{
    "disease_id": "DOID:0050644",
    "recommended_name": {
        "id": "DOID:0050644",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0050644",
        "name": "arterial calcification of infancy",
        "description": "A vascular disease that is characterized by generalized calcification of the arterial internal elastic lamina, leading to rupture of the lamina and occlusive changes in the tunica intima with stenosis and decreased elasticity of the vessel wall."
    },
    "synonyms": [
        {
            "id": "DOID:0050644",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0050644",
            "name": "generalized arterial calcification of infancy",
            "description": ""
        },
        {
            "id": "DOID:0050644",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0050644",
            "name": "idiopathic infantile arterial calcification",
            "description": ""
        },
        {
            "id": "DOID:0050644",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0050644",
            "name": "infantile arteriosclerosis",
            "description": ""
        },
        {
            "id": "MONDO:0008817",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008817",
            "name": "arterial calcification, generalized, of infancy, 1",
            "description": "An autosomal recessive genetic disorder caused by mutations in the ENPP1 gene, encoding ectonucleotide pyrophosphatase/phosphodiesterase family member 1. The condition is characterized by calcification and narrowing of medium- and large-sized arteries, resulting in cardiovascular complications."
        },
        {
            "id": "MONDO:0008817",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008817",
            "name": "ENPP1 arterial calcification of infancy",
            "description": ""
        },
        {
            "id": "MONDO:0008817",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008817",
            "name": "arterial calcification of infancy caused by mutation in ENPP1",
            "description": ""
        },
        {
            "id": "MONDO:0008817",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008817",
            "name": "arterial calcification, generalized, of infancy, 1",
            "description": ""
        },
        {
            "id": "MONDO:0008817",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008817",
            "name": "arterial calcification, generalized, of infancy, type 1",
            "description": ""
        },
        {
            "id": "MONDO:0008817",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008817",
            "name": "generalised arterial calcification of infancy 1",
            "description": ""
        },
        {
            "id": "MONDO:0008817",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008817",
            "name": "generalized arterial calcification of infancy 1",
            "description": ""
        },
        {
            "id": "MONDO:0008817",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008817",
            "name": "GACI1",
            "description": ""
        },
        {
            "id": "MONDO:0013768",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013768",
            "name": "arterial calcification, generalized, of infancy, 2",
            "description": "Any arterial calcification of infancy in which the cause of the disease is a mutation in the ABCC6 gene."
        },
        {
            "id": "MONDO:0013768",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013768",
            "name": "ABCC6 arterial calcification of infancy",
            "description": ""
        },
        {
            "id": "MONDO:0013768",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013768",
            "name": "arterial calcification of infancy caused by mutation in ABCC6",
            "description": ""
        },
        {
            "id": "MONDO:0013768",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013768",
            "name": "arterial calcification, generalized, of infancy, 2",
            "description": ""
        },
        {
            "id": "MONDO:0013768",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013768",
            "name": "arterial calcification, generalized, of infancy, type 2",
            "description": ""
        },
        {
            "id": "MONDO:0013768",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013768",
            "name": "GACI2",
            "description": ""
        },
        {
            "id": "MIM:208000",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/208000",
            "name": "Arterial calcification of infancy, generalized, 1",
            "description": "Arterial calcification of infancy, generalized, 1"
        },
        {
            "id": "MIM:614473",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/614473",
            "name": "Arterial calcification of infancy, generalized, 2",
            "description": "Arterial calcification of infancy, generalized, 2"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0050644"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0050644",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0050644",
            "categories": []
        },
        {
            "id": "MONDO:0008817",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008817",
            "categories": []
        },
        {
            "id": "MONDO:0013768",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013768",
            "categories": []
        },
        {
            "id": "MIM:208000",
            "database": "MIM",
            "url": "https://www.omim.org/entry/208000",
            "categories": []
        },
        {
            "id": "MIM:614473",
