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"id": "P0C1S8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P0C1S8" } ], "protein_name": "Wee1-like protein kinase 2", "gene_name": "WEE2", "tax_id": 9606, "tax_name": "Homo sapiens", "tax_common_name": "Human" }, { "uniprot_canonical_ac": "P0C221-1", "evidence": [ { "database": "PubMed", "id": "34019948", "url": "https://glygen.org/publication/PubMed/34019948" }, { "database": "O-GlcNAc Database", "id": "P0C221", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P0C221" } ], "protein_name": "Coiled-coil domain-containing protein 175", "gene_name": "CCDC175", "tax_id": 9606, "tax_name": "Homo sapiens", "tax_common_name": "Human" }, { "uniprot_canonical_ac": "P0C2L3-1", "evidence": [ { "database": "PubMed", "id": "39894887", "url": "https://glygen.org/publication/PubMed/39894887" }, { "database": "O-GlcNAc Database", "id": "P0C2L3", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P0C2L3" } ], "protein_name": "Protein FAM163B", "gene_name": "FAM163B", 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"27566657", "url": "https://glygen.org/publication/PubMed/27566657" }, { "database": "PubMed", "id": "23271734", "url": "https://glygen.org/publication/PubMed/23271734" }, { "database": "PubMed", "id": "15158436", "url": "https://glygen.org/publication/PubMed/15158436" }, { "database": "PubMed", "id": "35138101", "url": "https://glygen.org/publication/PubMed/35138101" }, { "database": "PubMed", "id": "34725712", "url": "https://glygen.org/publication/PubMed/34725712" } ], "protein_name": "Heat shock 70 kDa protein 1B", "gene_name": "HSPA1B", "tax_id": 9606, "tax_name": "Homo sapiens", "tax_common_name": "Human" }, { "uniprot_canonical_ac": "P0DN25-1", "start_pos": 5, "end_pos": 5, "residue": "Ser", "evidence": [ { "database": "PubMed", "id": "31492838", "url": "https://glygen.org/publication/PubMed/31492838" }, { "database": "O-GlcNAc Database", "id": "P0DN25", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P0DN25" }, { "database": "PubMed", "id": "37217939", "url": "https://glygen.org/publication/PubMed/37217939" }, { "database": "O-GlcNAc Atlas", "id": "P0DN25", "url": "https://oglcnac.org/atlas/detail/P0DN25" } ], "protein_name": "C1GALT1-specific chaperone 1-like protein", "gene_name": "C1GALT1C1L", "tax_id": 9606, "tax_name": "Homo sapiens", "tax_common_name": "Human" }, { "uniprot_canonical_ac": "P0DN25-1", "start_pos": 7, "end_pos": 7, "residue": "Thr", "evidence": [ { "database": "PubMed", "id": "31492838", "url": "https://glygen.org/publication/PubMed/31492838" }, { "database": "O-GlcNAc Database", "id": "P0DN25", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P0DN25" }, { "database": "PubMed", "id": "37217939", "url": "https://glygen.org/publication/PubMed/37217939" }, { "database": "O-GlcNAc Atlas", "id": "P0DN25", "url": "https://oglcnac.org/atlas/detail/P0DN25" } ], "protein_name": "C1GALT1-specific chaperone 1-like protein", "gene_name": "C1GALT1C1L", "tax_id": 9606, "tax_name": "Homo sapiens", "tax_common_name": "Human" }, { "uniprot_canonical_ac": "P0DN25-1", "start_pos": 8, "end_pos": 8, "residue": "Ser", "evidence": [ { "database": "PubMed", "id": "31492838", "url": "https://glygen.org/publication/PubMed/31492838" }, { "database": "O-GlcNAc Database", "id": "P0DN25", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P0DN25" }, { "database": "PubMed", "id": "37217939", "url": "https://glygen.org/publication/PubMed/37217939" }, { "database": "O-GlcNAc Atlas", "id": "P0DN25", "url": "https://oglcnac.org/atlas/detail/P0DN25" } ], "protein_name": "C1GALT1-specific chaperone 1-like protein", "gene_name": "C1GALT1C1L", "tax_id": 9606, "tax_name": "Homo sapiens", "tax_common_name": "Human" }, { "uniprot_canonical_ac": "P0DN37-1", "evidence": [ { "database": "PubMed", "id": "39894887", "url": "https://glygen.org/publication/PubMed/39894887" }, { "database": "O-GlcNAc Database", "id": "P0DN37", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P0DN37" } ], "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4G", "gene_name": "PPIAL4G", "tax_id": 9606, "tax_name": "Homo sapiens", "tax_common_name": "Human" }, { "uniprot_canonical_ac": "P0DN81-1", "start_pos": 155, "end_pos": 155, "residue": "Thr", "evidence": [ { "database": "PubMed", "id": "38253038", "url": "https://glygen.org/publication/PubMed/38253038" }, { "database": "O-GlcNAc Database", "id": "P0DN81", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P0DN81" } ], "protein_name": "Olfactory receptor 13C7", "gene_name": "OR13C7", "tax_id": 9606, "tax_name": "Homo sapiens", "tax_common_name": "Human" }, { "uniprot_canonical_ac": "P0DN86-1", "evidence": [ { "database": "PubMed", "id": "39894887", "url": "https://glygen.org/publication/PubMed/39894887" }, { "database": "O-GlcNAc Database", "id": "P0DN86", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P0DN86" } ], "protein_name": "Choriogonadotropin subunit beta 3", "gene_name": "CGB3", "tax_id": 9606, "tax_name": "Homo sapiens", "tax_common_name": "Human" }, { "uniprot_canonical_ac": "P0DO97-1", "start_pos": 25, "end_pos": 25, "residue": "Ser", "evidence": [ { "database": "PubMed", "id": "38253038", "url": "https://glygen.org/publication/PubMed/38253038" }, { "database": "O-GlcNAc Database", "id": "P0DO97", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P0DO97" } ], "protein_name": "Coiled-coil domain-containing protein 192", "gene_name": "CCDC192", "tax_id": 9606, "tax_name": "Homo sapiens", "tax_common_name": "Human" }, { "uniprot_canonical_ac": "P0DO97-1", "start_pos": 28, "end_pos": 28, "residue": "Ser", "evidence": [ { "database": "PubMed", "id": "38253038", "url": "https://glygen.org/publication/PubMed/38253038" }, { "database": "O-GlcNAc