneumonia", "description": "A lung disease that involves lung parenchyma or alveolar inflammation and abnormal alveolar filling with fluid (consolidation and exudation). It results from a variety of causes including infection with bacteria, viruses, fungi or parasites, and chemical or physical injury to the lungs. It is accompanied by fever, chills, cough, and difficulty in breathing.", "url": "https://disease-ontology.org/term/DOID:552", "evidence": [ { "id": "552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:552" } ], "weight": 0.0 }, { "disease_id": "DOID:576", "name": "proteinuria", "description": "A kidney disease that is characterized by the presence of excess proteins in the urine.", "url": "https://disease-ontology.org/term/DOID:576", "evidence": [ { "id": "576", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:576" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:61", "name": "mitral valve disease", "description": "", "url": "https://disease-ontology.org/term/DOID:61", "evidence": [ { "id": "61", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:61" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:7147", "name": "ankylosing spondylitis", "description": "An arthritis that results_in inflammation in the joints of the spine and pelvis. The disease has_symptom pain, has_symptom stiffness in the spine, has_symptom stiffness in the neck, has_symptom stiffness in the hips, has_symptom stiffness in the jaw and has_symptom stiffness in the rib cage.", "url": "https://disease-ontology.org/term/DOID:7147", "evidence": [ { "id": "7147", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7147" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 }, { "disease_id": "DOID:841", "name": "extrinsic allergic alveolitis", "description": "An interstitial lung disease involving inflammation of alveoli and smallest airways (bronchioles) of the lung caused by an allergic reaction to inhaled organic dusts containing microorganisms or proteins, and chemicals. Symptoms include chills, cough, fever, malaise, shortness of breath, loss of appetite and weight loss.", "url": "https://disease-ontology.org/term/DOID:841", "evidence": [ { "id": "841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:841" } ], "weight": 0.0 }, { "disease_id": "DOID:8432", "name": "polycythemia", "description": "A bone marrow disease characterized by an increased number of red blood cells in the bloodstream resulting in thicker blood and reduced blood flow.", "url": "https://disease-ontology.org/term/DOID:8432", "evidence": [ { "id": "8432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8432" } ], "weight": 0.0 }, { "disease_id": "DOID:8552", "name": "chronic myeloid leukemia", "description": "A myeloid leukemia that is characterized by over production of white blood cells.", "url": "https://disease-ontology.org/term/DOID:8552", "evidence": [ { "id": "8552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8552" } ], "weight": 0.0 }, { "disease_id": "DOID:8805", "name": "intermediate coronary syndrome", "description": "", "url": "https://disease-ontology.org/term/DOID:8805", "evidence": [ { "id": "8805", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8805" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 }, { "disease_id": "DOID:8970", "name": "subacute sclerosing panencephalitis", "description": "A viral encephalitis that has_material_basis_in persistent central nervous system infection of the wild-type measles virus (Morbillivirus hominis) characterized by onset of personality or behavioral changes and intellectual deterioriation years after initial infection, followed by progressive decline in motor function, akinetic mutism or coma, and death. Higher incidence or shorter latency periods may be observed in those initially infected under the age of 2 or in cases of intrafamilial transmission.", "url": "https://disease-ontology.org/term/DOID:8970", "evidence": [ { "id": "8970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8970" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9538", "name": "multiple myeloma", "description": "A myeloid neoplasm that is located_in the plasma cells in bone marrow.", "url": "https://disease-ontology.org/term/DOID:9538", "evidence": [ { "id": "9538", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9538" } ], "weight": 0.0 }, { "disease_id": "DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.", "url": "https://disease-ontology.org/term/DOID:9744", "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ], "weight": 0.0 }, { "disease_id": "DOID:9775", "name": "diastolic heart failure", "description": "", "url": "https://disease-ontology.org/term/DOID:9775", "evidence": [ { "id": "9775", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9775" } ], "weight": 0.0 }, { "disease_id": "DOID:988", "name": "mitral valve prolapse", "description": "A mitral valve disease where one or both of the cusps of the mitral valve bulge or collapse backward in the left atrium during systole.", "url": "https://disease-ontology.org/term/DOID:988", "evidence": [ { "id": "988", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:988" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A1Z7M8", "url": "https://www.uniprot.org/uniprotkb/A1Z7M8" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A1Z7M8", "url": "https://www.uniprot.org/uniprotkb/A1Z7M8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A1Z7M8", "url": "https://www.uniprot.org/uniprotkb/A1Z7M8" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A1Z7M8", "url": "https://www.uniprot.org/uniprotkb/A1Z7M8" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A1Z7M8", "url": "https://www.uniprot.org/uniprotkb/A1Z7M8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1Z7M8-1" }, { "uniprot_canonical_ac": "A1ZAP1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZAP1", "url": "https://www.uniprot.org/uniprotkb/A1ZAP1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 889, "chemical_mass": 99091.0, "gene_names": "Dmel\\CG9646;CG9646;Dmel\\CG9646;Dmel_CG9646", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1ZAP1-1", "start_pos": "440", "end_pos": "440", "site_lbl": "Thr440", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 440, "start_aa": "Thr", "end_pos": 440, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr440", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A1ZAP1-1" }, { "uniprot_canonical_ac": "A0A0B4LFY7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LFY7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LFY7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 138, "chemical_mass": 15719.0, "gene_names": "Dmel\\CG44622;CG44622;Dmel\\CG44622;Dmel_CG44622;lincRNA.354", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4LFY7-1" }, { "uniprot_canonical_ac": "A0A0B4LGL7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGL7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGL7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 86, "chemical_mass": 9588.0, "gene_names": "Dmel\\CG44812;CG44812;Dmel\\CG44812;Dmel_CG44812", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4LGL7-1" }, { "uniprot_canonical_ac": "A0A0B4LH86-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LH86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LH86" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 292, "chemical_mass": 32579.0, "gene_names": "Dmel\\CG13527;SPH182;CG13527;Dmel\\CG13527;Dmel_CG13527;SPH182", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LH86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LH86" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LH86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LH86" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LH86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LH86" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LH86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LH86" } ], "pmid": "" }, { "name": "serine-type peptidase activity", "id": "GO:0008236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008236", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LH86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LH86" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4LH86-1" }, { "uniprot_canonical_ac": "A0A0B4LHE5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHE5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHE5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 136, "chemical_mass": 15320.0, "gene_names": "pre-mod(mdg4)-P;CG44881;Dmel\\CG44881;Dmel_CG44881;pre-mod(mdg4)-P", "protein_name": "", "disease": [], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHE5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHE5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4LHE5-1" }, { "uniprot_canonical_ac": "A0A0B4LID7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LID7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LID7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 679, "chemical_mass": 71652.0, "gene_names": "ClpX;CG4538;ClpX;Clpx;Dmel\\CG4538;Dmel_CG4538", "protein_name": "", "disease": [ { "disease_id": "DOID:13270", "name": "erythropoietic protoporphyria", "description": "An acute porphyria characterized by a deficiency in the enzyme ferrochelatase, leading to abnormally high levels of protoporphyrin in the tissue.", "url": "https://disease-ontology.org/term/DOID:13270", "evidence": [ { "id": "13270", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13270" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LID7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LID7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LID7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LID7" } ], "pmid": "" }, { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LID7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LID7" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LID7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LID7" } ], "pmid": "" }, { "name": "peptidase activity", "id": "GO:0008233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008233", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LID7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LID7" } ], "pmid": "" }, { "name": "ATP-dependent protein folding chaperone", "id": "GO:0140662", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140662", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LID7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LID7" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LID7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LID7" } ], "pmid": "" }, { "name": "mitochondrial endopeptidase Clp complex", "id": "GO:0009841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009841", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LID7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LID7" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis involved in protein catabolic process", "id": "GO:0051603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051603", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LID7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LID7" } ], "pmid": "" }, { "name": "mitochondrial protein quality control", "id": "GO:0141164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141164", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LID7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LID7" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LID7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LID7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A0B4LID7-1" }, { "uniprot_canonical_ac": "A0A0C4DHF5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0C4DHF5", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DHF5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 556, "chemical_mass": 62371.0, "gene_names": "mtg;0849/10;10;CG7549;Dmel\\CG7549;Dmel_CG7549;MTG;Mtg;l(3)S084910b;l(3)S084910;mtg", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A0C4DHF5", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DHF5" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A0C4DHF5", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DHF5" } ], "pmid": "" }, { "name": "terminal bouton", "id": "GO:0043195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043195", "evidence": [ { "database": "UniProtKB", "id": "A0A0C4DHF5", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DHF5" } ], "pmid": "" }, { "name": "synaptic cleft", "id": "GO:0043083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043083", "evidence": [ { "database": "UniProtKB", "id": "A0A0C4DHF5", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DHF5" } ], "pmid": "" } ], "biological_process": [ { "name": "synapse assembly", "id": "GO:0007416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007416", "evidence": [ { "database": "UniProtKB", "id": "A0A0C4DHF5", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DHF5" } ], "pmid": "" } ], "molecular_function": [ { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "A0A0C4DHF5", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DHF5" } ], "pmid": "" }, { "name": "carbohydrate derivative binding", "id": "GO:0097367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097367", "evidence": [ { "database": "UniProtKB", "id": "A0A0C4DHF5", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DHF5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0C4DHF5-1", "start_pos": "202", "end_pos": "202", "site_lbl": "Thr202", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 202, "start_aa": "Thr", "end_pos": 202, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr202", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A0A0C4DHF5-1" }, { "uniprot_canonical_ac": "A0A126GV02-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A126GV02", "url": "https://www.uniprot.org/uniprotkb/A0A126GV02" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 85, "chemical_mass": 10012.0, "gene_names": "pre-mod(mdg4)-AA;CG45988;Dmel\\CG45988;Dmel_CG45988;pre-mod(mdg4)-AA", "protein_name": "", "disease": [], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A126GV02", "url": "https://www.uniprot.org/uniprotkb/A0A126GV02" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A126GV02-1" }, { "uniprot_canonical_ac": "A0A1W5PXS3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A1W5PXS3", "url": "https://www.uniprot.org/uniprotkb/A0A1W5PXS3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 36, "chemical_mass": 4310.0, "gene_names": "Dmel\\CG43645;CG43645;Dmel\\CG43645;Dmel_CG43645;mlncRNA36C10", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A1W5PXS3-1" }, { "uniprot_canonical_ac": "A0A1Z1CGY8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A1Z1CGY8", "url": "https://www.uniprot.org/uniprotkb/A0A1Z1CGY8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 40, "chemical_mass": 4745.0, "gene_names": "Dmel\\CG46311;CG46311;Dmel\\CG46311;Dmel_CG46311;Tango13-5'utr", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A1Z1CGY8-1" }, { "uniprot_canonical_ac": "A0A1Z1CK60-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A1Z1CK60", "url": "https://www.uniprot.org/uniprotkb/A0A1Z1CK60" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 22, "chemical_mass": 2636.0, "gene_names": "CG13627-5'utr;CG13627-5'utr;CG46316;Dmel\\CG46316;Dmel_CG46316", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A1Z1CK60-1" }, { "uniprot_canonical_ac": "A0A2U8U1T7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A2U8U1T7", "url": "https://www.uniprot.org/uniprotkb/A0A2U8U1T7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 23, "chemical_mass": 2640.0, "gene_names": "Dmel\\CG46335;CG46335;CR43476;Dmel_CG46335", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A2U8U1T7-1" }, { "uniprot_canonical_ac": "A0A4D6K4K3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K4K3", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K4K3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 145, "chemical_mass": 16273.0, "gene_names": "Dmel\\CG46387;CG46387;Dmel_CG46387", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A4D6K4K3-1" }, { "uniprot_canonical_ac": "A0A4D6K5M0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K5M0", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K5M0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1401, "chemical_mass": 158822.0, "gene_names": "Gmap;CG32587;CG33206;CG6350;CG7821;Dmel\\CG33206;Dmel_CG33206;GMAP-210;GMAP210;GMAP;Gmap;dGMAP;l(1)G0168", "protein_name": "", "disease": [ { "disease_id": "DOID:0080054", "name": "achondrogenesis type IA", "description": "An achondrogenesis that results_in abnormal ossification of the located_in vertebral column or located_in spine.", "url": "https://disease-ontology.org/term/DOID:0080054", "evidence": [ { "id": "0080054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080054" } ], "weight": 0.0 }, { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K5M0", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K5M0" } ], "pmid": "" }, { "name": "cis-Golgi network membrane", "id": "GO:0033106", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033106", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K5M0", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K5M0" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K5M0", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K5M0" } ], "pmid": "" }, { "name": "Golgi stack", "id": "GO:0005795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005795", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K5M0", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K5M0" } ], "pmid": "" }, { "name": "Golgi cis cisterna", "id": "GO:0000137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000137", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K5M0", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K5M0" } ], "pmid": "" } ], "biological_process": [ { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K5M0", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K5M0" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K5M0", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K5M0" } ], "pmid": "" }, { "name": "vesicle tethering to Golgi", "id": "GO:0099041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099041", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K5M0", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K5M0" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K5M0", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K5M0" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K5M0", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K5M0" } ], "pmid": "" } ], "molecular_function": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K5M0", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K5M0" } ], "pmid": "" }, { "name": "cargo receptor activity", "id": "GO:0038024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038024", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K5M0", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K5M0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A4D6K5M0-1" }, { "uniprot_canonical_ac": "A8JPC8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JPC8", "url": "https://www.uniprot.org/uniprotkb/A8JPC8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1519, "chemical_mass": 163615.0, "gene_names": "CG15566;Dmel\\CG34347;EST:LP08211;CG11339;CG15566;CG34347;Dmel\\CG34347;Dmel_CG34347;EST:LP08211;LP8211", "protein_name": "Erythrocyte membrane protein band 4.1-like 4A", "disease": [], "cellular_component": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A8JPC8", "url": "https://www.uniprot.org/uniprotkb/A8JPC8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A8JPC8", "url": "https://www.uniprot.org/uniprotkb/A8JPC8" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "A8JPC8", "url": "https://www.uniprot.org/uniprotkb/A8JPC8" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "A8JPC8", "url": "https://www.uniprot.org/uniprotkb/A8JPC8" } ], "pmid": "" } ], "biological_process": [ { "name": "animal organ morphogenesis", "id": "GO:0009887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887", "evidence": [ { "database": "UniProtKB", "id": "A8JPC8", "url": "https://www.uniprot.org/uniprotkb/A8JPC8" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "A8JPC8", "url": "https://www.uniprot.org/uniprotkb/A8JPC8" } ], "pmid": "" }, { "name": "actomyosin structure organization", "id": "GO:0031032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031032", "evidence": [ { "database": "UniProtKB", "id": "A8JPC8", "url": "https://www.uniprot.org/uniprotkb/A8JPC8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8JPC8-1" }, { "uniprot_canonical_ac": "A0A6H2EFP8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EFP8", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EFP8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 65, "chemical_mass": 7232.0, "gene_names": "lncRNA:CR45207;CG45207;CR45207;Dmel\\CG45207;Dmel_CG45207", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A6H2EFP8-1" }, { "uniprot_canonical_ac": "A0A6H2EJK0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJK0", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJK0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 523, "chemical_mass": 57534.0, "gene_names": "Eaat1;AF001784;CG3747;Dglt-1;Dglut-1;Dmel\\CG3747;Dmel_CG3747;EAAT1;EAAT;Eaat 1;Eaat1;GLUT;dEAAT1;dEAAT;dEaat1;eaat1", "protein_name": "Amino acid transporter", "disease": [ { "disease_id": "DOID:0050865", "name": "tongue squamous cell carcinoma", "description": "A head and neck squamous cell carcinoma that is located_in the tongue.", "url": "https://disease-ontology.org/term/DOID:0050865", "evidence": [ { "id": "0050865", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050865" } ], "weight": 0.0 }, { "disease_id": "DOID:0050994", "name": "episodic ataxia type 6", "description": "An episodic ataxia that is characterized by nystagmus and dysarthria, and has_material_basis_in autosomal dominant inheritance of mutation in the SLC1A3 gene.", "url": "https://disease-ontology.org/term/DOID:0050994", "evidence": [ { "id": "0050994", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050994" } ], "weight": 0.0 }, { "disease_id": "DOID:0060650", "name": "dicarboxylic aminoaciduria", "description": "An amino acid metabolic disorder that is characterized by an excess urinary excretion of aspartate and glutamate acidic amino acids.", "url": "https://disease-ontology.org/term/DOID:0060650", "evidence": [ { "id": "0060650", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060650" } ], "weight": 0.0 }, { "disease_id": "DOID:0070093", "name": "schizophrenia 18", "description": "A schizophrenia that has_material_basis_in a mutation of the SLC1A1 gene on chromosome 9p24.2.", "url": "https://disease-ontology.org/term/DOID:0070093", "evidence": [ { "id": "0070093", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070093" } ], "weight": 0.0 }, { "disease_id": "DOID:0070537", "name": "spastic tetraplegia, thin corpus callosum, and progressive microcephaly", "description": "An autosomal recessive intellectual developmental disorder characterized by neonatal or infantile onset of spastic tetraplegia, thin corpus callosum, progressive microcephaly, and severely impaired global development that has_material_basis_in homozygous or compound heterozygous mutation in the SLC1A4 gene on chromosome 2p14.", "url": "https://disease-ontology.org/term/DOID:0070537", "evidence": [ { "id": "0070537", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070537" } ], "weight": 0.0 }, { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:13544", "name": "low tension glaucoma", "description": "An open-angle glaucoma characterized by increased intrinsic resistance to aqueous outflow without known secondary causes, an anatomically narrow anterior chamber angle, or elevated intraocular pressure compared to the average population. Normal tension glaucoma has_symptom progressive decreased vision and progressive loss of peripheral vision.", "url": "https://disease-ontology.org/term/DOID:13544", "evidence": [ { "id": "13544", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13544" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:4752", "name": "multiple system atrophy", "description": "", "url": "https://disease-ontology.org/term/DOID:4752", "evidence": [ { "id": "4752", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4752" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJK0", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJK0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJK0", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJK0" } ], "pmid": "" }, { "name": "terminal bouton", "id": "GO:0043195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043195", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJK0", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJK0" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJK0", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJK0" } ], "pmid": "" } ], "molecular_function": [ { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJK0", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJK0" } ], "pmid": "" }, { "name": "neutral L-amino acid transmembrane transporter activity", "id": "GO:0015175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015175", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJK0", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJK0" } ], "pmid": "" }, { "name": "glutamate:sodium symporter activity", "id": "GO:0015501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015501", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJK0", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJK0" } ], "pmid": "" }, { "name": "L-glutamate transmembrane transporter activity", "id": "GO:0005313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005313", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJK0", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJK0" } ], "pmid": "" }, { "name": "L-aspartate transmembrane transporter activity", "id": "GO:0015183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015183", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJK0", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJK0" } ], "pmid": "" } ], "biological_process": [ { "name": "L-alpha-amino acid transmembrane transport", "id": "GO:1902475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902475", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJK0", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJK0" } ], "pmid": "" }, { "name": "regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction", "id": "GO:0014853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014853", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJK0", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJK0" } ], "pmid": "" }, { "name": "adult locomotory behavior", "id": "GO:0008344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008344", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJK0", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJK0" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJK0", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJK0" } ], "pmid": "" }, { "name": "aspartate transmembrane transport", "id": "GO:0015810", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015810", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJK0", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJK0" } ], "pmid": "" }, { "name": "L-glutamate transmembrane transport", "id": "GO:0015813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015813", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJK0", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJK0" } ], "pmid": "" }, { "name": "larval locomotory behavior", "id": "GO:0008345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008345", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJK0", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJK0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A6H2EJK0-1" }, { "uniprot_canonical_ac": "A0A6H2EJE4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJE4", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJE4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 65, "chemical_mass": 7285.0, "gene_names": "Dmel\\CG46397;CG46397;Dmel_CG46397", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A6H2EJE4-1" }, { "uniprot_canonical_ac": "A0A6M3Q7P0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q7P0", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q7P0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 185, "chemical_mass": 21475.0, "gene_names": "Dmel\\CG46430;CG46430;Dmel_CG46430", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A6M3Q7P0-1" }, { "uniprot_canonical_ac": "A0A6M3Q7S6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q7S6", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q7S6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 268, "chemical_mass": 30816.0, "gene_names": "lncRNA:CR43428;CG12865;CG43428;CR43428;Dmel\\CG43428;Dmel_CG43428", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A6M3Q7S6-1", "start_pos": "171", "end_pos": "171", "site_lbl": "Thr171", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 171, "start_aa": "Thr", "end_pos": 171, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr171", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A0A6M3Q7S6-1" }, { "uniprot_canonical_ac": "A0A6M3Q8Y2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q8Y2", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q8Y2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 943, "chemical_mass": 104941.0, "gene_names": "bma;CG12524;CG14163;CG34356;Dmel\\CG34356;Dmel_CG34356;bma", "protein_name": "", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q8Y2", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q8Y2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A6M3Q8Y2-1", "start_pos": "747", "end_pos": "747", "site_lbl": "Thr747", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 747, "start_aa": "Thr", "end_pos": 747, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr747", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A0A6M3Q8Y2-1" }, { "uniprot_canonical_ac": "A0A6M3QAV0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6M3QAV0", "url": "https://www.uniprot.org/uniprotkb/A0A6M3QAV0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 161, "chemical_mass": 19002.0, "gene_names": "Dmel\\CG46443;CG46443;Dmel_CG46443", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A6M3QAV0-1" }, { "uniprot_canonical_ac": "A0A6M3QHP2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6M3QHP2", "url": "https://www.uniprot.org/uniprotkb/A0A6M3QHP2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 110, "chemical_mass": 12134.0, "gene_names": "Dmel\\CG46398;CG46398;Dmel_CG46398", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A0A6M3QHP2-1" }, { "uniprot_canonical_ac": "A1Z6I3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z6I3", "url": "https://www.uniprot.org/uniprotkb/A1Z6I3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2140, "chemical_mass": 234758.0, "gene_names": "Dmel\\CG43366;CG12551;CG14470;CG43366;Dmel\\CG43366;Dmel_CG43366", "protein_name": "Serpin domain-containing protein", "disease": [ { "disease_id": "DOID:0050117", "name": "disease by infectious agent", "description": "A disease that is the consequence of the presence of pathogenic microbial agents, including pathogenic viruses, pathogenic bacteria, fungi, protozoa, multicellular parasites, and aberrant proteins known as prions.", "url": "https://disease-ontology.org/term/DOID:0050117", "evidence": [ { "id": "0050117", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050117" } ], "weight": 0.0 }, { "disease_id": "DOID:0080547", "name": "metabolic dysfunction-associated steatohepatitis", "description": "A metabolic dysfunction-associated steatotic liver disease characterized by the presence of inflammation with hepatocyte injury such as ballooning, with or without fibrosis.", "url": "https://disease-ontology.org/term/DOID:0080547", "evidence": [ { "id": "0080547", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080547" } ], "weight": 0.0 }, { "disease_id": "DOID:0090030", "name": "corticosteroid-binding globulin deficiency", "description": "An adrenal gland disease characterized by decreased levels of serum corticosteroid-binding globulin and cortisol, and in some cases hypo- or hypertension, and muscle fatigue that has_material_basis_in heterozygous or homozygous mutation in the SERPINA6 gene on chromosome 14q32.", "url": "https://disease-ontology.org/term/DOID:0090030", "evidence": [ { "id": "0090030", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090030" } ], "weight": 0.0 }, { "disease_id": "DOID:0110350", "name": "osteogenesis imperfecta type 6", "description": "An osteogenesis imperfecta that has_material_basis_in mutation in the SERPINF1 gene on chromosome 17p13.3.", "url": "https://disease-ontology.org/term/DOID:0110350", "evidence": [ { "id": "0110350", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110350" } ], "weight": 0.0 }, { "disease_id": "DOID:0111901", "name": "heparin cofactor II deficiency", "description": "A thrombophilia characterized by increased risk of thromboembolism that has_material_basis_in heterozygous mutation in the HCF2 gene on chromosome 22q11.21.", "url": "https://disease-ontology.org/term/DOID:0111901", "evidence": [ { "id": "0111901", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111901" } ], "weight": 0.0 }, { "disease_id": "DOID:10584", "name": "retinitis pigmentosa", "description": "A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.", "url": "https://disease-ontology.org/term/DOID:10584", "evidence": [ { "id": "10584", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10584" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:1074", "name": "kidney failure", "description": "A kidney disease characterized by the failure of the kidneys to adequately filter waste products from the blood.", "url": "https://disease-ontology.org/term/DOID:1074", "evidence": [ { "id": "1074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1074" } ], "weight": 0.0 }, { "disease_id": "DOID:11168", "name": "anogenital venereal wart", "description": "A viral infectious disease that results_in infection located_in skin of vagina, cervix, uterus, anus, penis, scrotum, mouth, or throat, has_material_basis_in human papillomaviruses (types 6 and 11), which are transmitted_by direct contact with the skin during oral, genital, or anal sex with an infected partner. The infection has_symptom anogenital warts.", "url": "https://disease-ontology.org/term/DOID:11168", "evidence": [ { "id": "11168", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11168" } ], "weight": 0.0 }, { "disease_id": "DOID:11382", "name": "corneal neovascularization", "description": "", "url": "https://disease-ontology.org/term/DOID:11382", "evidence": [ { "id": "11382", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11382" } ], "weight": 0.0 }, { "disease_id": "DOID:11446", "name": "sciatic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:11446", "evidence": [ { "id": "11446", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11446" } ], "weight": 0.0 }, { "disease_id": "DOID:12986", "name": "leukostasis", "description": "", "url": "https://disease-ontology.org/term/DOID:12986", "evidence": [ { "id": "12986", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12986" } ], "weight": 0.0 }, { "disease_id": "DOID:13141", "name": "uveitis", "description": "An uveal disease is characterized by inflammation of any of the layers of the uvea of the eye, which includes the iris, ciliary body, and choroid.", "url": "https://disease-ontology.org/term/DOID:13141", "evidence": [ { "id": "13141", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13141" } ], "weight": 0.0 }, { "disease_id": "DOID:13207", "name": "proliferative diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:13207", "evidence": [ { "id": "13207", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13207" } ], "weight": 0.0 }, { "disease_id": "DOID:13514", "name": "venous tributary occlusion of retina", "description": "", "url": "https://disease-ontology.org/term/DOID:13514", "evidence": [ { "id": "13514", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13514" } ], "weight": 0.0 }, { "disease_id": "DOID:14018", "name": "alcoholic liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:14018", "evidence": [ { "id": "14018", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14018" } ], "weight": 0.0 }, { "disease_id": "DOID:14115", "name": "toxic shock syndrome", "description": "A commensal bacterial infectious disease that results_in infection, has_material_basis_in Streptococcus pyogenes or has_material_basis_in Staphylococcus aureus, which produce toxins that are absorbed systemically and produce the systemic manifestations. The infection has_symptom fever, has_symptom rash, has_symptom hypotension, has_symptom multiorgan failure, has_symptom desquamation, has_symptom vomiting, has_symptom diarrhea, has_symptom headache, and has_symptom nonfocal neurologic abnormalities.", "url": "https://disease-ontology.org/term/DOID:14115", "evidence": [ { "id": "14115", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14115" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:1459", "name": "hypothyroidism", "description": "A thyroid gland disease which involves an underproduction of thyroid hormone.", "url": "https://disease-ontology.org/term/DOID:1459", "evidence": [ { "id": "1459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1459" } ], "weight": 0.0 }, { "disease_id": "DOID:1727", "name": "retinal vein occlusion", "description": "", "url": "https://disease-ontology.org/term/DOID:1727", "evidence": [ { "id": "1727", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1727" } ], "weight": 0.0 }, { "disease_id": "DOID:2154", "name": "nephroblastoma", "description": "A kidney cancer that affects the kidneys and typically occuring in children.", "url": "https://disease-ontology.org/term/DOID:2154", "evidence": [ { "id": "2154", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2154" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:289", "name": "endometriosis", "description": "A female reproductive system disease characterized by the growth of endometrial tissue outside the uterine body.", "url": "https://disease-ontology.org/term/DOID:289", "evidence": [ { "id": "289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:289" } ], "weight": 0.0 }, { "disease_id": "DOID:332", "name": "amyotrophic lateral sclerosis", "description": "A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.", "url": "https://disease-ontology.org/term/DOID:332", "evidence": [ { "id": "332", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:332" } ], "weight": 0.0 }, { "disease_id": "DOID:3347", "name": "osteosarcoma", "description": "A bone sarcoma that is located_in bone that has_material_basis_in cells of mesenchymal origin. It usually involves bones and less frequently extraosseous sites. It often involves the long bones (particularly distal femur, proximal tibia, and proximal humerus).", "url": "https://disease-ontology.org/term/DOID:3347", "evidence": [ { "id": "3347", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3347" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:4448", "name": "macular degeneration", "description": "A retinal degeneration characterized by gradual deterioration of light-sensing cells in the tissues at the back of the eye and has_symptom vision loss.", "url": "https://disease-ontology.org/term/DOID:4448", "evidence": [ { "id": "4448", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4448" } ], "weight": 0.0 }, { "disease_id": "DOID:4449", "name": "macular retinal edema", "description": "", "url": "https://disease-ontology.org/term/DOID:4449", "evidence": [ { "id": "4449", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4449" } ], "weight": 0.0 }, { "disease_id": "DOID:4724", "name": "brain edema", "description": "A brain disease that is characterized by excess accumulation of fluid in the intracellular and/or extracellular spaces of the brain, has_symptom nausea, has_symptom vomiting, has_symptom blurred vision, has_symptom seizure, has_symptom coma.", "url": "https://disease-ontology.org/term/DOID:4724", "evidence": [ { "id": "4724", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4724" } ], "weight": 0.0 }, { "disease_id": "DOID:5052", "name": "melioidosis", "description": "A primary bacterial infectious disease that results_in infection, has_material_basis_in Burkholderia pseudomallei, which is transmitted_by contact with the contaminated water or soil. The infection has_symptom fever, has_symptom respiratory distress, has_symptom chest pain, and has_symptom stomach pain.", "url": "https://disease-ontology.org/term/DOID:5052", "evidence": [ { "id": "5052", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5052" } ], "weight": 0.0 }, { "disease_id": "DOID:5425", "name": "ovarian hyperstimulation syndrome", "description": "An ovarian disease that is characterized by cystic enlargement of the ovaries and a fluid shift from the intravascular to the third space and has_symptom abdominal pain, has_symptom nausea and has_symptom vomiting. This disease is an iatrogenic complication of assisted reproduction technology.", "url": "https://disease-ontology.org/term/DOID:5425", "evidence": [ { "id": "5425", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5425" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:768", "name": "retinoblastoma", "description": "A retinal cell cancer and malignant neoplasm of retina and neuroblastoma and neuroendocrine tumors that derives_from the tissues of the retina.", "url": "https://disease-ontology.org/term/DOID:768", "evidence": [ { "id": "768", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:768" } ], "weight": 0.0 }, { "disease_id": "DOID:7998", "name": "hyperthyroidism", "description": "A thyroid gland disease that involves an over production of thyroid hormone.", "url": "https://disease-ontology.org/term/DOID:7998", "evidence": [ { "id": "7998", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7998" } ], "weight": 0.0 }, { "disease_id": "DOID:8466", "name": "retinal degeneration", "description": "A retinal disease that is characterized by deterioration of the retina caused by the progressive and eventual death of the cells of the retina.", "url": "https://disease-ontology.org/term/DOID:8466", "evidence": [ { "id": "8466", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8466" } ], "weight": 0.0 }, { "disease_id": "DOID:8544", "name": "chronic fatigue syndrome", "description": "A syndrome that involves prolonged and severe tiredness or weariness that is unrelated to exertion, is not relieved by rest and for a minimum of six months and is not directly caused by other conditions.", "url": "https://disease-ontology.org/term/DOID:8544", "evidence": [ { "id": "8544", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8544" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9719", "name": "neovascular inflammatory vitreoretinopathy", "description": "A retinal and vitreous disease characterized by ocular inflammation, vascular dropout, large spots of hyperpigmentation, neovascularization of the peripheral and posterior retina, vitreous hemorrhage, and retinal detachment that has_material_basis_in heterozygous mutation in the CAPN5 gene on chromosome 11q13.5.", "url": "https://disease-ontology.org/term/DOID:9719", "evidence": [ { "id": "9719", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9719" } ], "weight": 0.0 }, { "disease_id": "DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.", "url": "https://disease-ontology.org/term/DOID:9744", "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A1Z6I3", "url": "https://www.uniprot.org/uniprotkb/A1Z6I3" } ], "pmid": "" } ], "molecular_function": [ { "name": "peptidase inhibitor activity", "id": "GO:0030414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030414", "evidence": [ { "database": "UniProtKB", "id": "A1Z6I3", "url": "https://www.uniprot.org/uniprotkb/A1Z6I3" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of immune response", "id": "GO:0050776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050776", "evidence": [ { "database": "UniProtKB", "id": "A1Z6I3", "url": "https://www.uniprot.org/uniprotkb/A1Z6I3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1Z6I3-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Thr20", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 20, "start_aa": "Thr", "end_pos": 20, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr20", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A1Z6I3-1", "start_pos": "313", "end_pos": "313", "site_lbl": "Thr313", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 313, "start_aa": "Thr", "end_pos": 313, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr313", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A1Z6I3-1" }, { "uniprot_canonical_ac": "A1Z6J2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z6J2", "url": "https://www.uniprot.org/uniprotkb/A1Z6J2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1276, "chemical_mass": 142495.0, "gene_names": "SCAP;CG14592;CG33131;CG8356;Dmel\\CG33131;Dmel_CG33131;SCAP;Scap_Dm;Scap;dSCAP;dScap;dscap", "protein_name": "Sterol regulatory element-binding protein cleavage-activating protein", "disease": [ { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A1Z6J2", "url": "https://www.uniprot.org/uniprotkb/A1Z6J2" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A1Z6J2", "url": "https://www.uniprot.org/uniprotkb/A1Z6J2" } ], "pmid": "" }, { "name": "ER to Golgi transport vesicle membrane", "id": "GO:0012507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012507", "evidence": [ { "database": "UniProtKB", "id": "A1Z6J2", "url": "https://www.uniprot.org/uniprotkb/A1Z6J2" } ], "pmid": "" }, { "name": "SREBP-SCAP complex", "id": "GO:0032936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032936", "evidence": [ { "database": "UniProtKB", "id": "A1Z6J2", "url": "https://www.uniprot.org/uniprotkb/A1Z6J2" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A1Z6J2", "url": "https://www.uniprot.org/uniprotkb/A1Z6J2" } ], "pmid": "" }, { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "A1Z6J2", "url": "https://www.uniprot.org/uniprotkb/A1Z6J2" } ], "pmid": "" }, { "name": "cholesterol metabolic process", "id": "GO:0008203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008203", "evidence": [ { "database": "UniProtKB", "id": "A1Z6J2", "url": "https://www.uniprot.org/uniprotkb/A1Z6J2" } ], "pmid": "" }, { "name": "regulation of cholesterol biosynthetic process", "id": "GO:0045540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045540", "evidence": [ { "database": "UniProtKB", "id": "A1Z6J2", "url": "https://www.uniprot.org/uniprotkb/A1Z6J2" } ], "pmid": "" }, { "name": "SREBP signaling pathway", "id": "GO:0032933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032933", "evidence": [ { "database": "UniProtKB", "id": "A1Z6J2", "url": "https://www.uniprot.org/uniprotkb/A1Z6J2" } ], "pmid": "" } ], "molecular_function": [ { "name": "sterol binding", "id": "GO:0032934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032934", "evidence": [ { "database": "UniProtKB", "id": "A1Z6J2", "url": "https://www.uniprot.org/uniprotkb/A1Z6J2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1Z6J2-1" }, { "uniprot_canonical_ac": "A1Z6N3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z6N3", "url": "https://www.uniprot.org/uniprotkb/A1Z6N3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 352, "chemical_mass": 40249.0, "gene_names": "Dmel\\CG15909;CG15909;Dmel\\CG15909;Dmel_CG15909", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1Z6N3-1" }, { "uniprot_canonical_ac": "A1Z6P0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z6P0", "url": "https://www.uniprot.org/uniprotkb/A1Z6P0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 310, "chemical_mass": 34344.0, "gene_names": "Zip42C.2;CG9430;Dmel\\CG9430;Dmel_CG9430;ZIP42C.2;Zip42C.2;cg9430;dZIP2;dZIP42C.2;dZip2;dZip42C.2", "protein_name": "", "disease": [], "biological_process": [ { "name": "detoxification of zinc ion", "id": "GO:0010312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010312", "evidence": [ { "database": "UniProtKB", "id": "A1Z6P0", "url": "https://www.uniprot.org/uniprotkb/A1Z6P0" } ], "pmid": "" }, { "name": "zinc ion transmembrane transport", "id": "GO:0071577", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071577", "evidence": [ { "database": "UniProtKB", "id": "A1Z6P0", "url": "https://www.uniprot.org/uniprotkb/A1Z6P0" } ], "pmid": "" }, { "name": "zinc ion import across plasma membrane", "id": "GO:0071578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071578", "evidence": [ { "database": "UniProtKB", "id": "A1Z6P0", "url": "https://www.uniprot.org/uniprotkb/A1Z6P0" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion transmembrane transporter activity", "id": "GO:0005385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005385", "evidence": [ { "database": "UniProtKB", "id": "A1Z6P0", "url": "https://www.uniprot.org/uniprotkb/A1Z6P0" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A1Z6P0", "url": "https://www.uniprot.org/uniprotkb/A1Z6P0" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A1Z6P0", "url": "https://www.uniprot.org/uniprotkb/A1Z6P0" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A1Z6P0", "url": "https://www.uniprot.org/uniprotkb/A1Z6P0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1Z6P0-1" }, { "uniprot_canonical_ac": "A1Z6U3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z6U3", "url": "https://www.uniprot.org/uniprotkb/A1Z6U3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 215, "chemical_mass": 23973.0, "gene_names": "Tsp42Ek;CG12841;Dm.Tsp42Ek;Dmel\\CG12841;Dmel_CG12841;Tsp42Ek", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A1Z6U3", "url": "https://www.uniprot.org/uniprotkb/A1Z6U3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A1Z6U3", "url": "https://www.uniprot.org/uniprotkb/A1Z6U3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1Z6U3-1" }, { "uniprot_canonical_ac": "A1Z6Y1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z6Y1", "url": "https://www.uniprot.org/uniprotkb/A1Z6Y1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 138, "chemical_mass": 15967.0, "gene_names": "Dmel\\CG11113;CG11113;Dmel\\CG11113;Dmel_CG11113", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A1Z6Y1", "url": "https://www.uniprot.org/uniprotkb/A1Z6Y1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1Z6Y1-1" }, { "uniprot_canonical_ac": "A1Z759-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z759", "url": "https://www.uniprot.org/uniprotkb/A1Z759" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 412, "chemical_mass": 46057.0, "gene_names": "CG12822-PA;CG12822-PA;CG12822;Dmel\\CG12822;Dmel_CG12822", "protein_name": "TsaA-like domain-containing protein", "disease": [], "biological_process": [ { "name": "tRNA methylation", "id": "GO:0030488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030488", "evidence": [ { "database": "UniProtKB", "id": "A1Z759", "url": "https://www.uniprot.org/uniprotkb/A1Z759" } ], "pmid": "" } ], "molecular_function": [ { "name": "tRNA (L-threonylcarbamoyladenosine(37)-C2) methyltransferase activity", "id": "GO:0089715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0089715", "evidence": [ { "database": "UniProtKB", "id": "A1Z759", "url": "https://www.uniprot.org/uniprotkb/A1Z759" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1Z759-1" }, { "uniprot_canonical_ac": "A1Z7D1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z7D1", "url": "https://www.uniprot.org/uniprotkb/A1Z7D1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 398, "chemical_mass": 44162.0, "gene_names": "CG2280;CG2280;CG30375;Dmel\\CG30375;Dmel_CG30375;SP80b;SP80", "protein_name": "", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A1Z7D1", "url": "https://www.uniprot.org/uniprotkb/A1Z7D1" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A1Z7D1", "url": "https://www.uniprot.org/uniprotkb/A1Z7D1" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A1Z7D1", "url": "https://www.uniprot.org/uniprotkb/A1Z7D1" } ], "pmid": "" }, { "name": "defense response to fungus", "id": "GO:0050832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050832", "evidence": [ { "database": "UniProtKB", "id": "A1Z7D1", "url": "https://www.uniprot.org/uniprotkb/A1Z7D1" } ], "pmid": "" }, { "name": "positive regulation of melanization defense response", "id": "GO:0035008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035008", "evidence": [ { "database": "UniProtKB", "id": "A1Z7D1", "url": "https://www.uniprot.org/uniprotkb/A1Z7D1" } ], "pmid": "" }, { "name": "Toll receptor ligand protein activation cascade", "id": "GO:0160032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160032", "evidence": [ { "database": "UniProtKB", "id": "A1Z7D1", "url": "https://www.uniprot.org/uniprotkb/A1Z7D1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1Z7D1-1" }, { "uniprot_canonical_ac": "A1Z7D6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z7D6", "url": "https://www.uniprot.org/uniprotkb/A1Z7D6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 469, "chemical_mass": 52502.0, "gene_names": "spaw;BcDNA:AT04457;CG2149;CG30365;Dmel\\CG30365;Dmel_CG30365;spaw", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1Z7D6-1" }, { "uniprot_canonical_ac": "A1Z7L8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 622, "chemical_mass": 69316.0, "gene_names": "babo;ATR-1;ATR-I;Atf1;Atr-1;Atr-I;Atr45A;AtrI;BABO;BaboA;Baboon;Babo;Bab;CG8224;Dmel\\CG8224;Gprk-3;Gprk3;STK-E;atr-I;babo;l(2)44Fd;l(2)k16912", "protein_name": "Receptor protein serine/threonine kinase babo", "disease": [ { "disease_id": "DOID:0050466", "name": "Loeys-Dietz syndrome", "description": "A syndrome that is characterized by increased risk of aortic aneurysm and dissection, elongated limbs, hypertelorism, bifid uvula and easy skin bruising due to mutations in TGFB3 that results in connective tissue defects.", "url": "https://disease-ontology.org/term/DOID:0050466", "evidence": [ { "id": "0050466", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050466" } ], "weight": 0.0 }, { "disease_id": "DOID:0070235", "name": "Loeys-Dietz syndrome 1", "description": "A Loeys-Dietz syndrome that has_material_basis_in heterozygous mutation in the TGFBR1 gene on chromosome 9q22.", "url": "https://disease-ontology.org/term/DOID:0070235", "evidence": [ { "id": "0070235", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070235" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:127", "name": "leiomyoma", "description": "A cell type benign neoplasm that is a benign tumor of smooth muscle cells.", "url": "https://disease-ontology.org/term/DOID:127", "evidence": [ { "id": "127", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:127" } ], "weight": 0.0 }, { "disease_id": "DOID:1790", "name": "malignant mesothelioma", "description": "A cell type cancer that has_material_basis_in mesothelial tissue that develops from the thin layer of tissue that covers many of the internal organs. Exposure to airborne asbestos particles increases one's risk of developing malignant mesothelioma.", "url": "https://disease-ontology.org/term/DOID:1790", "evidence": [ { "id": "1790", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1790" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:2256", "name": "osteochondrodysplasia", "description": "A bone development disease that results_in defective development of cartilage or bone.", "url": "https://disease-ontology.org/term/DOID:2256", "evidence": [ { "id": "2256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2256" } ], "weight": 0.0 }, { "disease_id": "DOID:3498", "name": "pancreatic ductal adenocarcinoma", "description": "A pancreatic adenocarcinoma that derives_from pancreatic duct cells.", "url": "https://disease-ontology.org/term/DOID:3498", "evidence": [ { "id": "3498", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3498" } ], "weight": 0.0 }, { "disease_id": "DOID:3883", "name": "Lynch syndrome", "description": "A syndrome that is characterized by an increased risk for colon cancer and cancers of the endometrium, ovary, stomach, small intestine, hepatobiliary tract, urinary tract, brain, and skin and has_material_basis_in mutation of mismatch repair genes that increases the risk of many types of cancers.", "url": "https://disease-ontology.org/term/DOID:3883", "evidence": [ { "id": "3883", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3883" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:418", "name": "systemic scleroderma", "description": "A scleroderma that is characterized by fibrosis (or hardening) of the skin and major organs, as well as vascular alterations, and autoantibodies.", "url": "https://disease-ontology.org/term/DOID:418", "evidence": [ { "id": "418", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:418" } ], "weight": 0.0 }, { "disease_id": "DOID:5409", "name": "lung small cell carcinoma", "description": "A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells and is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:5409", "evidence": [ { "id": "5409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5409" } ], "weight": 0.0 }, { "disease_id": "DOID:557", "name": "kidney disease", "description": "A urinary system disease that is located_in the kidney.", "url": "https://disease-ontology.org/term/DOID:557", "evidence": [ { "id": "557", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:557" } ], "weight": 0.0 }, { "disease_id": "DOID:5585", "name": "Ferguson-Smith tumor", "description": "", "url": "https://disease-ontology.org/term/DOID:5585", "evidence": [ { "id": "5585", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5585" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 }, { "disease_id": "DOID:8398", "name": "osteoarthritis", "description": "An arthritis that has_material_basis_in worn out cartilage located_in joint.", "url": "https://disease-ontology.org/term/DOID:8398", "evidence": [ { "id": "8398", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8398" } ], "weight": 0.0 }, { "disease_id": "DOID:8466", "name": "retinal degeneration", "description": "A retinal disease that is characterized by deterioration of the retina caused by the progressive and eventual death of the cells of the retina.", "url": "https://disease-ontology.org/term/DOID:8466", "evidence": [ { "id": "8466", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8466" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" } ], "pmid": "" }, { "name": "activin receptor activity, type I", "id": "GO:0016361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016361", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" } ], "pmid": "" }, { "name": "activin binding", "id": "GO:0048185", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048185", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" } ], "pmid": "" }, { "name": "activin receptor activity", "id": "GO:0017002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017002", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" } ], "pmid": "" }, { "name": "activin receptor complex", "id": "GO:0048179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048179", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" } ], "pmid": "" } ], "biological_process": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" } ], "pmid": "" }, { "name": "regulation of synapse structure or activity", "id": "GO:0050803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050803", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" } ], "pmid": "" }, { "name": "cellular response to growth factor stimulus", "id": "GO:0071363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071363", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" } ], "pmid": "" }, { "name": "negative regulation of autophagy", "id": "GO:0010507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010507", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" } ], "pmid": "" }, { "name": "response to UV", "id": "GO:0009411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009411", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" } ], "pmid": "" }, { "name": "response to stress", "id": "GO:0006950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006950", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" } ], "pmid": "" }, { "name": "activin receptor signaling pathway", "id": "GO:0032924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032924", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" } ], "pmid": "" }, { "name": "dendrite morphogenesis", "id": "GO:0048813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048813", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" } ], "pmid": "" }, { "name": "neuron development", "id": "GO:0048666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048666", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" } ], "pmid": "" }, { "name": "positive regulation of neuroblast proliferation", "id": "GO:0002052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002052", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" } ], "pmid": "" }, { "name": "determination of adult lifespan", "id": "GO:0008340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008340", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" } ], "pmid": "" }, { "name": "positive regulation of SMAD protein signal transduction", "id": "GO:0060391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060391", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" } ], "pmid": "" }, { "name": "eye-antennal disc morphogenesis", "id": "GO:0007455", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007455", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" } ], "pmid": "" }, { "name": "imaginal disc-derived wing morphogenesis", "id": "GO:0007476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007476", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" } ], "pmid": "" }, { "name": "mushroom body development", "id": "GO:0016319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016319", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" } ], "pmid": "" }, { "name": "regulation of imaginal disc-derived wing size", "id": "GO:0044719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044719", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" } ], "pmid": "" }, { "name": "R8 cell fate specification", "id": "GO:0045464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045464", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" } ], "pmid": "" }, { "name": "positive regulation of imaginal disc growth", "id": "GO:0045572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045572", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1Z7L8-1", "start_pos": "108", "end_pos": "108", "site_lbl": "Thr108", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 108, "start_aa": "Thr", "end_pos": 108, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr108", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A1Z7L8-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Asn32", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 32, "start_aa": "Asn", "end_pos": 32, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn32", "evidence": [ { "id": "A1Z7L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "A1Z7L8-1", "start_pos": "78", "end_pos": "78", "site_lbl": "Asn78", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 78, "start_aa": "Asn", "end_pos": 78, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn78", "evidence": [ { "id": "A1Z7L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "A1Z7L8-1", "start_pos": "85", "end_pos": "85", "site_lbl": "Asn85", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 85, "start_aa": "Asn", "end_pos": 85, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn85", "evidence": [ { "id": "A1Z7L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "A1Z7L8-1", "start_pos": "323", "end_pos": "323", "site_lbl": "Gln323", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "D", "comment": "Constitutively active kinase. Phosphorylates Smox/SMAD2 and Mad in the absence of activin or BMP signaling. Even in the absence of a type II receptor can weakly phosphorylate Smox/SMAD2.", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" }, { "database": "PubMed", "id": "10320478", "url": "https://glygen.org/publication/PubMed/10320478" }, { "database": "PubMed", "id": "22563507", "url": "https://glygen.org/publication/PubMed/22563507" } ] } ] }, { "uniprot_canonical_ac": "A1Z7L8-1", "start_pos": "351", "end_pos": "351", "site_lbl": "Lys351", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "Kinase inactive. Interacts with Smox/SMAD2 but does not phosphorylate it.", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L8", "url": "https://www.uniprot.org/uniprotkb/A1Z7L8" }, { "database": "PubMed", "id": "10320478", "url": "https://glygen.org/publication/PubMed/10320478" } ] } ] } ], "record_id": "A1Z7L8-1" }, { "uniprot_canonical_ac": "A1Z7R9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z7R9", "url": "https://www.uniprot.org/uniprotkb/A1Z7R9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 180, "chemical_mass": 19781.0, "gene_names": "Dmel\\CG42382;CG42382;CG8016;Dmel\\CG42382;Dmel_CG42382", "protein_name": "C3H1-type domain-containing protein", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A1Z7R9", "url": "https://www.uniprot.org/uniprotkb/A1Z7R9" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A1Z7R9", "url": "https://www.uniprot.org/uniprotkb/A1Z7R9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1Z7R9-1" }, { "uniprot_canonical_ac": "A1Z7U1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z7U1", "url": "https://www.uniprot.org/uniprotkb/A1Z7U1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 775, "chemical_mass": 85491.0, "gene_names": "Dmel\\CG13954;CG13954;Dmel\\CG13954;Dmel_CG13954", "protein_name": "Pneumococcal serine-rich repeat protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1Z7U1-1" }, { "uniprot_canonical_ac": "A1Z892-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z892", "url": "https://www.uniprot.org/uniprotkb/A1Z892" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 220, "chemical_mass": 24784.0, "gene_names": "Prx6b;1-cys peroxiredoxin DPx- 2540-1;BEST:LD11278;CG12405;DPx-2540-1;DPx2540;Dmel\\CG12405;Dmel_CG12405;Prx2540-1;Prx2540;Prx6b;dPRDX6-2;dPrx6a", "protein_name": "1-Cys peroxiredoxin", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A1Z892", "url": "https://www.uniprot.org/uniprotkb/A1Z892" } ], "pmid": "" } ], "biological_process": [ { "name": "cell redox homeostasis", "id": "GO:0045454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045454", "evidence": [ { "database": "UniProtKB", "id": "A1Z892", "url": "https://www.uniprot.org/uniprotkb/A1Z892" } ], "pmid": "" }, { "name": "hydrogen peroxide catabolic process", "id": "GO:0042744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042744", "evidence": [ { "database": "UniProtKB", "id": "A1Z892", "url": "https://www.uniprot.org/uniprotkb/A1Z892" } ], "pmid": "" } ], "molecular_function": [ { "name": "peroxiredoxin activity", "id": "GO:0051920", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051920", "evidence": [ { "database": "UniProtKB", "id": "A1Z892", "url": "https://www.uniprot.org/uniprotkb/A1Z892" } ], "pmid": "" }, { "name": "peroxidase activity", "id": "GO:0004601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004601", "evidence": [ { "database": "UniProtKB", "id": "A1Z892", "url": "https://www.uniprot.org/uniprotkb/A1Z892" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1Z892-1" }, { "uniprot_canonical_ac": "A1Z898-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z898", "url": "https://www.uniprot.org/uniprotkb/A1Z898" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 747, "chemical_mass": 83395.0, "gene_names": "Caf1-105;75;CAF p105;CAF-1 p105;CAF1-105;CAF1-p105;CAF1-p75/p105;CAF1-p75;CAF105/75;CAF1p105;CAF1p75;CAF1;CG12892;Caf-105;Caf1-105;Caf1-10;Caf1-p105;Caf1;Dmel\\CG12892;Dmel_CG12892;P105;caf1-105;dCAF-1-p105;dCAF1-p105;dCAF1-p75;p105/p75;p105;p75/p105;p75", "protein_name": "", "disease": [ { "disease_id": "DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050866", "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:3068", "name": "glioblastoma", "description": "A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.", "url": "https://disease-ontology.org/term/DOID:3068", "evidence": [ { "id": "3068", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3068" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 }, { "disease_id": "DOID:8923", "name": "skin melanoma", "description": "A skin cancer that has_material_basis_in melanocytes.", "url": "https://disease-ontology.org/term/DOID:8923", "evidence": [ { "id": "8923", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8923" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A1Z898", "url": "https://www.uniprot.org/uniprotkb/A1Z898" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A1Z898", "url": "https://www.uniprot.org/uniprotkb/A1Z898" } ], "pmid": "" }, { "name": "CAF-1 complex", "id": "GO:0033186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033186", "evidence": [ { "database": "UniProtKB", "id": "A1Z898", "url": "https://www.uniprot.org/uniprotkb/A1Z898" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A1Z898", "url": "https://www.uniprot.org/uniprotkb/A1Z898" } ], "pmid": "" }, { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "A1Z898", "url": "https://www.uniprot.org/uniprotkb/A1Z898" } ], "pmid": "" }, { "name": "DNA replication-dependent chromatin assembly", "id": "GO:0006335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006335", "evidence": [ { "database": "UniProtKB", "id": "A1Z898", "url": "https://www.uniprot.org/uniprotkb/A1Z898" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1Z898-1" }, { "uniprot_canonical_ac": "A1Z8G6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z8G6", "url": "https://www.uniprot.org/uniprotkb/A1Z8G6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 116, "chemical_mass": 12823.0, "gene_names": "Dmel\\CG13215;CG13215;Dmel\\CG13215;Dmel_CG13215", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1Z8G6-1" }, { "uniprot_canonical_ac": "A1Z8V9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z8V9", "url": "https://www.uniprot.org/uniprotkb/A1Z8V9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 629, "chemical_mass": 69730.0, "gene_names": "Dmel\\CG8850;CG8850;DmNAT4;Dmel\\CG8850;Dmel_CG8850", "protein_name": "Transporter", "disease": [ { "disease_id": "DOID:0050800", "name": "cerebral creatine deficiency syndrome 1", "description": "A cerebral creatine deficiency syndrome that is characterized by mental retardation, severe speech delay, behavioral abnormalities and seizures, has_material_basis_in mutation in the SLC6A8 gene on chromosome Xq28.", "url": "https://disease-ontology.org/term/DOID:0050800", "evidence": [ { "id": "0050800", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050800" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "neurotransmitter transmembrane transporter activity", "id": "GO:0005326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005326", "evidence": [ { "database": "UniProtKB", "id": "A1Z8V9", "url": "https://www.uniprot.org/uniprotkb/A1Z8V9" } ], "pmid": "" }, { "name": "L-amino acid transmembrane transporter activity", "id": "GO:0015179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015179", "evidence": [ { "database": "UniProtKB", "id": "A1Z8V9", "url": "https://www.uniprot.org/uniprotkb/A1Z8V9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A1Z8V9", "url": "https://www.uniprot.org/uniprotkb/A1Z8V9" } ], "pmid": "" }, { "name": "amino acid:sodium symporter activity", "id": "GO:0005283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005283", "evidence": [ { "database": "UniProtKB", "id": "A1Z8V9", "url": "https://www.uniprot.org/uniprotkb/A1Z8V9" } ], "pmid": "" }, { "name": "amino acid:monoatomic cation symporter activity", "id": "GO:0005416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005416", "evidence": [ { "database": "UniProtKB", "id": "A1Z8V9", "url": "https://www.uniprot.org/uniprotkb/A1Z8V9" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A1Z8V9", "url": "https://www.uniprot.org/uniprotkb/A1Z8V9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A1Z8V9", "url": "https://www.uniprot.org/uniprotkb/A1Z8V9" } ], "pmid": "" } ], "biological_process": [ { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "A1Z8V9", "url": "https://www.uniprot.org/uniprotkb/A1Z8V9" } ], "pmid": "" }, { "name": "amino acid transmembrane transport", "id": "GO:0003333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003333", "evidence": [ { "database": "UniProtKB", "id": "A1Z8V9", "url": "https://www.uniprot.org/uniprotkb/A1Z8V9" } ], "pmid": "" }, { "name": "neurotransmitter transport", "id": "GO:0006836", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006836", "evidence": [ { "database": "UniProtKB", "id": "A1Z8V9", "url": "https://www.uniprot.org/uniprotkb/A1Z8V9" } ], "pmid": "" }, { "name": "glycine import across plasma membrane", "id": "GO:1903804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903804", "evidence": [ { "database": "UniProtKB", "id": "A1Z8V9", "url": "https://www.uniprot.org/uniprotkb/A1Z8V9" } ], "pmid": "" }, { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "A1Z8V9", "url": "https://www.uniprot.org/uniprotkb/A1Z8V9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1Z8V9-1" }, { "uniprot_canonical_ac": "A1Z8X5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z8X5", "url": "https://www.uniprot.org/uniprotkb/A1Z8X5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 878, "chemical_mass": 99385.0, "gene_names": "CG30049-PA;CG30049-PA;CG30049;Dmel\\CG30049;Dmel_CG30049", "protein_name": "FXNA-like protease", "disease": [ { "disease_id": "DOID:784", "name": "chronic kidney disease", "description": "A kidney failure that is characterized by the gradual loss of kidney function, present for a minimum of 3 months. CKD is classified based on cause, glomerular filtration rate (GFR) category (G2-G5), and albuminuria category (A1-A3).", "url": "https://disease-ontology.org/term/DOID:784", "evidence": [ { "id": "784", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:784" } ], "weight": 0.0 } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A1Z8X5", "url": "https://www.uniprot.org/uniprotkb/A1Z8X5" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A1Z8X5", "url": "https://www.uniprot.org/uniprotkb/A1Z8X5" } ], "pmid": "" }, { "name": "metalloexopeptidase activity", "id": "GO:0008235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008235", "evidence": [ { "database": "UniProtKB", "id": "A1Z8X5", "url": "https://www.uniprot.org/uniprotkb/A1Z8X5" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A1Z8X5", "url": "https://www.uniprot.org/uniprotkb/A1Z8X5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1Z8X5-1" }, { "uniprot_canonical_ac": "A1Z935-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z935", "url": "https://www.uniprot.org/uniprotkb/A1Z935" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 660, "chemical_mass": 72897.0, "gene_names": "ZnT49B;CG8632;Dmel\\CG8632;Dmel_CG8632;ZNT49B;ZnT49B;cg8632;dZnT49B", "protein_name": "Proton-coupled zinc antiporter SLC30A9, mitochondrial", "disease": [], "molecular_function": [ { "name": "zinc ion transmembrane transporter activity", "id": "GO:0005385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005385", "evidence": [ { "database": "UniProtKB", "id": "A1Z935", "url": "https://www.uniprot.org/uniprotkb/A1Z935" } ], "pmid": "" }, { "name": "antiporter activity", "id": "GO:0015297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015297", "evidence": [ { "database": "UniProtKB", "id": "A1Z935", "url": "https://www.uniprot.org/uniprotkb/A1Z935" } ], "pmid": "" }, { "name": "monoatomic cation transmembrane transporter activity", "id": "GO:0008324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008324", "evidence": [ { "database": "UniProtKB", "id": "A1Z935", "url": "https://www.uniprot.org/uniprotkb/A1Z935" } ], "pmid": "" } ], "biological_process": [ { "name": "zinc ion transport", "id": "GO:0006829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006829", "evidence": [ { "database": "UniProtKB", "id": "A1Z935", "url": "https://www.uniprot.org/uniprotkb/A1Z935" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A1Z935", "url": "https://www.uniprot.org/uniprotkb/A1Z935" } ], "pmid": "" }, { "name": "intracellular zinc ion homeostasis", "id": "GO:0006882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006882", "evidence": [ { "database": "UniProtKB", "id": "A1Z935", "url": "https://www.uniprot.org/uniprotkb/A1Z935" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A1Z935", "url": "https://www.uniprot.org/uniprotkb/A1Z935" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A1Z935", "url": "https://www.uniprot.org/uniprotkb/A1Z935" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A1Z935", "url": "https://www.uniprot.org/uniprotkb/A1Z935" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "A1Z935", "url": "https://www.uniprot.org/uniprotkb/A1Z935" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1Z935-1" }, { "uniprot_canonical_ac": "A1Z9E3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z9E3", "url": "https://www.uniprot.org/uniprotkb/A1Z9E3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 489, "chemical_mass": 53992.0, "gene_names": "mEFTu1;CG6050;Dmel\\CG6050;Dmel_CG6050;EF-Tu1;EfTuM;TUFm;dTUFm;efTuM;eftu-M;l(3)L4569;mEFTu1;mtEF-Tu", "protein_name": "Elongation factor Tu", "disease": [ { "disease_id": "DOID:0070515", "name": "chromosome 16p11.2 deletion syndrome, 593-kb", "description": "A chromosomal deletion syndrome characterized by language delay and mild intellectual disability that has_material_basis_in partial deletion of a contiguous 593-kb region of chromosome 16p11.2 (chr16:29.5-30.1 Mb).", "url": "https://disease-ontology.org/term/DOID:0070515", "evidence": [ { "id": "0070515", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070515" } ], "weight": 0.0 }, { "disease_id": "DOID:0111494", "name": "combined oxidative phosphorylation deficiency 4", "description": "A combined oxidative phosphorylation deficiency that has_material_basis_in homozygous or compound heterozygous mutation in the TUFM gene on chromosome 16p11.2.", "url": "https://disease-ontology.org/term/DOID:0111494", "evidence": [ { "id": "0111494", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111494" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A1Z9E3", "url": "https://www.uniprot.org/uniprotkb/A1Z9E3" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A1Z9E3", "url": "https://www.uniprot.org/uniprotkb/A1Z9E3" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A1Z9E3", "url": "https://www.uniprot.org/uniprotkb/A1Z9E3" } ], "pmid": "" }, { "name": "translation elongation factor activity", "id": "GO:0003746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003746", "evidence": [ { "database": "UniProtKB", "id": "A1Z9E3", "url": "https://www.uniprot.org/uniprotkb/A1Z9E3" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A1Z9E3", "url": "https://www.uniprot.org/uniprotkb/A1Z9E3" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A1Z9E3", "url": "https://www.uniprot.org/uniprotkb/A1Z9E3" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial translational elongation", "id": "GO:0070125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070125", "evidence": [ { "database": "UniProtKB", "id": "A1Z9E3", "url": "https://www.uniprot.org/uniprotkb/A1Z9E3" } ], "pmid": "" }, { "name": "translational elongation", "id": "GO:0006414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006414", "evidence": [ { "database": "UniProtKB", "id": "A1Z9E3", "url": "https://www.uniprot.org/uniprotkb/A1Z9E3" } ], "pmid": "" }, { "name": "mitochondrial large ribosomal subunit assembly", "id": "GO:1902775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902775", "evidence": [ { "database": "UniProtKB", "id": "A1Z9E3", "url": "https://www.uniprot.org/uniprotkb/A1Z9E3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1Z9E3-1" }, { "uniprot_canonical_ac": "A1Z9G4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z9G4", "url": "https://www.uniprot.org/uniprotkb/A1Z9G4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 125, "chemical_mass": 14761.0, "gene_names": "Dmel\\CG12464;CG12464;Dmel\\CG12464;Dmel_CG12464", "protein_name": "", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A1Z9G4", "url": "https://www.uniprot.org/uniprotkb/A1Z9G4" } ], "pmid": "" }, { "name": "respiratory chain complex I", "id": "GO:0045271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045271", "evidence": [ { "database": "UniProtKB", "id": "A1Z9G4", "url": "https://www.uniprot.org/uniprotkb/A1Z9G4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1Z9G4-1" }, { "uniprot_canonical_ac": "A1Z9I0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z9I0", "url": "https://www.uniprot.org/uniprotkb/A1Z9I0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 439, "chemical_mass": 51635.0, "gene_names": "Dmel\\CG6357;CG6357;Dmel\\CG6357;Dmel_CG6357", "protein_name": "Cathepsin propeptide inhibitor domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1Z9I0-1" }, { "uniprot_canonical_ac": "A1Z9M5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z9M5", "url": "https://www.uniprot.org/uniprotkb/A1Z9M5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 4012, "chemical_mass": 460959.0, "gene_names": "Sdb;CG13017;CG30069;CG8381;Dmel\\CG30069;Dmel_CG30069;Sdb", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A1Z9M5", "url": "https://www.uniprot.org/uniprotkb/A1Z9M5" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A1Z9M5", "url": "https://www.uniprot.org/uniprotkb/A1Z9M5" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A1Z9M5", "url": "https://www.uniprot.org/uniprotkb/A1Z9M5" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A1Z9M5", "url": "https://www.uniprot.org/uniprotkb/A1Z9M5" } ], "pmid": "" }, { "name": "axonemal microtubule", "id": "GO:0005879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005879", "evidence": [ { "database": "UniProtKB", "id": "A1Z9M5", "url": "https://www.uniprot.org/uniprotkb/A1Z9M5" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A1Z9M5", "url": "https://www.uniprot.org/uniprotkb/A1Z9M5" } ], "pmid": "" } ], "biological_process": [ { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "A1Z9M5", "url": "https://www.uniprot.org/uniprotkb/A1Z9M5" } ], "pmid": "" }, { "name": "imaginal disc-derived wing morphogenesis", "id": "GO:0007476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007476", "evidence": [ { "database": "UniProtKB", "id": "A1Z9M5", "url": "https://www.uniprot.org/uniprotkb/A1Z9M5" } ], "pmid": "" }, { "name": "wing disc development", "id": "GO:0035220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035220", "evidence": [ { "database": "UniProtKB", "id": "A1Z9M5", "url": "https://www.uniprot.org/uniprotkb/A1Z9M5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1Z9M5-1", "start_pos": "19", "end_pos": "19", "site_lbl": "Thr19", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 19, "start_aa": "Thr", "end_pos": 19, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr19", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A1Z9M5", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A1Z9M5" } ] } ] }, { "uniprot_canonical_ac": "A1Z9M5-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Thr25", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 25, "start_aa": "Thr", "end_pos": 25, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr25", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A1Z9M5", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A1Z9M5" } ] } ] }, { "uniprot_canonical_ac": "A1Z9M5-1", "start_pos": "3289", "end_pos": "3289", "site_lbl": "Thr3289", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3289, "start_aa": "Thr", "end_pos": 3289, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3289", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A1Z9M5-1", "start_pos": "850", "end_pos": "850", "site_lbl": "Thr850", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 850, "start_aa": "Thr", "end_pos": 850, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr850", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A1Z9M5-1" }, { "uniprot_canonical_ac": "A1Z9Q4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z9Q4", "url": "https://www.uniprot.org/uniprotkb/A1Z9Q4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 185, "chemical_mass": 21002.0, "gene_names": "Obp50c;CG30072;DmelObp50c;Dmel\\CG30072;Dmel_CG30072;Obp50c", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A1Z9Q4", "url": "https://www.uniprot.org/uniprotkb/A1Z9Q4" } ], "pmid": "" } ], "biological_process": [ { "name": "sensory perception of chemical stimulus", "id": "GO:0007606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007606", "evidence": [ { "database": "UniProtKB", "id": "A1Z9Q4", "url": "https://www.uniprot.org/uniprotkb/A1Z9Q4" } ], "pmid": "" } ], "molecular_function": [ { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A1Z9Q4", "url": "https://www.uniprot.org/uniprotkb/A1Z9Q4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1Z9Q4-1" }, { "uniprot_canonical_ac": "A1Z9W8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z9W8", "url": "https://www.uniprot.org/uniprotkb/A1Z9W8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 54, "chemical_mass": 5319.0, "gene_names": "NEST:bs26d12;CG12853;Dmel\\CG12853;Dmel_CG12853;NEST:bs26d12;bs26d12.y1", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1Z9W8-1" }, { "uniprot_canonical_ac": "A1ZA28-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZA28", "url": "https://www.uniprot.org/uniprotkb/A1ZA28" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 143, "chemical_mass": 16290.0, "gene_names": "Dmel\\CG8204;BcDNA:AT23078;CG8204;Dmel\\CG8204;Dmel_CG8204", "protein_name": "HIT-type domain-containing protein", "disease": [ { "disease_id": "DOID:0080539", "name": "PEHO syndrome", "description": "A brain disease that is characterized by extreme cerebellar atrophy due to almost total granule neuron loss.", "url": "https://disease-ontology.org/term/DOID:0080539", "evidence": [ { "id": "0080539", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080539" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A1ZA28", "url": "https://www.uniprot.org/uniprotkb/A1ZA28" } ], "pmid": "" }, { "name": "pre-snoRNP complex", "id": "GO:0070761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070761", "evidence": [ { "database": "UniProtKB", "id": "A1ZA28", "url": "https://www.uniprot.org/uniprotkb/A1ZA28" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A1ZA28", "url": "https://www.uniprot.org/uniprotkb/A1ZA28" } ], "pmid": "" } ], "biological_process": [ { "name": "box C/D snoRNP assembly", "id": "GO:0000492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000492", "evidence": [ { "database": "UniProtKB", "id": "A1ZA28", "url": "https://www.uniprot.org/uniprotkb/A1ZA28" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000463", "evidence": [ { "database": "UniProtKB", "id": "A1ZA28", "url": "https://www.uniprot.org/uniprotkb/A1ZA28" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1ZA28-1" }, { "uniprot_canonical_ac": "A1ZA39-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZA39", "url": "https://www.uniprot.org/uniprotkb/A1ZA39" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 277, "chemical_mass": 30916.0, "gene_names": "Dmel\\CG30087;CG30087;CG8215;CR30087;Dmel\\CG30087;Dmel_CG30087;SP218;SP41", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A1ZA39", "url": "https://www.uniprot.org/uniprotkb/A1ZA39" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A1ZA39", "url": "https://www.uniprot.org/uniprotkb/A1ZA39" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A1ZA39", "url": "https://www.uniprot.org/uniprotkb/A1ZA39" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A1ZA39", "url": "https://www.uniprot.org/uniprotkb/A1ZA39" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A1ZA39", "url": "https://www.uniprot.org/uniprotkb/A1ZA39" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "A1ZA39", "url": "https://www.uniprot.org/uniprotkb/A1ZA39" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1ZA39-1" }, { "uniprot_canonical_ac": "A1ZA42-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZA42", "url": "https://www.uniprot.org/uniprotkb/A1ZA42" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 300, "chemical_mass": 34667.0, "gene_names": "CG30086;CG30086;CG33462;CG8215;Dmel\\CG33462;Dmel_CG33462;SP240;SP41", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A1ZA42", "url": "https://www.uniprot.org/uniprotkb/A1ZA42" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A1ZA42", "url": "https://www.uniprot.org/uniprotkb/A1ZA42" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A1ZA42", "url": "https://www.uniprot.org/uniprotkb/A1ZA42" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A1ZA42", "url": "https://www.uniprot.org/uniprotkb/A1ZA42" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A1ZA42", "url": "https://www.uniprot.org/uniprotkb/A1ZA42" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A1ZA42", "url": "https://www.uniprot.org/uniprotkb/A1ZA42" } ], "pmid": "" }, { "name": "mating", "id": "GO:0007618", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007618", "evidence": [ { "database": "UniProtKB", "id": "A1ZA42", "url": "https://www.uniprot.org/uniprotkb/A1ZA42" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1ZA42-1" }, { "uniprot_canonical_ac": "A1ZA83-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZA83", "url": "https://www.uniprot.org/uniprotkb/A1ZA83" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 245, "chemical_mass": 27795.0, "gene_names": "EMC7;CG8397;Dmel\\CG8397;Dmel_CG8397;EMC7;emc7", "protein_name": "", "disease": [], "cellular_component": [ { "name": "EMC complex", "id": "GO:0072546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072546", "evidence": [ { "database": "UniProtKB", "id": "A1ZA83", "url": "https://www.uniprot.org/uniprotkb/A1ZA83" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A1ZA83", "url": "https://www.uniprot.org/uniprotkb/A1ZA83" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A1ZA83", "url": "https://www.uniprot.org/uniprotkb/A1ZA83" } ], "pmid": "" } ], "molecular_function": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A1ZA83", "url": "https://www.uniprot.org/uniprotkb/A1ZA83" } ], "pmid": "" } ], "biological_process": [ { "name": "tail-anchored membrane protein insertion into ER membrane", "id": "GO:0071816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071816", "evidence": [ { "database": "UniProtKB", "id": "A1ZA83", "url": "https://www.uniprot.org/uniprotkb/A1ZA83" } ], "pmid": "" }, { "name": "protein insertion into ER membrane by stop-transfer membrane-anchor sequence", "id": "GO:0045050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045050", "evidence": [ { "database": "UniProtKB", "id": "A1ZA83", "url": "https://www.uniprot.org/uniprotkb/A1ZA83" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1ZA83-1" }, { "uniprot_canonical_ac": "A1ZA87-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZA87", "url": "https://www.uniprot.org/uniprotkb/A1ZA87" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1361, "chemical_mass": 150299.0, "gene_names": "SP2353;BcDNA:GH12319;CG8403;CT18665;Dmel\\CG8403;Dmel_CG8403;Hspg2;SP2353", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A1ZA87", "url": "https://www.uniprot.org/uniprotkb/A1ZA87" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A1ZA87", "url": "https://www.uniprot.org/uniprotkb/A1ZA87" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A1ZA87", "url": "https://www.uniprot.org/uniprotkb/A1ZA87" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "A1ZA87", "url": "https://www.uniprot.org/uniprotkb/A1ZA87" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A1ZA87", "url": "https://www.uniprot.org/uniprotkb/A1ZA87" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A1ZA87", "url": "https://www.uniprot.org/uniprotkb/A1ZA87" } ], "pmid": "" }, { "name": "muscle cell cellular homeostasis", "id": "GO:0046716", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046716", "evidence": [ { "database": "UniProtKB", "id": "A1ZA87", "url": "https://www.uniprot.org/uniprotkb/A1ZA87" } ], "pmid": "" }, { "name": "defense response to Gram-negative bacterium", "id": "GO:0050829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050829", "evidence": [ { "database": "UniProtKB", "id": "A1ZA87", "url": "https://www.uniprot.org/uniprotkb/A1ZA87" } ], "pmid": "" }, { "name": "negative regulation of innate immune response", "id": "GO:0045824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045824", "evidence": [ { "database": "UniProtKB", "id": "A1ZA87", "url": "https://www.uniprot.org/uniprotkb/A1ZA87" } ], "pmid": "" }, { "name": "rhabdomere development", "id": "GO:0042052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042052", "evidence": [ { "database": "UniProtKB", "id": "A1ZA87", "url": "https://www.uniprot.org/uniprotkb/A1ZA87" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A1ZA87", "url": "https://www.uniprot.org/uniprotkb/A1ZA87" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1ZA87-1", "start_pos": "230", "end_pos": "230", "site_lbl": "Thr230", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 230, "start_aa": "Thr", "end_pos": 230, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr230", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A1ZA87-1" }, { "uniprot_canonical_ac": "A1ZAG1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZAG1", "url": "https://www.uniprot.org/uniprotkb/A1ZAG1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 233, "chemical_mass": 27167.0, "gene_names": "jtb;CG4398;Dmel\\CG4398;Dmel_CG4398;jtb", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1ZAG1-1" }, { "uniprot_canonical_ac": "A1ZAJ7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZAJ7", "url": "https://www.uniprot.org/uniprotkb/A1ZAJ7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 363, "chemical_mass": 42747.0, "gene_names": "Dmel\\CG15615;CG15615;Dmel\\CG15615;Dmel_CG15615", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1ZAJ7-1" }, { "uniprot_canonical_ac": "A1ZAL6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZAL6", "url": "https://www.uniprot.org/uniprotkb/A1ZAL6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 469, "chemical_mass": 52761.0, "gene_names": "Dmel\\CG15614;CG15614;Dmel\\CG15614;Dmel_CG15614", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A1ZAL6", "url": "https://www.uniprot.org/uniprotkb/A1ZAL6" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A1ZAL6", "url": "https://www.uniprot.org/uniprotkb/A1ZAL6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1ZAL6-1" }, { "uniprot_canonical_ac": "A1ZAT2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZAT2", "url": "https://www.uniprot.org/uniprotkb/A1ZAT2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 523, "chemical_mass": 57708.0, "gene_names": "Dmel\\CG10764;CG10764;Dmel\\CG10764;Dmel_CG10764;FBgn0034221;GENE 2;SP77;anon-54Ba;gene 2", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A1ZAT2", "url": "https://www.uniprot.org/uniprotkb/A1ZAT2" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A1ZAT2", "url": "https://www.uniprot.org/uniprotkb/A1ZAT2" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A1ZAT2", "url": "https://www.uniprot.org/uniprotkb/A1ZAT2" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A1ZAT2", "url": "https://www.uniprot.org/uniprotkb/A1ZAT2" } ], "pmid": "" }, { "name": "negative regulation of hemocyte proliferation", "id": "GO:0035207", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035207", "evidence": [ { "database": "UniProtKB", "id": "A1ZAT2", "url": "https://www.uniprot.org/uniprotkb/A1ZAT2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1ZAT2-1" }, { "uniprot_canonical_ac": "A1ZAT5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZAT5", "url": "https://www.uniprot.org/uniprotkb/A1ZAT5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 816, "chemical_mass": 89849.0, "gene_names": "Tes;CG6522;Dmel\\CG6522;Dmel_CG6522;Tes;dTES", "protein_name": "", "disease": [ { "disease_id": "DOID:0080144", "name": "childhood acute lymphocytic leukemia", "description": "An acute lymphocytic leukemia occurring during childhood.", "url": "https://disease-ontology.org/term/DOID:0080144", "evidence": [ { "id": "0080144", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080144" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:2871", "name": "endometrial carcinoma", "description": "A endometrial cancer that is located_in the tissue lining the uterus.", "url": "https://disease-ontology.org/term/DOID:2871", "evidence": [ { "id": "2871", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2871" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:4248", "name": "coronary stenosis", "description": "", "url": "https://disease-ontology.org/term/DOID:4248", "evidence": [ { "id": "4248", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4248" } ], "weight": 0.0 }, { "disease_id": "DOID:5165", "name": "uterine corpus sarcoma", "description": "An uterine corpus cancer that is located_in the muscles of the uterus or located_in other tissues that support the uterus.", "url": "https://disease-ontology.org/term/DOID:5165", "evidence": [ { "id": "5165", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5165" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1ZAT5", "url": "https://www.uniprot.org/uniprotkb/A1ZAT5" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A1ZAT5", "url": "https://www.uniprot.org/uniprotkb/A1ZAT5" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A1ZAT5", "url": "https://www.uniprot.org/uniprotkb/A1ZAT5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1ZAT5-1", "start_pos": "569", "end_pos": "569", "site_lbl": "Thr569", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 569, "start_aa": "Thr", "end_pos": 569, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr569", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A1ZAT5-1" }, { "uniprot_canonical_ac": "A1ZAW9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZAW9", "url": "https://www.uniprot.org/uniprotkb/A1ZAW9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 84, "chemical_mass": 9934.0, "gene_names": "Oxp;CG18186;Dmel\\CG18186;Dmel_CG18186;OXP;Oxp", "protein_name": "", "disease": [], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW9", "url": "https://www.uniprot.org/uniprotkb/A1ZAW9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW9", "url": "https://www.uniprot.org/uniprotkb/A1ZAW9" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW9", "url": "https://www.uniprot.org/uniprotkb/A1ZAW9" } ], "pmid": "" }, { "name": "pericentric heterochromatin", "id": "GO:0005721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005721", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW9", "url": "https://www.uniprot.org/uniprotkb/A1ZAW9" } ], "pmid": "" } ], "biological_process": [ { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW9", "url": "https://www.uniprot.org/uniprotkb/A1ZAW9" } ], "pmid": "" }, { "name": "chromosome organization", "id": "GO:0051276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051276", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW9", "url": "https://www.uniprot.org/uniprotkb/A1ZAW9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1ZAW9-1" }, { "uniprot_canonical_ac": "A1ZAY5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZAY5", "url": "https://www.uniprot.org/uniprotkb/A1ZAY5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 283, "chemical_mass": 33184.0, "gene_names": "Dmel\\CG34195;CG34195;CG4989;Dmel\\CG34195;Dmel_CG34195;METTL6", "protein_name": "tRNA N(3)-methylcytidine methyltransferase", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A1ZAY5", "url": "https://www.uniprot.org/uniprotkb/A1ZAY5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1ZAY5", "url": "https://www.uniprot.org/uniprotkb/A1ZAY5" } ], "pmid": "" } ], "biological_process": [ { "name": "tRNA methylation", "id": "GO:0030488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030488", "evidence": [ { "database": "UniProtKB", "id": "A1ZAY5", "url": "https://www.uniprot.org/uniprotkb/A1ZAY5" } ], "pmid": "" } ], "molecular_function": [ { "name": "tRNA (cytidine) methyltransferase activity", "id": "GO:0016427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016427", "evidence": [ { "database": "UniProtKB", "id": "A1ZAY5", "url": "https://www.uniprot.org/uniprotkb/A1ZAY5" } ], "pmid": "" }, { "name": "tRNA (cytidine-3-)-methyltransferase activity", "id": "GO:0052735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052735", "evidence": [ { "database": "UniProtKB", "id": "A1ZAY5", "url": "https://www.uniprot.org/uniprotkb/A1ZAY5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1ZAY5-1" }, { "uniprot_canonical_ac": "A1ZB12-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZB12", "url": "https://www.uniprot.org/uniprotkb/A1ZB12" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 199, "chemical_mass": 23543.0, "gene_names": "Dmel\\CG14492;CG14492;Dmel\\CG14492;Dmel_CG14492", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1ZB12-1" }, { "uniprot_canonical_ac": "A1ZB49-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZB49", "url": "https://www.uniprot.org/uniprotkb/A1ZB49" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 115, "chemical_mass": 13121.0, "gene_names": "Dmel\\CG30114;CG30114;Dmel\\CG30114;Dmel_CG30114;FBgn0050114", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1ZB49-1" }, { "uniprot_canonical_ac": "A1ZB56-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZB56", "url": "https://www.uniprot.org/uniprotkb/A1ZB56" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 182, "chemical_mass": 20860.0, "gene_names": "Dmel\\CG18538;CG18538;Dmel\\CG18538;Dmel_CG18538", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1ZB56-1" }, { "uniprot_canonical_ac": "A1ZB72-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZB72", "url": "https://www.uniprot.org/uniprotkb/A1ZB72" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 223, "chemical_mass": 25510.0, "gene_names": "GstE7;CG17531;DmGSTE7;Dmel\\CG17531;Dmel_CG17531;E7;GST-E7;GSTE7;GstE7;gstE7;gste7", "protein_name": "", "disease": [], "molecular_function": [ { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "A1ZB72", "url": "https://www.uniprot.org/uniprotkb/A1ZB72" } ], "pmid": "" }, { "name": "glutathione peroxidase activity", "id": "GO:0004602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004602", "evidence": [ { "database": "UniProtKB", "id": "A1ZB72", "url": "https://www.uniprot.org/uniprotkb/A1ZB72" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1ZB72", "url": "https://www.uniprot.org/uniprotkb/A1ZB72" } ], "pmid": "" } ], "biological_process": [ { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "A1ZB72", "url": "https://www.uniprot.org/uniprotkb/A1ZB72" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1ZB72-1" }, { "uniprot_canonical_ac": "A1ZBD2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZBD2", "url": "https://www.uniprot.org/uniprotkb/A1ZBD2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 262, "chemical_mass": 30958.0, "gene_names": "Dmel\\CG17821;CG17821;Dmel\\CG17821;Dmel_CG17821", "protein_name": "Elongation of very long chain fatty acids protein", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A1ZBD2", "url": "https://www.uniprot.org/uniprotkb/A1ZBD2" } ], "pmid": "" } ], "biological_process": [ { "name": "sphingolipid biosynthetic process", "id": "GO:0030148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030148", "evidence": [ { "database": "UniProtKB", "id": "A1ZBD2", "url": "https://www.uniprot.org/uniprotkb/A1ZBD2" } ], "pmid": "" }, { "name": "fatty acid elongation", "id": "GO:0030497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030497", "evidence": [ { "database": "UniProtKB", "id": "A1ZBD2", "url": "https://www.uniprot.org/uniprotkb/A1ZBD2" } ], "pmid": "" }, { "name": "fatty acid elongation, monounsaturated fatty acid", "id": "GO:0034625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034625", "evidence": [ { "database": "UniProtKB", "id": "A1ZBD2", "url": "https://www.uniprot.org/uniprotkb/A1ZBD2" } ], "pmid": "" }, { "name": "fatty acid elongation, polyunsaturated fatty acid", "id": "GO:0034626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034626", "evidence": [ { "database": "UniProtKB", "id": "A1ZBD2", "url": "https://www.uniprot.org/uniprotkb/A1ZBD2" } ], "pmid": "" }, { "name": "fatty acid elongation, saturated fatty acid", "id": "GO:0019367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019367", "evidence": [ { "database": "UniProtKB", "id": "A1ZBD2", "url": "https://www.uniprot.org/uniprotkb/A1ZBD2" } ], "pmid": "" }, { "name": "very long-chain fatty acid biosynthetic process", "id": "GO:0042761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042761", "evidence": [ { "database": "UniProtKB", "id": "A1ZBD2", "url": "https://www.uniprot.org/uniprotkb/A1ZBD2" } ], "pmid": "" } ], "molecular_function": [ { "name": "fatty acid elongase activity", "id": "GO:0009922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009922", "evidence": [ { "database": "UniProtKB", "id": "A1ZBD2", "url": "https://www.uniprot.org/uniprotkb/A1ZBD2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1ZBD2-1" }, { "uniprot_canonical_ac": "A1ZBN5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZBN5", "url": "https://www.uniprot.org/uniprotkb/A1ZBN5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 867, "chemical_mass": 101230.0, "gene_names": "TTLL6A;CG16716;DmCG16716;Dmel\\CG16716;Dmel_CG16716;TTLL6A;TTLL6;anon-WO0140519.27", "protein_name": "", "disease": [], "molecular_function": [ { "name": "tubulin-glutamic acid ligase activity", "id": "GO:0070740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070740", "evidence": [ { "database": "UniProtKB", "id": "A1ZBN5", "url": "https://www.uniprot.org/uniprotkb/A1ZBN5" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A1ZBN5", "url": "https://www.uniprot.org/uniprotkb/A1ZBN5" } ], "pmid": "" }, { "name": "tubulin binding", "id": "GO:0015631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015631", "evidence": [ { "database": "UniProtKB", "id": "A1ZBN5", "url": "https://www.uniprot.org/uniprotkb/A1ZBN5" } ], "pmid": "" } ], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A1ZBN5", "url": "https://www.uniprot.org/uniprotkb/A1ZBN5" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A1ZBN5", "url": "https://www.uniprot.org/uniprotkb/A1ZBN5" } ], "pmid": "" } ], "biological_process": [ { "name": "microtubule bundle formation", "id": "GO:0001578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001578", "evidence": [ { "database": "UniProtKB", "id": "A1ZBN5", "url": "https://www.uniprot.org/uniprotkb/A1ZBN5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1ZBN5-1", "start_pos": "321", "end_pos": "321", "site_lbl": "Thr321", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 321, "start_aa": "Thr", "end_pos": 321, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr321", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A1ZBN5-1" }, { "uniprot_canonical_ac": "A1ZBS3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZBS3", "url": "https://www.uniprot.org/uniprotkb/A1ZBS3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1626, "chemical_mass": 185311.0, "gene_names": "Dmel\\CG8908;CG8908;DmCG8908;Dmel\\CG8908;Dmel_CG8908", "protein_name": "ABC transporter domain-containing protein", "disease": [ { "disease_id": "DOID:11161", "name": "neonatal respiratory failure", "description": "A respiratory failure that is characterized by inadequate gas exchange by the respiratory system in neonates.", "url": "https://disease-ontology.org/term/DOID:11161", "evidence": [ { "id": "11161", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11161" } ], "weight": 0.0 }, { "disease_id": "DOID:11162", "name": "respiratory failure", "description": "A lung disease characterized by inadequate gas exchange by the respiratory system.", "url": "https://disease-ontology.org/term/DOID:11162", "evidence": [ { "id": "11162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11162" } ], "weight": 0.0 }, { "disease_id": "DOID:12120", "name": "pulmonary alveolar proteinosis", "description": "A lung disease that is characterized by abnormal accumulation of surfactant occurs within the alveoli, interfering with gas exchange.", "url": "https://disease-ontology.org/term/DOID:12120", "evidence": [ { "id": "12120", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12120" } ], "weight": 0.0 }, { "disease_id": "DOID:12716", "name": "newborn respiratory distress syndrome", "description": "A respiratory failure that is characterized by deficiency of the surfactant coating the inner surface of the lungs, by failure of the lungs to expand and contract properly during breathing with resulting collapse, and by the accumulation of a protein-containing film lining the alveoli and their ducts.", "url": "https://disease-ontology.org/term/DOID:12716", "evidence": [ { "id": "12716", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12716" } ], "weight": 0.0 }, { "disease_id": "DOID:3082", "name": "interstitial lung disease", "description": "A lung disease that is characterized by inflammation and altered lung interstitium compromising pulmonary function and often has_symptom shortness of breath, dyspnea, and/or cough.", "url": "https://disease-ontology.org/term/DOID:3082", "evidence": [ { "id": "3082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3082" } ], "weight": 0.0 }, { "disease_id": "DOID:850", "name": "lung disease", "description": "A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide.", "url": "https://disease-ontology.org/term/DOID:850", "evidence": [ { "id": "850", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:850" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "lipid transporter activity", "id": "GO:0005319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005319", "evidence": [ { "database": "UniProtKB", "id": "A1ZBS3", "url": "https://www.uniprot.org/uniprotkb/A1ZBS3" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A1ZBS3", "url": "https://www.uniprot.org/uniprotkb/A1ZBS3" } ], "pmid": "" }, { "name": "ATPase-coupled transmembrane transporter activity", "id": "GO:0042626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042626", "evidence": [ { "database": "UniProtKB", "id": "A1ZBS3", "url": "https://www.uniprot.org/uniprotkb/A1ZBS3" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A1ZBS3", "url": "https://www.uniprot.org/uniprotkb/A1ZBS3" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "A1ZBS3", "url": "https://www.uniprot.org/uniprotkb/A1ZBS3" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "A1ZBS3", "url": "https://www.uniprot.org/uniprotkb/A1ZBS3" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A1ZBS3", "url": "https://www.uniprot.org/uniprotkb/A1ZBS3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1ZBS3-1", "start_pos": "144", "end_pos": "144", "site_lbl": "Thr144", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 144, "start_aa": "Thr", "end_pos": 144, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr144", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A1ZBS3-1" }, { "uniprot_canonical_ac": "A1ZBT2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZBT2", "url": "https://www.uniprot.org/uniprotkb/A1ZBT2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 587, "chemical_mass": 65865.0, "gene_names": "Dmel\\CG13868;CG13868;Dmel_CG13868;anon-WO0153538.60", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1ZBT2-1" }, { "uniprot_canonical_ac": "A1ZBU8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZBU8", "url": "https://www.uniprot.org/uniprotkb/A1ZBU8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 245, "chemical_mass": 26230.0, "gene_names": "Bbd;Bbd;CG18067;CT40493;Dmel\\CG18067;Dmel_CG18067;bbd", "protein_name": "", "disease": [], "biological_process": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "A1ZBU8", "url": "https://www.uniprot.org/uniprotkb/A1ZBU8" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A1ZBU8", "url": "https://www.uniprot.org/uniprotkb/A1ZBU8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1ZBU8-1" }, { "uniprot_canonical_ac": "A1ZBX9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZBX9", "url": "https://www.uniprot.org/uniprotkb/A1ZBX9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 149, "chemical_mass": 17627.0, "gene_names": "Dmel\\CG13437;CG13437;Dmel\\CG13437;Dmel_CG13437", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1ZBX9-1" }, { "uniprot_canonical_ac": "A1ZBY4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZBY4", "url": "https://www.uniprot.org/uniprotkb/A1ZBY4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 425, "chemical_mass": 47498.0, "gene_names": "Dmel\\CG13442;CG13442;Dmel\\CG13442;Dmel_CG13442", "protein_name": "RING-CH-type domain-containing protein", "disease": [], "cellular_component": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A1ZBY4", "url": "https://www.uniprot.org/uniprotkb/A1ZBY4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A1ZBY4", "url": "https://www.uniprot.org/uniprotkb/A1ZBY4" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A1ZBY4", "url": "https://www.uniprot.org/uniprotkb/A1ZBY4" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A1ZBY4", "url": "https://www.uniprot.org/uniprotkb/A1ZBY4" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A1ZBY4", "url": "https://www.uniprot.org/uniprotkb/A1ZBY4" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A1ZBY4", "url": "https://www.uniprot.org/uniprotkb/A1ZBY4" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A1ZBY4", "url": "https://www.uniprot.org/uniprotkb/A1ZBY4" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A1ZBY4", "url": "https://www.uniprot.org/uniprotkb/A1ZBY4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1ZBY4-1" }, { "uniprot_canonical_ac": "A1ZBY5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZBY5", "url": "https://www.uniprot.org/uniprotkb/A1ZBY5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 436, "chemical_mass": 48279.0, "gene_names": "Dmel\\CG13443;CG13443;Dmel\\CG13443;Dmel_CG13443", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A1ZBY5-1" }, { "uniprot_canonical_ac": "A8DY43-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8DY43", "url": "https://www.uniprot.org/uniprotkb/A8DY43" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1420, "chemical_mass": 156703.0, "gene_names": "Dmel\\CG43795;CG13552;CG13553;CG13556;CG18678;CG18679;CG34372;CG43795;CG5357;Dmel\\CG43795;Dmel_CG43795", "protein_name": "G-protein coupled receptors family 3 profile domain-containing protein", "disease": [ { "disease_id": "DOID:0110869", "name": "congenital stationary night blindness 1E", "description": "A congenital stationary night blindness characterized by autosomal recessive inheritance that has_material_basis_in homozygous or compound heterozygous mutation in the GPR179 gene on chromosome 17q12.", "url": "https://disease-ontology.org/term/DOID:0110869", "evidence": [ { "id": "0110869", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110869" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A8DY43", "url": "https://www.uniprot.org/uniprotkb/A8DY43" } ], "pmid": "" } ], "cellular_component": [ { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A8DY43", "url": "https://www.uniprot.org/uniprotkb/A8DY43" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A8DY43", "url": "https://www.uniprot.org/uniprotkb/A8DY43" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A8DY43-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Thr112", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 112, "start_aa": "Thr", "end_pos": 112, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr112", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A8DY43-1", "start_pos": "1157", "end_pos": "1157", "site_lbl": "Thr1157", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1157, "start_aa": "Thr", "end_pos": 1157, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1157", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "A8DY43-1" }, { "uniprot_canonical_ac": "A8DY51-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8DY51", "url": "https://www.uniprot.org/uniprotkb/A8DY51" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 97, "chemical_mass": 10868.0, "gene_names": "Dmel\\CG12828;CG12828;Dmel\\CG12828;Dmel_CG12828", "protein_name": "Seminal fluid protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8DY51-1" }, { "uniprot_canonical_ac": "A8DYB9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8DYB9", "url": "https://www.uniprot.org/uniprotkb/A8DYB9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 536, "chemical_mass": 57583.0, "gene_names": "s-cup;CG13152;CG13153;CG30044;Dmel\\CG30044;Dmel_CG30044;s-cup", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8DYB9-1" }, { "uniprot_canonical_ac": "A8DYD4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8DYD4", "url": "https://www.uniprot.org/uniprotkb/A8DYD4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 224, "chemical_mass": 25756.0, "gene_names": "Dmel\\CG34184;CG34184;Dmel\\CG34184;Dmel_CG34184", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A8DYD4-1", "start_pos": "104", "end_pos": "104", "site_lbl": "Thr104", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 104, "start_aa": "Thr", "end_pos": 104, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr104", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A8DYD4", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A8DYD4" } ] } ] } ], "record_id": "A8DYD4-1" }, { "uniprot_canonical_ac": "A8DYD8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8DYD8", "url": "https://www.uniprot.org/uniprotkb/A8DYD8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 126, "chemical_mass": 14099.0, "gene_names": "Dmel\\CG34185;CG34185;Dmel\\CG34185;Dmel_CG34185", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8DYD8-1" }, { "uniprot_canonical_ac": "A8DYG0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8DYG0", "url": "https://www.uniprot.org/uniprotkb/A8DYG0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 257, "chemical_mass": 27378.0, "gene_names": "SP118;CG34458;CG5197;Dmel\\CG34458;Dmel_CG34458;SP118", "protein_name": "Peptidase S1 domain-containing protein", "disease": [ { "disease_id": "DOID:4989", "name": "pancreatitis", "description": "A pancreas disease that is characterized by inflammation of the pancreas.", "url": "https://disease-ontology.org/term/DOID:4989", "evidence": [ { "id": "4989", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4989" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A8DYG0", "url": "https://www.uniprot.org/uniprotkb/A8DYG0" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A8DYG0", "url": "https://www.uniprot.org/uniprotkb/A8DYG0" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A8DYG0", "url": "https://www.uniprot.org/uniprotkb/A8DYG0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8DYG0-1" }, { "uniprot_canonical_ac": "A8DYL6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8DYL6", "url": "https://www.uniprot.org/uniprotkb/A8DYL6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 101, "chemical_mass": 12184.0, "gene_names": "Dmel\\CG34207;CG34207;Dmel\\CG34207;Dmel_CG34207", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8DYL6-1" }, { "uniprot_canonical_ac": "A8DYV0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8DYV0", "url": "https://www.uniprot.org/uniprotkb/A8DYV0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 107, "chemical_mass": 11814.0, "gene_names": "Dmel\\CG34177;CG12677;CG34177;Dmel\\CG34177;Dmel_CG34177", "protein_name": "Single domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A8DYV0", "url": "https://www.uniprot.org/uniprotkb/A8DYV0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8DYV0-1" }, { "uniprot_canonical_ac": "A8DYZ4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8DYZ4", "url": "https://www.uniprot.org/uniprotkb/A8DYZ4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 535, "chemical_mass": 61759.0, "gene_names": "Dmel\\CG34162;CG34162;Dmel\\CG34162;Dmel_CG34162", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8DYZ4-1" }, { "uniprot_canonical_ac": "A8DZ10-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8DZ10", "url": "https://www.uniprot.org/uniprotkb/A8DZ10" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 281, "chemical_mass": 32811.0, "gene_names": "Snrnp25;CG34313;CG4826;Dmel\\CG34313;Dmel_CG34313", "protein_name": "SNRNP25 ubiquitin-like domain-containing protein", "disease": [], "cellular_component": [ { "name": "U11/U12 snRNP", "id": "GO:0034693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034693", "evidence": [ { "database": "UniProtKB", "id": "A8DZ10", "url": "https://www.uniprot.org/uniprotkb/A8DZ10" } ], "pmid": "" }, { "name": "U12-type spliceosomal complex", "id": "GO:0005689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005689", "evidence": [ { "database": "UniProtKB", "id": "A8DZ10", "url": "https://www.uniprot.org/uniprotkb/A8DZ10" } ], "pmid": "" } ], "biological_process": [ { "name": "alternative mRNA splicing, via spliceosome", "id": "GO:0000380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000380", "evidence": [ { "database": "UniProtKB", "id": "A8DZ10", "url": "https://www.uniprot.org/uniprotkb/A8DZ10" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8DZ10-1" }, { "uniprot_canonical_ac": "A8JNJ6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JNJ6", "url": "https://www.uniprot.org/uniprotkb/A8JNJ6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 4337, "chemical_mass": 497554.0, "gene_names": "kst;CG12008;Dmel\\CG12008;Dmel_CG12008;Karst;Kst;Spec-beta[[H]];beta-Spectrin;betaH-Spec;betaH-spectrin;betaHSpec;betaHS;betaH;beta[[H]]-SPEC;beta[[H]]-Spectrin;beta[[H]]-Spec;beta[[H]]-Sp;beta[[H]]-spec;beta[[H]]spectrin;beta[[H]];beta[[Heavy]]spectrin;beta[[heavy]]-Spectrin;beta[[heavy]]-Spec;beta[[heavy]]spectrin;betah-Spec;kst;l(3)01318", "protein_name": "", "disease": [], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A8JNJ6", "url": "https://www.uniprot.org/uniprotkb/A8JNJ6" } ], "pmid": "" }, { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "A8JNJ6", "url": "https://www.uniprot.org/uniprotkb/A8JNJ6" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A8JNJ6", "url": "https://www.uniprot.org/uniprotkb/A8JNJ6" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A8JNJ6", "url": "https://www.uniprot.org/uniprotkb/A8JNJ6" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A8JNJ6", "url": "https://www.uniprot.org/uniprotkb/A8JNJ6" } ], "pmid": "" } ], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A8JNJ6", "url": "https://www.uniprot.org/uniprotkb/A8JNJ6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A8JNJ6", "url": "https://www.uniprot.org/uniprotkb/A8JNJ6" } ], "pmid": "" }, { "name": "cell junction", "id": "GO:0030054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030054", "evidence": [ { "database": "UniProtKB", "id": "A8JNJ6", "url": "https://www.uniprot.org/uniprotkb/A8JNJ6" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A8JNJ6", "url": "https://www.uniprot.org/uniprotkb/A8JNJ6" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton", "id": "GO:0030864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030864", "evidence": [ { "database": "UniProtKB", "id": "A8JNJ6", "url": "https://www.uniprot.org/uniprotkb/A8JNJ6" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "A8JNJ6", "url": "https://www.uniprot.org/uniprotkb/A8JNJ6" } ], "pmid": "" }, { "name": "apicolateral plasma membrane", "id": "GO:0016327", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016327", "evidence": [ { "database": "UniProtKB", "id": "A8JNJ6", "url": "https://www.uniprot.org/uniprotkb/A8JNJ6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A8JNJ6", "url": "https://www.uniprot.org/uniprotkb/A8JNJ6" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A8JNJ6", "url": "https://www.uniprot.org/uniprotkb/A8JNJ6" } ], "pmid": "" }, { "name": "plasma membrane organization", "id": "GO:0007009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007009", "evidence": [ { "database": "UniProtKB", "id": "A8JNJ6", "url": "https://www.uniprot.org/uniprotkb/A8JNJ6" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A8JNJ6", "url": "https://www.uniprot.org/uniprotkb/A8JNJ6" } ], "pmid": "" }, { "name": "actin filament capping", "id": "GO:0051693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051693", "evidence": [ { "database": "UniProtKB", "id": "A8JNJ6", "url": "https://www.uniprot.org/uniprotkb/A8JNJ6" } ], "pmid": "" }, { "name": "wound healing", "id": "GO:0042060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042060", "evidence": [ { "database": "UniProtKB", "id": "A8JNJ6", "url": "https://www.uniprot.org/uniprotkb/A8JNJ6" } ], "pmid": "" }, { "name": "zonula adherens assembly", "id": "GO:0045186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045186", "evidence": [ { "database": "UniProtKB", "id": "A8JNJ6", "url": "https://www.uniprot.org/uniprotkb/A8JNJ6" } ], "pmid": "" }, { "name": "endosome transport via multivesicular body sorting pathway", "id": "GO:0032509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032509", "evidence": [ { "database": "UniProtKB", "id": "A8JNJ6", "url": "https://www.uniprot.org/uniprotkb/A8JNJ6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A8JNJ6-1", "start_pos": "3705", "end_pos": "3705", "site_lbl": "Thr3705", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3705, "start_aa": "Thr", "end_pos": 3705, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3705", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A8JNJ6-1", "start_pos": "4185", "end_pos": "4185", "site_lbl": "Thr4185", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 4185, "start_aa": "Thr", "end_pos": 4185, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr4185", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A8JNJ6", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A8JNJ6" } ] } ] }, { "uniprot_canonical_ac": "A8JNJ6-1", "start_pos": "4186", "end_pos": "4186", "site_lbl": "Thr4186", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 4186, "start_aa": "Thr", "end_pos": 4186, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr4186", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A8JNJ6", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A8JNJ6" } ] } ] }, { "uniprot_canonical_ac": "A8JNJ6-1", "start_pos": "4187", "end_pos": "4187", "site_lbl": "Thr4187", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 4187, "start_aa": "Thr", "end_pos": 4187, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr4187", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A8JNJ6", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A8JNJ6" } ] } ] }, { "uniprot_canonical_ac": "A8JNJ6-1", "start_pos": "4189", "end_pos": "4189", "site_lbl": "Thr4189", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 4189, "start_aa": "Thr", "end_pos": 4189, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr4189", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A8JNJ6", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A8JNJ6" } ] } ] }, { "uniprot_canonical_ac": "A8JNJ6-1", "start_pos": "4190", "end_pos": "4190", "site_lbl": "Thr4190", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 4190, "start_aa": "Thr", "end_pos": 4190, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr4190", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A8JNJ6", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A8JNJ6" } ] } ] } ], "record_id": "A8JNJ6-1" }, { "uniprot_canonical_ac": "B7Z0Z5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7Z0Z5", "url": "https://www.uniprot.org/uniprotkb/B7Z0Z5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 527, "chemical_mass": 58656.0, "gene_names": "Dmel\\CG4678;CG4678;Dmel\\CG4678;Dmel_CG4678", "protein_name": "Peptidase M14 domain-containing protein", "disease": [], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "B7Z0Z5", "url": "https://www.uniprot.org/uniprotkb/B7Z0Z5" } ], "pmid": "" }, { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "B7Z0Z5", "url": "https://www.uniprot.org/uniprotkb/B7Z0Z5" } ], "pmid": "" }, { "name": "peptide metabolic process", "id": "GO:0006518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006518", "evidence": [ { "database": "UniProtKB", "id": "B7Z0Z5", "url": "https://www.uniprot.org/uniprotkb/B7Z0Z5" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "B7Z0Z5", "url": "https://www.uniprot.org/uniprotkb/B7Z0Z5" } ], "pmid": "" }, { "name": "metallocarboxypeptidase activity", "id": "GO:0004181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004181", "evidence": [ { "database": "UniProtKB", "id": "B7Z0Z5", "url": "https://www.uniprot.org/uniprotkb/B7Z0Z5" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "B7Z0Z5", "url": "https://www.uniprot.org/uniprotkb/B7Z0Z5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "B7Z0Z5-1" }, { "uniprot_canonical_ac": "A8JRH0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JRH0", "url": "https://www.uniprot.org/uniprotkb/A8JRH0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 185, "chemical_mass": 21342.0, "gene_names": "Dmel\\CG34299;CG34299;Dmel\\CG34299;Dmel_CG34299", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8JRH0-1" }, { "uniprot_canonical_ac": "Q9VGX7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VGX7", "url": "https://www.uniprot.org/uniprotkb/Q9VGX7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 522, "chemical_mass": 57957.0, "gene_names": "Dmel\\CG14691;CG14691;Dmel\\CG14691;Dmel_CG14691", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VGX7", "url": "https://www.uniprot.org/uniprotkb/Q9VGX7" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "Q9VGX7", "url": "https://www.uniprot.org/uniprotkb/Q9VGX7" } ], "pmid": "" } ], "biological_process": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "Q9VGX7", "url": "https://www.uniprot.org/uniprotkb/Q9VGX7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VGX7-1" }, { "uniprot_canonical_ac": "Q9VAF2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VAF2", "url": "https://www.uniprot.org/uniprotkb/Q9VAF2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 309, "chemical_mass": 35405.0, "gene_names": "Dmel\\CG15514;CC30;CG15514;Dmel\\CG15514;Dmel_CG15514", "protein_name": "BED-type domain-containing protein", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q9VAF2", "url": "https://www.uniprot.org/uniprotkb/Q9VAF2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VAF2", "url": "https://www.uniprot.org/uniprotkb/Q9VAF2" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q9VAF2", "url": "https://www.uniprot.org/uniprotkb/Q9VAF2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VAF2-1" }, { "uniprot_canonical_ac": "B7Z0M0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7Z0M0", "url": "https://www.uniprot.org/uniprotkb/B7Z0M0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 122, "chemical_mass": 13757.0, "gene_names": "Vti1b;CG31232;CG44009;CG7682;Dmel\\CG44009;Dmel_CG44009;EP(3)1037;Vti1b;koko", "protein_name": "", "disease": [], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "B7Z0M0", "url": "https://www.uniprot.org/uniprotkb/B7Z0M0" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "B7Z0M0", "url": "https://www.uniprot.org/uniprotkb/B7Z0M0" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "B7Z0M0", "url": "https://www.uniprot.org/uniprotkb/B7Z0M0" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "B7Z0M0", "url": "https://www.uniprot.org/uniprotkb/B7Z0M0" } ], "pmid": "" } ], "molecular_function": [ { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "B7Z0M0", "url": "https://www.uniprot.org/uniprotkb/B7Z0M0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "B7Z0M0-1" }, { "uniprot_canonical_ac": "Q9VBJ2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBJ2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2802, "chemical_mass": 317249.0, "gene_names": "Nf1;CG8318;Dmel\\CG8318;Dmel_CG8318;FBpp0084326;NF-1;NF1;Nf-1;Nf1;dNF1;dNf1;nf1", "protein_name": "", "disease": [ { "disease_id": "DOID:0050458", "name": "juvenile myelomonocytic leukemia", "description": "A myelodysplastic/myeloproliferative neoplasm that is characterized by the uncontrolled growth of monocytes.", "url": "https://disease-ontology.org/term/DOID:0050458", "evidence": [ { "id": "0050458", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050458" } ], "weight": 0.0 }, { "disease_id": "DOID:0070482", "name": "spinal neurofibromatosis", "description": "A neurofibromatosis 1 characterized by bilateral neurofibromas of all spinal roots.", "url": "https://disease-ontology.org/term/DOID:0070482", "evidence": [ { "id": "0070482", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070482" } ], "weight": 0.0 }, { "disease_id": "DOID:0070483", "name": "Watson syndrome", "description": "A RASopathy characterized by pulmonic stenosis, cafe-au-lait macules, decreased intellectual ability, and short stature that has_material_basis_in heterozygous mutation in the NF1 gene on chromosome 17q11.2.", "url": "https://disease-ontology.org/term/DOID:0070483", "evidence": [ { "id": "0070483", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070483" } ], "weight": 0.0 }, { "disease_id": "DOID:0080199", "name": "colorectal carcinoma", "description": "A colorectal cancer that arises from the colon or rectum and invades through the muscularis mucosa into the submucosa.", "url": "https://disease-ontology.org/term/DOID:0080199", "evidence": [ { "id": "0080199", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080199" } ], "weight": 0.0 }, { "disease_id": "DOID:0111253", "name": "neurofibromatosis 1", "description": "A neurofibromatosis characterized by multiple cafe-au-lait macules, skin fold freckling, neurofibromas, optic gliomas, Lisch nodules or choroidal abnormalities in the eye, or a specific bone abnormality that has_material_basis_in the NF1 gene on chromosome 17q11.2. Bone abnormalities include a distinctive osseous lesion such as sphenoid dysplasia, anterolateral bowing of the tibia, or pseudarthrosis of a long bone.", "url": "https://disease-ontology.org/term/DOID:0111253", "evidence": [ { "id": "0111253", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111253" } ], "weight": 0.0 }, { "disease_id": "DOID:0111683", "name": "neurofibromatosis-Noonan syndrome", "description": "A RASopathy characterized by neurofibromatosis and manifestations of Noonan syndrome including short stature, ptosis, midface hypoplasia, webbed neck, learning disabilities, and muscle weakness that has_material_basis_in heterozygous mutation in NF1 on chromosome 17q11.2.", "url": "https://disease-ontology.org/term/DOID:0111683", "evidence": [ { "id": "0111683", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111683" } ], "weight": 0.0 }, { "disease_id": "DOID:1094", "name": "attention deficit hyperactivity disorder", "description": "A specific developmental disorder that is characterized by co-existence of attentional problems and hyperactivity, with each behavior occurring infrequently alone and symptoms starting before seven years of age.", "url": "https://disease-ontology.org/term/DOID:1094", "evidence": [ { "id": "1094", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1094" } ], "weight": 0.0 }, { "disease_id": "DOID:11446", "name": "sciatic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:11446", "evidence": [ { "id": "11446", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11446" } ], "weight": 0.0 }, { "disease_id": "DOID:12849", "name": "autistic disorder", "description": "An autism spectrum disorder that is characterized by symptoms across all three symptom domains (communication, social, restricted repetitive interests and behaviors), delayed language development, and symptom onset prior to age 3 years.", "url": "https://disease-ontology.org/term/DOID:12849", "evidence": [ { "id": "12849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12849" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:3069", "name": "malignant astrocytoma", "description": "A malignant glioma that is has_material_basis_in astrocyte cells, a type of star-shaped glial cell, located in the brain and spinal cord.", "url": "https://disease-ontology.org/term/DOID:3069", "evidence": [ { "id": "3069", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3069" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:4992", "name": "optic nerve glioma", "description": "", "url": "https://disease-ontology.org/term/DOID:4992", "evidence": [ { "id": "4992", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4992" } ], "weight": 0.0 }, { "disease_id": "DOID:5151", "name": "plexiform neurofibroma", "description": "", "url": "https://disease-ontology.org/term/DOID:5151", "evidence": [ { "id": "5151", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5151" } ], "weight": 0.0 }, { "disease_id": "DOID:535", "name": "sleep disorder", "description": "A disease of mental health that involves disruption of sleep patterns.", "url": "https://disease-ontology.org/term/DOID:535", "evidence": [ { "id": "535", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:535" } ], "weight": 0.0 }, { "disease_id": "DOID:8712", "name": "neurofibromatosis", "description": "", "url": "https://disease-ontology.org/term/DOID:8712", "evidence": [ { "id": "8712", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8712" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "Q9VBJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBJ2" } ], "pmid": "" } ], "biological_process": [ { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "Q9VBJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBJ2" } ], "pmid": "" }, { "name": "adult locomotory behavior", "id": "GO:0008344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008344", "evidence": [ { "database": "UniProtKB", "id": "Q9VBJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBJ2" } ], "pmid": "" }, { "name": "regulation of multicellular organism growth", "id": "GO:0040014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040014", "evidence": [ { "database": "UniProtKB", "id": "Q9VBJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBJ2" } ], "pmid": "" }, { "name": "short-term memory", "id": "GO:0007614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007614", "evidence": [ { "database": "UniProtKB", "id": "Q9VBJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBJ2" } ], "pmid": "" }, { "name": "Ras protein signal transduction", "id": "GO:0007265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007265", "evidence": [ { "database": "UniProtKB", "id": "Q9VBJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBJ2" } ], "pmid": "" }, { "name": "long-term memory", "id": "GO:0007616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007616", "evidence": [ { "database": "UniProtKB", "id": "Q9VBJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBJ2" } ], "pmid": "" }, { "name": "olfactory learning", "id": "GO:0008355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008355", "evidence": [ { "database": "UniProtKB", "id": "Q9VBJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBJ2" } ], "pmid": "" }, { "name": "locomotor rhythm", "id": "GO:0045475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045475", "evidence": [ { "database": "UniProtKB", "id": "Q9VBJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBJ2" } ], "pmid": "" }, { "name": "response to heat", "id": "GO:0009408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009408", "evidence": [ { "database": "UniProtKB", "id": "Q9VBJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBJ2" } ], "pmid": "" }, { "name": "positive regulation of multicellular organism growth", "id": "GO:0040018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040018", "evidence": [ { "database": "UniProtKB", "id": "Q9VBJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBJ2" } ], "pmid": "" }, { "name": "regulation of Ras protein signal transduction", "id": "GO:0046578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046578", "evidence": [ { "database": "UniProtKB", "id": "Q9VBJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBJ2" } ], "pmid": "" }, { "name": "determination of adult lifespan", "id": "GO:0008340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008340", "evidence": [ { "database": "UniProtKB", "id": "Q9VBJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBJ2" } ], "pmid": "" }, { "name": "perineurial glial growth", "id": "GO:0042066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042066", "evidence": [ { "database": "UniProtKB", "id": "Q9VBJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBJ2" } ], "pmid": "" }, { "name": "negative regulation of synaptic assembly at neuromuscular junction", "id": "GO:0045886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045886", "evidence": [ { "database": "UniProtKB", "id": "Q9VBJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBJ2" } ], "pmid": "" }, { "name": "regulation of circadian rhythm", "id": "GO:0042752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042752", "evidence": [ { "database": "UniProtKB", "id": "Q9VBJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBJ2" } ], "pmid": "" }, { "name": "regulation of intracellular signal transduction", "id": "GO:1902531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902531", "evidence": [ { "database": "UniProtKB", "id": "Q9VBJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBJ2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VBJ2-1", "start_pos": "1617", "end_pos": "1617", "site_lbl": "Thr1617", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1617, "start_aa": "Thr", "end_pos": 1617, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1617", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VBJ2", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VBJ2" } ] } ] }, { "uniprot_canonical_ac": "Q9VBJ2-1", "start_pos": "1791", "end_pos": "1791", "site_lbl": "Thr1791", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1791, "start_aa": "Thr", "end_pos": 1791, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1791", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VBJ2-1" }, { "uniprot_canonical_ac": "Q0KHY7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0KHY7", "url": "https://www.uniprot.org/uniprotkb/Q0KHY7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 509, "chemical_mass": 59032.0, "gene_names": "Dmel\\CG15539;CG15539-NE4;CG15539;Dmel\\CG15539;Dmel_CG15539", "protein_name": "procollagen-proline 4-dioxygenase", "disease": [], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q0KHY7", "url": "https://www.uniprot.org/uniprotkb/Q0KHY7" } ], "pmid": "" }, { "name": "L-ascorbic acid binding", "id": "GO:0031418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031418", "evidence": [ { "database": "UniProtKB", "id": "Q0KHY7", "url": "https://www.uniprot.org/uniprotkb/Q0KHY7" } ], "pmid": "" }, { "name": "procollagen-proline 4-dioxygenase activity", "id": "GO:0004656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004656", "evidence": [ { "database": "UniProtKB", "id": "Q0KHY7", "url": "https://www.uniprot.org/uniprotkb/Q0KHY7" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "Q0KHY7", "url": "https://www.uniprot.org/uniprotkb/Q0KHY7" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q0KHY7", "url": "https://www.uniprot.org/uniprotkb/Q0KHY7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q0KHY7-1" }, { "uniprot_canonical_ac": "E1JH39-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JH39", "url": "https://www.uniprot.org/uniprotkb/E1JH39" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1028, "chemical_mass": 115115.0, "gene_names": "MCPH1;CG13184;CG30038;CG42572;CG8981;Dmcph1;Dmel\\CG42572;Dmel_CG42572;MCPH1;awol;dMCPH1;mcph1;p91", "protein_name": "", "disease": [ { "disease_id": "DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050866", "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ], "weight": 0.0 }, { "disease_id": "DOID:0070285", "name": "primary autosomal recessive microcephaly 1", "description": "A primary autosomal recessive microcephaly that has_material_basis_in homozygous or compound heterozygous mutation in the MCPH1 gene on chromosome 8p23.", "url": "https://disease-ontology.org/term/DOID:0070285", "evidence": [ { "id": "0070285", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070285" } ], "weight": 0.0 }, { "disease_id": "DOID:0070296", "name": "autosomal recessive primary microcephaly", "description": "A primary microcephaly characterized by microcephaly present at birth, where the brain is small but has normal architecture, and nonprogressive mental retardation that has_material_basis_in an autosomal recessive mutation.", "url": "https://disease-ontology.org/term/DOID:0070296", "evidence": [ { "id": "0070296", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070296" } ], "weight": 0.0 }, { "disease_id": "DOID:10907", "name": "microcephaly", "description": "A congenital nervous system abnormality that is characterized by a significantly smaller than normal head in infants.", "url": "https://disease-ontology.org/term/DOID:10907", "evidence": [ { "id": "10907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10907" } ], "weight": 0.0 }, { "disease_id": "DOID:1380", "name": "endometrial cancer", "description": "A uterine cancer that is located_in tissues lining the uterus.", "url": "https://disease-ontology.org/term/DOID:1380", "evidence": [ { "id": "1380", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1380" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:4451", "name": "renal carcinoma", "description": "A kidney cancer that derives_from the lining of the proximal convoluted tubule (the very small tubes in the kidney that filter the blood and remove waste products).", "url": "https://disease-ontology.org/term/DOID:4451", "evidence": [ { "id": "4451", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4451" } ], "weight": 0.0 } ], "biological_process": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "E1JH39", "url": "https://www.uniprot.org/uniprotkb/E1JH39" } ], "pmid": "" }, { "name": "mitotic cell cycle, embryonic", "id": "GO:0045448", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045448", "evidence": [ { "database": "UniProtKB", "id": "E1JH39", "url": "https://www.uniprot.org/uniprotkb/E1JH39" } ], "pmid": "" }, { "name": "pole cell formation", "id": "GO:0007279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007279", "evidence": [ { "database": "UniProtKB", "id": "E1JH39", "url": "https://www.uniprot.org/uniprotkb/E1JH39" } ], "pmid": "" }, { "name": "mushroom body development", "id": "GO:0016319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016319", "evidence": [ { "database": "UniProtKB", "id": "E1JH39", "url": "https://www.uniprot.org/uniprotkb/E1JH39" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1JH39", "url": "https://www.uniprot.org/uniprotkb/E1JH39" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "E1JH39-1", "start_pos": "736", "end_pos": "736", "site_lbl": "Thr736", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 736, "start_aa": "Thr", "end_pos": 736, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr736", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "E1JH39-1" }, { "uniprot_canonical_ac": "B7Z0B0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7Z0B0", "url": "https://www.uniprot.org/uniprotkb/B7Z0B0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 780, "chemical_mass": 85294.0, "gene_names": "sowah;BcDNA:GM09162;CG10632;Dmel\\CG10632;Dmel_CG10632;Sowah;sowah", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "B7Z0B0-1" }, { "uniprot_canonical_ac": "Q7KQN5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KQN5", "url": "https://www.uniprot.org/uniprotkb/Q7KQN5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1150, "chemical_mass": 124143.0, "gene_names": "dati;CG10204;CG2052;DmLin29;Dmel\\CG2052;Dmel_CG2052;Lin29;dati", "protein_name": "", "disease": [], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q7KQN5", "url": "https://www.uniprot.org/uniprotkb/Q7KQN5" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q7KQN5", "url": "https://www.uniprot.org/uniprotkb/Q7KQN5" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "Q7KQN5", "url": "https://www.uniprot.org/uniprotkb/Q7KQN5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q7KQN5", "url": "https://www.uniprot.org/uniprotkb/Q7KQN5" } ], "pmid": "" } ], "biological_process": [ { "name": "adult locomotory behavior", "id": "GO:0008344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008344", "evidence": [ { "database": "UniProtKB", "id": "Q7KQN5", "url": "https://www.uniprot.org/uniprotkb/Q7KQN5" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "Q7KQN5", "url": "https://www.uniprot.org/uniprotkb/Q7KQN5" } ], "pmid": "" }, { "name": "generation of neurons", "id": "GO:0048699", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048699", "evidence": [ { "database": "UniProtKB", "id": "Q7KQN5", "url": "https://www.uniprot.org/uniprotkb/Q7KQN5" } ], "pmid": "" }, { "name": "positive regulation of female receptivity", "id": "GO:0045925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045925", "evidence": [ { "database": "UniProtKB", "id": "Q7KQN5", "url": "https://www.uniprot.org/uniprotkb/Q7KQN5" } ], "pmid": "" }, { "name": "mushroom body development", "id": "GO:0016319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016319", "evidence": [ { "database": "UniProtKB", "id": "Q7KQN5", "url": "https://www.uniprot.org/uniprotkb/Q7KQN5" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q7KQN5", "url": "https://www.uniprot.org/uniprotkb/Q7KQN5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q7KQN5", "url": "https://www.uniprot.org/uniprotkb/Q7KQN5" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q7KQN5", "url": "https://www.uniprot.org/uniprotkb/Q7KQN5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7KQN5-1", "start_pos": "1050", "end_pos": "1050", "site_lbl": "Thr1050", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1050, "start_aa": "Thr", "end_pos": 1050, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1050", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q7KQN5-1" }, { "uniprot_canonical_ac": "H9XVM9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "H9XVM9", "url": "https://www.uniprot.org/uniprotkb/H9XVM9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 905, "chemical_mass": 101617.0, "gene_names": "Dmel\\CG1674;CG1674;Dmel\\CG1674;Dmel_CG1674", "protein_name": "", "disease": [ { "disease_id": "DOID:784", "name": "chronic kidney disease", "description": "A kidney failure that is characterized by the gradual loss of kidney function, present for a minimum of 3 months. CKD is classified based on cause, glomerular filtration rate (GFR) category (G2-G5), and albuminuria category (A1-A3).", "url": "https://disease-ontology.org/term/DOID:784", "evidence": [ { "id": "784", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:784" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "H9XVM9", "url": "https://www.uniprot.org/uniprotkb/H9XVM9" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "H9XVM9", "url": "https://www.uniprot.org/uniprotkb/H9XVM9" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "H9XVM9", "url": "https://www.uniprot.org/uniprotkb/H9XVM9" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of actin filament bundle assembly", "id": "GO:0032233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032233", "evidence": [ { "database": "UniProtKB", "id": "H9XVM9", "url": "https://www.uniprot.org/uniprotkb/H9XVM9" } ], "pmid": "" } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "H9XVM9", "url": "https://www.uniprot.org/uniprotkb/H9XVM9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "H9XVM9-1", "start_pos": "174", "end_pos": "174", "site_lbl": "Thr174", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 174, "start_aa": "Thr", "end_pos": 174, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr174", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "H9XVM9-1", "start_pos": "247", "end_pos": "247", "site_lbl": "Thr247", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 247, "start_aa": "Thr", "end_pos": 247, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr247", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "H9XVM9", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=H9XVM9" } ] } ] }, { "uniprot_canonical_ac": "H9XVM9-1", "start_pos": "250", "end_pos": "250", "site_lbl": "Thr250", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 250, "start_aa": "Thr", "end_pos": 250, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr250", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "H9XVM9", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=H9XVM9" } ] } ] }, { "uniprot_canonical_ac": "H9XVM9-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Ser55", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 55, "start_aa": "Ser", "end_pos": 55, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser55", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "H9XVM9", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=H9XVM9" } ] } ] } ], "record_id": "H9XVM9-1" }, { "uniprot_canonical_ac": "M9NGY4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NGY4", "url": "https://www.uniprot.org/uniprotkb/M9NGY4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1885, "chemical_mass": 205249.0, "gene_names": "ZAP3;CG12646;CG12647;CG2971;CG32685;Dmel\\CG32685;Dmel_CG32685;ZAP3;Zap3", "protein_name": "YLP motif-containing protein 1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9NGY4", "url": "https://www.uniprot.org/uniprotkb/M9NGY4" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "M9NGY4", "url": "https://www.uniprot.org/uniprotkb/M9NGY4" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein phosphatase 1 binding", "id": "GO:0008157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008157", "evidence": [ { "database": "UniProtKB", "id": "M9NGY4", "url": "https://www.uniprot.org/uniprotkb/M9NGY4" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "M9NGY4", "url": "https://www.uniprot.org/uniprotkb/M9NGY4" } ], "pmid": "" }, { "name": "regulation of telomere maintenance", "id": "GO:0032204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032204", "evidence": [ { "database": "UniProtKB", "id": "M9NGY4", "url": "https://www.uniprot.org/uniprotkb/M9NGY4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9NGY4-1", "start_pos": "149", "end_pos": "149", "site_lbl": "Thr149", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 149, "start_aa": "Thr", "end_pos": 149, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr149", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9NGY4-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Thr14", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 14, "start_aa": "Thr", "end_pos": 14, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr14", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9NGY4-1", "start_pos": "820", "end_pos": "820", "site_lbl": "Thr820", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 820, "start_aa": "Thr", "end_pos": 820, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr820", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9NGY4-1" }, { "uniprot_canonical_ac": "Q7KTF8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KTF8", "url": "https://www.uniprot.org/uniprotkb/Q7KTF8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 523, "chemical_mass": 59093.0, "gene_names": "nAChRalpha6;AChRalpha6;BcDNA:GH01410;CG4128;CT13662;Dalpha6;Dmel\\CG4128;Dmel_CG4128;alpha6;dalpha6;das;nACRalpha-30D;nAChR alpha 6;nAChR-alpha30D;nAChRAlpha-30D;nAChRalpha-30D;nAChRalpha6;nAChRalpha;nAChR;nAChralpha6;nAcR-alpha-30D;nAcRalpha-30D;nAchR_alpha6;rsn", "protein_name": "", "disease": [ { "disease_id": "DOID:0050742", "name": "nicotine dependence", "description": "A substance dependence that is characterized by a physical dependence on nicotine.", "url": "https://disease-ontology.org/term/DOID:0050742", "evidence": [ { "id": "0050742", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050742" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:12217", "name": "Lewy body dementia", "description": "A dementia that is characterized by the development of abnormal proteinaceous (alpha-synuclein) cytoplasmic inclusions, called Lewy bodies, throughout the brain that results in progressive decline in mental abilities that has_material_basis_in accumulation of alpha-synuclein, SCNA, (protein). The causal mutation might be in SCNA or SCNB or some other gene(s) but the end result is always accumulation of SCNA in Lewy bodies.", "url": "https://disease-ontology.org/term/DOID:12217", "evidence": [ { "id": "12217", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12217" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:1561", "name": "cognitive disorder", "description": "A disease of mental health that affects cognitive functions including memory processing, perception and problem solving.", "url": "https://disease-ontology.org/term/DOID:1561", "evidence": [ { "id": "1561", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1561" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:7148", "name": "rheumatoid arthritis", "description": "An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint.", "url": "https://disease-ontology.org/term/DOID:7148", "evidence": [ { "id": "7148", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7148" } ], "weight": 0.0 }, { "disease_id": "DOID:7474", "name": "malignant pleural mesothelioma", "description": "A pleural cancer that has_material_basis_in mesothelium cells.", "url": "https://disease-ontology.org/term/DOID:7474", "evidence": [ { "id": "7474", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7474" } ], "weight": 0.0 }, { "disease_id": "DOID:8577", "name": "ulcerative colitis", "description": "A colitis that is predominantly confined to the mucosa located_in colon and includes characteristic ulcers, or open sores.", "url": "https://disease-ontology.org/term/DOID:8577", "evidence": [ { "id": "8577", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8577" } ], "weight": 0.0 }, { "disease_id": "DOID:8778", "name": "Crohn's disease", "description": "An intestinal disease that involves inflammation located_in intestine.", "url": "https://disease-ontology.org/term/DOID:8778", "evidence": [ { "id": "8778", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8778" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "Q7KTF8", "url": "https://www.uniprot.org/uniprotkb/Q7KTF8" } ], "pmid": "" }, { "name": "acetylcholine-gated monoatomic cation-selective channel activity", "id": "GO:0022848", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022848", "evidence": [ { "database": "UniProtKB", "id": "Q7KTF8", "url": "https://www.uniprot.org/uniprotkb/Q7KTF8" } ], "pmid": "" }, { "name": "transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential", "id": "GO:1904315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904315", "evidence": [ { "database": "UniProtKB", "id": "Q7KTF8", "url": "https://www.uniprot.org/uniprotkb/Q7KTF8" } ], "pmid": "" }, { "name": "excitatory extracellular ligand-gated monoatomic ion channel activity", "id": "GO:0005231", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005231", "evidence": [ { "database": "UniProtKB", "id": "Q7KTF8", "url": "https://www.uniprot.org/uniprotkb/Q7KTF8" } ], "pmid": "" } ], "cellular_component": [ { "name": "acetylcholine-gated channel complex", "id": "GO:0005892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005892", "evidence": [ { "database": "UniProtKB", "id": "Q7KTF8", "url": "https://www.uniprot.org/uniprotkb/Q7KTF8" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "Q7KTF8", "url": "https://www.uniprot.org/uniprotkb/Q7KTF8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q7KTF8", "url": "https://www.uniprot.org/uniprotkb/Q7KTF8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q7KTF8", "url": "https://www.uniprot.org/uniprotkb/Q7KTF8" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "Q7KTF8", "url": "https://www.uniprot.org/uniprotkb/Q7KTF8" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "Q7KTF8", "url": "https://www.uniprot.org/uniprotkb/Q7KTF8" } ], "pmid": "" } ], "biological_process": [ { "name": "muscle cell cellular homeostasis", "id": "GO:0046716", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046716", "evidence": [ { "database": "UniProtKB", "id": "Q7KTF8", "url": "https://www.uniprot.org/uniprotkb/Q7KTF8" } ], "pmid": "" }, { "name": "monoatomic cation transport", "id": "GO:0006812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006812", "evidence": [ { "database": "UniProtKB", "id": "Q7KTF8", "url": "https://www.uniprot.org/uniprotkb/Q7KTF8" } ], "pmid": "" }, { "name": "synaptic transmission, cholinergic", "id": "GO:0007271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007271", "evidence": [ { "database": "UniProtKB", "id": "Q7KTF8", "url": "https://www.uniprot.org/uniprotkb/Q7KTF8" } ], "pmid": "" }, { "name": "regulation of membrane potential", "id": "GO:0042391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042391", "evidence": [ { "database": "UniProtKB", "id": "Q7KTF8", "url": "https://www.uniprot.org/uniprotkb/Q7KTF8" } ], "pmid": "" }, { "name": "monoatomic ion transmembrane transport", "id": "GO:0034220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034220", "evidence": [ { "database": "UniProtKB", "id": "Q7KTF8", "url": "https://www.uniprot.org/uniprotkb/Q7KTF8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7KTF8-1", "start_pos": "392", "end_pos": "392", "site_lbl": "Thr392", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 392, "start_aa": "Thr", "end_pos": 392, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr392", "evidence": [ { "id": "28604694", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28604694" }, { "id": "Q7KTF8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q7KTF8" } ] } ] } ], "record_id": "Q7KTF8-1" }, { "uniprot_canonical_ac": "B6VQ99-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B6VQ99", "url": "https://www.uniprot.org/uniprotkb/B6VQ99" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 382, "chemical_mass": 43234.0, "gene_names": "Neu2;CG7204;Dmel\\CG7204;Dmel_CG7204;Neu2;neu2", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B6VQ99", "url": "https://www.uniprot.org/uniprotkb/B6VQ99" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "B6VQ99", "url": "https://www.uniprot.org/uniprotkb/B6VQ99" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "B6VQ99", "url": "https://www.uniprot.org/uniprotkb/B6VQ99" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "B6VQ99", "url": "https://www.uniprot.org/uniprotkb/B6VQ99" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "B6VQ99", "url": "https://www.uniprot.org/uniprotkb/B6VQ99" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "B6VQ99", "url": "https://www.uniprot.org/uniprotkb/B6VQ99" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "B6VQ99", "url": "https://www.uniprot.org/uniprotkb/B6VQ99" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "B6VQ99", "url": "https://www.uniprot.org/uniprotkb/B6VQ99" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "B6VQ99", "url": "https://www.uniprot.org/uniprotkb/B6VQ99" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "B6VQ99-1" }, { "uniprot_canonical_ac": "Q8IQI0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQI0", "url": "https://www.uniprot.org/uniprotkb/Q8IQI0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1294, "chemical_mass": 131383.0, "gene_names": "Sap130;BcDNA:LD21213;CG11006;Dmel\\CG11006;Dmel_CG11006;SAP130;Sap130;l(3)06924", "protein_name": "", "disease": [ { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 }, { "disease_id": "DOID:9955", "name": "hypoplastic left heart syndrome", "description": "A congenital heart disease characterized by abnormal development of the left-sided structures of the heart.", "url": "https://disease-ontology.org/term/DOID:9955", "evidence": [ { "id": "9955", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9955" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q8IQI0", "url": "https://www.uniprot.org/uniprotkb/Q8IQI0" } ], "pmid": "" }, { "name": "Sin3-type complex", "id": "GO:0070822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070822", "evidence": [ { "database": "UniProtKB", "id": "Q8IQI0", "url": "https://www.uniprot.org/uniprotkb/Q8IQI0" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q8IQI0", "url": "https://www.uniprot.org/uniprotkb/Q8IQI0" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q8IQI0", "url": "https://www.uniprot.org/uniprotkb/Q8IQI0" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "Q8IQI0", "url": "https://www.uniprot.org/uniprotkb/Q8IQI0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8IQI0-1", "start_pos": "1085", "end_pos": "1085", "site_lbl": "Thr1085", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1085, "start_aa": "Thr", "end_pos": 1085, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1085", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q8IQI0-1", "start_pos": "1107", "end_pos": "1107", "site_lbl": "Thr1107", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1107, "start_aa": "Thr", "end_pos": 