{
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    "biomarker_canonical_id": "AN6441",
    "condition": {
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            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0080600",
            "name": "COVID-19",
            "description": "A Coronavirus infectious disease that is characterized by fever, cough and shortness of breath and that has_material_basis_in Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a subtype of Betacoronavirus pandemicum."
        },
        "synonyms": [
            {
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                "resource": "Disease Ontology",
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                "description": ""
            },
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            },
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                "name": "SARS-CoV-2 infection",
                "description": ""
            },
            {
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                "name": "COVID-19",
                "description": "A disease caused by infection with severe acute respiratory syndrome coronavirus 2."
            },
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                "id": "MONDO:0100096",
                "resource": "MONDO",
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                "description": ""
            },
            {
                "id": "MONDO:0100096",
                "resource": "MONDO",
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                "name": "2019-nCoV infection",
                "description": ""
            },
            {
                "id": "MONDO:0100096",
                "resource": "MONDO",
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                "name": "coronavirus disease 2019",
                "description": ""
            },
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            },
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                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0100096",
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                "name": "SARS-coronavirus 2",
                "description": ""
            },
            {
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                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0100096",
                "name": "beta-CoV",
                "description": ""
            },
            {
                "id": "MONDO:0100096",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0100096",
                "name": "beta-CoVs",
                "description": ""
            },
            {
                "id": "MONDO:0100096",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0100096",
                "name": "betacoronavirus",
                "description": ""
            },
            {
                "id": "MONDO:0100096",
                "resource": "MONDO",
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                "name": "severe acute respiratory syndrome coronavirus 2",
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            },
            {
                "id": "MONDO:0100096",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0100096",
                "name": "-CoV",
                "description": ""
            },
            {
                "id": "MONDO:0100096",
                "resource": "MONDO",
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                "name": "-CoVs",
                "description": ""
            },
            {
                "id": "MONDO:0100096",
                "resource": "MONDO",
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                "name": "-coronavirus",
                "description": ""
            }
        ],
        "id": "DOID:0080600"
    },
    "biomarker_component": [
        {
            "biomarker": "increased TNNT2 level",
            "assessed_biomarker_entity_id": "P45379-1",
            "assessed_entity_type": "protein",
            "assessed_biomarker_entity": {
                "recommended_name": "Troponin T, cardiac muscle",
                "synonyms": [
                    {
                        "synonym": "Cardiac muscle troponin T"
                    },
                    {
                        "synonym": "cTnT"
                    }
                ]
            },
            "specimen": [
                {
                    "name": "blood",
                    "namespace": "UBERON",
                    "id": "0000178",
                    "url": "http://purl.obolibrary.org/obo/UBERON_0000178",
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                }
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                },
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                    "tags": [
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                        " biomarker",
                        " specimen"
                    ],
                    "evidence_list": [
                        {
                            "evidence": "In patients hospitalized with COVID-19, hs-TnT identifies patients at high risk for adverse in-hospital events, and trends of hs-TnT over time, particularly during the first day, provide additional prognostic information."
                        }
                    ]
                }
            ]
        }
    ],
    "best_biomarker_role": [
        {
            "role": "prognostic"
        }
    ],
    "evidence_source": [
        {
            "id": "AN6441-1",
            "database": "BiomarkerKB",
            "url": "https://biomarkerkb.org/biomarker/AN6441-1"
        },
        {
            "id": "33003961",
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            "url": "https://glygen.org/publication/PubMed/33003961",
            "tags": [
                "best_biomarker_role",
                " condition"
            ],
            "evidence_list": [
                {
                    "evidence": "In patients hospitalized with COVID-19, hs-TnT identifies patients at high risk for adverse in-hospital events, and trends of hs-TnT over time, particularly during the first day, provide additional prognostic information."
                }
            ]
        }
    ],
    "crossref": [
        {
            "id": "AN6441-1",
            "database": "BiomarkerKB",
            "url": "https://biomarkerkb.org/biomarker/AN6441-1",
            "categories": [
                "Biomarkers"
            ]
        }
    ],
    "citation": [
        {
            "title": "Association between cardiac troponin I and mortality in patients with COVID-19.",
            "journal": "Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals",
            "authors": "Salvatici M, Barbieri B, Cioffi SMG, Morenghi E, Leone FP, Maura F, Moriello G, Sandri MT",
            "date": "2020",
            "reference": [
                {
                    "type": "PubMed",
                    "id": "33003961",
                    "url": "https://glygen.org/publication/PubMed/33003961"
                }
            ],
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                {
                    "id": "AN6440-1",
                    "database": "BiomarkerKB",
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                }
            ]
        }
    ],
    "section_stats": [
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            ],
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                "assessed_biomarker_entity.recommended_name"
            ]
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}