Database", "id": "P0DO97", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P0DO97" } ], "protein_name": "Coiled-coil domain-containing protein 192", "gene_name": "CCDC192", "tax_id": 9606, "tax_name": "Homo sapiens", "tax_common_name": "Human" }, { "uniprot_canonical_ac": "P0DP23-1", "evidence": [ { "database": "PubMed", "id": "30444036", "url": "https://glygen.org/publication/PubMed/30444036" }, { "database": "O-GlcNAc Database", "id": "P0DP23", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P0DP23" }, { "database": "PubMed", "id": "28657654", "url": "https://glygen.org/publication/PubMed/28657654" } ], "protein_name": "Calmodulin-1", "gene_name": "CALM1", "tax_id": 9606, "tax_name": "Homo sapiens", "tax_common_name": "Human" }, { "uniprot_canonical_ac": "P0DP24-1", "evidence": [ { "database": "PubMed", "id": "30444036", "url": "https://glygen.org/publication/PubMed/30444036" }, { "database": "O-GlcNAc Database", "id": "P0DP24", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P0DP24" }, { "database": "PubMed", "id": "28657654", "url": "https://glygen.org/publication/PubMed/28657654" } ], "protein_name": "Calmodulin-2", "gene_name": "CALM2", "tax_id": 9606, "tax_name": "Homo sapiens", "tax_common_name": "Human" }, { "uniprot_canonical_ac": "P0DP25-1", "evidence": [ { "database": "PubMed", "id": "30444036", "url": "https://glygen.org/publication/PubMed/30444036" }, { "database": "O-GlcNAc Database", "id": "P0DP25", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P0DP25" }, { "database": "PubMed", "id": "33214551", "url": "https://glygen.org/publication/PubMed/33214551" }, { "database": "PubMed", "id": "28657654", "url": "https://glygen.org/publication/PubMed/28657654" }, { "database": "PubMed", "id": "34019948", "url": "https://glygen.org/publication/PubMed/34019948" } ], "protein_name": "Calmodulin-3", "gene_name": "CALM3", "tax_id": 9606, "tax_name": "Homo sapiens", "tax_common_name": "Human" }, { "uniprot_canonical_ac": "P0DP73-1", "evidence": [ { "database": "PubMed", "id": "37217939", "url": "https://glygen.org/publication/PubMed/37217939" }, { "database": "O-GlcNAc Database", "id": "P0DP73", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P0DP73" } ], "protein_name": "Beta-defensin 130B", "gene_name": "DEFB130B", "tax_id": 9606, "tax_name": "Homo sapiens", "tax_common_name": "Human" }, { "uniprot_canonical_ac": "P0DP75-1", "evidence": [ { "database": "PubMed", "id": "37217939", "url": "https://glygen.org/publication/PubMed/37217939" }, { "database": "O-GlcNAc Database", "id": "P0DP75", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P0DP75" } ], "protein_name": "Putative uncharacterized protein MED14OS", "gene_name": "MED14OS", "tax_id": 9606, "tax_name": "Homo sapiens", "tax_common_name": "Human" }, { "uniprot_canonical_ac": "P0DPA2-1", "evidence": [ { "database": "PubMed", "id": "39894887", "url": "https://glygen.org/publication/PubMed/39894887" }, { "database": "O-GlcNAc Database", "id": "P0DPA2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P0DPA2" } ], "protein_name": "V-set and immunoglobulin domain-containing protein 8", "gene_name": "VSIG8", "tax_id": 9606, "tax_name": "Homo sapiens", "tax_common_name": "Human" }, { "uniprot_canonical_ac": "P0DPB6-1", "evidence": [ { "database": "PubMed", "id": "28510447", "url": "https://glygen.org/publication/PubMed/28510447" }, { "database": "O-GlcNAc Database", "id": "P0DPB6", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P0DPB6" } ], "protein_name": "DNA-directed RNA polymerases I and III subunit RPAC2", "gene_name": "POLR1D", "tax_id": 9606, "tax_name": "Homo sapiens", "tax_common_name": "Human" }, { "uniprot_canonical_ac": "P0DPD6-4", "evidence": [ { "database": "PubMed", "id": "28510447", "url": "https://glygen.org/publication/PubMed/28510447" }, { "database": "O-GlcNAc Database", "id": "P0DPD6", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P0DPD6" } ], "protein_name": "Endothelin-converting enzyme 2", "gene_name": "ECE2", "tax_id": 9606, "tax_name": "Homo sapiens", "tax_common_name": "Human" }, { "uniprot_canonical_ac": "P0DPD7-4", "evidence": [ { "database": "PubMed", "id": "28510447", "url": "https://glygen.org/publication/PubMed/28510447" }, { "database": "O-GlcNAc Database", "id": "P0DPD7", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P0DPD7" } ], "protein_name": "EEF1A lysine methyltransferase 4", "gene_name": "EEF1AKMT4", "tax_id": 9606, "tax_name": "Homo sapiens", "tax_common_name": "Human" }, { "uniprot_canonical_ac": "P0DPD8-1", "start_pos": 573, "end_pos": 573, "residue": "Ser", "evidence": [ { "database": "PubMed", "id": "28510447", "url": "https://glygen.org/publication/PubMed/28510447" }, { "database": "O-GlcNAc Database", "id": "P0DPD8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P0DPD8" }, { "database": "PubMed", "id": "38253038", "url": "https://glygen.org/publication/PubMed/38253038" } ], "protein_name": "EEF1AKMT4-ECE2 readthrough transcript protein", "gene_name": "EEF1AKMT4-ECE2", "tax_id": 9606, "tax_name": "Homo sapiens", "tax_common_name": "Human" }, { "uniprot_canonical_ac": "P0DPH7-1", "evidence": [ { "database": "PubMed", "id": "30397120", "url": "https://glygen.org/publication/PubMed/30397120" }, { "database": "O-GlcNAc Database", "id": "P0DPH7", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P0DPH7" }, { "database": "PubMed", "id": "30796923", "url": "https://glygen.org/publication/PubMed/30796923" } ], "protein_name": "Tubulin alpha-3C chain", "gene_name": "TUBA3C", "tax_id": 9606, "tax_name": "Homo sapiens", "tax_common_name": "Human" }, { "uniprot_canonical_ac": "P0DPH8-1", "evidence": [ { "database": "PubMed", "id": "30397120", "url": "https://glygen.org/publication/PubMed/30397120" }, { "database": "O-GlcNAc Database", "id": "P0DPH8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P0DPH8" }, { "database": "PubMed", "id": "37217939", "url": "https://glygen.org/publication/PubMed/37217939" }, { "database": "PubMed", "id": "30796923", "url": "https://glygen.org/publication/PubMed/30796923" } ], "protein_name": "Tubulin alpha-3D chain", "gene_name": "TUBA3D", "tax_id": 9606, 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"type": "PubMed", "id": "27713473", "url": "https://glygen.org/publication/PubMed/27713473" } ] }, { "title": "A peptide panel investigation reveals the acceptor specificity of O-GlcNAc transferase.", "journal": "FASEB journal : official publication of the Federation of American Societies for Experimental Biology", "date": "2014", "authors": "Liu X, Li L, Wang Y, Yan H, Ma X, Wang PG, Zhang L", "evidence": [ { "database": "O-GlcNAc Database", "id": "O15294", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O15294" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "24760753", "url": "https://glygen.org/publication/PubMed/24760753" } ] }, { "title": "O-GlcNAcylation of Thr(12)/Ser(56) in short-form O-GlcNAc transferase (sOGT) regulates its substrate selectivity.", "journal": "The Journal of biological chemistry", "date": "2019", "authors": "Liu L, Li L, Ma C, Shi Y, Liu C, Xiao 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"authors": "Shin H, Cha HJ, Na K, Lee MJ, Cho JY, Kim CY, Kim EK, Kang CM, Kim H, Paik YK", "evidence": [ { "database": "O-GlcNAc Database", "id": "O43524", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O43524" }, { "database": "O-GlcNAc Atlas", "id": "O43524", "url": "https://oglcnac.org/atlas/detail/O43524" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "29301793", "url": "https://glygen.org/publication/PubMed/29301793" } ] }, { "title": "O-GlcNAc transferase enables AgRP neurons to suppress browning of white fat.", "journal": "Cell", "date": "2014", "authors": "Ruan HB, Dietrich MO, Liu ZW, Zimmer MR, Li MD, Singh JP, Zhang K, Yin R, Wu J, Horvath TL, Yang X", "evidence": [ { "database": "O-GlcNAc Database", "id": "O43525", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O43525" }, { "database": "GlyTouCan", "id": "G49108TO", "url": 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of hepatocellular carcinoma.", "journal": "Aging", "date": "2020", "authors": "Wang J, Wang Z, Yuan J, Wang J, Shen X", "evidence": [ { "database": "O-GlcNAc Database", "id": "O60488", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O60488" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "32357142", "url": "https://glygen.org/publication/PubMed/32357142" } ] }, { "title": "Recombinant O-GlcNAc transferase isoforms: identification of O-GlcNAcase, yes tyrosine kinase, and tau as isoform-specific substrates.", "journal": "Glycobiology", "date": "2006", "authors": "Lazarus BD, Love DC, Hanover JA", "evidence": [ { "database": "O-GlcNAc Database", "id": "O60502", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O60502" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": 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"date": "2011", "authors": "Skorobogatko YV, Deuso J, Adolf-Bryfogle J, Nowak MG, Gong Y, Lippa CF, Vosseller K", "evidence": [ { "database": "O-GlcNAc Database", "id": "O94811", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O94811" }, { "database": "O-GlcNAc Database", "id": "P36507", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P36507" }, { "database": "O-GlcNAc Database", "id": "Q16186", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q16186" }, { "database": "O-GlcNAc Database", "id": "Q9UPA5", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9UPA5" }, { "database": "O-GlcNAc Database", "id": "Q9Y6V0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9Y6V0" }, { "database": "O-GlcNAc Atlas", "id": "P36507", "url": "https://oglcnac.org/atlas/detail/P36507" }, { "database": "O-GlcNAc Atlas", "id": "Q9UPA5", "url": "https://oglcnac.org/atlas/detail/Q9UPA5" }, { "database": "O-GlcNAc Atlas", "id": "Q9Y6V0", "url": 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"database": "O-GlcNAc Atlas", "id": "O94979", "url": "https://oglcnac.org/atlas/detail/O94979" }, { "database": "O-GlcNAc Atlas", "id": "P53992", "url": "https://oglcnac.org/atlas/detail/P53992" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "34142147", "url": "https://glygen.org/publication/PubMed/34142147" } ] }, { "title": "O-GlcNAcylation regulates endoplasmic reticulum exit sites through Sec31A modification in conventional secretory pathway.", "journal": "FASEB journal : official publication of the Federation of American Societies for Experimental Biology", "date": "2018", "authors": "Cho HJ, Mook-Jung I", "evidence": [ { "database": "O-GlcNAc Database", "id": "O94979", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O94979" }, { "database": "O-GlcNAc Atlas", "id": "O94979", "url": "https://oglcnac.org/atlas/detail/O94979" }, { "database": "GlyTouCan", "id": 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"https://glygen.org/publication/PubMed/22664592" } ] }, { "title": "O-GlcNAc Modification Alters the Chaperone Activity of HSP27 Charcot-Marie-Tooth Type 2 (CMT2) Variants in a Mutation-Selective Fashion.", "journal": "ACS chemical biology", "date": "2023-08-18", "authors": "Moon Stuart P, Wang Binyou, Ahn Benjamin S, Ryu Andrew H, Hard Eldon R, Javed Afraah, Pratt Matthew R", "evidence": [ { "database": "O-GlcNAc Database", "id": "P04792", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P04792" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "37540114", "url": "https://glygen.org/publication/PubMed/37540114" } ] }, { "title": "Thymidylate synthase O-GlcNAcylation: a molecular mechanism of 5-FU sensitization in colorectal cancer.", "journal": "Oncogene", "date": "2022", "authors": "Very N, Hardiville S, Decourcelle A, Thevenet J, Djouina M, Page A, Vergoten G, Schulz C, Kerr-Conte J, Lefebvre T, Dehennaut V, El Yazidi-Belkoura I", "evidence": [ { "database": "O-GlcNAc Database", "id": "P04818", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P04818" }, { "database": "O-GlcNAc Atlas", "id": "P04818", "url": "https://oglcnac.org/atlas/detail/P04818" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "34845374", "url": "https://glygen.org/publication/PubMed/34845374" } ] }, { "title": "Beta-N-acetylglucosamine (O-GlcNAc) is part of the histone code.