1107, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1107", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q8IQI0-1", "start_pos": "260", "end_pos": "260", "site_lbl": "Thr260", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 260, "start_aa": "Thr", "end_pos": 260, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr260", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q8IQI0-1", "start_pos": "427", "end_pos": "427", "site_lbl": "Thr427", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 427, "start_aa": "Thr", "end_pos": 427, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr427", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q8IQI0-1" }, { "uniprot_canonical_ac": "E1JJE6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JJE6", "url": "https://www.uniprot.org/uniprotkb/E1JJE6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 991, "chemical_mass": 108826.0, "gene_names": "OtopLa;CG11473;CG17761;CG42492;Dmel\\CG42492;Dmel_CG42492;OtopLA;OtopLa;anon-WO0140519.181;dmOTOPLa;dm_OtopLa;otopla", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1JJE6", "url": "https://www.uniprot.org/uniprotkb/E1JJE6" } ], "pmid": "" } ], "molecular_function": [ { "name": "proton channel activity", "id": "GO:0015252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015252", "evidence": [ { "database": "UniProtKB", "id": "E1JJE6", "url": "https://www.uniprot.org/uniprotkb/E1JJE6" } ], "pmid": "" }, { "name": "sour taste receptor activity", "id": "GO:0033040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033040", "evidence": [ { "database": "UniProtKB", "id": "E1JJE6", "url": "https://www.uniprot.org/uniprotkb/E1JJE6" } ], "pmid": "" } ], "biological_process": [ { "name": "detection of chemical stimulus involved in sensory perception of sour taste", "id": "GO:0001581", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001581", "evidence": [ { "database": "UniProtKB", "id": "E1JJE6", "url": "https://www.uniprot.org/uniprotkb/E1JJE6" } ], "pmid": "" }, { "name": "proton transmembrane transport", "id": "GO:1902600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902600", "evidence": [ { "database": "UniProtKB", "id": "E1JJE6", "url": "https://www.uniprot.org/uniprotkb/E1JJE6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "E1JJE6-1", "start_pos": "604", "end_pos": "604", "site_lbl": "Thr604", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 604, "start_aa": "Thr", "end_pos": 604, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr604", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "E1JJE6-1" }, { "uniprot_canonical_ac": "A8JUP5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JUP5", "url": "https://www.uniprot.org/uniprotkb/A8JUP5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 206, "chemical_mass": 23638.0, "gene_names": "Dmel\\CG12645;CG12645;Dmel\\CG12645;Dmel_CG12645", "protein_name": "LITAF domain-containing protein", "disease": [], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A8JUP5", "url": "https://www.uniprot.org/uniprotkb/A8JUP5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A8JUP5", "url": "https://www.uniprot.org/uniprotkb/A8JUP5" } ], "pmid": "" } ], "cellular_component": [ { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A8JUP5", "url": "https://www.uniprot.org/uniprotkb/A8JUP5" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A8JUP5", "url": "https://www.uniprot.org/uniprotkb/A8JUP5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8JUP5-1" }, { "uniprot_canonical_ac": "Q2PE08-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q2PE08", "url": "https://www.uniprot.org/uniprotkb/Q2PE08" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 355, "chemical_mass": 41231.0, "gene_names": "CG13904;CG13904;CG34057;Dmel\\CG34057;Dmel_CG34057;dC1GalT6", "protein_name": "Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q2PE08", "url": "https://www.uniprot.org/uniprotkb/Q2PE08" } ], "pmid": "" } ], "molecular_function": [ { "name": "manganese ion binding", "id": "GO:0030145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030145", "evidence": [ { "database": "UniProtKB", "id": "Q2PE08", "url": "https://www.uniprot.org/uniprotkb/Q2PE08" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "Q2PE08", "url": "https://www.uniprot.org/uniprotkb/Q2PE08" } ], "pmid": "" }, { "name": "glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity", "id": "GO:0016263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016263", "evidence": [ { "database": "UniProtKB", "id": "Q2PE08", "url": "https://www.uniprot.org/uniprotkb/Q2PE08" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q2PE08-1" }, { "uniprot_canonical_ac": "Q9V4E5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V4E5", "url": "https://www.uniprot.org/uniprotkb/Q9V4E5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1096, "chemical_mass": 123282.0, "gene_names": "Eph;CG1511;CT3831;DEK;Dek7;Dek;Deph;Dmel\\CG1511;Dmel_CG1511;EPH;Ek7;Eph;RPTK Dek7;dek;eph;lincRNA.923", "protein_name": "receptor protein-tyrosine kinase", "disease": [ { "disease_id": "DOID:0070611", "name": "autosomal dominant nonsyndromic deafness 88", "description": "An autosomal dominant nonsyndromic deafness characterized by postlingual progressive severe sensorineural hearing loss with tinnitus that has_material_basis_in heterozygous mutation in the EPHA10 gene on chromosome 1p34.", "url": "https://disease-ontology.org/term/DOID:0070611", "evidence": [ { "id": "0070611", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070611" } ], "weight": 0.0 }, { "disease_id": "DOID:0080685", "name": "aortic dissection", "description": "An aortic disease that is characterized by tearing of the intimal layer of the aorta resulting in separation of the layers of the aortic wall.", "url": "https://disease-ontology.org/term/DOID:0080685", "evidence": [ { "id": "0080685", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080685" } ], "weight": 0.0 }, { "disease_id": "DOID:0081030", "name": "central conducting lymphatic anomaly", "description": "A lymphatic system disease that is characterized by dysfunction of the thoracic duct or cisterna chyli, leading to a retrograde flux of lymphatic fluid or abnormal drainage of lymphatic fluid and that has_material_basis_in heterozygous mutation in the EPHB4 gene on chromosome 7q22.", "url": "https://disease-ontology.org/term/DOID:0081030", "evidence": [ { "id": "0081030", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081030" } ], "weight": 0.0 }, { "disease_id": "DOID:0110229", "name": "cataract 6 multiple types", "description": "A cataract that has_material_basis_in heterozygous mutation in the EPHA2 gene on chromosome 1p36.", "url": "https://disease-ontology.org/term/DOID:0110229", "evidence": [ { "id": "0110229", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110229" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:12365", "name": "malaria", "description": "A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle.", "url": "https://disease-ontology.org/term/DOID:12365", "evidence": [ { "id": "12365", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12365" } ], "weight": 0.0 }, { "disease_id": "DOID:1561", "name": "cognitive disorder", "description": "A disease of mental health that affects cognitive functions including memory processing, perception and problem solving.", "url": "https://disease-ontology.org/term/DOID:1561", "evidence": [ { "id": "1561", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1561" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:2218", "name": "blood platelet disease", "description": "A blood coagulation disease that is characterized by an abnormal increase or decrease in platelets or platelet dysfunction.", "url": "https://disease-ontology.org/term/DOID:2218", "evidence": [ { "id": "2218", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2218" } ], "weight": 0.0 }, { "disease_id": "DOID:264", "name": "hemangiopericytoma", "description": "A hemangiopericytic tumor that is a soft tissue sarcoma and originates in the pericytes in the walls of capillaries.", "url": "https://disease-ontology.org/term/DOID:264", "evidence": [ { "id": "264", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:264" } ], "weight": 0.0 }, { "disease_id": "DOID:2975", "name": "cystic kidney disease", "description": "A kidney disease that is characterized by the formation of cysts (fluid-filled sacs) in and around the kidney.", "url": "https://disease-ontology.org/term/DOID:2975", "evidence": [ { "id": "2975", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2975" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 }, { "disease_id": "DOID:3602", "name": "toxic encephalopathy", "description": "A nervous system disease that results from exposure to neurotoxicants and is characterized by an altered mental status, memory loss, and visual problems.", "url": "https://disease-ontology.org/term/DOID:3602", "evidence": [ { "id": "3602", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3602" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:526", "name": "human immunodeficiency virus infectious disease", "description": "A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.", "url": "https://disease-ontology.org/term/DOID:526", "evidence": [ { "id": "526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:526" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:75", "name": "lymphatic system disease", "description": "An immune system disease that is located_in the lymphatic system.", "url": "https://disease-ontology.org/term/DOID:75", "evidence": [ { "id": "75", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:75" } ], "weight": 0.0 }, { "disease_id": "DOID:8577", "name": "ulcerative colitis", "description": "A colitis that is predominantly confined to the mucosa located_in colon and includes characteristic ulcers, or open sores.", "url": "https://disease-ontology.org/term/DOID:8577", "evidence": [ { "id": "8577", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8577" } ], "weight": 0.0 }, { "disease_id": "DOID:9778", "name": "irritable bowel syndrome", "description": "An intestinal disease that is characterized by chronic abdominal pain, discomfort, bloating, and alteration of bowel habits in the absence of any detectable organic cause.", "url": "https://disease-ontology.org/term/DOID:9778", "evidence": [ { "id": "9778", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9778" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9V4E5", "url": "https://www.uniprot.org/uniprotkb/Q9V4E5" } ], "pmid": "" }, { "name": "transmembrane-ephrin receptor activity", "id": "GO:0005005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005005", "evidence": [ { "database": "UniProtKB", "id": "Q9V4E5", "url": "https://www.uniprot.org/uniprotkb/Q9V4E5" } ], "pmid": "" }, { "name": "transmembrane receptor protein tyrosine kinase activity", "id": "GO:0004714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004714", "evidence": [ { "database": "UniProtKB", "id": "Q9V4E5", "url": "https://www.uniprot.org/uniprotkb/Q9V4E5" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9V4E5", "url": "https://www.uniprot.org/uniprotkb/Q9V4E5" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "Q9V4E5", "url": "https://www.uniprot.org/uniprotkb/Q9V4E5" } ], "pmid": "" } ], "biological_process": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "Q9V4E5", "url": "https://www.uniprot.org/uniprotkb/Q9V4E5" } ], "pmid": "" }, { "name": "ephrin receptor signaling pathway", "id": "GO:0048013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048013", "evidence": [ { "database": "UniProtKB", "id": "Q9V4E5", "url": "https://www.uniprot.org/uniprotkb/Q9V4E5" } ], "pmid": "" }, { "name": "peripheral nervous system development", "id": "GO:0007422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007422", "evidence": [ { "database": "UniProtKB", "id": "Q9V4E5", "url": "https://www.uniprot.org/uniprotkb/Q9V4E5" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "Q9V4E5", "url": "https://www.uniprot.org/uniprotkb/Q9V4E5" } ], "pmid": "" }, { "name": "mushroom body development", "id": "GO:0016319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016319", "evidence": [ { "database": "UniProtKB", "id": "Q9V4E5", "url": "https://www.uniprot.org/uniprotkb/Q9V4E5" } ], "pmid": "" }, { "name": "melanotic encapsulation of foreign target", "id": "GO:0035011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035011", "evidence": [ { "database": "UniProtKB", "id": "Q9V4E5", "url": "https://www.uniprot.org/uniprotkb/Q9V4E5" } ], "pmid": "" }, { "name": "cell surface receptor protein tyrosine kinase signaling pathway", "id": "GO:0007169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007169", "evidence": [ { "database": "UniProtKB", "id": "Q9V4E5", "url": "https://www.uniprot.org/uniprotkb/Q9V4E5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V4E5-1" }, { "uniprot_canonical_ac": "Q8IPH8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IPH8", "url": "https://www.uniprot.org/uniprotkb/Q8IPH8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2122, "chemical_mass": 243303.0, "gene_names": "Myo28B1;28B;CG6976;DmVIIB;Dmel\\CG6976;Dmel_CG6976;Myo18;Myo28B1;Myo28B;VIIb 28B;myo 28B1;myo28B", "protein_name": "", "disease": [], "biological_process": [ { "name": "system development", "id": "GO:0048731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048731", "evidence": [ { "database": "UniProtKB", "id": "Q8IPH8", "url": "https://www.uniprot.org/uniprotkb/Q8IPH8" } ], "pmid": "" }, { "name": "actin filament-based movement", "id": "GO:0030048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030048", "evidence": [ { "database": "UniProtKB", "id": "Q8IPH8", "url": "https://www.uniprot.org/uniprotkb/Q8IPH8" } ], "pmid": "" }, { "name": "tissue development", "id": "GO:0009888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009888", "evidence": [ { "database": "UniProtKB", "id": "Q8IPH8", "url": "https://www.uniprot.org/uniprotkb/Q8IPH8" } ], "pmid": "" }, { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "Q8IPH8", "url": "https://www.uniprot.org/uniprotkb/Q8IPH8" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "Q8IPH8", "url": "https://www.uniprot.org/uniprotkb/Q8IPH8" } ], "pmid": "" }, { "name": "animal organ morphogenesis", "id": "GO:0009887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887", "evidence": [ { "database": "UniProtKB", "id": "Q8IPH8", "url": "https://www.uniprot.org/uniprotkb/Q8IPH8" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "Q8IPH8", "url": "https://www.uniprot.org/uniprotkb/Q8IPH8" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "Q8IPH8", "url": "https://www.uniprot.org/uniprotkb/Q8IPH8" } ], "pmid": "" }, { "name": "sensory organ development", "id": "GO:0007423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007423", "evidence": [ { "database": "UniProtKB", "id": "Q8IPH8", "url": "https://www.uniprot.org/uniprotkb/Q8IPH8" } ], "pmid": "" } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "Q8IPH8", "url": "https://www.uniprot.org/uniprotkb/Q8IPH8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q8IPH8", "url": "https://www.uniprot.org/uniprotkb/Q8IPH8" } ], "pmid": "" }, { "name": "microfilament motor activity", "id": "GO:0000146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000146", "evidence": [ { "database": "UniProtKB", "id": "Q8IPH8", "url": "https://www.uniprot.org/uniprotkb/Q8IPH8" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "Q8IPH8", "url": "https://www.uniprot.org/uniprotkb/Q8IPH8" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q8IPH8", "url": "https://www.uniprot.org/uniprotkb/Q8IPH8" } ], "pmid": "" }, { "name": "myosin complex", "id": "GO:0016459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016459", "evidence": [ { "database": "UniProtKB", "id": "Q8IPH8", "url": "https://www.uniprot.org/uniprotkb/Q8IPH8" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "Q8IPH8", "url": "https://www.uniprot.org/uniprotkb/Q8IPH8" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "Q8IPH8", "url": "https://www.uniprot.org/uniprotkb/Q8IPH8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q8IPH8", "url": "https://www.uniprot.org/uniprotkb/Q8IPH8" } ], "pmid": "" }, { "name": "microvillus", "id": "GO:0005902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005902", "evidence": [ { "database": "UniProtKB", "id": "Q8IPH8", "url": "https://www.uniprot.org/uniprotkb/Q8IPH8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8IPH8-1", "start_pos": "1639", "end_pos": "1639", "site_lbl": "Thr1639", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1639, "start_aa": "Thr", "end_pos": 1639, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1639", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q8IPH8-1" }, { "uniprot_canonical_ac": "Q7KUJ4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KUJ4", "url": "https://www.uniprot.org/uniprotkb/Q7KUJ4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 366, "chemical_mass": 41013.0, "gene_names": "ImpL1;CG10717;Dmel\\CG10717;Dmel_CG10717;IMP-L1;Imp-L1;ImpL1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q7KUJ4", "url": "https://www.uniprot.org/uniprotkb/Q7KUJ4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7KUJ4-1" }, { "uniprot_canonical_ac": "M9PHY7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PHY7", "url": "https://www.uniprot.org/uniprotkb/M9PHY7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1021, "chemical_mass": 111289.0, "gene_names": "Socs16D;CG8146;Dmel\\CG8146;Dmel_CG8146;SOCS16D;SOCS;Socs 16D;Socs16D;Socs16E;dmSocs16D;socs16D", "protein_name": "", "disease": [], "biological_process": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "M9PHY7", "url": "https://www.uniprot.org/uniprotkb/M9PHY7" } ], "pmid": "" }, { "name": "negative regulation of signal transduction", "id": "GO:0009968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009968", "evidence": [ { "database": "UniProtKB", "id": "M9PHY7", "url": "https://www.uniprot.org/uniprotkb/M9PHY7" } ], "pmid": "" }, { "name": "positive regulation of TORC1 signaling", "id": "GO:1904263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904263", "evidence": [ { "database": "UniProtKB", "id": "M9PHY7", "url": "https://www.uniprot.org/uniprotkb/M9PHY7" } ], "pmid": "" }, { "name": "vascular endothelial growth factor receptor signaling pathway", "id": "GO:0048010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048010", "evidence": [ { "database": "UniProtKB", "id": "M9PHY7", "url": "https://www.uniprot.org/uniprotkb/M9PHY7" } ], "pmid": "" } ], "molecular_function": [ { "name": "myosin binding", "id": "GO:0017022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017022", "evidence": [ { "database": "UniProtKB", "id": "M9PHY7", "url": "https://www.uniprot.org/uniprotkb/M9PHY7" } ], "pmid": "" }, { "name": "signaling adaptor activity", "id": "GO:0035591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035591", "evidence": [ { "database": "UniProtKB", "id": "M9PHY7", "url": "https://www.uniprot.org/uniprotkb/M9PHY7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PHY7-1" }, { "uniprot_canonical_ac": "Q8IQ63-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQ63", "url": "https://www.uniprot.org/uniprotkb/Q8IQ63" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 625, "chemical_mass": 71810.0, "gene_names": "Msr-110;CG10596;Dmel\\CG10596;Dmel_CG10596;MSR-110;Msr-110", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ63", "url": "https://www.uniprot.org/uniprotkb/Q8IQ63" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ63", "url": "https://www.uniprot.org/uniprotkb/Q8IQ63" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IQ63-1" }, { "uniprot_canonical_ac": "Q9VBK8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBK8", "url": "https://www.uniprot.org/uniprotkb/Q9VBK8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 270, "chemical_mass": 28132.0, "gene_names": "Sodq;CG5948;Dmel\\CG5948;Dmel_CG5948;SOD;Sodq", "protein_name": "superoxide dismutase", "disease": [], "molecular_function": [ { "name": "copper ion binding", "id": "GO:0005507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005507", "evidence": [ { "database": "UniProtKB", "id": "Q9VBK8", "url": "https://www.uniprot.org/uniprotkb/Q9VBK8" } ], "pmid": "" }, { "name": "superoxide dismutase activity", "id": "GO:0004784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004784", "evidence": [ { "database": "UniProtKB", "id": "Q9VBK8", "url": "https://www.uniprot.org/uniprotkb/Q9VBK8" } ], "pmid": "" }, { "name": "antioxidant activity", "id": "GO:0016209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016209", "evidence": [ { "database": "UniProtKB", "id": "Q9VBK8", "url": "https://www.uniprot.org/uniprotkb/Q9VBK8" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "Q9VBK8", "url": "https://www.uniprot.org/uniprotkb/Q9VBK8" } ], "pmid": "" } ], "biological_process": [ { "name": "superoxide metabolic process", "id": "GO:0006801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006801", "evidence": [ { "database": "UniProtKB", "id": "Q9VBK8", "url": "https://www.uniprot.org/uniprotkb/Q9VBK8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VBK8-1" }, { "uniprot_canonical_ac": "Q8IMV6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IMV6", "url": "https://www.uniprot.org/uniprotkb/Q8IMV6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 928, "chemical_mass": 102075.0, "gene_names": "Saf-B;CG6995;Dmel\\CG6995;Dmel_CG6995;LD22822;SAF-B;SAFB;Saf-B;cg6995;saf-b", "protein_name": "", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q8IMV6", "url": "https://www.uniprot.org/uniprotkb/Q8IMV6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q8IMV6", "url": "https://www.uniprot.org/uniprotkb/Q8IMV6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q8IMV6", "url": "https://www.uniprot.org/uniprotkb/Q8IMV6" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "Q8IMV6", "url": "https://www.uniprot.org/uniprotkb/Q8IMV6" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "Q8IMV6", "url": "https://www.uniprot.org/uniprotkb/Q8IMV6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IMV6-1" }, { "uniprot_canonical_ac": "Q8MLS5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8MLS5", "url": "https://www.uniprot.org/uniprotkb/Q8MLS5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 301, "chemical_mass": 35904.0, "gene_names": "CG9803;CG30412;CG9803;Dmel\\CG30412;Dmel_CG30412;anon-WO0140519.195", "protein_name": "", "disease": [], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q8MLS5", "url": "https://www.uniprot.org/uniprotkb/Q8MLS5" } ], "pmid": "" } ], "molecular_function": [ { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "Q8MLS5", "url": "https://www.uniprot.org/uniprotkb/Q8MLS5" } ], "pmid": "" } ], "biological_process": [ { "name": "protein insertion into mitochondrial inner membrane from matrix", "id": "GO:0032979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032979", "evidence": [ { "database": "UniProtKB", "id": "Q8MLS5", "url": "https://www.uniprot.org/uniprotkb/Q8MLS5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8MLS5-1" }, { "uniprot_canonical_ac": "Q9VC75-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VC75", "url": "https://www.uniprot.org/uniprotkb/Q9VC75" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 231, "chemical_mass": 26065.0, "gene_names": "Dmel\\CG13616;CG13616;Dmel\\CG13616;Dmel_CG13616", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VC75-1" }, { "uniprot_canonical_ac": "M9PHV5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PHV5", "url": "https://www.uniprot.org/uniprotkb/M9PHV5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1182, "chemical_mass": 129788.0, "gene_names": "GluRIB;CG42509;CG43743;CG4481;DGluR-IB;Dm_3L:43677;DmelGlu-R1B;Dmel\\CG43743;Dmel_CG43743;Glu-R1B;Glu-RIB;GluR1B;GluRIB;GluRIb;dglur-IB", "protein_name": "", "disease": [ { "disease_id": "DOID:0060001", "name": "withdrawal disorder", "description": "A substance-related disorder that occurs upon the abrupt discontinuation/separation or a decrease in dosage of the intake of medications, recreational drugs, and alcohol.", "url": "https://disease-ontology.org/term/DOID:0060001", "evidence": [ { "id": "0060001", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060001" } ], "weight": 0.0 }, { "disease_id": "DOID:0060823", "name": "syndromic X-linked intellectual disability 94", "description": "A syndromic X-linked intellectual disability characterized by moderate intellectual disability with variable occurrence of asthenic body habitus, dysmorphic features, autistic features, macrocephaly, seizures, myoclonic jerks, and hyporeflexia that has_material_basis_in mutation in the GRIA3 gene on chromosome Xq25.", "url": "https://disease-ontology.org/term/DOID:0060823", "evidence": [ { "id": "0060823", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060823" } ], "weight": 0.0 }, { "disease_id": "DOID:0061040", "name": "autosomal dominant intellectual developmental disorder 67", "description": "An autosomal dominant intellectual developmental disorder characterized by global developmental delay with variably impaired intellectual development apparent from infancy or early childhood that has_material_basis_in heterozygous mutation in the GRIA1 gene on chromosome 5q33.", "url": "https://disease-ontology.org/term/DOID:0061040", "evidence": [ { "id": "0061040", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061040" } ], "weight": 0.0 }, { "disease_id": "DOID:0081235", "name": "autosomal recessive intellectual developmental disorder 76", "description": "An autosomal recessive intellectual developmental disorder that has_material_basis_in homozygous mutation in the GRIA1 gene on chromosome 5q33.", "url": "https://disease-ontology.org/term/DOID:0081235", "evidence": [ { "id": "0081235", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081235" } ], "weight": 0.0 }, { "disease_id": "DOID:0081292", "name": "traumatic brain injury", "description": "A brain disease that is characterized by brain dysfunction caused by an outside force, usually a violent blow to the head.", "url": "https://disease-ontology.org/term/DOID:0081292", "evidence": [ { "id": "0081292", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081292" } ], "weight": 0.0 }, { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:13413", "name": "hepatic encephalopathy", "description": "A brain disease that is characterized by loss of brain function, the occurrence of confusion, altered level of consciousness, and coma that results when the liver is unable to remove toxins from the blood.", "url": "https://disease-ontology.org/term/DOID:13413", "evidence": [ { "id": "13413", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13413" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 }, { "disease_id": "DOID:1824", "name": "status epilepticus", "description": "", "url": "https://disease-ontology.org/term/DOID:1824", "evidence": [ { "id": "1824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1824" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:2560", "name": "morphine dependence", "description": "An opiate dependence that involves the continued use of morphine despite despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:2560", "evidence": [ { "id": "2560", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2560" } ], "weight": 0.0 }, { "disease_id": "DOID:5418", "name": "schizoaffective disorder", "description": "A psychotic disorder that is characterized by recurring episodes of mood fluctuations and a loss of contact with reality.", "url": "https://disease-ontology.org/term/DOID:5418", "evidence": [ { "id": "5418", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5418" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:670", "name": "amphetamine abuse", "description": "A substance abuse that involves the recurring use of amphetamines despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:670", "evidence": [ { "id": "670", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:670" } ], "weight": 0.0 }, { "disease_id": "DOID:809", "name": "cocaine abuse", "description": "A substance abuse that involves the recurring use of cocaine despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:809", "evidence": [ { "id": "809", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:809" } ], "weight": 0.0 }, { "disease_id": "DOID:9279", "name": "hyperhomocysteinemia", "description": "An amino acid metabolic disorder that involves an abnormally large level of homocysteine in the blood.", "url": "https://disease-ontology.org/term/DOID:9279", "evidence": [ { "id": "9279", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9279" } ], "weight": 0.0 }, { "disease_id": "DOID:9505", "name": "cannabis abuse", "description": "A substance abuse that involves the recurring use of cannabis despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:9505", "evidence": [ { "id": "9505", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9505" } ], "weight": 0.0 }, { "disease_id": "DOID:9975", "name": "cocaine dependence", "description": "A drug dependence that is a psychological dependency on the regular use of cocaine.", "url": "https://disease-ontology.org/term/DOID:9975", "evidence": [ { "id": "9975", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9975" } ], "weight": 0.0 }, { "disease_id": "DOID:9976", "name": "heroin dependence", "description": "An opiate dependence that involves the continued use of heroin despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:9976", "evidence": [ { "id": "9976", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9976" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "transmitter-gated monoatomic ion channel activity", "id": "GO:0022824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022824", "evidence": [ { "database": "UniProtKB", "id": "M9PHV5", "url": "https://www.uniprot.org/uniprotkb/M9PHV5" } ], "pmid": "" }, { "name": "extracellular ligand-gated monoatomic ion channel activity", "id": "GO:0005230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005230", "evidence": [ { "database": "UniProtKB", "id": "M9PHV5", "url": "https://www.uniprot.org/uniprotkb/M9PHV5" } ], "pmid": "" }, { "name": "transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential", "id": "GO:1904315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904315", "evidence": [ { "database": "UniProtKB", "id": "M9PHV5", "url": "https://www.uniprot.org/uniprotkb/M9PHV5" } ], "pmid": "" }, { "name": "glutamate receptor activity", "id": "GO:0008066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008066", "evidence": [ { "database": "UniProtKB", "id": "M9PHV5", "url": "https://www.uniprot.org/uniprotkb/M9PHV5" } ], "pmid": "" } ], "cellular_component": [ { "name": "ionotropic glutamate receptor complex", "id": "GO:0008328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008328", "evidence": [ { "database": "UniProtKB", "id": "M9PHV5", "url": "https://www.uniprot.org/uniprotkb/M9PHV5" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "M9PHV5", "url": "https://www.uniprot.org/uniprotkb/M9PHV5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M9PHV5", "url": "https://www.uniprot.org/uniprotkb/M9PHV5" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "M9PHV5", "url": "https://www.uniprot.org/uniprotkb/M9PHV5" } ], "pmid": "" } ], "biological_process": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "M9PHV5", "url": "https://www.uniprot.org/uniprotkb/M9PHV5" } ], "pmid": "" }, { "name": "monoatomic cation transport", "id": "GO:0006812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006812", "evidence": [ { "database": "UniProtKB", "id": "M9PHV5", "url": "https://www.uniprot.org/uniprotkb/M9PHV5" } ], "pmid": "" }, { "name": "synaptic transmission, glutamatergic", "id": "GO:0035249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035249", "evidence": [ { "database": "UniProtKB", "id": "M9PHV5", "url": "https://www.uniprot.org/uniprotkb/M9PHV5" } ], "pmid": "" }, { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "M9PHV5", "url": "https://www.uniprot.org/uniprotkb/M9PHV5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PHV5-1", "start_pos": "703", "end_pos": "703", "site_lbl": "Thr703", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 703, "start_aa": "Thr", "end_pos": 703, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr703", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9PHV5-1" }, { "uniprot_canonical_ac": "Q8IQE6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQE6", "url": "https://www.uniprot.org/uniprotkb/Q8IQE6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1076, "chemical_mass": 120321.0, "gene_names": "IRSp53;CG32082;CG7624;Dmel\\CG32082;Dmel_CG32082;IRSp53;IRS;anon-WO0118547.199", "protein_name": "", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:1094", "name": "attention deficit hyperactivity disorder", "description": "A specific developmental disorder that is characterized by co-existence of attentional problems and hyperactivity, with each behavior occurring infrequently alone and symptoms starting before seven years of age.", "url": "https://disease-ontology.org/term/DOID:1094", "evidence": [ { "id": "1094", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1094" } ], "weight": 0.0 }, { "disease_id": "DOID:11119", "name": "Gilles de la Tourette syndrome", "description": "A tic disorder that is characterized by multiple physical (motor) tics and at least one vocal (phonic) tic present for more than a year.", "url": "https://disease-ontology.org/term/DOID:11119", "evidence": [ { "id": "11119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11119" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "Q8IQE6", "url": "https://www.uniprot.org/uniprotkb/Q8IQE6" } ], "pmid": "" } ], "biological_process": [ { "name": "plasma membrane organization", "id": "GO:0007009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007009", "evidence": [ { "database": "UniProtKB", "id": "Q8IQE6", "url": "https://www.uniprot.org/uniprotkb/Q8IQE6" } ], "pmid": "" }, { "name": "filopodium assembly", "id": "GO:0046847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046847", "evidence": [ { "database": "UniProtKB", "id": "Q8IQE6", "url": "https://www.uniprot.org/uniprotkb/Q8IQE6" } ], "pmid": "" }, { "name": "membrane organization", "id": "GO:0061024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061024", "evidence": [ { "database": "UniProtKB", "id": "Q8IQE6", "url": "https://www.uniprot.org/uniprotkb/Q8IQE6" } ], "pmid": "" }, { "name": "actin filament bundle assembly", "id": "GO:0051017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051017", "evidence": [ { "database": "UniProtKB", "id": "Q8IQE6", "url": "https://www.uniprot.org/uniprotkb/Q8IQE6" } ], "pmid": "" }, { "name": "actin crosslink formation", "id": "GO:0051764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051764", "evidence": [ { "database": "UniProtKB", "id": "Q8IQE6", "url": "https://www.uniprot.org/uniprotkb/Q8IQE6" } ], "pmid": "" }, { "name": "positive regulation of actin filament polymerization", "id": "GO:0030838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030838", "evidence": [ { "database": "UniProtKB", "id": "Q8IQE6", "url": "https://www.uniprot.org/uniprotkb/Q8IQE6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q8IQE6", "url": "https://www.uniprot.org/uniprotkb/Q8IQE6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q8IQE6", "url": "https://www.uniprot.org/uniprotkb/Q8IQE6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IQE6-1" }, { "uniprot_canonical_ac": "E1JIZ4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JIZ4", "url": "https://www.uniprot.org/uniprotkb/E1JIZ4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 624, "chemical_mass": 69489.0, "gene_names": "Men-b;CG5889;Dmel\\CG5889;Dmel_CG5889;MDH;Mdh;Men-B;Men-b;anon-EST:Posey79;dME-3;dME3", "protein_name": "Malic enzyme", "disease": [], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1JIZ4", "url": "https://www.uniprot.org/uniprotkb/E1JIZ4" } ], "pmid": "" }, { "name": "NAD binding", "id": "GO:0051287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051287", "evidence": [ { "database": "UniProtKB", "id": "E1JIZ4", "url": "https://www.uniprot.org/uniprotkb/E1JIZ4" } ], "pmid": "" }, { "name": "malate dehydrogenase (decarboxylating) (NADP+) activity", "id": "GO:0004473", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004473", "evidence": [ { "database": "UniProtKB", "id": "E1JIZ4", "url": "https://www.uniprot.org/uniprotkb/E1JIZ4" } ], "pmid": "" } ], "biological_process": [ { "name": "malate metabolic process", "id": "GO:0006108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006108", "evidence": [ { "database": "UniProtKB", "id": "E1JIZ4", "url": "https://www.uniprot.org/uniprotkb/E1JIZ4" } ], "pmid": "" }, { "name": "glucose homeostasis", "id": "GO:0042593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042593", "evidence": [ { "database": "UniProtKB", "id": "E1JIZ4", "url": "https://www.uniprot.org/uniprotkb/E1JIZ4" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E1JIZ4", "url": "https://www.uniprot.org/uniprotkb/E1JIZ4" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "E1JIZ4", "url": "https://www.uniprot.org/uniprotkb/E1JIZ4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "E1JIZ4-1" }, { "uniprot_canonical_ac": "Q59DP4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q59DP4", "url": "https://www.uniprot.org/uniprotkb/Q59DP4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 663, "chemical_mass": 76448.0, "gene_names": "CG17467;anon-EST:fe2A9;2D9;BcDNA:RE73965;CG17467;CG32015;CG33521;Dmel\\CG33521;Dmel_CG33521;anon-EST:fe2A9;anon-EST:fe2D9;anon-EST:fe2E7;anon2D9", "protein_name": "LIM zinc-binding domain-containing protein", "disease": [], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q59DP4", "url": "https://www.uniprot.org/uniprotkb/Q59DP4" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q59DP4", "url": "https://www.uniprot.org/uniprotkb/Q59DP4" } ], "pmid": "" } ], "biological_process": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "Q59DP4", "url": "https://www.uniprot.org/uniprotkb/Q59DP4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q59DP4-1" }, { "uniprot_canonical_ac": "M9PD53-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PD53", "url": "https://www.uniprot.org/uniprotkb/M9PD53" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 555, "chemical_mass": 62487.0, "gene_names": "Lim3;CG10699;CG15174;Dmel\\CG10699;Dmel_CG10699;LIM3;Lim-3A;Lim3A;Lim3;l(2)37Bd;l(2)Bd;lim3", "protein_name": "", "disease": [ { "disease_id": "DOID:0061017", "name": "combined pituitary hormone deficiency 4", "description": "A combined pituitary hormone deficiency that has_material_basis_in heterozygous mutation in the LHX4 gene on chromosome 1q25.", "url": "https://disease-ontology.org/term/DOID:0061017", "evidence": [ { "id": "0061017", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061017" } ], "weight": 0.0 }, { "disease_id": "DOID:0061021", "name": "combined pituitary hormone deficiency 3", "description": "A combined pituitary hormone deficiency that has_material_basis_in homozygous mutation in the LHX3 gene on chromosome 9q34.", "url": "https://disease-ontology.org/term/DOID:0061021", "evidence": [ { "id": "0061021", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061021" } ], "weight": 0.0 }, { "disease_id": "DOID:9406", "name": "hypopituitarism", "description": "A pituitary gland disease characterized by the decreased secretion of one or more of the eight hormones normally produced by the pituitary gland.", "url": "https://disease-ontology.org/term/DOID:9406", "evidence": [ { "id": "9406", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9406" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "M9PD53", "url": "https://www.uniprot.org/uniprotkb/M9PD53" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "M9PD53", "url": "https://www.uniprot.org/uniprotkb/M9PD53" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "M9PD53", "url": "https://www.uniprot.org/uniprotkb/M9PD53" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "M9PD53", "url": "https://www.uniprot.org/uniprotkb/M9PD53" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PD53", "url": "https://www.uniprot.org/uniprotkb/M9PD53" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "M9PD53", "url": "https://www.uniprot.org/uniprotkb/M9PD53" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "M9PD53", "url": "https://www.uniprot.org/uniprotkb/M9PD53" } ], "pmid": "" }, { "name": "motor neuron axon guidance", "id": "GO:0008045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008045", "evidence": [ { "database": "UniProtKB", "id": "M9PD53", "url": "https://www.uniprot.org/uniprotkb/M9PD53" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "M9PD53", "url": "https://www.uniprot.org/uniprotkb/M9PD53" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "M9PD53", "url": "https://www.uniprot.org/uniprotkb/M9PD53" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "M9PD53", "url": "https://www.uniprot.org/uniprotkb/M9PD53" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PD53-1", "start_pos": "71", "end_pos": "71", "site_lbl": "Thr71", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 71, "start_aa": "Thr", "end_pos": 71, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr71", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9PD53-1" }, { "uniprot_canonical_ac": "M9NFC6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NFC6", "url": "https://www.uniprot.org/uniprotkb/M9NFC6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 82, "chemical_mass": 9239.0, "gene_names": "chrX_18032634_18033088.0;CG43229;Dmel\\CG43229;Dmel_CG43229;TCONS_00281284;chrX_18032634_18033088.0;lincRNA.1011", "protein_name": "TIL domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9NFC6-1" }, { "uniprot_canonical_ac": "M9PGG2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PGG2", "url": "https://www.uniprot.org/uniprotkb/M9PGG2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 938, "chemical_mass": 100828.0, "gene_names": "jim;BcDNA:SD14927;CG11352;Dmel\\CG11352;Dmel_CG11352;Jim;OVK;jim;ovfc.K;ovk", "protein_name": "", "disease": [], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "M9PGG2", "url": "https://www.uniprot.org/uniprotkb/M9PGG2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "M9PGG2", "url": "https://www.uniprot.org/uniprotkb/M9PGG2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "M9PGG2", "url": "https://www.uniprot.org/uniprotkb/M9PGG2" } ], "pmid": "" } ], "biological_process": [ { "name": "dendrite morphogenesis", "id": "GO:0048813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048813", "evidence": [ { "database": "UniProtKB", "id": "M9PGG2", "url": "https://www.uniprot.org/uniprotkb/M9PGG2" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "M9PGG2", "url": "https://www.uniprot.org/uniprotkb/M9PGG2" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "M9PGG2", "url": "https://www.uniprot.org/uniprotkb/M9PGG2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PGG2", "url": "https://www.uniprot.org/uniprotkb/M9PGG2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PGG2-1", "start_pos": "54", "end_pos": "54", "site_lbl": "Thr54", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 54, "start_aa": "Thr", "end_pos": 54, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr54", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PGG2-1", "start_pos": "792", "end_pos": "792", "site_lbl": "Thr792", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 792, "start_aa": "Thr", "end_pos": 792, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr792", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PGG2-1", "start_pos": "867", "end_pos": "867", "site_lbl": "Thr867", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 867, "start_aa": "Thr", "end_pos": 867, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr867", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9PGG2-1" }, { "uniprot_canonical_ac": "M9ND94-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9ND94", "url": "https://www.uniprot.org/uniprotkb/M9ND94" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 121, "chemical_mass": 14344.0, "gene_names": "Dmel\\CG43248;CG43248;Dmel\\CG43248;Dmel_CG43248", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9ND94-1" }, { "uniprot_canonical_ac": "Q9VAL7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VAL7", "url": "https://www.uniprot.org/uniprotkb/Q9VAL7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 605, "chemical_mass": 68019.0, "gene_names": "Cnx99A;CG11958;Cnx99A;Cnx99a;Cnx;Dmel\\CG11958;Dmel_CG11958;cnx99A;cnx", "protein_name": "", "disease": [], "molecular_function": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "Q9VAL7", "url": "https://www.uniprot.org/uniprotkb/Q9VAL7" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q9VAL7", "url": "https://www.uniprot.org/uniprotkb/Q9VAL7" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VAL7", "url": "https://www.uniprot.org/uniprotkb/Q9VAL7" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "Q9VAL7", "url": "https://www.uniprot.org/uniprotkb/Q9VAL7" } ], "pmid": "" }, { "name": "perinuclear endoplasmic reticulum", "id": "GO:0097038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097038", "evidence": [ { "database": "UniProtKB", "id": "Q9VAL7", "url": "https://www.uniprot.org/uniprotkb/Q9VAL7" } ], "pmid": "" } ], "biological_process": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "Q9VAL7", "url": "https://www.uniprot.org/uniprotkb/Q9VAL7" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "Q9VAL7", "url": "https://www.uniprot.org/uniprotkb/Q9VAL7" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "Q9VAL7", "url": "https://www.uniprot.org/uniprotkb/Q9VAL7" } ], "pmid": "" }, { "name": "regulation of calcium ion transport into cytosol", "id": "GO:0010522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010522", "evidence": [ { "database": "UniProtKB", "id": "Q9VAL7", "url": "https://www.uniprot.org/uniprotkb/Q9VAL7" } ], "pmid": "" }, { "name": "rhodopsin biosynthetic process", "id": "GO:0016063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016063", "evidence": [ { "database": "UniProtKB", "id": "Q9VAL7", "url": "https://www.uniprot.org/uniprotkb/Q9VAL7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VAL7-1" }, { "uniprot_canonical_ac": "Q8INC3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8INC3", "url": "https://www.uniprot.org/uniprotkb/Q8INC3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2194, "chemical_mass": 244841.0, "gene_names": "Mhcl;CG10218;CG10224;CG31045;DmPDZ;Dmel\\CG31045;Dmel_CG31045;MHCL(PDZ);Mhcl;Myo7A", "protein_name": "", "disease": [ { "disease_id": "DOID:0080592", "name": "Klippel-Feil syndrome 4", "description": "A Klippel-Feil syndrome that has_material_basis_in homozygous mutation in the MYO18B gene on chromosome 22q12.", "url": "https://disease-ontology.org/term/DOID:0080592", "evidence": [ { "id": "0080592", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080592" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "Q8INC3", "url": "https://www.uniprot.org/uniprotkb/Q8INC3" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "Q8INC3", "url": "https://www.uniprot.org/uniprotkb/Q8INC3" } ], "pmid": "" } ], "cellular_component": [ { "name": "sarcomere", "id": "GO:0030017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030017", "evidence": [ { "database": "UniProtKB", "id": "Q8INC3", "url": "https://www.uniprot.org/uniprotkb/Q8INC3" } ], "pmid": "" }, { "name": "myosin complex", "id": "GO:0016459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016459", "evidence": [ { "database": "UniProtKB", "id": "Q8INC3", "url": "https://www.uniprot.org/uniprotkb/Q8INC3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q8INC3", "url": "https://www.uniprot.org/uniprotkb/Q8INC3" } ], "pmid": "" }, { "name": "myosin filament", "id": "GO:0032982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032982", "evidence": [ { "database": "UniProtKB", "id": "Q8INC3", "url": "https://www.uniprot.org/uniprotkb/Q8INC3" } ], "pmid": "" }, { "name": "myosin II complex", "id": "GO:0016460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016460", "evidence": [ { "database": "UniProtKB", "id": "Q8INC3", "url": "https://www.uniprot.org/uniprotkb/Q8INC3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8INC3-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Thr194", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 194, "start_aa": "Thr", "end_pos": 194, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr194", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q8INC3-1" }, { "uniprot_canonical_ac": "Q7KVK5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KVK5", "url": "https://www.uniprot.org/uniprotkb/Q7KVK5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1298, "chemical_mass": 151902.0, "gene_names": "CG13520;CG13520;CG30275;Dmel\\CG30275;Dmel_CG30275", "protein_name": "", "disease": [ { "disease_id": "DOID:0070311", "name": "oligoasthenoteratozoospermia", "description": "A form of male infertility that is characterized by a combination of low number or oligozoospermia, poor motility or asthenozoospermia, and abnormal shape or teratozoospermia of sperms. OAT is the most common cause of male subfertility.", "url": "https://disease-ontology.org/term/DOID:0070311", "evidence": [ { "id": "0070311", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070311" } ], "weight": 0.0 }, { "disease_id": "DOID:0070583", "name": "spermatogenic failure 84", "description": "A spermatogenic failure characterized by multiple morphologic abnormalities of the sperm flagella, resulting in severely reduced motility, that has_material_basis_in homozygous or compound heterozygous mutation in the CFAP61 gene on chromosome 20p11.23.", "url": "https://disease-ontology.org/term/DOID:0070583", "evidence": [ { "id": "0070583", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070583" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "Q7KVK5", "url": "https://www.uniprot.org/uniprotkb/Q7KVK5" } ], "pmid": "" } ], "cellular_component": [ { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "Q7KVK5", "url": "https://www.uniprot.org/uniprotkb/Q7KVK5" } ], "pmid": "" } ], "biological_process": [ { "name": "sperm flagellum assembly", "id": "GO:0120316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120316", "evidence": [ { "database": "UniProtKB", "id": "Q7KVK5", "url": "https://www.uniprot.org/uniprotkb/Q7KVK5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7KVK5-1" }, { "uniprot_canonical_ac": "H9XVN1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "H9XVN1", "url": "https://www.uniprot.org/uniprotkb/H9XVN1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1256, "chemical_mass": 142888.0, "gene_names": "RhoGAP102A;BP1050;CG1748;CG34013;CG42316;Dm_4:1183;Dmel\\CG42316;Dmel_CG42316;RhoGAP102A;mlncRNA102B1;rhoGAP102A", "protein_name": "", "disease": [ { "disease_id": "DOID:10629", "name": "microphthalmia", "description": "An eye disease where one or both eyeballs are abnormally small.", "url": "https://disease-ontology.org/term/DOID:10629", "evidence": [ { "id": "10629", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10629" } ], "weight": 0.0 }, { "disease_id": "DOID:2843", "name": "long QT syndrome", "description": "An autosomal genetic disease that is characterized by delayed repolarization of the heart following a heartbeat increases the risk of episodes of torsade de pointes (TDP, a form of irregular heartbeat that originates from the ventricles).", "url": "https://disease-ontology.org/term/DOID:2843", "evidence": [ { "id": "2843", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2843" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "H9XVN1", "url": "https://www.uniprot.org/uniprotkb/H9XVN1" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "H9XVN1", "url": "https://www.uniprot.org/uniprotkb/H9XVN1" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "H9XVN1", "url": "https://www.uniprot.org/uniprotkb/H9XVN1" } ], "pmid": "" }, { "name": "positive regulation of intracellular signal transduction", "id": "GO:1902533", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902533", "evidence": [ { "database": "UniProtKB", "id": "H9XVN1", "url": "https://www.uniprot.org/uniprotkb/H9XVN1" } ], "pmid": "" } ], "cellular_component": [ { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "H9XVN1", "url": "https://www.uniprot.org/uniprotkb/H9XVN1" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "H9XVN1", "url": "https://www.uniprot.org/uniprotkb/H9XVN1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "H9XVN1-1", "start_pos": "803", "end_pos": "803", "site_lbl": "Thr803", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 803, "start_aa": "Thr", "end_pos": 803, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr803", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "H9XVN1-1" }, { "uniprot_canonical_ac": "Q0E8N3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0E8N3", "url": "https://www.uniprot.org/uniprotkb/Q0E8N3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1394, "chemical_mass": 154626.0, "gene_names": "nolo;CG13236;CG2122;CG2131;CG31619;CT6940;Dmel\\CG31619;Dmel_CG31619;nolo", "protein_name": "", "disease": [], "biological_process": [ { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "Q0E8N3", "url": "https://www.uniprot.org/uniprotkb/Q0E8N3" } ], "pmid": "" }, { "name": "ventral cord development", "id": "GO:0007419", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007419", "evidence": [ { "database": "UniProtKB", "id": "Q0E8N3", "url": "https://www.uniprot.org/uniprotkb/Q0E8N3" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q0E8N3", "url": "https://www.uniprot.org/uniprotkb/Q0E8N3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q0E8N3-1" }, { "uniprot_canonical_ac": "Q8IMV7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IMV7", "url": "https://www.uniprot.org/uniprotkb/Q8IMV7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 697, "chemical_mass": 77020.0, "gene_names": "Dmel\\CG13627;CG13627;Dmel\\CG13627;Dmel_CG13627", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q8IMV7", "url": "https://www.uniprot.org/uniprotkb/Q8IMV7" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "Q8IMV7", "url": "https://www.uniprot.org/uniprotkb/Q8IMV7" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q8IMV7", "url": "https://www.uniprot.org/uniprotkb/Q8IMV7" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "Q8IMV7", "url": "https://www.uniprot.org/uniprotkb/Q8IMV7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IMV7-1" }, { "uniprot_canonical_ac": "M9NE35-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NE35", "url": "https://www.uniprot.org/uniprotkb/M9NE35" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 645, "chemical_mass": 73120.0, "gene_names": "et;CG14225;Dmel\\CG14225;Dmel_CG14225;ET;Et;Latran;Lat;et;lat", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "M9NE35", "url": "https://www.uniprot.org/uniprotkb/M9NE35" } ], "pmid": "" } ], "molecular_function": [ { "name": "cytokine receptor activity", "id": "GO:0004896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004896", "evidence": [ { "database": "UniProtKB", "id": "M9NE35", "url": "https://www.uniprot.org/uniprotkb/M9NE35" } ], "pmid": "" }, { "name": "STAT family protein binding", "id": "GO:0097677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097677", "evidence": [ { "database": "UniProtKB", "id": "M9NE35", "url": "https://www.uniprot.org/uniprotkb/M9NE35" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "M9NE35", "url": "https://www.uniprot.org/uniprotkb/M9NE35" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "M9NE35", "url": "https://www.uniprot.org/uniprotkb/M9NE35" } ], "pmid": "" }, { "name": "protein tyrosine kinase binding", "id": "GO:1990782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990782", "evidence": [ { "database": "UniProtKB", "id": "M9NE35", "url": "https://www.uniprot.org/uniprotkb/M9NE35" } ], "pmid": "" } ], "biological_process": [ { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "M9NE35", "url": "https://www.uniprot.org/uniprotkb/M9NE35" } ], "pmid": "" }, { "name": "negative regulation of receptor signaling pathway via JAK-STAT", "id": "GO:0046426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046426", "evidence": [ { "database": "UniProtKB", "id": "M9NE35", "url": "https://www.uniprot.org/uniprotkb/M9NE35" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9NE35-1" }, { "uniprot_canonical_ac": "M9PEA2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PEA2", "url": "https://www.uniprot.org/uniprotkb/M9PEA2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 295, "chemical_mass": 30767.0, "gene_names": "CDK2AP1;CDK2AP1;CG18292;DOC1;Dmel\\CG18292;Dmel_CG18292;anon-WO03040301.144", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PEA2", "url": "https://www.uniprot.org/uniprotkb/M9PEA2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9PEA2", "url": "https://www.uniprot.org/uniprotkb/M9PEA2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "M9PEA2", "url": "https://www.uniprot.org/uniprotkb/M9PEA2" } ], "pmid": "" } ], "biological_process": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "M9PEA2", "url": "https://www.uniprot.org/uniprotkb/M9PEA2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "M9PEA2", "url": "https://www.uniprot.org/uniprotkb/M9PEA2" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA polymerase binding", "id": "GO:0070182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070182", "evidence": [ { "database": "UniProtKB", "id": "M9PEA2", "url": "https://www.uniprot.org/uniprotkb/M9PEA2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PEA2-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Thr138", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 138, "start_aa": "Thr", "end_pos": 138, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr138", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9PEA2-1" }, { "uniprot_canonical_ac": "Q9VB40-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VB40", "url": "https://www.uniprot.org/uniprotkb/Q9VB40" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1555, "chemical_mass": 170573.0, "gene_names": "CG13980;CG6599;CG13980;CG14264;CG42534;CG6599;Dmel\\CG42534;Dmel_CG42534", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VB40-1", "start_pos": "1030", "end_pos": "1030", "site_lbl": "Thr1030", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1030, "start_aa": "Thr", "end_pos": 1030, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1030", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VB40-1" }, { "uniprot_canonical_ac": "Q2PE11-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q2PE11", "url": "https://www.uniprot.org/uniprotkb/Q2PE11" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 271, "chemical_mass": 30990.0, "gene_names": "BP1023;BP1023;CG34038;Dm_2R:93795;Dm_2R:93799;Dmel\\CG34038;Dmel_CG34038", "protein_name": "DUF4773 domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q2PE11-1" }, { "uniprot_canonical_ac": "Q9VE69-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VE69", "url": "https://www.uniprot.org/uniprotkb/Q9VE69" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 663, "chemical_mass": 73478.0, "gene_names": "CG14308;CG31122;CG7687;Dmel\\CG31122;Dmel_CG31122", "protein_name": "Box A-binding factor", "disease": [ { "disease_id": "DOID:0070426", "name": "combined oxidative phosphorylation deficiency 53", "description": "A combined oxidative phosphorylation deficiency characterized by congenital-to-infantile onset, hypomyelination, microcephaly, liver dysfunction, and recurrent autoinflammation that has_material_basis_in homozygous mutation in the C2ORF69 gene on chromosome 2q33.", "url": "https://disease-ontology.org/term/DOID:0070426", "evidence": [ { "id": "0070426", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070426" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VE69", "url": "https://www.uniprot.org/uniprotkb/Q9VE69" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VE69-1" }, { "uniprot_canonical_ac": "Q8IMW9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IMW9", "url": "https://www.uniprot.org/uniprotkb/Q8IMW9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1569, "chemical_mass": 172181.0, "gene_names": "CG6454;Dmel\\CG6454;CG6454;Dmel\\CG6454;Dmel_CG6454", "protein_name": "C2 domain-containing protein", "disease": [], "molecular_function": [ { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "Q8IMW9", "url": "https://www.uniprot.org/uniprotkb/Q8IMW9" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q8IMW9", "url": "https://www.uniprot.org/uniprotkb/Q8IMW9" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q8IMW9", "url": "https://www.uniprot.org/uniprotkb/Q8IMW9" } ], "pmid": "" } ], "biological_process": [ { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "Q8IMW9", "url": "https://www.uniprot.org/uniprotkb/Q8IMW9" } ], "pmid": "" }, { "name": "positive regulation of vesicle fusion", "id": "GO:0031340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031340", "evidence": [ { "database": "UniProtKB", "id": "Q8IMW9", "url": "https://www.uniprot.org/uniprotkb/Q8IMW9" } ], "pmid": "" }, { "name": "intracellular protein transmembrane transport", "id": "GO:0065002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065002", "evidence": [ { "database": "UniProtKB", "id": "Q8IMW9", "url": "https://www.uniprot.org/uniprotkb/Q8IMW9" } ], "pmid": "" }, { "name": "positive regulation of protein targeting to membrane", "id": "GO:0090314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090314", "evidence": [ { "database": "UniProtKB", "id": "Q8IMW9", "url": "https://www.uniprot.org/uniprotkb/Q8IMW9" } ], "pmid": "" }, { "name": "positive regulation of D-glucose transmembrane transport", "id": "GO:0010828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010828", "evidence": [ { "database": "UniProtKB", "id": "Q8IMW9", "url": "https://www.uniprot.org/uniprotkb/Q8IMW9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8IMW9-1", "start_pos": "656", "end_pos": "656", "site_lbl": "Thr656", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 656, "start_aa": "Thr", "end_pos": 656, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr656", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q8IMW9-1", "start_pos": "658", "end_pos": "658", "site_lbl": "Thr658", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 658, "start_aa": "Thr", "end_pos": 658, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr658", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q8IMW9-1" }, { "uniprot_canonical_ac": "Q9VAT1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VAT1", "url": "https://www.uniprot.org/uniprotkb/Q9VAT1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1222, "chemical_mass": 136102.0, "gene_names": "Dmel\\CG1647;CG1647;Dmel\\CG1647;Dmel_CG1647", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VAT1", "url": "https://www.uniprot.org/uniprotkb/Q9VAT1" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VAT1", "url": "https://www.uniprot.org/uniprotkb/Q9VAT1" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "Q9VAT1", "url": "https://www.uniprot.org/uniprotkb/Q9VAT1" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q9VAT1", "url": "https://www.uniprot.org/uniprotkb/Q9VAT1" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "Q9VAT1", "url": "https://www.uniprot.org/uniprotkb/Q9VAT1" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q9VAT1", "url": "https://www.uniprot.org/uniprotkb/Q9VAT1" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q9VAT1", "url": "https://www.uniprot.org/uniprotkb/Q9VAT1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VAT1-1" }, { "uniprot_canonical_ac": "Q9VAJ6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VAJ6", "url": "https://www.uniprot.org/uniprotkb/Q9VAJ6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 587, "chemical_mass": 67421.0, "gene_names": "ppk20;CG7577;Dmel\\CG7577;Dmel_CG7577;PPK20;Ppk20;ppk20", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VAJ6", "url": "https://www.uniprot.org/uniprotkb/Q9VAJ6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VAJ6", "url": "https://www.uniprot.org/uniprotkb/Q9VAJ6" } ], "pmid": "" } ], "biological_process": [ { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "Q9VAJ6", "url": "https://www.uniprot.org/uniprotkb/Q9VAJ6" } ], "pmid": "" }, { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "Q9VAJ6", "url": "https://www.uniprot.org/uniprotkb/Q9VAJ6" } ], "pmid": "" } ], "molecular_function": [ { "name": "sodium channel activity", "id": "GO:0005272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005272", "evidence": [ { "database": "UniProtKB", "id": "Q9VAJ6", "url": "https://www.uniprot.org/uniprotkb/Q9VAJ6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VAJ6-1" }, { "uniprot_canonical_ac": "Q9VD87-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VD87", "url": "https://www.uniprot.org/uniprotkb/Q9VD87" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 968, "chemical_mass": 111984.0, "gene_names": "Dmel\\CG5849;CG5849;Dmel\\CG5849;Dmel_CG5849", "protein_name": "Aminopeptidase", "disease": [ { "disease_id": "DOID:13129", "name": "severe pre-eclampsia", "description": "A pre-eclampsia that has_symptom at least one of the following: SBP of 160mm HG or higher or DPB of 110mm HG or higher on 2 occasions at least 6 hours apart, proteinuria more than 5g in a 24-hour collection, pulmonary edema or cyanosis, oliguria, persistent headaches, epigastric pain and/or impaired liver function, thrombocytopenia, oligohydramnios, decreased fetal growth or placental abruption.", "url": "https://disease-ontology.org/term/DOID:13129", "evidence": [ { "id": "13129", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13129" } ], "weight": 0.0 }, { "disease_id": "DOID:2871", "name": "endometrial carcinoma", "description": "A endometrial cancer that is located_in the tissue lining the uterus.", "url": "https://disease-ontology.org/term/DOID:2871", "evidence": [ { "id": "2871", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2871" } ], "weight": 0.0 }, { "disease_id": "DOID:2893", "name": "cervix carcinoma", "description": "A cervical cancer that is located_in the cervix uteri or located_in the cervical area and that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:2893", "evidence": [ { "id": "2893", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2893" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VD87", "url": "https://www.uniprot.org/uniprotkb/Q9VD87" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "Q9VD87", "url": "https://www.uniprot.org/uniprotkb/Q9VD87" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VD87", "url": "https://www.uniprot.org/uniprotkb/Q9VD87" } ], "pmid": "" } ], "molecular_function": [ { "name": "metallopeptidase activity", "id": "GO:0008237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008237", "evidence": [ { "database": "UniProtKB", "id": "Q9VD87", "url": "https://www.uniprot.org/uniprotkb/Q9VD87" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VD87", "url": "https://www.uniprot.org/uniprotkb/Q9VD87" } ], "pmid": "" }, { "name": "aminopeptidase activity", "id": "GO:0004177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004177", "evidence": [ { "database": "UniProtKB", "id": "Q9VD87", "url": "https://www.uniprot.org/uniprotkb/Q9VD87" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VD87-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Thr3", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3, "start_aa": "Thr", "end_pos": 3, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VD87-1" }, { "uniprot_canonical_ac": "Q9VIR9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VIR9", "url": "https://www.uniprot.org/uniprotkb/Q9VIR9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 367, "chemical_mass": 41507.0, "gene_names": "fs(2)ltoPP43;BEST:LD12957;CG10528;Dmel\\CG10528;Dmel_CG10528;LD12957;fs(2)ltoPP43;l(2)38Ac", "protein_name": "Probable RNA polymerase II nuclear localization protein SLC7A6OS", "disease": [ { "disease_id": "DOID:891", "name": "progressive myoclonus epilepsy", "description": "A variable age at onset electroclinical syndrome characterized by a relentlessly progressive disease course until death.", "url": "https://disease-ontology.org/term/DOID:891", "evidence": [ { "id": "891", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:891" } ], "weight": 0.0 } ], "biological_process": [ { "name": "chorion-containing eggshell formation", "id": "GO:0007304", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007304", "evidence": [ { "database": "UniProtKB", "id": "Q9VIR9", "url": "https://www.uniprot.org/uniprotkb/Q9VIR9" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q9VIR9", "url": "https://www.uniprot.org/uniprotkb/Q9VIR9" } ], "pmid": "" }, { "name": "developmental process", "id": "GO:0032502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032502", "evidence": [ { "database": "UniProtKB", "id": "Q9VIR9", "url": "https://www.uniprot.org/uniprotkb/Q9VIR9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VIR9", "url": "https://www.uniprot.org/uniprotkb/Q9VIR9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VIR9", "url": "https://www.uniprot.org/uniprotkb/Q9VIR9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VIR9-1" }, { "uniprot_canonical_ac": "Q7KW09-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KW09", "url": "https://www.uniprot.org/uniprotkb/Q7KW09" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1030, "chemical_mass": 114277.0, "gene_names": "Gcna;CG14814;Dmel\\CG14814;Dmel_CG14814;EG:63B12.6;Gcna", "protein_name": "Germ cell nuclear acidic protein", "disease": [ { "disease_id": "DOID:0070595", "name": "X-linked spermatogenic failure 4", "description": "A spermatogenic failure characterized by azoospermia or oligoasthenoteratozoospermia that has_material_basis_in hemizygous mutation in the GCNA gene on chromosome Xq13.1.", "url": "https://disease-ontology.org/term/DOID:0070595", "evidence": [ { "id": "0070595", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070595" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q7KW09", "url": "https://www.uniprot.org/uniprotkb/Q7KW09" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q7KW09", "url": "https://www.uniprot.org/uniprotkb/Q7KW09" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "Q7KW09", "url": "https://www.uniprot.org/uniprotkb/Q7KW09" } ], "pmid": "" }, { "name": "P granule", "id": "GO:0043186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043186", "evidence": [ { "database": "UniProtKB", "id": "Q7KW09", "url": "https://www.uniprot.org/uniprotkb/Q7KW09" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA topoisomerase binding", "id": "GO:0044547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044547", "evidence": [ { "database": "UniProtKB", "id": "Q7KW09", "url": "https://www.uniprot.org/uniprotkb/Q7KW09" } ], "pmid": "" }, { "name": "MCM complex binding", "id": "GO:1904931", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904931", "evidence": [ { "database": "UniProtKB", "id": "Q7KW09", "url": "https://www.uniprot.org/uniprotkb/Q7KW09" } ], "pmid": "" } ], "biological_process": [ { "name": "protein-DNA covalent cross-linking repair", "id": "GO:0106300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106300", "evidence": [ { "database": "UniProtKB", "id": "Q7KW09", "url": "https://www.uniprot.org/uniprotkb/Q7KW09" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "Q7KW09", "url": "https://www.uniprot.org/uniprotkb/Q7KW09" } ], "pmid": "" }, { "name": "positive regulation of DNA repair", "id": "GO:0045739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045739", "evidence": [ { "database": "UniProtKB", "id": "Q7KW09", "url": "https://www.uniprot.org/uniprotkb/Q7KW09" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7KW09-1" }, { "uniprot_canonical_ac": "A8Y5A2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8Y5A2", "url": "https://www.uniprot.org/uniprotkb/A8Y5A2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 441, "chemical_mass": 50023.0, "gene_names": "Dmel\\CG12061;CG12061;CG40148;Dmel\\CG12061;Dmel_CG12061", "protein_name": "Sodium/calcium exchanger membrane region domain-containing protein", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A8Y5A2", "url": "https://www.uniprot.org/uniprotkb/A8Y5A2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A8Y5A2", "url": "https://www.uniprot.org/uniprotkb/A8Y5A2" } ], "pmid": "" } ], "biological_process": [ { "name": "calcium ion transport", "id": "GO:0006816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006816", "evidence": [ { "database": "UniProtKB", "id": "A8Y5A2", "url": "https://www.uniprot.org/uniprotkb/A8Y5A2" } ], "pmid": "" }, { "name": "intracellular calcium ion homeostasis", "id": "GO:0006874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "database": "UniProtKB", "id": "A8Y5A2", "url": "https://www.uniprot.org/uniprotkb/A8Y5A2" } ], "pmid": "" }, { "name": "calcium ion transmembrane transport", "id": "GO:0070588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070588", "evidence": [ { "database": "UniProtKB", "id": "A8Y5A2", "url": "https://www.uniprot.org/uniprotkb/A8Y5A2" } ], "pmid": "" } ], "molecular_function": [ { "name": "antiporter activity", "id": "GO:0015297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015297", "evidence": [ { "database": "UniProtKB", "id": "A8Y5A2", "url": "https://www.uniprot.org/uniprotkb/A8Y5A2" } ], "pmid": "" }, { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "A8Y5A2", "url": "https://www.uniprot.org/uniprotkb/A8Y5A2" } ], "pmid": "" }, { "name": "calcium, potassium:sodium antiporter activity", "id": "GO:0008273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008273", "evidence": [ { "database": "UniProtKB", "id": "A8Y5A2", "url": "https://www.uniprot.org/uniprotkb/A8Y5A2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8Y5A2-1" }, { "uniprot_canonical_ac": "M9PGQ5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PGQ5", "url": "https://www.uniprot.org/uniprotkb/M9PGQ5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1499, "chemical_mass": 166061.0, "gene_names": "CG9137;Dmel\\CG32333;CG32333;CG9137;CG9146;Dmel\\CG32333;Dmel_CG32333;cg32333", "protein_name": "DUF676 domain-containing protein", "disease": [], "biological_process": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "M9PGQ5", "url": "https://www.uniprot.org/uniprotkb/M9PGQ5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PGQ5-1" }, { "uniprot_canonical_ac": "M9NDP9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NDP9", "url": "https://www.uniprot.org/uniprotkb/M9NDP9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 196, "chemical_mass": 22602.0, "gene_names": "Dmel\\CG15278;NEST:bs32h08;CG15278;Dmel\\CG15278;Dmel_CG15278;NEST:bs32h08;bs32h08.y1", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9NDP9-1" }, { "uniprot_canonical_ac": "A8JUS7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JUS7", "url": "https://www.uniprot.org/uniprotkb/A8JUS7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 990, "chemical_mass": 112143.0, "gene_names": "Dmel\\CG17707;CG17707;Dmel\\CG17707;Dmel_CG17707;EG:23E12.3", "protein_name": "Nose resistant-to-fluoxetine protein N-terminal domain-containing protein", "disease": [], "molecular_function": [ { "name": "acyltransferase activity, transferring groups other than amino-acyl groups", "id": "GO:0016747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016747", "evidence": [ { "database": "UniProtKB", "id": "A8JUS7", "url": "https://www.uniprot.org/uniprotkb/A8JUS7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8JUS7-1" }, { "uniprot_canonical_ac": "Q5LJX8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q5LJX8", "url": "https://www.uniprot.org/uniprotkb/Q5LJX8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 542, "chemical_mass": 58408.0, "gene_names": "zyd;BEST:CK02262;CG2893;CG40147;CK02262;Dmel\\CG2893;Dmel_CG2893;Nckx-x;Ncxk-x;zyd", "protein_name": "", "disease": [ { "disease_id": "DOID:0110063", "name": "amelogenesis imperfecta hypomaturation type 2A5", "description": "An amelogenesis imperfecta that has_material_basis_in homozygous mutation in the SLC24A4 gene on chromosome 14q32.", "url": "https://disease-ontology.org/term/DOID:0110063", "evidence": [ { "id": "0110063", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110063" } ], "weight": 0.0 }, { "disease_id": "DOID:10123", "name": "pigmentation disease", "description": "A skin disease that is characterized by discoloration of the skin.", "url": "https://disease-ontology.org/term/DOID:10123", "evidence": [ { "id": "10123", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10123" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q5LJX8", "url": "https://www.uniprot.org/uniprotkb/Q5LJX8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5LJX8", "url": "https://www.uniprot.org/uniprotkb/Q5LJX8" } ], "pmid": "" } ], "biological_process": [ { "name": "calcium ion transport", "id": "GO:0006816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006816", "evidence": [ { "database": "UniProtKB", "id": "Q5LJX8", "url": "https://www.uniprot.org/uniprotkb/Q5LJX8" } ], "pmid": "" }, { "name": "potassium ion transport", "id": "GO:0006813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006813", "evidence": [ { "database": "UniProtKB", "id": "Q5LJX8", "url": "https://www.uniprot.org/uniprotkb/Q5LJX8" } ], "pmid": "" }, { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "Q5LJX8", "url": "https://www.uniprot.org/uniprotkb/Q5LJX8" } ], "pmid": "" }, { "name": "calcium-mediated signaling", "id": "GO:0019722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019722", "evidence": [ { "database": "UniProtKB", "id": "Q5LJX8", "url": "https://www.uniprot.org/uniprotkb/Q5LJX8" } ], "pmid": "" }, { "name": "intracellular calcium ion homeostasis", "id": "GO:0006874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "database": "UniProtKB", "id": "Q5LJX8", "url": "https://www.uniprot.org/uniprotkb/Q5LJX8" } ], "pmid": "" }, { "name": "calcium ion transmembrane transport", "id": "GO:0070588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070588", "evidence": [ { "database": "UniProtKB", "id": "Q5LJX8", "url": "https://www.uniprot.org/uniprotkb/Q5LJX8" } ], "pmid": "" } ], "molecular_function": [ { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "Q5LJX8", "url": "https://www.uniprot.org/uniprotkb/Q5LJX8" } ], "pmid": "" }, { "name": "antiporter activity", "id": "GO:0015297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015297", "evidence": [ { "database": "UniProtKB", "id": "Q5LJX8", "url": "https://www.uniprot.org/uniprotkb/Q5LJX8" } ], "pmid": "" }, { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "Q5LJX8", "url": "https://www.uniprot.org/uniprotkb/Q5LJX8" } ], "pmid": "" }, { "name": "calcium, potassium:sodium antiporter activity", "id": "GO:0008273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008273", "evidence": [ { "database": "UniProtKB", "id": "Q5LJX8", "url": "https://www.uniprot.org/uniprotkb/Q5LJX8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q5LJX8-1", "start_pos": "158", "end_pos": "158", "site_lbl": "Thr158", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 158, "start_aa": "Thr", "end_pos": 158, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr158", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q5LJX8-1" }, { "uniprot_canonical_ac": "Q9VAJ0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VAJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VAJ0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 254, "chemical_mass": 28582.0, "gene_names": "Dmel\\CG7582;CG7582;Dmel\\CG7582;Dmel_CG7582", "protein_name": "lysoplasmalogenase", "disease": [], "molecular_function": [ { "name": "alkenylglycerophosphocholine hydrolase activity", "id": "GO:0047408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047408", "evidence": [ { "database": "UniProtKB", "id": "Q9VAJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VAJ0" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q9VAJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VAJ0" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VAJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VAJ0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VAJ0-1" }, { "uniprot_canonical_ac": "Q3KN41-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1840, "chemical_mass": 199615.0, "gene_names": "Nrx-1;CG7050;CT21808;DNrx;Dmel\\CG7050;Dmel_CG7050;Dnrx;Nrx-1;Nrx-I;Nrx1;Nrx;dNRXN3;dNrx;dnrx-1;dnrx1;dnrx;neurexin;nrx-1;nrx1;nrx", "protein_name": "Neurexin 1", "disease": [ { "disease_id": "DOID:0050741", "name": "alcohol dependence", "description": "A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.", "url": "https://disease-ontology.org/term/DOID:0050741", "evidence": [ { "id": "0050741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050741" } ], "weight": 0.0 }, { "disease_id": "DOID:0050742", "name": "nicotine dependence", "description": "A substance dependence that is characterized by a physical dependence on nicotine.", "url": "https://disease-ontology.org/term/DOID:0050742", "evidence": [ { "id": "0050742", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050742" } ], "weight": 0.0 }, { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0111332", "name": "Pitt-Hopkins-like syndrome 2", "description": "A syndromic intellectual disability characterized by developmental delay and intellectual disability with many patients also displaying infantile hypotonia and autistic features that has_material_basis_in compound heterozygous or homozygous mutation in the NRXN1 gene on chromosome 2p16.3.", "url": "https://disease-ontology.org/term/DOID:0111332", "evidence": [ { "id": "0111332", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111332" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 } ], "biological_process": [ { "name": "neuromuscular synaptic transmission", "id": "GO:0007274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007274", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "associative learning", "id": "GO:0008306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008306", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "synapse organization", "id": "GO:0050808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050808", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "synaptic assembly at neuromuscular junction", "id": "GO:0051124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051124", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "synapse assembly", "id": "GO:0007416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007416", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "locomotion", "id": "GO:0040011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040011", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "synaptic