{
    "biomarker_id": "AN6585-1",
    "biomarker_canonical_id": "AN6585",
    "condition": {
        "recommended_name": {
            "id": "DOID:10283",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:10283",
            "name": "prostate cancer",
            "description": "A male reproductive organ cancer that is located_in the prostate."
        },
        "synonyms": [
            {
                "id": "DOID:10283",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:10283",
                "name": "NGP - new growth of prostate",
                "description": ""
            },
            {
                "id": "DOID:10283",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:10283",
                "name": "hereditary prostate cancer",
                "description": ""
            },
            {
                "id": "DOID:10283",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:10283",
                "name": "malignant tumor of the prostate",
                "description": ""
            },
            {
                "id": "DOID:10283",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:10283",
                "name": "prostate cancer, familial",
                "description": ""
            },
            {
                "id": "DOID:10283",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:10283",
                "name": "prostate neoplasm",
                "description": ""
            },
            {
                "id": "DOID:10283",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:10283",
                "name": "prostatic cancer",
                "description": ""
            },
            {
                "id": "DOID:10283",
                "resource": "Disease Ontology",
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                "name": "prostatic neoplasm",
                "description": ""
            },
            {
                "id": "DOID:10283",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:10283",
                "name": "tumor of the prostate",
                "description": ""
            },
            {
                "id": "MONDO:0010257",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0010257",
                "name": "prostate cancer, hereditary, X-linked 1",
                "description": ""
            },
            {
                "id": "MONDO:0010257",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0010257",
                "name": "HPCX1",
                "description": ""
            },
            {
                "id": "MONDO:0010257",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0010257",
                "name": "prostate cancer, hereditary, X-linked 1",
                "description": ""
            },
            {
                "id": "MONDO:0010405",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0010405",
                "name": "prostate cancer, hereditary, X-linked 2",
                "description": ""
            },
            {
                "id": "MONDO:0010405",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0010405",
                "name": "HPCX2",
                "description": ""
            },
            {
                "id": "MONDO:0010405",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0010405",
                "name": "prostate cancer, hereditary, X-linked 2",
                "description": ""
            },
            {
                "id": "MONDO:0011098",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                "name": "prostate cancer, hereditary, 1",
                "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the RNASEL gene."
            },
            {
                "id": "MONDO:0011098",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                "name": "RNASEL familial prostate cancer",
                "description": ""
            },
            {
                "id": "MONDO:0011098",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                "name": "familial prostate cancer caused by mutation in RNASEL",
                "description": ""
            },
            {
                "id": "MONDO:0011098",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                "name": "prostate cancer 1",
                "description": ""
            },
            {
                "id": "MONDO:0011098",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                "name": "prostate cancer, hereditary, 1",
                "description": ""
            },
            {
                "id": "MONDO:0011098",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                "name": "prostate cancer, hereditary, type 1",
                "description": ""
            },
            {
                "id": "MONDO:0011098",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0011098",
                "name": "HPC1",
                "description": ""
            },
            {
                "id": "MONDO:0011270",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0011270",
                "name": "prostate cancer, hereditary, 8",
                "description": ""
            },
            {
                "id": "MONDO:0011270",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0011270",
                "name": "prostate cancer, hereditary, 8",
                "description": ""
            },
            {
                "id": "MONDO:0011270",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0011270",
                "name": "prostate cancer, hereditary, type 8",
                "description": ""
            },
            {
                "id": "MONDO:0011270",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0011270",
                "name": "HPC8",
                "description": ""
            },
            {
                "id": "MONDO:0012093",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012093",
                "name": "prostate cancer, hereditary, 3",
                "description": ""
            },
            {
                "id": "MONDO:0012093",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012093",
                "name": "prostate cancer, hereditary, 3",
                "description": ""
            },
            {
                "id": "MONDO:0012093",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012093",
                "name": "prostate cancer, hereditary, type 3",
                "description": ""
            },
            {
                "id": "MONDO:0012093",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012093",
                "name": "prostate cancer, susceptibility to, 3",
                "description": ""