            "database": "MIM",
            "url": "https://www.omim.org/entry/614473",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "E7F118-1",
            "uniprot_ac": "E7F118",
            "uniprot_id": "E7F118_DANRE",
            "refseq_ac": "XP_009300481",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "ABC-type glutathione-S-conjugate transporter",
                    "type": "recommended"
                },
                {
                    "name": "7.6.2.3",
                    "type": "synonym"
                },
                {
                    "name": "multidrug resistance-associated protein 1 isoform X1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "abcc6a",
                    "type": "recommended"
                },
                {
                    "name": "abcc6a",
                    "type": "synonym"
                }
            ],
            "record_id": "E7F118-1",
            "evidence": [
                {
                    "id": "0050644",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050644"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A140LGU2-1",
            "uniprot_ac": "A0A140LGU2",
            "uniprot_id": "A0A140LGU2_DANRE",
            "refseq_ac": "XP_003198194",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "ABC-type glutathione-S-conjugate transporter",
                    "type": "recommended"
                },
                {
                    "name": "7.6.2.3",
                    "type": "synonym"
                },
                {
                    "name": "multidrug resistance-associated protein 1 isoform X1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "abcc6b.2",
                    "type": "recommended"
                },
                {
                    "name": "abcc6b.2",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A140LGU2-1",
            "evidence": [
                {
                    "id": "0050644",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050644"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P06802-1",
            "uniprot_ac": "P06802",
            "uniprot_id": "ENPP1_MOUSE",
            "refseq_ac": "NP_001295256",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 1",
                    "type": "recommended"
                },
                {
                    "name": "3.1.4.1",
                    "type": "synonym"
                },
                {
                    "name": "3.6.1.9",
                    "type": "synonym"
                },
                {
                    "name": "Alkaline phosphodiesterase I",
                    "type": "synonym"
                },
                {
                    "name": "E-NPP 1",
                    "type": "synonym"
                },
                {
                    "name": "Ly-41",
                    "type": "synonym"
                },
                {
                    "name": "Lymphocyte antigen 41",
                    "type": "synonym"
                },
                {
                    "name": "NPPase",
                    "type": "synonym"
                },
                {
                    "name": "Nucleotide diphosphatase",
                    "type": "synonym"
                },
                {
                    "name": "Nucleotide pyrophosphatase",
                    "type": "synonym"
                },
                {
                    "name": "Phosphodiesterase I/nucleotide pyrophosphatase 1",
                    "type": "synonym"
                },
                {
                    "name": "Plasma-cell membrane glycoprotein PC-1",
                    "type": "synonym"
                },
                {
                    "name": "alkaline phosphodiesterase I",
                    "type": "synonym"
                },
                {
                    "name": "ectonucleotide pyrophosphatase/phosphodiesterase family member 1 isoform 1",
                    "type": "synonym"
                },
                {
                    "name": "ectonucleotide pyrophosphatase/phosphodiesterase family member 1",
                    "type": "synonym"
                },
                {
                    "name": "lymphocyte antigen 41",
                    "type": "synonym"
                },
                {
                    "name": "nucleotide diphosphatase",
                    "type": "synonym"
                },
                {
                    "name": "phosphodiesterase I/nucleotide pyrophosphatase 1",
                    "type": "synonym"
                },
                {
                    "name": "plasma-cell membrane glycoprotein PC-1",
                    "type": "synonym"
                },
                {
                    "name": "tiptoe walking",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Enpp1",
                    "type": "recommended"
                },
                {
                    "name": "4833416E15Rik",
                    "type": "synonym"
                },
                {
                    "name": "CD203c",
                    "type": "synonym"
                },
                {
                    "name": "E-NPP 1",
                    "type": "synonym"
                },
                {
                    "name": "E-NPP1",
                    "type": "synonym"
                },
                {
                    "name": "Enpp1",
                    "type": "synonym"
                },
                {
                    "name": "Ly-41",
                    "type": "synonym"
                },
                {
                    "name": "M6S1",
                    "type": "synonym"
                },
                {
