{
    "disease_id": "DOID:0081225",
    "recommended_name": {
        "id": "DOID:0081225",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0081225",
        "name": "autosomal recessive intellectual developmental disorder 64",
        "description": "An autosomal recessive intellectual developmental disorder that has_material_basis_in homozygous mutation in the LINGO1 gene on chromosome 15q24."
    },
    "synonyms": [
        {
            "id": "MONDO:0020846",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0020846",
            "name": "intellectual disability, autosomal recessive 64",
            "description": ""
        },
        {
            "id": "MONDO:0020846",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0020846",
            "name": "MENTAL RETARDATION, autosomal recessive 64",
            "description": ""
        },
        {
            "id": "MONDO:0020846",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0020846",
            "name": "MRT64",
            "description": ""
        },
        {
            "id": "MIM:618103",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/618103",
            "name": "Intellectual developmental disorder, autosomal recessive 64",
            "description": "Intellectual developmental disorder, autosomal recessive 64"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0081225"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0081225",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0081225",
            "categories": []
        },
        {
            "id": "MONDO:0020846",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0020846",
            "categories": []
        },
        {
            "id": "MIM:618103",
            "database": "MIM",
            "url": "https://www.omim.org/entry/618103",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "Q66HV9-1",
            "uniprot_ac": "Q66HV9",
            "uniprot_id": "LIG1B_DANRE",
            "refseq_ac": "NP_001004576",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1-B",
                    "type": "recommended"
                },
                {
                    "name": "leucine-rich repeat and Ig-domain containing 1",
                    "type": "synonym"
                },
                {
                    "name": "leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1-B precursor",
                    "type": "synonym"
                },
                {
                    "name": "leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1-B",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "lingo1b",
                    "type": "recommended"
                },
                {
                    "name": "lingo1b",
                    "type": "synonym"
                },
                {
                    "name": "lingo1",
                    "type": "synonym"
                },
                {
                    "name": "si:ch211-116a8.1",
                    "type": "synonym"
                },
                {
                    "name": "zgc:92338",
                    "type": "synonym"
                }
            ],
            "record_id": "Q66HV9-1",
            "evidence": [
                {
                    "id": "0081225",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0081225"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9D1T0-1",
            "uniprot_ac": "Q9D1T0",
            "uniprot_id": "LIGO1_MOUSE",
            "refseq_ac": "NP_001298005",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1",
                    "type": "recommended"
                },
                {
                    "name": "Leucine-rich repeat neuronal protein 1",
                    "type": "synonym"
                },
                {
                    "name": "Leucine-rich repeat neuronal protein 6A",
                    "type": "synonym"
                },
                {
                    "name": "leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform 1 precursor",
                    "type": "synonym"
                },
                {
                    "name": "leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1",
                    "type": "synonym"
                },
                {
                    "name": "leucine-rich repeat neuronal protein 1",
                    "type": "synonym"
                },
                {
                    "name": "leucine-rich repeat neuronal protein 6A",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Lingo1",
                    "type": "recommended"
                },
                {
                    "name": "4930471K13Rik",
                    "type": "synonym"
                },
                {
                    "name": "LERN1",
                    "type": "synonym"
                },
                {
                    "name": "LINGO-1",
                    "type": "synonym"
                },
                {
                    "name": "Lern1",
                    "type": "synonym"
                },
                {
                    "name": "Lingo1",
                    "type": "synonym"
                },
                {
                    "name": "Lrrn6a",
                    "type": "synonym"
                },
                {
                    "name": "UNQ201",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9D1T0-1",
            "evidence": [
                {
                    "id": "0081225",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0081225"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q96FE5-1",
            "uniprot_ac": "Q96FE5",
            "uniprot_id": "LIGO1_HUMAN",
            "refseq_ac": "NP_001288115",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1",
                    "type": "recommended"
                },
                {
                    "name": "Leucine-rich repeat and immunoglobulin domain-containing protein 1",
                    "type": "synonym"
                },
                {
                    "name": "Leucine-rich repeat neuronal protein 1",
                    "type": "synonym"
                },
                {
                    "name": "Leucine-rich repeat neuronal protein 6A",
                    "type": "synonym"
                },
                {
                    "name": "leucine rich repeat neuronal 6A",
                    "type": "synonym"
                },
                {
                    "name": "leucine-rich repeat and immunoglobulin domain-containing protein 1",
                    "type": "synonym"
                },
                {
                    "name": "leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform b precursor",
                    "type": "synonym"
                },
                {
                    "name": "leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1",
                    "type": "synonym"
                },
                {
                    "name": "leucine-rich repeat neuronal protein 1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "LINGO1",
                    "type": "recommended"
                },
                {
                    "name": "LERN1",
                    "type": "synonym"
                },
                {
                    "name": "LINGO1",
                    "type": "synonym"
                },
                {
                    "name": "LRRN6A",
                    "type": "synonym"
                },
                {
                    "name": "MRT64",
                    "type": "synonym"
                },
                {
                    "name": "PRO227",
                    "type": "synonym"
                },
                {
                    "name": "UNQ201",
                    "type": "synonym"
                }
            ],
            "record_id": "Q96FE5-1",
            "evidence": [
                {
                    "id": "618103",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/618103"
                },
                {
                    "id": "0081225",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0081225"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A8I5ZPI2-1",
            "uniprot_ac": "A0A8I5ZPI2",
            "uniprot_id": "A0A8I5ZPI2_RAT",
            "refseq_ac": "XP_006243182",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Leucine rich repeat and Ig domain containing 1",
                    "type": "synonym"
                },
                {
                    "name": "leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform X1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Lingo1",
                    "type": "recommended"
                },
                {
                    "name": "Lingo1",
                    "type": "synonym"
                },
                {
                    "name": "Lrrn6a",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A8I5ZPI2-1",
            "evidence": [
                {
                    "id": "0081225",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0081225"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0081225"
}