{
    "disease_id": "DOID:0080241",
    "recommended_name": {
        "id": "DOID:0080241",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0080241",
        "name": "syndromic X-linked mental retardation 35",
        "description": "A syndromic X-linked intellectual disability that has_material_basis_in mutation in the RPL10 gene on chromosome Xq28."
    },
    "synonyms": [
        {
            "id": "MONDO:0030908",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0030908",
            "name": "intellectual disability, X-linked, syndromic, 35",
            "description": ""
        },
        {
            "id": "MONDO:0030908",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0030908",
            "name": "intellectual developmental disorder, X-linked, syndromic, 35, X-linked recessive",
            "description": ""
        },
        {
            "id": "MONDO:0030908",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0030908",
            "name": "intellectual disability, X-linked, syndromic, 35",
            "description": ""
        },
        {
            "id": "MONDO:0030908",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0030908",
            "name": "MRXS35",
            "description": ""
        },
        {
            "id": "MONDO:0030908",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0030908",
            "name": "mental retardation, X-linked, syndromic, 35",
            "description": ""
        },
        {
            "id": "MONDO:0030908",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0030908",
            "name": "syndromic X-linked mental retardation 35",
            "description": ""
        },
        {
            "id": "MIM:300998",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/300998",
            "name": "Intellectual developmental disorder, X-linked, syndromic 35",
            "description": "Intellectual developmental disorder, X-linked, syndromic 35"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0080241"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0080241",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0080241",
            "categories": []
        },
        {
            "id": "MONDO:0030908",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0030908",
            "categories": []
        },
        {
            "id": "MIM:300998",
            "database": "MIM",
            "url": "https://www.omim.org/entry/300998",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "Q7ZV96-1",
            "uniprot_ac": "Q7ZV96",
            "uniprot_id": "RL10_DANRE",
            "refseq_ac": "NP_956321",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Large ribosomal subunit protein uL16",
                    "type": "recommended"
                },
                {
                    "name": "60S ribosomal protein L10",
                    "type": "synonym"
                },
                {
                    "name": "Protein QM",
                    "type": "synonym"
                },
                {
                    "name": "Ribosomal protein L10",
                    "type": "synonym"
                },
                {
                    "name": "associated with tumor suppression, cell growth, differentiation, development and apoptosis",
                    "type": "synonym"
                },
                {
                    "name": "large ribosomal subunit protein uL16",
                    "type": "synonym"
                },
                {
                    "name": "protein QM",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "rpl10",
                    "type": "recommended"
                },
                {
                    "name": "QM protein",
                    "type": "synonym"
                },
                {
                    "name": "QM",
                    "type": "synonym"
                },
                {
                    "name": "fa93d03",
                    "type": "synonym"
                },
                {
                    "name": "rpl-10",
                    "type": "synonym"
                },
                {
                    "name": "rpl10",
                    "type": "synonym"
                },
                {
                    "name": "wu:fa93d03",
                    "type": "synonym"
                },
                {
                    "name": "zgc:56154",
                    "type": "synonym"
                }
            ],
            "record_id": "Q7ZV96-1",
            "evidence": [
                {
                    "id": "0080241",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080241"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q6ZWV3-1",
            "uniprot_ac": "Q6ZWV3",
            "uniprot_id": "RL10_MOUSE",
            "refseq_ac": "NP_443067",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Large ribosomal subunit protein uL16",
                    "type": "recommended"
                },
                {
                    "name": "24.6 kDa protein",
                    "type": "synonym"
                },
                {
                    "name": "24.6kDa protein",
                    "type": "synonym"
                },
                {
                    "name": "60S ribosomal protein L10",
                    "type": "synonym"
                },
                {
                    "name": "Protein QM homolog",
                    "type": "synonym"
                },
                {
                    "name": "Ribosomal protein L10",
                    "type": "synonym"
                },
                {
                    "name": "large ribosomal subunit protein uL16",
                    "type": "synonym"
                },
                {
