{
    "disease_id": "DOID:0050636",
    "recommended_name": {
        "id": "DOID:0050636",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0050636",
        "name": "hereditary systemic amyloidosis 2",
        "description": "An amyloidosis that is characterized by the abnormal deposition of amyloid proteins that is located_in the visceral organs, primarily the kidneys."
    },
    "synonyms": [
        {
            "id": "DOID:0050636",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0050636",
            "name": "AMYLOIDOSIS, FAMILIAL RENAL",
            "description": ""
        },
        {
            "id": "DOID:0050636",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0050636",
            "name": "German type amyloidosis",
            "description": ""
        },
        {
            "id": "DOID:0050636",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0050636",
            "name": "OSTERTAG TYPE AMYLOIDOSIS",
            "description": ""
        },
        {
            "id": "DOID:0050636",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0050636",
            "name": "systemic nonneuropathic amyloidosis",
            "description": ""
        },
        {
            "id": "DOID:0050636",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0050636",
            "name": "familial visceral amyloidosis",
            "description": ""
        },
        {
            "id": "MONDO:0007099",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007099",
            "name": "familial visceral amyloidosis",
            "description": ""
        },
        {
            "id": "MONDO:0007099",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007099",
            "name": "German type amyloidosis",
            "description": ""
        },
        {
            "id": "MONDO:0007099",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007099",
            "name": "Ostertag type amyloidosis",
            "description": ""
        },
        {
            "id": "MONDO:0007099",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007099",
            "name": "amyloidosis, 3 or more types",
            "description": ""
        },
        {
            "id": "MONDO:0007099",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007099",
            "name": "amyloidosis, Ostertag type",
            "description": ""
        },
        {
            "id": "MONDO:0007099",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007099",
            "name": "amyloidosis, familial renal",
            "description": ""
        },
        {
            "id": "MONDO:0007099",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007099",
            "name": "amyloidosis, renal",
            "description": ""
        },
        {
            "id": "MONDO:0007099",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007099",
            "name": "familial amyloid nephropathy",
            "description": ""
        },
        {
            "id": "MONDO:0007099",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007099",
            "name": "familial renal amyloidosis",
            "description": ""
        },
        {
            "id": "MONDO:0007099",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007099",
            "name": "hereditary amyloid nephropathy",
            "description": ""
        },
        {
            "id": "MONDO:0007099",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007099",
            "name": "hereditary renal amyloidosis",
            "description": ""
        },
        {
            "id": "MONDO:0007099",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007099",
            "name": "amyloidosis VIII",
            "description": ""
        },
        {
            "id": "MONDO:0007099",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007099",
            "name": "amyloidosis familial renal",
            "description": ""
        },
        {
            "id": "MONDO:0007099",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007099",
            "name": "amyloidosis familial visceral",
            "description": ""
        },
        {
            "id": "MONDO:0007099",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007099",
            "name": "amyloidosis systemic nonneuropathic",
            "description": ""
        },
        {
            "id": "MONDO:0007099",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007099",
            "name": "hereditary amyloidosis with primary renal involement",
            "description": ""
        },
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            "id": "MIM:105200",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/105200",
            "name": "Amyloidosis, hereditary systemic 2",
            "description": "Amyloidosis, hereditary systemic 2"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0050636"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0050636",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0050636",
            "categories": []
        },
        {
            "id": "MONDO:0007099",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007099",
            "categories": []
        },
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            "id": "MIM:105200",
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            "url": "https://www.omim.org/entry/105200",
            "categories": []
        }
    ],
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            "uniprot_canonical_ac": "B8A5L6-1",
            "uniprot_ac": "B8A5L6",
            "uniprot_id": "B8A5L6_DANRE",
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            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
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                {
                    "name": "Fibrinogen alpha chain precursor",
                    "type": "synonym"
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                {
                    "name": "fibrinogen alpha chain precursor",
                    "type": "synonym"
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                    "type": "recommended"
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                {
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                },
                {
                    "name": "sb:cb892",
                    "type": "synonym"
                },
                {
                    "name": "wu:fa55c12",
                    "type": "synonym"
                },
                {
                    "name": "wu:fb20e08",
                    "type": "synonym"
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                    "name": "wu:fb59b03",
                    "type": "synonym"
                },
                {
                    "name": "wu:fi39d04",
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                {
                    "name": "zgc:92117",
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                    "id": "0050636",
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        },
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            "uniprot_ac": "E9PV24",
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            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
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                {
                    "name": "Fibrinogen alpha chain",
                    "type": "recommended"
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                {
                    "name": "fibrinogen alpha chain isoform 1 preproprotein",
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                {
                    "name": "fibrinogen, A alpha polypeptide",
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            ],
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                    "type": "recommended"
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                {
                    "name": "Fga",
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                },