            },
            {
                "id": "MONDO:0012093",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012093",
                "name": "HPC3",
                "description": ""
            },
            {
                "id": "MONDO:0012094",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                "name": "prostate cancer, hereditary, 4",
                "description": ""
            },
            {
                "id": "MONDO:0012094",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                "name": "prostate cancer, hereditary, 4",
                "description": ""
            },
            {
                "id": "MONDO:0012094",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                "name": "prostate cancer, hereditary, type 4",
                "description": ""
            },
            {
                "id": "MONDO:0012094",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                "name": "prostate cancer, susceptibility to, 4",
                "description": ""
            },
            {
                "id": "MONDO:0012094",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012094",
                "name": "HPC4",
                "description": ""
            },
            {
                "id": "MONDO:0012244",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012244",
                "name": "prostate cancer, hereditary, 5",
                "description": ""
            },
            {
                "id": "MONDO:0012244",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012244",
                "name": "prostate cancer, hereditary, 5",
                "description": ""
            },
            {
                "id": "MONDO:0012244",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012244",
                "name": "prostate cancer, hereditary, type 5",
                "description": ""
            },
            {
                "id": "MONDO:0012244",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012244",
                "name": "HPC5",
                "description": ""
            },
            {
                "id": "MONDO:0012300",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012300",
                "name": "prostate cancer, hereditary, 6",
                "description": ""
            },
            {
                "id": "MONDO:0012300",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012300",
                "name": "prostate cancer, hereditary, 6",
                "description": ""
            },
            {
                "id": "MONDO:0012300",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012300",
                "name": "prostate cancer, hereditary, type 6",
                "description": ""
            },
            {
                "id": "MONDO:0012300",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012300",
                "name": "HPC6",
                "description": ""
            },
            {
                "id": "MONDO:0012470",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012470",
                "name": "prostate cancer, hereditary, 7",
                "description": ""
            },
            {
                "id": "MONDO:0012470",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012470",
                "name": "HPC7",
                "description": ""
            },
            {
                "id": "MONDO:0012470",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012470",
                "name": "prostate cancer, hereditary, 7",
                "description": ""
            },
            {
                "id": "MONDO:0012597",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012597",
                "name": "prostate cancer, hereditary, 9",
                "description": ""
            },
            {
                "id": "MONDO:0012597",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012597",
                "name": "prostate cancer, hereditary, 9",
                "description": ""
            },
            {
                "id": "MONDO:0012597",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012597",
                "name": "prostate cancer, hereditary, type 9",
                "description": ""
            },
            {
                "id": "MONDO:0012597",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012597",
                "name": "HPC9",
                "description": ""
            },
            {
                "id": "MONDO:0012620",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012620",
                "name": "prostate cancer, hereditary, 10",
                "description": ""
            },
            {
                "id": "MONDO:0012620",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012620",
                "name": "HPC10",
                "description": ""
            },
            {
                "id": "MONDO:0012620",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012620",
                "name": "prostate cancer, hereditary, 10",
                "description": ""
            },
            {
                "id": "MONDO:0012741",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                "name": "prostate cancer, hereditary, 12",
                "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the EHBP1 gene."
            },
            {
                "id": "MONDO:0012741",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                "name": "EHBP1 familial prostate cancer",
                "description": ""
            },
            {
                "id": "MONDO:0012741",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                "name": "familial prostate cancer caused by mutation in EHBP1",
                "description": ""
            },
            {
                "id": "MONDO:0012741",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                "name": "prostate cancer, hereditary, 12",
                "description": ""
            },
            {
                "id": "MONDO:0012741",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                "name": "prostate cancer, hereditary, type 12",
                "description": ""
            },
            {
                "id": "MONDO:0012741",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012741",
                "name": "HPC12",
                "description": ""
            },
            {
                "id": "MONDO:0012758",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                "name": "prostate cancer, hereditary, 13",
                "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the MSMB gene."