                    "name": "protein QM homolog",
                    "type": "synonym"
                },
                {
                    "name": "ribosomal protein 10",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Rpl10",
                    "type": "recommended"
                },
                {
                    "name": "D0HXS648",
                    "type": "synonym"
                },
                {
                    "name": "DXHXS648E",
                    "type": "synonym"
                },
                {
                    "name": "DXHXS648",
                    "type": "synonym"
                },
                {
                    "name": "QM16",
                    "type": "synonym"
                },
                {
                    "name": "QM",
                    "type": "synonym"
                },
                {
                    "name": "Qm",
                    "type": "synonym"
                },
                {
                    "name": "Rpl10",
                    "type": "synonym"
                }
            ],
            "record_id": "Q6ZWV3-1",
            "evidence": [
                {
                    "id": "0080241",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080241"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P27635-1",
            "uniprot_ac": "P27635",
            "uniprot_id": "RL10_HUMAN",
            "refseq_ac": "NP_001243506",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Large ribosomal subunit protein uL16",
                    "type": "recommended"
                },
                {
                    "name": "60S ribosomal protein L10",
                    "type": "synonym"
                },
                {
                    "name": "Laminin receptor homolog",
                    "type": "synonym"
                },
                {
                    "name": "Protein QM",
                    "type": "synonym"
                },
                {
                    "name": "Ribosomal protein L10",
                    "type": "synonym"
                },
                {
                    "name": "Tumor suppressor QM",
                    "type": "synonym"
                },
                {
                    "name": "Wilms tumor-related protein",
                    "type": "synonym"
                },
                {
                    "name": "laminin receptor homolog",
                    "type": "synonym"
                },
                {
                    "name": "large ribosomal subunit protein uL16 isoform b",
                    "type": "synonym"
                },
                {
                    "name": "large ribosomal subunit protein uL16",
                    "type": "synonym"
                },
                {
                    "name": "tumor suppressor QM",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "RPL10",
                    "type": "recommended"
                },
                {
                    "name": "AUTSX5",
                    "type": "synonym"
                },
                {
                    "name": "DXS648E",
                    "type": "synonym"
                },
                {
                    "name": "DXS648",
                    "type": "synonym"
                },
                {
                    "name": "L10",
                    "type": "synonym"
                },
                {
                    "name": "MRXS35",
                    "type": "synonym"
                },
                {
                    "name": "NOV",
                    "type": "synonym"
                },
                {
                    "name": "QM",
                    "type": "synonym"
                },
                {
                    "name": "RPL10",
                    "type": "synonym"
                },
                {
                    "name": "uL16",
                    "type": "synonym"
                }
            ],
            "record_id": "P27635-1",
            "evidence": [
                {
                    "id": "300998",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/300998"
                },
                {
                    "id": "0080241",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080241"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P41805-1",
            "uniprot_ac": "P41805",
            "uniprot_id": "RL10_YEAST",
            "refseq_ac": "NP_013176",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Saccharomyces cerevisiae S288C",
                    "taxid": 559292,
                    "common_name": "Baker's yeast",
                    "glygen_name": "Yeast",
                    "reference_species": "Saccharomyces cerevisiae S288C [559292]"
                }
            ],
            "protein_names": [
                {
                    "name": "Large ribosomal subunit protein uL16",
                    "type": "recommended"
                },
                {
                    "name": "60S ribosomal protein L10",
                    "type": "synonym"
                },
                {
                    "name": "60S ribosomal protein uL16 RPL10",
                    "type": "synonym"
                },
                {
                    "name": "L9",
                    "type": "synonym"
                },
                {
                    "name": "Ubiquinol-cytochrome C reductase complex subunit VI-requiring protein",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "RPL10",
                    "type": "recommended"
                },
                {
                    "name": "GRC5",
                    "type": "synonym"
                },
                {
                    "name": "QSR1",
                    "type": "synonym"