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2010", "authors": "Sakabe K, Wang Z, Hart GW", "evidence": [ { "database": "O-GlcNAc Database", "id": "P04908", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P04908" }, { "database": "O-GlcNAc Database", "id": "P62805", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P62805" 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"database": "O-GlcNAc Database", "id": "P16104", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P16104" }, { "database": "O-GlcNAc Database", "id": "P68431", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P68431" }, { "database": "O-GlcNAc Database", "id": "P84243", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P84243" }, { "database": "O-GlcNAc Database", "id": "Q16695", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q16695" }, { "database": "O-GlcNAc Database", "id": "Q16777", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q16777" }, { "database": "O-GlcNAc Database", "id": "Q5QNW6", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q5QNW6" }, { "database": "O-GlcNAc Database", "id": "Q71UI9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q71UI9" }, { "database": "O-GlcNAc Database", "id": "Q7L7L0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7L7L0" }, { "database": "O-GlcNAc Database", "id": "Q8IUE6", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8IUE6" }, { "database": "O-GlcNAc Database", "id": "Q96A08", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q96A08" }, { "database": "O-GlcNAc Database", "id": "Q99880", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q99880" }, { "database": "O-GlcNAc Atlas", "id": "P68431", "url": "https://oglcnac.org/atlas/detail/P68431" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" }, { "database": "GlyConnect", "id": "2886", "url": "https://glyconnect.expasy.org/browser/proteins/2886" } ], "reference": [ { "type": "PubMed", "id": "21896475", "url": "https://glygen.org/publication/PubMed/21896475" } ] }, { "title": "H2A O-GlcNAcylation at serine 40 functions genomic protection in association with acetylated H2AZ or gammaH2AX.", "journal": "Epigenetics & chromatin", "date": "2017", "authors": "Hayakawa K, Hirosawa M, Tani R, Yoneda C, Tanaka S, Shiota 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"journal": "Biochimica et biophysica acta", "date": "2015", "authors": "Jang I, Kim HB, Seo H, Kim JY, Choi H, Yoo JS, Kim JW, Cho JW", "evidence": [ { "database": "O-GlcNAc Database", "id": "P05198", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P05198" }, { "database": "O-GlcNAc Atlas", "id": "P05198", "url": "https://oglcnac.org/atlas/detail/P05198" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "25937070", "url": "https://glygen.org/publication/PubMed/25937070" } ] }, { "title": "Time-resolved multiomics profiling reveals chromatin O-GlcNAc modification promotes senescence-associated transcriptional program.", "journal": "Nature communications", "date": "2026-01-08", "authors": "Zhang Nana, Zhao Ran, Zhong Xiaomin, Dong Qian, Liu Yajie, Yu Kairan, Han Lirui, Meng Fanxu, Wu Jiaxuan, Chen Qiushi, Li Xuechen, Chen Qingbin, Zhang Keren, Huang Huang, Zhang Jianing, Wu Sijin, Ren Yan, Wang Wei, Liu Yubo", "evidence": [ { "database": "O-GlcNAc Database", "id": "P05412", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P05412" }, { "database": "O-GlcNAc Database", "id": "P85037", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P85037" }, { "database": "O-GlcNAc Database", "id": "Q68CP9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q68CP9" }, { "database": "O-GlcNAc Database", "id": "Q86YP4", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q86YP4" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "41507163", "url": "https://glygen.org/publication/PubMed/41507163" } ] }, { "title": "O-GlcNAcylated c-Jun antagonizes ferroptosis via inhibiting GSH synthesis in liver cancer.", "journal": "Cellular signalling", "date": "2019", "authors": "Chen Y, Zhu G, Liu Y, Wu Q, Zhang X, Bian Z, Zhang Y, Pan Q, Sun F", "evidence": [ { "database": "O-GlcNAc Database", "id": "P05412", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P05412" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "31394193", "url": "https://glygen.org/publication/PubMed/31394193" } ] }, { "title": "Target protein deglycosylation in living cells by a nanobody-fused split O-GlcNAcase.", "journal": "Nature chemical biology", "date": "2021", "authors": "Ge Y, Ramirez DH, Yang B, D'Souza AK, Aonbangkhen C, Wong S, Woo CM", "evidence": [ { "database": "O-GlcNAc Database", "id": "P05412", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P05412" }, { "database": "O-GlcNAc Database", "id": "P08047", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08047" }, { "database": "O-GlcNAc