                    "name": "NPP1",
                    "type": "synonym"
                },
                {
                    "name": "Npps",
                    "type": "synonym"
                },
                {
                    "name": "PC-1",
                    "type": "synonym"
                },
                {
                    "name": "Pc1",
                    "type": "synonym"
                },
                {
                    "name": "Pca-1",
                    "type": "synonym"
                },
                {
                    "name": "Pca",
                    "type": "synonym"
                },
                {
                    "name": "Pdnp1",
                    "type": "synonym"
                },
                {
                    "name": "ttw",
                    "type": "synonym"
                },
                {
                    "name": "twy",
                    "type": "synonym"
                }
            ],
            "record_id": "P06802-1",
            "evidence": [
                {
                    "id": "0050644",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050644"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9R1S7-1",
            "uniprot_ac": "Q9R1S7",
            "uniprot_id": "MRP6_MOUSE",
            "refseq_ac": "NP_061265",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "ATP-binding cassette sub-family C member 6",
                    "type": "recommended"
                },
                {
                    "name": "7.6.2.-",
                    "type": "synonym"
                },
                {
                    "name": "7.6.2.3",
                    "type": "synonym"
                },
                {
                    "name": "ATP-binding cassette sub-family C member 6",
                    "type": "synonym"
                },
                {
                    "name": "ATP-binding cassette, sub-family C (CFTR/MRP), member 6",
                    "type": "synonym"
                },
                {
                    "name": "Multidrug resistance-associated protein 6",
                    "type": "synonym"
                },
                {
                    "name": "multidrug resistance-associated protein 6",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Abcc6",
                    "type": "recommended"
                },
                {
                    "name": "Abcc1b",
                    "type": "synonym"
                },
                {
                    "name": "Abcc6",
                    "type": "synonym"
                },
                {
                    "name": "DCC",
                    "type": "synonym"
                },
                {
                    "name": "Dyscalc1",
                    "type": "synonym"
                },
                {
                    "name": "Mrp6",
                    "type": "synonym"
                },
                {
                    "name": "dyscalc",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9R1S7-1",
            "evidence": [
                {
                    "id": "0050644",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050644"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "O95255-1",
            "uniprot_ac": "O95255",
            "uniprot_id": "MRP6_HUMAN",
            "refseq_ac": "NP_001072996",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "ATP-binding cassette sub-family C member 6",
                    "type": "recommended"
                },
                {
                    "name": "7.6.2.-",
                    "type": "synonym"
                },
                {
                    "name": "7.6.2.3",
                    "type": "synonym"
                },
                {
                    "name": "ATP-binding cassette, sub-family C (CFTR/MRP), member 6",
                    "type": "synonym"
                },
                {
                    "name": "Anthracycline resistance-associated protein",
                    "type": "synonym"
                },
                {
                    "name": "MOAT-E",
                    "type": "synonym"
                },
                {
                    "name": "Multi-specific organic anion transporter E",
                    "type": "synonym"
                },
                {
                    "name": "Multidrug resistance-associated protein 6",
                    "type": "synonym"
                },
                {
                    "name": "URG7 protein isoform 2",
                    "type": "synonym"
                },
                {
                    "name": "anthracycline resistance-associated protein",
                    "type": "synonym"
                },
                {
                    "name": "multi-specific organic anion transporter E",
                    "type": "synonym"
                },
                {
                    "name": "multidrug resistance-associated protein 6",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "ABCC6",
                    "type": "recommended"
                },
                {
                    "name": "ABC34",
                    "type": "synonym"
                },
                {
                    "name": "ABCC6",
                    "type": "synonym"
                },
                {
                    "name": "ARA",
                    "type": "synonym"
                },
                {
                    "name": "EST349056",
                    "type": "synonym"
                },
                {
                    "name": "GACI2",
                    "type": "synonym"
                },
                {
                    "name": "MLP1",
                    "type": "synonym"