                },
                {
                    "name": "RPL10",
                    "type": "synonym"
                }
            ],
            "record_id": "P41805-1",
            "evidence": [
                {
                    "id": "0080241",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080241"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q6PDV7-1",
            "uniprot_ac": "Q6PDV7",
            "uniprot_id": "RL10_RAT",
            "refseq_ac": "NP_112362",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Large ribosomal subunit protein uL16",
                    "type": "recommended"
                },
                {
                    "name": "60S ribosomal protein L10",
                    "type": "synonym"
                },
                {
                    "name": "Ribosomal protein L10",
                    "type": "synonym"
                },
                {
                    "name": "large ribosomal subunit protein uL16",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Rpl10",
                    "type": "recommended"
                },
                {
                    "name": "Rpl10",
                    "type": "synonym"
                }
            ],
            "record_id": "Q6PDV7-1",
            "evidence": [
                {
                    "id": "0080241",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080241"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A8I5ZQF6-1",
            "uniprot_ac": "A0A8I5ZQF6",
            "uniprot_id": "A0A8I5ZQF6_RAT",
            "refseq_ac": "XP_574109",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Ribosomal protein L10, pseudogene 14",
                    "type": "synonym"
                },
                {
                    "name": "large ribosomal subunit protein uL16-like",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Rpl10-ps14",
                    "type": "recommended"
                },
                {
                    "name": "Rpl10-ps14",
                    "type": "synonym"
                },
                {
                    "name": "Rpl10l2",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A8I5ZQF6-1",
            "evidence": [
                {
                    "id": "0080241",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080241"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "O61231-1",
            "uniprot_ac": "O61231",
            "uniprot_id": "RL10_DROME",
            "refseq_ac": "NP_001262233",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Drosophila melanogaster",
                    "taxid": 7227,
                    "common_name": "Fruit fly",
                    "glygen_name": "Fruit fly",
                    "reference_species": "Drosophila melanogaster [7227]"
                }
            ],
            "protein_names": [
                {
                    "name": "Large ribosomal subunit protein uL16",
                    "type": "recommended"
                },
                {
                    "name": "60S ribosomal protein L10",
                    "type": "synonym"
                },
                {
                    "name": "CG17521-PE",
                    "type": "synonym"
                },
                {
                    "name": "QM protein homolog",
                    "type": "synonym"
                },
                {
                    "name": "Qm",
                    "type": "synonym"
                },
                {
                    "name": "RpL10-PE",
                    "type": "synonym"
                },
                {
                    "name": "dQM",
                    "type": "synonym"
                },
                {
                    "name": "ribosomal protein L10, isoform E",
                    "type": "synonym"
                },
                {
                    "name": "ribosome RL10",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "RpL10",
                    "type": "recommended"
                },
                {
                    "name": "BcDNA:LD24589",
                    "type": "synonym"
                },
                {
                    "name": "CG17521",
                    "type": "synonym"
                },
                {
                    "name": "DQM",
                    "type": "synonym"
                },
                {
                    "name": "Dmel\\CG17521",
                    "type": "synonym"
                },
                {
                    "name": "Dmel_CG17521",
                    "type": "synonym"
                },
                {
                    "name": "L10",
                    "type": "synonym"
                },
                {
                    "name": "L16",
                    "type": "synonym"
                },
                {
                    "name": "Qm",
                    "type": "synonym"
                },
                {
                    "name": "Rp L10",
                    "type": "synonym"
                },
                {
                    "name": "RpL10",
                    "type": "synonym"
                },
                {
                    "name": "anon-EST:Posey179",
                    "type": "synonym"
                },
                {
                    "name": "qm",
                    "type": "synonym"
                },
                {
                    "name": "rpL10",
                    "type": "synonym"
                }
            ],
            "record_id": "O61231-1",
            "evidence": [
                {
                    "id": "0080241",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080241"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0080241"
}