{
    "biomarker_id": "AN6580-1",
    "biomarker_canonical_id": "AN6580",
    "condition": {
        "recommended_name": {
            "id": "DOID:263",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:263",
            "name": "kidney cancer",
            "description": "A urinary system cancer that is located_in the kidney."
        },
        "synonyms": [
            {
                "id": "DOID:263",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:263",
                "name": "malignant neoplasm of kidney except pelvis",
                "description": ""
            },
            {
                "id": "DOID:263",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:263",
                "name": "malignant tumour of kidney",
                "description": ""
            },
            {
                "id": "DOID:263",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:263",
                "name": "renal cancer",
                "description": ""
            }
        ],
        "id": "DOID:263"
    },
    "biomarker_component": [
        {
            "biomarker": "increased ADFP level",
            "assessed_biomarker_entity_id": "Q99541-1",
            "assessed_entity_type": "protein",
            "assessed_biomarker_entity": {
                "recommended_name": "Perilipin-2",
                "synonyms": [
                    {
                        "synonym": "Adipose differentiation-related protein"
                    },
                    {
                        "synonym": "ADRP"
                    },
                    {
                        "synonym": "Adipophilin"
                    }
                ]
            },
            "specimen": [
                {
                    "name": "urine",
                    "namespace": "UBERON",
                    "id": "0001088",
                    "url": "http://purl.obolibrary.org/obo/UBERON_0001088",
                    "loinc_code": ""
                }
            ],
            "evidence_source": [
                {
                    "id": "AN6580-1",
                    "database": "BiomarkerKB",
                    "url": "https://biomarkerkb.org/biomarker/AN6580-1"
                },
                {
                    "id": "20375178",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/20375178",
                    "tags": [
                        "assessed_biomarker_entity",
                        " biomarker",
                        " specimen"
                    ],
                    "evidence_list": [
                        {
                            "evidence": "The ADFP concentrations in patients with either clear cell or papillary carcinoma were significantly greater and clearly separated from those in the nonnephrectomy surgical control patients and the healthy individuals. High ADFP concentration in the urine demonstrated 100% sensitivity and 100% specificity in detecting renal cancer."
                        }
                    ]
                }
            ]
        }
    ],
    "best_biomarker_role": [
        {
            "role": "diagnostic"
        }
    ],
    "evidence_source": [
        {
            "id": "AN6580-1",
            "database": "BiomarkerKB",
            "url": "https://biomarkerkb.org/biomarker/AN6580-1"
        },
        {
            "id": "20375178",
            "database": "PubMed",
            "url": "https://glygen.org/publication/PubMed/20375178",
            "tags": [
                "best_biomarker_role",
                " condition"
            ],
            "evidence_list": [
                {
                    "evidence": "The ADFP concentrations in patients with either clear cell or papillary carcinoma were significantly greater and clearly separated from those in the nonnephrectomy surgical control patients and the healthy individuals. High ADFP concentration in the urine demonstrated 100% sensitivity and 100% specificity in detecting renal cancer."
                }
            ]
        }
    ],
    "crossref": [
        {
            "id": "AN6580-1",
            "database": "BiomarkerKB",
            "url": "https://biomarkerkb.org/biomarker/AN6580-1",
            "categories": [
                "Biomarkers"
            ]
        }
    ],
    "citation": [
        {
            "title": "Urinary biomarkers for the early diagnosis of kidney cancer.",
            "journal": "Mayo Clinic proceedings",
            "authors": "Morrissey JJ, London AN, Luo J, Kharasch ED",
            "date": "2010",
            "reference": [
                {
                    "type": "PubMed",
                    "id": "20375178",
                    "url": "https://glygen.org/publication/PubMed/20375178"
                }
            ],
            "evidence": [
                {
                    "id": "AN6579-1",
                    "database": "BiomarkerKB",
                    "url": "https://biomarkerkb.org/biomarker/AN6580-1"
                }
            ]
        }
    ],
    "section_stats": [
        {
            "table_id": "biomarker_component",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                }
            ],
            "sort_fields": [
                "biomarker",
                "assessed_biomarker_entity_id",
                "assessed_entity_type",
                "assessed_biomarker_entity.recommended_name"
            ]
        },
        {
            "table_id": "citation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                }
            ],
            "sort_fields": [
                "title",
                "journal",
                "authors",
                "date"
            ]
        }
    ]
}