Database", "id": "P17275", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P17275" }, { "database": "O-GlcNAc 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the level of O-linked N-acetylglucosamine and accumulation of incompletely processed N-glycans on proteins from HT29 cells.", "journal": "The Journal of biological chemistry", "date": "1997", "authors": "Haltiwanger RS, Philipsberg GA", "evidence": [ { "database": "O-GlcNAc Database", "id": "P05783", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P05783" }, { "database": "O-GlcNAc Database", "id": "P08047", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08047" }, { "database": "O-GlcNAc Database", "id": "P37198", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P37198" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "9079710", "url": "https://glygen.org/publication/PubMed/9079710" } ] }, { "title": "O-GlcNAcylation determines the solubility, filament organization, and stability of keratins 8 and 18.", "journal": "The Journal of biological chemistry", "date": "2010", "authors": "Srikanth B, Vaidya MM, Kalraiya RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "P05783", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P05783" }, { "database": "O-GlcNAc Database", "id": "P05787", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P05787" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "20729549", "url": "https://glygen.org/publication/PubMed/20729549" } ] }, { "title": "Functional Implications of O-GlcNAcylation-dependent Phosphorylation at a Proximal Site on Keratin 18.", "journal": "The Journal of biological chemistry", "date": "2016", "authors": "Kakade PS, Budnar S, Kalraiya RD, Vaidya MM", "evidence": [ { "database": "O-GlcNAc Database", "id": "P05783", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P05783" }, { "database": "GlyTouCan", "id": "G49108TO", "url": 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"authors": "Ku NO, Omary MB", "evidence": [ { "database": "O-GlcNAc Database", "id": "P05783", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P05783" }, { "database": "O-GlcNAc Atlas", "id": "P05783", "url": "https://oglcnac.org/atlas/detail/P05783" }, { "database": "UniCarbKB", "id": "GLY_000040", "url": "http://data.glygen.org/GLY_000040" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" }, { "database": "GlyConnect", "id": "312", "url": "https://glyconnect.expasy.org/browser/proteins/312" } ], "reference": [ { "type": "PubMed", "id": "7538124", "url": "https://glygen.org/publication/PubMed/7538124" } ] }, { "title": "Development of in vitro model of insulin receptor cleavage induced by high glucose in HepG2 cells.", "journal": "Biochemical and biophysical research communications", "date": "2014", "authors": "Yuasa T, Amo K, Ishikura S, Nagaya H, Uchiyama K, Hashida S, Ebina Y", "evidence": [ { "database": "O-GlcNAc 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"2019", "authors": "Cao B, Duan M, Xing Y, Liu C, Yang F, Li Y, Yang T, Wei Y, Gao Q, Jiang J", "evidence": [ { "database": "O-GlcNAc Database", "id": "P06730", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P06730" }, { "database": "O-GlcNAc Atlas", "id": "P06730", "url": "https://oglcnac.org/atlas/detail/P06730" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "30677218", "url": "https://glygen.org/publication/PubMed/30677218" } ] }, { "title": "O-GlcNAcylation increases PYGL activity by promoting phosphorylation.", "journal": "Glycobiology", "date": "2022", "authors": "Chen YF, Zhu JJ, Li J, Ye XS", "evidence": [ { "database": "O-GlcNAc Database", "id": "P06737", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P06737" }, { "database": "O-GlcNAc Atlas", "id": "P06737", "url": "https://oglcnac.org/atlas/detail/P06737" }, { "database": "GlyTouCan", "id": 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Endocrinology and metabolism", "date": "2008", "authors": "Soesanto YA, Luo B, Jones D, Taylor R, Gabrielsen JS, Parker G, McClain DA", "evidence": [ { "database": "O-GlcNAc Database", "id": "P31749", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P31749" }, { "database": "O-GlcNAc Database", "id": "P31751", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P31751" }, { "database": "O-GlcNAc Database", "id": "Q9Y243", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9Y243" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "18728220", "url": "https://glygen.org/publication/PubMed/18728220" } ] }, { "title": "Extensive crosstalk between O-GlcNAcylation and phosphorylation regulates Akt signaling.", "journal": "PloS one", "date": "2012", "authors": "Wang S, Huang X, Sun D, Xin X, Pan Q, Peng S, Liang Z, Luo C, Yang Y, Jiang H, Huang M, Chai W, Ding J, Geng 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{ "title": "Quantitative chemoproteomics reveals O-GlcNAcylation of cystathionine gamma-lyase (CSE) represses trophoblast syncytialization.", "journal": "Cell chemical biology", "date": "2021", "authors": "Liu J, Shao X, Qin W, Zhang Y, Dang F, Yang Q, Yu X, Li YX, Chen X, Wang C, Wang YL", "evidence": [ { "database": "O-GlcNAc Database", "id": "P32929", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P32929" }, { "database": "O-GlcNAc Atlas", "id": "P32929", "url": "https://oglcnac.org/atlas/detail/P32929" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "33626323", "url": "https://glygen.org/publication/PubMed/33626323" } ] }, { "title": "O-GlcNAc-glycosylation of beta-catenin regulates its nuclear localization and transcriptional activity.", "journal": "Experimental cell research", "date": "2008", "authors": "Sayat R, Leber B, Grubac V, Wiltshire L, Persad S", 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Timothy J, Wang