vesicle endocytosis", "id": "GO:0048488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048488", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "neuroligin clustering involved in postsynaptic membrane assembly", "id": "GO:0097118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097118", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "vitamin A transport", "id": "GO:0071938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071938", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "gephyrin clustering involved in postsynaptic density assembly", "id": "GO:0097116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097116", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "learning", "id": "GO:0007612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007612", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "adult behavior", "id": "GO:0030534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030534", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "terminal button organization", "id": "GO:0072553", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072553", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "regulation of terminal button organization", "id": "GO:2000331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000331", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "presynaptic membrane assembly", "id": "GO:0097105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097105", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" } ], "cellular_component": [ { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "terminal bouton", "id": "GO:0043195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043195", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "type I terminal bouton", "id": "GO:0061174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061174", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "trans-synaptic protein complex", "id": "GO:0098820", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098820", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "presynaptic active zone membrane", "id": "GO:0048787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048787", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" } ], "molecular_function": [ { "name": "apolipoprotein binding", "id": "GO:0034185", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034185", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "neuroligin family protein binding", "id": "GO:0097109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097109", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "neurexin family protein binding", "id": "GO:0042043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042043", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "Q3KN41", "url": "https://www.uniprot.org/uniprotkb/Q3KN41" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q3KN41-1", "start_pos": "1538", "end_pos": "1538", "site_lbl": "Thr1538", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1538, "start_aa": "Thr", "end_pos": 1538, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1538", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q3KN41-1", "start_pos": "1559", "end_pos": "1559", "site_lbl": "Thr1559", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1559, "start_aa": "Thr", "end_pos": 1559, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1559", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q3KN41-1", "start_pos": "777", "end_pos": "777", "site_lbl": "Thr777", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 777, "start_aa": "Thr", "end_pos": 777, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr777", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q3KN41-1" }, { "uniprot_canonical_ac": "Q8IN20-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IN20", "url": "https://www.uniprot.org/uniprotkb/Q8IN20" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 203, "chemical_mass": 23859.0, "gene_names": "BcDNA:SD11171;Dmel\\CG31174;BcDNA:SD11171;CG31174;Dmel\\CG31174;Dmel_CG31174", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IN20-1" }, { "uniprot_canonical_ac": "Q9VB82-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VB82", "url": "https://www.uniprot.org/uniprotkb/Q9VB82" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 366, "chemical_mass": 40040.0, "gene_names": "Cpr97Ea;CG6131;Cpr97Ea;Dmel\\CG6131;Dmel_CG6131", "protein_name": "", "disease": [], "molecular_function": [ { "name": "structural constituent of chitin-based larval cuticle", "id": "GO:0008010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008010", "evidence": [ { "database": "UniProtKB", "id": "Q9VB82", "url": "https://www.uniprot.org/uniprotkb/Q9VB82" } ], "pmid": "" } ], "biological_process": [ { "name": "chitin-based cuticle development", "id": "GO:0040003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040003", "evidence": [ { "database": "UniProtKB", "id": "Q9VB82", "url": "https://www.uniprot.org/uniprotkb/Q9VB82" } ], "pmid": "" } ], "cellular_component": [ { "name": "chitin-based extracellular matrix", "id": "GO:0062129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062129", "evidence": [ { "database": "UniProtKB", "id": "Q9VB82", "url": "https://www.uniprot.org/uniprotkb/Q9VB82" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VB82-1" }, { "uniprot_canonical_ac": "Q8MLN2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8MLN2", "url": "https://www.uniprot.org/uniprotkb/Q8MLN2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 263, "chemical_mass": 30019.0, "gene_names": "BcDNA:SD21514;BcDNA:SD21514;CG30428;Dmel\\CG30428;Dmel_CG30428", "protein_name": "Regulatory protein zeste", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q8MLN2", "url": "https://www.uniprot.org/uniprotkb/Q8MLN2" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q8MLN2", "url": "https://www.uniprot.org/uniprotkb/Q8MLN2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q8MLN2", "url": "https://www.uniprot.org/uniprotkb/Q8MLN2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8MLN2-1" }, { "uniprot_canonical_ac": "Q9V9P5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V9P5", "url": "https://www.uniprot.org/uniprotkb/Q9V9P5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 731, "chemical_mass": 83282.0, "gene_names": "Dmel\\CG2528;lincRNA.224;CG2528;Dmel\\CG2528;Dmel_CG2528;lincRNA.224", "protein_name": "Prolyl endopeptidase", "disease": [ { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "Q9V9P5", "url": "https://www.uniprot.org/uniprotkb/Q9V9P5" } ], "pmid": "" }, { "name": "serine hydrolase activity", "id": "GO:0017171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017171", "evidence": [ { "database": "UniProtKB", "id": "Q9V9P5", "url": "https://www.uniprot.org/uniprotkb/Q9V9P5" } ], "pmid": "" }, { "name": "oligopeptidase activity", "id": "GO:0070012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070012", "evidence": [ { "database": "UniProtKB", "id": "Q9V9P5", "url": "https://www.uniprot.org/uniprotkb/Q9V9P5" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9V9P5", "url": "https://www.uniprot.org/uniprotkb/Q9V9P5" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9V9P5", "url": "https://www.uniprot.org/uniprotkb/Q9V9P5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V9P5-1" }, { "uniprot_canonical_ac": "A8JRF1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JRF1", "url": "https://www.uniprot.org/uniprotkb/A8JRF1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 288, "chemical_mass": 32058.0, "gene_names": "Dmel\\CG34295;CG34295;Dmel\\CG34295;Dmel_CG34295;SPH253", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A8JRF1", "url": "https://www.uniprot.org/uniprotkb/A8JRF1" } ], "pmid": "" } ], "molecular_function": [ { "name": "serine-type peptidase activity", "id": "GO:0008236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008236", "evidence": [ { "database": "UniProtKB", "id": "A8JRF1", "url": "https://www.uniprot.org/uniprotkb/A8JRF1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8JRF1-1" }, { "uniprot_canonical_ac": "A8JRG8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JRG8", "url": "https://www.uniprot.org/uniprotkb/A8JRG8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 111, "chemical_mass": 12517.0, "gene_names": "Rpp14a;CG34317;Dmel\\CG34317;Dmel_CG34317;Dromel_CG7950_FBtr0085563_CHCHD4inmorf_uORF;Pop8;Rpp14a;Rpp14;dMia40", "protein_name": "", "disease": [], "cellular_component": [ { "name": "multimeric ribonuclease P complex", "id": "GO:0030681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030681", "evidence": [ { "database": "UniProtKB", "id": "A8JRG8", "url": "https://www.uniprot.org/uniprotkb/A8JRG8" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A8JRG8", "url": "https://www.uniprot.org/uniprotkb/A8JRG8" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A8JRG8", "url": "https://www.uniprot.org/uniprotkb/A8JRG8" } ], "pmid": "" } ], "biological_process": [ { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "A8JRG8", "url": "https://www.uniprot.org/uniprotkb/A8JRG8" } ], "pmid": "" }, { "name": "tRNA 5'-leader removal", "id": "GO:0001682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001682", "evidence": [ { "database": "UniProtKB", "id": "A8JRG8", "url": "https://www.uniprot.org/uniprotkb/A8JRG8" } ], "pmid": "" } ], "molecular_function": [ { "name": "ribonuclease P activity", "id": "GO:0004526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004526", "evidence": [ { "database": "UniProtKB", "id": "A8JRG8", "url": "https://www.uniprot.org/uniprotkb/A8JRG8" } ], "pmid": "" }, { "name": "ribonuclease P RNA binding", "id": "GO:0033204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033204", "evidence": [ { "database": "UniProtKB", "id": "A8JRG8", "url": "https://www.uniprot.org/uniprotkb/A8JRG8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8JRG8-1" }, { "uniprot_canonical_ac": "A8JUV4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JUV4", "url": "https://www.uniprot.org/uniprotkb/A8JUV4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 578, "chemical_mass": 56116.0, "gene_names": "Vml;CG34333;CRM-80;Dmel\\CG34333;Vml;vml", "protein_name": "Vitelline membrane-like protein", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A8JUV4", "url": "https://www.uniprot.org/uniprotkb/A8JUV4" } ], "pmid": "" }, { "name": "egg coat", "id": "GO:0035805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035805", "evidence": [ { "database": "UniProtKB", "id": "A8JUV4", "url": "https://www.uniprot.org/uniprotkb/A8JUV4" } ], "pmid": "" }, { "name": "vitelline envelope", "id": "GO:0060388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060388", "evidence": [ { "database": "UniProtKB", "id": "A8JUV4", "url": "https://www.uniprot.org/uniprotkb/A8JUV4" } ], "pmid": "" } ], "biological_process": [ { "name": "dorsal/ventral axis specification", "id": "GO:0009950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009950", "evidence": [ { "database": "UniProtKB", "id": "A8JUV4", "url": "https://www.uniprot.org/uniprotkb/A8JUV4" } ], "pmid": "" }, { "name": "vitelline membrane formation involved in chorion-containing eggshell formation", "id": "GO:0007305", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007305", "evidence": [ { "database": "UniProtKB", "id": "A8JUV4", "url": "https://www.uniprot.org/uniprotkb/A8JUV4" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of vitelline membrane", "id": "GO:0008316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008316", "evidence": [ { "database": "UniProtKB", "id": "A8JUV4", "url": "https://www.uniprot.org/uniprotkb/A8JUV4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8JUV4-1" }, { "uniprot_canonical_ac": "A8JV15-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JV15", "url": "https://www.uniprot.org/uniprotkb/A8JV15" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 110, "chemical_mass": 12736.0, "gene_names": "Dmel\\CG34338;CG34338;Dmel\\CG34338;Dmel_CG34338;FBgn0085367", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8JV15-1" }, { "uniprot_canonical_ac": "A8JV30-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JV30", "url": "https://www.uniprot.org/uniprotkb/A8JV30" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 220, "chemical_mass": 20007.0, "gene_names": "Dmel\\CG34327;CG34327;Dmel\\CG34327;Dmel_CG34327", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8JV30-1" }, { "uniprot_canonical_ac": "A8QI20-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8QI20", "url": "https://www.uniprot.org/uniprotkb/A8QI20" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 439, "chemical_mass": 50687.0, "gene_names": "Dmel\\CG41561;CG41561;Dmel\\CG41561;Dmel_CG41561", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8QI20-1" }, { "uniprot_canonical_ac": "A8Y5B0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8Y5B0", "url": "https://www.uniprot.org/uniprotkb/A8Y5B0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 436, "chemical_mass": 49953.0, "gene_names": "FBgn0058460;CG17159;CG40460;Dmel\\CG17159;Dmel_CG17159;FBgn0039945;FBgn0058460;anon-20Ea", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "A8Y5B0-1" }, { "uniprot_canonical_ac": "B7YZW2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7YZW2", "url": "https://www.uniprot.org/uniprotkb/B7YZW2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 242, "chemical_mass": 27644.0, "gene_names": "Hyls1;CG42231;Dmel\\CG42231;Dmel_CG42231;HYLS1;Hyls1;hyls1", "protein_name": "", "disease": [ { "disease_id": "DOID:0050779", "name": "hydrolethalus syndrome", "description": "A syndrome characterized by multiple fetal developmental defects including polydactyly and central nervous system malformations that results from a single amino acid mutation of D211G of the HYLS1 gene which plays a central role in cilia formation.", "url": "https://disease-ontology.org/term/DOID:0050779", "evidence": [ { "id": "0050779", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050779" } ], "weight": 0.0 }, { "disease_id": "DOID:0111355", "name": "hydrolethalus syndrome 1", "description": "A hydrolethalus syndrome that has_material_basis_in homozygous or compound heterozygous mutation in the HYLS1 gene on chromosome 11q24.2.", "url": "https://disease-ontology.org/term/DOID:0111355", "evidence": [ { "id": "0111355", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111355" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "B7YZW2", "url": "https://www.uniprot.org/uniprotkb/B7YZW2" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "B7YZW2", "url": "https://www.uniprot.org/uniprotkb/B7YZW2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "B7YZW2-1" }, { "uniprot_canonical_ac": "B7YZX3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7YZX3", "url": "https://www.uniprot.org/uniprotkb/B7YZX3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 48, "chemical_mass": 5150.0, "gene_names": "Dmel\\CG42305;CG42305;Dmel\\CG42305;Dmel_CG42305;Dromel_CG17325_FBtr0081102_uORF", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "B7YZX3-1" }, { "uniprot_canonical_ac": "B7YZX7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7YZX7", "url": "https://www.uniprot.org/uniprotkb/B7YZX7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 148, "chemical_mass": 15430.0, "gene_names": "CG9266;Dmel\\CG42238;CG42238;CG9266;Dmel\\CG42238;Dmel_CG42238", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "B7YZX7-1" }, { "uniprot_canonical_ac": "Q9VIK7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VIK7", "url": "https://www.uniprot.org/uniprotkb/Q9VIK7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1417, "chemical_mass": 154525.0, "gene_names": "CG17465;38D.30;CG17465;CG17466;CG31678;Dmel\\CG31678;Dmel_CG31678", "protein_name": "SUN domain-containing protein", "disease": [ { "disease_id": "DOID:0110344", "name": "osteogenesis imperfecta type 5", "description": "An osteogenesis imperfecta that has_material_basis_in mutation in the IFITM5 gene on chromosome 11p15.", "url": "https://disease-ontology.org/term/DOID:0110344", "evidence": [ { "id": "0110344", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110344" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VIK7", "url": "https://www.uniprot.org/uniprotkb/Q9VIK7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VIK7", "url": "https://www.uniprot.org/uniprotkb/Q9VIK7" } ], "pmid": "" }, { "name": "rough endoplasmic reticulum", "id": "GO:0005791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005791", "evidence": [ { "database": "UniProtKB", "id": "Q9VIK7", "url": "https://www.uniprot.org/uniprotkb/Q9VIK7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VIK7", "url": "https://www.uniprot.org/uniprotkb/Q9VIK7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VIK7-1" }, { "uniprot_canonical_ac": "B7Z016-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7Z016", "url": "https://www.uniprot.org/uniprotkb/B7Z016" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 75, "chemical_mass": 8262.0, "gene_names": "CG10039;CG10039;CG43773;Dmel\\CG43773;Dmel_CG43773", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "B7Z016-1" }, { "uniprot_canonical_ac": "B7Z085-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7Z085", "url": "https://www.uniprot.org/uniprotkb/B7Z085" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 162, "chemical_mass": 18875.0, "gene_names": "Dmel\\CG42263;CG42263;Dmel\\CG42263;Dmel_CG42263", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "B7Z085-1" }, { "uniprot_canonical_ac": "B7Z0C9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7Z0C9", "url": "https://www.uniprot.org/uniprotkb/B7Z0C9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 95, "chemical_mass": 10998.0, "gene_names": "Dmel\\CG42307;CG42307;Dmel\\CG42307;Dmel_CG42307", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "B7Z0C9-1" }, { "uniprot_canonical_ac": "B7Z0I1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7Z0I1", "url": "https://www.uniprot.org/uniprotkb/B7Z0I1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 422, "chemical_mass": 50151.0, "gene_names": "Grl62b;CG32308;CG42356;Dmel\\CG42356;Dmel_CG42356;Grl62b", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "B7Z0I1", "url": "https://www.uniprot.org/uniprotkb/B7Z0I1" } ], "pmid": "" } ], "biological_process": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "B7Z0I1", "url": "https://www.uniprot.org/uniprotkb/B7Z0I1" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated channel activity", "id": "GO:0022834", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022834", "evidence": [ { "database": "UniProtKB", "id": "B7Z0I1", "url": "https://www.uniprot.org/uniprotkb/B7Z0I1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "B7Z0I1-1" }, { "uniprot_canonical_ac": "Q9VFU8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VFU8", "url": "https://www.uniprot.org/uniprotkb/Q9VFU8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 972, "chemical_mass": 105234.0, "gene_names": "yrt;CG9764;Dmel\\CG9764;Dmel_CG9764;Nbl4;Yrt;Yurt;dlhB;l(3)87Ek;l(3)E19;l(3)m112;m112;yrt", "protein_name": "Moesin/ezrin/radixin homolog 1", "disease": [ { "disease_id": "DOID:576", "name": "proteinuria", "description": "A kidney disease that is characterized by the presence of excess proteins in the urine.", "url": "https://disease-ontology.org/term/DOID:576", "evidence": [ { "id": "576", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:576" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VFU8", "url": "https://www.uniprot.org/uniprotkb/Q9VFU8" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "Q9VFU8", "url": "https://www.uniprot.org/uniprotkb/Q9VFU8" } ], "pmid": "" }, { "name": "zonula adherens", "id": "GO:0005915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005915", "evidence": [ { "database": "UniProtKB", "id": "Q9VFU8", "url": "https://www.uniprot.org/uniprotkb/Q9VFU8" } ], "pmid": "" }, { "name": "rhabdomere", "id": "GO:0016028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016028", "evidence": [ { "database": "UniProtKB", "id": "Q9VFU8", "url": "https://www.uniprot.org/uniprotkb/Q9VFU8" } ], "pmid": "" }, { "name": "septate junction", "id": "GO:0005918", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005918", "evidence": [ { "database": "UniProtKB", "id": "Q9VFU8", "url": "https://www.uniprot.org/uniprotkb/Q9VFU8" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "Q9VFU8", "url": "https://www.uniprot.org/uniprotkb/Q9VFU8" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "Q9VFU8", "url": "https://www.uniprot.org/uniprotkb/Q9VFU8" } ], "pmid": "" } ], "biological_process": [ { "name": "establishment of epithelial cell apical/basal polarity", "id": "GO:0045198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045198", "evidence": [ { "database": "UniProtKB", "id": "Q9VFU8", "url": "https://www.uniprot.org/uniprotkb/Q9VFU8" } ], "pmid": "" }, { "name": "eye photoreceptor cell development", "id": "GO:0042462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042462", "evidence": [ { "database": "UniProtKB", "id": "Q9VFU8", "url": "https://www.uniprot.org/uniprotkb/Q9VFU8" } ], "pmid": "" }, { "name": "establishment or maintenance of apical/basal cell polarity", "id": "GO:0035088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035088", "evidence": [ { "database": "UniProtKB", "id": "Q9VFU8", "url": "https://www.uniprot.org/uniprotkb/Q9VFU8" } ], "pmid": "" }, { "name": "germ-band shortening", "id": "GO:0007390", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007390", "evidence": [ { "database": "UniProtKB", "id": "Q9VFU8", "url": "https://www.uniprot.org/uniprotkb/Q9VFU8" } ], "pmid": "" }, { "name": "dorsal closure", "id": "GO:0007391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007391", "evidence": [ { "database": "UniProtKB", "id": "Q9VFU8", "url": "https://www.uniprot.org/uniprotkb/Q9VFU8" } ], "pmid": "" }, { "name": "head involution", "id": "GO:0008258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008258", "evidence": [ { "database": "UniProtKB", "id": "Q9VFU8", "url": "https://www.uniprot.org/uniprotkb/Q9VFU8" } ], "pmid": "" }, { "name": "amnioserosa maintenance", "id": "GO:0046665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046665", "evidence": [ { "database": "UniProtKB", "id": "Q9VFU8", "url": "https://www.uniprot.org/uniprotkb/Q9VFU8" } ], "pmid": "" }, { "name": "actomyosin structure organization", "id": "GO:0031032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031032", "evidence": [ { "database": "UniProtKB", "id": "Q9VFU8", "url": "https://www.uniprot.org/uniprotkb/Q9VFU8" } ], "pmid": "" } ], "molecular_function": [ { "name": "cytoskeletal protein binding", "id": "GO:0008092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008092", "evidence": [ { "database": "UniProtKB", "id": "Q9VFU8", "url": "https://www.uniprot.org/uniprotkb/Q9VFU8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VFU8-1", "start_pos": "471", "end_pos": "471", "site_lbl": "Thr471", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 471, "start_aa": "Thr", "end_pos": 471, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr471", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VFU8-1", "start_pos": "872", "end_pos": "872", "site_lbl": "Thr872", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 872, "start_aa": "Thr", "end_pos": 872, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr872", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VFU8-1" }, { "uniprot_canonical_ac": "B7Z0J4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7Z0J4", "url": "https://www.uniprot.org/uniprotkb/B7Z0J4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 80, "chemical_mass": 9036.0, "gene_names": "CG9288;CG42375;CG9288;Dmel\\CG42375;Dmel_CG42375;Dromel_CG9288_FBtr0082829_pyruvatekinasedomain_uORF", "protein_name": "COX assembly mitochondrial protein", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "B7Z0J4", "url": "https://www.uniprot.org/uniprotkb/B7Z0J4" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "B7Z0J4", "url": "https://www.uniprot.org/uniprotkb/B7Z0J4" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial respiratory chain complex IV assembly", "id": "GO:0033617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033617", "evidence": [ { "database": "UniProtKB", "id": "B7Z0J4", "url": "https://www.uniprot.org/uniprotkb/B7Z0J4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "B7Z0J4-1" }, { "uniprot_canonical_ac": "B7Z0N0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7Z0N0", "url": "https://www.uniprot.org/uniprotkb/B7Z0N0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 355, "chemical_mass": 39790.0, "gene_names": "LD05530;BEST:LD05530;CG5180;Dmel\\CG5180;Dmel_CG5180;LD05530", "protein_name": "MADF domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "B7Z0N0-1", "start_pos": "180", "end_pos": "180", "site_lbl": "Thr180", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 180, "start_aa": "Thr", "end_pos": 180, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr180", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "B7Z0N0-1" }, { "uniprot_canonical_ac": "B7Z0Q2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7Z0Q2", "url": "https://www.uniprot.org/uniprotkb/B7Z0Q2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 699, "chemical_mass": 79468.0, "gene_names": "5PtaseI;5PtaseI;5Ptasel;BcDNA:RE64196;CG31107;CG31110;CG42283;CG7613;Dmel\\CG42283;Dmel_CG42283;IPP;Inpp5a;dm5PtaseI", "protein_name": "inositol-polyphosphate 5-phosphatase", "disease": [], "biological_process": [ { "name": "phosphatidylinositol dephosphorylation", "id": "GO:0046856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046856", "evidence": [ { "database": "UniProtKB", "id": "B7Z0Q2", "url": "https://www.uniprot.org/uniprotkb/B7Z0Q2" } ], "pmid": "" }, { "name": "phosphatidylinositol metabolic process", "id": "GO:0046488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046488", "evidence": [ { "database": "UniProtKB", "id": "B7Z0Q2", "url": "https://www.uniprot.org/uniprotkb/B7Z0Q2" } ], "pmid": "" } ], "molecular_function": [ { "name": "inositol-polyphosphate 5-phosphatase activity", "id": "GO:0004445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004445", "evidence": [ { "database": "UniProtKB", "id": "B7Z0Q2", "url": "https://www.uniprot.org/uniprotkb/B7Z0Q2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "B7Z0Q2-1", "start_pos": "632", "end_pos": "632", "site_lbl": "Thr632", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 632, "start_aa": "Thr", "end_pos": 632, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr632", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "B7Z0Q2-1" }, { "uniprot_canonical_ac": "B7Z101-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7Z101", "url": "https://www.uniprot.org/uniprotkb/B7Z101" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 200, "chemical_mass": 17248.0, "gene_names": "Dmel\\CG10597;CG10597;Dmel\\CG10597;Dmel_CG10597", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "B7Z101-1" }, { "uniprot_canonical_ac": "B9ZW35-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B9ZW35", "url": "https://www.uniprot.org/uniprotkb/B9ZW35" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 766, "chemical_mass": 86840.0, "gene_names": "pyr;CG13194;DFGF8-2;DmPyr;Dmel\\CG13194;Dmel_CG13194;FGF8-like2;Pyr;fgf8-like;pyr", "protein_name": "", "disease": [], "biological_process": [ { "name": "mesodermal cell fate specification", "id": "GO:0007501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007501", "evidence": [ { "database": "UniProtKB", "id": "B9ZW35", "url": "https://www.uniprot.org/uniprotkb/B9ZW35" } ], "pmid": "" }, { "name": "glial cell development", "id": "GO:0021782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021782", "evidence": [ { "database": "UniProtKB", "id": "B9ZW35", "url": "https://www.uniprot.org/uniprotkb/B9ZW35" } ], "pmid": "" }, { "name": "mesodermal cell fate commitment", "id": "GO:0001710", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001710", "evidence": [ { "database": "UniProtKB", "id": "B9ZW35", "url": "https://www.uniprot.org/uniprotkb/B9ZW35" } ], "pmid": "" }, { "name": "positive regulation of glial cell proliferation", "id": "GO:0060252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060252", "evidence": [ { "database": "UniProtKB", "id": "B9ZW35", "url": "https://www.uniprot.org/uniprotkb/B9ZW35" } ], "pmid": "" }, { "name": "myoblast migration", "id": "GO:0051451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051451", "evidence": [ { "database": "UniProtKB", "id": "B9ZW35", "url": "https://www.uniprot.org/uniprotkb/B9ZW35" } ], "pmid": "" }, { "name": "mesodermal cell migration", "id": "GO:0008078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008078", "evidence": [ { "database": "UniProtKB", "id": "B9ZW35", "url": "https://www.uniprot.org/uniprotkb/B9ZW35" } ], "pmid": "" }, { "name": "cardioblast differentiation", "id": "GO:0010002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010002", "evidence": [ { "database": "UniProtKB", "id": "B9ZW35", "url": "https://www.uniprot.org/uniprotkb/B9ZW35" } ], "pmid": "" }, { "name": "mesoderm development", "id": "GO:0007498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007498", "evidence": [ { "database": "UniProtKB", "id": "B9ZW35", "url": "https://www.uniprot.org/uniprotkb/B9ZW35" } ], "pmid": "" }, { "name": "glial cell migration", "id": "GO:0008347", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008347", "evidence": [ { "database": "UniProtKB", "id": "B9ZW35", "url": "https://www.uniprot.org/uniprotkb/B9ZW35" } ], "pmid": "" }, { "name": "mesoderm migration involved in gastrulation", "id": "GO:0007509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007509", "evidence": [ { "database": "UniProtKB", "id": "B9ZW35", "url": "https://www.uniprot.org/uniprotkb/B9ZW35" } ], "pmid": "" }, { "name": "fibroblast growth factor receptor signaling pathway", "id": "GO:0008543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008543", "evidence": [ { "database": "UniProtKB", "id": "B9ZW35", "url": "https://www.uniprot.org/uniprotkb/B9ZW35" } ], "pmid": "" }, { "name": "glial cell projection elongation", "id": "GO:0106091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106091", "evidence": [ { "database": "UniProtKB", "id": "B9ZW35", "url": "https://www.uniprot.org/uniprotkb/B9ZW35" } ], "pmid": "" }, { "name": "lymph gland plasmatocyte differentiation", "id": "GO:0035169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035169", "evidence": [ { "database": "UniProtKB", "id": "B9ZW35", "url": "https://www.uniprot.org/uniprotkb/B9ZW35" } ], "pmid": "" }, { "name": "lymph gland crystal cell differentiation", "id": "GO:0035170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035170", "evidence": [ { "database": "UniProtKB", "id": "B9ZW35", "url": "https://www.uniprot.org/uniprotkb/B9ZW35" } ], "pmid": "" }, { "name": "myotube cell migration", "id": "GO:0110122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110122", "evidence": [ { "database": "UniProtKB", "id": "B9ZW35", "url": "https://www.uniprot.org/uniprotkb/B9ZW35" } ], "pmid": "" }, { "name": "larval visceral muscle development", "id": "GO:0007523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007523", "evidence": [ { "database": "UniProtKB", "id": "B9ZW35", "url": "https://www.uniprot.org/uniprotkb/B9ZW35" } ], "pmid": "" }, { "name": "larval somatic muscle development", "id": "GO:0007526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007526", "evidence": [ { "database": "UniProtKB", "id": "B9ZW35", "url": "https://www.uniprot.org/uniprotkb/B9ZW35" } ], "pmid": "" }, { "name": "pericardial nephrocyte differentiation", "id": "GO:0061320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061320", "evidence": [ { "database": "UniProtKB", "id": "B9ZW35", "url": "https://www.uniprot.org/uniprotkb/B9ZW35" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "B9ZW35", "url": "https://www.uniprot.org/uniprotkb/B9ZW35" } ], "pmid": "" } ], "molecular_function": [ { "name": "growth factor activity", "id": "GO:0008083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008083", "evidence": [ { "database": "UniProtKB", "id": "B9ZW35", "url": "https://www.uniprot.org/uniprotkb/B9ZW35" } ], "pmid": "" }, { "name": "receptor ligand activity", "id": "GO:0048018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048018", "evidence": [ { "database": "UniProtKB", "id": "B9ZW35", "url": "https://www.uniprot.org/uniprotkb/B9ZW35" } ], "pmid": "" }, { "name": "fibroblast growth factor receptor binding", "id": "GO:0005104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005104", "evidence": [ { "database": "UniProtKB", "id": "B9ZW35", "url": "https://www.uniprot.org/uniprotkb/B9ZW35" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "B9ZW35-1" }, { "uniprot_canonical_ac": "Q0E910-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0E910", "url": "https://www.uniprot.org/uniprotkb/Q0E910" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1222, "chemical_mass": 138108.0, "gene_names": "tapas;BcDNA:LD21403;CG8920;Dmel\\CG8920;Dmel_CG8920;TDRD7;Tapas;tapas;tap", "protein_name": "", "disease": [ { "disease_id": "DOID:0110247", "name": "cataract 36", "description": "A cataract that has_material_basis_in homozygous mutation in the TDRD7 gene on chromosome 9q22.33.", "url": "https://disease-ontology.org/term/DOID:0110247", "evidence": [ { "id": "0110247", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110247" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q0E910", "url": "https://www.uniprot.org/uniprotkb/Q0E910" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "Q0E910", "url": "https://www.uniprot.org/uniprotkb/Q0E910" } ], "pmid": "" }, { "name": "P granule", "id": "GO:0043186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043186", "evidence": [ { "database": "UniProtKB", "id": "Q0E910", "url": "https://www.uniprot.org/uniprotkb/Q0E910" } ], "pmid": "" } ], "biological_process": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "Q0E910", "url": "https://www.uniprot.org/uniprotkb/Q0E910" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "Q0E910", "url": "https://www.uniprot.org/uniprotkb/Q0E910" } ], "pmid": "" }, { "name": "secondary piRNA processing", "id": "GO:0140965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140965", "evidence": [ { "database": "UniProtKB", "id": "Q0E910", "url": "https://www.uniprot.org/uniprotkb/Q0E910" } ], "pmid": "" }, { "name": "transposable element silencing by piRNA-mediated mRNA destabilization", "id": "GO:0141009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141009", "evidence": [ { "database": "UniProtKB", "id": "Q0E910", "url": "https://www.uniprot.org/uniprotkb/Q0E910" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q0E910-1", "start_pos": "328", "end_pos": "328", "site_lbl": "Thr328", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 328, "start_aa": "Thr", "end_pos": 328, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr328", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q0E910-1", "start_pos": "335", "end_pos": "335", "site_lbl": "Thr335", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 335, "start_aa": "Thr", "end_pos": 335, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr335", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q0E910-1" }, { "uniprot_canonical_ac": "E1JGT2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JGT2", "url": "https://www.uniprot.org/uniprotkb/E1JGT2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 78, "chemical_mass": 8757.0, "gene_names": "Dmel\\CG44253;CG30194;CG44253;Dmel\\CG44253;Dmel_CG44253", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "E1JGT2-1" }, { "uniprot_canonical_ac": "Q59DZ7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q59DZ7", "url": "https://www.uniprot.org/uniprotkb/Q59DZ7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1054, "chemical_mass": 116547.0, "gene_names": "Ddr;CG11573;CG13985;CG33531;CG9488;CG9490;CT33540;DDR;Ddr;Dmel\\CG33531;Dmel_CG33531;ddr", "protein_name": "", "disease": [ { "disease_id": "DOID:0050156", "name": "idiopathic pulmonary fibrosis", "description": "A pulmonary fibrosis that is characterized by scarring of the lung characterized by stiffness in the lungs and makes it difficult to breathe.", "url": "https://disease-ontology.org/term/DOID:0050156", "evidence": [ { "id": "0050156", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050156" } ], "weight": 0.0 }, { "disease_id": "DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050866", "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ], "weight": 0.0 }, { "disease_id": "DOID:0112196", "name": "spondylometaepiphyseal dysplasia, short limb-hand type", "description": "A spondyloepimetaphyseal dysplasia characterized by short stature, short limbs and hands, and typical radiological features which include platyspondyly, metaphyseal, and epiphyseal involvement, short tubular bones of the limbs, and abnormal calcification of cartilage that has_material_basis_in homozygous or compound heterozygous mutation in the DDR2 gene on chromosome 1q23.3.", "url": "https://disease-ontology.org/term/DOID:0112196", "evidence": [ { "id": "0112196", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112196" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:12351", "name": "alcoholic hepatitis", "description": "", "url": "https://disease-ontology.org/term/DOID:12351", "evidence": [ { "id": "12351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12351" } ], "weight": 0.0 }, { "disease_id": "DOID:14018", "name": "alcoholic liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:14018", "evidence": [ { "id": "14018", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14018" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:2394", "name": "ovarian cancer", "description": "A female reproductive organ cancer that is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:2394", "evidence": [ { "id": "2394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2394" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 }, { "disease_id": "DOID:3347", "name": "osteosarcoma", "description": "A bone sarcoma that is located_in bone that has_material_basis_in cells of mesenchymal origin. It usually involves bones and less frequently extraosseous sites. It often involves the long bones (particularly distal femur, proximal tibia, and proximal humerus).", "url": "https://disease-ontology.org/term/DOID:3347", "evidence": [ { "id": "3347", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3347" } ], "weight": 0.0 }, { "disease_id": "DOID:3459", "name": "breast carcinoma", "description": "A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:3459", "evidence": [ { "id": "3459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3459" } ], "weight": 0.0 }, { "disease_id": "DOID:3500", "name": "gallbladder adenocarcinoma", "description": "A gallbladder carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3500", "evidence": [ { "id": "3500", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3500" } ], "weight": 0.0 }, { "disease_id": "DOID:3907", "name": "lung squamous cell carcinoma", "description": "A non-small cell lung carcinoma that has_material_basis_in the squamous cell.", "url": "https://disease-ontology.org/term/DOID:3907", "evidence": [ { "id": "3907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3907" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:4467", "name": "clear cell renal cell carcinoma", "description": "A renal cell carcinoma that has_material_basis_in cells that appear very pale or clear when examined under microscope.", "url": "https://disease-ontology.org/term/DOID:4467", "evidence": [ { "id": "4467", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4467" } ], "weight": 0.0 }, { "disease_id": "DOID:5520", "name": "head and neck squamous cell carcinoma", "description": "A head and neck carcinoma that has_material_basis_in squamous cells that line the moist, mucosal surfaces inside the head and neck.", "url": "https://disease-ontology.org/term/DOID:5520", "evidence": [ { "id": "5520", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5520" } ], "weight": 0.0 }, { "disease_id": "DOID:5627", "name": "adenosquamous gallbladder carcinoma", "description": "A gallbladder carcinoma that derives_from squamous cells and gland-like cells.", "url": "https://disease-ontology.org/term/DOID:5627", "evidence": [ { "id": "5627", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5627" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:8398", "name": "osteoarthritis", "description": "An arthritis that has_material_basis_in worn out cartilage located_in joint.", "url": "https://disease-ontology.org/term/DOID:8398", "evidence": [ { "id": "8398", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8398" } ], "weight": 0.0 }, { "disease_id": "DOID:8923", "name": "skin melanoma", "description": "A skin cancer that has_material_basis_in melanocytes.", "url": "https://disease-ontology.org/term/DOID:8923", "evidence": [ { "id": "8923", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8923" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9261", "name": "nasopharynx carcinoma", "description": "A pharynx cancer that is located in the nasopharynx, the uppermost region of the pharynx or throat, where the nasal passages and auditory tubes join the remainder of the upper respiratory tract.", "url": "https://disease-ontology.org/term/DOID:9261", "evidence": [ { "id": "9261", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9261" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q59DZ7", "url": "https://www.uniprot.org/uniprotkb/Q59DZ7" } ], "pmid": "" }, { "name": "transmembrane receptor protein tyrosine kinase activity", "id": "GO:0004714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004714", "evidence": [ { "database": "UniProtKB", "id": "Q59DZ7", "url": "https://www.uniprot.org/uniprotkb/Q59DZ7" } ], "pmid": "" }, { "name": "collagen binding", "id": "GO:0005518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005518", "evidence": [ { "database": "UniProtKB", "id": "Q59DZ7", "url": "https://www.uniprot.org/uniprotkb/Q59DZ7" } ], "pmid": "" }, { "name": "protein tyrosine kinase collagen receptor activity", "id": "GO:0038062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038062", "evidence": [ { "database": "UniProtKB", "id": "Q59DZ7", "url": "https://www.uniprot.org/uniprotkb/Q59DZ7" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q59DZ7", "url": "https://www.uniprot.org/uniprotkb/Q59DZ7" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "Q59DZ7", "url": "https://www.uniprot.org/uniprotkb/Q59DZ7" } ], "pmid": "" } ], "biological_process": [ { "name": "cell surface receptor protein tyrosine kinase signaling pathway", "id": "GO:0007169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007169", "evidence": [ { "database": "UniProtKB", "id": "Q59DZ7", "url": "https://www.uniprot.org/uniprotkb/Q59DZ7" } ], "pmid": "" }, { "name": "positive regulation of neuron projection development", "id": "GO:0010976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010976", "evidence": [ { "database": "UniProtKB", "id": "Q59DZ7", "url": "https://www.uniprot.org/uniprotkb/Q59DZ7" } ], "pmid": "" }, { "name": "positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051897", "evidence": [ { "database": "UniProtKB", "id": "Q59DZ7", "url": "https://www.uniprot.org/uniprotkb/Q59DZ7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q59DZ7-1" }, { "uniprot_canonical_ac": "E1JHL2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JHL2", "url": "https://www.uniprot.org/uniprotkb/E1JHL2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 406, "chemical_mass": 47780.0, "gene_names": "CG31791;CG31791;CG42627;CG43339;Dmel\\CG43339;Dmel_CG43339", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "E1JHL2-1" }, { "uniprot_canonical_ac": "E1JHS1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JHS1", "url": "https://www.uniprot.org/uniprotkb/E1JHS1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 111, "chemical_mass": 12348.0, "gene_names": "Sfp24Bd;CG42463;Dmel\\CG42463;Dmel_CG42463;Sfp24Bd", "protein_name": "", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "E1JHS1", "url": "https://www.uniprot.org/uniprotkb/E1JHS1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "E1JHS1-1" }, { "uniprot_canonical_ac": "E1JI53-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JI53", "url": "https://www.uniprot.org/uniprotkb/E1JI53" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 244, "chemical_mass": 28040.0, "gene_names": "Dmel\\CG32391;CG32391;Dmel\\CG32391;Dmel_CG32391", "protein_name": "Protein lifeguard 1", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "E1JI53-1" }, { "uniprot_canonical_ac": "E1JIB0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JIB0", "url": "https://www.uniprot.org/uniprotkb/E1JIB0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 184, "chemical_mass": 21261.0, "gene_names": "Dmel\\CG42536;CG42536;Dmel\\CG42536;Dmel_CG42536", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "E1JIB0-1" }, { "uniprot_canonical_ac": "E1JIL1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JIL1", "url": "https://www.uniprot.org/uniprotkb/E1JIL1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 503, "chemical_mass": 54561.0, "gene_names": "CG31303;CG4196;CG31303;CG4196;CG42542;Dmel\\CG42542;Dmel_CG42542", "protein_name": "GDT1 family protein", "disease": [ { "disease_id": "DOID:0050571", "name": "congenital disorder of glycosylation type II", "description": "A congenital disorder of glycosylation that involves malfunctioning trimming or processing of the protein-bound oligosaccharide chain.", "url": "https://disease-ontology.org/term/DOID:0050571", "evidence": [ { "id": "0050571", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050571" } ], "weight": 0.0 }, { "disease_id": "DOID:0070263", "name": "congenital disorder of glycosylation type IIk", "description": "A congenital disorder of glycosylation type II that has_material_basis_in an autosomal recessive mutation of the TMEM165 gene on chromosome 4q12.", "url": "https://disease-ontology.org/term/DOID:0070263", "evidence": [ { "id": "0070263", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070263" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "E1JIL1", "url": "https://www.uniprot.org/uniprotkb/E1JIL1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1JIL1", "url": "https://www.uniprot.org/uniprotkb/E1JIL1" } ], "pmid": "" } ], "biological_process": [ { "name": "calcium ion transmembrane transport", "id": "GO:0070588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070588", "evidence": [ { "database": "UniProtKB", "id": "E1JIL1", "url": "https://www.uniprot.org/uniprotkb/E1JIL1" } ], "pmid": "" }, { "name": "Golgi calcium ion homeostasis", "id": "GO:0032468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032468", "evidence": [ { "database": "UniProtKB", "id": "E1JIL1", "url": "https://www.uniprot.org/uniprotkb/E1JIL1" } ], "pmid": "" }, { "name": "Golgi calcium ion transport", "id": "GO:0032472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032472", "evidence": [ { "database": "UniProtKB", "id": "E1JIL1", "url": "https://www.uniprot.org/uniprotkb/E1JIL1" } ], "pmid": "" }, { "name": "manganese ion transmembrane transport", "id": "GO:0071421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071421", "evidence": [ { "database": "UniProtKB", "id": "E1JIL1", "url": "https://www.uniprot.org/uniprotkb/E1JIL1" } ], "pmid": "" }, { "name": "calcium ion transport", "id": "GO:0006816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006816", "evidence": [ { "database": "UniProtKB", "id": "E1JIL1", "url": "https://www.uniprot.org/uniprotkb/E1JIL1" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion transmembrane transporter activity", "id": "GO:0015085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015085", "evidence": [ { "database": "UniProtKB", "id": "E1JIL1", "url": "https://www.uniprot.org/uniprotkb/E1JIL1" } ], "pmid": "" }, { "name": "manganese ion transmembrane transporter activity", "id": "GO:0005384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005384", "evidence": [ { "database": "UniProtKB", "id": "E1JIL1", "url": "https://www.uniprot.org/uniprotkb/E1JIL1" } ], "pmid": "" }, { "name": "metal ion transmembrane transporter activity", "id": "GO:0046873", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046873", "evidence": [ { "database": "UniProtKB", "id": "E1JIL1", "url": "https://www.uniprot.org/uniprotkb/E1JIL1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "E1JIL1-1" }, { "uniprot_canonical_ac": "E1JIQ7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JIQ7", "url": "https://www.uniprot.org/uniprotkb/E1JIQ7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 556, "chemical_mass": 60893.0, "gene_names": "CG32921-ORFB;anon-WO0140519.217;CG32921-ORFB;CG32921;CG33934;CG4961;Dmel\\CG33934;Dmel_CG33934;anon-WO0140519.217", "protein_name": "Protein I'm not dead yet 2", "disease": [ { "disease_id": "DOID:0080453", "name": "developmental and epileptic encephalopathy 25", "description": "A developmental and epileptic encephalopathy characterized by onset in early infancy of refractory seizures, global developmental delay with intellectual disability, persistent neurologic symptoms, and dental anomalies that has_material_basis_in homozygous or compound heterozygous mutation in the SLC13A5 gene on chromosome 17p13.", "url": "https://disease-ontology.org/term/DOID:0080453", "evidence": [ { "id": "0080453", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080453" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1JIQ7", "url": "https://www.uniprot.org/uniprotkb/E1JIQ7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1JIQ7", "url": "https://www.uniprot.org/uniprotkb/E1JIQ7" } ], "pmid": "" } ], "biological_process": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "E1JIQ7", "url": "https://www.uniprot.org/uniprotkb/E1JIQ7" } ], "pmid": "" }, { "name": "citrate transport", "id": "GO:0015746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015746", "evidence": [ { "database": "UniProtKB", "id": "E1JIQ7", "url": "https://www.uniprot.org/uniprotkb/E1JIQ7" } ], "pmid": "" }, { "name": "succinate transport", "id": "GO:0015744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015744", "evidence": [ { "database": "UniProtKB", "id": "E1JIQ7", "url": "https://www.uniprot.org/uniprotkb/E1JIQ7" } ], "pmid": "" } ], "molecular_function": [ { "name": "citrate transmembrane transporter activity", "id": "GO:0015137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015137", "evidence": [ { "database": "UniProtKB", "id": "E1JIQ7", "url": "https://www.uniprot.org/uniprotkb/E1JIQ7" } ], "pmid": "" }, { "name": "succinate transmembrane transporter activity", "id": "GO:0015141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015141", "evidence": [ { "database": "UniProtKB", "id": "E1JIQ7", "url": "https://www.uniprot.org/uniprotkb/E1JIQ7" } ], "pmid": "" }, { "name": "dicarboxylic acid transmembrane transporter activity", "id": "GO:0005310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005310", "evidence": [ { "database": "UniProtKB", "id": "E1JIQ7", "url": "https://www.uniprot.org/uniprotkb/E1JIQ7" } ], "pmid": "" }, { "name": "C4-dicarboxylate transmembrane transporter activity", "id": "GO:0015556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015556", "evidence": [ { "database": "UniProtKB", "id": "E1JIQ7", "url": "https://www.uniprot.org/uniprotkb/E1JIQ7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "E1JIQ7-1" }, { "uniprot_canonical_ac": "E1JIS3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JIS3", "url": "https://www.uniprot.org/uniprotkb/E1JIS3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 53, "chemical_mass": 5661.0, "gene_names": "Sfp93F;CG42608;Dmel\\CG42608;Dmel_CG42608;Sfp93F", "protein_name": "", "disease": [], "biological_process": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "E1JIS3", "url": "https://www.uniprot.org/uniprotkb/E1JIS3" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E1JIS3", "url": "https://www.uniprot.org/uniprotkb/E1JIS3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "E1JIS3-1" }, { "uniprot_canonical_ac": "Q9VHR7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VHR7", "url": "https://www.uniprot.org/uniprotkb/Q9VHR7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 466, "chemical_mass": 56065.0, "gene_names": "Dmel\\CG7352;CG7352;Dmel\\CG7352;Dmel_CG7352", "protein_name": "Meiosis-specific nuclear structural protein 1", "disease": [ { "disease_id": "DOID:0051023", "name": "visceral heterotaxy 9", "description": "A visceral heterotaxy that is characterized by randomization of organ laterality, resulting in defects such as situs inversus and dextrocardia and that has_material_basis_in homozygous mutation in the MNS1 gene on chromosome 15q21.", "url": "https://disease-ontology.org/term/DOID:0051023", "evidence": [ { "id": "0051023", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051023" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR7", "url": "https://www.uniprot.org/uniprotkb/Q9VHR7" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR7", "url": "https://www.uniprot.org/uniprotkb/Q9VHR7" } ], "pmid": "" } ], "biological_process": [ { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR7", "url": "https://www.uniprot.org/uniprotkb/Q9VHR7" } ], "pmid": "" }, { "name": "cilium organization", "id": "GO:0044782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044782", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR7", "url": "https://www.uniprot.org/uniprotkb/Q9VHR7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VHR7-1" }, { "uniprot_canonical_ac": "E1JJ97-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JJ97", "url": "https://www.uniprot.org/uniprotkb/E1JJ97" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 92, "chemical_mass": 10575.0, "gene_names": "Dmel\\CG42577;CG42577;Dmel\\CG42577;Dmel_CG42577", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "E1JJ97-1" }, { "uniprot_canonical_ac": "E1JJF2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JJF2", "url": "https://www.uniprot.org/uniprotkb/E1JJF2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 385, "chemical_mass": 44985.0, "gene_names": "Dmel\\CG4558;CG4558;Dmel\\CG4558;Dmel_CG4558", "protein_name": "", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "E1JJF2", "url": "https://www.uniprot.org/uniprotkb/E1JJF2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "E1JJF2-1" }, { "uniprot_canonical_ac": "E2QCM9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E2QCM9", "url": "https://www.uniprot.org/uniprotkb/E2QCM9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 476, "chemical_mass": 54061.0, "gene_names": "Dh44-R2;CG12370;CG13156;DH-R;DH44-R2;DH44R2;DH[[44]]-R2;Dh44-R2;Dh442;Dh44R2;Dmel\\CG12370;Dmel_CG12370;anon-WO0170980.103;anon-WO0170980.104", "protein_name": "Diuretic hormone receptor", "disease": [ { "disease_id": "DOID:0050696", "name": "fetal alcohol spectrum disorder", "description": "A specific developmental disorder and physical disorder that is characterized by physical, behavioral and learning birth defects resulting from maternal ingestion of alcohol during pregnancy.", "url": "https://disease-ontology.org/term/DOID:0050696", "evidence": [ { "id": "0050696", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050696" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:12918", "name": "thromboangiitis obliterans", "description": "", "url": "https://disease-ontology.org/term/DOID:12918", "evidence": [ { "id": "12918", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12918" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:3877", "name": "functional colonic disease", "description": "", "url": "https://disease-ontology.org/term/DOID:3877", "evidence": [ { "id": "3877", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3877" } ], "weight": 0.0 }, { "disease_id": "DOID:4483", "name": "rhinitis", "description": "A upper respiratory infectious disease which involves irritation and inflammation of the mucous membrane of the nose due to viruses, bacteria or irritants. The inflammation results in generation of excessive amounts of mucus leading to runny nose, as well as nasal congestion and post-nasal drip.", "url": "https://disease-ontology.org/term/DOID:4483", "evidence": [ { "id": "4483", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4483" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9778", "name": "irritable bowel syndrome", "description": "An intestinal disease that is characterized by chronic abdominal pain, discomfort, bloating, and alteration of bowel habits in the absence of any detectable organic cause.", "url": "https://disease-ontology.org/term/DOID:9778", "evidence": [ { "id": "9778", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9778" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 }, { "disease_id": "DOID:9976", "name": "heroin dependence", "description": "An opiate dependence that involves the continued use of heroin despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:9976", "evidence": [ { "id": "9976", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9976" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E2QCM9", "url": "https://www.uniprot.org/uniprotkb/E2QCM9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E2QCM9", "url": "https://www.uniprot.org/uniprotkb/E2QCM9" } ], "pmid": "" } ], "biological_process": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "E2QCM9", "url": "https://www.uniprot.org/uniprotkb/E2QCM9" } ], "pmid": "" }, { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "E2QCM9", "url": "https://www.uniprot.org/uniprotkb/E2QCM9" } ], "pmid": "" }, { "name": "adenylate cyclase-modulating G protein-coupled receptor signaling pathway", "id": "GO:0007188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007188", "evidence": [ { "database": "UniProtKB", "id": "E2QCM9", "url": "https://www.uniprot.org/uniprotkb/E2QCM9" } ], "pmid": "" }, { "name": "hormone-mediated signaling pathway", "id": "GO:0009755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009755", "evidence": [ { "database": "UniProtKB", "id": "E2QCM9", "url": "https://www.uniprot.org/uniprotkb/E2QCM9" } ], "pmid": "" }, { "name": "response to salt stress", "id": "GO:0009651", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009651", "evidence": [ { "database": "UniProtKB", "id": "E2QCM9", "url": "https://www.uniprot.org/uniprotkb/E2QCM9" } ], "pmid": "" } ], "molecular_function": [ { "name": "peptide hormone binding", "id": "GO:0017046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017046", "evidence": [ { "database": "UniProtKB", "id": "E2QCM9", "url": "https://www.uniprot.org/uniprotkb/E2QCM9" } ], "pmid": "" }, { "name": "G protein-coupled peptide receptor activity", "id": "GO:0008528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008528", "evidence": [ { "database": "UniProtKB", "id": "E2QCM9", "url": "https://www.uniprot.org/uniprotkb/E2QCM9" } ], "pmid": "" }, { "name": "calcitonin receptor activity", "id": "GO:0004948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004948", "evidence": [ { "database": "UniProtKB", "id": "E2QCM9", "url": "https://www.uniprot.org/uniprotkb/E2QCM9" } ], "pmid": "" }, { "name": "neuropeptide receptor activity", "id": "GO:0008188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008188", "evidence": [ { "database": "UniProtKB", "id": "E2QCM9", "url": "https://www.uniprot.org/uniprotkb/E2QCM9" } ], "pmid": "" }, { "name": "diuretic hormone receptor activity", "id": "GO:0008036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008036", "evidence": [ { "database": "UniProtKB", "id": "E2QCM9", "url": "https://www.uniprot.org/uniprotkb/E2QCM9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "E2QCM9-1" }, { "uniprot_canonical_ac": "Q9V491-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V491", "url": "https://www.uniprot.org/uniprotkb/Q9V491" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1945, "chemical_mass": 218358.0, "gene_names": "PlexA;BcDNA:GM05237;CG11081;D-Plex A;DPlexA;Dmel\\CG11081;Dmel_CG11081;Plex1;PlexA1;PlexA;Plexa;PlexinA;lincRNA.927;plex A;plexA;plex", "protein_name": "", "disease": [], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "Q9V491", "url": "https://www.uniprot.org/uniprotkb/Q9V491" } ], "pmid": "" }, { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "Q9V491", "url": "https://www.uniprot.org/uniprotkb/Q9V491" } ], "pmid": "" }, { "name": "14-3-3 protein binding", "id": "GO:0071889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071889", "evidence": [ { "database": "UniProtKB", "id": "Q9V491", "url": "https://www.uniprot.org/uniprotkb/Q9V491" } ], "pmid": "" }, { "name": "semaphorin receptor activity", "id": "GO:0017154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017154", "evidence": [ { "database": "UniProtKB", "id": "Q9V491", "url": "https://www.uniprot.org/uniprotkb/Q9V491" } ], "pmid": "" }, { "name": "guanylate cyclase activator activity", "id": "GO:0030250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030250", "evidence": [ { "database": "UniProtKB", "id": "Q9V491", "url": "https://www.uniprot.org/uniprotkb/Q9V491" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9V491", "url": "https://www.uniprot.org/uniprotkb/Q9V491" } ], "pmid": "" }, { "name": "semaphorin receptor complex", "id": "GO:0002116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002116", "evidence": [ { "database": "UniProtKB", "id": "Q9V491", "url": "https://www.uniprot.org/uniprotkb/Q9V491" } ], "pmid": "" } ], "biological_process": [ { "name": "axon midline choice point recognition", "id": "GO:0016199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016199", "evidence": [ { "database": "UniProtKB", "id": "Q9V491", "url": "https://www.uniprot.org/uniprotkb/Q9V491" } ], "pmid": "" }, { "name": "Ras protein signal transduction", "id": "GO:0007265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007265", "evidence": [ { "database": "UniProtKB", "id": "Q9V491", "url": "https://www.uniprot.org/uniprotkb/Q9V491" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "Q9V491", "url": "https://www.uniprot.org/uniprotkb/Q9V491" } ], "pmid": "" }, { "name": "sensory neuron axon guidance", "id": "GO:0097374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097374", "evidence": [ { "database": "UniProtKB", "id": "Q9V491", "url": "https://www.uniprot.org/uniprotkb/Q9V491" } ], "pmid": "" }, { "name": "semaphorin-plexin signaling pathway", "id": "GO:0071526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071526", "evidence": [ { "database": "UniProtKB", "id": "Q9V491", "url": "https://www.uniprot.org/uniprotkb/Q9V491" } ], "pmid": "" }, { "name": "synapse assembly", "id": "GO:0007416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007416", "evidence": [ { "database": "UniProtKB", "id": "Q9V491", "url": "https://www.uniprot.org/uniprotkb/Q9V491" } ], "pmid": "" }, { "name": "regulation of cell migration", "id": "GO:0030334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334", "evidence": [ { "database": "UniProtKB", "id": "Q9V491", "url": "https://www.uniprot.org/uniprotkb/Q9V491" } ], "pmid": "" }, { "name": "photoreceptor cell axon guidance", "id": "GO:0072499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072499", "evidence": [ { "database": "UniProtKB", "id": "Q9V491", "url": "https://www.uniprot.org/uniprotkb/Q9V491" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9V491-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Asn114", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": { "label": "iCn3D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?bcifid=6FKM&bu=0&command=select+.A:114;+center+selection;+zoom+selection" }, "start_pos": 114, "start_aa": "Asn", "end_pos": 114, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn114", "evidence": [ { "id": "Q9V491", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V491#ptm_processing" }, { "id": "6FKM", "database": "PDB", "url": "https://www.rcsb.org/sequence/6FKM" }, { "id": "6FKN", "database": "PDB", "url": "https://www.rcsb.org/sequence/6FKN" }, { "id": "6FKM", "database": "PDB", "url": "https://www.rcsb.org/structure/6FKM" }, { "id": "6FKM", "database": "PDB", "url": "https://www.rcsb.org/structure/6FKM" }, { "id": "6FKN", "database": "PDB", "url": "https://www.rcsb.org/structure/6FKN" }, { "id": "6FKN", "database": "PDB", "url": "https://www.rcsb.org/structure/6FKN" }, { "id": "6FKM|A|114", "database": "", "url": "" }, { "id": "6FKN|C|114", "database": "", "url": "" }, { "id": "6FKN|A|114", "database": "", "url": "" } ] } ] }, { "uniprot_canonical_ac": "Q9V491-1", "start_pos": "167", "end_pos": "167", "site_lbl": "Asn167", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": { "label": "iCn3D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?bcifid=6FKM&bu=0&command=select+.A:167;+center+selection;+zoom+selection" }, "start_pos": 167, "start_aa": "Asn", "end_pos": 167, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn167", "evidence": [ { "id": "Q9V491", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V491#ptm_processing" }, { "id": "6FKM", "database": "PDB", "url": "https://www.rcsb.org/sequence/6FKM" }, { "id": "6FKN", "database": "PDB", "url": "https://www.rcsb.org/sequence/6FKN" }, { "id": "6FKM", "database": "PDB", "url": "https://www.rcsb.org/structure/6FKM" }, { "id": "6FKM", "database": "PDB", "url": "https://www.rcsb.org/structure/6FKM" }, { "id": "6FKN", "database": "PDB", "url": "https://www.rcsb.org/structure/6FKN" }, { "id": "6FKN", "database": "PDB", "url": "https://www.rcsb.org/structure/6FKN" }, { "id": "6FKM|A|167", "database": "", "url": "" }, { "id": "6FKN|C|167", "database": "", "url": "" }, { "id": "6FKN|A|167", "database": "", "url": "" } ] } ] }, { "uniprot_canonical_ac": "Q9V491-1", "start_pos": "185", "end_pos": "185", "site_lbl": "Asn185", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": { "label": "iCn3D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?bcifid=6FKM&bu=0&command=select+.A:185;+center+selection;+zoom+selection" }, "start_pos": 185, "start_aa": "Asn", "end_pos": 185, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn185", "evidence": [ { "id": "Q9V491", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V491#ptm_processing" }, { "id": "6FKM", "database": "PDB", "url": "https://www.rcsb.org/sequence/6FKM" }, { "id": "6FKN", "database": "PDB", "url": "https://www.rcsb.org/sequence/6FKN" }, { "id": "6FKM", "database": "PDB", "url": "https://www.rcsb.org/structure/6FKM" }, { "id": "6FKM", "database": "PDB", "url": "https://www.rcsb.org/structure/6FKM" }, { "id": "6FKN", "database": "PDB", "url": "https://www.rcsb.org/structure/6FKN" }, { "id": "6FKN", "database": "PDB", "url": "https://www.rcsb.org/structure/6FKN" }, { "id": "6FKM|A|185", "database": "", "url": "" }, { "id": "6FKN|C|185", "database": "", "url": "" }, { "id": "6FKN|A|185", "database": "", "url": "" } ] } ] }, { "uniprot_canonical_ac": "Q9V491-1", "start_pos": "366", "end_pos": "366", "site_lbl": "Asn366", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": { "label": "iCn3D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?bcifid=6FKM&bu=0&command=select+.A:366;+center+selection;+zoom+selection" }, "start_pos": 366, "start_aa": "Asn", "end_pos": 366, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn366", "evidence": [ { "id": "Q9V491", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V491#ptm_processing" }, { "id": "6FKM", "database": "PDB", "url": "https://www.rcsb.org/sequence/6FKM" }, { "id": "6FKM", "database": "PDB", "url": "https://www.rcsb.org/structure/6FKM" }, { "id": "6FKM", "database": "PDB", "url": "https://www.rcsb.org/structure/6FKM" }, { "id": "6FKM|A|366", "database": "", "url": "" } ] } ] }, { "uniprot_canonical_ac": "Q9V491-1", "start_pos": "723", "end_pos": "723", "site_lbl": "Ser723", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 723, "start_aa": "Ser", "end_pos": 723, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser723", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9V491", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9V491" } ] } ] }, { "uniprot_canonical_ac": "Q9V491-1", "start_pos": "990", "end_pos": "990", "site_lbl": "Thr990", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 990, "start_aa": "Thr", "end_pos": 990, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr990", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9V491-1" }, { "uniprot_canonical_ac": "M9ND53-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9ND53", "url": "https://www.uniprot.org/uniprotkb/M9ND53" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2047, "chemical_mass": 215083.0, "gene_names": "tai;2;58/2;CG13109;CG18494;DAIB1;DmTaiman;DmTai;Dmel\\CG13109;Dmel_CG13109;EP(2)2630;NEST:bs13g05;TAI;Taiman;Tai;bs13g05.y1;l(2)01351;l(2)k05802;l(2)k05809;tai", "protein_name": "", "disease": [ { "disease_id": "DOID:0050861", "name": "colorectal adenocarcinoma", "description": "A colorectal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:0050861", "evidence": [ { "id": "0050861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050861" } ], "weight": 0.0 }, { "disease_id": "DOID:0080199", "name": "colorectal carcinoma", "description": "A colorectal cancer that arises from the colon or rectum and invades through the muscularis mucosa into the submucosa.", "url": "https://disease-ontology.org/term/DOID:0080199", "evidence": [ { "id": "0080199", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080199" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:11612", "name": "polycystic ovary syndrome", "description": "An ovarian dysfunction that is characterized by hyperandrogenism, polycystic ovaries, hirsutism, oligomenorrhea or amenorrhea, anovulation and excessive body weight.", "url": "https://disease-ontology.org/term/DOID:11612", "evidence": [ { "id": "11612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11612" } ], "weight": 0.0 }, { "disease_id": "DOID:11633", "name": "thyroid hormone resistance syndrome", "description": "", "url": "https://disease-ontology.org/term/DOID:11633", "evidence": [ { "id": "11633", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11633" } ], "weight": 0.0 }, { "disease_id": "DOID:1459", "name": "hypothyroidism", "description": "A thyroid gland disease which involves an underproduction of thyroid hormone.", "url": "https://disease-ontology.org/term/DOID:1459", "evidence": [ { "id": "1459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1459" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:2526", "name": "prostate adenocarcinoma", "description": "A prostate carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:2526", "evidence": [ { "id": "2526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2526" } ], "weight": 0.0 }, { "disease_id": "DOID:2871", "name": "endometrial carcinoma", "description": "A endometrial cancer that is located_in the tissue lining the uterus.", "url": "https://disease-ontology.org/term/DOID:2871", "evidence": [ { "id": "2871", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2871" } ], "weight": 0.0 }, { "disease_id": "DOID:3459", "name": "breast carcinoma", "description": "A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:3459", "evidence": [ { "id": "3459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3459" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:7474", "name": "malignant pleural mesothelioma", "description": "A pleural cancer that has_material_basis_in mesothelium cells.", "url": "https://disease-ontology.org/term/DOID:7474", "evidence": [ { "id": "7474", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7474" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "M9ND53", "url": "https://www.uniprot.org/uniprotkb/M9ND53" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "M9ND53", "url": "https://www.uniprot.org/uniprotkb/M9ND53" } ], "pmid": "" }, { "name": "nuclear receptor binding", "id": "GO:0016922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016922", "evidence": [ { "database": "UniProtKB", "id": "M9ND53", "url": "https://www.uniprot.org/uniprotkb/M9ND53" } ], "pmid": "" }, { "name": "transcription coactivator binding", "id": "GO:0001223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001223", "evidence": [ { "database": "UniProtKB", "id": "M9ND53", "url": "https://www.uniprot.org/uniprotkb/M9ND53" } ], "pmid": "" }, { "name": "transcription regulator inhibitor activity", "id": "GO:0140416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140416", "evidence": [ { "database": "UniProtKB", "id": "M9ND53", "url": "https://www.uniprot.org/uniprotkb/M9ND53" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9ND53", "url": "https://www.uniprot.org/uniprotkb/M9ND53" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "M9ND53", "url": "https://www.uniprot.org/uniprotkb/M9ND53" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "M9ND53", "url": "https://www.uniprot.org/uniprotkb/M9ND53" } ], "pmid": "" }, { "name": "positive regulation of growth", "id": "GO:0045927", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045927", "evidence": [ { "database": "UniProtKB", "id": "M9ND53", "url": "https://www.uniprot.org/uniprotkb/M9ND53" } ], "pmid": "" }, { "name": "border follicle cell migration", "id": "GO:0007298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007298", "evidence": [ { "database": "UniProtKB", "id": "M9ND53", "url": "https://www.uniprot.org/uniprotkb/M9ND53" } ], "pmid": "" }, { "name": "germ-line stem-cell niche homeostasis", "id": "GO:0060250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060250", "evidence": [ { "database": "UniProtKB", "id": "M9ND53", "url": "https://www.uniprot.org/uniprotkb/M9ND53" } ], "pmid": "" }, { "name": "positive regulation of border follicle cell migration", "id": "GO:1903688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903688", "evidence": [ { "database": "UniProtKB", "id": "M9ND53", "url": "https://www.uniprot.org/uniprotkb/M9ND53" } ], "pmid": "" }, { "name": "cellular response to hormone stimulus", "id": "GO:0032870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032870", "evidence": [ { "database": "UniProtKB", "id": "M9ND53", "url": "https://www.uniprot.org/uniprotkb/M9ND53" } ], "pmid": "" }, { "name": "negative regulation of smoothened signaling pathway", "id": "GO:0045879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045879", "evidence": [ { "database": "UniProtKB", "id": "M9ND53", "url": "https://www.uniprot.org/uniprotkb/M9ND53" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9ND53-1", "start_pos": "1492", "end_pos": "1492", "site_lbl": "Thr1492", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1492, "start_aa": "Thr", "end_pos": 1492, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1492", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9ND53-1" }, { "uniprot_canonical_ac": "M9MRI7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9MRI7", "url": "https://www.uniprot.org/uniprotkb/M9MRI7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 43, "chemical_mass": 5313.0, "gene_names": "Dmel\\CG42751;CG42751;Dmel\\CG42751;Dmel_CG42751", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9MRI7-1" }, { "uniprot_canonical_ac": "Q8IP51-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IP51", "url": "https://www.uniprot.org/uniprotkb/Q8IP51" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 3375, "chemical_mass": 374749.0, "gene_names": "wb;2Lan;2]];2;A1;BEST:CK02229;BG:DS03792.1;BG:DS03792.2;CG15288;CG32970;CG42677;CK02229;CT35236;DLAM;Dmel\\CG42677;Dmel_CG42677;LM-A/alpha2;LanA1;LanWb;Wb;alpha1;alpha2;alpha[[1;fus5;l(2)09437;l(2)34Fb;l(2)br1;l34Fb;wb", "protein_name": "", "disease": [ { "disease_id": "DOID:0061132", "name": "autosomal recessive limb-girdle muscular dystrophy type 23", "description": "An autosomal recessive limb-girdle muscular dystrophy characterized by slowly progressive proximal muscle weakness primarily affecting the lower limbs and resulting in gait difficulties that has_material_basis_in y homozygous or compound heterozygous mutation in the LAMA2 gene on chromosome 6q22.", "url": "https://disease-ontology.org/term/DOID:0061132", "evidence": [ { "id": "0061132", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061132" } ], "weight": 0.0 }, { "disease_id": "DOID:0110636", "name": "congenital merosin-deficient muscular dystrophy 1A", "description": "A congenital muscular dystrophy characterized by autosomal recessive inheritance of muscle weakness that is apparent at birth or in the first 6 months of life and frequent development of periventricular white matter abnormalities that has_material_basis_in homozygous or compound heterozygous mutation in the LAMA2 gene on chromosome 6q22.", "url": "https://disease-ontology.org/term/DOID:0110636", "evidence": [ { "id": "0110636", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110636" } ], "weight": 0.0 }, { "disease_id": "DOID:11830", "name": "myopia", "description": "A refractive error characterized by the inability to see farther objects clearly.", "url": "https://disease-ontology.org/term/DOID:11830", "evidence": [ { "id": "11830", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11830" } ], "weight": 0.0 }, { "disease_id": "DOID:1591", "name": "renovascular hypertension", "description": "", "url": "https://disease-ontology.org/term/DOID:1591", "evidence": [ { "id": "1591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1591" } ], "weight": 0.0 }, { "disease_id": "DOID:9884", "name": "muscular dystrophy", "description": "A myopathy is characterized by progressive skeletal muscle weakness degeneration.", "url": "https://disease-ontology.org/term/DOID:9884", "evidence": [ { "id": "9884", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9884" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "Q8IP51", "url": "https://www.uniprot.org/uniprotkb/Q8IP51" } ], "pmid": "" }, { "name": "gonad development", "id": "GO:0008406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008406", "evidence": [ { "database": "UniProtKB", "id": "Q8IP51", "url": "https://www.uniprot.org/uniprotkb/Q8IP51" } ], "pmid": "" }, { "name": "digestive tract mesoderm development", "id": "GO:0007502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007502", "evidence": [ { "database": "UniProtKB", "id": "Q8IP51", "url": "https://www.uniprot.org/uniprotkb/Q8IP51" } ], "pmid": "" }, { "name": "animal organ morphogenesis", "id": "GO:0009887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887", "evidence": [ { "database": "UniProtKB", "id": "Q8IP51", "url": "https://www.uniprot.org/uniprotkb/Q8IP51" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "Q8IP51", "url": "https://www.uniprot.org/uniprotkb/Q8IP51" } ], "pmid": "" }, { "name": "tissue development", "id": "GO:0009888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009888", "evidence": [ { "database": "UniProtKB", "id": "Q8IP51", "url": "https://www.uniprot.org/uniprotkb/Q8IP51" } ], "pmid": "" }, { "name": "epithelial structure maintenance", "id": "GO:0010669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010669", "evidence": [ { "database": "UniProtKB", "id": "Q8IP51", "url": "https://www.uniprot.org/uniprotkb/Q8IP51" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "Q8IP51", "url": "https://www.uniprot.org/uniprotkb/Q8IP51" } ], "pmid": "" } ], "cellular_component": [ { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "Q8IP51", "url": "https://www.uniprot.org/uniprotkb/Q8IP51" } ], "pmid": "" } ], "molecular_function": [ { "name": "extracellular matrix structural constituent", "id": "GO:0005201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005201", "evidence": [ { "database": "UniProtKB", "id": "Q8IP51", "url": "https://www.uniprot.org/uniprotkb/Q8IP51" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IP51-1" }, { "uniprot_canonical_ac": "M9MSI4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9MSI4", "url": "https://www.uniprot.org/uniprotkb/M9MSI4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 564, "chemical_mass": 64577.0, "gene_names": "DS05899.7;BG:DS05899.7;CG18095;DS05899.7;Dmel\\CG18095;Dmel_CG18095", "protein_name": "", "disease": [ { "disease_id": "DOID:0060870", "name": "isolated growth hormone deficiency", "description": "A hypopituitarism characterized by abnormally low levels, absence or impaired function of growth hormone in the absence of abnormalities in other pituitary hormones.", "url": "https://disease-ontology.org/term/DOID:0060870", "evidence": [ { "id": "0060870", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060870" } ], "weight": 0.0 }, { "disease_id": "DOID:0080552", "name": "congenital disorder of glycosylation Ia", "description": "A congenital disorder of glycosylation I that is characterized by a severe encephalopathy with axial hypotonia, abnormal eye movement, pronounced psychomotor retardation, peripheral neuropathy, cerebellar hypoplasia, and retinitis pigmentosa and has_material_basis_in homozygous or compound heterozygous mutation in the gene encoding phosphomannomutase-2 on chromosome 16p13.", "url": "https://disease-ontology.org/term/DOID:0080552", "evidence": [ { "id": "0080552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080552" } ], "weight": 0.0 }, { "disease_id": "DOID:1184", "name": "nephrotic syndrome", "description": "A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.", "url": "https://disease-ontology.org/term/DOID:1184", "evidence": [ { "id": "1184", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1184" } ], "weight": 0.0 }, { "disease_id": "DOID:3490", "name": "Noonan syndrome", "description": "A RASopathy that is characterized by mildly unusual facial features, short stature, heart defects, bleeding problems, skeletal malformations, and many other signs and symptoms.", "url": "https://disease-ontology.org/term/DOID:3490", "evidence": [ { "id": "3490", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3490" } ], "weight": 0.0 }, { "disease_id": "DOID:8689", "name": "anorexia nervosa", "description": "An eating disorder characterized by refusal to maintain a healthy body weight, and an obsessive fear of gaining weight due to a distorted self image.", "url": "https://disease-ontology.org/term/DOID:8689", "evidence": [ { "id": "8689", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8689" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "M9MSI4", "url": "https://www.uniprot.org/uniprotkb/M9MSI4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9MSI4-1" }, { "uniprot_canonical_ac": "M9MSI7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9MSI7", "url": "https://www.uniprot.org/uniprotkb/M9MSI7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1085, "chemical_mass": 121896.0, "gene_names": "Dmel\\CG42818;BG:DS07473.1;CG12455;CG42818;DS07473.1A;Dmel\\CG42818;Dmel_CG42818", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9MSI7-1" }, { "uniprot_canonical_ac": "M9NCU2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NCU2", "url": "https://www.uniprot.org/uniprotkb/M9NCU2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 