            },
            {
                "id": "MONDO:0012758",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                "name": "MSMB familial prostate cancer",
                "description": ""
            },
            {
                "id": "MONDO:0012758",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                "name": "familial prostate cancer caused by mutation in MSMB",
                "description": ""
            },
            {
                "id": "MONDO:0012758",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                "name": "prostate cancer, hereditary, 13",
                "description": ""
            },
            {
                "id": "MONDO:0012758",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                "name": "prostate cancer, hereditary, type 13",
                "description": ""
            },
            {
                "id": "MONDO:0012758",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012758",
                "name": "HPC13",
                "description": ""
            },
            {
                "id": "MONDO:0012768",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012768",
                "name": "prostate cancer, hereditary, 11",
                "description": ""
            },
            {
                "id": "MONDO:0012768",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012768",
                "name": "HPC11",
                "description": ""
            },
            {
                "id": "MONDO:0012768",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012768",
                "name": "prostate cancer, hereditary, 11",
                "description": ""
            },
            {
                "id": "MONDO:0012769",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012769",
                "name": "prostate cancer, hereditary, 14",
                "description": ""
            },
            {
                "id": "MONDO:0012769",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012769",
                "name": "HPC14",
                "description": ""
            },
            {
                "id": "MONDO:0012769",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012769",
                "name": "prostate cancer, hereditary, 14",
                "description": ""
            },
            {
                "id": "MONDO:0012770",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012770",
                "name": "prostate cancer, hereditary, 15",
                "description": ""
            },
            {
                "id": "MONDO:0012770",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012770",
                "name": "HPC15",
                "description": ""
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            {
                "id": "MONDO:0012770",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012770",
                "name": "prostate cancer, hereditary, 15",
                "description": ""
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                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0700275",
                "name": "prostate cancer, hereditary",
                "description": "An instance of prostate cancer that is caused by an inherited genomic modification in an individual. Familial prostate cancer (FPC) is a malignant tumor of the prostate with an early onset. FPC is either asymptomatic or causes mictionary symptoms, erectile dysfunction, bone pain, venous compression and infectious or inflammatory syndrome (for the metastatic forms). It is also characterized by familial antecedents."
            },
            {
                "id": "MIM:601518",
                "resource": "MIM",
                "url": "https://www.omim.org/entry/601518",
                "name": "Prostate cancer, hereditary, 1",
                "description": "Prostate cancer, hereditary, 1"
            },
            {
                "id": "MIM:610997",
                "resource": "MIM",
                "url": "https://www.omim.org/entry/610997",
                "name": "Prostate cancer, hereditary, 9",
                "description": "Prostate cancer, hereditary, 9"
            },
            {
                "id": "MIM:611868",
                "resource": "MIM",
                "url": "https://www.omim.org/entry/611868",
                "name": "Prostate cancer, hereditary, 12",
                "description": "Prostate cancer, hereditary, 12"
            },
            {
                "id": "MIM:611928",
                "resource": "MIM",
                "url": "https://www.omim.org/entry/611928",
                "name": "Prostate cancer, hereditary, 13",
                "description": "Prostate cancer, hereditary, 13"
            },
            {
                "id": "MIM:611955",
                "resource": "MIM",
                "url": "https://www.omim.org/entry/611955",
                "name": "Prostate cancer, hereditary, 11",
                "description": "Prostate cancer, hereditary, 11"
            },
            {
                "id": "MIM:176807",
                "resource": "MIM",
                "url": "https://www.omim.org/entry/176807",
                "name": "Prostate cancer",
                "description": "Prostate cancer"
            }
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                        }
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                }
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            "evidence_list": [
                {
                    "evidence": "TM256 and LAMTOR1 could be used to augment the sensitivity to 100%. Other prominent proteins were V-type proton ATPase 16 kDa proteolipid subunit (VATL), adipogenesis regulatory factor (ADIRF), and several Rab-class members and proteasomal proteins."
                }
            ]
        }
    ],
    "crossref": [
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            "id": "AN6585-1",
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            "url": "https://biomarkerkb.org/biomarker/AN6585-1",
            "categories": [
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        }
    ],
    "citation": [
        {
            "title": "Identification of prostate cancer biomarkers in urinary exosomes.",
            "journal": "Oncotarget",
            "authors": "Overbye A, Skotland T, Koehler CJ, Thiede B, Seierstad T, Berge V, Sandvig K, Llorente A",
            "date": "2015",
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                    "type": "PubMed",
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                }
            ],
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}