Ting, Hu Junhao, Xu Heping, Chen Mei, Yan Hua, Wang Xiaohong", "evidence": [ { "database": "O-GlcNAc Database", "id": "P46937", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P46937" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "39472558", "url": "https://glygen.org/publication/PubMed/39472558" } ] }, { "title": "The essential role of YAP O-GlcNAcylation in high-glucose-stimulated liver tumorigenesis.", "journal": "Nature communications", "date": "2017", "authors": "Zhang X, Qiao Y, Wu Q, Chen Y, Zou S, Liu X, Zhu G, Zhao Y, Chen Y, Yu Y, Pan Q, Wang J, Sun F", "evidence": [ { "database": "O-GlcNAc Database", "id": "P46937", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P46937" }, { "database": "O-GlcNAc Atlas", "id": "P46937", "url": "https://oglcnac.org/atlas/detail/P46937" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "28474680", "url": "https://glygen.org/publication/PubMed/28474680" } ] }, { "title": "Regulation of the Hippo-YAP Pathway by Glucose Sensor O-GlcNAcylation.", "journal": "Molecular cell", "date": "2017", "authors": "Peng C, Zhu Y, Zhang W, Liao Q, Chen Y, Zhao X, Guo Q, Shen P, Zhen B, Qian X, Yang D, Zhang JS, Xiao D, Qin W, Pei H", "evidence": [ { "database": "O-GlcNAc Database", "id": "P46937", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P46937" }, { "database": "O-GlcNAc Atlas", "id": "P46937", "url": "https://oglcnac.org/atlas/detail/P46937" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "29100056", "url": "https://glygen.org/publication/PubMed/29100056" } ] }, { "title": "O-GlcNAcylation of Sox2 at threonine 258 regulates the self-renewal and early cell fate of embryonic stem cells.", "journal": "Experimental & molecular medicine", "date": "2021", "authors": "Kim DK, Lee JS, Lee EY, Jang H, Han S, Kim HY, Hwang IY, Choi JW, Shin HM, You HJ, Youn HD, Jang H", "evidence": [ { "database": "O-GlcNAc Database", "id": "P48431", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P48431" }, { "database": "O-GlcNAc Atlas", "id": "P48432", "url": "https://oglcnac.org/atlas/detail/P48432" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "34819616", "url": "https://glygen.org/publication/PubMed/34819616" } ] }, { "title": "O-GlcNAc modification of Sox2 regulates self-renewal in pancreatic cancer by promoting its stability.", "journal": "Theranostics", "date": "2019", "authors": "Sharma NS, Gupta VK, Dauer P, Kesh K, Hadad R, Giri B, Chandra A, Dudeja V, Slawson C, Banerjee S, Vickers SM, Saluja A, Banerjee S", "evidence": [ { "database": 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preferentially interact via their respective N-terminal regions.", "journal": "Biochemistry and biophysics reports", "date": "2026-03", "authors": "Vanauberg Dimitri, Schulz C\u00e9line, Brysbaert Guillaume, Raouraoua Nessim, Mistarz-Gruau Peggy, Lensink Marc F, Vercoutter-Edouart Anne-Sophie, Lefebvre Tony", "evidence": [ { "database": "O-GlcNAc Database", "id": "P49327", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P49327" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "41550490", "url": "https://glygen.org/publication/PubMed/41550490" } ] }, { "title": "O-GlcNAcylation of Fatty Acid Synthase is required for its proper subcellular localization, expression level and activity.", "journal": "The Journal of biological chemistry", "date": "2025-07-18", "authors": "Vanauberg Dimitri, Schulz C\u00e9line, Raab Sadia, Fuentes-Garcia Gabriela, Cadart Emilie, Lemaire Quentin, Olivier-Van Stichelen St\u00e9phanie, Bray Fabrice, Brysbaert Guillaume, Rossez Yannick, Hardivill\u00e9 St\u00e9phan, Lefebvre Tony", "evidence": [ { "database": "O-GlcNAc Database", "id": "P49327", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P49327" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "40684943", "url": "https://glygen.org/publication/PubMed/40684943" } ] }, { "title": "The Nutrient-Dependent O-GlcNAc Modification Controls the Expression of Liver Fatty Acid Synthase.", "journal": "Journal of molecular biology", "date": "2016", "authors": "Baldini SF, Wavelet C, Hainault I, Guinez C, Lefebvre T", "evidence": [ { "database": "O-GlcNAc Database", "id": "P49327", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P49327" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { 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Landrieu Isabelle, Smet-Nocca Caroline", "evidence": [ { "database": "O-GlcNAc Database", "id": "P49841", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P49841" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "38788673", "url": "https://glygen.org/publication/PubMed/38788673" } ] }, { "title": "Elevated O-GlcNAcylation stabilizes FOXM1 by its reduced degradation through GSK-3beta inactivation in a human gastric carcinoma cell line, MKN45 cells.", "journal": "Biochemical and biophysical research communications", "date": "2018", "authors": "Inoue Y, Moriwaki K, Ueda Y, Takeuchi T, Higuchi K, Asahi M", "evidence": [ { "database": "O-GlcNAc Database", "id": "P49841", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P49841" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "29196265", "url": "https://glygen.org/publication/PubMed/29196265" } ] }, { "title": "Multiple reaction monitoring mass spectrometry for the discovery and quantification of O-GlcNAc-modified proteins.", "journal": "Analytical chemistry", "date": "2014", "authors": "Maury JJ, Ng D, Bi X, Bardor M, Choo AB", "evidence": [ { "database": "O-GlcNAc Database", "id": "P49841", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P49841" }, { "database": "O-GlcNAc Atlas", "id": "P49841", "url": "https://oglcnac.org/atlas/detail/P49841" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "24144119", "url": "https://glygen.org/publication/PubMed/24144119" } ] }, { "title": "O-GlcNAc