                },
                {
                    "name": "MOAT-E",
                    "type": "synonym"
                },
                {
                    "name": "MOATE",
                    "type": "synonym"
                },
                {
                    "name": "MRP6",
                    "type": "synonym"
                },
                {
                    "name": "PXE1",
                    "type": "synonym"
                },
                {
                    "name": "PXE",
                    "type": "synonym"
                },
                {
                    "name": "URG7",
                    "type": "synonym"
                }
            ],
            "record_id": "O95255-1",
            "evidence": [
                {
                    "id": "614473",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/614473"
                },
                {
                    "id": "0050644",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050644"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P22413-1",
            "uniprot_ac": "P22413",
            "uniprot_id": "ENPP1_HUMAN",
            "refseq_ac": "NP_006199",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 1",
                    "type": "recommended"
                },
                {
                    "name": "3.1.4.1",
                    "type": "synonym"
                },
                {
                    "name": "3.6.1.9",
                    "type": "synonym"
                },
                {
                    "name": "Alkaline phosphodiesterase I",
                    "type": "synonym"
                },
                {
                    "name": "E-NPP 1",
                    "type": "synonym"
                },
                {
                    "name": "Ly-41 antigen",
                    "type": "synonym"
                },
                {
                    "name": "Membrane component chromosome 6 surface marker 1",
                    "type": "synonym"
                },
                {
                    "name": "NPPase",
                    "type": "synonym"
                },
                {
                    "name": "Nucleotide diphosphatase",
                    "type": "synonym"
                },
                {
                    "name": "Nucleotide pyrophosphatase",
                    "type": "synonym"
                },
                {
                    "name": "Phosphodiesterase I/nucleotide pyrophosphatase 1",
                    "type": "synonym"
                },
                {
                    "name": "Plasma-cell membrane glycoprotein PC-1",
                    "type": "synonym"
                },
                {
                    "name": "alkaline phosphodiesterase 1",
                    "type": "synonym"
                },
                {
                    "name": "alkaline phosphodiesterase I",
                    "type": "synonym"
                },
                {
                    "name": "ectonucleotide pyrophosphatase/phosphodiesterase family member 1",
                    "type": "synonym"
                },
                {
                    "name": "membrane component, chromosome 6, surface marker 1",
                    "type": "synonym"
                },
                {
                    "name": "nucleotide diphosphatase",
                    "type": "synonym"
                },
                {
                    "name": "phosphodiesterase I/nucleotide pyrophosphatase 1",
                    "type": "synonym"
                },
                {
                    "name": "plasma-cell membrane glycoprotein 1",
                    "type": "synonym"
                },
                {
                    "name": "plasma-cell membrane glycoprotein PC-1",
                    "type": "synonym"
                }
            ],
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                {
                    "name": "ENPP1",
                    "type": "recommended"
                },
                {
                    "name": "ARHR2",
                    "type": "synonym"
                },
                {
                    "name": "COLED",
                    "type": "synonym"
                },
                {
                    "name": "ENPP1",
                    "type": "synonym"
                },
                {
                    "name": "M6S1",
                    "type": "synonym"
                },
                {
                    "name": "NPP1",
                    "type": "synonym"
                },
                {
                    "name": "NPPS",
                    "type": "synonym"
                },
                {
                    "name": "PC-1",
                    "type": "synonym"
                },
                {
                    "name": "PC1",
                    "type": "synonym"
                },
                {
                    "name": "PCA1",
                    "type": "synonym"
                },
                {
                    "name": "PDNP1",
                    "type": "synonym"
                }
            ],
            "record_id": "P22413-1",
            "evidence": [
                {
                    "id": "208000",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/208000"
                },
                {
                    "id": "0050644",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050644"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P14772-1",
            "uniprot_ac": "P14772",
            "uniprot_id": "BPT1_YEAST",
            "refseq_ac": "NP_013086",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Saccharomyces cerevisiae S288C",
