{
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    "biomarker_canonical_id": "BB1479",
    "condition": {
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            },
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            },
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            },
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            },
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            },
            {
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            },
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            },
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                "description": ""
            },
            {
                "id": "MONDO:0005575",
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                "description": ""
            },
            {
                "id": "MONDO:0005575",
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                "name": "colorectal cancer, susceptibility to, autosomal dominant, somatic mutation",
                "description": ""
            },
            {
                "id": "MONDO:0005575",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0005575",
                "name": "colorectum cancer",
                "description": ""
            },
            {
                "id": "MONDO:0005575",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0005575",
                "name": "malignant colorectal neoplasm",
                "description": ""
            },
            {
                "id": "MONDO:0005575",
                "resource": "MONDO",
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                "name": "malignant colorectal tumor",
                "description": ""
            },
            {
                "id": "MONDO:0005575",
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                "name": "malignant colorectal tumour",
                "description": ""
            },
            {
                "id": "MONDO:0005575",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0005575",
                "name": "malignant colorectum neoplasm",
                "description": ""
            },
            {
                "id": "MONDO:0005575",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0005575",
                "name": "malignant large bowel neoplasm",
                "description": ""
            },
            {
                "id": "MONDO:0005575",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0005575",
                "name": "malignant large bowel tumor",
                "description": ""
            },
            {
                "id": "MONDO:0005575",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0005575",
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                "description": ""
            },
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                "url": "https://monarchinitiative.org/disease/MONDO:0005575",
                "name": "malignant large intestine neoplasm",
                "description": ""
            },
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                "description": ""
            },
            {
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                "description": ""
            },
            {
                "id": "MONDO:0005575",
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                "url": "https://monarchinitiative.org/disease/MONDO:0005575",
                "name": "malignant neoplasm of colorectum",
                "description": ""
            },
            {
                "id": "MONDO:0005575",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0005575",
                "name": "malignant neoplasm of large bowel",
                "description": ""
            },
            {
                "id": "MONDO:0005575",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0005575",
                "name": "malignant neoplasm of large intestine",
                "description": ""
            },
            {
                "id": "MONDO:0005575",
                "resource": "MONDO",
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                "name": "malignant neoplasm of the large bowel",
                "description": ""
            },
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                "description": ""
            },
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                "name": "malignant tumour of large bowel",
                "description": ""
            },
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                "name": "malignant tumour of large intestine",
                "description": ""
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                "name": "malignant tumour of the large bowel",
                "description": ""
            },
            {
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                "resource": "MONDO",
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                "name": "malignant tumour of the large intestine",
                "description": ""
            },
            {
                "id": "MONDO:0005575",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0005575",
                "name": "CRC",
                "description": ""
            },
            {
                "id": "MIM:114500",
                "resource": "MIM",
                "url": "https://www.omim.org/entry/114500",
                "name": "Colorectal cancer",
                "description": "Colorectal cancer"
            }
        ],
        "id": "DOID:9256"
    },
    "biomarker_component": [
        {
            "biomarker": "decreased levels of UBX2A",
            "assessed_biomarker_entity_id": "P68543-1",
            "assessed_entity_type": "protein",
            "assessed_biomarker_entity": {
                "recommended_name": "UBX domain-containing protein 2A",
                "synonyms": [
                    {
                        "synonym": "UBX domain-containing protein 4"
                    }
                ]
            },
            "specimen": [
                {
                    "name": "blood",
                    "namespace": "UBERON",
                    "id": "0000178",
                    "url": "http://purl.obolibrary.org/obo/UBERON_0000178",
                    "loinc_code": ""
                }
            ],
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                    "database": "BiomarkerKB",
                    "url": "https://biomarkerkb.org/biomarker/BB1479-1"
                },
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                    "tags": [
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                        " assessed_biomarker_entiy",
                        " assessed_entity_type",
                        " biomarker",
                        " specimen"
                    ],
                    "evidence_list": [
                        {
                            "evidence": ""
                        }
                    ]
                }
            ]
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    ],
    "best_biomarker_role": [
        {
            "role": "risk"
        }
    ],
    "evidence_source": [
        {
            "id": "BB1479-1",
            "database": "BiomarkerKB",
            "url": "https://biomarkerkb.org/biomarker/BB1479-1"
        },
        {
            "id": "37037900",
            "database": "PubMed",
            "url": "https://glygen.org/publication/PubMed/37037900",
            "tags": [
                "condition"
            ],
            "evidence_list": [
                {
                    "evidence": ""
                }
            ]
        }
    ],
    "crossref": [
        {
            "id": "BB1479-1",
            "database": "BiomarkerKB",
            "url": "https://biomarkerkb.org/biomarker/BB1479-1",
            "categories": [
                "Biomarkers"
            ]
        }
    ],
    "citation": [
        {
            "title": "UBXN2A suppresses the Rictor-mTORC2 signaling pathway, an established tumorigenic pathway in human colorectal cancer.",
            "journal": "Oncogene",
            "authors": "Sane Sanam, Srinivasan Rekha, Potts Rashaun A, Eikanger Morgan, Zagirova Diana, Freeling Jessica, Reihe Casey A, Antony Ryan M, Gupta Brij K, Lynch Douglas, Bleeker Jonathan, Turaihi Hassan, Pillatzki Angela, Zhou Wei, Luo Xu, Linnebacher Michael, Agany Diing, Zohim Etienne Gnimpieba, Humphrey Lisa E, Black Adrian R, Rezvani Khosrow",
            "date": "2023-04-10",
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                {
                    "type": "PubMed",
                    "id": "37037900",
                    "url": "https://glygen.org/publication/PubMed/37037900"
                }
            ],
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                    "id": "BB1478-1",
                    "database": "BiomarkerKB",
                    "url": "https://biomarkerkb.org/biomarker/BB1479-1"
                }
            ]
        }
    ],
    "section_stats": [
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            "table_id": "biomarker_component",
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            ],
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}