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                    "name": "Fib",
                    "type": "synonym"
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        },
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            "uniprot_ac": "P02671",
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            "refseq_ac": "NP_000499",
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                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
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                {
                    "name": "Fibrinogen alpha chain",
                    "type": "recommended"
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                {
                    "name": "fibrinogen alpha chain isoform alpha-E preproprotein",
                    "type": "synonym"
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                {
                    "name": "fibrinogen, A alpha polypeptide",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "FGA",
                    "type": "recommended"
                },
                {
                    "name": "AMYLD2",
                    "type": "synonym"
                },
                {
                    "name": "FGA",
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                {
                    "name": "Fib2",
                    "type": "synonym"
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            ],
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                    "id": "0050636",
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                    "url": "https://www.alliancegenome.org/disease/DOID:0050636"
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            "uniprot_ac": "P06399",
            "uniprot_id": "FIBA_RAT",
            "refseq_ac": "",
            "glycoprotein": "yes",
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                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
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                {
                    "name": "Fibrinogen alpha chain",
                    "type": "recommended"
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            ],
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                {
                    "name": "Fga",
                    "type": "recommended"
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                    "url": "https://www.alliancegenome.org/disease/DOID:0050636"
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            "uniprot_canonical_ac": "P63301-1",
            "uniprot_ac": "P63301",
            "uniprot_id": "SELW_RAT",
            "refseq_ac": "NP_037159",
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                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
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                {
                    "name": "Selenoprotein W",
                    "type": "recommended"
                },
                {
                    "name": "SelW",
                    "type": "synonym"
                },
                {
                    "name": "selenoprotein W, 1",
                    "type": "synonym"
                },
                {
                    "name": "selenoprotein W, muscle 1",
                    "type": "synonym"
                },
                {
                    "name": "selenoprotein W",
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                }
            ],
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                    "name": "Selenow",
                    "type": "recommended"
                },
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                    "name": "SelW",
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                },
                {
                    "name": "Selenow",
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                },
                {
                    "name": "Selw",
                    "type": "synonym"
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                {
                    "name": "Sepw1",
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                    "id": "0050636",
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        },
        {
            "uniprot_canonical_ac": "O43174-1",
            "uniprot_ac": "O43174",
            "uniprot_id": "CP26A_HUMAN",
            "refseq_ac": "NP_000774",
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                {
                    "name": "Homo sapiens",
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                    "common_name": "Human",
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                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Cytochrome P450 26A1",
                    "type": "recommended"
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                {
                    "name": "1.14.13.-",
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                    "name": "CYP26A1",
                    "type": "synonym"
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                {
                    "name": "Cytochrome P450 retinoic acid-inactivating 1",
                    "type": "synonym"
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                {
                    "name": "Cytochrome P450RAI",
                    "type": "synonym"
                },
                {
                    "name": "P450, retinoic acid-inactivating, 1",
                    "type": "synonym"
                },
                {
                    "name": "Retinoic acid 4-hydroxylase",
                    "type": "synonym"
                },
                {
                    "name": "Retinoic acid-metabolizing cytochrome",
                    "type": "synonym"
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                    "name": "cytochrome P450 26A1 isoform 1",
                    "type": "synonym"
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                    "name": "cytochrome P450 26A1",
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                {
                    "name": "cytochrome P450 retinoic acid-inactivating 1",
                    "type": "synonym"
                },
                {
                    "name": "cytochrome P450, family 26, subfamily A, polypeptide 1",
                    "type": "synonym"
                },
                {
                    "name": "cytochrome P450, subfamily XXVIA, polypeptide 1",
                    "type": "synonym"
                },
                {
                    "name": "cytochrome P450RAI",
                    "type": "synonym"
                },
                {
                    "name": "hP450RAI",
                    "type": "synonym"
                },
                {
                    "name": "retinoic acid 4-hydroxylase",
                    "type": "synonym"
                },
                {
                    "name": "retinoic acid-metabolizing cytochrome",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "CYP26A1",
                    "type": "recommended"
                },
                {
                    "name": "CP26",
                    "type": "synonym"
                },
                {
                    "name": "CYP26A1",
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                },
                {
                    "name": "CYP26",
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                },
                {
                    "name": "P450RAI1",
                    "type": "synonym"
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                {
                    "name": "P450RAI",
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                    "id": "0050636",
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                    "url": "https://www.alliancegenome.org/disease/DOID:0050636"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0050636"
}