73, "chemical_mass": 8691.0, "gene_names": "Dmel\\CG43376;CG43376;Dmel\\CG43376;Dmel_CG43376", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9NCU2-1" }, { "uniprot_canonical_ac": "M9NDD9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NDD9", "url": "https://www.uniprot.org/uniprotkb/M9NDD9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 95, "chemical_mass": 10712.0, "gene_names": "Dmel\\CG43165;CG43165;Dmel\\CG43165;Dmel_CG43165", "protein_name": "BPTI/Kunitz inhibitor domain-containing protein", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "M9NDD9", "url": "https://www.uniprot.org/uniprotkb/M9NDD9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9NDD9-1" }, { "uniprot_canonical_ac": "M9NDH2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NDH2", "url": "https://www.uniprot.org/uniprotkb/M9NDH2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 71, "chemical_mass": 8130.0, "gene_names": "Dmel\\CG43182;CG43182;Dmel\\CG43182;Dmel_CG43182;FBgn0262811", "protein_name": "Secreted protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9NDH2-1" }, { "uniprot_canonical_ac": "M9NDZ8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NDZ8", "url": "https://www.uniprot.org/uniprotkb/M9NDZ8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 182, "chemical_mass": 20946.0, "gene_names": "Dmel\\CG43074;CG43074;Dmel\\CG43074;Dmel_CG43074", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9NDZ8-1" }, { "uniprot_canonical_ac": "M9NDZ9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NDZ9", "url": "https://www.uniprot.org/uniprotkb/M9NDZ9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 253, "chemical_mass": 28780.0, "gene_names": "Dmel\\CG43331;CG12377;CG43331;Dmel\\CG43331;Dmel_CG43331", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9NDZ9-1" }, { "uniprot_canonical_ac": "M9PJN5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PJN5", "url": "https://www.uniprot.org/uniprotkb/M9PJN5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1179, "chemical_mass": 130897.0, "gene_names": "HDAC6;CG6170;DHDAC2;DmHDAC2;Dmel\\CG6170;Dmel_CG6170;HDAC2;HDAC6;HDAC;Hdac6;dHDAC2;dHDAC6;dmHDA404;hDAC6;hdac6", "protein_name": "Protein deacetylase HDAC6", "disease": [ { "disease_id": "DOID:0060980", "name": "polycystic liver disease 1", "description": "A polycystic disease characterized by the presence of multiple liver cysts of biliary epithelial origin that has_material_basis_in heterozygous mutation in the PRKCSH gene on chromosome 19p13.", "url": "https://disease-ontology.org/term/DOID:0060980", "evidence": [ { "id": "0060980", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060980" } ], "weight": 0.0 }, { "disease_id": "DOID:0080322", "name": "polycystic kidney disease", "description": "A cystic kidney disease that is characterized by the growth of fluid-filled cysts in the kidneys that reduces kidney function and may lead to kidney failure.", "url": "https://disease-ontology.org/term/DOID:0080322", "evidence": [ { "id": "0080322", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080322" } ], "weight": 0.0 }, { "disease_id": "DOID:0112106", "name": "chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia", "description": "A syndrome characterized by chondrodysplasia associated with other features including intrauterine growth retardation, hydrocephaly, macrocephaly, frontal bossing, microphthalmia, small low-set ears, and short flat nose that has_material_basis_in heterozygous mutation in the HDAC6 gene on chromosome Xp11.23.", "url": "https://disease-ontology.org/term/DOID:0112106", "evidence": [ { "id": "0112106", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112106" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:4947", "name": "cholangiocarcinoma", "description": "A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4947", "evidence": [ { "id": "4947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4947" } ], "weight": 0.0 }, { "disease_id": "DOID:8991", "name": "cervix uteri carcinoma in situ", "description": "An uterus carcinoma in situ that is located_in the uterine cervix.", "url": "https://disease-ontology.org/term/DOID:8991", "evidence": [ { "id": "8991", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8991" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PJN5", "url": "https://www.uniprot.org/uniprotkb/M9PJN5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9PJN5", "url": "https://www.uniprot.org/uniprotkb/M9PJN5" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "M9PJN5", "url": "https://www.uniprot.org/uniprotkb/M9PJN5" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "M9PJN5", "url": "https://www.uniprot.org/uniprotkb/M9PJN5" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "M9PJN5", "url": "https://www.uniprot.org/uniprotkb/M9PJN5" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "M9PJN5", "url": "https://www.uniprot.org/uniprotkb/M9PJN5" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "M9PJN5", "url": "https://www.uniprot.org/uniprotkb/M9PJN5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "M9PJN5", "url": "https://www.uniprot.org/uniprotkb/M9PJN5" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "M9PJN5", "url": "https://www.uniprot.org/uniprotkb/M9PJN5" } ], "pmid": "" }, { "name": "neurotransmitter secretion", "id": "GO:0007269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007269", "evidence": [ { "database": "UniProtKB", "id": "M9PJN5", "url": "https://www.uniprot.org/uniprotkb/M9PJN5" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "M9PJN5", "url": "https://www.uniprot.org/uniprotkb/M9PJN5" } ], "pmid": "" }, { "name": "response to stress", "id": "GO:0006950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006950", "evidence": [ { "database": "UniProtKB", "id": "M9PJN5", "url": "https://www.uniprot.org/uniprotkb/M9PJN5" } ], "pmid": "" }, { "name": "regulation of microtubule-based process", "id": "GO:0032886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032886", "evidence": [ { "database": "UniProtKB", "id": "M9PJN5", "url": "https://www.uniprot.org/uniprotkb/M9PJN5" } ], "pmid": "" }, { "name": "mitochondrion localization", "id": "GO:0051646", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051646", "evidence": [ { "database": "UniProtKB", "id": "M9PJN5", "url": "https://www.uniprot.org/uniprotkb/M9PJN5" } ], "pmid": "" }, { "name": "negative regulation of cellular component organization", "id": "GO:0051129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051129", "evidence": [ { "database": "UniProtKB", "id": "M9PJN5", "url": "https://www.uniprot.org/uniprotkb/M9PJN5" } ], "pmid": "" } ], "molecular_function": [ { "name": "deacetylase activity", "id": "GO:0019213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019213", "evidence": [ { "database": "UniProtKB", "id": "M9PJN5", "url": "https://www.uniprot.org/uniprotkb/M9PJN5" } ], "pmid": "" }, { "name": "histone deacetylase activity", "id": "GO:0004407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004407", "evidence": [ { "database": "UniProtKB", "id": "M9PJN5", "url": "https://www.uniprot.org/uniprotkb/M9PJN5" } ], "pmid": "" }, { "name": "histone deacetylase activity, hydrolytic mechanism", "id": "GO:0141221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141221", "evidence": [ { "database": "UniProtKB", "id": "M9PJN5", "url": "https://www.uniprot.org/uniprotkb/M9PJN5" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "M9PJN5", "url": "https://www.uniprot.org/uniprotkb/M9PJN5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "M9PJN5", "url": "https://www.uniprot.org/uniprotkb/M9PJN5" } ], "pmid": "" }, { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "M9PJN5", "url": "https://www.uniprot.org/uniprotkb/M9PJN5" } ], "pmid": "" }, { "name": "protein lysine deacetylase activity", "id": "GO:0033558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033558", "evidence": [ { "database": "UniProtKB", "id": "M9PJN5", "url": "https://www.uniprot.org/uniprotkb/M9PJN5" } ], "pmid": "" }, { "name": "histone H4K16 deacetylase activity, hydrolytic mechanism", "id": "GO:0034739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034739", "evidence": [ { "database": "UniProtKB", "id": "M9PJN5", "url": "https://www.uniprot.org/uniprotkb/M9PJN5" } ], "pmid": "" }, { "name": "histone H4K5 deacetylase activity, hydrolytic mechanism", "id": "GO:0180032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180032", "evidence": [ { "database": "UniProtKB", "id": "M9PJN5", "url": "https://www.uniprot.org/uniprotkb/M9PJN5" } ], "pmid": "" }, { "name": "histone H4K8 deacetylase activity, hydrolytic mechanism", "id": "GO:0180033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180033", "evidence": [ { "database": "UniProtKB", "id": "M9PJN5", "url": "https://www.uniprot.org/uniprotkb/M9PJN5" } ], "pmid": "" }, { "name": "histone H4K12 deacetylase activity, hydrolytic mechanism", "id": "GO:0140937", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140937", "evidence": [ { "database": "UniProtKB", "id": "M9PJN5", "url": "https://www.uniprot.org/uniprotkb/M9PJN5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PJN5-1", "start_pos": "857", "end_pos": "857", "site_lbl": "Thr857", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 857, "start_aa": "Thr", "end_pos": 857, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr857", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9PJN5-1" }, { "uniprot_canonical_ac": "M9NEL0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NEL0", "url": "https://www.uniprot.org/uniprotkb/M9NEL0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 131, "chemical_mass": 14506.0, "gene_names": "Dmel\\CG43052;CG43052;Dmel\\CG43052;Dmel_CG43052;MB6.chr2L.pasa.1468", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9NEL0-1" }, { "uniprot_canonical_ac": "M9NFE3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NFE3", "url": "https://www.uniprot.org/uniprotkb/M9NFE3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 97, "chemical_mass": 10989.0, "gene_names": "Dmel\\CG43082;CG43082;Dmel\\CG43082;Dmel_CG43082", "protein_name": "DUF19 domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9NFE3-1" }, { "uniprot_canonical_ac": "M9PBB4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PBB4", "url": "https://www.uniprot.org/uniprotkb/M9PBB4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 622, "chemical_mass": 67904.0, "gene_names": "NimC1;BG:DS00180.10;CG8942;CT25688;Dmel\\CG8942;Dmel_CG8942;NimC1;NimC;Nim;P1;nimC1;nimrod C1;nimrod", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M9PBB4", "url": "https://www.uniprot.org/uniprotkb/M9PBB4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "M9PBB4", "url": "https://www.uniprot.org/uniprotkb/M9PBB4" } ], "pmid": "" } ], "biological_process": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "M9PBB4", "url": "https://www.uniprot.org/uniprotkb/M9PBB4" } ], "pmid": "" }, { "name": "phagocytosis", "id": "GO:0006909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006909", "evidence": [ { "database": "UniProtKB", "id": "M9PBB4", "url": "https://www.uniprot.org/uniprotkb/M9PBB4" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "M9PBB4", "url": "https://www.uniprot.org/uniprotkb/M9PBB4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PBB4-1", "start_pos": "132", "end_pos": "132", "site_lbl": "Thr132", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 132, "start_aa": "Thr", "end_pos": 132, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr132", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9PBB4-1" }, { "uniprot_canonical_ac": "Q94515-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q94515", "url": "https://www.uniprot.org/uniprotkb/Q94515" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 321, "chemical_mass": 37213.0, "gene_names": "ifc;CG9078;DES-1;Des-1;Des1;Dmel\\CG9078;Dmel_CG9078;Ifc;des-1;des1;des;ifc;l(2)26Ab;l(2)gdh-2;ms(2)04875", "protein_name": "Sphingolipid delta(4)-desaturase DES1", "disease": [ { "disease_id": "DOID:0060786", "name": "hypomyelinating leukodystrophy", "description": "A leukodystrophy characterized by improper formation of the myelin sheath in the central nervous system resulting in T2 hyperintensity and variable T1 signal on magnetic resonance imaging.", "url": "https://disease-ontology.org/term/DOID:0060786", "evidence": [ { "id": "0060786", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060786" } ], "weight": 0.0 }, { "disease_id": "DOID:0070399", "name": "hypomyelinating leukodystrophy 18", "description": "A hypomyelinating leukodystrophy characterized by onset of global developmental delay in infancy or early childhood that has_material_basis_in homozygous or compound heterozygous mutation in the DEGS1 gene on chromosome 1q42.", "url": "https://disease-ontology.org/term/DOID:0070399", "evidence": [ { "id": "0070399", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070399" } ], "weight": 0.0 }, { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q94515", "url": "https://www.uniprot.org/uniprotkb/Q94515" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q94515", "url": "https://www.uniprot.org/uniprotkb/Q94515" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q94515", "url": "https://www.uniprot.org/uniprotkb/Q94515" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "Q94515", "url": "https://www.uniprot.org/uniprotkb/Q94515" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q94515", "url": "https://www.uniprot.org/uniprotkb/Q94515" } ], "pmid": "" } ], "biological_process": [ { "name": "ceramide biosynthetic process", "id": "GO:0046513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046513", "evidence": [ { "database": "UniProtKB", "id": "Q94515", "url": "https://www.uniprot.org/uniprotkb/Q94515" } ], "pmid": "" }, { "name": "negative regulation of lipophagy", "id": "GO:1904503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904503", "evidence": [ { "database": "UniProtKB", "id": "Q94515", "url": "https://www.uniprot.org/uniprotkb/Q94515" } ], "pmid": "" }, { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "Q94515", "url": "https://www.uniprot.org/uniprotkb/Q94515" } ], "pmid": "" } ], "molecular_function": [ { "name": "sphingolipid delta-4 desaturase activity", "id": "GO:0042284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042284", "evidence": [ { "database": "UniProtKB", "id": "Q94515", "url": "https://www.uniprot.org/uniprotkb/Q94515" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q94515-1" }, { "uniprot_canonical_ac": "M9PC99-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PC99", "url": "https://www.uniprot.org/uniprotkb/M9PC99" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1231, "chemical_mass": 133753.0, "gene_names": "Sec24CD;BcDNA:LP05220;CG10882;Dmel\\CG10882;Dmel_CG10882;FBgn0031408;Gho;Sec24CD;Sec24;Sten;gho;sec24;sfb3;sten", "protein_name": "", "disease": [ { "disease_id": "DOID:0060438", "name": "Cole-Carpenter syndrome", "description": "An osteogenesis imperfecta characterized by craniosynostosis, communicating hydrocephalus, ocular proptosis, marked postnatal growth failure, and distinctive facial appearance.", "url": "https://disease-ontology.org/term/DOID:0060438", "evidence": [ { "id": "0060438", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060438" } ], "weight": 0.0 } ], "biological_process": [ { "name": "COPII-coated vesicle cargo loading", "id": "GO:0090110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090110", "evidence": [ { "database": "UniProtKB", "id": "M9PC99", "url": "https://www.uniprot.org/uniprotkb/M9PC99" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "M9PC99", "url": "https://www.uniprot.org/uniprotkb/M9PC99" } ], "pmid": "" }, { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "M9PC99", "url": "https://www.uniprot.org/uniprotkb/M9PC99" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "M9PC99", "url": "https://www.uniprot.org/uniprotkb/M9PC99" } ], "pmid": "" }, { "name": "protein secretion", "id": "GO:0009306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009306", "evidence": [ { "database": "UniProtKB", "id": "M9PC99", "url": "https://www.uniprot.org/uniprotkb/M9PC99" } ], "pmid": "" }, { "name": "protein localization to cell surface", "id": "GO:0034394", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034394", "evidence": [ { "database": "UniProtKB", "id": "M9PC99", "url": "https://www.uniprot.org/uniprotkb/M9PC99" } ], "pmid": "" }, { "name": "positive regulation of ER to Golgi vesicle-mediated transport", "id": "GO:1902953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902953", "evidence": [ { "database": "UniProtKB", "id": "M9PC99", "url": "https://www.uniprot.org/uniprotkb/M9PC99" } ], "pmid": "" }, { "name": "positive regulation of protein exit from endoplasmic reticulum", "id": "GO:0070863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070863", "evidence": [ { "database": "UniProtKB", "id": "M9PC99", "url": "https://www.uniprot.org/uniprotkb/M9PC99" } ], "pmid": "" }, { "name": "extracellular matrix constituent secretion", "id": "GO:0070278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070278", "evidence": [ { "database": "UniProtKB", "id": "M9PC99", "url": "https://www.uniprot.org/uniprotkb/M9PC99" } ], "pmid": "" }, { "name": "lumen formation, open tracheal system", "id": "GO:0035149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035149", "evidence": [ { "database": "UniProtKB", "id": "M9PC99", "url": "https://www.uniprot.org/uniprotkb/M9PC99" } ], "pmid": "" }, { "name": "regulation of tube size, open tracheal system", "id": "GO:0035151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035151", "evidence": [ { "database": "UniProtKB", "id": "M9PC99", "url": "https://www.uniprot.org/uniprotkb/M9PC99" } ], "pmid": "" }, { "name": "regulation of tube diameter, open tracheal system", "id": "GO:0035158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035158", "evidence": [ { "database": "UniProtKB", "id": "M9PC99", "url": "https://www.uniprot.org/uniprotkb/M9PC99" } ], "pmid": "" }, { "name": "chitin-based cuticle development", "id": "GO:0040003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040003", "evidence": [ { "database": "UniProtKB", "id": "M9PC99", "url": "https://www.uniprot.org/uniprotkb/M9PC99" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "M9PC99", "url": "https://www.uniprot.org/uniprotkb/M9PC99" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "M9PC99", "url": "https://www.uniprot.org/uniprotkb/M9PC99" } ], "pmid": "" }, { "name": "endoplasmic reticulum exit site", "id": "GO:0070971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070971", "evidence": [ { "database": "UniProtKB", "id": "M9PC99", "url": "https://www.uniprot.org/uniprotkb/M9PC99" } ], "pmid": "" }, { "name": "COPII vesicle coat", "id": "GO:0030127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030127", "evidence": [ { "database": "UniProtKB", "id": "M9PC99", "url": "https://www.uniprot.org/uniprotkb/M9PC99" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "M9PC99", "url": "https://www.uniprot.org/uniprotkb/M9PC99" } ], "pmid": "" }, { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "M9PC99", "url": "https://www.uniprot.org/uniprotkb/M9PC99" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PC99-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Thr142", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 142, "start_aa": "Thr", "end_pos": 142, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr142", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PC99-1", "start_pos": "188", "end_pos": "188", "site_lbl": "Thr188", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 188, "start_aa": "Thr", "end_pos": 188, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr188", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PC99-1", "start_pos": "252", "end_pos": "252", "site_lbl": "Thr252", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 252, "start_aa": "Thr", "end_pos": 252, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr252", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PC99-1", "start_pos": "63", "end_pos": "63", "site_lbl": "Thr63", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 63, "start_aa": "Thr", "end_pos": 63, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr63", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9PC99-1" }, { "uniprot_canonical_ac": "M9PCW4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PCW4", "url": "https://www.uniprot.org/uniprotkb/M9PCW4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 368, "chemical_mass": 43318.0, "gene_names": "Dmel\\CG44004;CG34252;CG44004;Dmel\\CG44004;Dmel_CG44004", "protein_name": "F-box domain-containing protein", "disease": [], "molecular_function": [ { "name": "SCF ubiquitin ligase complex binding", "id": "GO:1905761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905761", "evidence": [ { "database": "UniProtKB", "id": "M9PCW4", "url": "https://www.uniprot.org/uniprotkb/M9PCW4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PCW4-1" }, { "uniprot_canonical_ac": "M9PDC4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PDC4", "url": "https://www.uniprot.org/uniprotkb/M9PDC4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 299, "chemical_mass": 33117.0, "gene_names": "MESR3;CG15162;Dmel\\CG15162;Dmel_CG15162;MESR3", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PDC4", "url": "https://www.uniprot.org/uniprotkb/M9PDC4" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "M9PDC4", "url": "https://www.uniprot.org/uniprotkb/M9PDC4" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "M9PDC4", "url": "https://www.uniprot.org/uniprotkb/M9PDC4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "M9PDC4", "url": "https://www.uniprot.org/uniprotkb/M9PDC4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "M9PDC4", "url": "https://www.uniprot.org/uniprotkb/M9PDC4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PDC4-1" }, { "uniprot_canonical_ac": "M9PFI7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PFI7", "url": "https://www.uniprot.org/uniprotkb/M9PFI7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 49, "chemical_mass": 5146.0, "gene_names": "Dmel\\CG43680;CG43680;Dmel\\CG43680;Dmel_CG43680", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PFI7-1" }, { "uniprot_canonical_ac": "M9PFX4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PFX4", "url": "https://www.uniprot.org/uniprotkb/M9PFX4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1231, "chemical_mass": 122673.0, "gene_names": "Cpr76Bd;CG9299;Cpr76Bd;DmelCpr76Bd;Dmel\\CG9299;Dmel_CG9299", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "M9PFX4", "url": "https://www.uniprot.org/uniprotkb/M9PFX4" } ], "pmid": "" }, { "name": "chitin-based extracellular matrix", "id": "GO:0062129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062129", "evidence": [ { "database": "UniProtKB", "id": "M9PFX4", "url": "https://www.uniprot.org/uniprotkb/M9PFX4" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of chitin-based larval cuticle", "id": "GO:0008010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008010", "evidence": [ { "database": "UniProtKB", "id": "M9PFX4", "url": "https://www.uniprot.org/uniprotkb/M9PFX4" } ], "pmid": "" } ], "biological_process": [ { "name": "chitin-based cuticle development", "id": "GO:0040003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040003", "evidence": [ { "database": "UniProtKB", "id": "M9PFX4", "url": "https://www.uniprot.org/uniprotkb/M9PFX4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PFX4-1", "start_pos": "254", "end_pos": "254", "site_lbl": "Thr254", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 254, "start_aa": "Thr", "end_pos": 254, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr254", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "M9PFX4", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=M9PFX4" } ] } ] }, { "uniprot_canonical_ac": "M9PFX4-1", "start_pos": "355", "end_pos": "355", "site_lbl": "Ser355", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 355, "start_aa": "Ser", "end_pos": 355, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser355", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "M9PFX4", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=M9PFX4" } ] } ] }, { "uniprot_canonical_ac": "M9PFX4-1", "start_pos": "464", "end_pos": "464", "site_lbl": "Ser464", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 464, "start_aa": "Ser", "end_pos": 464, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser464", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "M9PFX4", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=M9PFX4" } ] } ] }, { "uniprot_canonical_ac": "M9PFX4-1", "start_pos": "604", "end_pos": "604", "site_lbl": "Thr604", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 604, "start_aa": "Thr", "end_pos": 604, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr604", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "M9PFX4", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=M9PFX4" } ] } ] } ], "record_id": "M9PFX4-1" }, { "uniprot_canonical_ac": "M9PG65-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PG65", "url": "https://www.uniprot.org/uniprotkb/M9PG65" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 150, "chemical_mass": 17078.0, "gene_names": "Sfp78E;CG42607;Dmel\\CG42607;Dmel_CG42607;Sfp78E", "protein_name": "", "disease": [], "biological_process": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "M9PG65", "url": "https://www.uniprot.org/uniprotkb/M9PG65" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "M9PG65", "url": "https://www.uniprot.org/uniprotkb/M9PG65" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PG65-1" }, { "uniprot_canonical_ac": "M9PG98-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PG98", "url": "https://www.uniprot.org/uniprotkb/M9PG98" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1004, "chemical_mass": 114263.0, "gene_names": "Edem1;CG3810;DM-pI;Dmel\\CG3810;Dmel_CG3810;EDEM1;EG.86E4.2;EG:86E4.2;Edem1;dEDEM1;edem1", "protein_name": "alpha-1,2-Mannosidase", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "M9PG98", "url": "https://www.uniprot.org/uniprotkb/M9PG98" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "M9PG98", "url": "https://www.uniprot.org/uniprotkb/M9PG98" } ], "pmid": "" }, { "name": "endoplasmic reticulum quality control compartment", "id": "GO:0044322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044322", "evidence": [ { "database": "UniProtKB", "id": "M9PG98", "url": "https://www.uniprot.org/uniprotkb/M9PG98" } ], "pmid": "" } ], "biological_process": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "M9PG98", "url": "https://www.uniprot.org/uniprotkb/M9PG98" } ], "pmid": "" }, { "name": "endoplasmic reticulum unfolded protein response", "id": "GO:0030968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030968", "evidence": [ { "database": "UniProtKB", "id": "M9PG98", "url": "https://www.uniprot.org/uniprotkb/M9PG98" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "M9PG98", "url": "https://www.uniprot.org/uniprotkb/M9PG98" } ], "pmid": "" }, { "name": "endoplasmic reticulum mannose trimming", "id": "GO:1904380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904380", "evidence": [ { "database": "UniProtKB", "id": "M9PG98", "url": "https://www.uniprot.org/uniprotkb/M9PG98" } ], "pmid": "" }, { "name": "positive regulation of retrograde protein transport, ER to cytosol", "id": "GO:1904154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904154", "evidence": [ { "database": "UniProtKB", "id": "M9PG98", "url": "https://www.uniprot.org/uniprotkb/M9PG98" } ], "pmid": "" }, { "name": "determination of adult lifespan", "id": "GO:0008340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008340", "evidence": [ { "database": "UniProtKB", "id": "M9PG98", "url": "https://www.uniprot.org/uniprotkb/M9PG98" } ], "pmid": "" }, { "name": "ubiquitin-dependent glycoprotein ERAD pathway", "id": "GO:0097466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097466", "evidence": [ { "database": "UniProtKB", "id": "M9PG98", "url": "https://www.uniprot.org/uniprotkb/M9PG98" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "M9PG98", "url": "https://www.uniprot.org/uniprotkb/M9PG98" } ], "pmid": "" }, { "name": "mannosyl-oligosaccharide 1,2-alpha-mannosidase activity", "id": "GO:0004571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004571", "evidence": [ { "database": "UniProtKB", "id": "M9PG98", "url": "https://www.uniprot.org/uniprotkb/M9PG98" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PG98-1" }, { "uniprot_canonical_ac": "Q8IQX8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQX8", "url": "https://www.uniprot.org/uniprotkb/Q8IQX8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 564, "chemical_mass": 62361.0, "gene_names": "HisRS;Aats-his;CG6335;Dmel\\CG6335;Dmel_CG6335;HRS;Harsl;HisRS;dHARS;l(1)G0165;l(1)G0358", "protein_name": "histidine--tRNA ligase", "disease": [ { "disease_id": "DOID:0050857", "name": "Perrault syndrome", "description": "A syndrome that is characterized by sensorineural hearing loss and ovarian failure.", "url": "https://disease-ontology.org/term/DOID:0050857", "evidence": [ { "id": "0050857", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050857" } ], "weight": 0.0 }, { "disease_id": "DOID:0061117", "name": "Perrault syndrome 2", "description": "A Perrault syndrome that is characterized by sensorineural deafness in both males and females that has_material_basis_in compound heterozygous mutation in the HARS2 gene on chromosome 5q31.", "url": "https://disease-ontology.org/term/DOID:0061117", "evidence": [ { "id": "0061117", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061117" } ], "weight": 0.0 }, { "disease_id": "DOID:0110162", "name": "Charcot-Marie-Tooth disease, axonal type 2W", "description": "A Charcot-Marie-Tooth disease type 2 that has_material_basis_in heterozygous mutation in the HARS gene on chromosome 5q31.", "url": "https://disease-ontology.org/term/DOID:0110162", "evidence": [ { "id": "0110162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110162" } ], "weight": 0.0 }, { "disease_id": "DOID:0110842", "name": "Usher syndrome type 3B", "description": "An Usher syndrome type 3 that has_material_basis_in homozygous mutation in the HARS gene on chromosome 5q31.", "url": "https://disease-ontology.org/term/DOID:0110842", "evidence": [ { "id": "0110842", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110842" } ], "weight": 0.0 }, { "disease_id": "DOID:2491", "name": "sensory peripheral neuropathy", "description": "A neuropathy that involves damage to sensory nerves of the peripheral nervous system.", "url": "https://disease-ontology.org/term/DOID:2491", "evidence": [ { "id": "2491", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2491" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q8IQX8", "url": "https://www.uniprot.org/uniprotkb/Q8IQX8" } ], "pmid": "" }, { "name": "histidine-tRNA ligase activity", "id": "GO:0004821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004821", "evidence": [ { "database": "UniProtKB", "id": "Q8IQX8", "url": "https://www.uniprot.org/uniprotkb/Q8IQX8" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q8IQX8", "url": "https://www.uniprot.org/uniprotkb/Q8IQX8" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q8IQX8", "url": "https://www.uniprot.org/uniprotkb/Q8IQX8" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q8IQX8", "url": "https://www.uniprot.org/uniprotkb/Q8IQX8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q8IQX8", "url": "https://www.uniprot.org/uniprotkb/Q8IQX8" } ], "pmid": "" } ], "biological_process": [ { "name": "histidyl-tRNA aminoacylation", "id": "GO:0006427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006427", "evidence": [ { "database": "UniProtKB", "id": "Q8IQX8", "url": "https://www.uniprot.org/uniprotkb/Q8IQX8" } ], "pmid": "" }, { "name": "mitochondrial translation", "id": "GO:0032543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032543", "evidence": [ { "database": "UniProtKB", "id": "Q8IQX8", "url": "https://www.uniprot.org/uniprotkb/Q8IQX8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IQX8-1" }, { "uniprot_canonical_ac": "M9PHZ1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PHZ1", "url": "https://www.uniprot.org/uniprotkb/M9PHZ1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 588, "chemical_mass": 63640.0, "gene_names": "Ada3;ADA3;Ada3;CG7098;DADA3;Dmel\\CG7098;Dmel_CG7098;HL-XIV;ada3;dADA3;dAda3;dik", "protein_name": "", "disease": [], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "M9PHZ1", "url": "https://www.uniprot.org/uniprotkb/M9PHZ1" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "M9PHZ1", "url": "https://www.uniprot.org/uniprotkb/M9PHZ1" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PHZ1", "url": "https://www.uniprot.org/uniprotkb/M9PHZ1" } ], "pmid": "" }, { "name": "histone acetyltransferase complex", "id": "GO:0000123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000123", "evidence": [ { "database": "UniProtKB", "id": "M9PHZ1", "url": "https://www.uniprot.org/uniprotkb/M9PHZ1" } ], "pmid": "" }, { "name": "SAGA complex", "id": "GO:0000124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000124", "evidence": [ { "database": "UniProtKB", "id": "M9PHZ1", "url": "https://www.uniprot.org/uniprotkb/M9PHZ1" } ], "pmid": "" }, { "name": "H3 histone acetyltransferase complex", "id": "GO:0070775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070775", "evidence": [ { "database": "UniProtKB", "id": "M9PHZ1", "url": "https://www.uniprot.org/uniprotkb/M9PHZ1" } ], "pmid": "" }, { "name": "polytene chromosome", "id": "GO:0005700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005700", "evidence": [ { "database": "UniProtKB", "id": "M9PHZ1", "url": "https://www.uniprot.org/uniprotkb/M9PHZ1" } ], "pmid": "" }, { "name": "polytene chromosome puff", "id": "GO:0005703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005703", "evidence": [ { "database": "UniProtKB", "id": "M9PHZ1", "url": "https://www.uniprot.org/uniprotkb/M9PHZ1" } ], "pmid": "" }, { "name": "ATAC complex", "id": "GO:0140672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140672", "evidence": [ { "database": "UniProtKB", "id": "M9PHZ1", "url": "https://www.uniprot.org/uniprotkb/M9PHZ1" } ], "pmid": "" } ], "biological_process": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "M9PHZ1", "url": "https://www.uniprot.org/uniprotkb/M9PHZ1" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "M9PHZ1", "url": "https://www.uniprot.org/uniprotkb/M9PHZ1" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "M9PHZ1", "url": "https://www.uniprot.org/uniprotkb/M9PHZ1" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "M9PHZ1", "url": "https://www.uniprot.org/uniprotkb/M9PHZ1" } ], "pmid": "" }, { "name": "transcription initiation-coupled chromatin remodeling", "id": "GO:0045815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045815", "evidence": [ { "database": "UniProtKB", "id": "M9PHZ1", "url": "https://www.uniprot.org/uniprotkb/M9PHZ1" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "M9PHZ1", "url": "https://www.uniprot.org/uniprotkb/M9PHZ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PHZ1-1" }, { "uniprot_canonical_ac": "M9PI14-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PI14", "url": "https://www.uniprot.org/uniprotkb/M9PI14" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 180, "chemical_mass": 21198.0, "gene_names": "Naa20A;CG14222;DmAAF48987;Dmel\\CG14222;Dmel_CG14222;NAA20;Naa20A;Naa20;dNAA20", "protein_name": "N-alpha-acetyltransferase 20", "disease": [ { "disease_id": "DOID:0081233", "name": "autosomal recessive intellectual developmental disorder 73", "description": "An autosomal recessive intellectual developmental disorder that is characterized by global developmental delay with hypotonia and mildly delayed walking, impaired intellectual development with poor or absent speech, and mildly dysmorphic features and that has_material_basis_in homozygous mutation in the NAA20 gene on chromosome 20p11.", "url": "https://disease-ontology.org/term/DOID:0081233", "evidence": [ { "id": "0081233", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081233" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PI14", "url": "https://www.uniprot.org/uniprotkb/M9PI14" } ], "pmid": "" }, { "name": "NatB complex", "id": "GO:0031416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031416", "evidence": [ { "database": "UniProtKB", "id": "M9PI14", "url": "https://www.uniprot.org/uniprotkb/M9PI14" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9PI14", "url": "https://www.uniprot.org/uniprotkb/M9PI14" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "M9PI14", "url": "https://www.uniprot.org/uniprotkb/M9PI14" } ], "pmid": "" }, { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "M9PI14", "url": "https://www.uniprot.org/uniprotkb/M9PI14" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-N-terminal amino-acid acetyltransferase activity", "id": "GO:0004596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004596", "evidence": [ { "database": "UniProtKB", "id": "M9PI14", "url": "https://www.uniprot.org/uniprotkb/M9PI14" } ], "pmid": "" }, { "name": "protein N-terminal-methionine acetyltransferase activity", "id": "GO:0120518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120518", "evidence": [ { "database": "UniProtKB", "id": "M9PI14", "url": "https://www.uniprot.org/uniprotkb/M9PI14" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PI14-1" }, { "uniprot_canonical_ac": "M9PI45-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PI45", "url": "https://www.uniprot.org/uniprotkb/M9PI45" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 682, "chemical_mass": 71304.0, "gene_names": "mirr;CG10601;DH1;De1;De3;Dmel\\CG10601;Dmel_CG10601;Group F;IRO-C;Iro-C;IroC;Iro;MIRR;Mirr;Mrr;Sai;crep;cre;group F;iro-C;iro;l(3)69Ca;l(3)69Da;l(3)6D1;l(3)A5-3-42;mirr;mir;mrr", "protein_name": "", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "M9PI45", "url": "https://www.uniprot.org/uniprotkb/M9PI45" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "M9PI45", "url": "https://www.uniprot.org/uniprotkb/M9PI45" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "M9PI45", "url": "https://www.uniprot.org/uniprotkb/M9PI45" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "M9PI45", "url": "https://www.uniprot.org/uniprotkb/M9PI45" } ], "pmid": "" }, { "name": "peripheral nervous system development", "id": "GO:0007422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007422", "evidence": [ { "database": "UniProtKB", "id": "M9PI45", "url": "https://www.uniprot.org/uniprotkb/M9PI45" } ], "pmid": "" }, { "name": "cell development", "id": "GO:0048468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048468", "evidence": [ { "database": "UniProtKB", "id": "M9PI45", "url": "https://www.uniprot.org/uniprotkb/M9PI45" } ], "pmid": "" }, { "name": "sensory neuron axon guidance", "id": "GO:0097374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097374", "evidence": [ { "database": "UniProtKB", "id": "M9PI45", "url": "https://www.uniprot.org/uniprotkb/M9PI45" } ], "pmid": "" }, { "name": "negative regulation of growth", "id": "GO:0045926", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045926", "evidence": [ { "database": "UniProtKB", "id": "M9PI45", "url": "https://www.uniprot.org/uniprotkb/M9PI45" } ], "pmid": "" }, { "name": "muscle cell fate commitment", "id": "GO:0042693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042693", "evidence": [ { "database": "UniProtKB", "id": "M9PI45", "url": "https://www.uniprot.org/uniprotkb/M9PI45" } ], "pmid": "" }, { "name": "embryonic development via the syncytial blastoderm", "id": "GO:0001700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001700", "evidence": [ { "database": "UniProtKB", "id": "M9PI45", "url": "https://www.uniprot.org/uniprotkb/M9PI45" } ], "pmid": "" }, { "name": "compound eye morphogenesis", "id": "GO:0001745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001745", "evidence": [ { "database": "UniProtKB", "id": "M9PI45", "url": "https://www.uniprot.org/uniprotkb/M9PI45" } ], "pmid": "" }, { "name": "imaginal disc-derived wing vein specification", "id": "GO:0007474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007474", "evidence": [ { "database": "UniProtKB", "id": "M9PI45", "url": "https://www.uniprot.org/uniprotkb/M9PI45" } ], "pmid": "" }, { "name": "imaginal disc-derived wing morphogenesis", "id": "GO:0007476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007476", "evidence": [ { "database": "UniProtKB", "id": "M9PI45", "url": "https://www.uniprot.org/uniprotkb/M9PI45" } ], "pmid": "" }, { "name": "equator specification", "id": "GO:0045317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045317", "evidence": [ { "database": "UniProtKB", "id": "M9PI45", "url": "https://www.uniprot.org/uniprotkb/M9PI45" } ], "pmid": "" }, { "name": "dorsal appendage formation", "id": "GO:0046843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046843", "evidence": [ { "database": "UniProtKB", "id": "M9PI45", "url": "https://www.uniprot.org/uniprotkb/M9PI45" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PI45", "url": "https://www.uniprot.org/uniprotkb/M9PI45" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "M9PI45", "url": "https://www.uniprot.org/uniprotkb/M9PI45" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "M9PI45", "url": "https://www.uniprot.org/uniprotkb/M9PI45" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "M9PI45", "url": "https://www.uniprot.org/uniprotkb/M9PI45" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "M9PI45", "url": "https://www.uniprot.org/uniprotkb/M9PI45" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PI45-1" }, { "uniprot_canonical_ac": "M9PI57-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PI57", "url": "https://www.uniprot.org/uniprotkb/M9PI57" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 834, "chemical_mass": 96325.0, "gene_names": "nan;CG5842;CT18317;DmNan;Dmel\\CG5842;Dmel_CG5842;Iav;NAN;Nan;OCR;TRPV;nan", "protein_name": "", "disease": [ { "disease_id": "DOID:0050534", "name": "congenital stationary night blindness", "description": "A hereditary night blindness that is characterized by hemeralopia with a moderate loss of visual acuity and caused by defective photoreceptor-to-bipolar cell signaling with common ERG findings of reduced or absent b-waves and generally normal a-waves.", "url": "https://disease-ontology.org/term/DOID:0050534", "evidence": [ { "id": "0050534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050534" } ], "weight": 0.0 }, { "disease_id": "DOID:0070355", "name": "overactive bladder syndrome", "description": "A bladder disease characterized by urinary urgency without urinary tract infection or obvious pathology, usually accompanied by urinary frequency and nocturia.", "url": "https://disease-ontology.org/term/DOID:0070355", "evidence": [ { "id": "0070355", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070355" } ], "weight": 0.0 }, { "disease_id": "DOID:0110182", "name": "Charcot-Marie-Tooth disease axonal type 2C", "description": "A Charcot-Marie-Tooth disease type 2 that has_material_basis_in heterozygous mutation in the TRPV4 gene on chromosome 12q24.", "url": "https://disease-ontology.org/term/DOID:0110182", "evidence": [ { "id": "0110182", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110182" } ], "weight": 0.0 }, { "disease_id": "DOID:0110555", "name": "autosomal dominant nonsyndromic deafness 25", "description": "An autosomal dominant nonsyndromic deafness that is characterized by postlingual onset in the second-sixth decade of life with high frequency progressive hearing loss and has_material_basis_in mutation in the SLC17A8 gene on chromosome 12q23.", "url": "https://disease-ontology.org/term/DOID:0110555", "evidence": [ { "id": "0110555", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110555" } ], "weight": 0.0 }, { "disease_id": "DOID:0111215", "name": "autosomal dominant distal hereditary motor neuronopathy 8", "description": "An autosomal dominant distal hereditary motor neuronopathy that is characterized by congenital, non-progressive, predominantly distal, lower limb muscle weakness and atrophy with variable severity that has_material_basis_in heterozygous mutation in the TRPV4 gene on 12q24.11.", "url": "https://disease-ontology.org/term/DOID:0111215", "evidence": [ { "id": "0111215", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111215" } ], "weight": 0.0 }, { "disease_id": "DOID:0111514", "name": "metatropic dysplasia", "description": "A spondyloepimetaphyseal dysplasia characterized by short limbs with limitation and enlargement of joints, usually severe and progressive kyphoscoliosis, severe platyspondyly, and severe metaphyseal enlargement that has_material_basis_in heterozygous mutation in the TRPV4 gene on chromosome 12q24.11.", "url": "https://disease-ontology.org/term/DOID:0111514", "evidence": [ { "id": "0111514", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111514" } ], "weight": 0.0 }, { "disease_id": "DOID:0111539", "name": "parastremmatic dwarfism", "description": "An osteochondrodysplasia characterized by severe dwarfism, kyphoscoliosis, stiffness of large joints and bowing and twisting of lower limbs that has_material_basis_in heterozygous mutation in the TRPV4 gene on chromosome 12q24.11.", "url": "https://disease-ontology.org/term/DOID:0111539", "evidence": [ { "id": "0111539", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111539" } ], "weight": 0.0 }, { "disease_id": "DOID:0111552", "name": "scapuloperoneal spinal muscular atrophy", "description": "A motor neuron disease characterized by progressive scapuloperoneal atrophy and weakness, laryngeal palsy, congenital absence of muscles and in some cases developmental abnormalities of the bones that has_material_basis_in heterozygous mutation in the TRPV4 gene on chromosome 12q24.11.", "url": "https://disease-ontology.org/term/DOID:0111552", "evidence": [ { "id": "0111552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111552" } ], "weight": 0.0 }, { "disease_id": "DOID:0111553", "name": "spondyloepiphyseal dysplasia Maroteaux type", "description": "An osteochondrodysplasia characterized by dysplastic epiphyses, short stature appearing in infancy, short neck, short and stubby hands and feet, platyspondyly, severe brachydactyly, and pelvic abnormalities that has_material_basis_in heterozygous mutation in the TRPV4 gene on chromosome 12q24.11.", "url": "https://disease-ontology.org/term/DOID:0111553", "evidence": [ { "id": "0111553", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111553" } ], "weight": 0.0 }, { "disease_id": "DOID:0111554", "name": "spondylometaphyseal dysplasia Kozlowski type", "description": "A spondylometaphyseal dysplasia characterized by vetebral platyspondyly and overfaced pedicles, scoliosis, and mild metaphyseal abnormalities in the pelvis that has_material_basis_in heterozygous mutation in the TRPV4 gene on chromosome 12q24.11.", "url": "https://disease-ontology.org/term/DOID:0111554", "evidence": [ { "id": "0111554", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111554" } ], "weight": 0.0 }, { "disease_id": "DOID:0111711", "name": "focal nonepidermolytic palmoplantar keratoderma 2", "description": "A focal nonepidermolytic palmoplantar keratoderma that has_material_basis_in heterozygous mutation in the TRPV3 gene on chromosome 17p13.2.", "url": "https://disease-ontology.org/term/DOID:0111711", "evidence": [ { "id": "0111711", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111711" } ], "weight": 0.0 }, { "disease_id": "DOID:0112013", "name": "autosomal dominant mutilating palmoplantar keratoderma with periorificial keratotic plaques", "description": "A mutilating palmoplantar keratoderma with periorificial keratotic plaques that has_material_basis_in heterozygous mutation in the TRPV3 gene on chromosome 17p13.2.", "url": "https://disease-ontology.org/term/DOID:0112013", "evidence": [ { "id": "0112013", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112013" } ], "weight": 0.0 }, { "disease_id": "DOID:10024", "name": "migraine with aura", "description": "A migraine characterized by migraine headache which is preceded or accompanied by a transient focal neurological phenomenon.", "url": "https://disease-ontology.org/term/DOID:10024", "evidence": [ { "id": "10024", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10024" } ], "weight": 0.0 }, { "disease_id": "DOID:10159", "name": "osteonecrosis", "description": "An ischemic bone disease that results_in necrosis located_in bone.", "url": "https://disease-ontology.org/term/DOID:10159", "evidence": [ { "id": "10159", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10159" } ], "weight": 0.0 }, { "disease_id": "DOID:10591", "name": "pre-eclampsia", "description": "A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy.", "url": "https://disease-ontology.org/term/DOID:10591", "evidence": [ { "id": "10591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10591" } ], "weight": 0.0 }, { "disease_id": "DOID:10808", "name": "gastric ulcer", "description": "", "url": "https://disease-ontology.org/term/DOID:10808", "evidence": [ { "id": "10808", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10808" } ], "weight": 0.0 }, { "disease_id": "DOID:11446", "name": "sciatic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:11446", "evidence": [ { "id": "11446", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11446" } ], "weight": 0.0 }, { "disease_id": "DOID:11714", "name": "gestational diabetes", "description": "A diabetes mellitus that manifests during pregnancy.", "url": "https://disease-ontology.org/term/DOID:11714", "evidence": [ { "id": "11714", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11714" } ], "weight": 0.0 }, { "disease_id": "DOID:13543", "name": "hyperparathyroidism", "description": "A parathyroid gland disease characterized by an overactivity of the parathyroid glands, leading to an excess of parathyroid hormone in the body.", "url": "https://disease-ontology.org/term/DOID:13543", "evidence": [ { "id": "13543", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13543" } ], "weight": 0.0 }, { "disease_id": "DOID:2548", "name": "reflex epilepsy", "description": "A variable age at onset electroclinical syndrome that is consistently induced by identifiable and objective-specific triggers, which may be an afferent stimulus or by the patient's own activity.", "url": "https://disease-ontology.org/term/DOID:2548", "evidence": [ { "id": "2548", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2548" } ], "weight": 0.0 }, { "disease_id": "DOID:2723", "name": "dermatitis", "description": "A skin disease characterized by itchy, erythematous, vesicular, weeping and crusting patches of skin.", "url": "https://disease-ontology.org/term/DOID:2723", "evidence": [ { "id": "2723", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2723" } ], "weight": 0.0 }, { "disease_id": "DOID:3310", "name": "atopic dermatitis", "description": "An allergic contact dermatitis that is a chronically relapsing inflammatory allergic response located_in the skin that causes itching and flaking.", "url": "https://disease-ontology.org/term/DOID:3310", "evidence": [ { "id": "3310", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3310" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:6364", "name": "migraine", "description": "A brain disease that is characterized by moderate to severe headaches, nausea, extreme sensitivity to light and sound and intense unilaterial throbbing or pulsing.", "url": "https://disease-ontology.org/term/DOID:6364", "evidence": [ { "id": "6364", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6364" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 }, { "disease_id": "DOID:809", "name": "cocaine abuse", "description": "A substance abuse that involves the recurring use of cocaine despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:809", "evidence": [ { "id": "809", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:809" } ], "weight": 0.0 }, { "disease_id": "DOID:8881", "name": "rosacea", "description": "", "url": "https://disease-ontology.org/term/DOID:8881", "evidence": [ { "id": "8881", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8881" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9743", "name": "diabetic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:9743", "evidence": [ { "id": "9743", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9743" } ], "weight": 0.0 }, { "disease_id": "DOID:987", "name": "alopecia", "description": "A hypotrichosis that is characterized by a loss of hair from the head or body.", "url": "https://disease-ontology.org/term/DOID:987", "evidence": [ { "id": "987", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:987" } ], "weight": 0.0 }, { "disease_id": "DOID:9975", "name": "cocaine dependence", "description": "A drug dependence that is a psychological dependency on the regular use of cocaine.", "url": "https://disease-ontology.org/term/DOID:9975", "evidence": [ { "id": "9975", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9975" } ], "weight": 0.0 } ], "biological_process": [ { "name": "startle response", "id": "GO:0001964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001964", "evidence": [ { "database": "UniProtKB", "id": "M9PI57", "url": "https://www.uniprot.org/uniprotkb/M9PI57" } ], "pmid": "" }, { "name": "mechanosensory behavior", "id": "GO:0007638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007638", "evidence": [ { "database": "UniProtKB", "id": "M9PI57", "url": "https://www.uniprot.org/uniprotkb/M9PI57" } ], "pmid": "" }, { "name": "detection of mechanical stimulus involved in sensory perception of touch", "id": "GO:0050976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050976", "evidence": [ { "database": "UniProtKB", "id": "M9PI57", "url": "https://www.uniprot.org/uniprotkb/M9PI57" } ], "pmid": "" }, { "name": "detection of mechanical stimulus involved in sensory perception of sound", "id": "GO:0050910", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050910", "evidence": [ { "database": "UniProtKB", "id": "M9PI57", "url": "https://www.uniprot.org/uniprotkb/M9PI57" } ], "pmid": "" }, { "name": "calcium ion transport", "id": "GO:0006816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006816", "evidence": [ { "database": "UniProtKB", "id": "M9PI57", "url": "https://www.uniprot.org/uniprotkb/M9PI57" } ], "pmid": "" }, { "name": "monoatomic ion transmembrane transport", "id": "GO:0034220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034220", "evidence": [ { "database": "UniProtKB", "id": "M9PI57", "url": "https://www.uniprot.org/uniprotkb/M9PI57" } ], "pmid": "" }, { "name": "monoatomic cation transport", "id": "GO:0006812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006812", "evidence": [ { "database": "UniProtKB", "id": "M9PI57", "url": "https://www.uniprot.org/uniprotkb/M9PI57" } ], "pmid": "" }, { "name": "adult walking behavior", "id": "GO:0007628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007628", "evidence": [ { "database": "UniProtKB", "id": "M9PI57", "url": "https://www.uniprot.org/uniprotkb/M9PI57" } ], "pmid": "" }, { "name": "response to auditory stimulus", "id": "GO:0010996", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010996", "evidence": [ { "database": "UniProtKB", "id": "M9PI57", "url": "https://www.uniprot.org/uniprotkb/M9PI57" } ], "pmid": "" }, { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "M9PI57", "url": "https://www.uniprot.org/uniprotkb/M9PI57" } ], "pmid": "" }, { "name": "calcium ion transmembrane transport", "id": "GO:0070588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070588", "evidence": [ { "database": "UniProtKB", "id": "M9PI57", "url": "https://www.uniprot.org/uniprotkb/M9PI57" } ], "pmid": "" }, { "name": "detection of mechanical stimulus involved in sensory perception", "id": "GO:0050974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050974", "evidence": [ { "database": "UniProtKB", "id": "M9PI57", "url": "https://www.uniprot.org/uniprotkb/M9PI57" } ], "pmid": "" }, { "name": "neuromuscular process controlling posture", "id": "GO:0050884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050884", "evidence": [ { "database": "UniProtKB", "id": "M9PI57", "url": "https://www.uniprot.org/uniprotkb/M9PI57" } ], "pmid": "" }, { "name": "calcium ion import across plasma membrane", "id": "GO:0098703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098703", "evidence": [ { "database": "UniProtKB", "id": "M9PI57", "url": "https://www.uniprot.org/uniprotkb/M9PI57" } ], "pmid": "" }, { "name": "response to humidity", "id": "GO:0009270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009270", "evidence": [ { "database": "UniProtKB", "id": "M9PI57", "url": "https://www.uniprot.org/uniprotkb/M9PI57" } ], "pmid": "" }, { "name": "negative gravitaxis", "id": "GO:0048060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048060", "evidence": [ { "database": "UniProtKB", "id": "M9PI57", "url": "https://www.uniprot.org/uniprotkb/M9PI57" } ], "pmid": "" }, { "name": "regulation of mechanosensory behavior", "id": "GO:1905790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905790", "evidence": [ { "database": "UniProtKB", "id": "M9PI57", "url": "https://www.uniprot.org/uniprotkb/M9PI57" } ], "pmid": "" } ], "cellular_component": [ { "name": "cation channel complex", "id": "GO:0034703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034703", "evidence": [ { "database": "UniProtKB", "id": "M9PI57", "url": "https://www.uniprot.org/uniprotkb/M9PI57" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M9PI57", "url": "https://www.uniprot.org/uniprotkb/M9PI57" } ], "pmid": "" }, { "name": "calcium channel complex", "id": "GO:0034704", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034704", "evidence": [ { "database": "UniProtKB", "id": "M9PI57", "url": "https://www.uniprot.org/uniprotkb/M9PI57" } ], "pmid": "" } ], "molecular_function": [ { "name": "monoatomic ion channel activity", "id": "GO:0005216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005216", "evidence": [ { "database": "UniProtKB", "id": "M9PI57", "url": "https://www.uniprot.org/uniprotkb/M9PI57" } ], "pmid": "" }, { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "M9PI57", "url": "https://www.uniprot.org/uniprotkb/M9PI57" } ], "pmid": "" }, { "name": "monoatomic cation channel activity", "id": "GO:0005261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005261", "evidence": [ { "database": "UniProtKB", "id": "M9PI57", "url": "https://www.uniprot.org/uniprotkb/M9PI57" } ], "pmid": "" }, { "name": "mechanosensitive monoatomic ion channel activity", "id": "GO:0008381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008381", "evidence": [ { "database": "UniProtKB", "id": "M9PI57", "url": "https://www.uniprot.org/uniprotkb/M9PI57" } ], "pmid": "" }, { "name": "mechanosensitive monoatomic cation channel activity", "id": "GO:0140135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140135", "evidence": [ { "database": "UniProtKB", "id": "M9PI57", "url": "https://www.uniprot.org/uniprotkb/M9PI57" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PI57-1" }, { "uniprot_canonical_ac": "M9PIC9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PIC9", "url": "https://www.uniprot.org/uniprotkb/M9PIC9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1960, "chemical_mass": 223190.0, "gene_names": "Spc105R;CG11451;DmSpc105;Dmel\\CG11451;Dmel_CG11451;KNL1;Spc105-R;Spc105R;Spc105r;Spc105;dmKNL-1;dmSpc105R;spc105R;spc105r", "protein_name": "", "disease": [], "biological_process": [ { "name": "kinetochore assembly", "id": "GO:0051382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051382", "evidence": [ { "database": "UniProtKB", "id": "M9PIC9", "url": "https://www.uniprot.org/uniprotkb/M9PIC9" } ], "pmid": "" }, { "name": "attachment of spindle microtubules to kinetochore", "id": "GO:0008608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008608", "evidence": [ { "database": "UniProtKB", "id": "M9PIC9", "url": "https://www.uniprot.org/uniprotkb/M9PIC9" } ], "pmid": "" } ], "cellular_component": [ { "name": "outer kinetochore", "id": "GO:0000940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000940", "evidence": [ { "database": "UniProtKB", "id": "M9PIC9", "url": "https://www.uniprot.org/uniprotkb/M9PIC9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PIC9-1", "start_pos": "1349", "end_pos": "1349", "site_lbl": "Thr1349", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1349, "start_aa": "Thr", "end_pos": 1349, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1349", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "M9PIC9-1" }, { "uniprot_canonical_ac": "M9PIM3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PIM3", "url": "https://www.uniprot.org/uniprotkb/M9PIM3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1026, "chemical_mass": 118749.0, "gene_names": "Dmel\\CG43968;CG43968;Dmel\\CG43968;Dmel_CG43968;lincRNA.665", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "M9PIM3-1" }, { "uniprot_canonical_ac": "O16043-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "O16043", "url": "https://www.uniprot.org/uniprotkb/O16043" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 183, "chemical_mass": 18823.0, "gene_names": "Df31;BEST:LD04967;CG2207;DF 31;DF31;Df31;Dmel\\CG2207;Dmel_CG2207;LD04967;anon-EST:Liang-1.46;anon-EST:Posey126;anon-EST:fe1A4;anon-WO0153538.53;anon1A4;clone 1.46;l(2)k05815", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "O16043", "url": "https://www.uniprot.org/uniprotkb/O16043" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "O16043", "url": "https://www.uniprot.org/uniprotkb/O16043" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "O16043", "url": "https://www.uniprot.org/uniprotkb/O16043" } ], "pmid": "" } ], "biological_process": [ { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "O16043", "url": "https://www.uniprot.org/uniprotkb/O16043" } ], "pmid": "" }, { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "O16043", "url": "https://www.uniprot.org/uniprotkb/O16043" } ], "pmid": "" } ], "molecular_function": [ { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "O16043", "url": "https://www.uniprot.org/uniprotkb/O16043" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "O16043-1" }, { "uniprot_canonical_ac": "O17452-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "O17452", "url": "https://www.uniprot.org/uniprotkb/O17452" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 230, "chemical_mass": 25492.0, "gene_names": "PeriA;CG17058;CG31559;Dmel\\CG17058;Dmel_CG17058;PeriA;Peritrophin-A;obst-D", "protein_name": "", "disease": [], "biological_process": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "O17452", "url": "https://www.uniprot.org/uniprotkb/O17452" } ], "pmid": "" }, { "name": "chitin-based cuticle development", "id": "GO:0040003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040003", "evidence": [ { "database": "UniProtKB", "id": "O17452", "url": "https://www.uniprot.org/uniprotkb/O17452" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "O17452", "url": "https://www.uniprot.org/uniprotkb/O17452" } ], "pmid": "" }, { "name": "external encapsulating structure", "id": "GO:0030312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030312", "evidence": [ { "database": "UniProtKB", "id": "O17452", "url": "https://www.uniprot.org/uniprotkb/O17452" } ], "pmid": "" } ], "molecular_function": [ { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "O17452", "url": "https://www.uniprot.org/uniprotkb/O17452" } ], "pmid": "" }, { "name": "structural constituent of chitin-based cuticle", "id": "GO:0005214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005214", "evidence": [ { "database": "UniProtKB", "id": "O17452", "url": "https://www.uniprot.org/uniprotkb/O17452" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "O17452-1" }, { "uniprot_canonical_ac": "O62526-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "O62526", "url": "https://www.uniprot.org/uniprotkb/O62526" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 307, "chemical_mass": 33744.0, "gene_names": "Ant2;ANT2;Ant2;CG1683;Dmel\\CG1683;Dmel_CG1683;FBgn0025111;l(1)G0126;l(1)G0247;l(1)G0386", "protein_name": "ADP/ATP translocase", "disease": [ { "disease_id": "DOID:0080130", "name": "mitochondrial DNA depletion syndrome 12a", "description": "A mitochondrial DNA depletion syndrome that is characterized by severe hypotonia due to mitochondrial dysfunction apparent at birth and has_material_basis_in autosomal dominant inheritance of heterozygous mutation in the solute carrier family 25 member 4 gene on chromosome 4q35.", "url": "https://disease-ontology.org/term/DOID:0080130", "evidence": [ { "id": "0080130", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080130" } ], "weight": 0.0 }, { "disease_id": "DOID:0080335", "name": "mitochondrial DNA depletion syndrome 12b", "description": "A mitochondrial DNA depletion syndrome that is characterized by childhood onset of slowly progressive hypertrophic cardiomyopathy and generalized skeletal myopathy resulting in exercise intolerance, muscle weakness, and atrophy, and has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the the solute carrier family 25 member 4 on chromosome 4q35.", "url": "https://disease-ontology.org/term/DOID:0080335", "evidence": [ { "id": "0080335", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080335" } ], "weight": 0.0 }, { "disease_id": "DOID:0110429", "name": "dilated cardiomyopathy 1H", "description": "A dilated cardiomyopathy that has_material_basis_in variation in the chromosome region 2q14-q22.", "url": "https://disease-ontology.org/term/DOID:0110429", "evidence": [ { "id": "0110429", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110429" } ], "weight": 0.0 }, { "disease_id": "DOID:0111517", "name": "autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 2", "description": "A chronic progressive external ophthalmoplegia that has_material_basis_in heterozygous mutation in the SLC25A4 gene on chromosome 4q35.1.", "url": "https://disease-ontology.org/term/DOID:0111517", "evidence": [ { "id": "0111517", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111517" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:11727", "name": "facioscapulohumeral muscular dystrophy", "description": "", "url": "https://disease-ontology.org/term/DOID:11727", "evidence": [ { "id": "11727", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11727" } ], "weight": 0.0 }, { "disease_id": "DOID:11984", "name": "hypertrophic cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause.", "url": "https://disease-ontology.org/term/DOID:11984", "evidence": [ { "id": "11984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11984" } ], "weight": 0.0 }, { "disease_id": "DOID:12558", "name": "chronic progressive external ophthalmoplegia", "description": "A mitochondrial myopathy characterized by weakness of extraocular muscles, usually evident from bilateral ptosis and/or ophthalmoplegia, that has_material_basis_in mitochondrial DNA deletions.", "url": "https://disease-ontology.org/term/DOID:12558", "evidence": [ { "id": "12558", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12558" } ], "weight": 0.0 }, { "disease_id": "DOID:12935", "name": "alcoholic cardiomyopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:12935", "evidence": [ { "id": "12935", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12935" } ], "weight": 0.0 }, { "disease_id": "DOID:699", "name": "mitochondrial myopathy", "description": "A myopathy that is characterized by mitochondrial dysfunction.", "url": "https://disease-ontology.org/term/DOID:699", "evidence": [ { "id": "699", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:699" } ], "weight": 0.0 }, { "disease_id": "DOID:700", "name": "mitochondrial metabolism disease", "description": "An inherited metabolic disorder that involves mitochondrial metabolism dysfunction.", "url": "https://disease-ontology.org/term/DOID:700", "evidence": [ { "id": "700", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:700" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "O62526", "url": "https://www.uniprot.org/uniprotkb/O62526" } ], "pmid": "" }, { "name": "mitochondrial permeability transition pore complex", "id": "GO:0005757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005757", "evidence": [ { "database": "UniProtKB", "id": "O62526", "url": "https://www.uniprot.org/uniprotkb/O62526" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial transport", "id": "GO:0006839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006839", "evidence": [ { "database": "UniProtKB", "id": "O62526", "url": "https://www.uniprot.org/uniprotkb/O62526" } ], "pmid": "" }, { "name": "regulation of mitochondrial membrane permeability", "id": "GO:0046902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046902", "evidence": [ { "database": "UniProtKB", "id": "O62526", "url": "https://www.uniprot.org/uniprotkb/O62526" } ], "pmid": "" }, { "name": "mitochondrial ADP transmembrane transport", "id": "GO:0140021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140021", "evidence": [ { "database": "UniProtKB", "id": "O62526", "url": "https://www.uniprot.org/uniprotkb/O62526" } ], "pmid": "" }, { "name": "mitochondrial ATP transmembrane transport", "id": "GO:1990544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990544", "evidence": [ { "database": "UniProtKB", "id": "O62526", "url": "https://www.uniprot.org/uniprotkb/O62526" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP:ADP antiporter activity", "id": "GO:0005471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005471", "evidence": [ { "database": "UniProtKB", "id": "O62526", "url": "https://www.uniprot.org/uniprotkb/O62526" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "O62526-1" }, { "uniprot_canonical_ac": "O76861-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "O76861", "url": "https://www.uniprot.org/uniprotkb/O76861" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 552, "chemical_mass": 60969.0, "gene_names": "EG:100G10.1;CG2685;Dmel\\CG2685;Dmel_CG2685;EG:100G10.1", "protein_name": "Wbp11/ELF5/Saf1 N-terminal domain-containing protein", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "O76861", "url": "https://www.uniprot.org/uniprotkb/O76861" } ], "pmid": "" }, { "name": "protein phosphatase regulator activity", "id": "GO:0019888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019888", "evidence": [ { "database": "UniProtKB", "id": "O76861", "url": "https://www.uniprot.org/uniprotkb/O76861" } ], "pmid": "" } ], "biological_process": [ { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "O76861", "url": "https://www.uniprot.org/uniprotkb/O76861" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "O76861", "url": "https://www.uniprot.org/uniprotkb/O76861" } ], "pmid": "" } ], "cellular_component": [ { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "O76861", "url": "https://www.uniprot.org/uniprotkb/O76861" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "O76861", "url": "https://www.uniprot.org/uniprotkb/O76861" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "O76861-1", "start_pos": "361", "end_pos": "361", "site_lbl": "Thr361", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 361, "start_aa": "Thr", "end_pos": 361, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr361", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "O76861-1", "start_pos": "368", "end_pos": "368", "site_lbl": "Thr368", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 368, "start_aa": "Thr", "end_pos": 368, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr368", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "O76861-1" }, { "uniprot_canonical_ac": "O96660-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 486, "chemical_mass": 53677.0, "gene_names": "Smox;3;CG2262;DSMAD2;DSmad2;Dmel\\CG2262;SMAD2;SMOX;Sad;Smad2/3;Smad2;Smad;SmoX;Smox;dSMAD2;dSmad2;dSmad;dsmad2;l(1)G0348;sad;smad2;smox;ted;tmp", "protein_name": "SMAD family member 2", "disease": [ { "disease_id": "DOID:0050156", "name": "idiopathic pulmonary fibrosis", "description": "A pulmonary fibrosis that is characterized by scarring of the lung characterized by stiffness in the lungs and makes it difficult to breathe.", "url": "https://disease-ontology.org/term/DOID:0050156", "evidence": [ { "id": "0050156", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050156" } ], "weight": 0.0 }, { "disease_id": "DOID:0060071", "name": "pre-malignant neoplasm", "description": "A disease of cellular proliferation that results in abnormal growths in the body, which do not invade or destroy the surrounding tissue but, given enough time, will transform into a cancer.", "url": "https://disease-ontology.org/term/DOID:0060071", "evidence": [ { "id": "0060071", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060071" } ], "weight": 0.0 }, { "disease_id": "DOID:0060964", "name": "Loeys-Dietz syndrome 6", "description": "A Loeys-Dietz syndrome characterized by aortic/arterial aneurysm and dissection in association with connective tissue findings that has_material_basis_in heterozygous mutation in the SMAD2 gene (601366) on chromosome 18q21.", "url": "https://disease-ontology.org/term/DOID:0060964", "evidence": [ { "id": "0060964", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060964" } ], "weight": 0.0 }, { "disease_id": "DOID:0070237", "name": "Loeys-Dietz syndrome 3", "description": "A Loeys-Dietz syndrome that has_material_basis_in heterozygous mutation in the SMAD3 gene on chromosome 15q.", "url": "https://disease-ontology.org/term/DOID:0070237", "evidence": [ { "id": "0070237", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070237" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10892", "name": "hypospadias", "description": "A physical disorder characterized by an abnormally placed urethral opening on the underside of the penis or on the perineum.", "url": "https://disease-ontology.org/term/DOID:10892", "evidence": [ { "id": "10892", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10892" } ], "weight": 0.0 }, { "disease_id": "DOID:12935", "name": "alcoholic cardiomyopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:12935", "evidence": [ { "id": "12935", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12935" } ], "weight": 0.0 }, { "disease_id": "DOID:1380", "name": "endometrial cancer", "description": "A uterine cancer that is located_in tissues lining the uterus.", "url": "https://disease-ontology.org/term/DOID:1380", "evidence": [ { "id": "1380", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1380" } ], "weight": 0.0 }, { "disease_id": "DOID:14018", "name": "alcoholic liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:14018", "evidence": [ { "id": "14018", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14018" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:2394", "name": "ovarian cancer", "description": "A female reproductive organ cancer that is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:2394", "evidence": [ { "id": "2394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2394" } ], "weight": 0.0 }, { "disease_id": "DOID:3459", "name": "breast carcinoma", "description": "A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:3459", "evidence": [ { "id": "3459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3459" } ], "weight": 0.0 }, { "disease_id": "DOID:3498", "name": "pancreatic ductal adenocarcinoma", "description": "A pancreatic adenocarcinoma that derives_from pancreatic duct cells.", "url": "https://disease-ontology.org/term/DOID:3498", "evidence": [ { "id": "3498", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3498" } ], "weight": 0.0 }, { "disease_id": "DOID:3744", "name": "cervical squamous cell carcinoma", "description": "A cervix carcinoma that has_material_basis_in squamous cells of the cervix.", "url": "https://disease-ontology.org/term/DOID:3744", "evidence": [ { "id": "3744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3744" } ], "weight": 0.0 }, { "disease_id": "DOID:3883", "name": "Lynch syndrome", "description": "A syndrome that is characterized by an increased risk for colon cancer and cancers of the endometrium, ovary, stomach, small intestine, hepatobiliary tract, urinary tract, brain, and skin and has_material_basis_in mutation of mismatch repair genes that increases the risk of many types of cancers.", "url": "https://disease-ontology.org/term/DOID:3883", "evidence": [ { "id": "3883", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3883" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:4001", "name": "ovarian carcinoma", "description": "An ovarian cancer that has_material_basis_in epithelial tissue and is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:4001", "evidence": [ { "id": "4001", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4001" } ], "weight": 0.0 }, { "disease_id": "DOID:4362", "name": "cervical cancer", "description": "A female reproductive organ cancer that is located_in the cervix.", "url": "https://disease-ontology.org/term/DOID:4362", "evidence": [ { "id": "4362", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4362" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:8398", "name": "osteoarthritis", "description": "An arthritis that has_material_basis_in worn out cartilage located_in joint.", "url": "https://disease-ontology.org/term/DOID:8398", "evidence": [ { "id": "8398", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8398" } ], "weight": 0.0 }, { "disease_id": "DOID:9975", "name": "cocaine dependence", "description": "A drug dependence that is a psychological dependency on the regular use of cocaine.", "url": "https://disease-ontology.org/term/DOID:9975", "evidence": [ { "id": "9975", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9975" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of glycogen catabolic process", "id": "GO:0045819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045819", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "regulation of synapse structure or activity", "id": "GO:0050803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050803", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "cellular response to glucose stimulus", "id": "GO:0071333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071333", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "glucose homeostasis", "id": "GO:0042593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042593", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "negative regulation of autophagy", "id": "GO:0010507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010507", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "SMAD protein signal transduction", "id": "GO:0060395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060395", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "activin receptor signaling pathway", "id": "GO:0032924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032924", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "dendrite morphogenesis", "id": "GO:0048813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048813", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "neuron development", "id": "GO:0048666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048666", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "positive regulation of neuroblast proliferation", "id": "GO:0002052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002052", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "determination of adult lifespan", "id": "GO:0008340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008340", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis", "id": "GO:0090256", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090256", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "imaginal disc growth", "id": "GO:0007446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007446", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "imaginal disc-derived wing morphogenesis", "id": "GO:0007476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007476", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "mushroom body development", "id": "GO:0016319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016319", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "regulation of imaginal disc-derived wing size", "id": "GO:0044719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044719", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "R8 cell fate specification", "id": "GO:0045464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045464", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "positive regulation of imaginal disc growth", "id": "GO:0045572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045572", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" } ], "molecular_function": [ { "name": "co-SMAD binding", "id": "GO:0070410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070410", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "I-SMAD binding", "id": "GO:0070411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070411", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" } ], "cellular_component": [ { "name": "heteromeric SMAD protein complex", "id": "GO:0071144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071144", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "O96660-1", "start_pos": "196", "end_pos": "196", "site_lbl": "Thr196", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 196, "start_aa": "Thr", "end_pos": 196, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr196", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "O96660-1", "start_pos": "484", "end_pos": "484", "site_lbl": "Ser484", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" }, { "database": "PubMed", "id": "9887103", "url": "https://glygen.org/publication/PubMed/9887103" } ] } ] }, { "uniprot_canonical_ac": "O96660-1", "start_pos": "486", "end_pos": "486", "site_lbl": "Ser486", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" }, { "database": "PubMed", "id": "9887103", "url": "https://glygen.org/publication/PubMed/9887103" } ] } ] }, { "uniprot_canonical_ac": "O96660-1", "start_pos": "300", "end_pos": "300", "site_lbl": "Glu300", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "K", "comment": "Reduces phosphorylation by babo and reduces the inhibitory effect on phosphorylation of R-SMADMad by babo.", "evidence": [ { "database": "UniProtKB", "id": "O96660", "url": "https://www.uniprot.org/uniprotkb/O96660" }, { "database": "PubMed", "id": "22563507", "url": "https://glygen.org/publication/PubMed/22563507" } ] } ] } ], "record_id": "O96660-1" }, { "uniprot_canonical_ac": "P83262-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "P83262", "url": "https://www.uniprot.org/uniprotkb/P83262" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 