{
    "biomarker_id": "BB3865-4",
    "biomarker_canonical_id": "BB3865",
    "condition": {
        "recommended_name": {
            "id": "DOID:9191",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:9191",
            "name": "diabetic macular edema",
            "description": ""
        },
        "synonyms": [],
        "id": "DOID:9191"
    },
    "biomarker_component": [
        {
            "biomarker": "decreased level of G1FN on immunoglobulin G",
            "assessed_biomarker_entity_id": "P01825-1",
            "assessed_entity_type": "protein",
            "assessed_biomarker_entity": {
                "recommended_name": "Immunoglobulin heavy variable 4-59",
                "synonyms": [
                    {
                        "synonym": "Ig heavy chain V-II region NEWM"
                    }
                ]
            },
            "specimen": [
                {
                    "name": "blood serum",
                    "namespace": "UBERON",
                    "id": "0001977",
                    "url": "http://purl.obolibrary.org/obo/UBERON_0001977",
                    "loinc_code": ""
                }
            ],
            "evidence_source": [
                {
                    "id": "BB3865-4",
                    "database": "BiomarkerKB",
                    "url": "https://biomarkerkb.org/biomarker/BB3865-4"
                },
                {
                    "id": "40204274",
                    "database": "PubMed",
                    "url": "",
                    "tags": [
                        "assessed_biomarker_entity_id",
                        " assessed_biomarker_entiy",
                        " assessed_entity_type",
                        " biomarker",
                        " specimen"
                    ],
                    "evidence_list": [
                        {
                            "evidence": "Analysis using the Mann-Whitney U test revealed that DSIgG1: G2F/G1F; DSIgG2: G1FN/G0FN, G2F/G0F, and G2F/G1F were significantly lower in the DME(+) group compared to the DME(\u2212) group as shown in Figure 3. Lastly, Combined Biomarker 4 consists of nine DSIgG N-glycopeptide ratios (AUC = 0.7846, sensitivity = 70.59%, specificity = 75.56%) and performed superbly in identifying the presence of DME in patients."
                        }
                    ]
                }
            ]
        }
    ],
    "best_biomarker_role": [
        {
            "role": ""
        }
    ],
    "evidence_source": [
        {
            "id": "BB3865-4",
            "database": "BiomarkerKB",
            "url": "https://biomarkerkb.org/biomarker/BB3865-4"
        },
        {
            "id": "40204274",
            "database": "PubMed",
            "url": "",
            "tags": [
                "condition"
            ],
            "evidence_list": [
                {
                    "evidence": "Analysis using the Mann-Whitney U test revealed that DSIgG1: G2F/G1F; DSIgG2: G1FN/G0FN, G2F/G0F, and G2F/G1F were significantly lower in the DME(+) group compared to the DME(\u2212) group as shown in Figure 3. Lastly, Combined Biomarker 4 consists of nine DSIgG N-glycopeptide ratios (AUC = 0.7846, sensitivity = 70.59%, specificity = 75.56%) and performed superbly in identifying the presence of DME in patients."
                }
            ]
        }
    ],
    "crossref": [
        {
            "id": "BB3865-4",
            "database": "BiomarkerKB",
            "url": "https://biomarkerkb.org/biomarker/BB3865-4",
            "categories": [
                "Biomarkers"
            ]
        }
    ],
    "citation": [],
    "section_stats": [
        {
            "table_id": "biomarker_component",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                }
            ],
            "sort_fields": [
                "biomarker",
                "assessed_biomarker_entity_id",
                "assessed_entity_type",
                "assessed_biomarker_entity.recommended_name"
            ]
        },
        {
            "table_id": "citation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                }
            ],
            "sort_fields": []
        }
    ]
}