                    "taxid": 559292,
                    "common_name": "Baker's yeast",
                    "glygen_name": "Yeast",
                    "reference_species": "Saccharomyces cerevisiae S288C [559292]"
                }
            ],
            "protein_names": [
                {
                    "name": "Bile pigment transporter 1",
                    "type": "recommended"
                },
                {
                    "name": "ATP-binding cassette bilirubin transporter BPT1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "BPT1",
                    "type": "recommended"
                },
                {
                    "name": "BPT1",
                    "type": "synonym"
                },
                {
                    "name": "L1313",
                    "type": "synonym"
                }
            ],
            "record_id": "P14772-1",
            "evidence": [
                {
                    "id": "0050644",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050644"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P39109-1",
            "uniprot_ac": "P39109",
            "uniprot_id": "YCFI_YEAST",
            "refseq_ac": "NP_010419",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Saccharomyces cerevisiae S288C",
                    "taxid": 559292,
                    "common_name": "Baker's yeast",
                    "glygen_name": "Yeast",
                    "reference_species": "Saccharomyces cerevisiae S288C [559292]"
                }
            ],
            "protein_names": [
                {
                    "name": "Metal resistance protein YCF1",
                    "type": "recommended"
                },
                {
                    "name": "7.2.2.2",
                    "type": "synonym"
                },
                {
                    "name": "7.6.2.3",
                    "type": "synonym"
                },
                {
                    "name": "ABC-type Cd(2+) transporter",
                    "type": "synonym"
                },
                {
                    "name": "ABC-type glutathione-S-conjugate transporter",
                    "type": "synonym"
                },
                {
                    "name": "ATP-binding cassette glutathione S-conjugate transporter YCF1",
                    "type": "synonym"
                },
                {
                    "name": "Yeast cadmium factor 1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "YCF1",
                    "type": "recommended"
                },
                {
                    "name": "YCF1",
                    "type": "synonym"
                },
                {
                    "name": "YD9302.11C",
                    "type": "synonym"
                }
            ],
            "record_id": "P39109-1",
            "evidence": [
                {
                    "id": "0050644",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050644"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P39997-1",
            "uniprot_ac": "P39997",
            "uniprot_id": "NPP2_YEAST",
            "refseq_ac": "NP_010900",
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                {
                    "name": "Saccharomyces cerevisiae S288C",
                    "taxid": 559292,
                    "common_name": "Baker's yeast",
                    "glygen_name": "Yeast",
                    "reference_species": "Saccharomyces cerevisiae S288C [559292]"
                }
            ],
            "protein_names": [
                {
                    "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 2",
                    "type": "recommended"
                },
                {
                    "name": "E-NPP 2",
                    "type": "synonym"
                },
                {
                    "name": "Nucleotide diphosphatase",
                    "type": "synonym"
                },
                {
                    "name": "nucleotide diphosphatase/phosphodiesterase NPP2",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "NPP2",
                    "type": "recommended"
                },
                {
                    "name": "NPP2",
                    "type": "synonym"
                }
            ],
            "record_id": "P39997-1",
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                {
                    "id": "0050644",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050644"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P25353-1",
            "uniprot_ac": "P25353",
            "uniprot_id": "NPP1_YEAST",
            "refseq_ac": "NP_009955",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Saccharomyces cerevisiae S288C",
                    "taxid": 559292,
                    "common_name": "Baker's yeast",
                    "glygen_name": "Yeast",
                    "reference_species": "Saccharomyces cerevisiae S288C [559292]"
                }
            ],
            "protein_names": [
                {
                    "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 1",
                    "type": "recommended"
                },
                {
                    "name": "E-NPP 1",
                    "type": "synonym"
                },
                {
                    "name": "Nucleotide diphosphatase",
                    "type": "synonym"
                },
                {
                    "name": "nucleotide diphosphatase/phosphodiesterase NPP1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "NPP1",
                    "type": "recommended"
                },
                {