78, "chemical_mass": 8871.0, "gene_names": "BobA;Bob-A;BobA;Bob;CG12487;Dmel\\CG12487;Dmel_CG12487;bobA", "protein_name": "", "disease": [], "biological_process": [ { "name": "cell fate specification", "id": "GO:0001708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001708", "evidence": [ { "database": "UniProtKB", "id": "P83262", "url": "https://www.uniprot.org/uniprotkb/P83262" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "P83262", "url": "https://www.uniprot.org/uniprotkb/P83262" } ], "pmid": "" }, { "name": "negative regulation of Notch signaling pathway", "id": "GO:0045746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045746", "evidence": [ { "database": "UniProtKB", "id": "P83262", "url": "https://www.uniprot.org/uniprotkb/P83262" } ], "pmid": "" }, { "name": "sensory organ precursor cell fate determination", "id": "GO:0016360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016360", "evidence": [ { "database": "UniProtKB", "id": "P83262", "url": "https://www.uniprot.org/uniprotkb/P83262" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "P83262", "url": "https://www.uniprot.org/uniprotkb/P83262" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P83262-1" }, { "uniprot_canonical_ac": "P83263-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "P83263", "url": "https://www.uniprot.org/uniprotkb/P83263" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 78, "chemical_mass": 8841.0, "gene_names": "Dmel\\CG13465;CG13465;Dmel\\CG13465;Dmel_CG13465", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "P83263-1" }, { "uniprot_canonical_ac": "Q0E8P5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0E8P5", "url": "https://www.uniprot.org/uniprotkb/Q0E8P5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 625, "chemical_mass": 70527.0, "gene_names": "Dmel\\CG5758;CG5758;Dmel\\CG5758;Dmel_CG5758", "protein_name": "FAS1 domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q0E8P5", "url": "https://www.uniprot.org/uniprotkb/Q0E8P5" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "Q0E8P5", "url": "https://www.uniprot.org/uniprotkb/Q0E8P5" } ], "pmid": "" } ], "biological_process": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "Q0E8P5", "url": "https://www.uniprot.org/uniprotkb/Q0E8P5" } ], "pmid": "" }, { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "Q0E8P5", "url": "https://www.uniprot.org/uniprotkb/Q0E8P5" } ], "pmid": "" }, { "name": "synaptic target recognition", "id": "GO:0008039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008039", "evidence": [ { "database": "UniProtKB", "id": "Q0E8P5", "url": "https://www.uniprot.org/uniprotkb/Q0E8P5" } ], "pmid": "" } ], "molecular_function": [ { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "Q0E8P5", "url": "https://www.uniprot.org/uniprotkb/Q0E8P5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q0E8P5-1" }, { "uniprot_canonical_ac": "Q0E8Q6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0E8Q6", "url": "https://www.uniprot.org/uniprotkb/Q0E8Q6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 661, "chemical_mass": 75456.0, "gene_names": "DS00797.6;BG:DS00797.6;CG16863;DS00797.6;Dmel\\CG16863;Dmel_CG16863", "protein_name": "BED-type domain-containing protein", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q0E8Q6", "url": "https://www.uniprot.org/uniprotkb/Q0E8Q6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q0E8Q6", "url": "https://www.uniprot.org/uniprotkb/Q0E8Q6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q0E8Q6", "url": "https://www.uniprot.org/uniprotkb/Q0E8Q6" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q0E8Q6", "url": "https://www.uniprot.org/uniprotkb/Q0E8Q6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q0E8Q6-1" }, { "uniprot_canonical_ac": "Q0E9N0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0E9N0", "url": "https://www.uniprot.org/uniprotkb/Q0E9N0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 807, "chemical_mass": 87623.0, "gene_names": "Dmel\\CG15236;CG15236;Dmel\\CG15236;Dmel_CG15236", "protein_name": "", "disease": [], "molecular_function": [ { "name": "mRNA regulatory element binding translation repressor activity", "id": "GO:0000900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000900", "evidence": [ { "database": "UniProtKB", "id": "Q0E9N0", "url": "https://www.uniprot.org/uniprotkb/Q0E9N0" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q0E9N0", "url": "https://www.uniprot.org/uniprotkb/Q0E9N0" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of translational initiation", "id": "GO:0045947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045947", "evidence": [ { "database": "UniProtKB", "id": "Q0E9N0", "url": "https://www.uniprot.org/uniprotkb/Q0E9N0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q0E9N0-1", "start_pos": "341", "end_pos": "341", "site_lbl": "Thr341", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 341, "start_aa": "Thr", "end_pos": 341, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr341", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q0E9N0-1", "start_pos": "487", "end_pos": "487", "site_lbl": "Thr487", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 487, "start_aa": "Thr", "end_pos": 487, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr487", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q0E9N0-1" }, { "uniprot_canonical_ac": "Q0KHY8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0KHY8", "url": "https://www.uniprot.org/uniprotkb/Q0KHY8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 423, "chemical_mass": 47144.0, "gene_names": "VhaAC45RP;BcDNA:RH09162;CG2176;CG31030;Dmel\\CG31030;Dmel_CG31030;VhaAC45RP;anon-EST:Posey81", "protein_name": "", "disease": [], "cellular_component": [ { "name": "proton-transporting V-type ATPase complex", "id": "GO:0033176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033176", "evidence": [ { "database": "UniProtKB", "id": "Q0KHY8", "url": "https://www.uniprot.org/uniprotkb/Q0KHY8" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "Q0KHY8", "url": "https://www.uniprot.org/uniprotkb/Q0KHY8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q0KHY8", "url": "https://www.uniprot.org/uniprotkb/Q0KHY8" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of cellular pH", "id": "GO:0030641", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030641", "evidence": [ { "database": "UniProtKB", "id": "Q0KHY8", "url": "https://www.uniprot.org/uniprotkb/Q0KHY8" } ], "pmid": "" }, { "name": "synaptic vesicle lumen acidification", "id": "GO:0097401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097401", "evidence": [ { "database": "UniProtKB", "id": "Q0KHY8", "url": "https://www.uniprot.org/uniprotkb/Q0KHY8" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATPase regulator activity", "id": "GO:0060590", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060590", "evidence": [ { "database": "UniProtKB", "id": "Q0KHY8", "url": "https://www.uniprot.org/uniprotkb/Q0KHY8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q0KHY8-1" }, { "uniprot_canonical_ac": "Q9VDI5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDI5", "url": "https://www.uniprot.org/uniprotkb/Q9VDI5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 281, "chemical_mass": 32536.0, "gene_names": "Dm_3R:88623;Dmel\\CG17271;CG17271;Dm_3R:88623;Dmel\\CG17271;Dmel_CG17271", "protein_name": "EF-hand domain-containing protein", "disease": [ { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VDI5", "url": "https://www.uniprot.org/uniprotkb/Q9VDI5" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q9VDI5", "url": "https://www.uniprot.org/uniprotkb/Q9VDI5" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q9VDI5", "url": "https://www.uniprot.org/uniprotkb/Q9VDI5" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q9VDI5", "url": "https://www.uniprot.org/uniprotkb/Q9VDI5" } ], "pmid": "" } ], "biological_process": [ { "name": "mating", "id": "GO:0007618", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007618", "evidence": [ { "database": "UniProtKB", "id": "Q9VDI5", "url": "https://www.uniprot.org/uniprotkb/Q9VDI5" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q9VDI5", "url": "https://www.uniprot.org/uniprotkb/Q9VDI5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VDI5-1" }, { "uniprot_canonical_ac": "Q0KIE7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0KIE7", "url": "https://www.uniprot.org/uniprotkb/Q0KIE7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1549, "chemical_mass": 170168.0, "gene_names": "Ank;ANK;Ank;CG1651;CG32008;DAnk1;Dank1;Dmel\\CG1651;Dmel_CG1651;ank;dank1", "protein_name": "", "disease": [ { "disease_id": "DOID:0050668", "name": "alcohol-related birth defects", "description": "A fetal alcohol spectrum disorder that results in damage to organs, bones, or muscles due to prenatal alcohol exposure.", "url": "https://disease-ontology.org/term/DOID:0050668", "evidence": [ { "id": "0050668", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050668" } ], "weight": 0.0 }, { "disease_id": "DOID:0050824", "name": "sinoatrial node disease", "description": "A heart conduction disease that is characterized by dysfunction of the impulse-generating (pacemaker) tissue located in the right atrium of the heart which generates normal sinus rhythm.", "url": "https://disease-ontology.org/term/DOID:0050824", "evidence": [ { "id": "0050824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050824" } ], "weight": 0.0 }, { "disease_id": "DOID:0060224", "name": "atrial fibrillation", "description": "A heart conduction disease that is characterized by uncoordinated electrical activity in the heart's upper chambers (the atria), which causes the heartbeat to become fast and irregular and has symptoms palpitations, weakness, fatigue, lightheadedness, dizziness, confusion, shortness of breath and chest pain.", "url": "https://disease-ontology.org/term/DOID:0060224", "evidence": [ { "id": "0060224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060224" } ], "weight": 0.0 }, { "disease_id": "DOID:0081202", "name": "autosomal recessive intellectual developmental disorder 37", "description": "An autosomal recessive intellectual developmental disorder that has_material_basis_in homozygous mutation in the ANK3 gene on chromosome 10q21.", "url": "https://disease-ontology.org/term/DOID:0081202", "evidence": [ { "id": "0081202", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081202" } ], "weight": 0.0 }, { "disease_id": "DOID:0110916", "name": "hereditary spherocytosis type 1", "description": "A hereditary spherocytosis that has_material_basis_in an autosomal dominant mutation of the ANK1 gene on chromosome 8p11.21.", "url": "https://disease-ontology.org/term/DOID:0110916", "evidence": [ { "id": "0110916", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110916" } ], "weight": 0.0 }, { "disease_id": "DOID:0111700", "name": "ankyrin-B-related cardiac arrhythmia", "description": "A heart disease characterized by a broad spectrum of cardiac arrhythmias including; bradycardia, sinus arrhythmia, delayed conduction/conduction block, idiopathic ventricular fibrillation, and catecholaminergic polymorphic ventricular tachycardia that has_material_basis_in heterozygous mutation in the ANK2 gene on chromosome 4q25-q26.", "url": "https://disease-ontology.org/term/DOID:0111700", "evidence": [ { "id": "0111700", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111700" } ], "weight": 0.0 }, { "disease_id": "DOID:12365", "name": "malaria", "description": "A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle.", "url": "https://disease-ontology.org/term/DOID:12365", "evidence": [ { "id": "12365", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12365" } ], "weight": 0.0 }, { "disease_id": "DOID:12849", "name": "autistic disorder", "description": "An autism spectrum disorder that is characterized by symptoms across all three symptom domains (communication, social, restricted repetitive interests and behaviors), delayed language development, and symptom onset prior to age 3 years.", "url": "https://disease-ontology.org/term/DOID:12849", "evidence": [ { "id": "12849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12849" } ], "weight": 0.0 }, { "disease_id": "DOID:12971", "name": "hereditary spherocytosis", "description": "A congenital hemolytic anemia characterized by the production of red blood cells with a sphere shape, rather than the normal biconcave disk shape.", "url": "https://disease-ontology.org/term/DOID:12971", "evidence": [ { "id": "12971", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12971" } ], "weight": 0.0 }, { "disease_id": "DOID:13884", "name": "sick sinus syndrome", "description": "", "url": "https://disease-ontology.org/term/DOID:13884", "evidence": [ { "id": "13884", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13884" } ], "weight": 0.0 }, { "disease_id": "DOID:1824", "name": "status epilepticus", "description": "", "url": "https://disease-ontology.org/term/DOID:1824", "evidence": [ { "id": "1824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1824" } ], "weight": 0.0 }, { "disease_id": "DOID:2055", "name": "post-traumatic stress disorder", "description": "An anxiety disorder which results from a traumatic experience that results in psychological trauma.", "url": "https://disease-ontology.org/term/DOID:2055", "evidence": [ { "id": "2055", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2055" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:2355", "name": "anemia", "description": "A hematopoietic system disease that is characterized by a decrease in the normal number of red blood cells.", "url": "https://disease-ontology.org/term/DOID:2355", "evidence": [ { "id": "2355", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2355" } ], "weight": 0.0 }, { "disease_id": "DOID:2843", "name": "long QT syndrome", "description": "An autosomal genetic disease that is characterized by delayed repolarization of the heart following a heartbeat increases the risk of episodes of torsade de pointes (TDP, a form of irregular heartbeat that originates from the ventricles).", "url": "https://disease-ontology.org/term/DOID:2843", "evidence": [ { "id": "2843", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2843" } ], "weight": 0.0 }, { "disease_id": "DOID:3312", "name": "bipolar disorder", "description": "A mood disorder that involves alternating periods of mania and depression.", "url": "https://disease-ontology.org/term/DOID:3312", "evidence": [ { "id": "3312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3312" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "Q0KIE7", "url": "https://www.uniprot.org/uniprotkb/Q0KIE7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q0KIE7", "url": "https://www.uniprot.org/uniprotkb/Q0KIE7" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "Q0KIE7", "url": "https://www.uniprot.org/uniprotkb/Q0KIE7" } ], "pmid": "" }, { "name": "spectrosome", "id": "GO:0045170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045170", "evidence": [ { "database": "UniProtKB", "id": "Q0KIE7", "url": "https://www.uniprot.org/uniprotkb/Q0KIE7" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q0KIE7", "url": "https://www.uniprot.org/uniprotkb/Q0KIE7" } ], "pmid": "" }, { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "Q0KIE7", "url": "https://www.uniprot.org/uniprotkb/Q0KIE7" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "Q0KIE7", "url": "https://www.uniprot.org/uniprotkb/Q0KIE7" } ], "pmid": "" }, { "name": "spectrin binding", "id": "GO:0030507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030507", "evidence": [ { "database": "UniProtKB", "id": "Q0KIE7", "url": "https://www.uniprot.org/uniprotkb/Q0KIE7" } ], "pmid": "" }, { "name": "cytoskeletal anchor activity", "id": "GO:0008093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008093", "evidence": [ { "database": "UniProtKB", "id": "Q0KIE7", "url": "https://www.uniprot.org/uniprotkb/Q0KIE7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q0KIE7-1", "start_pos": "1538", "end_pos": "1538", "site_lbl": "Thr1538", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1538, "start_aa": "Thr", "end_pos": 1538, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1538", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q0KIE7-1" }, { "uniprot_canonical_ac": "Q2MGM0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q2MGM0", "url": "https://www.uniprot.org/uniprotkb/Q2MGM0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 606, "chemical_mass": 70985.0, "gene_names": "Ir62a;62a;CG12090;CG33971;DmelIR62a;Dmel\\CG33971;Dmel_CG33971;IR62a;Ir62a", "protein_name": "", "disease": [], "biological_process": [ { "name": "detection of chemical stimulus", "id": "GO:0009593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009593", "evidence": [ { "database": "UniProtKB", "id": "Q2MGM0", "url": "https://www.uniprot.org/uniprotkb/Q2MGM0" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q2MGM0", "url": "https://www.uniprot.org/uniprotkb/Q2MGM0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q2MGM0", "url": "https://www.uniprot.org/uniprotkb/Q2MGM0" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "Q2MGM0", "url": "https://www.uniprot.org/uniprotkb/Q2MGM0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q2MGM0-1" }, { "uniprot_canonical_ac": "Q2PDQ0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q2PDQ0", "url": "https://www.uniprot.org/uniprotkb/Q2PDQ0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1519, "chemical_mass": 174057.0, "gene_names": "Dmel\\CG34027;BP1028;CG34027;Dmel\\CG34027;Dmel_CG34027", "protein_name": "Generative cell specific-1/HAP2 domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q2PDQ0-1" }, { "uniprot_canonical_ac": "Q2PDQ7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q2PDQ7", "url": "https://www.uniprot.org/uniprotkb/Q2PDQ7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 151, "chemical_mass": 17100.0, "gene_names": "CG34053;BP1087;CG34053;CG42823;Dmel\\CG42823;Dmel_CG42823;HDC14119", "protein_name": "Kazal-like domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q2PDQ7", "url": "https://www.uniprot.org/uniprotkb/Q2PDQ7" } ], "pmid": "" } ], "biological_process": [ { "name": "mating", "id": "GO:0007618", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007618", "evidence": [ { "database": "UniProtKB", "id": "Q2PDQ7", "url": "https://www.uniprot.org/uniprotkb/Q2PDQ7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q2PDQ7-1" }, { "uniprot_canonical_ac": "Q2PDZ4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q2PDZ4", "url": "https://www.uniprot.org/uniprotkb/Q2PDZ4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 350, "chemical_mass": 38305.0, "gene_names": "MIP08535;BP1025;CG34002;Dmel\\CG34002;Dmel_CG34002;MIP08535", "protein_name": "SCP domain-containing protein", "disease": [], "biological_process": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "Q2PDZ4", "url": "https://www.uniprot.org/uniprotkb/Q2PDZ4" } ], "pmid": "" }, { "name": "mating", "id": "GO:0007618", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007618", "evidence": [ { "database": "UniProtKB", "id": "Q2PDZ4", "url": "https://www.uniprot.org/uniprotkb/Q2PDZ4" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q2PDZ4", "url": "https://www.uniprot.org/uniprotkb/Q2PDZ4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q2PDZ4-1" }, { "uniprot_canonical_ac": "Q4AB35-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q4AB35", "url": "https://www.uniprot.org/uniprotkb/Q4AB35" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 183, "chemical_mass": 21225.0, "gene_names": "HDC12790;CG33784;Dmel\\CG33784;Dmel_CG33784;HDC12790", "protein_name": "MD-2-related lipid-recognition domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q4AB35-1" }, { "uniprot_canonical_ac": "Q4AB39-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q4AB39", "url": "https://www.uniprot.org/uniprotkb/Q4AB39" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 168, "chemical_mass": 20089.0, "gene_names": "Dmel\\CG33654;CG33654;Dmel\\CG33654;Dmel_CG33654", "protein_name": "MD-2-related lipid-recognition domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q4AB39-1" }, { "uniprot_canonical_ac": "Q4ABH2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q4ABH2", "url": "https://www.uniprot.org/uniprotkb/Q4ABH2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 182, "chemical_mass": 20909.0, "gene_names": "Dmel\\CG33927;CG33927;Dmel\\CG33927;Dmel_CG33927", "protein_name": "MD-2-related lipid-recognition domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q4ABH2-1" }, { "uniprot_canonical_ac": "Q4ABI1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q4ABI1", "url": "https://www.uniprot.org/uniprotkb/Q4ABI1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 165, "chemical_mass": 19478.0, "gene_names": "Dmel\\CG33912;CG33912;Dmel\\CG33912;Dmel_CG33912", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q4ABI1-1" }, { "uniprot_canonical_ac": "Q4ABJ2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q4ABJ2", "url": "https://www.uniprot.org/uniprotkb/Q4ABJ2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 175, "chemical_mass": 20760.0, "gene_names": "Dmel\\CG33688;CG33688;Dmel\\CG33688;Dmel_CG33688", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q4ABJ2-1" }, { "uniprot_canonical_ac": "Q4ABJ9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q4ABJ9", "url": "https://www.uniprot.org/uniprotkb/Q4ABJ9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 162, "chemical_mass": 18143.0, "gene_names": "bs03f11.y1;CG33710;Dmel\\CG33710;Dmel_CG33710;NEST:bs03f11;bs03f11.y1", "protein_name": "Seminal fluid protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q4ABJ9-1" }, { "uniprot_canonical_ac": "Q8IPM6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IPM6", "url": "https://www.uniprot.org/uniprotkb/Q8IPM6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 736, "chemical_mass": 80558.0, "gene_names": "Dmel\\CG9795;CG9795;Dmel\\CG9795;Dmel_CG9795", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IPM6-1" }, { "uniprot_canonical_ac": "Q59E38-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q59E38", "url": "https://www.uniprot.org/uniprotkb/Q59E38" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 401, "chemical_mass": 45627.0, "gene_names": "upd3;CG15062/CG5963;CG15062;CG33542;CG5963;Dmel\\CG33542;Dmel_CG33542;UPD3;Unpaireds;Upd-3;Upd-like;Upd3;Upd;cg15062;cg5963;odsy;od;os;sy;upd 3;upd-3;upd3;upd", "protein_name": "", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q59E38", "url": "https://www.uniprot.org/uniprotkb/Q59E38" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q59E38", "url": "https://www.uniprot.org/uniprotkb/Q59E38" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "Q59E38", "url": "https://www.uniprot.org/uniprotkb/Q59E38" } ], "pmid": "" }, { "name": "antimicrobial humoral response", "id": "GO:0019730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019730", "evidence": [ { "database": "UniProtKB", "id": "Q59E38", "url": "https://www.uniprot.org/uniprotkb/Q59E38" } ], "pmid": "" }, { "name": "wound healing", "id": "GO:0042060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042060", "evidence": [ { "database": "UniProtKB", "id": "Q59E38", "url": "https://www.uniprot.org/uniprotkb/Q59E38" } ], "pmid": "" }, { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "Q59E38", "url": "https://www.uniprot.org/uniprotkb/Q59E38" } ], "pmid": "" }, { "name": "paracrine signaling", "id": "GO:0038001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038001", "evidence": [ { "database": "UniProtKB", "id": "Q59E38", "url": "https://www.uniprot.org/uniprotkb/Q59E38" } ], "pmid": "" }, { "name": "intestinal epithelial structure maintenance", "id": "GO:0060729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060729", "evidence": [ { "database": "UniProtKB", "id": "Q59E38", "url": "https://www.uniprot.org/uniprotkb/Q59E38" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway via JAK-STAT", "id": "GO:0007259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007259", "evidence": [ { "database": "UniProtKB", "id": "Q59E38", "url": "https://www.uniprot.org/uniprotkb/Q59E38" } ], "pmid": "" }, { "name": "intestinal stem cell homeostasis", "id": "GO:0036335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036335", "evidence": [ { "database": "UniProtKB", "id": "Q59E38", "url": "https://www.uniprot.org/uniprotkb/Q59E38" } ], "pmid": "" }, { "name": "embryonic development via the syncytial blastoderm", "id": "GO:0001700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001700", "evidence": [ { "database": "UniProtKB", "id": "Q59E38", "url": "https://www.uniprot.org/uniprotkb/Q59E38" } ], "pmid": "" }, { "name": "lamellocyte differentiation", "id": "GO:0035171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035171", "evidence": [ { "database": "UniProtKB", "id": "Q59E38", "url": "https://www.uniprot.org/uniprotkb/Q59E38" } ], "pmid": "" } ], "molecular_function": [ { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "Q59E38", "url": "https://www.uniprot.org/uniprotkb/Q59E38" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q59E38-1" }, { "uniprot_canonical_ac": "Q59E67-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q59E67", "url": "https://www.uniprot.org/uniprotkb/Q59E67" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 150, "chemical_mass": 16509.0, "gene_names": "soul;CG12648;CG33557;Dmel\\CG33557;Dmel_CG33557", "protein_name": "BHLH domain-containing protein", "disease": [], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "Q59E67", "url": "https://www.uniprot.org/uniprotkb/Q59E67" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "Q59E67", "url": "https://www.uniprot.org/uniprotkb/Q59E67" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "Q59E67", "url": "https://www.uniprot.org/uniprotkb/Q59E67" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q59E67", "url": "https://www.uniprot.org/uniprotkb/Q59E67" } ], "pmid": "" }, { "name": "E-box binding", "id": "GO:0070888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070888", "evidence": [ { "database": "UniProtKB", "id": "Q59E67", "url": "https://www.uniprot.org/uniprotkb/Q59E67" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q59E67", "url": "https://www.uniprot.org/uniprotkb/Q59E67" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q59E67", "url": "https://www.uniprot.org/uniprotkb/Q59E67" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q59E67", "url": "https://www.uniprot.org/uniprotkb/Q59E67" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q59E67", "url": "https://www.uniprot.org/uniprotkb/Q59E67" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q59E67", "url": "https://www.uniprot.org/uniprotkb/Q59E67" } ], "pmid": "" }, { "name": "developmental process", "id": "GO:0032502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032502", "evidence": [ { "database": "UniProtKB", "id": "Q59E67", "url": "https://www.uniprot.org/uniprotkb/Q59E67" } ], "pmid": "" }, { "name": "pupation", "id": "GO:0035074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035074", "evidence": [ { "database": "UniProtKB", "id": "Q59E67", "url": "https://www.uniprot.org/uniprotkb/Q59E67" } ], "pmid": "" }, { "name": "molting cycle, chitin-based cuticle", "id": "GO:0007591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007591", "evidence": [ { "database": "UniProtKB", "id": "Q59E67", "url": "https://www.uniprot.org/uniprotkb/Q59E67" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q59E67-1" }, { "uniprot_canonical_ac": "Q6IGA4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q6IGA4", "url": "https://www.uniprot.org/uniprotkb/Q6IGA4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 124, "chemical_mass": 13596.0, "gene_names": "Acp53C14c;Acp53C14c;CG33530;Dmel\\CG33530;Dmel_CG33530;HDC06801", "protein_name": "", "disease": [], "biological_process": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "Q6IGA4", "url": "https://www.uniprot.org/uniprotkb/Q6IGA4" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q6IGA4", "url": "https://www.uniprot.org/uniprotkb/Q6IGA4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q6IGA4-1" }, { "uniprot_canonical_ac": "Q6IGP4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q6IGP4", "url": "https://www.uniprot.org/uniprotkb/Q6IGP4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 161, "chemical_mass": 18436.0, "gene_names": "HDC05792;BP1079;CG34054;Dmel\\CG34054;Dmel_CG34054;HDC05792", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q6IGP4-1" }, { "uniprot_canonical_ac": "Q6IHK7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q6IHK7", "url": "https://www.uniprot.org/uniprotkb/Q6IHK7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 64, "chemical_mass": 6840.0, "gene_names": "Dmel\\CG16824;CG16824;Dmel\\CG16824;Dmel_CG16824", "protein_name": "Translation machinery-associated protein 7 homolog", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q6IHK7-1" }, { "uniprot_canonical_ac": "Q6IHT7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q6IHT7", "url": "https://www.uniprot.org/uniprotkb/Q6IHT7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 121, "chemical_mass": 12824.0, "gene_names": "Sfp26Ad;CG42603;Dmel\\CG42603;Dmel_CG42603;FBgn0261055;Sfp26Ad", "protein_name": "", "disease": [], "biological_process": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "Q6IHT7", "url": "https://www.uniprot.org/uniprotkb/Q6IHT7" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q6IHT7", "url": "https://www.uniprot.org/uniprotkb/Q6IHT7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q6IHT7-1" }, { "uniprot_canonical_ac": "Q6IIF2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q6IIF2", "url": "https://www.uniprot.org/uniprotkb/Q6IIF2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 140, "chemical_mass": 15102.0, "gene_names": "inaF-C;CG34321;Dmel\\CG34321;Dmel_CG34321;INAF-C;INAF;InaF;inaF-C;inaF", "protein_name": "", "disease": [], "biological_process": [ { "name": "regulation of membrane potential", "id": "GO:0042391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042391", "evidence": [ { "database": "UniProtKB", "id": "Q6IIF2", "url": "https://www.uniprot.org/uniprotkb/Q6IIF2" } ], "pmid": "" }, { "name": "response to light stimulus", "id": "GO:0009416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009416", "evidence": [ { "database": "UniProtKB", "id": "Q6IIF2", "url": "https://www.uniprot.org/uniprotkb/Q6IIF2" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium channel regulator activity", "id": "GO:0005246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005246", "evidence": [ { "database": "UniProtKB", "id": "Q6IIF2", "url": "https://www.uniprot.org/uniprotkb/Q6IIF2" } ], "pmid": "" } ], "cellular_component": [ { "name": "rhabdomere", "id": "GO:0016028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016028", "evidence": [ { "database": "UniProtKB", "id": "Q6IIF2", "url": "https://www.uniprot.org/uniprotkb/Q6IIF2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q6IIF2-1" }, { "uniprot_canonical_ac": "Q6IIQ6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q6IIQ6", "url": "https://www.uniprot.org/uniprotkb/Q6IIQ6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 82, "chemical_mass": 7741.0, "gene_names": "Dmel\\CG43134;CG43134;Dmel\\CG43134;Dmel_CG43134", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q6IIQ6-1" }, { "uniprot_canonical_ac": "Q7K5K9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7K5K9", "url": "https://www.uniprot.org/uniprotkb/Q7K5K9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 534, "chemical_mass": 57779.0, "gene_names": "S-Lap8;CG4439;Dmel\\CG4439;FBgn0034132;S-LAP 8;S-Lap 8;S-Lap8;anon-WO0140519.41", "protein_name": "Crystallomitin S-Lap8", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q7K5K9", "url": "https://www.uniprot.org/uniprotkb/Q7K5K9" } ], "pmid": "" }, { "name": "major mitochondrial derivative", "id": "GO:0016008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016008", "evidence": [ { "database": "UniProtKB", "id": "Q7K5K9", "url": "https://www.uniprot.org/uniprotkb/Q7K5K9" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q7K5K9", "url": "https://www.uniprot.org/uniprotkb/Q7K5K9" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q7K5K9", "url": "https://www.uniprot.org/uniprotkb/Q7K5K9" } ], "pmid": "" }, { "name": "manganese ion binding", "id": "GO:0030145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030145", "evidence": [ { "database": "UniProtKB", "id": "Q7K5K9", "url": "https://www.uniprot.org/uniprotkb/Q7K5K9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7K5K9-1" }, { "uniprot_canonical_ac": "Q9V4C6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V4C6", "url": "https://www.uniprot.org/uniprotkb/Q9V4C6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 297, "chemical_mass": 31869.0, "gene_names": "Zip102B;CG2177;Dmel\\CG2177;Dmel_CG2177;ZIP102B;Zip102B;cg2177;dZip102B", "protein_name": "", "disease": [], "biological_process": [ { "name": "zinc ion transport", "id": "GO:0006829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006829", "evidence": [ { "database": "UniProtKB", "id": "Q9V4C6", "url": "https://www.uniprot.org/uniprotkb/Q9V4C6" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q9V4C6", "url": "https://www.uniprot.org/uniprotkb/Q9V4C6" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion transmembrane transporter activity", "id": "GO:0046873", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046873", "evidence": [ { "database": "UniProtKB", "id": "Q9V4C6", "url": "https://www.uniprot.org/uniprotkb/Q9V4C6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V4C6-1" }, { "uniprot_canonical_ac": "Q9I7I6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9I7I6", "url": "https://www.uniprot.org/uniprotkb/Q9I7I6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 552, "chemical_mass": 62010.0, "gene_names": "Dmel\\CG5191;CG5191;Dmel\\CG5191;Dmel_CG5191", "protein_name": "Amidase domain-containing protein", "disease": [ { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:9975", "name": "cocaine dependence", "description": "A drug dependence that is a psychological dependency on the regular use of cocaine.", "url": "https://disease-ontology.org/term/DOID:9975", "evidence": [ { "id": "9975", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9975" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "fatty acid amide hydrolase activity", "id": "GO:0017064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017064", "evidence": [ { "database": "UniProtKB", "id": "Q9I7I6", "url": "https://www.uniprot.org/uniprotkb/Q9I7I6" } ], "pmid": "" }, { "name": "monoacylglycerol lipase activity", "id": "GO:0047372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047372", "evidence": [ { "database": "UniProtKB", "id": "Q9I7I6", "url": "https://www.uniprot.org/uniprotkb/Q9I7I6" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid catabolic process", "id": "GO:0009062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009062", "evidence": [ { "database": "UniProtKB", "id": "Q9I7I6", "url": "https://www.uniprot.org/uniprotkb/Q9I7I6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9I7I6-1" }, { "uniprot_canonical_ac": "Q7KSB5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KSB5", "url": "https://www.uniprot.org/uniprotkb/Q7KSB5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 330, "chemical_mass": 36352.0, "gene_names": "Dmel\\CG4390;CG4390;Dmel\\CG4390;Dmel_CG4390", "protein_name": "S-formylglutathione hydrolase", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q7KSB5", "url": "https://www.uniprot.org/uniprotkb/Q7KSB5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q7KSB5", "url": "https://www.uniprot.org/uniprotkb/Q7KSB5" } ], "pmid": "" } ], "biological_process": [ { "name": "formaldehyde catabolic process", "id": "GO:0046294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046294", "evidence": [ { "database": "UniProtKB", "id": "Q7KSB5", "url": "https://www.uniprot.org/uniprotkb/Q7KSB5" } ], "pmid": "" } ], "molecular_function": [ { "name": "carboxylic ester hydrolase activity", "id": "GO:0052689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052689", "evidence": [ { "database": "UniProtKB", "id": "Q7KSB5", "url": "https://www.uniprot.org/uniprotkb/Q7KSB5" } ], "pmid": "" }, { "name": "serine hydrolase activity", "id": "GO:0017171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017171", "evidence": [ { "database": "UniProtKB", "id": "Q7KSB5", "url": "https://www.uniprot.org/uniprotkb/Q7KSB5" } ], "pmid": "" }, { "name": "S-formylglutathione hydrolase activity", "id": "GO:0018738", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018738", "evidence": [ { "database": "UniProtKB", "id": "Q7KSB5", "url": "https://www.uniprot.org/uniprotkb/Q7KSB5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7KSB5-1" }, { "uniprot_canonical_ac": "Q7KSP9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KSP9", "url": "https://www.uniprot.org/uniprotkb/Q7KSP9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 415, "chemical_mass": 48542.0, "gene_names": "Dmel\\CG14710;CG14710;Dmel\\CG14710;Dmel_CG14710", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q7KSP9", "url": "https://www.uniprot.org/uniprotkb/Q7KSP9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q7KSP9", "url": "https://www.uniprot.org/uniprotkb/Q7KSP9" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q7KSP9", "url": "https://www.uniprot.org/uniprotkb/Q7KSP9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q7KSP9", "url": "https://www.uniprot.org/uniprotkb/Q7KSP9" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "Q7KSP9", "url": "https://www.uniprot.org/uniprotkb/Q7KSP9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q7KSP9", "url": "https://www.uniprot.org/uniprotkb/Q7KSP9" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q7KSP9", "url": "https://www.uniprot.org/uniprotkb/Q7KSP9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q7KSP9", "url": "https://www.uniprot.org/uniprotkb/Q7KSP9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7KSP9-1" }, { "uniprot_canonical_ac": "Q7KT73-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KT73", "url": "https://www.uniprot.org/uniprotkb/Q7KT73" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 464, "chemical_mass": 51414.0, "gene_names": "Dmel\\CG18477;BG:DS07108.1;CG18477;CG31780;Dmel\\CG18477;Dmel\\CG31780;Dmel_CG18477;Dmel_CG31780;SPH69;cSPH231;cSPH69", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q7KT73", "url": "https://www.uniprot.org/uniprotkb/Q7KT73" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7KT73-1" }, { "uniprot_canonical_ac": "Q7KT83-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KT83", "url": "https://www.uniprot.org/uniprotkb/Q7KT83" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 299, "chemical_mass": 33896.0, "gene_names": "DS06874.6;BG:DS06874.6;CG18420;DS06874.6;Dmel\\CG18420;Dmel_CG18420;SPH111;SPH205", "protein_name": "Peptidase S1 domain-containing protein", "disease": [ { "disease_id": "DOID:1591", "name": "renovascular hypertension", "description": "", "url": "https://disease-ontology.org/term/DOID:1591", "evidence": [ { "id": "1591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1591" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q7KT83", "url": "https://www.uniprot.org/uniprotkb/Q7KT83" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q7KT83", "url": "https://www.uniprot.org/uniprotkb/Q7KT83" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q7KT83", "url": "https://www.uniprot.org/uniprotkb/Q7KT83" } ], "pmid": "" } ], "molecular_function": [ { "name": "serine-type peptidase activity", "id": "GO:0008236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008236", "evidence": [ { "database": "UniProtKB", "id": "Q7KT83", "url": "https://www.uniprot.org/uniprotkb/Q7KT83" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7KT83-1" }, { "uniprot_canonical_ac": "Q7KTF1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KTF1", "url": "https://www.uniprot.org/uniprotkb/Q7KTF1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 528, "chemical_mass": 57425.0, "gene_names": "Dmel\\CG7309;CG7309;Dmel\\CG7309;Dmel_CG7309", "protein_name": "Protein I'm not dead yet", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q7KTF1", "url": "https://www.uniprot.org/uniprotkb/Q7KTF1" } ], "pmid": "" } ], "biological_process": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "Q7KTF1", "url": "https://www.uniprot.org/uniprotkb/Q7KTF1" } ], "pmid": "" }, { "name": "citrate transport", "id": "GO:0015746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015746", "evidence": [ { "database": "UniProtKB", "id": "Q7KTF1", "url": "https://www.uniprot.org/uniprotkb/Q7KTF1" } ], "pmid": "" }, { "name": "succinate transport", "id": "GO:0015744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015744", "evidence": [ { "database": "UniProtKB", "id": "Q7KTF1", "url": "https://www.uniprot.org/uniprotkb/Q7KTF1" } ], "pmid": "" } ], "molecular_function": [ { "name": "citrate transmembrane transporter activity", "id": "GO:0015137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015137", "evidence": [ { "database": "UniProtKB", "id": "Q7KTF1", "url": "https://www.uniprot.org/uniprotkb/Q7KTF1" } ], "pmid": "" }, { "name": "succinate transmembrane transporter activity", "id": "GO:0015141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015141", "evidence": [ { "database": "UniProtKB", "id": "Q7KTF1", "url": "https://www.uniprot.org/uniprotkb/Q7KTF1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7KTF1-1" }, { "uniprot_canonical_ac": "Q7KTW3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KTW3", "url": "https://www.uniprot.org/uniprotkb/Q7KTW3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1115, "chemical_mass": 120883.0, "gene_names": "cg33288;CG33288;Dmel\\CG33288;Dmel_CG33288;cg33288", "protein_name": "X-linked retinitis pigmentosa GTPase regulator", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q7KTW3", "url": "https://www.uniprot.org/uniprotkb/Q7KTW3" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "Q7KTW3", "url": "https://www.uniprot.org/uniprotkb/Q7KTW3" } ], "pmid": "" }, { "name": "regulation of mitotic spindle assembly", "id": "GO:1901673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901673", "evidence": [ { "database": "UniProtKB", "id": "Q7KTW3", "url": "https://www.uniprot.org/uniprotkb/Q7KTW3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7KTW3-1", "start_pos": "523", "end_pos": "523", "site_lbl": "Thr523", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 523, "start_aa": "Thr", "end_pos": 523, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr523", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q7KTW3-1", "start_pos": "725", "end_pos": "725", "site_lbl": "Thr725", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 725, "start_aa": "Thr", "end_pos": 725, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr725", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q7KTW3-1" }, { "uniprot_canonical_ac": "Q7KU01-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KU01", "url": "https://www.uniprot.org/uniprotkb/Q7KU01" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1135, "chemical_mass": 120633.0, "gene_names": "PNUTS;CG31657;CG33526;CG4124;Dmel\\CG33526;Dmel_CG33526;PNUTS-RB;PNUTSDm;PNUTS;Pnuts;pnuts", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q7KU01", "url": "https://www.uniprot.org/uniprotkb/Q7KU01" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q7KU01", "url": "https://www.uniprot.org/uniprotkb/Q7KU01" } ], "pmid": "" }, { "name": "PTW/PP1 phosphatase complex", "id": "GO:0072357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072357", "evidence": [ { "database": "UniProtKB", "id": "Q7KU01", "url": "https://www.uniprot.org/uniprotkb/Q7KU01" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q7KU01", "url": "https://www.uniprot.org/uniprotkb/Q7KU01" } ], "pmid": "" }, { "name": "protein phosphatase 1 binding", "id": "GO:0008157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008157", "evidence": [ { "database": "UniProtKB", "id": "Q7KU01", "url": "https://www.uniprot.org/uniprotkb/Q7KU01" } ], "pmid": "" } ], "biological_process": [ { "name": "developmental growth", "id": "GO:0048589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048589", "evidence": [ { "database": "UniProtKB", "id": "Q7KU01", "url": "https://www.uniprot.org/uniprotkb/Q7KU01" } ], "pmid": "" }, { "name": "gene expression", "id": "GO:0010467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010467", "evidence": [ { "database": "UniProtKB", "id": "Q7KU01", "url": "https://www.uniprot.org/uniprotkb/Q7KU01" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7KU01-1", "start_pos": "446", "end_pos": "446", "site_lbl": "Thr446", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 446, "start_aa": "Thr", "end_pos": 446, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr446", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q7KU01-1" }, { "uniprot_canonical_ac": "Q7KU18-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KU18", "url": "https://www.uniprot.org/uniprotkb/Q7KU18" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 275, "chemical_mass": 32547.0, "gene_names": "Dmel\\CG15395;CG15395;Dmel\\CG15395;Dmel_CG15395", "protein_name": "TPX2 C-terminal domain-containing protein", "disease": [], "cellular_component": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "Q7KU18", "url": "https://www.uniprot.org/uniprotkb/Q7KU18" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7KU18-1" }, { "uniprot_canonical_ac": "Q7KUB3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KUB3", "url": "https://www.uniprot.org/uniprotkb/Q7KUB3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1616, "chemical_mass": 176966.0, "gene_names": "ImpE1;BcDNA:RE39082;CG13668;CG32356;CG7116;CT22003;CT33103;Dmel\\CG32356;Dmel_CG32356;IMP-E1;Imp-E1;ImpE1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extrinsic component of membrane", "id": "GO:0019898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019898", "evidence": [ { "database": "UniProtKB", "id": "Q7KUB3", "url": "https://www.uniprot.org/uniprotkb/Q7KUB3" } ], "pmid": "" } ], "biological_process": [ { "name": "imaginal disc eversion", "id": "GO:0007561", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007561", "evidence": [ { "database": "UniProtKB", "id": "Q7KUB3", "url": "https://www.uniprot.org/uniprotkb/Q7KUB3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7KUB3-1", "start_pos": "1325", "end_pos": "1325", "site_lbl": "Thr1325", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1325, "start_aa": "Thr", "end_pos": 1325, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1325", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q7KUB3-1", "start_pos": "1599", "end_pos": "1599", "site_lbl": "Thr1599", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1599, "start_aa": "Thr", "end_pos": 1599, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1599", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q7KUB3-1", "start_pos": "395", "end_pos": "395", "site_lbl": "Thr395", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 395, "start_aa": "Thr", "end_pos": 395, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr395", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q7KUB3-1", "start_pos": "668", "end_pos": "668", "site_lbl": "Thr668", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 668, "start_aa": "Thr", "end_pos": 668, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr668", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q7KUB3-1" }, { "uniprot_canonical_ac": "Q7KUG9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KUG9", "url": "https://www.uniprot.org/uniprotkb/Q7KUG9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 88, "chemical_mass": 9665.0, "gene_names": "Dmel\\CG33500;CG33500;Dmel\\CG33500;Dmel_CG33500;FBgn0053500", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7KUG9-1" }, { "uniprot_canonical_ac": "Q7KUM2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KUM2", "url": "https://www.uniprot.org/uniprotkb/Q7KUM2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 119, "chemical_mass": 13124.0, "gene_names": "CG7489;CG33259;CG7489;Dmel\\CG33259;Dmel_CG33259", "protein_name": "TIL domain-containing protein", "disease": [], "biological_process": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "Q7KUM2", "url": "https://www.uniprot.org/uniprotkb/Q7KUM2" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q7KUM2", "url": "https://www.uniprot.org/uniprotkb/Q7KUM2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7KUM2-1" }, { "uniprot_canonical_ac": "Q7KV62-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KV62", "url": "https://www.uniprot.org/uniprotkb/Q7KV62" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 47, "chemical_mass": 5362.0, "gene_names": "Rdh;CG14975;Dmel\\CG14975;Dmel_CG14975;Rdh", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7KV62-1" }, { "uniprot_canonical_ac": "Q7KVA7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KVA7", "url": "https://www.uniprot.org/uniprotkb/Q7KVA7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 3964, "chemical_mass": 455353.0, "gene_names": "Dhc62B;CG15804;CG18613;DHC7C;DHC;Dhc62B;Dhc;Dmel\\CG15804;Dmel_CG15804;dhc", "protein_name": "", "disease": [], "biological_process": [ { "name": "cilium movement involved in cell motility", "id": "GO:0060294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060294", "evidence": [ { "database": "UniProtKB", "id": "Q7KVA7", "url": "https://www.uniprot.org/uniprotkb/Q7KVA7" } ], "pmid": "" }, { "name": "retrograde axonal transport", "id": "GO:0008090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008090", "evidence": [ { "database": "UniProtKB", "id": "Q7KVA7", "url": "https://www.uniprot.org/uniprotkb/Q7KVA7" } ], "pmid": "" }, { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "Q7KVA7", "url": "https://www.uniprot.org/uniprotkb/Q7KVA7" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q7KVA7", "url": "https://www.uniprot.org/uniprotkb/Q7KVA7" } ], "pmid": "" }, { "name": "minus-end-directed microtubule motor activity", "id": "GO:0008569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008569", "evidence": [ { "database": "UniProtKB", "id": "Q7KVA7", "url": "https://www.uniprot.org/uniprotkb/Q7KVA7" } ], "pmid": "" }, { "name": "dynein light intermediate chain binding", "id": "GO:0051959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051959", "evidence": [ { "database": "UniProtKB", "id": "Q7KVA7", "url": "https://www.uniprot.org/uniprotkb/Q7KVA7" } ], "pmid": "" }, { "name": "dynein intermediate chain binding", "id": "GO:0045505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045505", "evidence": [ { "database": "UniProtKB", "id": "Q7KVA7", "url": "https://www.uniprot.org/uniprotkb/Q7KVA7" } ], "pmid": "" } ], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q7KVA7", "url": "https://www.uniprot.org/uniprotkb/Q7KVA7" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "Q7KVA7", "url": "https://www.uniprot.org/uniprotkb/Q7KVA7" } ], "pmid": "" }, { "name": "axon cytoplasm", "id": "GO:1904115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904115", "evidence": [ { "database": "UniProtKB", "id": "Q7KVA7", "url": "https://www.uniprot.org/uniprotkb/Q7KVA7" } ], "pmid": "" }, { "name": "inner dynein arm", "id": "GO:0036156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036156", "evidence": [ { "database": "UniProtKB", "id": "Q7KVA7", "url": "https://www.uniprot.org/uniprotkb/Q7KVA7" } ], "pmid": "" }, { "name": "9+2 motile cilium", "id": "GO:0097729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097729", "evidence": [ { "database": "UniProtKB", "id": "Q7KVA7", "url": "https://www.uniprot.org/uniprotkb/Q7KVA7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7KVA7-1", "start_pos": "1913", "end_pos": "1913", "site_lbl": "Thr1913", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1913, "start_aa": "Thr", "end_pos": 1913, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1913", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q7KVA7-1", "start_pos": "3347", "end_pos": "3347", "site_lbl": "Thr3347", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3347, "start_aa": "Thr", "end_pos": 3347, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3347", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q7KVA7-1", "start_pos": "3460", "end_pos": "3460", "site_lbl": "Thr3460", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3460, "start_aa": "Thr", "end_pos": 3460, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3460", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q7KVA7-1" }, { "uniprot_canonical_ac": "Q7KVW9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KVW9", "url": "https://www.uniprot.org/uniprotkb/Q7KVW9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 346, "chemical_mass": 39534.0, "gene_names": "SIP3;CG15468;Dmel\\CG15468;Dmel_CG15468", "protein_name": "Syntaxin interacting protein 3", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7KVW9-1" }, { "uniprot_canonical_ac": "Q7PL26-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7PL26", "url": "https://www.uniprot.org/uniprotkb/Q7PL26" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 226, "chemical_mass": 25655.0, "gene_names": "Maf1;CG40196;CR41604;Dmel\\CG40196;Dmel_CG40196;Maf1;Maf;dMaf1;maf1", "protein_name": "Repressor of RNA polymerase III transcription MAF1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q7PL26", "url": "https://www.uniprot.org/uniprotkb/Q7PL26" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q7PL26", "url": "https://www.uniprot.org/uniprotkb/Q7PL26" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase III", "id": "GO:0016480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016480", "evidence": [ { "database": "UniProtKB", "id": "Q7PL26", "url": "https://www.uniprot.org/uniprotkb/Q7PL26" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase III core binding", "id": "GO:0000994", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000994", "evidence": [ { "database": "UniProtKB", "id": "Q7PL26", "url": "https://www.uniprot.org/uniprotkb/Q7PL26" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7PL26-1" }, { "uniprot_canonical_ac": "Q7PLL7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7PLL7", "url": "https://www.uniprot.org/uniprotkb/Q7PLL7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 548, "chemical_mass": 61754.0, "gene_names": "DIP-lambda;40378;CG40378;CG42644;CG43676;CG45781;DIP-lambda;DIPlambda;Dmel\\CG45781;Dmel_CG45781", "protein_name": "", "disease": [ { "disease_id": "DOID:1070", "name": "primary open angle glaucoma", "description": "An open-angle glaucoma that is characterized by the absence of any apparent obstruction of aqueous outflow through the trabecular meshwork with gonioscopy, but often with elevated intraocular pressure.", "url": "https://disease-ontology.org/term/DOID:1070", "evidence": [ { "id": "1070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1070" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:13223", "name": "uterine fibroid", "description": "An uterine benign neoplasm derived from the smooth muscle layer of the uterus.", "url": "https://disease-ontology.org/term/DOID:13223", "evidence": [ { "id": "13223", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13223" } ], "weight": 0.0 }, { "disease_id": "DOID:2152", "name": "ovary epithelial cancer", "description": "An ovarian cancer that is derives_from ovarian surface epithelium.", "url": "https://disease-ontology.org/term/DOID:2152", "evidence": [ { "id": "2152", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2152" } ], "weight": 0.0 }, { "disease_id": "DOID:2394", "name": "ovarian cancer", "description": "A female reproductive organ cancer that is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:2394", "evidence": [ { "id": "2394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2394" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 } ], "biological_process": [ { "name": "establishment of synaptic specificity at neuromuscular junction", "id": "GO:0007529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007529", "evidence": [ { "database": "UniProtKB", "id": "Q7PLL7", "url": "https://www.uniprot.org/uniprotkb/Q7PLL7" } ], "pmid": "" } ], "cellular_component": [ { "name": "neuron projection membrane", "id": "GO:0032589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032589", "evidence": [ { "database": "UniProtKB", "id": "Q7PLL7", "url": "https://www.uniprot.org/uniprotkb/Q7PLL7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q7PLL7", "url": "https://www.uniprot.org/uniprotkb/Q7PLL7" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "Q7PLL7", "url": "https://www.uniprot.org/uniprotkb/Q7PLL7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q7PLL7-1" }, { "uniprot_canonical_ac": "Q86B58-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q86B58", "url": "https://www.uniprot.org/uniprotkb/Q86B58" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 284, "chemical_mass": 30915.0, "gene_names": "Dmel\\CG33127;CG33127;Dmel\\CG33127;Dmel_CG33127;SPH235", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q86B58", "url": "https://www.uniprot.org/uniprotkb/Q86B58" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q86B58", "url": "https://www.uniprot.org/uniprotkb/Q86B58" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q86B58-1" }, { "uniprot_canonical_ac": "Q86P97-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q86P97", "url": "https://www.uniprot.org/uniprotkb/Q86P97" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 422, "chemical_mass": 46051.0, "gene_names": "SppL;CG17370;CG5901;Dmel\\CG17370;Dmel_CG17370;SPPL3;SppL;Sppl;sppL", "protein_name": "Signal peptide peptidase-like", "disease": [], "cellular_component": [ { "name": "cytoplasmic side of endoplasmic reticulum membrane", "id": "GO:0098554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098554", "evidence": [ { "database": "UniProtKB", "id": "Q86P97", "url": "https://www.uniprot.org/uniprotkb/Q86P97" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q86P97", "url": "https://www.uniprot.org/uniprotkb/Q86P97" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q86P97", "url": "https://www.uniprot.org/uniprotkb/Q86P97" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q86P97", "url": "https://www.uniprot.org/uniprotkb/Q86P97" } ], "pmid": "" }, { "name": "Golgi-associated vesicle membrane", "id": "GO:0030660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030660", "evidence": [ { "database": "UniProtKB", "id": "Q86P97", "url": "https://www.uniprot.org/uniprotkb/Q86P97" } ], "pmid": "" }, { "name": "lumenal side of endoplasmic reticulum membrane", "id": "GO:0098553", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098553", "evidence": [ { "database": "UniProtKB", "id": "Q86P97", "url": "https://www.uniprot.org/uniprotkb/Q86P97" } ], "pmid": "" } ], "biological_process": [ { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "Q86P97", "url": "https://www.uniprot.org/uniprotkb/Q86P97" } ], "pmid": "" }, { "name": "membrane protein proteolysis", "id": "GO:0033619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033619", "evidence": [ { "database": "UniProtKB", "id": "Q86P97", "url": "https://www.uniprot.org/uniprotkb/Q86P97" } ], "pmid": "" } ], "molecular_function": [ { "name": "aspartic endopeptidase activity, intramembrane cleaving", "id": "GO:0042500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042500", "evidence": [ { "database": "UniProtKB", "id": "Q86P97", "url": "https://www.uniprot.org/uniprotkb/Q86P97" } ], "pmid": "" }, { "name": "signal peptidase activity", "id": "GO:0009003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009003", "evidence": [ { "database": "UniProtKB", "id": "Q86P97", "url": "https://www.uniprot.org/uniprotkb/Q86P97" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q86P97-1" }, { "uniprot_canonical_ac": "Q8I0J3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8I0J3", "url": "https://www.uniprot.org/uniprotkb/Q8I0J3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 87, "chemical_mass": 10633.0, "gene_names": "mRpS21;BcDNA:RE23482;CG32854;Dmel\\CG32854;Dmel_CG32854;MRP-S21;MrpS21;mRpS21", "protein_name": "", "disease": [], "cellular_component": [ { "name": "mitochondrial small ribosomal subunit", "id": "GO:0005763", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005763", "evidence": [ { "database": "UniProtKB", "id": "Q8I0J3", "url": "https://www.uniprot.org/uniprotkb/Q8I0J3" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "Q8I0J3", "url": "https://www.uniprot.org/uniprotkb/Q8I0J3" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial translation", "id": "GO:0032543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032543", "evidence": [ { "database": "UniProtKB", "id": "Q8I0J3", "url": "https://www.uniprot.org/uniprotkb/Q8I0J3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8I0J3-1" }, { "uniprot_canonical_ac": "Q8I936-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8I936", "url": "https://www.uniprot.org/uniprotkb/Q8I936" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 332, "chemical_mass": 38793.0, "gene_names": "CG10487;CG32413;Dmel\\CG32413;Dmel_CG32413", "protein_name": "glutaminyl-peptide cyclotransferase", "disease": [], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q8I936", "url": "https://www.uniprot.org/uniprotkb/Q8I936" } ], "pmid": "" }, { "name": "glutaminyl-peptide cyclotransferase activity", "id": "GO:0016603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016603", "evidence": [ { "database": "UniProtKB", "id": "Q8I936", "url": "https://www.uniprot.org/uniprotkb/Q8I936" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8I936-1" }, { "uniprot_canonical_ac": "Q8IME7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IME7", "url": "https://www.uniprot.org/uniprotkb/Q8IME7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 439, "chemical_mass": 50243.0, "gene_names": "tplus3b;CG31703;Dmel\\CG31703;Dmel_CG31703;tPlus3b;tplus3b", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q8IME7", "url": "https://www.uniprot.org/uniprotkb/Q8IME7" } ], "pmid": "" }, { "name": "RNA polymerase II C-terminal domain phosphoserine binding", "id": "GO:1990269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990269", "evidence": [ { "database": "UniProtKB", "id": "Q8IME7", "url": "https://www.uniprot.org/uniprotkb/Q8IME7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q8IME7", "url": "https://www.uniprot.org/uniprotkb/Q8IME7" } ], "pmid": "" }, { "name": "Cdc73/Paf1 complex", "id": "GO:0016593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016593", "evidence": [ { "database": "UniProtKB", "id": "Q8IME7", "url": "https://www.uniprot.org/uniprotkb/Q8IME7" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q8IME7", "url": "https://www.uniprot.org/uniprotkb/Q8IME7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IME7-1" }, { "uniprot_canonical_ac": "Q8IME8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IME8", "url": "https://www.uniprot.org/uniprotkb/Q8IME8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 441, "chemical_mass": 50441.0, "gene_names": "tplus3a;CG31702;Dmel\\CG31702;Dmel_CG31702;tPlus3a;tplus3a", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q8IME8", "url": "https://www.uniprot.org/uniprotkb/Q8IME8" } ], "pmid": "" }, { "name": "RNA polymerase II C-terminal domain phosphoserine binding", "id": "GO:1990269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990269", "evidence": [ { "database": "UniProtKB", "id": "Q8IME8", "url": "https://www.uniprot.org/uniprotkb/Q8IME8" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q8IME8", "url": "https://www.uniprot.org/uniprotkb/Q8IME8" } ], "pmid": "" } ], "cellular_component": [ { "name": "Cdc73/Paf1 complex", "id": "GO:0016593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016593", "evidence": [ { "database": "UniProtKB", "id": "Q8IME8", "url": "https://www.uniprot.org/uniprotkb/Q8IME8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IME8-1" }, { "uniprot_canonical_ac": "Q8IMK8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IMK8", "url": "https://www.uniprot.org/uniprotkb/Q8IMK8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 198, "chemical_mass": 21656.0, "gene_names": "Dmel\\CG31041;CG31041;Dmel\\CG31041;Dmel_CG31041", "protein_name": "Protein TsetseEP domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8IMK8-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Thr22", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 22, "start_aa": "Thr", "end_pos": 22, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr22", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q8IMK8-1" }, { "uniprot_canonical_ac": "Q8IMS4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IMS4", "url": "https://www.uniprot.org/uniprotkb/Q8IMS4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 405, "chemical_mass": 46894.0, "gene_names": "Dmel\\CG31380;CG31380;CG4964;Dmel\\CG31380;Dmel_CG31380;Dro27-0", "protein_name": "CHK kinase-like domain-containing protein", "disease": [], "molecular_function": [ { "name": "ecdysteroid 22-kinase activity", "id": "GO:0106389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106389", "evidence": [ { "database": "UniProtKB", "id": "Q8IMS4", "url": "https://www.uniprot.org/uniprotkb/Q8IMS4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IMS4-1" }, { "uniprot_canonical_ac": "Q8IMT2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IMT2", "url": "https://www.uniprot.org/uniprotkb/Q8IMT2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 400, "chemical_mass": 46191.0, "gene_names": "CG10551;CG10551;CG31099;Dmel\\CG31099;Dmel_CG31099;Dro14-0", "protein_name": "CHK kinase-like domain-containing protein", "disease": [], "molecular_function": [ { "name": "ecdysteroid 22-kinase activity", "id": "GO:0106389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106389", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT2", "url": "https://www.uniprot.org/uniprotkb/Q8IMT2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IMT2-1" }, { "uniprot_canonical_ac": "Q9VBZ0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBZ0", "url": "https://www.uniprot.org/uniprotkb/Q9VBZ0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 181, "chemical_mass": 20180.0, "gene_names": "Dmel\\CG11791;CG11791;Dmel\\CG11791;Dmel_CG11791", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VBZ0-1" }, { "uniprot_canonical_ac": "Q8IMY8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IMY8", "url": "https://www.uniprot.org/uniprotkb/Q8IMY8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 558, "chemical_mass": 65522.0, "gene_names": "Ir94f;94f;CG31225;DmelIR94f;Dmel\\CG31225;Dmel_CG31225;IR94f;Ir94f", "protein_name": "", "disease": [], "biological_process": [ { "name": "detection of chemical stimulus", "id": "GO:0009593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009593", "evidence": [ { "database": "UniProtKB", "id": "Q8IMY8", "url": "https://www.uniprot.org/uniprotkb/Q8IMY8" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q8IMY8", "url": "https://www.uniprot.org/uniprotkb/Q8IMY8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q8IMY8", "url": "https://www.uniprot.org/uniprotkb/Q8IMY8" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "Q8IMY8", "url": "https://www.uniprot.org/uniprotkb/Q8IMY8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8IMY8-1", "start_pos": "501", "end_pos": "501", "site_lbl": "Thr501", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 501, "start_aa": "Thr", "end_pos": 501, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr501", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q8IMY8-1" }, { "uniprot_canonical_ac": "Q8IN08-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IN08", "url": "https://www.uniprot.org/uniprotkb/Q8IN08" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 604, "chemical_mass": 69955.0, "gene_names": "Ir94c;94c;CG31423;DmelIR94c;Dmel\\CG31423;Dmel_CG31423;IR94c;Ir94c", "protein_name": "", "disease": [], "biological_process": [ { "name": "detection of chemical stimulus", "id": "GO:0009593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009593", "evidence": [ { "database": "UniProtKB", "id": "Q8IN08", "url": "https://www.uniprot.org/uniprotkb/Q8IN08" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q8IN08", "url": "https://www.uniprot.org/uniprotkb/Q8IN08" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q8IN08", "url": "https://www.uniprot.org/uniprotkb/Q8IN08" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "Q8IN08", "url": "https://www.uniprot.org/uniprotkb/Q8IN08" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8IN08-1", "start_pos": "168", "end_pos": "168", "site_lbl": "Thr168", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 168, "start_aa": "Thr", "end_pos": 168, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr168", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q8IN08-1" }, { "uniprot_canonical_ac": "Q8IN09-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IN09", "url": "https://www.uniprot.org/uniprotkb/Q8IN09" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 592, "chemical_mass": 69153.0, "gene_names": "Ir94b;94b;CG31424;DmelIR94b;Dmel\\CG31424;Dmel_CG31424;IR94b;Ir94b", "protein_name": "", "disease": [], "biological_process": [ { "name": "detection of chemical stimulus", "id": "GO:0009593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009593", "evidence": [ { "database": "UniProtKB", "id": "Q8IN09", "url": "https://www.uniprot.org/uniprotkb/Q8IN09" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q8IN09", "url": "https://www.uniprot.org/uniprotkb/Q8IN09" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q8IN09", "url": "https://www.uniprot.org/uniprotkb/Q8IN09" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "Q8IN09", "url": "https://www.uniprot.org/uniprotkb/Q8IN09" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IN09-1" }, { "uniprot_canonical_ac": "Q8IN25-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IN25", "url": "https://www.uniprot.org/uniprotkb/Q8IN25" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 940, "chemical_mass": 106734.0, "gene_names": "Dmel\\CG31198;CG31198;CG5845;Dmel\\CG31198;Dmel_CG31198;anon-WO0140519.12;anon-WO0140519.24", "protein_name": "Aminopeptidase", "disease": [ { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q8IN25", "url": "https://www.uniprot.org/uniprotkb/Q8IN25" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q8IN25", "url": "https://www.uniprot.org/uniprotkb/Q8IN25" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "Q8IN25", "url": "https://www.uniprot.org/uniprotkb/Q8IN25" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q8IN25", "url": "https://www.uniprot.org/uniprotkb/Q8IN25" } ], "pmid": "" }, { "name": "peptide catabolic process", "id": "GO:0043171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043171", "evidence": [ { "database": "UniProtKB", "id": "Q8IN25", "url": "https://www.uniprot.org/uniprotkb/Q8IN25" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q8IN25", "url": "https://www.uniprot.org/uniprotkb/Q8IN25" } ], "pmid": "" }, { "name": "metalloaminopeptidase activity", "id": "GO:0070006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070006", "evidence": [ { "database": "UniProtKB", "id": "Q8IN25", "url": "https://www.uniprot.org/uniprotkb/Q8IN25" } ], "pmid": "" }, { "name": "alanyl aminopeptidase activity", "id": "GO:0016285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016285", "evidence": [ { "database": "UniProtKB", "id": "Q8IN25", "url": "https://www.uniprot.org/uniprotkb/Q8IN25" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IN25-1" }, { "uniprot_canonical_ac": "Q8IN70-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IN70", "url": "https://www.uniprot.org/uniprotkb/Q8IN70" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 363, "chemical_mass": 41038.0, "gene_names": "CG16731;CG16731;CG31220;Dmel\\CG31220;Dmel_CG31220;SP6;c-SP6;cSP229", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "Q8IN70", "url": "https://www.uniprot.org/uniprotkb/Q8IN70" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q8IN70", "url": "https://www.uniprot.org/uniprotkb/Q8IN70" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q8IN70", "url": "https://www.uniprot.org/uniprotkb/Q8IN70" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q8IN70", "url": "https://www.uniprot.org/uniprotkb/Q8IN70" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q8IN70", "url": "https://www.uniprot.org/uniprotkb/Q8IN70" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IN70-1" }, { "uniprot_canonical_ac": "Q8INE2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8INE2", "url": "https://www.uniprot.org/uniprotkb/Q8INE2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 441, "chemical_mass": 51137.0, "gene_names": "CG31392;CG12258;CG31392;CG42726;Dmel\\CG42726;Dmel_CG42726;FBgn0051392", "protein_name": "C2H2-type domain-containing protein", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q8INE2", "url": "https://www.uniprot.org/uniprotkb/Q8INE2" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q8INE2", "url": "https://www.uniprot.org/uniprotkb/Q8INE2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q8INE2", "url": "https://www.uniprot.org/uniprotkb/Q8INE2" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q8INE2", "url": "https://www.uniprot.org/uniprotkb/Q8INE2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q8INE2", "url": "https://www.uniprot.org/uniprotkb/Q8INE2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q8INE2", "url": "https://www.uniprot.org/uniprotkb/Q8INE2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8INE2-1" }, { "uniprot_canonical_ac": "Q8INH7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8INH7", "url": "https://www.uniprot.org/uniprotkb/Q8INH7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1384, "chemical_mass": 159363.0, "gene_names": "timeout;CG14381;CG14382;CG7855;CG8148;Dmel\\CG7855;Dmel_CG7855;TIM2;Tim-2;dtim2;tim2;timeout;tim", "protein_name": "", "disease": [ { "disease_id": "DOID:0061006", "name": "advanced sleep phase syndrome 4", "description": "An advanced sleep phase syndrome that has_material_basis_in heterozygous mutation in the TIMELESS gene on chromosome 12q13.", "url": "https://disease-ontology.org/term/DOID:0061006", "evidence": [ { "id": "0061006", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061006" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 } ], "biological_process": [ { "name": "DNA replication checkpoint signaling", "id": "GO:0000076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000076", "evidence": [ { "database": "UniProtKB", "id": "Q8INH7", "url": "https://www.uniprot.org/uniprotkb/Q8INH7" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q8INH7", "url": "https://www.uniprot.org/uniprotkb/Q8INH7" } ], "pmid": "" }, { "name": "entrainment of circadian clock", "id": "GO:0009649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009649", "evidence": [ { "database": "UniProtKB", "id": "Q8INH7", "url": "https://www.uniprot.org/uniprotkb/Q8INH7" } ], "pmid": "" }, { "name": "DNA damage checkpoint signaling", "id": "GO:0000077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000077", "evidence": [ { "database": "UniProtKB", "id": "Q8INH7", "url": "https://www.uniprot.org/uniprotkb/Q8INH7" } ], "pmid": "" }, { "name": "replication fork arrest", "id": "GO:0043111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043111", "evidence": [ { "database": "UniProtKB", "id": "Q8INH7", "url": "https://www.uniprot.org/uniprotkb/Q8INH7" } ], "pmid": "" } ], "cellular_component": [ { "name": "replication fork protection complex", "id": "GO:0031298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031298", "evidence": [ { "database": "UniProtKB", "id": "Q8INH7", "url": "https://www.uniprot.org/uniprotkb/Q8INH7" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q8INH7", "url": "https://www.uniprot.org/uniprotkb/Q8INH7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8INH7-1" }, { "uniprot_canonical_ac": "Q8INK3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8INK3", "url": "https://www.uniprot.org/uniprotkb/Q8INK3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 157, "chemical_mass": 17137.0, "gene_names": "fabp;BcDNA:RH06221;BcDNA:RH46282;BcDNA:RH49003;BcDNA:SD12036;CG31305-PI;CG31305;CG6783;CT21061;Dmel\\CG6783;Dmel_CG6783;FABP;Fabp;anon-EST:Posey234;anon-WO0140519.12;dFABP;dFabp;fabp", "protein_name": "Fatty acid-binding protein, muscle", "disease": [ { "disease_id": "DOID:0111560", "name": "Charcot-Marie-Tooth disease type 1G", "description": "A Charcot-Marie-Tooth disease type 1 characterized by distal muscle weakness and atrophy with onset in the first or second decade of life that has_material_basis_in heterozygous mutation in the PMP2 gene on chromosome 8q21.13.", "url": "https://disease-ontology.org/term/DOID:0111560", "evidence": [ { "id": "0111560", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111560" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10591", "name": "pre-eclampsia", "description": "A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy.", "url": "https://disease-ontology.org/term/DOID:10591", "evidence": [ { "id": "10591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10591" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:14250", "name": "Down syndrome", "description": "A chromosomal duplication syndrome that is characterized by flat-looking facial features and weak muscle tone (hypotonia) in infancy and is caused by trisomy of all or a critical portion of chromosome 21 and is associated with intellectual disability.", "url": "https://disease-ontology.org/term/DOID:14250", "evidence": [ { "id": "14250", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14250" } ], "weight": 0.0 }, { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 }, { "disease_id": "DOID:1875", "name": "impotence", "description": "A sexual dysfunction that is characterized by persistent or recurrent inability to achieve or to maintain an erection during sexual activity.", "url": "https://disease-ontology.org/term/DOID:1875", "evidence": [ { "id": "1875", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1875" } ], "weight": 0.0 }, { "disease_id": "DOID:3068", "name": "glioblastoma", "description": "A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.", "url": "https://disease-ontology.org/term/DOID:3068", "evidence": [ { "id": "3068", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3068" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:767", "name": "muscular atrophy", "description": "", "url": "https://disease-ontology.org/term/DOID:767", "evidence": [ { "id": "767", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:767" } ], "weight": 0.0 }, { "disease_id": "DOID:8893", "name": "psoriasis", "description": "A skin disease that is characterized by patches of thick red skin and silvery scales.", "url": "https://disease-ontology.org/term/DOID:8893", "evidence": [ { "id": "8893", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8893" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "fatty acid binding", "id": "GO:0005504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005504", "evidence": [ { "database": "UniProtKB", "id": "Q8INK3", "url": "https://www.uniprot.org/uniprotkb/Q8INK3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q8INK3", "url": "https://www.uniprot.org/uniprotkb/Q8INK3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q8INK3", "url": "https://www.uniprot.org/uniprotkb/Q8INK3" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q8INK3", "url": "https://www.uniprot.org/uniprotkb/Q8INK3" } ], "pmid": "" } ], "biological_process": [ { "name": "long-term memory", "id": "GO:0007616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007616", "evidence": [ { "database": "UniProtKB", "id": "Q8INK3", "url": "https://www.uniprot.org/uniprotkb/Q8INK3" } ], "pmid": "" }, { "name": "fatty acid transport", "id": "GO:0015908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015908", "evidence": [ { "database": "UniProtKB", "id": "Q8INK3", "url": "https://www.uniprot.org/uniprotkb/Q8INK3" } ], "pmid": "" }, { "name": "chitin-based cuticle development", "id": "GO:0040003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040003", "evidence": [ { "database": "UniProtKB", "id": "Q8INK3", "url": "https://www.uniprot.org/uniprotkb/Q8INK3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8INK3-1" }, { "uniprot_canonical_ac": "Q8INM2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8INM2", "url": "https://www.uniprot.org/uniprotkb/Q8INM2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 249, "chemical_mass": 27169.0, "gene_names": "Dmel\\CG31406;BcDNA:AT13367;CG31406;Dmel\\CG31406;Dmel_CG31406", "protein_name": "", "disease": [], "biological_process": [ { "name": "notum morphogenesis", "id": "GO:0048802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048802", "evidence": [ { "database": "UniProtKB", "id": "Q8INM2", "url": "https://www.uniprot.org/uniprotkb/Q8INM2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8INM2-1" }, { "uniprot_canonical_ac": "Q8INX1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8INX1", "url": "https://www.uniprot.org/uniprotkb/Q8INX1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 182, "chemical_mass": 21029.0, "gene_names": "Dmel\\CG31800;CG31800;Dmel\\CG31800;Dmel_CG31800", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8INX1-1" }, { "uniprot_canonical_ac": "Q8INX4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8INX4", "url": "https://www.uniprot.org/uniprotkb/Q8INX4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 498, "chemical_mass": 58339.0, "gene_names": "Mst36Fa;CG15165;CG31801;Dmel\\CG31801;Dmel_CG31801;Mst36Fa;mst36Fa", "protein_name": "", "disease": [], "biological_process": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "Q8INX4", "url": "https://www.uniprot.org/uniprotkb/Q8INX4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8INX4-1" }, { "uniprot_canonical_ac": "Q8INX6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8INX6", "url": "https://www.uniprot.org/uniprotkb/Q8INX6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 117, "chemical_mass": 12580.0, "gene_names": "Dmel\\CG31789;CG31789;Dmel\\CG31789;Dmel_CG31789", "protein_name": "Salivary secreted peptide", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8INX6-1" }, { "uniprot_canonical_ac": "Q8INY2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8INY2", "url": "https://www.uniprot.org/uniprotkb/Q8INY2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 380, "chemical_mass": 