transferase couples MRE11 to transcriptionally active chromatin to suppress DNA damage.", "journal": "Journal of biomedical science", "date": "2022", "authors": "Gondane A, Girmay S, Heleva A, Pallasaho S, Loda M, Itkonen HM", "evidence": [ { "database": "O-GlcNAc Database", "id": "P49959", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P49959" }, { "database": "O-GlcNAc Database", "id": "P50750", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P50750" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "35164752", "url": "https://glygen.org/publication/PubMed/35164752" } ] }, { "title": "O-Linked beta-N-acetylglucosamine (O-GlcNAc) regulates emerin binding to barrier to autointegration factor (BAF) in a chromatin- and lamin B-enriched `niche`.", "journal": "The Journal of biological chemistry", "date": "2013", "authors": "Berk JM, Maitra S, Dawdy AW, Shabanowitz J, Hunt DF, Wilson KL", "evidence": [ { "database": "O-GlcNAc Database", "id": "P50402", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P50402" }, { "database": "O-GlcNAc Atlas", "id": "P50402", 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"https://glygen.org/publication/PubMed/40959291" } ] }, { "title": "Loss of O-GlcNAcylation on MeCP2 at Threonine 203 Leads to Neurodevelopmental Disorders.", "journal": "Neuroscience bulletin", "date": "2022", "authors": "Cheng J, Zhao Z, Chen L, Li Y, Du R, Wu Y, Zhu Q, Fan M, Duan X, Wu H", "evidence": [ { "database": "O-GlcNAc Database", "id": "P51608", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P51608" }, { "database": "O-GlcNAc Database", "id": "Q9Z2D6", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9Z2D6" }, { "database": "O-GlcNAc Database", "id": "Q00566", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q00566" }, { "database": "O-GlcNAc Atlas", "id": "P51608", "url": "https://oglcnac.org/atlas/detail/P51608" }, { "database": "O-GlcNAc Atlas", "id": "Q9Z2D6", "url": "https://oglcnac.org/atlas/detail/Q9Z2D6" }, { "database": "O-GlcNAc Atlas", "id": "Q00566", "url": "https://oglcnac.org/atlas/detail/Q00566" }, { "database": "GlyTouCan", 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"P53350", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P53350" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "39614052", "url": "https://glygen.org/publication/PubMed/39614052" } ] }, { "title": "PI3K\u03b2 functions as a protein kinase to promote cellular protein O-GlcNAcylation and acetyl-CoA production for tumor growth.", "journal": "Molecular cell", "date": "2025-04-03", "authors": "He Xuxiao, Chen Deyu, Liu Guijun, Wu Qingang, Zhao Hong, Guo Dong, Jiang Xiaoming, Li Min, Meng Ying, Yin Yucheng, Ye Xianglai, Luo Shudi, Xia Yan, Hunter Tony, Lu Zhimin", "evidence": [ { "database": "O-GlcNAc Database", "id": "P53396", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P53396" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "40132583", "url": 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"https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "32863962", "url": "https://glygen.org/publication/PubMed/32863962" } ] }, { "title": "Reciprocal regulation of TWIST1 and OGT determines the decitabine efficacy in MDS/AML.", "journal": "Cell communication and signaling : CCS", "date": "2023-09-22", "authors": "Li Hongjiao, Wang Yi, Feng Shuang, Chang Kaijing, Yu Xinwen, Yang Fenfang, Huang Haozhe, Wang Yuanbo, Li Xiang, Guan Feng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q15672", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q15672" }, { "database": "O-GlcNAc Atlas", "id": "Q15672", "url": "https://oglcnac.org/atlas/detail/Q15672" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "37736724", "url": "https://glygen.org/publication/PubMed/37736724" } ] }, { "title": "O-GlcNAc transferase invokes nucleotide 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"journal": "PloS one", "date": "2015", "authors": "Ding X, Jiang W, Zhou P, Liu L, Wan X, Yuan X, Wang X, Chen M, Chen J, Yang J, Kong C, Li B, Peng C, Wong CC, Hou F, Zhang Y", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8IZD2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8IZD2" }, { "database": "O-GlcNAc Atlas", "id": "Q8IZD2", "url": "https://oglcnac.org/atlas/detail/Q8IZD2" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "26678539", "url": "https://glygen.org/publication/PubMed/26678539" } ] }, { "title": "O-GlcNAcylation of MLL5beta is essential for MLL5beta-AP-1 transcription complex assembly at the HPV16/18-long control region.", "journal": "Journal of molecular cell biology", "date": "2015", "authors": "Nin DS, Huang W, Ali M, Yew CW, Kutateladze TG, Deng LW", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8IZD2", "url": 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O-GlcNAcylation of MAGI1 exacerbates high glucose-triggered inflammation and dedifferentiation of vascular smooth muscle cells by activating the PI3K/AKT pathway.", "journal": "Hereditas", "date": "2026-01-16", "authors": "Wen Li, Dai Ruijiang, Yu Shuang, Yu Houzhi", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q96QZ7", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q96QZ7" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "41546072", "url": "https://glygen.org/publication/PubMed/41546072" } ] }, { "title": "Erbin destabilization by O-GlcNAcylation promotes 5-FU resistance via homologous recombination activation in colorectal cancer.", "journal": "Biochemical pharmacology", "date": "2026-01", "authors": "Zhang Jianqing, Liu Chen, Tang Yujie, Gao Kangqi, Xu Weile, Zhang