                    "name": "NPP1",
                    "type": "synonym"
                },
                {
                    "name": "YCR246",
                    "type": "synonym"
                },
                {
                    "name": "YCR26C",
                    "type": "synonym"
                }
            ],
            "record_id": "P25353-1",
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                {
                    "id": "0050644",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050644"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "O88269-1",
            "uniprot_ac": "O88269",
            "uniprot_id": "MRP6_RAT",
            "refseq_ac": "NP_112275",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "ATP-binding cassette sub-family C member 6",
                    "type": "recommended"
                },
                {
                    "name": "7.6.2.-",
                    "type": "synonym"
                },
                {
                    "name": "7.6.2.3",
                    "type": "synonym"
                },
                {
                    "name": "ATP-binding cassette sub-family C member 6",
                    "type": "synonym"
                },
                {
                    "name": "ATP-binding cassette, sub-family C (CFTR/MRP), member 6",
                    "type": "synonym"
                },
                {
                    "name": "ATP-binding cassette, subfamily C (CFTR/MRP), member 6",
                    "type": "synonym"
                },
                {
                    "name": "MLP-1",
                    "type": "synonym"
                },
                {
                    "name": "MRP-like protein 1",
                    "type": "synonym"
                },
                {
                    "name": "Multidrug resistance-associated protein 6",
                    "type": "synonym"
                },
                {
                    "name": "liver multidrug resistance-associated protein 6",
                    "type": "synonym"
                },
                {
                    "name": "multidrug resistance-associated protein 6",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Abcc6",
                    "type": "recommended"
                },
                {
                    "name": "Abcc6",
                    "type": "synonym"
                },
                {
                    "name": "Mlp1",
                    "type": "synonym"
                },
                {
                    "name": "Mrp6",
                    "type": "synonym"
                }
            ],
            "record_id": "O88269-1",
            "evidence": [
                {
                    "id": "0050644",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050644"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q924C3-1",
            "uniprot_ac": "Q924C3",
            "uniprot_id": "ENPP1_RAT",
            "refseq_ac": "NP_445987",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 1",
                    "type": "recommended"
                },
                {
                    "name": "3.1.4.1",
                    "type": "synonym"
                },
                {
                    "name": "3.6.1.9",
                    "type": "synonym"
                },
                {
                    "name": "Alkaline phosphodiesterase I",
                    "type": "synonym"
                },
                {
                    "name": "E-NPP 1",
                    "type": "synonym"
                },
                {
                    "name": "NPPase",
                    "type": "synonym"
                },
                {
                    "name": "Nucleotide diphosphatase",
                    "type": "synonym"
                },
                {
                    "name": "Nucleotide pyrophosphatase",
                    "type": "synonym"
                },
                {
                    "name": "Phosphodiesterase I/nucleotide pyrophosphatase 1",
                    "type": "synonym"
                },
                {
                    "name": "Plasma-cell membrane glycoprotein PC-1",
                    "type": "synonym"
                },
                {
                    "name": "alkaline phosphodiesterase I",
                    "type": "synonym"
                },
                {
                    "name": "ectonucleotide pyrophosphatase/phosphodiesterase family member 1",
                    "type": "synonym"
                },
                {
                    "name": "nucleotide diphosphatase",
                    "type": "synonym"
                },
                {
                    "name": "phosphodiesterase I/nucleotide pyrophosphatase 1",
                    "type": "synonym"
                },
                {
                    "name": "plasma-cell membrane glycoprotein PC-1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Enpp1",
                    "type": "recommended"
                },
                {
                    "name": "Enpp1",
                    "type": "synonym"
                },
                {
                    "name": "Npps",
                    "type": "synonym"
                },
                {
                    "name": "Pc1",
                    "type": "synonym"
                },
                {
                    "name": "Pdnp1",
                    "type": "synonym"
                }
            ],
            "record_id": "Q924C3-1",
            "evidence": [
                {
                    "id": "0050644",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050644"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0050644"
}