44246.0, "gene_names": "Grl36b;CG31785;Dmel\\CG31785;Dmel_CG31785;Grl36b", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q8INY2", "url": "https://www.uniprot.org/uniprotkb/Q8INY2" } ], "pmid": "" } ], "biological_process": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "Q8INY2", "url": "https://www.uniprot.org/uniprotkb/Q8INY2" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated channel activity", "id": "GO:0022834", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022834", "evidence": [ { "database": "UniProtKB", "id": "Q8INY2", "url": "https://www.uniprot.org/uniprotkb/Q8INY2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8INY2-1" }, { "uniprot_canonical_ac": "Q8IP91-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IP91", "url": "https://www.uniprot.org/uniprotkb/Q8IP91" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 564, "chemical_mass": 64164.0, "gene_names": "d3635;3635;BcDNA:AT13596;BcDNA:LD05405;CG31759;Dmel\\CG31759;Dmel_CG31759;d3635;ms(2)01284", "protein_name": "2',5'-phosphodiesterase 12", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q8IP91", "url": "https://www.uniprot.org/uniprotkb/Q8IP91" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q8IP91", "url": "https://www.uniprot.org/uniprotkb/Q8IP91" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q8IP91", "url": "https://www.uniprot.org/uniprotkb/Q8IP91" } ], "pmid": "" }, { "name": "mitochondrial RNA 3'-end processing", "id": "GO:0000965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000965", "evidence": [ { "database": "UniProtKB", "id": "Q8IP91", "url": "https://www.uniprot.org/uniprotkb/Q8IP91" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "id": "GO:0000288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000288", "evidence": [ { "database": "UniProtKB", "id": "Q8IP91", "url": "https://www.uniprot.org/uniprotkb/Q8IP91" } ], "pmid": "" }, { "name": "mitochondrial mRNA catabolic process", "id": "GO:0000958", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000958", "evidence": [ { "database": "UniProtKB", "id": "Q8IP91", "url": "https://www.uniprot.org/uniprotkb/Q8IP91" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q8IP91", "url": "https://www.uniprot.org/uniprotkb/Q8IP91" } ], "pmid": "" }, { "name": "3'-5'-RNA exonuclease activity", "id": "GO:0000175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000175", "evidence": [ { "database": "UniProtKB", "id": "Q8IP91", "url": "https://www.uniprot.org/uniprotkb/Q8IP91" } ], "pmid": "" }, { "name": "poly(A)-specific ribonuclease activity", "id": "GO:0004535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004535", "evidence": [ { "database": "UniProtKB", "id": "Q8IP91", "url": "https://www.uniprot.org/uniprotkb/Q8IP91" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IP91-1" }, { "uniprot_canonical_ac": "Q8IP99-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IP99", "url": "https://www.uniprot.org/uniprotkb/Q8IP99" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 308, "chemical_mass": 35415.0, "gene_names": "Ada1-1;Ada1-1;Ada1;BcDNA:RE30472;CG31865;Dmel\\CG31865;ada1-1;dAda1", "protein_name": "Transcriptional adapter 1-1", "disease": [], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "Q8IP99", "url": "https://www.uniprot.org/uniprotkb/Q8IP99" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q8IP99", "url": "https://www.uniprot.org/uniprotkb/Q8IP99" } ], "pmid": "" }, { "name": "SAGA complex", "id": "GO:0000124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000124", "evidence": [ { "database": "UniProtKB", "id": "Q8IP99", "url": "https://www.uniprot.org/uniprotkb/Q8IP99" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q8IP99", "url": "https://www.uniprot.org/uniprotkb/Q8IP99" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q8IP99", "url": "https://www.uniprot.org/uniprotkb/Q8IP99" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "Q8IP99", "url": "https://www.uniprot.org/uniprotkb/Q8IP99" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IP99-1" }, { "uniprot_canonical_ac": "Q8IPA0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IPA0", "url": "https://www.uniprot.org/uniprotkb/Q8IPA0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 123, "chemical_mass": 13693.0, "gene_names": "Qtzl;CG17749;CG31864-PA;CG31864;Dmel\\CG31864;Dmel_CG31864;Qtzl", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IPA0-1" }, { "uniprot_canonical_ac": "Q8IPA8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IPA8", "url": "https://www.uniprot.org/uniprotkb/Q8IPA8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 305, "chemical_mass": 32415.0, "gene_names": "CG16917;CG32955;CG4831;CG16917;CG32831;CG32955-ORFB;CG32955;CG33695;CG4831;Dmel\\CG33695;Dmel_CG33695;l(2)k07716", "protein_name": "Chromatin complexes subunit BAP18", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q8IPA8", "url": "https://www.uniprot.org/uniprotkb/Q8IPA8" } ], "pmid": "" }, { "name": "MLL1 complex", "id": "GO:0071339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071339", "evidence": [ { "database": "UniProtKB", "id": "Q8IPA8", "url": "https://www.uniprot.org/uniprotkb/Q8IPA8" } ], "pmid": "" }, { "name": "NURF complex", "id": "GO:0016589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016589", "evidence": [ { "database": "UniProtKB", "id": "Q8IPA8", "url": "https://www.uniprot.org/uniprotkb/Q8IPA8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IPA8-1" }, { "uniprot_canonical_ac": "Q8IPB7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IPB7", "url": "https://www.uniprot.org/uniprotkb/Q8IPB7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1080, "chemical_mass": 122736.0, "gene_names": "LManII;BcDNA:GH02419;CG6206;Dmel\\CG6206;Dmel_CG6206;LM408;LManII;LM;dLM408;dLMII;dLManII;dLM", "protein_name": "Alpha-mannosidase", "disease": [ { "disease_id": "DOID:3413", "name": "alpha-mannosidosis", "description": "A lysosomal storage disease that has_material_basis_in deficiency of the alpha-D-manosidase enzyme resulting in the impairment of cell function from a build up of complex sugars derived from glycoproteins in the lysosome.", "url": "https://disease-ontology.org/term/DOID:3413", "evidence": [ { "id": "3413", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3413" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q8IPB7", "url": "https://www.uniprot.org/uniprotkb/Q8IPB7" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "Q8IPB7", "url": "https://www.uniprot.org/uniprotkb/Q8IPB7" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q8IPB7", "url": "https://www.uniprot.org/uniprotkb/Q8IPB7" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "Q8IPB7", "url": "https://www.uniprot.org/uniprotkb/Q8IPB7" } ], "pmid": "" }, { "name": "alpha-mannosidase activity", "id": "GO:0004559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004559", "evidence": [ { "database": "UniProtKB", "id": "Q8IPB7", "url": "https://www.uniprot.org/uniprotkb/Q8IPB7" } ], "pmid": "" }, { "name": "mannosyl-oligosaccharide 1,2-alpha-mannosidase activity", "id": "GO:0004571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004571", "evidence": [ { "database": "UniProtKB", "id": "Q8IPB7", "url": "https://www.uniprot.org/uniprotkb/Q8IPB7" } ], "pmid": "" } ], "biological_process": [ { "name": "mannose metabolic process", "id": "GO:0006013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006013", "evidence": [ { "database": "UniProtKB", "id": "Q8IPB7", "url": "https://www.uniprot.org/uniprotkb/Q8IPB7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IPB7-1" }, { "uniprot_canonical_ac": "Q8IPD5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IPD5", "url": "https://www.uniprot.org/uniprotkb/Q8IPD5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 340, "chemical_mass": 35507.0, "gene_names": "Cpr31A;CG33302;CG4791-PB;CG4791;Cpr31A;Dmel\\CG33302;Dmel_CG33302", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "Q8IPD5", "url": "https://www.uniprot.org/uniprotkb/Q8IPD5" } ], "pmid": "" }, { "name": "chitin-based extracellular matrix", "id": "GO:0062129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062129", "evidence": [ { "database": "UniProtKB", "id": "Q8IPD5", "url": "https://www.uniprot.org/uniprotkb/Q8IPD5" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of chitin-based larval cuticle", "id": "GO:0008010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008010", "evidence": [ { "database": "UniProtKB", "id": "Q8IPD5", "url": "https://www.uniprot.org/uniprotkb/Q8IPD5" } ], "pmid": "" } ], "biological_process": [ { "name": "chitin-based cuticle development", "id": "GO:0040003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040003", "evidence": [ { "database": "UniProtKB", "id": "Q8IPD5", "url": "https://www.uniprot.org/uniprotkb/Q8IPD5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IPD5-1" }, { "uniprot_canonical_ac": "Q8IPW1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IPW1", "url": "https://www.uniprot.org/uniprotkb/Q8IPW1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 805, "chemical_mass": 88273.0, "gene_names": "aru;CG4276;Dmel\\CG4276;Dmel_CG4276;EPS8L3;aru", "protein_name": "", "disease": [ { "disease_id": "DOID:0080261", "name": "autosomal recessive nonsyndromic deafness 106", "description": "An autosomal recessive nonsyndromic deafness that has_material_basis_in homozygous mutation in the EPS8L2 gene on chromosome 11p15.", "url": "https://disease-ontology.org/term/DOID:0080261", "evidence": [ { "id": "0080261", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080261" } ], "weight": 0.0 }, { "disease_id": "DOID:0110463", "name": "autosomal recessive nonsyndromic deafness 102", "description": "An autosomal recessive nonsyndromic deafness that has_material_basis_in mutation in the EPS8 gene on chromosome 12p12.", "url": "https://disease-ontology.org/term/DOID:0110463", "evidence": [ { "id": "0110463", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110463" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 } ], "biological_process": [ { "name": "olfactory behavior", "id": "GO:0042048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042048", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW1", "url": "https://www.uniprot.org/uniprotkb/Q8IPW1" } ], "pmid": "" }, { "name": "memory", "id": "GO:0007613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007613", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW1", "url": "https://www.uniprot.org/uniprotkb/Q8IPW1" } ], "pmid": "" }, { "name": "response to ethanol", "id": "GO:0045471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045471", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW1", "url": "https://www.uniprot.org/uniprotkb/Q8IPW1" } ], "pmid": "" }, { "name": "regulation of synapse structure or activity", "id": "GO:0050803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050803", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW1", "url": "https://www.uniprot.org/uniprotkb/Q8IPW1" } ], "pmid": "" }, { "name": "Rho protein signal transduction", "id": "GO:0007266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007266", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW1", "url": "https://www.uniprot.org/uniprotkb/Q8IPW1" } ], "pmid": "" }, { "name": "regulation of Rho protein signal transduction", "id": "GO:0035023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035023", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW1", "url": "https://www.uniprot.org/uniprotkb/Q8IPW1" } ], "pmid": "" } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW1", "url": "https://www.uniprot.org/uniprotkb/Q8IPW1" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW1", "url": "https://www.uniprot.org/uniprotkb/Q8IPW1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW1", "url": "https://www.uniprot.org/uniprotkb/Q8IPW1" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW1", "url": "https://www.uniprot.org/uniprotkb/Q8IPW1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8IPW1-1", "start_pos": "627", "end_pos": "627", "site_lbl": "Thr627", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 627, "start_aa": "Thr", "end_pos": 627, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr627", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q8IPW1-1", "start_pos": "766", "end_pos": "766", "site_lbl": "Thr766", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 766, "start_aa": "Thr", "end_pos": 766, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr766", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q8IPW1-1" }, { "uniprot_canonical_ac": "Q8IPW7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IPW7", "url": "https://www.uniprot.org/uniprotkb/Q8IPW7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 139, "chemical_mass": 16560.0, "gene_names": "Snrnp20;20K;CG31922;Dmel\\CG31922;Dmel_CG31922;anon-AE003587.1", "protein_name": "U1-C C2H2-type zinc finger domain-containing protein", "disease": [], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW7", "url": "https://www.uniprot.org/uniprotkb/Q8IPW7" } ], "pmid": "" } ], "cellular_component": [ { "name": "U11/U12 snRNP", "id": "GO:0034693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034693", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW7", "url": "https://www.uniprot.org/uniprotkb/Q8IPW7" } ], "pmid": "" }, { "name": "U12-type spliceosomal complex", "id": "GO:0005689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005689", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW7", "url": "https://www.uniprot.org/uniprotkb/Q8IPW7" } ], "pmid": "" } ], "biological_process": [ { "name": "alternative mRNA splicing, via spliceosome", "id": "GO:0000380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000380", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW7", "url": "https://www.uniprot.org/uniprotkb/Q8IPW7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IPW7-1" }, { "uniprot_canonical_ac": "Q8IPY7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IPY7", "url": "https://www.uniprot.org/uniprotkb/Q8IPY7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 264, "chemical_mass": 28828.0, "gene_names": "Dmel\\CG31681;CG31681;Dmel\\CG31681;Dmel_CG31681;SP230", "protein_name": "trypsin", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "Q8IPY7", "url": "https://www.uniprot.org/uniprotkb/Q8IPY7" } ], "pmid": "" }, { "name": "serine hydrolase activity", "id": "GO:0017171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017171", "evidence": [ { "database": "UniProtKB", "id": "Q8IPY7", "url": "https://www.uniprot.org/uniprotkb/Q8IPY7" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q8IPY7", "url": "https://www.uniprot.org/uniprotkb/Q8IPY7" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q8IPY7", "url": "https://www.uniprot.org/uniprotkb/Q8IPY7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IPY7-1" }, { "uniprot_canonical_ac": "Q8IPY9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IPY9", "url": "https://www.uniprot.org/uniprotkb/Q8IPY9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 319, "chemical_mass": 36055.0, "gene_names": "Tengl1;BcDNA:AT02809;CG17006;CG31682;Dmel\\CG31682;Dmel_CG31682;Tengl1", "protein_name": "", "disease": [ { "disease_id": "DOID:2316", "name": "brain ischemia", "description": "An ischemia that is characterized by insufficient blood flow to the brain to meet metabolic demand.", "url": "https://disease-ontology.org/term/DOID:2316", "evidence": [ { "id": "2316", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2316" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 }, { "disease_id": "DOID:767", "name": "muscular atrophy", "description": "", "url": "https://disease-ontology.org/term/DOID:767", "evidence": [ { "id": "767", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:767" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q8IPY9", "url": "https://www.uniprot.org/uniprotkb/Q8IPY9" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q8IPY9", "url": "https://www.uniprot.org/uniprotkb/Q8IPY9" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q8IPY9", "url": "https://www.uniprot.org/uniprotkb/Q8IPY9" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "Q8IPY9", "url": "https://www.uniprot.org/uniprotkb/Q8IPY9" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "Q8IPY9", "url": "https://www.uniprot.org/uniprotkb/Q8IPY9" } ], "pmid": "" }, { "name": "single-stranded DNA endodeoxyribonuclease activity", "id": "GO:0000014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000014", "evidence": [ { "database": "UniProtKB", "id": "Q8IPY9", "url": "https://www.uniprot.org/uniprotkb/Q8IPY9" } ], "pmid": "" } ], "biological_process": [ { "name": "apoptotic DNA fragmentation", "id": "GO:0006309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006309", "evidence": [ { "database": "UniProtKB", "id": "Q8IPY9", "url": "https://www.uniprot.org/uniprotkb/Q8IPY9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IPY9-1" }, { "uniprot_canonical_ac": "Q8IQ00-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQ00", "url": "https://www.uniprot.org/uniprotkb/Q8IQ00" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 789, "chemical_mass": 88715.0, "gene_names": "Dmel\\CG3277;CG3277;Dmel\\CG3277;Dmel_CG3277", "protein_name": "Protein kinase domain-containing protein", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ00", "url": "https://www.uniprot.org/uniprotkb/Q8IQ00" } ], "pmid": "" }, { "name": "transmembrane receptor protein tyrosine kinase activity", "id": "GO:0004714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004714", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ00", "url": "https://www.uniprot.org/uniprotkb/Q8IQ00" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ00", "url": "https://www.uniprot.org/uniprotkb/Q8IQ00" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ00", "url": "https://www.uniprot.org/uniprotkb/Q8IQ00" } ], "pmid": "" } ], "biological_process": [ { "name": "cell surface receptor protein tyrosine kinase signaling pathway", "id": "GO:0007169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007169", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ00", "url": "https://www.uniprot.org/uniprotkb/Q8IQ00" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8IQ00-1", "start_pos": "204", "end_pos": "204", "site_lbl": "Thr204", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 204, "start_aa": "Thr", "end_pos": 204, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr204", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q8IQ00-1" }, { "uniprot_canonical_ac": "Q8IQ80-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQ80", "url": "https://www.uniprot.org/uniprotkb/Q8IQ80" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 707, "chemical_mass": 77442.0, "gene_names": "pst;CG8588;Dm-65;Dmel\\CG8588;Dmel_CG8588;Pst;pst", "protein_name": "", "disease": [ { "disease_id": "DOID:934", "name": "viral infectious disease", "description": "A disease by infectious agent that results in infection, has_material_basis_in Viruses.", "url": "https://disease-ontology.org/term/DOID:934", "evidence": [ { "id": "934", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:934" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ80", "url": "https://www.uniprot.org/uniprotkb/Q8IQ80" } ], "pmid": "" } ], "biological_process": [ { "name": "long-term memory", "id": "GO:0007616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007616", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ80", "url": "https://www.uniprot.org/uniprotkb/Q8IQ80" } ], "pmid": "" }, { "name": "protein secretion", "id": "GO:0009306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009306", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ80", "url": "https://www.uniprot.org/uniprotkb/Q8IQ80" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IQ80-1" }, { "uniprot_canonical_ac": "Q8IQE8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQE8", "url": "https://www.uniprot.org/uniprotkb/Q8IQE8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 130, "chemical_mass": 13624.0, "gene_names": "nol;CG32077;Dmel\\CG32077;Dmel_CG32077;nol", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8IQE8-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Thr26", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 26, "start_aa": "Thr", "end_pos": 26, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr26", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q8IQE8-1" }, { "uniprot_canonical_ac": "Q8IQJ8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQJ8", "url": "https://www.uniprot.org/uniprotkb/Q8IQJ8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 484, "chemical_mass": 55217.0, "gene_names": "NEST:bs34d09;BcDNA:AT05691;CG32119;Dmel\\CG32119;Dmel_CG32119;NEST:bs34d09", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8IQJ8-1", "start_pos": "363", "end_pos": "363", "site_lbl": "Thr363", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 363, "start_aa": "Thr", "end_pos": 363, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr363", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q8IQJ8-1" }, { "uniprot_canonical_ac": "Q8IQM0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQM0", "url": "https://www.uniprot.org/uniprotkb/Q8IQM0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1023, "chemical_mass": 116698.0, "gene_names": "BcDNA:AT16542;Dmel\\CG13457;BcDNA:AT15860;BcDNA:AT16542;CG13457;Dmel\\CG13457;Dmel_CG13457", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IQM0-1" }, { "uniprot_canonical_ac": "Q8IQM1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQM1", "url": "https://www.uniprot.org/uniprotkb/Q8IQM1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 164, "chemical_mass": 18714.0, "gene_names": "Dmel\\CG32847;CG32847;Dmel\\CG32847;Dmel_CG32847", "protein_name": "RING-type E3 ubiquitin transferase", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q8IQM1", "url": "https://www.uniprot.org/uniprotkb/Q8IQM1" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q8IQM1", "url": "https://www.uniprot.org/uniprotkb/Q8IQM1" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q8IQM1", "url": "https://www.uniprot.org/uniprotkb/Q8IQM1" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "Q8IQM1", "url": "https://www.uniprot.org/uniprotkb/Q8IQM1" } ], "pmid": "" }, { "name": "ubiquitin-like protein conjugating enzyme binding", "id": "GO:0044390", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044390", "evidence": [ { "database": "UniProtKB", "id": "Q8IQM1", "url": "https://www.uniprot.org/uniprotkb/Q8IQM1" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q8IQM1", "url": "https://www.uniprot.org/uniprotkb/Q8IQM1" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "Q8IQM1", "url": "https://www.uniprot.org/uniprotkb/Q8IQM1" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "Q8IQM1", "url": "https://www.uniprot.org/uniprotkb/Q8IQM1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IQM1-1" }, { "uniprot_canonical_ac": "Q8IQN0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQN0", "url": "https://www.uniprot.org/uniprotkb/Q8IQN0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 351, "chemical_mass": 38364.0, "gene_names": "Dmel\\CG13073;CG13073;Dmel\\CG13073;Dmel_CG13073", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IQN0-1" }, { "uniprot_canonical_ac": "Q8IQR2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQR2", "url": "https://www.uniprot.org/uniprotkb/Q8IQR2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 419, "chemical_mass": 47771.0, "gene_names": "Dmel\\CG32182;CG32182;Dmel\\CG32182;Dmel_CG32182", "protein_name": "F-box domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IQR2-1" }, { "uniprot_canonical_ac": "Q8IQR9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQR9", "url": "https://www.uniprot.org/uniprotkb/Q8IQR9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 136, "chemical_mass": 15552.0, "gene_names": "Dmel\\CG32192;bs33g12.y1;CG32192;Dmel\\CG32192;Dmel_CG32192;NEST:bs33g12;NEST:bs36a12;bs33g12.y1", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IQR9-1" }, { "uniprot_canonical_ac": "Q8IQU7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQU7", "url": "https://www.uniprot.org/uniprotkb/Q8IQU7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 129, "chemical_mass": 12601.0, "gene_names": "825-Oak;825-Oak;CG32208;Dmel\\CG32208;Dmel_CG32208", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IQU7-1" }, { "uniprot_canonical_ac": "Q8IQV2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQV2", "url": "https://www.uniprot.org/uniprotkb/Q8IQV2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 432, "chemical_mass": 50386.0, "gene_names": "Dmel\\CG32221;CG32221;Dmel\\CG32221;Dmel_CG32221;FBXL18;anon-WO0118547.270", "protein_name": "F-box domain-containing protein", "disease": [], "cellular_component": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "Q8IQV2", "url": "https://www.uniprot.org/uniprotkb/Q8IQV2" } ], "pmid": "" } ], "biological_process": [ { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "Q8IQV2", "url": "https://www.uniprot.org/uniprotkb/Q8IQV2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IQV2-1" }, { "uniprot_canonical_ac": "Q8IQX3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQX3", "url": "https://www.uniprot.org/uniprotkb/Q8IQX3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 186, "chemical_mass": 20215.0, "gene_names": "Dmel\\CG32544;CG32544;Dmel\\CG32544;Dmel_CG32544", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IQX3-1" }, { "uniprot_canonical_ac": "Q8IR80-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IR80", "url": "https://www.uniprot.org/uniprotkb/Q8IR80" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 265, "chemical_mass": 29759.0, "gene_names": "Rab40;24641533;CG1900;DmRab40;Dmel\\CG1900;Dmel_CG1900;Q8IR80;Rab40;rab40", "protein_name": "", "disease": [], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q8IR80", "url": "https://www.uniprot.org/uniprotkb/Q8IR80" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q8IR80", "url": "https://www.uniprot.org/uniprotkb/Q8IR80" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q8IR80", "url": "https://www.uniprot.org/uniprotkb/Q8IR80" } ], "pmid": "" } ], "cellular_component": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "Q8IR80", "url": "https://www.uniprot.org/uniprotkb/Q8IR80" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q8IR80", "url": "https://www.uniprot.org/uniprotkb/Q8IR80" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q8IR80", "url": "https://www.uniprot.org/uniprotkb/Q8IR80" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "Q8IR80", "url": "https://www.uniprot.org/uniprotkb/Q8IR80" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "Q8IR80", "url": "https://www.uniprot.org/uniprotkb/Q8IR80" } ], "pmid": "" } ], "biological_process": [ { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "Q8IR80", "url": "https://www.uniprot.org/uniprotkb/Q8IR80" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "Q8IR80", "url": "https://www.uniprot.org/uniprotkb/Q8IR80" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "Q8IR80", "url": "https://www.uniprot.org/uniprotkb/Q8IR80" } ], "pmid": "" }, { "name": "Rab protein signal transduction", "id": "GO:0032482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032482", "evidence": [ { "database": "UniProtKB", "id": "Q8IR80", "url": "https://www.uniprot.org/uniprotkb/Q8IR80" } ], "pmid": "" }, { "name": "lipophagy", "id": "GO:0061724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061724", "evidence": [ { "database": "UniProtKB", "id": "Q8IR80", "url": "https://www.uniprot.org/uniprotkb/Q8IR80" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IR80-1" }, { "uniprot_canonical_ac": "Q8IRH9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IRH9", "url": "https://www.uniprot.org/uniprotkb/Q8IRH9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 517, "chemical_mass": 57100.0, "gene_names": "anon-WO0140519.53;BEST:GH19274;BEST:GH19464;CG32332;CG9130;Dmel\\CG9130;Dmel_CG9130;anon-WO0140519.145;anon-WO0140519.53", "protein_name": "Transcriptional cofactor Bfc domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IRH9-1" }, { "uniprot_canonical_ac": "Q8IRK5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IRK5", "url": "https://www.uniprot.org/uniprotkb/Q8IRK5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 316, "chemical_mass": 35722.0, "gene_names": "Dmel\\CG30289;CG30289;Dmel\\CG30289;Dmel_CG30289;SP226", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "Q8IRK5", "url": "https://www.uniprot.org/uniprotkb/Q8IRK5" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q8IRK5", "url": "https://www.uniprot.org/uniprotkb/Q8IRK5" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q8IRK5", "url": "https://www.uniprot.org/uniprotkb/Q8IRK5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8IRK5-1" }, { "uniprot_canonical_ac": "Q8MME9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8MME9", "url": "https://www.uniprot.org/uniprotkb/Q8MME9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 128, "chemical_mass": 14009.0, "gene_names": "CG13515;CG13515;CG30273;Dmel\\CG30273;Dmel_CG30273", "protein_name": "LITAF domain-containing protein", "disease": [ { "disease_id": "DOID:0110151", "name": "Charcot-Marie-Tooth disease type 1C", "description": "A Charcot-Marie-Tooth disease type 1 that has_material_basis_in heterozygous mutation in the LITAF gene on chromosome 16p13.", "url": "https://disease-ontology.org/term/DOID:0110151", "evidence": [ { "id": "0110151", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110151" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q8MME9", "url": "https://www.uniprot.org/uniprotkb/Q8MME9" } ], "pmid": "" } ], "cellular_component": [ { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "Q8MME9", "url": "https://www.uniprot.org/uniprotkb/Q8MME9" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "Q8MME9", "url": "https://www.uniprot.org/uniprotkb/Q8MME9" } ], "pmid": "" }, { "name": "cytoplasmic side of membrane", "id": "GO:0098562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098562", "evidence": [ { "database": "UniProtKB", "id": "Q8MME9", "url": "https://www.uniprot.org/uniprotkb/Q8MME9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q8MME9-1" }, { "uniprot_canonical_ac": "Q94883-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q94883", "url": "https://www.uniprot.org/uniprotkb/Q94883" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 709, "chemical_mass": 80727.0, "gene_names": "Dref;CG5838;DREF;DmDREF;Dmel\\CG5838;Dmel_CG5838;Dmel_DREF;Dref;dDREF;dref;p80/DREF;p80", "protein_name": "", "disease": [], "biological_process": [ { "name": "regulation of DNA biosynthetic process", "id": "GO:2000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000278", "evidence": [ { "database": "UniProtKB", "id": "Q94883", "url": "https://www.uniprot.org/uniprotkb/Q94883" } ], "pmid": "" }, { "name": "regulation of mitochondrial depolarization", "id": "GO:0051900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051900", "evidence": [ { "database": "UniProtKB", "id": "Q94883", "url": "https://www.uniprot.org/uniprotkb/Q94883" } ], "pmid": "" }, { "name": "compound eye development", "id": "GO:0048749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048749", "evidence": [ { "database": "UniProtKB", "id": "Q94883", "url": "https://www.uniprot.org/uniprotkb/Q94883" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q94883", "url": "https://www.uniprot.org/uniprotkb/Q94883" } ], "pmid": "" }, { "name": "protein phosphorylation", "id": "GO:0006468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006468", "evidence": [ { "database": "UniProtKB", "id": "Q94883", "url": "https://www.uniprot.org/uniprotkb/Q94883" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "Q94883", "url": "https://www.uniprot.org/uniprotkb/Q94883" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "Q94883", "url": "https://www.uniprot.org/uniprotkb/Q94883" } ], "pmid": "" }, { "name": "protein autophosphorylation", "id": "GO:0046777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046777", "evidence": [ { "database": "UniProtKB", "id": "Q94883", "url": "https://www.uniprot.org/uniprotkb/Q94883" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "Q94883", "url": "https://www.uniprot.org/uniprotkb/Q94883" } ], "pmid": "" }, { "name": "dendrite morphogenesis", "id": "GO:0048813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048813", "evidence": [ { "database": "UniProtKB", "id": "Q94883", "url": "https://www.uniprot.org/uniprotkb/Q94883" } ], "pmid": "" }, { "name": "DNA endoreduplication", "id": "GO:0042023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042023", "evidence": [ { "database": "UniProtKB", "id": "Q94883", "url": "https://www.uniprot.org/uniprotkb/Q94883" } ], "pmid": "" }, { "name": "compound eye morphogenesis", "id": "GO:0001745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001745", "evidence": [ { "database": "UniProtKB", "id": "Q94883", "url": "https://www.uniprot.org/uniprotkb/Q94883" } ], "pmid": "" }, { "name": "chaeta development", "id": "GO:0022416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022416", "evidence": [ { "database": "UniProtKB", "id": "Q94883", "url": "https://www.uniprot.org/uniprotkb/Q94883" } ], "pmid": "" }, { "name": "sensory organ precursor cell division", "id": "GO:0045035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045035", "evidence": [ { "database": "UniProtKB", "id": "Q94883", "url": "https://www.uniprot.org/uniprotkb/Q94883" } ], "pmid": "" }, { "name": "regulation of cell proliferation involved in compound eye morphogenesis", "id": "GO:2000495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000495", "evidence": [ { "database": "UniProtKB", "id": "Q94883", "url": "https://www.uniprot.org/uniprotkb/Q94883" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q94883", "url": "https://www.uniprot.org/uniprotkb/Q94883" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q94883", "url": "https://www.uniprot.org/uniprotkb/Q94883" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q94883", "url": "https://www.uniprot.org/uniprotkb/Q94883" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q94883", "url": "https://www.uniprot.org/uniprotkb/Q94883" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "Q94883", "url": "https://www.uniprot.org/uniprotkb/Q94883" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q94883", "url": "https://www.uniprot.org/uniprotkb/Q94883" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "Q94883", "url": "https://www.uniprot.org/uniprotkb/Q94883" } ], "pmid": "" }, { "name": "polytene chromosome", "id": "GO:0005700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005700", "evidence": [ { "database": "UniProtKB", "id": "Q94883", "url": "https://www.uniprot.org/uniprotkb/Q94883" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q94883-1" }, { "uniprot_canonical_ac": "Q9I7H4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9I7H4", "url": "https://www.uniprot.org/uniprotkb/Q9I7H4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 638, "chemical_mass": 69359.0, "gene_names": "Dmel\\CG9717;CG9717;Dmel\\CG9717;Dmel_CG9717", "protein_name": "Sodium-independent sulfate anion transporter", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9I7H4", "url": "https://www.uniprot.org/uniprotkb/Q9I7H4" } ], "pmid": "" } ], "biological_process": [ { "name": "chloride transmembrane transport", "id": "GO:1902476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902476", "evidence": [ { "database": "UniProtKB", "id": "Q9I7H4", "url": "https://www.uniprot.org/uniprotkb/Q9I7H4" } ], "pmid": "" }, { "name": "sulfate transmembrane transport", "id": "GO:1902358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902358", "evidence": [ { "database": "UniProtKB", "id": "Q9I7H4", "url": "https://www.uniprot.org/uniprotkb/Q9I7H4" } ], "pmid": "" } ], "molecular_function": [ { "name": "sulfate transmembrane transporter activity", "id": "GO:0015116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015116", "evidence": [ { "database": "UniProtKB", "id": "Q9I7H4", "url": "https://www.uniprot.org/uniprotkb/Q9I7H4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9I7H4-1", "start_pos": "144", "end_pos": "144", "site_lbl": "Thr144", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 144, "start_aa": "Thr", "end_pos": 144, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr144", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9I7H4-1" }, { "uniprot_canonical_ac": "Q9I7K8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9I7K8", "url": "https://www.uniprot.org/uniprotkb/Q9I7K8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 438, "chemical_mass": 48425.0, "gene_names": "Dmel\\CG18746;CG18746;Dmel\\CG18746;Dmel_CG18746", "protein_name": "Arrestin C-terminal-like domain-containing protein", "disease": [ { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:14525", "name": "Reye syndrome", "description": "A syndrome characterized by acute brain damage and liver function problems. It has been associated with aspirin consumption by children with viral illness, although it also occurs in the absence of aspirin use.", "url": "https://disease-ontology.org/term/DOID:14525", "evidence": [ { "id": "14525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14525" } ], "weight": 0.0 }, { "disease_id": "DOID:1686", "name": "glaucoma", "description": "An eye disease that is characterized by an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function.", "url": "https://disease-ontology.org/term/DOID:1686", "evidence": [ { "id": "1686", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1686" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "Q9I7K8", "url": "https://www.uniprot.org/uniprotkb/Q9I7K8" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "Q9I7K8", "url": "https://www.uniprot.org/uniprotkb/Q9I7K8" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9I7K8", "url": "https://www.uniprot.org/uniprotkb/Q9I7K8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9I7K8-1", "start_pos": "263", "end_pos": "263", "site_lbl": "Thr263", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 263, "start_aa": "Thr", "end_pos": 263, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr263", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9I7K8-1" }, { "uniprot_canonical_ac": "Q9I7L1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9I7L1", "url": "https://www.uniprot.org/uniprotkb/Q9I7L1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 418, "chemical_mass": 46351.0, "gene_names": "Dmel\\CG18747;CG18747;Dmel\\CG18747;Dmel_CG18747;Q9I7L1_DROME", "protein_name": "Arrestin C-terminal-like domain-containing protein", "disease": [ { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:14525", "name": "Reye syndrome", "description": "A syndrome characterized by acute brain damage and liver function problems. It has been associated with aspirin consumption by children with viral illness, although it also occurs in the absence of aspirin use.", "url": "https://disease-ontology.org/term/DOID:14525", "evidence": [ { "id": "14525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14525" } ], "weight": 0.0 }, { "disease_id": "DOID:1686", "name": "glaucoma", "description": "An eye disease that is characterized by an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function.", "url": "https://disease-ontology.org/term/DOID:1686", "evidence": [ { "id": "1686", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1686" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "Q9I7L1", "url": "https://www.uniprot.org/uniprotkb/Q9I7L1" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "Q9I7L1", "url": "https://www.uniprot.org/uniprotkb/Q9I7L1" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9I7L1", "url": "https://www.uniprot.org/uniprotkb/Q9I7L1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9I7L1-1", "start_pos": "301", "end_pos": "301", "site_lbl": "Thr301", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 301, "start_aa": "Thr", "end_pos": 301, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr301", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9I7L1-1", "start_pos": "399", "end_pos": "399", "site_lbl": "Thr399", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 399, "start_aa": "Thr", "end_pos": 399, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr399", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9I7L1-1" }, { "uniprot_canonical_ac": "Q9I7N9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9I7N9", "url": "https://www.uniprot.org/uniprotkb/Q9I7N9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 641, "chemical_mass": 72494.0, "gene_names": "CT42497;CG13796-PA;CG13796;CG18590;CT42497;Dmel\\CG13796;Dmel_CG13796", "protein_name": "Sodium- and chloride-dependent glycine transporter 1", "disease": [], "molecular_function": [ { "name": "neurotransmitter transmembrane transporter activity", "id": "GO:0005326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005326", "evidence": [ { "database": "UniProtKB", "id": "Q9I7N9", "url": "https://www.uniprot.org/uniprotkb/Q9I7N9" } ], "pmid": "" }, { "name": "neurotransmitter:sodium symporter activity", "id": "GO:0005328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005328", "evidence": [ { "database": "UniProtKB", "id": "Q9I7N9", "url": "https://www.uniprot.org/uniprotkb/Q9I7N9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9I7N9", "url": "https://www.uniprot.org/uniprotkb/Q9I7N9" } ], "pmid": "" }, { "name": "glycine:sodium symporter activity", "id": "GO:0015375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015375", "evidence": [ { "database": "UniProtKB", "id": "Q9I7N9", "url": "https://www.uniprot.org/uniprotkb/Q9I7N9" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9I7N9", "url": "https://www.uniprot.org/uniprotkb/Q9I7N9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9I7N9", "url": "https://www.uniprot.org/uniprotkb/Q9I7N9" } ], "pmid": "" } ], "biological_process": [ { "name": "amino acid transport", "id": "GO:0006865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006865", "evidence": [ { "database": "UniProtKB", "id": "Q9I7N9", "url": "https://www.uniprot.org/uniprotkb/Q9I7N9" } ], "pmid": "" }, { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "Q9I7N9", "url": "https://www.uniprot.org/uniprotkb/Q9I7N9" } ], "pmid": "" }, { "name": "neurotransmitter transport", "id": "GO:0006836", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006836", "evidence": [ { "database": "UniProtKB", "id": "Q9I7N9", "url": "https://www.uniprot.org/uniprotkb/Q9I7N9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9I7N9-1" }, { "uniprot_canonical_ac": "Q9I7R7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9I7R7", "url": "https://www.uniprot.org/uniprotkb/Q9I7R7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 362, "chemical_mass": 40369.0, "gene_names": "CG1809;CG1809;CG18809;Dmel\\CG18809;Dmel_CG18809", "protein_name": "CG18809", "disease": [], "molecular_function": [ { "name": "3'-5' exonuclease activity", "id": "GO:0008408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008408", "evidence": [ { "database": "UniProtKB", "id": "Q9I7R7", "url": "https://www.uniprot.org/uniprotkb/Q9I7R7" } ], "pmid": "" }, { "name": "5'-3' exonuclease activity", "id": "GO:0008409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008409", "evidence": [ { "database": "UniProtKB", "id": "Q9I7R7", "url": "https://www.uniprot.org/uniprotkb/Q9I7R7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9I7R7-1" }, { "uniprot_canonical_ac": "Q9U1K7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9U1K7", "url": "https://www.uniprot.org/uniprotkb/Q9U1K7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 135, "chemical_mass": 15634.0, "gene_names": "Dmel\\CG3939;BEST:SD07039;CG3939;Dmel\\CG3939;Dmel_CG3939;EG:140G11.5", "protein_name": "Thioredoxin domain-containing protein 17", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9U1K7", "url": "https://www.uniprot.org/uniprotkb/Q9U1K7" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-disulfide reductase [NAD(P)H] activity", "id": "GO:0047134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047134", "evidence": [ { "database": "UniProtKB", "id": "Q9U1K7", "url": "https://www.uniprot.org/uniprotkb/Q9U1K7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9U1K7-1" }, { "uniprot_canonical_ac": "Q9V395-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V395", "url": "https://www.uniprot.org/uniprotkb/Q9V395" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 477, "chemical_mass": 51901.0, "gene_names": "rtet;BcDNA:LD28419;CG5760;Dmel\\CG5760;Dmel_CG5760;Drtet;anon-WO0119857.1;l(3)07086;rtet", "protein_name": "", "disease": [ { "disease_id": "DOID:14503", "name": "neuronal ceroid lipofuscinosis", "description": "", "url": "https://disease-ontology.org/term/DOID:14503", "evidence": [ { "id": "14503", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14503" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9V395", "url": "https://www.uniprot.org/uniprotkb/Q9V395" } ], "pmid": "" }, { "name": "brush border membrane", "id": "GO:0031526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031526", "evidence": [ { "database": "UniProtKB", "id": "Q9V395", "url": "https://www.uniprot.org/uniprotkb/Q9V395" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "Q9V395", "url": "https://www.uniprot.org/uniprotkb/Q9V395" } ], "pmid": "" } ], "biological_process": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "Q9V395", "url": "https://www.uniprot.org/uniprotkb/Q9V395" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V395-1" }, { "uniprot_canonical_ac": "Q9V3C2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V3C2", "url": "https://www.uniprot.org/uniprotkb/Q9V3C2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 261, "chemical_mass": 29113.0, "gene_names": "RabX1;AAF47018;CG3870;Chrw;DmRabX1;Dmel\\CG3870;Dmel_CG3870;RAB5c;Rab31;RabX1;chrw;chr;l(2)k06908;rabX1", "protein_name": "", "disease": [], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q9V3C2", "url": "https://www.uniprot.org/uniprotkb/Q9V3C2" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q9V3C2", "url": "https://www.uniprot.org/uniprotkb/Q9V3C2" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "Q9V3C2", "url": "https://www.uniprot.org/uniprotkb/Q9V3C2" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "Q9V3C2", "url": "https://www.uniprot.org/uniprotkb/Q9V3C2" } ], "pmid": "" }, { "name": "positive regulation of protein catabolic process", "id": "GO:0045732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045732", "evidence": [ { "database": "UniProtKB", "id": "Q9V3C2", "url": "https://www.uniprot.org/uniprotkb/Q9V3C2" } ], "pmid": "" }, { "name": "Rab protein signal transduction", "id": "GO:0032482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032482", "evidence": [ { "database": "UniProtKB", "id": "Q9V3C2", "url": "https://www.uniprot.org/uniprotkb/Q9V3C2" } ], "pmid": "" }, { "name": "endosome membrane tubulation", "id": "GO:0097750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097750", "evidence": [ { "database": "UniProtKB", "id": "Q9V3C2", "url": "https://www.uniprot.org/uniprotkb/Q9V3C2" } ], "pmid": "" } ], "cellular_component": [ { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "Q9V3C2", "url": "https://www.uniprot.org/uniprotkb/Q9V3C2" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "Q9V3C2", "url": "https://www.uniprot.org/uniprotkb/Q9V3C2" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "Q9V3C2", "url": "https://www.uniprot.org/uniprotkb/Q9V3C2" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "Q9V3C2", "url": "https://www.uniprot.org/uniprotkb/Q9V3C2" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "Q9V3C2", "url": "https://www.uniprot.org/uniprotkb/Q9V3C2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V3C2-1" }, { "uniprot_canonical_ac": "Q9V3D7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V3D7", "url": "https://www.uniprot.org/uniprotkb/Q9V3D7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 83, "chemical_mass": 9329.0, "gene_names": "Dmel\\CG3713;BcDNA:GH13231;CG3713;Dmel\\CG3713;Dmel_CG3713;EG:BACR7A4.2", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V3D7-1" }, { "uniprot_canonical_ac": "Q9V3E3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V3E3", "url": "https://www.uniprot.org/uniprotkb/Q9V3E3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 189, "chemical_mass": 20927.0, "gene_names": "mRpL50;ANON-65Eb;BcDNA:GM06185;BcDNA:RE06140;CG8612;Dmel\\CG8612;Dmel_CG8612;MRP-L50;anon-65Eb;mRpL50", "protein_name": "Large ribosomal subunit protein mL50", "disease": [ { "disease_id": "DOID:5426", "name": "primary ovarian insufficiency", "description": "An ovarian disease where ovaries do not produce estrogen despite high levels of circulating gonadotropins in women under 40.", "url": "https://disease-ontology.org/term/DOID:5426", "evidence": [ { "id": "5426", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5426" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrial large ribosomal subunit", "id": "GO:0005762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005762", "evidence": [ { "database": "UniProtKB", "id": "Q9V3E3", "url": "https://www.uniprot.org/uniprotkb/Q9V3E3" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "Q9V3E3", "url": "https://www.uniprot.org/uniprotkb/Q9V3E3" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial translation", "id": "GO:0032543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032543", "evidence": [ { "database": "UniProtKB", "id": "Q9V3E3", "url": "https://www.uniprot.org/uniprotkb/Q9V3E3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V3E3-1" }, { "uniprot_canonical_ac": "Q9V3J5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V3J5", "url": "https://www.uniprot.org/uniprotkb/Q9V3J5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 558, "chemical_mass": 60985.0, "gene_names": "EG:BACR7A4.13;CG3690;Dmel\\CG3690;Dmel_CG3690;EG:BACR7A4.13;anon-WO0140519.250", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9V3J5", "url": "https://www.uniprot.org/uniprotkb/Q9V3J5" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "Q9V3J5", "url": "https://www.uniprot.org/uniprotkb/Q9V3J5" } ], "pmid": "" } ], "biological_process": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "Q9V3J5", "url": "https://www.uniprot.org/uniprotkb/Q9V3J5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V3J5-1" }, { "uniprot_canonical_ac": "Q9V3M3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V3M3", "url": "https://www.uniprot.org/uniprotkb/Q9V3M3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 254, "chemical_mass": 29322.0, "gene_names": "BG:BACR44L22.2;BACcr44L22.2;BG:BACR44L22.2;CG15254;Dmel\\CG15254;Dmel_CG15254", "protein_name": "Metalloendopeptidase", "disease": [], "molecular_function": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "Q9V3M3", "url": "https://www.uniprot.org/uniprotkb/Q9V3M3" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9V3M3", "url": "https://www.uniprot.org/uniprotkb/Q9V3M3" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9V3M3", "url": "https://www.uniprot.org/uniprotkb/Q9V3M3" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9V3M3", "url": "https://www.uniprot.org/uniprotkb/Q9V3M3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V3M3-1" }, { "uniprot_canonical_ac": "Q9V3N5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V3N5", "url": "https://www.uniprot.org/uniprotkb/Q9V3N5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 479, "chemical_mass": 53827.0, "gene_names": "Dmel\\CG10793;CG10793;Dmel\\CG10793;Dmel_CG10793;Indnc;indnc", "protein_name": "AAA+ ATPase domain-containing protein", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "microtubule severing ATPase activity", "id": "GO:0008568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008568", "evidence": [ { "database": "UniProtKB", "id": "Q9V3N5", "url": "https://www.uniprot.org/uniprotkb/Q9V3N5" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9V3N5", "url": "https://www.uniprot.org/uniprotkb/Q9V3N5" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q9V3N5", "url": "https://www.uniprot.org/uniprotkb/Q9V3N5" } ], "pmid": "" } ], "biological_process": [ { "name": "microtubule severing", "id": "GO:0051013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051013", "evidence": [ { "database": "UniProtKB", "id": "Q9V3N5", "url": "https://www.uniprot.org/uniprotkb/Q9V3N5" } ], "pmid": "" }, { "name": "meiotic spindle organization", "id": "GO:0000212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000212", "evidence": [ { "database": "UniProtKB", "id": "Q9V3N5", "url": "https://www.uniprot.org/uniprotkb/Q9V3N5" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9V3N5", "url": "https://www.uniprot.org/uniprotkb/Q9V3N5" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "Q9V3N5", "url": "https://www.uniprot.org/uniprotkb/Q9V3N5" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q9V3N5", "url": "https://www.uniprot.org/uniprotkb/Q9V3N5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V3N5-1" }, { "uniprot_canonical_ac": "Q9V3N9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V3N9", "url": "https://www.uniprot.org/uniprotkb/Q9V3N9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 558, "chemical_mass": 60537.0, "gene_names": "b6;B6;CG3100;Dmel\\CG3100;Dmel_CG3100;EG:9D2.1;b6", "protein_name": "", "disease": [ { "disease_id": "DOID:1441", "name": "autosomal dominant cerebellar ataxia", "description": "A cerebellar ataxia that has_material_basis_in autosomal dominant inheritance.", "url": "https://disease-ontology.org/term/DOID:1441", "evidence": [ { "id": "1441", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1441" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "Q9V3N9", "url": "https://www.uniprot.org/uniprotkb/Q9V3N9" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9V3N9", "url": "https://www.uniprot.org/uniprotkb/Q9V3N9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9V3N9-1", "start_pos": "356", "end_pos": "356", "site_lbl": "Thr356", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 356, "start_aa": "Thr", "end_pos": 356, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr356", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9V3N9-1" }, { "uniprot_canonical_ac": "Q9V3V1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V3V1", "url": "https://www.uniprot.org/uniprotkb/Q9V3V1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 141, "chemical_mass": 15510.0, "gene_names": "EG:BACR42I17.12;CG14628;Dmel\\CG14628;Dmel_CG14628;EG:BACR42I17.12;cg14628", "protein_name": "RRM domain-containing protein", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q9V3V1", "url": "https://www.uniprot.org/uniprotkb/Q9V3V1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V3V1-1" }, { "uniprot_canonical_ac": "Q9V3V9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V3V9", "url": "https://www.uniprot.org/uniprotkb/Q9V3V9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 359, "chemical_mass": 40614.0, "gene_names": "EndoGI;BG:DS07473.2;CG4930;Dmel\\CG4930;Dmel_CG4930;EndoGI;dEndoGI;endoGI", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9V3V9", "url": "https://www.uniprot.org/uniprotkb/Q9V3V9" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of Notch signaling pathway", "id": "GO:0045747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045747", "evidence": [ { "database": "UniProtKB", "id": "Q9V3V9", "url": "https://www.uniprot.org/uniprotkb/Q9V3V9" } ], "pmid": "" } ], "molecular_function": [ { "name": "ribonuclease inhibitor activity", "id": "GO:0008428", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008428", "evidence": [ { "database": "UniProtKB", "id": "Q9V3V9", "url": "https://www.uniprot.org/uniprotkb/Q9V3V9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V3V9-1" }, { "uniprot_canonical_ac": "Q9V3X8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V3X8", "url": "https://www.uniprot.org/uniprotkb/Q9V3X8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 329, "chemical_mass": 37653.0, "gene_names": "EG:BACR42I17.11;CG11398;Dmel\\CG11398;Dmel_CG11398;EG:BACR42I17.11", "protein_name": "C2H2-type domain-containing protein", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "Q9V3X8", "url": "https://www.uniprot.org/uniprotkb/Q9V3X8" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q9V3X8", "url": "https://www.uniprot.org/uniprotkb/Q9V3X8" } ], "pmid": "" }, { "name": "dendrite morphogenesis", "id": "GO:0048813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048813", "evidence": [ { "database": "UniProtKB", "id": "Q9V3X8", "url": "https://www.uniprot.org/uniprotkb/Q9V3X8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9V3X8", "url": "https://www.uniprot.org/uniprotkb/Q9V3X8" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9V3X8", "url": "https://www.uniprot.org/uniprotkb/Q9V3X8" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "Q9V3X8", "url": "https://www.uniprot.org/uniprotkb/Q9V3X8" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "Q9V3X8", "url": "https://www.uniprot.org/uniprotkb/Q9V3X8" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q9V3X8", "url": "https://www.uniprot.org/uniprotkb/Q9V3X8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q9V3X8", "url": "https://www.uniprot.org/uniprotkb/Q9V3X8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V3X8-1" }, { "uniprot_canonical_ac": "Q9V3Y4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V3Y4", "url": "https://www.uniprot.org/uniprotkb/Q9V3Y4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 316, "chemical_mass": 35012.0, "gene_names": "Mtch;CG6851;Dmel\\CG6851;Dmel_CG6851;Mtch", "protein_name": "", "disease": [ { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:5426", "name": "primary ovarian insufficiency", "description": "An ovarian disease where ovaries do not produce estrogen despite high levels of circulating gonadotropins in women under 40.", "url": "https://disease-ontology.org/term/DOID:5426", "evidence": [ { "id": "5426", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5426" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9V3Y4", "url": "https://www.uniprot.org/uniprotkb/Q9V3Y4" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "Q9V3Y4", "url": "https://www.uniprot.org/uniprotkb/Q9V3Y4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V3Y4-1" }, { "uniprot_canonical_ac": "Q9V402-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V402", "url": "https://www.uniprot.org/uniprotkb/Q9V402" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 240, "chemical_mass": 27192.0, "gene_names": "BACR44L22.4;BACR44L22.4;BG:BACR44L22.4;CG11865;Dmel\\CG11865;Dmel_CG11865", "protein_name": "Metalloendopeptidase", "disease": [], "molecular_function": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "Q9V402", "url": "https://www.uniprot.org/uniprotkb/Q9V402" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9V402", "url": "https://www.uniprot.org/uniprotkb/Q9V402" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9V402", "url": "https://www.uniprot.org/uniprotkb/Q9V402" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9V402", "url": "https://www.uniprot.org/uniprotkb/Q9V402" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V402-1" }, { "uniprot_canonical_ac": "Q9V414-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V414", "url": "https://www.uniprot.org/uniprotkb/Q9V414" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1177, "chemical_mass": 135314.0, "gene_names": "Smg5;BG:DS08220.2;CG8954;Dmel\\CG8954;Dmel_CG8954;SMG5;Smg5 nonsense RNA decay factor;Smg5;anon-34Ea;br31;dSMG5;l(2)34Eb;l(2)br31;l34Eb;smg5", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9V414", "url": "https://www.uniprot.org/uniprotkb/Q9V414" } ], "pmid": "" }, { "name": "telomerase holoenzyme complex", "id": "GO:0005697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005697", "evidence": [ { "database": "UniProtKB", "id": "Q9V414", "url": "https://www.uniprot.org/uniprotkb/Q9V414" } ], "pmid": "" } ], "molecular_function": [ { "name": "telomeric DNA binding", "id": "GO:0042162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042162", "evidence": [ { "database": "UniProtKB", "id": "Q9V414", "url": "https://www.uniprot.org/uniprotkb/Q9V414" } ], "pmid": "" }, { "name": "telomerase RNA binding", "id": "GO:0070034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070034", "evidence": [ { "database": "UniProtKB", "id": "Q9V414", "url": "https://www.uniprot.org/uniprotkb/Q9V414" } ], "pmid": "" } ], "biological_process": [ { "name": "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "id": "GO:0000184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000184", "evidence": [ { "database": "UniProtKB", "id": "Q9V414", "url": "https://www.uniprot.org/uniprotkb/Q9V414" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V414-1" }, { "uniprot_canonical_ac": "Q9V415-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V415", "url": "https://www.uniprot.org/uniprotkb/Q9V415" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 819, "chemical_mass": 89361.0, "gene_names": "Hrd3;BcDNA:LD23587;CG10221;Dmel\\CG10221;Dmel_CG10221;HRD3;Hrd3;hrd3", "protein_name": "", "disease": [ { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9V415", "url": "https://www.uniprot.org/uniprotkb/Q9V415" } ], "pmid": "" } ], "biological_process": [ { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "Q9V415", "url": "https://www.uniprot.org/uniprotkb/Q9V415" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9V415-1", "start_pos": "765", "end_pos": "765", "site_lbl": "Thr765", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 765, "start_aa": "Thr", "end_pos": 765, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr765", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9V415-1" }, { "uniprot_canonical_ac": "Q9V4C0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V4C0", "url": "https://www.uniprot.org/uniprotkb/Q9V4C0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 463, "chemical_mass": 53398.0, "gene_names": "yellow-h;CG1629;DPT;Dmel\\CG1629;yell-h;yellow-h", "protein_name": "Dopaminechrome tautomerase", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9V4C0", "url": "https://www.uniprot.org/uniprotkb/Q9V4C0" } ], "pmid": "" } ], "biological_process": [ { "name": "melanin biosynthetic process from tyrosine", "id": "GO:0006583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006583", "evidence": [ { "database": "UniProtKB", "id": "Q9V4C0", "url": "https://www.uniprot.org/uniprotkb/Q9V4C0" } ], "pmid": "" } ], "molecular_function": [ { "name": "dopaminechrome tautomerase activity", "id": "GO:0106417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106417", "evidence": [ { "database": "UniProtKB", "id": "Q9V4C0", "url": "https://www.uniprot.org/uniprotkb/Q9V4C0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V4C0-1" }, { "uniprot_canonical_ac": "Q9V4D8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V4D8", "url": "https://www.uniprot.org/uniprotkb/Q9V4D8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1738, "chemical_mass": 191423.0, "gene_names": "Tdg;1981;CG1981;Dmel\\CG1981;Dmel_CG1981;G/T-mismatch-specific-thymine-DNA-glycosylase;MUG;TDG;THD1;Tdg;Thd1;UDG_DM_7304305;dmThd1p;thd1", "protein_name": "G/T mismatch-specific thymine DNA glycosylase", "disease": [], "molecular_function": [ { "name": "G/U mismatch-specific uracil-DNA glycosylase activity", "id": "GO:0043739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043739", "evidence": [ { "database": "UniProtKB", "id": "Q9V4D8", "url": "https://www.uniprot.org/uniprotkb/Q9V4D8" } ], "pmid": "" }, { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "Q9V4D8", "url": "https://www.uniprot.org/uniprotkb/Q9V4D8" } ], "pmid": "" }, { "name": "uracil DNA N-glycosylase activity", "id": "GO:0004844", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004844", "evidence": [ { "database": "UniProtKB", "id": "Q9V4D8", "url": "https://www.uniprot.org/uniprotkb/Q9V4D8" } ], "pmid": "" }, { "name": "SUMO binding", "id": "GO:0032183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032183", "evidence": [ { "database": "UniProtKB", "id": "Q9V4D8", "url": "https://www.uniprot.org/uniprotkb/Q9V4D8" } ], "pmid": "" }, { "name": "pyrimidine-specific mismatch base pair DNA N-glycosylase activity", "id": "GO:0008263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008263", "evidence": [ { "database": "UniProtKB", "id": "Q9V4D8", "url": "https://www.uniprot.org/uniprotkb/Q9V4D8" } ], "pmid": "" }, { "name": "G/T mismatch-specific thymine-DNA glycosylase activity", "id": "GO:0141016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141016", "evidence": [ { "database": "UniProtKB", "id": "Q9V4D8", "url": "https://www.uniprot.org/uniprotkb/Q9V4D8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9V4D8", "url": "https://www.uniprot.org/uniprotkb/Q9V4D8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q9V4D8", "url": "https://www.uniprot.org/uniprotkb/Q9V4D8" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9V4D8", "url": "https://www.uniprot.org/uniprotkb/Q9V4D8" } ], "pmid": "" }, { "name": "mismatch repair", "id": "GO:0006298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006298", "evidence": [ { "database": "UniProtKB", "id": "Q9V4D8", "url": "https://www.uniprot.org/uniprotkb/Q9V4D8" } ], "pmid": "" }, { "name": "epigenetic regulation of gene expression", "id": "GO:0040029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040029", "evidence": [ { "database": "UniProtKB", "id": "Q9V4D8", "url": "https://www.uniprot.org/uniprotkb/Q9V4D8" } ], "pmid": "" }, { "name": "base-excision repair, AP site formation", "id": "GO:0006285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006285", "evidence": [ { "database": "UniProtKB", "id": "Q9V4D8", "url": "https://www.uniprot.org/uniprotkb/Q9V4D8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V4D8-1" }, { "uniprot_canonical_ac": "Q9V9M6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V9M6", "url": "https://www.uniprot.org/uniprotkb/Q9V9M6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 611, "chemical_mass": 70749.0, "gene_names": "Tif-IA;CG16938;CG3278;CG5951;Dmel\\CG3278;RRN3;TIF-1A;TIF-IA;TIF1A;TIf-IA;Tif-1A;Tif-1a;Tif-IA;TifIA;dTIF-IA;tif1a", "protein_name": "RNA polymerase I-specific transcription initiation factor Tif-IA", "disease": [ { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9V9M6", "url": "https://www.uniprot.org/uniprotkb/Q9V9M6" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q9V9M6", "url": "https://www.uniprot.org/uniprotkb/Q9V9M6" } ], "pmid": "" } ], "biological_process": [ { "name": "determination of adult lifespan", "id": "GO:0008340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008340", "evidence": [ { "database": "UniProtKB", "id": "Q9V9M6", "url": "https://www.uniprot.org/uniprotkb/Q9V9M6" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase I promoter", "id": "GO:0006361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006361", "evidence": [ { "database": "UniProtKB", "id": "Q9V9M6", "url": "https://www.uniprot.org/uniprotkb/Q9V9M6" } ], "pmid": "" }, { "name": "nucleolar large rRNA transcription by RNA polymerase I", "id": "GO:0042790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042790", "evidence": [ { "database": "UniProtKB", "id": "Q9V9M6", "url": "https://www.uniprot.org/uniprotkb/Q9V9M6" } ], "pmid": "" }, { "name": "female germ-line stem cell population maintenance", "id": "GO:0036099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036099", "evidence": [ { "database": "UniProtKB", "id": "Q9V9M6", "url": "https://www.uniprot.org/uniprotkb/Q9V9M6" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase I general transcription initiation factor activity", "id": "GO:0001181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001181", "evidence": [ { "database": "UniProtKB", "id": "Q9V9M6", "url": "https://www.uniprot.org/uniprotkb/Q9V9M6" } ], "pmid": "" }, { "name": "RNA polymerase I core binding", "id": "GO:0001042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001042", "evidence": [ { "database": "UniProtKB", "id": "Q9V9M6", "url": "https://www.uniprot.org/uniprotkb/Q9V9M6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9V9M6-1", "start_pos": "205", "end_pos": "205", "site_lbl": "Thr205", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 205, "start_aa": "Thr", "end_pos": 205, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr205", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9V9M6-1" }, { "uniprot_canonical_ac": "Q9V9T1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V9T1", "url": "https://www.uniprot.org/uniprotkb/Q9V9T1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 773, "chemical_mass": 87090.0, "gene_names": "CG2112;CG11574;CG2112;CG42233;Dmel\\CG42233;Dmel_CG42233", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9V9T1", "url": "https://www.uniprot.org/uniprotkb/Q9V9T1" } ], "pmid": "" }, { "name": "Cul4-RING E3 ubiquitin ligase complex", "id": "GO:0080008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080008", "evidence": [ { "database": "UniProtKB", "id": "Q9V9T1", "url": "https://www.uniprot.org/uniprotkb/Q9V9T1" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of fatty acid biosynthetic process", "id": "GO:0045717", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045717", "evidence": [ { "database": "UniProtKB", "id": "Q9V9T1", "url": "https://www.uniprot.org/uniprotkb/Q9V9T1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V9T1-1" }, { "uniprot_canonical_ac": "Q9V9U1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V9U1", "url": "https://www.uniprot.org/uniprotkb/Q9V9U1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 591, "chemical_mass": 65056.0, "gene_names": "Smvt;CG2191;Dmel\\CG2191;Dmel_CG2191;SMVT;Smvt;dSLC5A5;smvt", "protein_name": "", "disease": [ { "disease_id": "DOID:0050328", "name": "congenital hypothyroidism", "description": "A hypothyroidism that is present at birth.", "url": "https://disease-ontology.org/term/DOID:0050328", "evidence": [ { "id": "0050328", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050328" } ], "weight": 0.0 }, { "disease_id": "DOID:0112185", "name": "thyroid dyshormonogenesis 1", "description": "A familial thyroid dyshormonogenesis that has_material_basis_in homozygous or compound heterozygous mutation in SLC5A5 on chromosome 19p13.11.", "url": "https://disease-ontology.org/term/DOID:0112185", "evidence": [ { "id": "0112185", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112185" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "D-glucose:sodium symporter activity", "id": "GO:0005412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005412", "evidence": [ { "database": "UniProtKB", "id": "Q9V9U1", "url": "https://www.uniprot.org/uniprotkb/Q9V9U1" } ], "pmid": "" }, { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "Q9V9U1", "url": "https://www.uniprot.org/uniprotkb/Q9V9U1" } ], "pmid": "" } ], "cellular_component": [ { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "Q9V9U1", "url": "https://www.uniprot.org/uniprotkb/Q9V9U1" } ], "pmid": "" } ], "biological_process": [ { "name": "glucose homeostasis", "id": "GO:0042593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042593", "evidence": [ { "database": "UniProtKB", "id": "Q9V9U1", "url": "https://www.uniprot.org/uniprotkb/Q9V9U1" } ], "pmid": "" }, { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "Q9V9U1", "url": "https://www.uniprot.org/uniprotkb/Q9V9U1" } ], "pmid": "" }, { "name": "D-glucose import across plasma membrane", "id": "GO:0098708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098708", "evidence": [ { "database": "UniProtKB", "id": "Q9V9U1", "url": "https://www.uniprot.org/uniprotkb/Q9V9U1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V9U1-1" }, { "uniprot_canonical_ac": "Q9V9W4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V9W4", "url": "https://www.uniprot.org/uniprotkb/Q9V9W4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 472, "chemical_mass": 54034.0, "gene_names": "Dmel\\CG1774;CG1774;Dmel\\CG1774;Dmel_CG1774", "protein_name": "HotDog ACOT-type domain-containing protein", "disease": [], "molecular_function": [ { "name": "acetyl-CoA hydrolase activity", "id": "GO:0003986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003986", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W4", "url": "https://www.uniprot.org/uniprotkb/Q9V9W4" } ], "pmid": "" }, { "name": "fatty acyl-CoA hydrolase activity", "id": "GO:0047617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047617", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W4", "url": "https://www.uniprot.org/uniprotkb/Q9V9W4" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W4", "url": "https://www.uniprot.org/uniprotkb/Q9V9W4" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W4", "url": "https://www.uniprot.org/uniprotkb/Q9V9W4" } ], "pmid": "" } ], "biological_process": [ { "name": "acyl-CoA metabolic process", "id": "GO:0006637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006637", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W4", "url": "https://www.uniprot.org/uniprotkb/Q9V9W4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V9W4-1" }, { "uniprot_canonical_ac": "Q9V9Z3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V9Z3", "url": "https://www.uniprot.org/uniprotkb/Q9V9Z3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 436, "chemical_mass": 48973.0, "gene_names": "qless;CG15565;CG31005;CG3684;Dmel\\CG31005;Dmel_CG31005;Qless;anon-WO0118547.422;qless", "protein_name": "All trans-polyprenyl-diphosphate synthase PDSS1", "disease": [ { "disease_id": "DOID:0070239", "name": "primary coenzyme Q10 deficiency 2", "description": "A primary coenzyme Q10 deficiency that has_material_basis_in an autosomal recessive mutation of the PDSS1 gene on chromosome 10p12.1.", "url": "https://disease-ontology.org/term/DOID:0070239", "evidence": [ { "id": "0070239", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070239" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9V9Z3", "url": "https://www.uniprot.org/uniprotkb/Q9V9Z3" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q9V9Z3", "url": "https://www.uniprot.org/uniprotkb/Q9V9Z3" } ], "pmid": "" }, { "name": "heterotetrameric polyprenyl diphosphate synthase complex", "id": "GO:0032478", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032478", "evidence": [ { "database": "UniProtKB", "id": "Q9V9Z3", "url": "https://www.uniprot.org/uniprotkb/Q9V9Z3" } ], "pmid": "" }, { "name": "polyprenyl diphosphate synthase complex", "id": "GO:0032476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032476", "evidence": [ { "database": "UniProtKB", "id": "Q9V9Z3", "url": "https://www.uniprot.org/uniprotkb/Q9V9Z3" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9V9Z3", "url": "https://www.uniprot.org/uniprotkb/Q9V9Z3" } ], "pmid": "" }, { "name": "prenyltransferase activity", "id": "GO:0004659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004659", "evidence": [ { "database": "UniProtKB", "id": "Q9V9Z3", "url": "https://www.uniprot.org/uniprotkb/Q9V9Z3" } ], "pmid": "" }, { "name": "all-trans-decaprenyl-diphosphate synthase activity", "id": "GO:0097269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097269", "evidence": [ { "database": "UniProtKB", "id": "Q9V9Z3", "url": "https://www.uniprot.org/uniprotkb/Q9V9Z3" } ], "pmid": "" }, { "name": "prenyl diphosphate synthase activity", "id": "GO:0120531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120531", "evidence": [ { "database": "UniProtKB", "id": "Q9V9Z3", "url": "https://www.uniprot.org/uniprotkb/Q9V9Z3" } ], "pmid": "" } ], "biological_process": [ { "name": "ubiquinone biosynthetic process", "id": "GO:0006744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006744", "evidence": [ { "database": "UniProtKB", "id": "Q9V9Z3", "url": "https://www.uniprot.org/uniprotkb/Q9V9Z3" } ], "pmid": "" }, { "name": "isoprenoid biosynthetic process", "id": "GO:0008299", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008299", "evidence": [ { "database": "UniProtKB", "id": "Q9V9Z3", "url": "https://www.uniprot.org/uniprotkb/Q9V9Z3" } ], "pmid": "" }, { "name": "pheromone biosynthetic process", "id": "GO:0042811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042811", "evidence": [ { "database": "UniProtKB", "id": "Q9V9Z3", "url": "https://www.uniprot.org/uniprotkb/Q9V9Z3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V9Z3-1" }, { "uniprot_canonical_ac": "Q9V9Z5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V9Z5", "url": "https://www.uniprot.org/uniprotkb/Q9V9Z5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 116, "chemical_mass": 13388.0, "gene_names": "Dmel\\CG15563;CG15563;Dmel\\CG15563;Dmel_CG15563", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9V9Z5-1" }, { "uniprot_canonical_ac": "Q9VA09-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VA09", "url": "https://www.uniprot.org/uniprotkb/Q9VA09" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 787, "chemical_mass": 86850.0, "gene_names": "Gycbeta100B;CG1470;Dgc beta 1;Dgcbeta1;Dmel\\CG1470;Dmel_CG1470;Gbeta100B;Gyc-beta-100B;Gycbeta-100B;Gycbeta100B;dgcb1;dgcbeta1;gyc beta;gycbeta100B;sGC-beta;sGCbeta100B;sGCbeta1", "protein_name": "Guanylate cyclase soluble subunit beta-1", "disease": [ { "disease_id": "DOID:0060001", "name": "withdrawal disorder", "description": "A substance-related disorder that occurs upon the abrupt discontinuation/separation or a decrease in dosage of the intake of medications, recreational drugs, and alcohol.", "url": "https://disease-ontology.org/term/DOID:0060001", "evidence": [ { "id": "0060001", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060001" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "guanylate cyclase activity", "id": "GO:0004383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004383", "evidence": [ { "database": "UniProtKB", "id": "Q9VA09", "url": "https://www.uniprot.org/uniprotkb/Q9VA09" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q9VA09", "url": "https://www.uniprot.org/uniprotkb/Q9VA09" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VA09", "url": "https://www.uniprot.org/uniprotkb/Q9VA09" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9VA09", "url": "https://www.uniprot.org/uniprotkb/Q9VA09" } ], "pmid": "" } ], "biological_process": [ { "name": "cGMP biosynthetic process", "id": "GO:0006182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006182", "evidence": [ { "database": "UniProtKB", "id": "Q9VA09", "url": "https://www.uniprot.org/uniprotkb/Q9VA09" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "Q9VA09", "url": "https://www.uniprot.org/uniprotkb/Q9VA09" } ], "pmid": "" }, { "name": "response to oxygen levels", "id": "GO:0070482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070482", "evidence": [ { "database": "UniProtKB", "id": "Q9VA09", "url": "https://www.uniprot.org/uniprotkb/Q9VA09" } ], "pmid": "" } ], "cellular_component": [ { "name": "guanylate cyclase complex, soluble", "id": "GO:0008074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008074", "evidence": [ { "database": "UniProtKB", "id": "Q9VA09", "url": "https://www.uniprot.org/uniprotkb/Q9VA09" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VA09-1", "start_pos": "750", "end_pos": "750", "site_lbl": "Thr750", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 750, "start_aa": "Thr", "end_pos": 750, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr750", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VA09-1" }, { "uniprot_canonical_ac": "Q9VA17-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VA17", "url": "https://www.uniprot.org/uniprotkb/Q9VA17" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 529, "chemical_mass": 57069.0, "gene_names": "Sox100B;CG12098;CG15552;CG18674;CT6009;Dmel\\CG15552;Dmel_CG15552;SOX100B;SOXE;Sox100B;Sox100;Sox9;SoxB;dSox9", "protein_name": "", "disease": [ { "disease_id": "DOID:0050463", "name": "campomelic dysplasia", "description": "An osteochondrodysplasia that has_material_basis_in heterozygous mutation in the SOX9 gene on chromosome 17q24 and that is characterized by congenital shortness and bowing of long tubular bones, especially in the lower extremities, as well as by hypoplastic scapulae, narrow iliac wings, and nonmineralized thoracic pedicles.", "url": "https://disease-ontology.org/term/DOID:0050463", "evidence": [ { "id": "0050463", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050463" } ], "weight": 0.0 }, { "disease_id": "DOID:0090111", "name": "PCWH syndrome", "description": "A syndrome that is characterized by the association of the features of Waardenburg-Shah syndrome (sensorineural hearing loss, pigmentary abnormalities and Hirschsprung disease; see this term) with neurological features, including: neonatal hypotonia, intellectual deficit (of variable severity), nystagmus, progressive spasticity, ataxia and epilepsy, and has_material_basis_in heterozygous mutation in the SRY-box 10 (SOX10) gene on chromosome 22q13.", "url": "https://disease-ontology.org/term/DOID:0090111", "evidence": [ { "id": "0090111", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090111" } ], "weight": 0.0 }, { "disease_id": "DOID:0110955", "name": "Waardenburg syndrome type 4C", "description": "A Waardenburg syndrome characterized by pigmentary abnormalities of the hair, skin, and eyes, congenital sensorineural hearing loss, and Hirschsprung disease that has_material_basis_in heterozygous mutation in the SOX10 gene on chromosome 22q13.", "url": "https://disease-ontology.org/term/DOID:0110955", "evidence": [ { "id": "0110955", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110955" } ], "weight": 0.0 }, { "disease_id": "DOID:0110956", "name": "Waardenburg syndrome type 2E", "description": "A Waardenburg syndrome characterized by pigmentary abnormalities of the hair, skin, and eyes, congenital sensorineural hearing loss, and absence of lateral displacement of the inner canthus of each eye that has_material_basis_in heterozygous mutations in the SOX10 gene on chromosome 22q13.", "url": "https://disease-ontology.org/term/DOID:0110956", "evidence": [ { "id": "0110956", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110956" } ], "weight": 0.0 }, { "disease_id": "DOID:0111763", "name": "46,XX sex reversal 2", "description": "A 46,XX sex reversal that has_material_basis_in heterozygous duplication or triplication of a 68-kb regulatory region -584 to -516 kb upstream of the SOX9 gene on chromosome 17q24.", "url": "https://disease-ontology.org/term/DOID:0111763", "evidence": [ { "id": "0111763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111763" } ], "weight": 0.0 }, { "disease_id": "DOID:0111775", "name": "46,XY sex reversal 10", "description": "A 46 XY sex reversal characterized by an XY karyotype, phenotypically female genitalia and failure to develop secondary sexual characteristics at puberty including menstruation that has_material_basis_in heterozygous deletion of a region upstream of the SOX9 gene on chromosome 