Jianfeng, Zhao Lianmei, Wang Guiying", "evidence": [ { "database": "O-GlcNAc Database", "id": 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Epithelial Phenotype in Conjunctival Epithelial Cells.", "journal": "Biochemical genetics", "date": "2024-04-16", "authors": "Xiong Wei-Wei, Ouyang Zi-Jing, Tan Yi, Xu Li-Wen, Peng Xiao-Wei", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q99102", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q99102" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "38627316", "url": "https://glygen.org/publication/PubMed/38627316" } ] }, { "title": "O-GlcNAcylation of DJ-1 suppresses ferroptosis in renal cell carcinoma by affecting the transsulfuration pathway.", "journal": "International immunopharmacology", "date": "2025-01-21", "authors": "Yan Zhiwei, Li Yanze, Wang Minghui, Xu Kai, Liu Yunxun, Wang Lei, Luo Hongbo, Chen Zhiyuan, Liu Xiuheng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q99497", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q99497" }, 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m6A reader YTHDF1 and colorectal cancer tumorigenesis.", "journal": "The Journal of biological chemistry", "date": "2023-04-20", "authors": "Li Jie, Ahmad Muhammad, Sang Lei, Zhan Yahui, Wang Yibo, Yan Yonghong, Liu Yue, Mi Weixiao, Lu Mei, Dai Yu, Zhang Rou, Dong Meng-Qiu, Yang Yun-Gui, Wang Xiaohui, Sun Jianwei, Li Jing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9BYJ9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9BYJ9" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "37086786", "url": "https://glygen.org/publication/PubMed/37086786" } ] }, { "title": "SETD5 regulates the OGT-catalyzed O-GlcNAcylation of RNA polymerase II, which is involved in the stemness of colorectal cancer cells.", "journal": "Scientific reports", "date": "2023-11-14", "authors": "Cho Hye In, Jo Sora, Kim Min Seong, Kim Han Byeol, Liu Xingzhe, Xuan Yanhua, Cho Jin Won, Jang Yeun 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O-GlcNAcylation promotes chromatin association of the ATAC complex and lung cancer tumorigenesis.", "journal": "The Journal of biological chemistry", "date": "2025-06-18", "authors": "Zhao Jianxin, Zhao Zheng, Zhou Wen, Zhang Jianzhi, Chen Jinfeng, Sun Jianwei, Li Jing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9ULM3", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9ULM3" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "40541806", "url": "https://glygen.org/publication/PubMed/40541806" } ] }, { "title": "O-GlcNAcylation Antagonizes Phosphorylation of CDH1 (CDC20 Homologue 1).", "journal": "The Journal of biological chemistry", "date": "2016", "authors": "Tian J, Geng Q, Ding Y, Liao J, Dong MQ, Xu X, Li J", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9UM11", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9UM11" }, { "database": 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regulates mitochondrial motility via Milton modification by O-GlcNAc transferase.", "journal": "Cell", "date": "2014", "authors": "Pekkurnaz G, Trinidad JC, Wang X, Kong D, Schwarz TL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9UPV9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9UPV9" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "24995978", "url": "https://glygen.org/publication/PubMed/24995978" } ] }, { "title": "Roles of the tetratricopeptide repeat domain in O-GlcNAc transferase targeting and protein substrate specificity.", "journal": "The Journal of biological chemistry", "date": "2003", "authors": "Iyer SP, Hart GW", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9UPV9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9UPV9" }, { "database": "GlyTouCan", "id": "G49108TO", "url": 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HDAC5 O-GlcNAcylation promotes osteogenesis by regulating the homeostasis of epigenetic modifications and proteolysis.", "journal": "Journal of orthopaedic translation", "date": "2025-01", "authors": "Du Yu, Gao Xiang, Chen Jianqiang, Chen Xinxin, Liu Hang, He Wenge, Liu Lu, Jiang Yue, He Baicheng, Deng Zhongliang, Liang Chao, Guo Fengjin", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9UQL6", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9UQL6" }, { "database": "O-GlcNAc Database", "id": "Q9Z2V6", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9Z2V6" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "39659899", "url": "https://glygen.org/publication/PubMed/39659899" } ] }, { "title": "Transient receptor potential canonical type 6 (TRPC6) O-GlcNAcylation at Threonine-221 plays potent role in channel regulation.", "journal": "iScience", "date": 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Activation in Prostate Cancer.", "journal": "Molecular cancer research : MCR", "date": "2022", "authors": "Poulose N, Forsythe N, Polonski A, Gregg G, Maguire S, Fuchs M, Minner S, Sauter G, McDade SS, Mills IG", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9Y4B6", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9Y4B6" }, { "database": "GlyTouCan", "id": "G49108TO", "url": "https://glytoucan.org/Structures/Glycans/G49108TO" } ], "reference": [ { "type": "PubMed", "id": "35348747", "url": "https://glygen.org/publication/PubMed/35348747" } ] }, { "title": "O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3.", "journal": "Immunity", "date": "2019", "authors": "Li X, Gong W, Wang H, Li T, Attri KS, Lewis RE, Kalil AC, Bhinderwala F, Powers R, Yin G, Herring LE, Asara JM, Lei YL, Yang X, Rodriguez DA, Yang M, Green DR, Singh PK, Wen H", "evidence": [ { "database": "O-GlcNAc Database", "id": 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