{
    "disease_id": "DOID:0111428",
    "recommended_name": {
        "id": "DOID:0111428",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0111428",
        "name": "essential tremor 1",
        "description": "An essential tremor that has_material_basis_in heterozygous mutation in the DRD3 gene on chromosome 3q13.31."
    },
    "synonyms": [
        {
            "id": "DOID:0111428",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0111428",
            "name": "ETM1",
            "description": ""
        },
        {
            "id": "DOID:0111428",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0111428",
            "name": "hereditary essential tremor 1",
            "description": ""
        },
        {
            "id": "MONDO:0008590",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008590",
            "name": "tremor, hereditary essential, 1",
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        },
        {
            "id": "MONDO:0008590",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008590",
            "name": "DRD3 essential tremor",
            "description": ""
        },
        {
            "id": "MONDO:0008590",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008590",
            "name": "essential tremor caused by mutation in DRD3",
            "description": ""
        },
        {
            "id": "MONDO:0008590",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008590",
            "name": "essential tremor, hereditary, 1",
            "description": ""
        },
        {
            "id": "MONDO:0008590",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008590",
            "name": "tremor, hereditary essential, 1",
            "description": ""
        },
        {
            "id": "MONDO:0008590",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008590",
            "name": "tremor, hereditary essential, type 1",
            "description": ""
        },
        {
            "id": "MONDO:0008590",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008590",
            "name": "ETM1",
            "description": ""
        },
        {
            "id": "MONDO:0008590",
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            "url": "https://monarchinitiative.org/disease/MONDO:0008590",
            "name": "FET1",
            "description": ""
        },
        {
            "id": "MONDO:0008590",
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            "url": "https://monarchinitiative.org/disease/MONDO:0008590",
            "name": "tremor familial essential, 1",
            "description": ""
        },
        {
            "id": "MONDO:0008590",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008590",
            "name": "tremor hereditary essential, 1",
            "description": ""
        },
        {
            "id": "MIM:190300",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/190300",
            "name": "Tremor, hereditary essential 1",
            "description": "Tremor, hereditary essential 1"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0111428"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0111428",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0111428",
            "categories": []
        },
        {
            "id": "MONDO:0008590",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008590",
            "categories": []
        },
        {
            "id": "MIM:190300",
            "database": "MIM",
            "url": "https://www.omim.org/entry/190300",
            "categories": []
        }
    ],
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        {
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            "uniprot_ac": "F1QG18",
            "uniprot_id": "F1QG18_DANRE",
            "refseq_ac": "XP_005162730",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "D(3) dopamine receptor",
                    "type": "recommended"
                },
                {
                    "name": "D(3) dopamine receptor isoform X1",
                    "type": "synonym"
                },
                {
                    "name": "Dopamine D3 receptor",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "drd3",
                    "type": "recommended"
                },
                {
                    "name": "drd3",
                    "type": "synonym"
                }
            ],
            "record_id": "F1QG18-1",
            "evidence": [
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                    "id": "0111428",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111428"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P30728-1",
            "uniprot_ac": "P30728",
            "uniprot_id": "DRD3_MOUSE",
            "refseq_ac": "NP_031903",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
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                    "name": "D(3) dopamine receptor",
                    "type": "recommended"
                },
                {
                    "name": "D(3) dopamine receptor",
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                },
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                    "name": "Dopamine D3 receptor",
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                },
                {
                    "name": "dopamine D3 receptor",
                    "type": "synonym"
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                {
                    "name": "dopamine receptor 3",
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            ],
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                {
                    "name": "Drd3",
                    "type": "recommended"
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                    "name": "D3R",
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                },
                {
                    "name": "Drd3",
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            ],
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            ]
        },
        {
            "uniprot_canonical_ac": "P35462-1",
            "uniprot_ac": "P35462",
            "uniprot_id": "DRD3_HUMAN",
            "refseq_ac": "NP_000787",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "D(3) dopamine receptor",
                    "type": "recommended"
                },
                {
                    "name": "D(3) dopamine receptor isoform a",
                    "type": "synonym"
                },
                {
                    "name": "Dopamine D3 receptor",
                    "type": "synonym"
                },
                {
                    "name": "essential tremor 1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "DRD3",
                    "type": "recommended"
                },
                {
                    "name": "D3DR",
                    "type": "synonym"
                },
                {
                    "name": "DRD3",
                    "type": "synonym"
                },
                {
                    "name": "ETM1",
                    "type": "synonym"
                },
                {
                    "name": "FET1",
                    "type": "synonym"
                }
            ],
            "record_id": "P35462-1",
            "evidence": [
                {
                    "id": "190300",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/190300"
                },
                {
                    "id": "0111428",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111428"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P19020-1",
            "uniprot_ac": "P19020",
            "uniprot_id": "DRD3_RAT",
            "refseq_ac": "NP_058836",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "D(3) dopamine receptor",
                    "type": "recommended"
                },
                {
                    "name": "D(3) dopamine receptor",
                    "type": "synonym"
                },
                {
                    "name": "Dopamine D3 receptor",
                    "type": "synonym"
                },
                {
                    "name": "dopaminergic receptor D3",
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            ],
            "gene_names": [
                {
                    "name": "Drd3",
                    "type": "recommended"
                },
                {
                    "name": "Drd3",
                    "type": "synonym"
                }
            ],
            "record_id": "P19020-1",
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                    "url": "https://www.alliancegenome.org/disease/DOID:0111428"
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        },
        {
            "uniprot_canonical_ac": "Q8IS44-1",
            "uniprot_ac": "Q8IS44",
            "uniprot_id": "DRD2L_DROME",
            "refseq_ac": "NP_001014757",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Drosophila melanogaster",
                    "taxid": 7227,
                    "common_name": "Fruit fly",
                    "glygen_name": "Fruit fly",
                    "reference_species": "Drosophila melanogaster [7227]"
                }
            ],
            "protein_names": [
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                    "name": "Dopamine D2-like receptor",
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                    "name": "CG33517-PF",
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                    "name": "D2 autoreceptor",
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                    "name": "D2-like receptor",
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                    "name": "D[[2]] receptor",
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                    "name": "CG9569",
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                    "name": "DD2R",
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                    "name": "DmDOP3",
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                    "name": "Dmel\\CG33517",
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            "uniprot_ac": "P17538",
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                    "name": "Homo sapiens",
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                    "name": "Chymotrypsinogen B",
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                    "name": "3.4.21.1",
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                    "name": "chymotrypsinogen B isoform 2 precursor",
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    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0111428"
}