17q24.", "url": "https://disease-ontology.org/term/DOID:0111775", "evidence": [ { "id": "0111775", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111775" } ], "weight": 0.0 }, { "disease_id": "DOID:10487", "name": "Hirschsprung's disease", "description": "A megacolon that is characterized by a blockage of the large intestine due to improper muscle movement in the bowel.", "url": "https://disease-ontology.org/term/DOID:10487", "evidence": [ { "id": "10487", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10487" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:3614", "name": "Kallmann syndrome", "description": "A hypogonadotropic hypogonadism with a defective sense of smell (anosmia or hyposmia).", "url": "https://disease-ontology.org/term/DOID:3614", "evidence": [ { "id": "3614", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3614" } ], "weight": 0.0 }, { "disease_id": "DOID:3905", "name": "lung carcinoma", "description": "A lung cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells and is located_in the lungs and has_symptom cough and has_symptom chest discomfort or pain and has_symptom weight loss and has_symptom hemoptysis.", "url": "https://disease-ontology.org/term/DOID:3905", "evidence": [ { "id": "3905", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3905" } ], "weight": 0.0 }, { "disease_id": "DOID:9258", "name": "Waardenburg syndrome", "description": "A syndrome characterized by varying degrees of deafness, minor defects in structures arising from the neural crest and pigmentation anomalies of the hair, the skin and/or the iris of both eyes.", "url": "https://disease-ontology.org/term/DOID:9258", "evidence": [ { "id": "9258", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9258" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VA17", "url": "https://www.uniprot.org/uniprotkb/Q9VA17" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VA17", "url": "https://www.uniprot.org/uniprotkb/Q9VA17" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q9VA17", "url": "https://www.uniprot.org/uniprotkb/Q9VA17" } ], "pmid": "" }, { "name": "male gonad development", "id": "GO:0008584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008584", "evidence": [ { "database": "UniProtKB", "id": "Q9VA17", "url": "https://www.uniprot.org/uniprotkb/Q9VA17" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q9VA17", "url": "https://www.uniprot.org/uniprotkb/Q9VA17" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q9VA17", "url": "https://www.uniprot.org/uniprotkb/Q9VA17" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VA17-1" }, { "uniprot_canonical_ac": "Q9VA23-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VA23", "url": "https://www.uniprot.org/uniprotkb/Q9VA23" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 814, "chemical_mass": 94753.0, "gene_names": "Dmel\\CG15548;CG15548;Dmel\\CG15548;Dmel_CG15548", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VA23-1" }, { "uniprot_canonical_ac": "Q9VA48-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VA48", "url": "https://www.uniprot.org/uniprotkb/Q9VA48" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 649, "chemical_mass": 72745.0, "gene_names": "Spn100A;CG1342;Dmel\\CG1342;Dmel_CG1342;Spn100A;Spn100", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VA48", "url": "https://www.uniprot.org/uniprotkb/Q9VA48" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of immune response", "id": "GO:0050776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050776", "evidence": [ { "database": "UniProtKB", "id": "Q9VA48", "url": "https://www.uniprot.org/uniprotkb/Q9VA48" } ], "pmid": "" }, { "name": "mating", "id": "GO:0007618", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007618", "evidence": [ { "database": "UniProtKB", "id": "Q9VA48", "url": "https://www.uniprot.org/uniprotkb/Q9VA48" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VA48-1" }, { "uniprot_canonical_ac": "Q9VA79-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VA79", "url": "https://www.uniprot.org/uniprotkb/Q9VA79" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 486, "chemical_mass": 53744.0, "gene_names": "UIP5;CG2218;Dmel\\CG2218;Dmel_CG2218;UIP5", "protein_name": "U-box domain-containing protein", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VA79", "url": "https://www.uniprot.org/uniprotkb/Q9VA79" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VA79", "url": "https://www.uniprot.org/uniprotkb/Q9VA79" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "Q9VA79", "url": "https://www.uniprot.org/uniprotkb/Q9VA79" } ], "pmid": "" }, { "name": "ubiquitin-ubiquitin ligase activity", "id": "GO:0034450", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034450", "evidence": [ { "database": "UniProtKB", "id": "Q9VA79", "url": "https://www.uniprot.org/uniprotkb/Q9VA79" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "Q9VA79", "url": "https://www.uniprot.org/uniprotkb/Q9VA79" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q9VA79", "url": "https://www.uniprot.org/uniprotkb/Q9VA79" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "Q9VA79", "url": "https://www.uniprot.org/uniprotkb/Q9VA79" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VA79-1" }, { "uniprot_canonical_ac": "Q9VAD4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VAD4", "url": "https://www.uniprot.org/uniprotkb/Q9VAD4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 306, "chemical_mass": 34395.0, "gene_names": "eIF2Balpha;CG7883;DeIF2Balpha;Dmel\\CG7883;Dmel_CG7883;Eif2b;eIF2B-alpha;eIF2Balpha", "protein_name": "Translation initiation factor eIF2B subunit alpha", "disease": [ { "disease_id": "DOID:0060868", "name": "leukoencephalopathy with vanishing white matter", "description": "A leukodystrophy characterized by variable neurologic features resulting from deficiency in astrocyte maturation, including progressive cerebellar ataxia, spasticity, and cognitive impairment associated with white matter lesions on brain imaging with onset from early infancy to adulthood.", "url": "https://disease-ontology.org/term/DOID:0060868", "evidence": [ { "id": "0060868", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060868" } ], "weight": 0.0 }, { "disease_id": "DOID:0070374", "name": "leukoencephalopathy with vanishing white matter 1", "description": "A leukoencephalopathy with vanishing white matter that has_material_basis_in homozygous or compound heterozygous mutation in the EIF2B1 gene on chromosome 12q24.", "url": "https://disease-ontology.org/term/DOID:0070374", "evidence": [ { "id": "0070374", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070374" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VAD4", "url": "https://www.uniprot.org/uniprotkb/Q9VAD4" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 2B complex", "id": "GO:0005851", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005851", "evidence": [ { "database": "UniProtKB", "id": "Q9VAD4", "url": "https://www.uniprot.org/uniprotkb/Q9VAD4" } ], "pmid": "" } ], "biological_process": [ { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "Q9VAD4", "url": "https://www.uniprot.org/uniprotkb/Q9VAD4" } ], "pmid": "" } ], "molecular_function": [ { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "Q9VAD4", "url": "https://www.uniprot.org/uniprotkb/Q9VAD4" } ], "pmid": "" }, { "name": "enzyme regulator activity", "id": "GO:0030234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030234", "evidence": [ { "database": "UniProtKB", "id": "Q9VAD4", "url": "https://www.uniprot.org/uniprotkb/Q9VAD4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VAD4-1", "start_pos": "160", "end_pos": "160", "site_lbl": "Thr160", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 160, "start_aa": "Thr", "end_pos": 160, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr160", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VAD4-1" }, { "uniprot_canonical_ac": "Q9VAF3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VAF3", "url": "https://www.uniprot.org/uniprotkb/Q9VAF3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 352, "chemical_mass": 39981.0, "gene_names": "Dmel\\CG7824;CG7824;Dmel\\CG7824;Dmel_CG7824", "protein_name": "DUF4780 domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VAF3-1" }, { "uniprot_canonical_ac": "Q9VAH7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VAH7", "url": "https://www.uniprot.org/uniprotkb/Q9VAH7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 873, "chemical_mass": 97160.0, "gene_names": "yata;CG1973;Dmel\\CG1973;Dmel_CG1973;Yata;yata", "protein_name": "N-terminal kinase-like protein", "disease": [ { "disease_id": "DOID:0050951", "name": "hereditary ataxia", "description": "A neurodegenerative disease that is characterized by slowly progressive incoordination of gait and often associated with poor coordination of hands, speech, and eye movements.", "url": "https://disease-ontology.org/term/DOID:0050951", "evidence": [ { "id": "0050951", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050951" } ], "weight": 0.0 }, { "disease_id": "DOID:0111155", "name": "autosomal recessive spinocerebellar ataxia 21", "description": "An autosomal recessive cerebellar ataxia that has_material_basis_in homozygous or compound heterozygous mutation in the SCYL1 gene on chromosome 11q13.", "url": "https://disease-ontology.org/term/DOID:0111155", "evidence": [ { "id": "0111155", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111155" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VAH7", "url": "https://www.uniprot.org/uniprotkb/Q9VAH7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VAH7-1" }, { "uniprot_canonical_ac": "Q9VAM5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VAM5", "url": "https://www.uniprot.org/uniprotkb/Q9VAM5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 872, "chemical_mass": 94152.0, "gene_names": "Brd8;Brd8;CG14514;Dmel\\CG14514;dBrd8", "protein_name": "Bromodomain-containing protein 8", "disease": [ { "disease_id": "DOID:0050861", "name": "colorectal adenocarcinoma", "description": "A colorectal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:0050861", "evidence": [ { "id": "0050861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050861" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VAM5", "url": "https://www.uniprot.org/uniprotkb/Q9VAM5" } ], "pmid": "" }, { "name": "NuA4 histone acetyltransferase complex", "id": "GO:0035267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035267", "evidence": [ { "database": "UniProtKB", "id": "Q9VAM5", "url": "https://www.uniprot.org/uniprotkb/Q9VAM5" } ], "pmid": "" } ], "biological_process": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "Q9VAM5", "url": "https://www.uniprot.org/uniprotkb/Q9VAM5" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VAM5", "url": "https://www.uniprot.org/uniprotkb/Q9VAM5" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "Q9VAM5", "url": "https://www.uniprot.org/uniprotkb/Q9VAM5" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "Q9VAM5", "url": "https://www.uniprot.org/uniprotkb/Q9VAM5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VAM5-1", "start_pos": "247", "end_pos": "247", "site_lbl": "Thr247", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 247, "start_aa": "Thr", "end_pos": 247, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr247", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VAM5-1" }, { "uniprot_canonical_ac": "Q9VAN7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VAN7", "url": "https://www.uniprot.org/uniprotkb/Q9VAN7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 255, "chemical_mass": 28573.0, "gene_names": "Pgam1;CG1721;Dmel\\CG1721;Dmel_CG1721;PGAM;PGLYM;Pglym78;Pglym;pglym78", "protein_name": "Phosphoglycerate mutase", "disease": [ { "disease_id": "DOID:0080108", "name": "myoglobinuria", "description": "A myopathy that is characterized by an increased urinary excretion of myoglobin.", "url": "https://disease-ontology.org/term/DOID:0080108", "evidence": [ { "id": "0080108", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080108" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "bisphosphoglycerate mutase activity", "id": "GO:0004082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004082", "evidence": [ { "database": "UniProtKB", "id": "Q9VAN7", "url": "https://www.uniprot.org/uniprotkb/Q9VAN7" } ], "pmid": "" }, { "name": "phosphoglycerate mutase activity", "id": "GO:0004619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004619", "evidence": [ { "database": "UniProtKB", "id": "Q9VAN7", "url": "https://www.uniprot.org/uniprotkb/Q9VAN7" } ], "pmid": "" }, { "name": "phosphatase activity", "id": "GO:0016791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016791", "evidence": [ { "database": "UniProtKB", "id": "Q9VAN7", "url": "https://www.uniprot.org/uniprotkb/Q9VAN7" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VAN7", "url": "https://www.uniprot.org/uniprotkb/Q9VAN7" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "Q9VAN7", "url": "https://www.uniprot.org/uniprotkb/Q9VAN7" } ], "pmid": "" }, { "name": "M band", "id": "GO:0031430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031430", "evidence": [ { "database": "UniProtKB", "id": "Q9VAN7", "url": "https://www.uniprot.org/uniprotkb/Q9VAN7" } ], "pmid": "" } ], "biological_process": [ { "name": "gluconeogenesis", "id": "GO:0006094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006094", "evidence": [ { "database": "UniProtKB", "id": "Q9VAN7", "url": "https://www.uniprot.org/uniprotkb/Q9VAN7" } ], "pmid": "" }, { "name": "canonical glycolysis", "id": "GO:0061621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061621", "evidence": [ { "database": "UniProtKB", "id": "Q9VAN7", "url": "https://www.uniprot.org/uniprotkb/Q9VAN7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VAN7-1" }, { "uniprot_canonical_ac": "Q9VAR2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VAR2", "url": "https://www.uniprot.org/uniprotkb/Q9VAR2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 179, "chemical_mass": 20952.0, "gene_names": "Dmel\\CG14518;CG14518;Dmel\\CG14518;Dmel_CG14518", "protein_name": "MD-2-related lipid-recognition domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VAR2-1" }, { "uniprot_canonical_ac": "Q9VAS2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VAS2", "url": "https://www.uniprot.org/uniprotkb/Q9VAS2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 682, "chemical_mass": 78936.0, "gene_names": "Nepl18;CG14528;Dmel\\CG14528;Dmel_CG14528;Nepl18", "protein_name": "", "disease": [ { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:13250", "name": "diarrhea", "description": "A gastrointestinal system disease described as the condition of having frequent loose or liquid bowel movements. Acute diarrhea is a common cause of death in developing countries and the second most common cause of infant deaths worldwide. The loss of fluids through diarrhea can cause severe dehydration which is one cause of death in diarrhea sufferers. Along with water, sufferers also lose dangerous amounts of important salts, electrolytes, and other nutrients. There are at least four types of diarrhea: secretory diarrhea, osmotic diarrhea, motility-related diarrhea, and inflammatory diarrhea.", "url": "https://disease-ontology.org/term/DOID:13250", "evidence": [ { "id": "13250", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13250" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VAS2", "url": "https://www.uniprot.org/uniprotkb/Q9VAS2" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VAS2", "url": "https://www.uniprot.org/uniprotkb/Q9VAS2" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q9VAS2", "url": "https://www.uniprot.org/uniprotkb/Q9VAS2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VAS2", "url": "https://www.uniprot.org/uniprotkb/Q9VAS2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VAS2-1" }, { "uniprot_canonical_ac": "Q9VAU5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VAU5", "url": "https://www.uniprot.org/uniprotkb/Q9VAU5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2119, "chemical_mass": 233066.0, "gene_names": "Dmel\\CG10011;CG10011;Dmel\\CG10011;Dmel_CG10011", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VAU5-1", "start_pos": "1995", "end_pos": "1995", "site_lbl": "Thr1995", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1995, "start_aa": "Thr", "end_pos": 1995, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1995", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VAU5-1" }, { "uniprot_canonical_ac": "Q9VAY0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VAY0", "url": "https://www.uniprot.org/uniprotkb/Q9VAY0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 717, "chemical_mass": 82103.0, "gene_names": "Nep7;CG5527;Dmel\\CG5527;Dmel_CG5527;Nep7", "protein_name": "", "disease": [ { "disease_id": "DOID:0050646", "name": "distal arthrogryposis", "description": "A muscle tissue disease characterized by congenital joint contractures of hand and feet.", "url": "https://disease-ontology.org/term/DOID:0050646", "evidence": [ { "id": "0050646", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050646" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:13250", "name": "diarrhea", "description": "A gastrointestinal system disease described as the condition of having frequent loose or liquid bowel movements. Acute diarrhea is a common cause of death in developing countries and the second most common cause of infant deaths worldwide. The loss of fluids through diarrhea can cause severe dehydration which is one cause of death in diarrhea sufferers. Along with water, sufferers also lose dangerous amounts of important salts, electrolytes, and other nutrients. There are at least four types of diarrhea: secretory diarrhea, osmotic diarrhea, motility-related diarrhea, and inflammatory diarrhea.", "url": "https://disease-ontology.org/term/DOID:13250", "evidence": [ { "id": "13250", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13250" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "Q9VAY0", "url": "https://www.uniprot.org/uniprotkb/Q9VAY0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VAY0", "url": "https://www.uniprot.org/uniprotkb/Q9VAY0" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VAY0", "url": "https://www.uniprot.org/uniprotkb/Q9VAY0" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VAY0", "url": "https://www.uniprot.org/uniprotkb/Q9VAY0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VAY0-1" }, { "uniprot_canonical_ac": "Q9VB45-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VB45", "url": "https://www.uniprot.org/uniprotkb/Q9VB45" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 98, "chemical_mass": 11343.0, "gene_names": "Dmel\\CG3348;CG3348;Dmel\\CG3348;Dmel_CG3348", "protein_name": "Chitin-binding type-2 domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VB45", "url": "https://www.uniprot.org/uniprotkb/Q9VB45" } ], "pmid": "" } ], "molecular_function": [ { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "Q9VB45", "url": "https://www.uniprot.org/uniprotkb/Q9VB45" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VB45-1" }, { "uniprot_canonical_ac": "Q9VB48-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VB48", "url": "https://www.uniprot.org/uniprotkb/Q9VB48" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1120, "chemical_mass": 127262.0, "gene_names": "SD09067p;CG3368;Dmel\\CG3368;Dmel_CG3368;SD09067p", "protein_name": "DUF2428 domain-containing protein", "disease": [], "biological_process": [ { "name": "tRNA nucleoside ribose methylation", "id": "GO:0002128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002128", "evidence": [ { "database": "UniProtKB", "id": "Q9VB48", "url": "https://www.uniprot.org/uniprotkb/Q9VB48" } ], "pmid": "" } ], "molecular_function": [ { "name": "enzyme regulator activity", "id": "GO:0030234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030234", "evidence": [ { "database": "UniProtKB", "id": "Q9VB48", "url": "https://www.uniprot.org/uniprotkb/Q9VB48" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VB48-1" }, { "uniprot_canonical_ac": "Q9VB54-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VB54", "url": "https://www.uniprot.org/uniprotkb/Q9VB54" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 312, "chemical_mass": 35199.0, "gene_names": "Dmel\\CG14262;CG14262;Dmel\\CG14262;Dmel_CG14262", "protein_name": "BTB domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VB54-1" }, { "uniprot_canonical_ac": "Q9VB71-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VB71", "url": "https://www.uniprot.org/uniprotkb/Q9VB71" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 884, "chemical_mass": 104078.0, "gene_names": "Dmel\\CG6059;CG6059;Dmel\\CG6059;Dmel_CG6059", "protein_name": "Cilia- and flagella-associated protein 58 central coiled coil domain-containing protein", "disease": [ { "disease_id": "DOID:0070311", "name": "oligoasthenoteratozoospermia", "description": "A form of male infertility that is characterized by a combination of low number or oligozoospermia, poor motility or asthenozoospermia, and abnormal shape or teratozoospermia of sperms. OAT is the most common cause of male subfertility.", "url": "https://disease-ontology.org/term/DOID:0070311", "evidence": [ { "id": "0070311", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070311" } ], "weight": 0.0 }, { "disease_id": "DOID:0112271", "name": "spermatogenic failure 49", "description": "A spermatogenic failure characterized by multiple morphologic abnormalities of the sperm flagella resulting in markedly reduced or no progressive motility that has_material_basis_in homozygous or compound heterozygous mutation in the CFAP58 gene on chromosome 10q25.1.", "url": "https://disease-ontology.org/term/DOID:0112271", "evidence": [ { "id": "0112271", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112271" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "Q9VB71", "url": "https://www.uniprot.org/uniprotkb/Q9VB71" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VB71-1" }, { "uniprot_canonical_ac": "Q9VB76-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VB76", "url": "https://www.uniprot.org/uniprotkb/Q9VB76" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 311, "chemical_mass": 35053.0, "gene_names": "CAH9;CAH9;CAIX;CG6074;CT19053;Dmel\\CG6074;Dmel_CG6074;caix", "protein_name": "Carbonic anhydrase", "disease": [ { "disease_id": "DOID:0050861", "name": "colorectal adenocarcinoma", "description": "A colorectal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:0050861", "evidence": [ { "id": "0050861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050861" } ], "weight": 0.0 }, { "disease_id": "DOID:0050997", "name": "cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome", "description": "A syndrome characterized by congenital onset of nonprogressive cerebellar ataxia, disturbed equilibrium, and mental retardation, associated with cerebellar hypoplasia.", "url": "https://disease-ontology.org/term/DOID:0050997", "evidence": [ { "id": "0050997", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050997" } ], "weight": 0.0 }, { "disease_id": "DOID:0080199", "name": "colorectal carcinoma", "description": "A colorectal cancer that arises from the colon or rectum and invades through the muscularis mucosa into the submucosa.", "url": "https://disease-ontology.org/term/DOID:0080199", "evidence": [ { "id": "0080199", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080199" } ], "weight": 0.0 }, { "disease_id": "DOID:0080365", "name": "endometrial hyperplasia", "description": "An uterine benign neoplasm that is characterized by excessive proliferation of the cells of the endometrium.", "url": "https://disease-ontology.org/term/DOID:0080365", "evidence": [ { "id": "0080365", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080365" } ], "weight": 0.0 }, { "disease_id": "DOID:0111371", "name": "isolated hyperchlorhidrosis", "description": "A skin disease characterized by excessive loss of salt in sweat resulting in low levels of salt in the blood in the absence of other symptoms that has_material_basis_in homozygous or compound heterozygous mutation in the CA12 gene on chromosome 15q22.2.", "url": "https://disease-ontology.org/term/DOID:0111371", "evidence": [ { "id": "0111371", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111371" } ], "weight": 0.0 }, { "disease_id": "DOID:10584", "name": "retinitis pigmentosa", "description": "A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.", "url": "https://disease-ontology.org/term/DOID:10584", "evidence": [ { "id": "10584", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10584" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:2043", "name": "hepatitis B", "description": "A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in Hepatitis B virus (Orthohepadnavirus hominoidei), which is transmitted_by sexual contact, blood transfusions, or fomites like needles or syringes. The infection has_symptom fever, fatigue, loss of appetite, nausea, vomiting, abdominal pain, clay-colored bowel movements, joint pain, and jaundice.", "url": "https://disease-ontology.org/term/DOID:2043", "evidence": [ { "id": "2043", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2043" } ], "weight": 0.0 }, { "disease_id": "DOID:234", "name": "colon adenocarcinoma", "description": "A colon carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:234", "evidence": [ { "id": "234", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:234" } ], "weight": 0.0 }, { "disease_id": "DOID:2671", "name": "transitional cell carcinoma", "description": "A carcinoma that derives_from transitional epithelial cells.", "url": "https://disease-ontology.org/term/DOID:2671", "evidence": [ { "id": "2671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2671" } ], "weight": 0.0 }, { "disease_id": "DOID:3459", "name": "breast carcinoma", "description": "A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:3459", "evidence": [ { "id": "3459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3459" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:3883", "name": "Lynch syndrome", "description": "A syndrome that is characterized by an increased risk for colon cancer and cancers of the endometrium, ovary, stomach, small intestine, hepatobiliary tract, urinary tract, brain, and skin and has_material_basis_in mutation of mismatch repair genes that increases the risk of many types of cancers.", "url": "https://disease-ontology.org/term/DOID:3883", "evidence": [ { "id": "3883", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3883" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:5015", "name": "fibrolamellar carcinoma", "description": "A hepatocellular carcinoma characterized microscopically by laminated fibrous layers interspersed between the tumour cells. The polygonal, deeply eosinophilic tumor cells arise in non-cirrhotic livers.", "url": "https://disease-ontology.org/term/DOID:5015", "evidence": [ { "id": "5015", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5015" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VB76", "url": "https://www.uniprot.org/uniprotkb/Q9VB76" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VB76", "url": "https://www.uniprot.org/uniprotkb/Q9VB76" } ], "pmid": "" }, { "name": "carbonate dehydratase activity", "id": "GO:0004089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004089", "evidence": [ { "database": "UniProtKB", "id": "Q9VB76", "url": "https://www.uniprot.org/uniprotkb/Q9VB76" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VB76-1" }, { "uniprot_canonical_ac": "Q9VB80-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VB80", "url": "https://www.uniprot.org/uniprotkb/Q9VB80" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 258, "chemical_mass": 29156.0, "gene_names": "Dmel\\CG14258;CG14258;Dmel\\CG14258;Dmel_CG14258", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VB80", "url": "https://www.uniprot.org/uniprotkb/Q9VB80" } ], "pmid": "" } ], "biological_process": [ { "name": "circadian rhythm", "id": "GO:0007623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007623", "evidence": [ { "database": "UniProtKB", "id": "Q9VB80", "url": "https://www.uniprot.org/uniprotkb/Q9VB80" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VB80-1" }, { "uniprot_canonical_ac": "Q9VB89-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VB89", "url": "https://www.uniprot.org/uniprotkb/Q9VB89" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 341, "chemical_mass": 37167.0, "gene_names": "DmelL2;CG6277;DmelL2;Dmel\\CG6277;Dmel_CG6277", "protein_name": "Lipase domain-containing protein", "disease": [ { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VB89", "url": "https://www.uniprot.org/uniprotkb/Q9VB89" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipase activity", "id": "GO:0016298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016298", "evidence": [ { "database": "UniProtKB", "id": "Q9VB89", "url": "https://www.uniprot.org/uniprotkb/Q9VB89" } ], "pmid": "" }, { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "Q9VB89", "url": "https://www.uniprot.org/uniprotkb/Q9VB89" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "Q9VB89", "url": "https://www.uniprot.org/uniprotkb/Q9VB89" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VB89-1" }, { "uniprot_canonical_ac": "Q9VB95-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VB95", "url": "https://www.uniprot.org/uniprotkb/Q9VB95" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 360, "chemical_mass": 39484.0, "gene_names": "TwdlC;CG14254;Dmel\\CG14254;Dmel_CG14254;TwdlC", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "Q9VB95", "url": "https://www.uniprot.org/uniprotkb/Q9VB95" } ], "pmid": "" }, { "name": "chitin-based extracellular matrix", "id": "GO:0062129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062129", "evidence": [ { "database": "UniProtKB", "id": "Q9VB95", "url": "https://www.uniprot.org/uniprotkb/Q9VB95" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of chitin-based cuticle", "id": "GO:0005214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005214", "evidence": [ { "database": "UniProtKB", "id": "Q9VB95", "url": "https://www.uniprot.org/uniprotkb/Q9VB95" } ], "pmid": "" }, { "name": "structural constituent of chitin-based larval cuticle", "id": "GO:0008010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008010", "evidence": [ { "database": "UniProtKB", "id": "Q9VB95", "url": "https://www.uniprot.org/uniprotkb/Q9VB95" } ], "pmid": "" } ], "biological_process": [ { "name": "chitin-based cuticle development", "id": "GO:0040003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040003", "evidence": [ { "database": "UniProtKB", "id": "Q9VB95", "url": "https://www.uniprot.org/uniprotkb/Q9VB95" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VB95-1", "start_pos": "89", "end_pos": "89", "site_lbl": "Thr89", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 89, "start_aa": "Thr", "end_pos": 89, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr89", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VB95-1" }, { "uniprot_canonical_ac": "Q9VBA1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBA1", "url": "https://www.uniprot.org/uniprotkb/Q9VBA1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 469, "chemical_mass": 53825.0, "gene_names": "Spag1;CG18472;Dmel\\CG18472;Dmel_CG18472;Spag1", "protein_name": "", "disease": [ { "disease_id": "DOID:0110607", "name": "primary ciliary dyskinesia 28", "description": "A primary ciliary dyskinesia that is characterized by autosomal recessive inheritance with outer and inner dynein arm defect, recurrent upper and lower airway disease, bronchiectasis, and decreased fertility and has_material_basis_in homozygous or compound heterozygous mutation in the SPAG1 gene on chromosome 8q22.", "url": "https://disease-ontology.org/term/DOID:0110607", "evidence": [ { "id": "0110607", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110607" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VBA1", "url": "https://www.uniprot.org/uniprotkb/Q9VBA1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VBA1", "url": "https://www.uniprot.org/uniprotkb/Q9VBA1" } ], "pmid": "" }, { "name": "protein folding chaperone complex", "id": "GO:0101031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0101031", "evidence": [ { "database": "UniProtKB", "id": "Q9VBA1", "url": "https://www.uniprot.org/uniprotkb/Q9VBA1" } ], "pmid": "" } ], "molecular_function": [ { "name": "heat shock protein binding", "id": "GO:0031072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031072", "evidence": [ { "database": "UniProtKB", "id": "Q9VBA1", "url": "https://www.uniprot.org/uniprotkb/Q9VBA1" } ], "pmid": "" } ], "biological_process": [ { "name": "protein targeting to mitochondrion", "id": "GO:0006626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006626", "evidence": [ { "database": "UniProtKB", "id": "Q9VBA1", "url": "https://www.uniprot.org/uniprotkb/Q9VBA1" } ], "pmid": "" }, { "name": "axonemal dynein complex assembly", "id": "GO:0070286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070286", "evidence": [ { "database": "UniProtKB", "id": "Q9VBA1", "url": "https://www.uniprot.org/uniprotkb/Q9VBA1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VBA1-1" }, { "uniprot_canonical_ac": "Q9VBA2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBA2", "url": "https://www.uniprot.org/uniprotkb/Q9VBA2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 405, "chemical_mass": 47215.0, "gene_names": "Dmel\\CG14252;CG14252;Dmel\\CG14252;Dmel_CG14252", "protein_name": "Myb/SANT-like DNA-binding domain-containing protein", "disease": [], "cellular_component": [ { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "Q9VBA2", "url": "https://www.uniprot.org/uniprotkb/Q9VBA2" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "Q9VBA2", "url": "https://www.uniprot.org/uniprotkb/Q9VBA2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VBA2-1" }, { "uniprot_canonical_ac": "Q9VBD5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBD5", "url": "https://www.uniprot.org/uniprotkb/Q9VBD5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 309, "chemical_mass": 30854.0, "gene_names": "TwdlN;BcDNA:RE20092;BcDNA:RE59605;CG5476;Dmel\\CG5476;Dmel_CG5476;TwdlN;chr3R:22457526..22457631", "protein_name": "", "disease": [], "biological_process": [ { "name": "body morphogenesis", "id": "GO:0010171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010171", "evidence": [ { "database": "UniProtKB", "id": "Q9VBD5", "url": "https://www.uniprot.org/uniprotkb/Q9VBD5" } ], "pmid": "" }, { "name": "chitin-based cuticle development", "id": "GO:0040003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040003", "evidence": [ { "database": "UniProtKB", "id": "Q9VBD5", "url": "https://www.uniprot.org/uniprotkb/Q9VBD5" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "Q9VBD5", "url": "https://www.uniprot.org/uniprotkb/Q9VBD5" } ], "pmid": "" }, { "name": "chitin-based extracellular matrix", "id": "GO:0062129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062129", "evidence": [ { "database": "UniProtKB", "id": "Q9VBD5", "url": "https://www.uniprot.org/uniprotkb/Q9VBD5" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of chitin-based cuticle", "id": "GO:0005214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005214", "evidence": [ { "database": "UniProtKB", "id": "Q9VBD5", "url": "https://www.uniprot.org/uniprotkb/Q9VBD5" } ], "pmid": "" }, { "name": "structural constituent of chitin-based larval cuticle", "id": "GO:0008010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008010", "evidence": [ { "database": "UniProtKB", "id": "Q9VBD5", "url": "https://www.uniprot.org/uniprotkb/Q9VBD5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VBD5-1" }, { "uniprot_canonical_ac": "Q9VBD7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBD7", "url": "https://www.uniprot.org/uniprotkb/Q9VBD7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 247, "chemical_mass": 25909.0, "gene_names": "TwdlK;CG6460;Dmel\\CG6460;Dmel_CG6460;TwdlK", "protein_name": "", "disease": [], "biological_process": [ { "name": "body morphogenesis", "id": "GO:0010171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010171", "evidence": [ { "database": "UniProtKB", "id": "Q9VBD7", "url": "https://www.uniprot.org/uniprotkb/Q9VBD7" } ], "pmid": "" }, { "name": "chitin-based cuticle development", "id": "GO:0040003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040003", "evidence": [ { "database": "UniProtKB", "id": "Q9VBD7", "url": "https://www.uniprot.org/uniprotkb/Q9VBD7" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "Q9VBD7", "url": "https://www.uniprot.org/uniprotkb/Q9VBD7" } ], "pmid": "" }, { "name": "chitin-based extracellular matrix", "id": "GO:0062129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062129", "evidence": [ { "database": "UniProtKB", "id": "Q9VBD7", "url": "https://www.uniprot.org/uniprotkb/Q9VBD7" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of chitin-based cuticle", "id": "GO:0005214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005214", "evidence": [ { "database": "UniProtKB", "id": "Q9VBD7", "url": "https://www.uniprot.org/uniprotkb/Q9VBD7" } ], "pmid": "" }, { "name": "structural constituent of chitin-based larval cuticle", "id": "GO:0008010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008010", "evidence": [ { "database": "UniProtKB", "id": "Q9VBD7", "url": "https://www.uniprot.org/uniprotkb/Q9VBD7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VBD7-1" }, { "uniprot_canonical_ac": "Q9VBE1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBE1", "url": "https://www.uniprot.org/uniprotkb/Q9VBE1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 220, "chemical_mass": 23503.0, "gene_names": "TwdlP;CG14240;Dmel\\CG14240;Dmel_CG14240;TwdlP", "protein_name": "", "disease": [], "biological_process": [ { "name": "body morphogenesis", "id": "GO:0010171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010171", "evidence": [ { "database": "UniProtKB", "id": "Q9VBE1", "url": "https://www.uniprot.org/uniprotkb/Q9VBE1" } ], "pmid": "" }, { "name": "chitin-based cuticle development", "id": "GO:0040003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040003", "evidence": [ { "database": "UniProtKB", "id": "Q9VBE1", "url": "https://www.uniprot.org/uniprotkb/Q9VBE1" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "Q9VBE1", "url": "https://www.uniprot.org/uniprotkb/Q9VBE1" } ], "pmid": "" }, { "name": "chitin-based extracellular matrix", "id": "GO:0062129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062129", "evidence": [ { "database": "UniProtKB", "id": "Q9VBE1", "url": "https://www.uniprot.org/uniprotkb/Q9VBE1" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of chitin-based cuticle", "id": "GO:0005214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005214", "evidence": [ { "database": "UniProtKB", "id": "Q9VBE1", "url": "https://www.uniprot.org/uniprotkb/Q9VBE1" } ], "pmid": "" }, { "name": "structural constituent of chitin-based larval cuticle", "id": "GO:0008010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008010", "evidence": [ { "database": "UniProtKB", "id": "Q9VBE1", "url": "https://www.uniprot.org/uniprotkb/Q9VBE1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VBE1-1" }, { "uniprot_canonical_ac": "Q9VBE5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBE5", "url": "https://www.uniprot.org/uniprotkb/Q9VBE5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1298, "chemical_mass": 143460.0, "gene_names": "plum;CG6490;CT20213;Dmel\\CG6490;Dmel_CG6490;Plum;plum", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VBE5", "url": "https://www.uniprot.org/uniprotkb/Q9VBE5" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "Q9VBE5", "url": "https://www.uniprot.org/uniprotkb/Q9VBE5" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "Q9VBE5", "url": "https://www.uniprot.org/uniprotkb/Q9VBE5" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q9VBE5", "url": "https://www.uniprot.org/uniprotkb/Q9VBE5" } ], "pmid": "" } ], "biological_process": [ { "name": "neuron remodeling", "id": "GO:0016322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016322", "evidence": [ { "database": "UniProtKB", "id": "Q9VBE5", "url": "https://www.uniprot.org/uniprotkb/Q9VBE5" } ], "pmid": "" }, { "name": "neuron projection morphogenesis", "id": "GO:0048812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048812", "evidence": [ { "database": "UniProtKB", "id": "Q9VBE5", "url": "https://www.uniprot.org/uniprotkb/Q9VBE5" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "Q9VBE5", "url": "https://www.uniprot.org/uniprotkb/Q9VBE5" } ], "pmid": "" }, { "name": "negative regulation of synaptic assembly at neuromuscular junction", "id": "GO:0045886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045886", "evidence": [ { "database": "UniProtKB", "id": "Q9VBE5", "url": "https://www.uniprot.org/uniprotkb/Q9VBE5" } ], "pmid": "" } ], "molecular_function": [ { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "Q9VBE5", "url": "https://www.uniprot.org/uniprotkb/Q9VBE5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VBE5-1", "start_pos": "1061", "end_pos": "1061", "site_lbl": "Thr1061", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1061, "start_aa": "Thr", "end_pos": 1061, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1061", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VBE5-1" }, { "uniprot_canonical_ac": "Q9VBH0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBH0", "url": "https://www.uniprot.org/uniprotkb/Q9VBH0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 334, "chemical_mass": 38602.0, "gene_names": "Dmel\\CG14556;CG14556;Dmel\\CG14556;Dmel_CG14556", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VBH0-1" }, { "uniprot_canonical_ac": "Q9VBK6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBK6", "url": "https://www.uniprot.org/uniprotkb/Q9VBK6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 421, "chemical_mass": 47648.0, "gene_names": "CG5990;CG31089;CG5990;Dmel\\CG31089;Dmel_CG31089", "protein_name": "Lipase", "disease": [ { "disease_id": "DOID:0060717", "name": "autosomal recessive congenital ichthyosis 8", "description": "An autosomal recessive congenital ichthyosis characterized by diffuse lamellar ichthyosis, slight facial erythema, hyperkeratosis, orthokeratosis, hypergranulosis, and acanthosis that has_material_basis_in homozygous mutation in the LIPN gene on chromosome 10q23.", "url": "https://disease-ontology.org/term/DOID:0060717", "evidence": [ { "id": "0060717", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060717" } ], "weight": 0.0 }, { "disease_id": "DOID:0080217", "name": "lysosomal acid lipase deficiency", "description": "A lipid storage disease characterized by dyslipidemia and accumulation of cholesteryl esters and triglycerides within various organs that has_material_basis_in homozygous or compound heterozygous mutation in the LIPA gene on chromosome 10q23.31.", "url": "https://disease-ontology.org/term/DOID:0080217", "evidence": [ { "id": "0080217", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080217" } ], "weight": 0.0 }, { "disease_id": "DOID:14497", "name": "Wolman disease", "description": "A lysosomal acid lipase deficiency characterized by infantile onset of rapidly progressive accumulation of cholesteryl esters and triglycerides throughout the body, resulting in hepatosplenomegaly, severe malnutrition, jaundice, vomiting, diarrhea, steatorrhea. Death usually occurs within the first year of life.", "url": "https://disease-ontology.org/term/DOID:14497", "evidence": [ { "id": "14497", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14497" } ], "weight": 0.0 }, { "disease_id": "DOID:14502", "name": "cholesterol ester storage disease", "description": "A lysosomal acid lipase deficiency characterized by onset in childhood or later of progressive accumulation of cholesteryl esters and triglycerides primarily in the liver and spleen.", "url": "https://disease-ontology.org/term/DOID:14502", "evidence": [ { "id": "14502", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14502" } ], "weight": 0.0 } ], "biological_process": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "Q9VBK6", "url": "https://www.uniprot.org/uniprotkb/Q9VBK6" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "Q9VBK6", "url": "https://www.uniprot.org/uniprotkb/Q9VBK6" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipase activity", "id": "GO:0016298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016298", "evidence": [ { "database": "UniProtKB", "id": "Q9VBK6", "url": "https://www.uniprot.org/uniprotkb/Q9VBK6" } ], "pmid": "" }, { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "Q9VBK6", "url": "https://www.uniprot.org/uniprotkb/Q9VBK6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VBK6-1", "start_pos": "225", "end_pos": "225", "site_lbl": "Ser225", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 225, "start_aa": "Ser", "end_pos": 225, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser225", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VBK6", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VBK6" } ] } ] } ], "record_id": "Q9VBK6-1" }, { "uniprot_canonical_ac": "Q9VBM3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBM3", "url": "https://www.uniprot.org/uniprotkb/Q9VBM3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 174, "chemical_mass": 20235.0, "gene_names": "BcDNA:AT31258;BcDNA:AT31258;CG4960;Dmel\\CG4960;Dmel_CG4960", "protein_name": "Receptor expression-enhancing protein", "disease": [ { "disease_id": "DOID:0080350", "name": "retinitis pigmentosa 77", "description": "A retinitis pigmentosa that has_material_basis_in mutation in the REEP6 gene on chromosome 19p13.", "url": "https://disease-ontology.org/term/DOID:0080350", "evidence": [ { "id": "0080350", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080350" } ], "weight": 0.0 }, { "disease_id": "DOID:0110782", "name": "hereditary spastic paraplegia 31", "description": "A hereditary spastic paraplegia that has_material_basis_in mutation in the REEP1 gene on chromosome 2p11.", "url": "https://disease-ontology.org/term/DOID:0110782", "evidence": [ { "id": "0110782", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110782" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VBM3", "url": "https://www.uniprot.org/uniprotkb/Q9VBM3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VBM3-1" }, { "uniprot_canonical_ac": "Q9VBM5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBM5", "url": "https://www.uniprot.org/uniprotkb/Q9VBM5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 283, "chemical_mass": 33147.0, "gene_names": "CG17195-PA;CG17195-PA;CG17195;Dmel\\CG17195;Dmel_CG17195", "protein_name": "Palmitoyltransferase", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q9VBM5", "url": "https://www.uniprot.org/uniprotkb/Q9VBM5" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q9VBM5", "url": "https://www.uniprot.org/uniprotkb/Q9VBM5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VBM5", "url": "https://www.uniprot.org/uniprotkb/Q9VBM5" } ], "pmid": "" } ], "biological_process": [ { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "Q9VBM5", "url": "https://www.uniprot.org/uniprotkb/Q9VBM5" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "Q9VBM5", "url": "https://www.uniprot.org/uniprotkb/Q9VBM5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VBM5-1" }, { "uniprot_canonical_ac": "Q9VBN5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBN5", "url": "https://www.uniprot.org/uniprotkb/Q9VBN5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 135, "chemical_mass": 15903.0, "gene_names": "RpL27;CG4759;Dmel\\CG4759;Dmel_CG4759;L27e;RPL27;RpL27e;RpL27;chr3R:21510055..21510241", "protein_name": "60S ribosomal protein L27", "disease": [ { "disease_id": "DOID:0111893", "name": "Diamond-Blackfan anemia 16", "description": "A Diamond-Blackfan anemia that has_material_basis_in heterozygous mutation in the RPL27 gene on chromosome 17q21.31.", "url": "https://disease-ontology.org/term/DOID:0111893", "evidence": [ { "id": "0111893", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111893" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosolic ribosome", "id": "GO:0022626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022626", "evidence": [ { "database": "UniProtKB", "id": "Q9VBN5", "url": "https://www.uniprot.org/uniprotkb/Q9VBN5" } ], "pmid": "" }, { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "Q9VBN5", "url": "https://www.uniprot.org/uniprotkb/Q9VBN5" } ], "pmid": "" } ], "biological_process": [ { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "Q9VBN5", "url": "https://www.uniprot.org/uniprotkb/Q9VBN5" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "Q9VBN5", "url": "https://www.uniprot.org/uniprotkb/Q9VBN5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VBN5-1" }, { "uniprot_canonical_ac": "Q9VBR1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBR1", "url": "https://www.uniprot.org/uniprotkb/Q9VBR1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 640, "chemical_mass": 71214.0, "gene_names": "Vps33B;CG5127;Dmel\\CG5127;Dmel_CG5127;VPS33B;VPS33b;Vps 33B;Vps33B;Vps33b;dVps33B", "protein_name": "", "disease": [ { "disease_id": "DOID:0050763", "name": "ARC syndrome", "description": "A syndrome that is characterized by congenital joint contractures, renal tubular dysfunction, cholestasis, severe failure to thrive, ichthyosis and a defect in platelet alpha-granule biogenesis and that has_material_basis_in homozygous or compound heterozygous mutation in the VPS33B gene or homozygous or compound heterozygous mutation in the VIPAR gene on chromosome 14q24.3.", "url": "https://disease-ontology.org/term/DOID:0050763", "evidence": [ { "id": "0050763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050763" } ], "weight": 0.0 }, { "disease_id": "DOID:0070221", "name": "progressive familial intrahepatic cholestasis", "description": "An intrahepatic cholestasis characterized by early onset of chronic unremitting cholestasis of hepatocellular origin that progresses to hepatic fibrosis, cirrhosis, and end-stage liver disease before adulthood.", "url": "https://disease-ontology.org/term/DOID:0070221", "evidence": [ { "id": "0070221", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070221" } ], "weight": 0.0 }, { "disease_id": "DOID:0080954", "name": "arthrogryposis multiplex congenita", "description": "A nervous system disease that is characterized by development of multiple joint contractures affecting two or more areas of the body prior to birth.", "url": "https://disease-ontology.org/term/DOID:0080954", "evidence": [ { "id": "0080954", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080954" } ], "weight": 0.0 }, { "disease_id": "DOID:0111353", "name": "arthrogryposis, renal dysfunction, and cholestasis 1", "description": "An arthrogryposis, renal dysfunction, and cholestasis that has_material_basis_in homozygous or compound heterozygous mutation in VPS33B on 15q26.1.", "url": "https://disease-ontology.org/term/DOID:0111353", "evidence": [ { "id": "0111353", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111353" } ], "weight": 0.0 }, { "disease_id": "DOID:13580", "name": "cholestasis", "description": "A bile duct disease that is characterized by where bile cannot flow from the liver to the duodenum.", "url": "https://disease-ontology.org/term/DOID:13580", "evidence": [ { "id": "13580", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13580" } ], "weight": 0.0 }, { "disease_id": "DOID:557", "name": "kidney disease", "description": "A urinary system disease that is located_in the kidney.", "url": "https://disease-ontology.org/term/DOID:557", "evidence": [ { "id": "557", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:557" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of SNARE complex assembly", "id": "GO:0035542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035542", "evidence": [ { "database": "UniProtKB", "id": "Q9VBR1", "url": "https://www.uniprot.org/uniprotkb/Q9VBR1" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "Q9VBR1", "url": "https://www.uniprot.org/uniprotkb/Q9VBR1" } ], "pmid": "" }, { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "Q9VBR1", "url": "https://www.uniprot.org/uniprotkb/Q9VBR1" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "Q9VBR1", "url": "https://www.uniprot.org/uniprotkb/Q9VBR1" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "Q9VBR1", "url": "https://www.uniprot.org/uniprotkb/Q9VBR1" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "Q9VBR1", "url": "https://www.uniprot.org/uniprotkb/Q9VBR1" } ], "pmid": "" }, { "name": "cellular response to peptidoglycan", "id": "GO:0071224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071224", "evidence": [ { "database": "UniProtKB", "id": "Q9VBR1", "url": "https://www.uniprot.org/uniprotkb/Q9VBR1" } ], "pmid": "" } ], "cellular_component": [ { "name": "HOPS complex", "id": "GO:0030897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030897", "evidence": [ { "database": "UniProtKB", "id": "Q9VBR1", "url": "https://www.uniprot.org/uniprotkb/Q9VBR1" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "Q9VBR1", "url": "https://www.uniprot.org/uniprotkb/Q9VBR1" } ], "pmid": "" }, { "name": "CORVET complex", "id": "GO:0033263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033263", "evidence": [ { "database": "UniProtKB", "id": "Q9VBR1", "url": "https://www.uniprot.org/uniprotkb/Q9VBR1" } ], "pmid": "" } ], "molecular_function": [ { "name": "syntaxin binding", "id": "GO:0019905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019905", "evidence": [ { "database": "UniProtKB", "id": "Q9VBR1", "url": "https://www.uniprot.org/uniprotkb/Q9VBR1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VBR1-1" }, { "uniprot_canonical_ac": "Q9VBS8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBS8", "url": "https://www.uniprot.org/uniprotkb/Q9VBS8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 396, "chemical_mass": 46342.0, "gene_names": "Dmel\\CG31370;CG13660;CG31370;Dmel\\CG31370;Dmel_CG31370;Dro5-8", "protein_name": "CHK kinase-like domain-containing protein", "disease": [], "molecular_function": [ { "name": "ecdysteroid 22-kinase activity", "id": "GO:0106389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106389", "evidence": [ { "database": "UniProtKB", "id": "Q9VBS8", "url": "https://www.uniprot.org/uniprotkb/Q9VBS8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VBS8-1" }, { "uniprot_canonical_ac": "Q9VBT3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBT3", "url": "https://www.uniprot.org/uniprotkb/Q9VBT3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 422, "chemical_mass": 49276.0, "gene_names": "Dmel\\CG13658;CG13658;Dmel\\CG13658;Dmel_CG13658;Dro5-5", "protein_name": "CHK kinase-like domain-containing protein", "disease": [], "biological_process": [ { "name": "xenobiotic metabolic process", "id": "GO:0006805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006805", "evidence": [ { "database": "UniProtKB", "id": "Q9VBT3", "url": "https://www.uniprot.org/uniprotkb/Q9VBT3" } ], "pmid": "" }, { "name": "cellular response to caffeine", "id": "GO:0071313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071313", "evidence": [ { "database": "UniProtKB", "id": "Q9VBT3", "url": "https://www.uniprot.org/uniprotkb/Q9VBT3" } ], "pmid": "" }, { "name": "detoxification", "id": "GO:0098754", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098754", "evidence": [ { "database": "UniProtKB", "id": "Q9VBT3", "url": "https://www.uniprot.org/uniprotkb/Q9VBT3" } ], "pmid": "" } ], "molecular_function": [ { "name": "ecdysteroid 22-kinase activity", "id": "GO:0106389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106389", "evidence": [ { "database": "UniProtKB", "id": "Q9VBT3", "url": "https://www.uniprot.org/uniprotkb/Q9VBT3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VBT3-1" }, { "uniprot_canonical_ac": "Q9VC06-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VC06", "url": "https://www.uniprot.org/uniprotkb/Q9VC06" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 730, "chemical_mass": 81399.0, "gene_names": "Dmel\\CG11771;CG11771;Dmel\\CG11771;Dmel_CG11771;anon-EST:Posey100", "protein_name": "Peptidase M3A/M3B catalytic domain-containing protein", "disease": [], "cellular_component": [ { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "Q9VC06", "url": "https://www.uniprot.org/uniprotkb/Q9VC06" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VC06", "url": "https://www.uniprot.org/uniprotkb/Q9VC06" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q9VC06", "url": "https://www.uniprot.org/uniprotkb/Q9VC06" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VC06", "url": "https://www.uniprot.org/uniprotkb/Q9VC06" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VC06-1" }, { "uniprot_canonical_ac": "Q9VC08-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VC08", "url": "https://www.uniprot.org/uniprotkb/Q9VC08" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 754, "chemical_mass": 84472.0, "gene_names": "Mink;CG11120;Dmel\\CG11120;Dmel_CG11120;Mink;mink", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q9VC08", "url": "https://www.uniprot.org/uniprotkb/Q9VC08" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q9VC08", "url": "https://www.uniprot.org/uniprotkb/Q9VC08" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VC08", "url": "https://www.uniprot.org/uniprotkb/Q9VC08" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q9VC08", "url": "https://www.uniprot.org/uniprotkb/Q9VC08" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q9VC08", "url": "https://www.uniprot.org/uniprotkb/Q9VC08" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "Q9VC08", "url": "https://www.uniprot.org/uniprotkb/Q9VC08" } ], "pmid": "" } ], "biological_process": [ { "name": "mitotic chromosome condensation", "id": "GO:0007076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007076", "evidence": [ { "database": "UniProtKB", "id": "Q9VC08", "url": "https://www.uniprot.org/uniprotkb/Q9VC08" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "Q9VC08", "url": "https://www.uniprot.org/uniprotkb/Q9VC08" } ], "pmid": "" }, { "name": "establishment of mitotic spindle localization", "id": "GO:0040001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040001", "evidence": [ { "database": "UniProtKB", "id": "Q9VC08", "url": "https://www.uniprot.org/uniprotkb/Q9VC08" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VC08-1" }, { "uniprot_canonical_ac": "Q9VC40-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VC40", "url": "https://www.uniprot.org/uniprotkb/Q9VC40" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 339, "chemical_mass": 37974.0, "gene_names": "Dmel\\CG5805;CG5805;Dmel\\CG5805;Dmel_CG5805", "protein_name": "Solute carrier family 25 member 44", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VC40", "url": "https://www.uniprot.org/uniprotkb/Q9VC40" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VC40", "url": "https://www.uniprot.org/uniprotkb/Q9VC40" } ], "pmid": "" } ], "biological_process": [ { "name": "branched-chain amino acid catabolic process", "id": "GO:0009083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009083", "evidence": [ { "database": "UniProtKB", "id": "Q9VC40", "url": "https://www.uniprot.org/uniprotkb/Q9VC40" } ], "pmid": "" }, { "name": "branched-chain amino acid transport", "id": "GO:0015803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015803", "evidence": [ { "database": "UniProtKB", "id": "Q9VC40", "url": "https://www.uniprot.org/uniprotkb/Q9VC40" } ], "pmid": "" } ], "molecular_function": [ { "name": "branched-chain amino acid transmembrane transporter activity", "id": "GO:0015658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015658", "evidence": [ { "database": "UniProtKB", "id": "Q9VC40", "url": "https://www.uniprot.org/uniprotkb/Q9VC40" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VC40-1" }, { "uniprot_canonical_ac": "Q9VC42-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VC42", "url": "https://www.uniprot.org/uniprotkb/Q9VC42" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1615, "chemical_mass": 179830.0, "gene_names": "CG13632;CG13632;CG42331;CG6879;Dmel\\CG42331;Dmel_CG42331", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VC42", "url": "https://www.uniprot.org/uniprotkb/Q9VC42" } ], "pmid": "" } ], "biological_process": [ { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "Q9VC42", "url": "https://www.uniprot.org/uniprotkb/Q9VC42" } ], "pmid": "" }, { "name": "cellular process involved in reproduction in multicellular organism", "id": "GO:0022412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022412", "evidence": [ { "database": "UniProtKB", "id": "Q9VC42", "url": "https://www.uniprot.org/uniprotkb/Q9VC42" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VC42", "url": "https://www.uniprot.org/uniprotkb/Q9VC42" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9VC42", "url": "https://www.uniprot.org/uniprotkb/Q9VC42" } ], "pmid": "" }, { "name": "peroxidase activity", "id": "GO:0004601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004601", "evidence": [ { "database": "UniProtKB", "id": "Q9VC42", "url": "https://www.uniprot.org/uniprotkb/Q9VC42" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VC42-1" }, { "uniprot_canonical_ac": "Q9VCC7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCC7", "url": "https://www.uniprot.org/uniprotkb/Q9VCC7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 525, "chemical_mass": 59718.0, "gene_names": "Kal1;CG6173;CT19368;DmKal-1;Dmel\\CG6173;Dmel_CG6173;Dmkal;Kal-1;Kal1;kal-1", "protein_name": "", "disease": [ { "disease_id": "DOID:0090094", "name": "hypogonadotropic hypogonadism 1 with or without anosmia", "description": "A hypogonadotropic hypogonadism that has_material_basis_in mutation in the KAL1 gene on chromosome Xp22.3, sometimes in association with mutation in another gene.", "url": "https://disease-ontology.org/term/DOID:0090094", "evidence": [ { "id": "0090094", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090094" } ], "weight": 0.0 }, { "disease_id": "DOID:3614", "name": "Kallmann syndrome", "description": "A hypogonadotropic hypogonadism with a defective sense of smell (anosmia or hyposmia).", "url": "https://disease-ontology.org/term/DOID:3614", "evidence": [ { "id": "3614", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3614" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VCC7", "url": "https://www.uniprot.org/uniprotkb/Q9VCC7" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "Q9VCC7", "url": "https://www.uniprot.org/uniprotkb/Q9VCC7" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "Q9VCC7", "url": "https://www.uniprot.org/uniprotkb/Q9VCC7" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "Q9VCC7", "url": "https://www.uniprot.org/uniprotkb/Q9VCC7" } ], "pmid": "" } ], "molecular_function": [ { "name": "peptidase inhibitor activity", "id": "GO:0030414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030414", "evidence": [ { "database": "UniProtKB", "id": "Q9VCC7", "url": "https://www.uniprot.org/uniprotkb/Q9VCC7" } ], "pmid": "" } ], "biological_process": [ { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "Q9VCC7", "url": "https://www.uniprot.org/uniprotkb/Q9VCC7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VCC7-1" }, { "uniprot_canonical_ac": "Q9VCC8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCC8", "url": "https://www.uniprot.org/uniprotkb/Q9VCC8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 170, "chemical_mass": 18889.0, "gene_names": "Npc2f;BcDNA:LP08842;CG6164;Dmel\\CG6164;Dmel_CG6164;Npc2f;npc2f", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VCC8", "url": "https://www.uniprot.org/uniprotkb/Q9VCC8" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular cholesterol transport", "id": "GO:0032367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032367", "evidence": [ { "database": "UniProtKB", "id": "Q9VCC8", "url": "https://www.uniprot.org/uniprotkb/Q9VCC8" } ], "pmid": "" }, { "name": "sterol transport", "id": "GO:0015918", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015918", "evidence": [ { "database": "UniProtKB", "id": "Q9VCC8", "url": "https://www.uniprot.org/uniprotkb/Q9VCC8" } ], "pmid": "" } ], "molecular_function": [ { "name": "sterol binding", "id": "GO:0032934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032934", "evidence": [ { "database": "UniProtKB", "id": "Q9VCC8", "url": "https://www.uniprot.org/uniprotkb/Q9VCC8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VCC8-1" }, { "uniprot_canonical_ac": "Q9VCD4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCD4", "url": "https://www.uniprot.org/uniprotkb/Q9VCD4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 144, "chemical_mass": 16871.0, "gene_names": "Dmel\\CG18428;CG18428;Dmel\\CG18428;Dmel_CG18428", "protein_name": "ADP-ribosylation factor-like protein 6-interacting protein 4", "disease": [], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q9VCD4", "url": "https://www.uniprot.org/uniprotkb/Q9VCD4" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q9VCD4", "url": "https://www.uniprot.org/uniprotkb/Q9VCD4" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q9VCD4", "url": "https://www.uniprot.org/uniprotkb/Q9VCD4" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "Q9VCD4", "url": "https://www.uniprot.org/uniprotkb/Q9VCD4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VCD4-1" }, { "uniprot_canonical_ac": "Q9VCJ5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VCJ5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 602, "chemical_mass": 64745.0, "gene_names": "prt;CG10251;Dmel\\CG10251;Dmel_CG10251;prt", "protein_name": "", "disease": [], "biological_process": [ { "name": "male mating behavior", "id": "GO:0060179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060179", "evidence": [ { "database": "UniProtKB", "id": "Q9VCJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VCJ5" } ], "pmid": "" }, { "name": "olfactory learning", "id": "GO:0008355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008355", "evidence": [ { "database": "UniProtKB", "id": "Q9VCJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VCJ5" } ], "pmid": "" }, { "name": "aminergic neurotransmitter loading into synaptic vesicle", "id": "GO:0015842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015842", "evidence": [ { "database": "UniProtKB", "id": "Q9VCJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VCJ5" } ], "pmid": "" } ], "cellular_component": [ { "name": "terminal bouton", "id": "GO:0043195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043195", "evidence": [ { "database": "UniProtKB", "id": "Q9VCJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VCJ5" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "Q9VCJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VCJ5" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "Q9VCJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VCJ5" } ], "pmid": "" } ], "molecular_function": [ { "name": "serotonin:sodium:chloride symporter activity", "id": "GO:0005335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005335", "evidence": [ { "database": "UniProtKB", "id": "Q9VCJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VCJ5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VCJ5-1" }, { "uniprot_canonical_ac": "Q9VCK7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCK7", "url": "https://www.uniprot.org/uniprotkb/Q9VCK7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 685, "chemical_mass": 77441.0, "gene_names": "Dmel\\CG10183;CG10183;Dmel\\CG10183;Dmel_CG10183", "protein_name": "Nose resistant-to-fluoxetine protein N-terminal domain-containing protein", "disease": [], "molecular_function": [ { "name": "acyltransferase activity, transferring groups other than amino-acyl groups", "id": "GO:0016747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016747", "evidence": [ { "database": "UniProtKB", "id": "Q9VCK7", "url": "https://www.uniprot.org/uniprotkb/Q9VCK7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VCK7-1" }, { "uniprot_canonical_ac": "Q9VCL2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCL2", "url": "https://www.uniprot.org/uniprotkb/Q9VCL2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 386, "chemical_mass": 43324.0, "gene_names": "NEST:bs02f09;CG10164;Dmel\\CG10164;Dmel_CG10164;NEST:bs02f09", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VCL2-1", "start_pos": "180", "end_pos": "180", "site_lbl": "Thr180", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 180, "start_aa": "Thr", "end_pos": 180, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr180", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "Q9VCL2-1" }, { "uniprot_canonical_ac": "Q9VCQ8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCQ8", "url": "https://www.uniprot.org/uniprotkb/Q9VCQ8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 401, "chemical_mass": 45052.0, "gene_names": "Dmel\\CG6738;CG6738;Dmel\\CG6738;Dmel_CG6738", "protein_name": "N-acyl-aliphatic-L-amino acid amidohydrolase", "disease": [], "molecular_function": [ { "name": "aminoacylase activity", "id": "GO:0004046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004046", "evidence": [ { "database": "UniProtKB", "id": "Q9VCQ8", "url": "https://www.uniprot.org/uniprotkb/Q9VCQ8" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VCQ8", "url": "https://www.uniprot.org/uniprotkb/Q9VCQ8" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VCQ8", "url": "https://www.uniprot.org/uniprotkb/Q9VCQ8" } ], "pmid": "" } ], "biological_process": [ { "name": "amino acid metabolic process", "id": "GO:0006520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006520", "evidence": [ { "database": "UniProtKB", "id": "Q9VCQ8", "url": "https://www.uniprot.org/uniprotkb/Q9VCQ8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VCQ8-1" }, { "uniprot_canonical_ac": "Q9VCR2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCR2", "url": "https://www.uniprot.org/uniprotkb/Q9VCR2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 401, "chemical_mass": 44998.0, "gene_names": "Dmel\\CG6726;CG6726;Dmel\\CG6726;Dmel_CG6726", "protein_name": "N-acyl-aliphatic-L-amino acid amidohydrolase", "disease": [], "molecular_function": [ { "name": "aminoacylase activity", "id": "GO:0004046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004046", "evidence": [ { "database": "UniProtKB", "id": "Q9VCR2", "url": "https://www.uniprot.org/uniprotkb/Q9VCR2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VCR2", "url": "https://www.uniprot.org/uniprotkb/Q9VCR2" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VCR2", "url": "https://www.uniprot.org/uniprotkb/Q9VCR2" } ], "pmid": "" } ], "biological_process": [ { "name": "amino acid metabolic process", "id": "GO:0006520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006520", "evidence": [ { "database": "UniProtKB", "id": "Q9VCR2", "url": "https://www.uniprot.org/uniprotkb/Q9VCR2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VCR2-1" }, { "uniprot_canonical_ac": "Q9VCS1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCS1", "url": "https://www.uniprot.org/uniprotkb/Q9VCS1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 91, "chemical_mass": 10132.0, "gene_names": "Dmel\\CG13838;CG13838;Dmel\\CG13838;Dmel_CG13838", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VCS1-1" }, { "uniprot_canonical_ac": "Q9VD15-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VD15", "url": "https://www.uniprot.org/uniprotkb/Q9VD15" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 706, "chemical_mass": 83885.0, "gene_names": "Dmel\\CG13855;CG13855;Dmel\\CG13855;Dmel_CG13855", "protein_name": "IQ motif and ubiquitin-like domain-containing protein", "disease": [], "cellular_component": [ { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "Q9VD15", "url": "https://www.uniprot.org/uniprotkb/Q9VD15" } ], "pmid": "" }, { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "Q9VD15", "url": "https://www.uniprot.org/uniprotkb/Q9VD15" } ], "pmid": "" } ], "biological_process": [ { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "Q9VD15", "url": "https://www.uniprot.org/uniprotkb/Q9VD15" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "Q9VD15", "url": "https://www.uniprot.org/uniprotkb/Q9VD15" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VD15-1" }, { "uniprot_canonical_ac": "Q9VD23-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VD23", "url": "https://www.uniprot.org/uniprotkb/Q9VD23" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 744, "chemical_mass": 83997.0, "gene_names": "Pykl1;CG7069;Dmel\\CG7069;Dmel_CG7069", "protein_name": "Pyruvate kinase", "disease": [ { "disease_id": "DOID:0111077", "name": "congenital nonspherocytic hemolytic anemia 2", "description": "A congenital nonspherocytic hemolytic anemia that has_material_basis_in homozygous or compound heterozygous mutation in the PKLR gene on chromosome 1q22.", "url": "https://disease-ontology.org/term/DOID:0111077", "evidence": [ { "id": "0111077", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111077" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:12365", "name": "malaria", "description": "A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle.", "url": "https://disease-ontology.org/term/DOID:12365", "evidence": [ { "id": "12365", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12365" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "Q9VD23", "url": "https://www.uniprot.org/uniprotkb/Q9VD23" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VD23", "url": "https://www.uniprot.org/uniprotkb/Q9VD23" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "Q9VD23", "url": "https://www.uniprot.org/uniprotkb/Q9VD23" } ], "pmid": "" }, { "name": "potassium ion binding", "id": "GO:0030955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030955", "evidence": [ { "database": "UniProtKB", "id": "Q9VD23", "url": "https://www.uniprot.org/uniprotkb/Q9VD23" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VD23", "url": "https://www.uniprot.org/uniprotkb/Q9VD23" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VD23", "url": "https://www.uniprot.org/uniprotkb/Q9VD23" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VD23", "url": "https://www.uniprot.org/uniprotkb/Q9VD23" } ], "pmid": "" } ], "biological_process": [ { "name": "glycolytic process", "id": "GO:0006096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006096", "evidence": [ { "database": "UniProtKB", "id": "Q9VD23", "url": "https://www.uniprot.org/uniprotkb/Q9VD23" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VD23-1" }, { "uniprot_canonical_ac": "Q9VD33-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VD33", "url": "https://www.uniprot.org/uniprotkb/Q9VD33" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 177, "chemical_mass": 20221.0, "gene_names": "Dmel\\CG5391;CG5391;Dmel\\CG5391;Dmel_CG5391", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VD33-1" }, { "uniprot_canonical_ac": "Q9VD65-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VD65", "url": "https://www.uniprot.org/uniprotkb/Q9VD65" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 186, "chemical_mass": 21131.0, "gene_names": "BcDNA:LP07781;BcDNA:LP07781;CG17819;Dmel\\CG17819;Dmel_CG17819", "protein_name": "ADP-ribosylation factor-related protein 1", "disease": [], "biological_process": [ { "name": "system development", "id": "GO:0048731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048731", "evidence": [ { "database": "UniProtKB", "id": "Q9VD65", "url": "https://www.uniprot.org/uniprotkb/Q9VD65" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "Q9VD65", "url": "https://www.uniprot.org/uniprotkb/Q9VD65" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "Q9VD65", "url": "https://www.uniprot.org/uniprotkb/Q9VD65" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q9VD65", "url": "https://www.uniprot.org/uniprotkb/Q9VD65" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q9VD65", "url": "https://www.uniprot.org/uniprotkb/Q9VD65" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VD65", "url": "https://www.uniprot.org/uniprotkb/Q9VD65" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VD65", "url": "https://www.uniprot.org/uniprotkb/Q9VD65" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q9VD65", "url": "https://www.uniprot.org/uniprotkb/Q9VD65" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VD65-1" }, { "uniprot_canonical_ac": "Q9VDC0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDC0", "url": "https://www.uniprot.org/uniprotkb/Q9VDC0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 250, "chemical_mass": 27236.0, "gene_names": "FOHSDR;CG3301;Dmel\\CG3301;Dmel_CG3301;FOHSDR", "protein_name": "", "disease": [], "molecular_function": [ { "name": "17-beta-hydroxysteroid dehydrogenase (NADP+) activity", "id": "GO:0072582", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072582", "evidence": [ { "database": "UniProtKB", "id": "Q9VDC0", "url": "https://www.uniprot.org/uniprotkb/Q9VDC0" } ], "pmid": "" }, { "name": "estradiol 17-beta-dehydrogenase [NAD(P)+] activity", "id": "GO:0004303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004303", "evidence": [ { "database": "UniProtKB", "id": "Q9VDC0", "url": "https://www.uniprot.org/uniprotkb/Q9VDC0" } ], "pmid": "" }, { "name": "3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity", "id": "GO:0000253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000253", "evidence": [ { "database": "UniProtKB", "id": "Q9VDC0", "url": "https://www.uniprot.org/uniprotkb/Q9VDC0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VDC0-1" }, { "uniprot_canonical_ac": "Q9VDF8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDF8", "url": "https://www.uniprot.org/uniprotkb/Q9VDF8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 258, "chemical_mass": 30085.0, "gene_names": "Dmel\\CG31189;CG31189;CG7096-C;CG7096;Dmel\\CG31189;Dmel_CG31189", "protein_name": "Protein takeout", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VDF8", "url": "https://www.uniprot.org/uniprotkb/Q9VDF8" } ], "pmid": "" } ], "biological_process": [ { "name": "circadian rhythm", "id": "GO:0007623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007623", "evidence": [ { "database": "UniProtKB", "id": "Q9VDF8", "url": "https://www.uniprot.org/uniprotkb/Q9VDF8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VDF8-1" }, { "uniprot_canonical_ac": "Q9VDK7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDK7", "url": "https://www.uniprot.org/uniprotkb/Q9VDK7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 650, "chemical_mass": 72851.0, "gene_names": "Srp72;CG5434;Dmel\\CG5434;Dmel_CG5434;SRP72;Srp72", "protein_name": "Signal recognition particle subunit SRP72", "disease": [], "cellular_component": [ { "name": "signal recognition particle, endoplasmic reticulum targeting", "id": "GO:0005786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005786", "evidence": [ { "database": "UniProtKB", "id": "Q9VDK7", "url": "https://www.uniprot.org/uniprotkb/Q9VDK7" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q9VDK7", "url": "https://www.uniprot.org/uniprotkb/Q9VDK7" } ], "pmid": "" } ], "biological_process": [ { "name": "SRP-dependent cotranslational protein targeting to membrane", "id": "GO:0006614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006614", "evidence": [ { "database": "UniProtKB", "id": "Q9VDK7", "url": "https://www.uniprot.org/uniprotkb/Q9VDK7" } ], "pmid": "" }, { "name": "SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition", "id": "GO:0006617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006617", "evidence": [ { "database": "UniProtKB", "id": "Q9VDK7", "url": "https://www.uniprot.org/uniprotkb/Q9VDK7" } ], "pmid": "" } ], "molecular_function": [ { "name": "7S RNA binding", "id": "GO:0008312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008312", "evidence": [ { "database": "UniProtKB", "id": "Q9VDK7", "url": "https://www.uniprot.org/uniprotkb/Q9VDK7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VDK7-1" }, { "uniprot_canonical_ac": "Q9VDL0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDL0", "url": "https://www.uniprot.org/uniprotkb/Q9VDL0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 109, "chemical_mass": 12418.0, "gene_names": "Srp14;BcDNA:RE48595;CG5417;Dmel\\CG5417;Dmel_CG5417;SRP14;Srp14", "protein_name": "Signal recognition particle 14 kDa protein", "disease": [], "cellular_component": [ { "name": "signal recognition particle, endoplasmic reticulum targeting", "id": "GO:0005786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005786", "evidence": [ { "database": "UniProtKB", "id": "Q9VDL0", "url": "https://www.uniprot.org/uniprotkb/Q9VDL0" } ], "pmid": "" } ], "molecular_function": [ { "name": "endoplasmic reticulum signal peptide binding", "id": "GO:0030942", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030942", "evidence": [ { "database": "UniProtKB", "id": "Q9VDL0", "url": "https://www.uniprot.org/uniprotkb/Q9VDL0" } ], "pmid": "" }, { "name": "7S RNA binding", "id": "GO:0008312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008312", "evidence": [ { "database": "UniProtKB", "id": "Q9VDL0", "url": "https://www.uniprot.org/uniprotkb/Q9VDL0" } ], "pmid": "" } ], "biological_process": [ { "name": "protein targeting to ER", "id": "GO:0045047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045047", "evidence": [ { "database": "UniProtKB", "id": "Q9VDL0", "url": "https://www.uniprot.org/uniprotkb/Q9VDL0" } ], "pmid": "" }, { "name": "SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition", "id": "GO:0006617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006617", "evidence": [ { "database": "UniProtKB", "id": "Q9VDL0", "url": "https://www.uniprot.org/uniprotkb/Q9VDL0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VDL0-1" }, { "uniprot_canonical_ac": "Q9VDN4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDN4", "url": "https://www.uniprot.org/uniprotkb/Q9VDN4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 556, "chemical_mass": 60441.0, "gene_names": "Sag1;CG4360;Dmel\\CG4360;Dmel_CG4360", "protein_name": "C2H2-type domain-containing protein", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "Q9VDN4", "url": "https://www.uniprot.org/uniprotkb/Q9VDN4" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VDN4", "url": "https://www.uniprot.org/uniprotkb/Q9VDN4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VDN4", "url": "https://www.uniprot.org/uniprotkb/Q9VDN4" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VDN4", "url": "https://www.uniprot.org/uniprotkb/Q9VDN4" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "Q9VDN4", "url": "https://www.uniprot.org/uniprotkb/Q9VDN4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q9VDN4", "url": "https://www.uniprot.org/uniprotkb/Q9VDN4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "Q9VDN4-1" } ]